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Title Author Journal Name PubMedID Journal Abbreviation Publication Date
Ligand Identification in CryoEM and X-ray Maps Using Deep Learning. Karolczak J, Przybyłowska A, Szewczyk K, Taisner W, Heumann JM, Stowell MHB, Nowicki M, Brzezinski D bioRxiv : the preprint server for biology 39257821 bioRxiv 2024 Dec 9
Ligand identification in CryoEM and X-ray maps using deep learning. Karolczak J, Przybyłowska A, Szewczyk K, Taisner W, Heumann JM, Stowell MHB, Nowicki M, Brzezinski D Bioinformatics (Oxford, England) 39700427 Bioinformatics 2024 Dec 26
Architecture of the human erythrocyte ankyrin-1 complex. Vallese F, Kim K, Yen LY, Johnston JD, Noble AJ, Calì T, Clarke OB Nature structural & molecular biology 35835865 Nat Struct Mol Biol 2022 Jul
The structure of a Type III-A CRISPR-Cas effector complex reveals conserved and idiosyncratic contacts to target RNA and crRNA among Type III-A systems. Paraan M, Nasef M, Chou-Zheng L, Khweis SA, Schoeffler AJ, Hatoum-Aslan A, Stagg SM, Dunkle JA PloS one 37352230 PLoS One 2023
In situ cryo-FIB/SEM Specimen Preparation Using the Waffle Method. Klykov O, Bobe D, Paraan M, Johnston JD, Potter CS, Carragher B, Kopylov M, Noble AJ Bio-protocol 36618877 Bio Protoc 2022 Nov 5
Waffle Method: A general and flexible approach for improving throughput in FIB-milling. Kelley K, Raczkowski AM, Klykov O, Jaroenlak P, Bobe D, Kopylov M, Eng ET, Bhabha G, Potter CS, Carragher B, Noble AJ Nature communications 35387991 Nat Commun 2022 Apr 6
Better, Faster, Cheaper: Recent Advances in Cryo-Electron Microscopy. Chua EYD, Mendez JH, Rapp M, Ilca SL, Tan YZ, Maruthi K, Kuang H, Zimanyi CM, Cheng A, Eng ET, Noble AJ, Potter CS, Carragher B Annual review of biochemistry 35320683 Annu Rev Biochem 2022 Jun 21
Label-free visual proteomics: Coupling MS- and EM-based approaches in structural biology. Klykov O, Kopylov M, Carragher B, Heck AJR, Noble AJ, Scheltema RA Molecular cell 35063097 Mol Cell 2022 Jan 20
Cryo-Electron Microscopy Screening Automation across Multiple Grids using Smart Leginon. Sawh-Gopal A, Ishemgulova A, Chua EYD, Aragon MF, Mendez JH, Eng ET, Noble AJ Journal of visualized experiments : JoVE 38108412 J Vis Exp 2023 Dec 1
Micropatterning Transmission Electron Microscopy Grids to Direct Cell Positioning within Whole-Cell Cryo-Electron Tomography Workflows. Sibert BS, Kim JY, Yang JE, Wright ER Journal of visualized experiments : JoVE 34570100 J Vis Exp 2021 Sep 13
Handling Difficult Cryo-ET Samples: A Study with Primary Neurons from Drosophila melanogaster. Kim JY, Yang JE, Mitchell JW, English LA, Yang SZ, Tenpas T, Dent EW, Wildonger J, Wright ER Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 37966978 Microsc Microanal 2023 Dec 21
CorRelator: Interactive software for real-time high precision cryo-correlative light and electron microscopy. Yang JE, Larson MR, Sibert BS, Shrum S, Wright ER Journal of structural biology 33610654 J Struct Biol 2021 Jun
Assembly of respiratory syncytial virus matrix protein lattice and its coordination with fusion glycoprotein trimers. Sibert BS, Kim JY, Yang JE, Ke Z, Stobart CC, Moore ML, Wright ER Nature communications 39004634 Nat Commun 2024 Jul 14
Recent advances in correlative cryo-light and electron microscopy. Pierson JA, Yang JE, Wright ER Current opinion in structural biology 39366119 Curr Opin Struct Biol 2024 Dec
High-resolution Cryo-EM Structure Determination of a-Synuclein-A Prototypical Amyloid Fibril. Sanchez JC, Pierson JA, Borcik CG, Rienstra CM, Wright ER Bio-protocol 39959285 Bio Protoc 2025 Feb 5
Correlative montage parallel array cryo-tomography for in situ structural cell biology. Yang JE, Larson MR, Sibert BS, Kim JY, Parrell D, Sanchez JC, Pappas V, Kumar A, Cai K, Thompson K, Wright ER Nature methods 37723245 Nat Methods 2023 Oct
Cryo-electron tomography of stationary phase Burkholderia thailandensis. Khanna K, Welch MD microPublication biology 38725941 MicroPubl Biol 2024
Purification and Cryo-Electron Microscopy Analysis of Bacterial Appendages. Sanchez JC, Baumgardt JK, Wright ER Bio-protocol 39100595 Bio Protoc 2024 Jul 20
Atomic-level architecture of Caulobacter crescentus flagellar filaments provide evidence for multi-flagellin filament stabilization. Sanchez JC, Montemayor EJ, Ploscariu NT, Parrell D, Baumgardt JK, Yang JE, Sibert B, Cai K, Wright ER bioRxiv : the preprint server for biology 37503001 bioRxiv 2023 Jul 10
Quantitative Analysis of Rhodobacter sphaeroides Storage Organelles via Cryo-Electron Tomography and Light Microscopy. Parrell D, Olson J, Lemke RA, Donohue TJ, Wright ER Biomolecules 39199393 Biomolecules 2024 Aug 14
In situ crystalline structure of the human eosinophil major basic protein-1. Yang JE, Mitchell JM, Bingman CA, Mosher DF, Wright ER bioRxiv : the preprint server for biology 39416224 bioRxiv 2024 Oct 11
Molecular sociology of virus-induced cellular condensates supporting reovirus assembly and replication. Liu X, Xia X, Martynowycz MW, Gonen T, Zhou ZH Nature communications 39639006 Nat Commun 2024 Dec 6
High-Resolution Cryo-EM Structure Determination of α-synuclein - A Prototypical Amyloid Fibril. Sanchez JC, Pierson J, Borcik CG, Rienstra CM, Wright ER bioRxiv : the preprint server for biology 39345396 bioRxiv 2024 Sep 19
The role of CenKR in the coordination of Rhodobacter sphaeroides cell elongation and division. Lakey BD, Alberge F, Parrell D, Wright ER, Noguera DR, Donohue TJ mBio 37283520 mBio 2023 Aug 31
Integrated Fluorescence Microscopy (iFLM) for Cryo-FIB-milling and In-situ Cryo-ET. Yang J, Vrbovská V, Franke T, Sibert B, Larson M, Hall A, Rigort A, Mitchels J, Wright ER bioRxiv : the preprint server for biology 37502891 bioRxiv 2023 Jul 12
Handling difficult cryo-ET samples: A study with primary neurons from Drosophila melanogaster. Kim JY, Yang JE, Mitchell JW, English LA, Yang SZ, Tenpas T, Dent EW, Wildonger J, Wright ER bioRxiv : the preprint server for biology 37502991 bioRxiv 2023 Jul 11
Tad and toxin-coregulated pilus structures reveal unexpected diversity in bacterial type IV pili. Sonani RR, Sanchez JC, Baumgardt JK, Kundra S, Wright ER, Craig L, Egelman EH Proceedings of the National Academy of Sciences of the United States of America 38011558 Proc Natl Acad Sci U S A 2023 Dec 5
The mating pilus of E. coli pED208 acts as a conduit for ssDNA during horizontal gene transfer. Beltrán L, Torsilieri H, Patkowski JB, Yang JE, Casanova J, Costa TRD, Wright ER, Egelman EH mBio 38051116 mBio 2024 Jan 16
Cost-benefit analysis of cryogenic electron tomography subtomogram averaging of chaperonin MmCpn at near atomic resolution. Zhao Y, Schmid MF, Chiu W Structure (London, England : 1993) 39644888 Structure 2025 Feb 6
Extracellular filaments revealed by affinity capture cryo-electron tomography. Engel L, Zaoralová M, Zhou M, Dunn AR, Oliver SL bioRxiv : the preprint server for biology 37577490 bioRxiv 2024 Sep 5
Cyanobacteria and Chloroflexota cooperate to structure light-responsive biofilms. Bunbury F, Rivas C, Calatrava V, Malkovskiy AV, Joubert LM, Parvate AD, Evans JE, Grossman AR, Bhaya D Proceedings of the National Academy of Sciences of the United States of America 39879238 Proc Natl Acad Sci U S A 2025 Feb 4
In-Situ Structure and Topography of AMPA Receptor Scaffolding Complexes Visualized by CryoET. Held RG, Liang J, Esquivies L, Khan YA, Wang C, Azubel M, Brunger AT bioRxiv : the preprint server for biology 39464045 bioRxiv 2024 Oct 22
Dramatic Changes in Mitochondrial Subcellular Location and Morphology Accompany Activation of the CO(2) Concentrating Mechanism. Findinier J, Joubert LM, Schmid MF, Malkovskiy A, Chiu W, Burlacot A, Grossman AR bioRxiv : the preprint server for biology 38585955 bioRxiv 2024 Mar 27
Nanoscale architecture of synaptic vesicles and scaffolding complexes revealed by cryo-electron tomography. Held RG, Liang J, Brunger AT Proceedings of the National Academy of Sciences of the United States of America 38923992 Proc Natl Acad Sci U S A 2024 Jul 2
Dramatic changes in mitochondrial subcellular location and morphology accompany activation of the CO(2) concentrating mechanism. Findinier J, Joubert LM, Fakhimi N, Schmid MF, Malkovskiy AV, Chiu W, Burlacot A, Grossman AR Proceedings of the National Academy of Sciences of the United States of America 39405346 Proc Natl Acad Sci U S A 2024 Oct 22
Structure of the Native Muscle-type Nicotinic Receptor and Inhibition by Snake Venom Toxins. Rahman MM, Teng J, Worrell BT, Noviello CM, Lee M, Karlin A, Stowell MHB, Hibbs RE Neuron 32275860 Neuron 2020 Jun 17
Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement. Patel AB, Moore CM, Greber BJ, Luo J, Zukin SA, Ranish J, Nogales E eLife 31886770 Elife 2019 Dec 30
Architecture of the linker-scaffold in the nuclear pore. Petrovic S, Samanta D, Perriches T, Bley CJ, Thierbach K, Brown B, Nie S, Mobbs GW, Stevens TA, Liu X, Tomaleri GP, Schaus L, Hoelz A Science (New York, N.Y.) 35679425 Science 2022 Jun 10
Subdomain cryo-EM structure of nodaviral replication protein A crown complex provides mechanistic insights into RNA genome replication. Unchwaniwala N, Zhan H, Pennington J, Horswill M, den Boon JA, Ahlquist P Proceedings of the National Academy of Sciences of the United States of America 32690711 Proc Natl Acad Sci U S A 2020 Aug 4
Structure and gating mechanism of the α7 nicotinic acetylcholine receptor. Noviello CM, Gharpure A, Mukhtasimova N, Cabuco R, Baxter L, Borek D, Sine SM, Hibbs RE Cell 33735609 Cell 2021 Apr 15
Conformational landscape of the yeast SAGA complex as revealed by cryo-EM. Vasyliuk D, Felt J, Zhong ED, Berger B, Davis JH, Yip CK Scientific reports 35853968 Sci Rep 2022 Jul 19
Visualization of conformational changes and membrane remodeling leading to genome delivery by viral class-II fusion machinery. Mangala Prasad V, Blijleven JS, Smit JM, Lee KK Nature communications 35970990 Nat Commun 2022 Aug 15
Structural basis for APE1 processing DNA damage in the nucleosome. Weaver TM, Hoitsma NM, Spencer JJ, Gakhar L, Schnicker NJ, Freudenthal BD Nature communications 36104361 Nat Commun 2022 Sep 14
Structural basis for inhibition of the Cation-chloride cotransporter NKCC1 by the diuretic drug bumetanide. Zhao Y, Roy K, Vidossich P, Cancedda L, De Vivo M, Forbush B, Cao E Nature communications 35585053 Nat Commun 2022 May 18
Active conformation of the p97-p47 unfoldase complex. Xu Y, Han H, Cooney I, Guo Y, Moran NG, Zuniga NR, Price JC, Hill CP, Shen PS Nature communications 35552390 Nat Commun 2022 May 12
Molecular structures and conformations of protocadherin-15 and its complexes on stereocilia elucidated by cryo-electron tomography. Elferich J, Clark S, Ge J, Goehring A, Matsui A, Gouaux E eLife 34964715 Elife 2021 Dec 29
Structural basis of long-range to short-range synaptic transition in NHEJ. Chen S, Lee L, Naila T, Fishbain S, Wang A, Tomkinson AE, Lees-Miller SP, He Y Nature 33854234 Nature 2021 May
Structural insight on assembly-line catalysis in terpene biosynthesis. Faylo JL, van Eeuwen T, Kim HJ, Gorbea Colón JJ, Garcia BA, Murakami K, Christianson DW Nature communications 34108468 Nat Commun 2021 Jun 9
Structural basis for potassium transport in prokaryotes by KdpFABC. Sweet ME, Larsen C, Zhang X, Schlame M, Pedersen BP, Stokes DL Proceedings of the National Academy of Sciences of the United States of America 34272288 Proc Natl Acad Sci U S A 2021 Jul 20
The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter. Plenge P, Yang D, Salomon K, Laursen L, Kalenderoglou IE, Newman AH, Gouaux E, Coleman JA, Loland CJ Nature communications 34417466 Nat Commun 2021 Aug 20
Structure of the human Mediator-bound transcription preinitiation complex. Abdella R, Talyzina A, Chen S, Inouye CJ, Tjian R, He Y Science (New York, N.Y.) 33707221 Science 2021 Apr 2
A Robust Single-Particle Cryo-Electron Microscopy (cryo-EM) Processing Workflow with cryoSPARC, RELION, and Scipion. DiIorio MC, Kulczyk AW Journal of visualized experiments : JoVE 35104261 J Vis Exp 2022 Jan 31
Structural mechanism of allosteric activation of TRPML1 by PI(3,5)P(2) and rapamycin. Gan N, Han Y, Zeng W, Wang Y, Xue J, Jiang Y Proceedings of the National Academy of Sciences of the United States of America 35131932 Proc Natl Acad Sci U S A 2022 Feb 15
Structural basis for flagellin induced NAIP5 activation. Paidimuddala B, Cao J, Zhang L bioRxiv : the preprint server for biology 37398004 bioRxiv 2023 Jun 13
Structural interplay of anesthetics and paralytics on muscle nicotinic receptors. Goswami U, Rahman MM, Teng J, Hibbs RE Nature communications 37264005 Nat Commun 2023 Jun 1
Molecular pathway and structural mechanism of human oncochannel TRPV6 inhibition by the phytocannabinoid tetrahydrocannabivarin. Neuberger A, Trofimov YA, Yelshanskaya MV, Khau J, Nadezhdin KD, Khosrof LS, Krylov NA, Efremov RG, Sobolevsky AI Nature communications 37532722 Nat Commun 2023 Aug 2
Energy Coupling and Stoichiometry of Zn(2+)/H(+) Antiport by the Cation Diffusion Facilitator YiiP. Hussein A, Fan S, Lopez-Redondo M, Kenney I, Zhang X, Beckstein O, Stokes DL bioRxiv : the preprint server for biology 36865113 bioRxiv 2023 Jul 31
Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome-depleted regions. Donovan BT, Chen H, Eek P, Meng Z, Jipa C, Tan S, Bai L, Poirier MG Molecular cell 36996811 Mol Cell 2023 Apr 20
Batch Production of High-Quality Graphene Grids for Cryo-EM: Cryo-EM Structure of Methylococcus capsulatus Soluble Methane Monooxygenase Hydroxylase. Ahn E, Kim B, Park S, Erwin AL, Sung SH, Hovden R, Mosalaganti S, Cho US ACS nano 36926824 ACS Nano 2023 Mar 28
Sensory specializations drive octopus and squid behaviour. Kang G, Allard CAH, Valencia-Montoya WA, van Giesen L, Kim JJ, Kilian PB, Bai X, Bellono NW, Hibbs RE Nature 37045917 Nature 2023 Apr
Cryo-EM structure of the human Sirtuin 6-nucleosome complex. Chio US, Rechiche O, Bryll AR, Zhu J, Leith EM, Feldman JL, Peterson CL, Tan S, Armache JP Science advances 37058572 Sci Adv 2023 Apr 14
Extended regulation interface coupled to the allosteric network and disease mutations in the PP2A-B56δ holoenzyme. Wu CG, Balakrishnan VK, Parihar PS, Konovolov K, Chen YC, Merrill RA, Wei H, Carragher B, Sundaresan R, Cui Q, Wadzinski BE, Swingle MR, Musiyenko A, Honkanen R, Chung WK, Suzuki A, Strack S, Huang X, Xing Y bioRxiv : the preprint server for biology 37066309 bioRxiv 2023 Apr 5
Focusing antibody responses to the fusion peptide in rhesus macaques. Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Greene KM, Allen JD, Ngo JT, Choe Y, Nogal B, Silva M, Bhiman J, Pauthner M, Irvine DJ, Montefiori D, Crispin M, Burton DR, Silvestri G, Crotty S, Ward AB bioRxiv : the preprint server for biology 37425865 bioRxiv 2023 Jun 27
Cryo-EM reveals the molecular basis oflaminin polymerization and LN-lamininopathies. Kulczyk AW, McKee KK, Zhang X, Bizukojc I, Yu YQ, Yurchenco PD Nature communications 36658135 Nat Commun 2023 Jan 19
Human TRPV1 structure and inhibition by the analgesic SB-366791. Neuberger A, Oda M, Nikolaev YA, Nadezhdin KD, Gracheva EO, Bagriantsev SN, Sobolevsky AI Nature communications 37117175 Nat Commun 2023 Apr 28
Cryo-EM Structure of AAV2 Rep68 bound to integration site AAVS1: Insights into the mechanism of DNA melting. Jaiswal R, Santosh V, Braud B, Washington A, Escalante CR bioRxiv : the preprint server for biology 38617369 bioRxiv 2024 Apr 2
Selected humanization of yeast U1 snRNP leads to global suppression of pre-mRNA splicing and mitochondrial dysfunction in the budding yeast. Chalivendra S, Shi S, Li X, Kuang Z, Giovinazzo J, Zhang L, Rossi J, Wang J, Saviola AJ, Welty R, Liu S, Vaeth KF, Zhou ZH, Hansen KC, Taliaferro JM, Zhao R RNA (New York, N.Y.) 38688558 RNA 2024 Jul 16
Dual receptor-sites reveal the structural basis for hyperactivation of sodium channels by poison-dart toxin batrachotoxin. Tonggu L, Wisedchaisri G, Gamal El-Din TM, Lenaeus MJ, Logan MM, Toma T, Du Bois J, Zheng N, Catterall WA Nature communications 38485923 Nat Commun 2024 Mar 14
A strategic approach for efficient cryo-EM grid optimization using design of experiments. Haynes RM, Myers J, López CS, Evans J, Davulcu O, Yoshioka C Journal of structural biology 38364988 J Struct Biol 2024 Feb 15
Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Hu Q, Zhao D, Cui G, Bhandari J, Thompson JR, Botuyan MV, Mer G Molecular cell 38242129 Mol Cell 2024 Mar 7
AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. Caffrey B, Zhu X, Berezuk A, Tuttle K, Chittori S, Subramaniam S The Journal of biological chemistry 34520757 J Biol Chem 2021 Oct
The Structure of an AAV5-AAVR Complex at 2.5 Å Resolution: Implications for Cellular Entry and Immune Neutralization of AAV Gene Therapy Vectors. Silveria MA, Large EE, Zane GM, White TA, Chapman MS Viruses 33218165 Viruses 2020 Nov 18
Structure of bacterial phospholipid transporter MlaFEDB with substrate bound. Coudray N, Isom GL, MacRae MR, Saiduddin MN, Bhabha G, Ekiert DC eLife 33236984 Elife 2020 Nov 25
Structural principles of B cell antigen receptor assembly. Dong Y, Pi X, Bartels-Burgahn F, Saltukoglu D, Liang Z, Yang J, Alt FW, Reth M, Wu H Nature 36228656 Nature 2022 Dec
Structural basis of broad-spectrum β-lactam resistance in Staphylococcus aureus. Alexander JAN, Worrall LJ, Hu J, Vuckovic M, Satishkumar N, Poon R, Sobhanifar S, Rosell FI, Jenkins J, Chiang D, Mosimann WA, Chambers HF, Paetzel M, Chatterjee SS, Strynadka NCJ Nature 36599987 Nature 2023 Jan
Structural basis of promiscuous substrate transport by Organic Cation Transporter 1. Zeng YC, Sobti M, Quinn A, Smith NJ, Brown SHJ, Vandenberg JI, Ryan RM, O'Mara ML, Stewart AG Nature communications 37821493 Nat Commun 2023 Oct 11
Antiviral drug recognition and elevator-type transport motions of CNT3. Wright NJ, Zhang F, Suo Y, Kong L, Yin Y, Fedor JG, Sharma K, Borgnia MJ, Im W, Lee SY Nature chemical biology 38418906 Nat Chem Biol 2024 Sep
Structural basis of selective TRPM7 inhibition by the anticancer agent CCT128930. Nadezhdin KD, Correia L, Shalygin A, Aktolun M, Neuberger A, Gudermann T, Kurnikova MG, Chubanov V, Sobolevsky AI Cell reports 38615321 Cell Rep 2024 Apr 23
Amyloid fibril polymorphism in the heart of an ATTR amyloidosis patient with polyneuropathy attributed to the V122Δ variant. Ahmed Y, Nguyen BA, Afrin S, Singh V, Evers B, Singh P, Pedretti R, Wang L, Bassett P, Del Carmen Fernandez-Ramirez M, Pekala M, Kluve-Beckerman B, Saelices L bioRxiv : the preprint server for biology 38766262 bioRxiv 2024 May 10
ATTRv-V30M Type A amyloid fibrils from heart and nerves exhibit structural homogeneity. Nguyen BA, Afrin S, Yakubovska A, Singh V, Alicea JV, Kunach P, Singh P, Pekala M, Ahmed Y, Fernandez-Ramirez MDC, Hernandez LOC, Pedretti R, Bassett P, Wang L, Lemoff A, Villalon L, Kluve-Beckerman B, Saelices L bioRxiv : the preprint server for biology 38798361 bioRxiv 2024 May 14
Structure of an open K(ATP) channel reveals tandem PIP(2) binding sites mediating the Kir6.2 and SUR1 regulatory interface. Driggers CM, Kuo YY, Zhu P, ElSheikh A, Shyng SL Nature communications 38509107 Nat Commun 2024 Mar 20
Structure of the human dopamine transporter and mechanisms of inhibition. Srivastava DK, Navratna V, Tosh DK, Chinn A, Sk MF, Tajkhorshid E, Jacobson KA, Gouaux E Nature 39112705 Nature 2024 Aug
AI-Based Discovery and CryoEM Structural Elucidation of a K(ATP) Channel Pharmacochaperone. ElSheikh A, Driggers CM, Truong HH, Yang Z, Allen J, Henriksen N, Walczewska-Szewc K, Shyng SL bioRxiv : the preprint server for biology 39282384 bioRxiv 2025 Feb 7
Streptococcus pneumoniae GAPN is a key metabolic player necessary for host infection. Lee E, Saviola A, Bevers S, Redzic JS, Maroney SP, Shaw S, Tamkin E, Fulte S, Nemkov T, Meyer N, D'Alessandro A, Hansen KC, Clark SE, Eisenmesser E Protein science : a publication of the Protein Society 39660954 Protein Sci 2025 Jan
Structural insights into subunit-dependent functional regulation in epithelial sodium channels. Houser A, Baconguis I Structure (London, England : 1993) 39667931 Structure 2025 Feb 6
Cryo-EM structures of the human P2X1 receptor reveal subtype-specific architecture and antagonism by supramolecular ligand-binding. Oken AC, Lisi NE, Ditter IA, Shi H, Nechiporuk NA, Mansoor SE Nature communications 39353889 Nat Commun 2024 Oct 1
Trapping of spermine, Kukoamine A, and polyamine toxin blockers in GluK2 kainate receptor channels. Gangwar SP, Yelshanskaya MV, Aktolun M, Yen LY, Newton TP, Strømgaard K, Kurnikova MG, Sobolevsky AI Nature communications 39592599 Nat Commun 2024 Nov 26
Human P2X4 receptor gating is modulated by a stable cytoplasmic cap and a unique allosteric pocket. Shi H, Ditter IA, Oken AC, Mansoor SE Science advances 39823330 Sci Adv 2025 Jan 17
Discovery of three novel neutralizing antibody epitopes on the human astrovirus capsid spike and mechanistic insights into virus neutralization. Lanning S, Aguilar-Hernández N, Serrão VHB, López T, O'Rourke SM, Lentz A, Ricemeyer L, Espinosa R, López S, Arias CF, DuBois RM Journal of virology 39846739 J Virol 2025 Feb 25
Structural basis for human NKCC1 inhibition by loop diuretic drugs. Zhao Y, Vidossich P, Forbush B, Ma J, Rinehart J, De Vivo M, Cao E The EMBO journal 39875725 EMBO J 2025 Mar
Cryo-EM structure of AAV2 Rep68 bound to integration site AAVS1: insights into the mechanism of DNA melting. Jaiswal R, Braud B, Hernandez-Ramirez KC, Santosh V, Washington A, Escalante CR Nucleic acids research 39883011 Nucleic Acids Res 2025 Jan 24
Cryo-EM structures provide insight into how E. coli F(1)F(o) ATP synthase accommodates symmetry mismatch. Sobti M, Walshe JL, Wu D, Ishmukhametov R, Zeng YC, Robinson CV, Berry RM, Stewart AG Nature communications 32457314 Nat Commun 2020 May 26
Production and purification of ATP-sensitive potassium channel particles for cryo-electron microscopy. Driggers CM, Shyng SL Methods in enzymology 34099169 Methods Enzymol 2021
TRPV3 expression and purification for structure determination by Cryo-EM. Neuberger A, Nadezhdin KD, Sobolevsky AI Methods in enzymology 34059288 Methods Enzymol 2021
Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes. Robert Hollingsworth L, David L, Li Y, Griswold AR, Ruan J, Sharif H, Fontana P, Orth-He EL, Fu TM, Bachovchin DA, Wu H Nature communications 33420033 Nat Commun 2021 Jan 8
Architecture and assembly mechanism of native glycine receptors. Zhu H, Gouaux E Nature 34555840 Nature 2021 Nov
Structural and dynamic mechanisms of GABA(A) receptor modulators with opposing activities. Zhu S, Sridhar A, Teng J, Howard RJ, Lindahl E, Hibbs RE Nature communications 35933426 Nat Commun 2022 Aug 6
Mechanism of NAIP-NLRC4 inflammasome activation revealed by cryo-EM structure of unliganded NAIP5. Paidimuddala B, Cao J, Nash G, Xie Q, Wu H, Zhang L Nature structural & molecular biology 36604500 Nat Struct Mol Biol 2023 Feb
A substrate-induced gating mechanism is conserved among Gram-positive IgA1 metalloproteases. Redzic JS, Rahkola J, Tran N, Holyoak T, Lee E, Martín-Galiano AJ, Meyer N, Zheng H, Eisenmesser E Communications biology 36336763 Commun Biol 2022 Nov 7
The promise of cryo-EM to explore RNA structural dynamics. Bonilla SL, Kieft JS Journal of molecular biology 36049551 J Mol Biol 2022 Sep 30
Structurally derived universal mechanism for the catalytic cycle of the tail-anchored targeting factor Get3. Fry MY, Najdrová V, Maggiolo AO, Saladi SM, Doležal P, Clemons WM Jr Nature structural & molecular biology 35851188 Nat Struct Mol Biol 2022 Aug
30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC. Srinivas P, Nosrati M, Zelinskaya N, Dey D, Comstock LR, Dunham CM, Conn GL bioRxiv : the preprint server for biology 36993224 bioRxiv 2023 Apr 30
Structural basis of sensory receptor evolution in octopus. Allard CAH, Kang G, Kim JJ, Valencia-Montoya WA, Hibbs RE, Bellono NW Nature 37045920 Nature 2023 Apr
BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL. Xia M, David L, Teater M, Gutierrez J, Wang X, Meydan C, Lytle A, Slack GW, Scott DW, Morin RD, Onder O, Elenitoba-Johnson KSJ, Zamponi N, Cerchietti L, Lu T, Philippar U, Fontan L, Wu H, Melnick AM Cancer discovery 35658124 Cancer Discov 2022 Aug 5
Methotrexate recognition by the human reduced folate carrier SLC19A1. Wright NJ, Fedor JG, Zhang H, Jeong P, Suo Y, Yoo J, Hong J, Im W, Lee SY Nature 36071163 Nature 2022 Sep
An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. Morgan CE, Zhang Z, Bonomo RA, Yu EW mBio 35100868 mBio 2021 Feb 22
NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation. Andreeva L, David L, Rawson S, Shen C, Pasricha T, Pelegrin P, Wu H Cell 34861190 Cell 2021 Dec 22
Cryo-EM reveals unique structural features of the FhuCDB Escherichia coli ferrichrome importer. Hu W, Zheng H Communications biology 34887516 Commun Biol 2021 Dec 9
Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases. Kato K, Ahmad S, Zhu Z, Young JM, Mu X, Park S, Malik HS, Hur S Molecular cell 33373584 Mol Cell 2021 Feb 4
A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel. Liu C, Reese R, Vu S, Rougé L, Shields SD, Kakiuchi-Kiyota S, Chen H, Johnson K, Shi YP, Chernov-Rogan T, Greiner DMZ, Kohli PB, Hackos D, Brillantes B, Tam C, Li T, Wang J, Safina B, Magnuson S, Volgraf M, Payandeh J, Zheng J, Rohou A, Chen J Neuron 33152265 Neuron 2021 Jan 20
Recovery of particulate methane monooxygenase structure and activity in a lipid bilayer. Koo CW, Tucci FJ, He Y, Rosenzweig AC Science (New York, N.Y.) 35298269 Science 2022 Mar 18
Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II. Yang C, Fujiwara R, Kim HJ, Basnet P, Zhu Y, Gorbea Colón JJ, Steimle S, Garcia BA, Kaplan CD, Murakami K Molecular cell 35051353 Mol Cell 2022 Feb 3
Structural Basis for Virulence Activation of Francisella tularensis. Travis BA, Ramsey KM, Prezioso SM, Tallo T, Wandzilak JM, Hsu A, Borgnia M, Bartesaghi A, Dove SL, Brennan RG, Schumacher MA Molecular cell 33217319 Mol Cell 2021 Jan 7
Structural insights into opposing actions of neurosteroids on GABA(A) receptors. Legesse DH, Fan C, Teng J, Zhuang Y, Howard RJ, Noviello CM, Lindahl E, Hibbs RE Nature communications 37607940 Nat Commun 2023 Aug 22
Structure and assembly of a bacterial gasdermin pore. Johnson AG, Mayer ML, Schaefer SL, McNamara-Bordewick NK, Hummer G, Kranzusch PJ bioRxiv : the preprint server for biology 37131678 bioRxiv 2023 Oct 26
Structures of the TMC-1 complex illuminate mechanosensory transduction. Jeong H, Clark S, Goehring A, Dehghani-Ghahnaviyeh S, Rasouli A, Tajkhorshid E, Gouaux E Nature 36224384 Nature 2022 Oct
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