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The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.

Title Author Journal Name PubMedID Journal Abbreviation Publication Date
Iron(iii) chloride-catalyzed activation of glycosyl chlorides. Geringer SA, Demchenko AV Organic & biomolecular chemistry 30430182 Org Biomol Chem 2018 Dec 5
HPLC-assisted automated oligosaccharide synthesis: the implementation of the two-way split valve as a mode of complete automation. Panza M, Stine KJ, Demchenko AV Chemical communications (Cambridge, England) 31930269 Chem Commun (Camb) 2020 Jan 28
Investigation of Glycosyl Nitrates as Building Blocks for Chemical Glycosylation. Wang T, Singh Y, Stine KJ, Demchenko AV European journal of organic chemistry 31341403 European J Org Chem 2018 Dec 19
Triflic acid-mediated synthesis of thioglycosides. Escopy S, Singh Y, Demchenko AV Organic & biomolecular chemistry 31490529 Org Biomol Chem 2019 Sep 28
The chemical synthesis of human milk oligosaccharides: Lacto-N-tetraose (Galβ1→3GlcNAcβ1→3Galβ1→4Glc). Bandara MD, Stine KJ, Demchenko AV Carbohydrate research 31585319 Carbohydr Res 2019 Dec 1
Glycosyl nitrates in synthesis: streamlined access to glucopyranose building blocks differentiated at C-2. Wang T, Nigudkar SS, Yasomanee JP, Rath NP, Stine KJ, Demchenko AV Organic & biomolecular chemistry 29693690 Org Biomol Chem 2018 May 15
Intramolecular glycosylation. Jia XG, Demchenko AV Beilstein journal of organic chemistry 29062425 Beilstein J Org Chem 2017
Investigation of the H-bond-mediated aglycone delivery reaction in application to the synthesis of β-glucosides. Mannino MP, Yasomanee JP, Demchenko AV Carbohydrate research 30286335 Carbohydr Res 2018 Dec
Facile and robust methods for the regioselective acylation of N-acetylneuraminic acid. Shadrick M, Yu C, Geringer S, Ritter S, Behm A, Cox A, Lohman M, De Meo C New journal of chemistry = Nouveau journal de chimie 30147293 New J Chem 2018 Sep 7
Application of Porous Materials to Carbohydrate Chemistry and Glycoscience. Stine KJ Advances in carbohydrate chemistry and biochemistry 29173727 Adv Carbohydr Chem Biochem 2017
Extending the S-benzimidazolyl (SBiz) platform: N-alkylated SBiz glycosyl donors with the universal activation profile. Hasty SJ, Rath NP, Demchenko AV Pure and applied chemistry. Chimie pure et appliquee 29861508 Pure Appl Chem 2017 Sep
Automated Chemical Oligosaccharide Synthesis: Novel Approach to Traditional Challenges. Panza M, Pistorio SG, Stine KJ, Demchenko AV Chemical reviews 29953217 Chem Rev 2018 Sep 12
OFox imidates as versatile glycosyl donors for chemical glycosylation. Nigudkar SS, Wang T, Pistorio SG, Yasomanee JP, Stine KJ, Demchenko AV Organic & biomolecular chemistry 27808325 Org Biomol Chem 2017 Jan 4
Manual and Automated Syntheses of the N-Linked Glycoprotein Core Glycans. Pistorio SG, Geringer SA, Stine KJ, Demchenko AV The Journal of organic chemistry 31066275 J Org Chem 2019 Jun 7
Chemical synthesis of human milk oligosaccharides: lacto-N-neohexaose (Galβ1 → 4GlcNAcβ1→)(2) 3,6Galβ1 → 4Glc. Bandara MD, Stine KJ, Demchenko AV Organic & biomolecular chemistry 32048706 Org Biomol Chem 2020 Mar 4
A pH sensitive thiolated β-cyclodextrin-modified nanoporous gold for controlled release of doxorubicin. Neupane D, Bhattarai JK, Demchenko AV, Stine KJ Journal of drug delivery science and technology 32922527 J Drug Deliv Sci Technol 2020 Dec
The development of a dedicated polymer support for the solid-phase oligosaccharide synthesis. Panza M , Neupane D , Stine KJ , Demchenko AV Chemical communications (Cambridge, England) 32785304 Chem Commun (Camb) 2020 Sep 16
Comparative Study on the Effects of Picoloyl Groups in Sialylations Based on Their Substitution Pattern. Jones B, Behm A, Shadrick M, Geringer SA, Escopy S, Lohman M, De Meo C The Journal of organic chemistry 31718181 J Org Chem 2019 Dec 6
Regenerative Glycosylation. Singh Y, Wang T, Geringer SA, Stine KJ, Demchenko AV The Journal of organic chemistry 29227649 J Org Chem 2018 Jan 5
A Streamlined Regenerative Glycosylation Reaction: Direct, Acid-Free Activation of Thioglycosides. Escopy S, Singh Y, Stine KJ, Demchenko AV Chemistry (Weinheim an der Bergstrasse, Germany) 32804435 Chemistry 2021 Jan 4
HPLC-Assisted Automated Oligosaccharide Synthesis: Implementation of the Autosampler as a Mode of the Reagent Delivery. Pistorio SG, Nigudkar SS, Stine KJ, Demchenko AV The Journal of organic chemistry 27575052 J Org Chem 2016 Oct 7
Koenigs-Knorr Glycosylation Reaction Catalyzed by Trimethylsilyl Trifluoromethanesulfonate. Singh Y, Demchenko AV Chemistry (Weinheim an der Bergstrasse, Germany) 30407673 Chemistry 2019 Jan 28
The chemical synthesis of human milk oligosaccharides: Lacto-N-neotetraose (Galβ1→4GlcNAcβ1→3Galβ1→4Glc). Bandara MD, Stine KJ, Demchenko AV Carbohydrate research 31319351 Carbohydr Res 2019 Sep 1
Chemical Synthesis of Human Milk Oligosaccharides: Lacto-N-hexaose Galβ1→3GlcNAcβ1→3 [Galβ1→4GlcNAcβ1→6] Galβ1→4Glc. Bandara MD, Stine KJ, Demchenko AV The Journal of organic chemistry 31749363 J Org Chem 2019 Dec 20
HPLC-Based Automated Synthesis and Purification of Carbohydrates. Kashiwagi GA, Petrosilli L, Escopy S, Lay L, Stine KJ, De Meo C, Demchenko AV Chemistry (Weinheim an der Bergstrasse, Germany) 38684455 Chemistry 2024 Aug 1
Synthesis of 2-azido-2-deoxy- and 2-acetamido-2-deoxy-D-manno derivatives as versatile building blocks. Alex C, Visansirikul S, Zhang Y, Yasomanee JP, Codee J, Demchenko AV Carbohydrate research 31901454 Carbohydr Res 2020 Feb
Immobilization of glycans on solid surfaces for application in glycomics. O'Neil CL, Stine KJ, Demchenko AV Journal of carbohydrate chemistry 30505067 J Carbohydr Chem 2018
Bromine-Promoted Glycosidation of Conformationally Superarmed Thioglycosides. Panza M, Civera M, Yasomanee JP, Belvisi L, Demchenko AV Chemistry (Weinheim an der Bergstrasse, Germany) 31286579 Chemistry 2019 Sep 12
Synthesis of carbohydrate building blocks via regioselective uniform protection/deprotection strategies. Wang T, Demchenko AV Organic & biomolecular chemistry 31044205 Org Biomol Chem 2019 May 28
Biochemical characterization of Helicobacter pylori α1-3-fucosyltransferase and its application in the synthesis of fucosylated human milk oligosaccharides. Bai J, Wu Z, Sugiarto G, Gadi MR, Yu H, Li Y, Xiao C, Ngo A, Zhao B, Chen X, Guan W Carbohydrate research 31132553 Carbohydr Res 2019 Jul 1
Regioselective One-Pot Multienzyme (OPME) Chemoenzymatic Strategies for Systematic Synthesis of Sialyl Core 2 Glycans. Santra A, Li Y, Ghosh T, Li R, Yu H, Chen X ACS catalysis 31304048 ACS Catal 2019 Jan 4
One-pot multienzyme (OPME) chemoenzymatic synthesis of brain ganglioside glycans with human ST3GAL II expressed in E. coli. Yang X, Yu H, Yang X, Kooner AS, Yuan Y, Luu B, Chen X ChemCatChem 35784007 ChemCatChem 2022 Jan 21
Recent progress in synthesis of carbohydrates with sugar nucleotide-dependent glycosyltransferases. Na L, Li R, Chen X Current opinion in chemical biology 33310623 Curr Opin Chem Biol 2021 Apr
Strategies for chemoenzymatic synthesis of carbohydrates. Li W, McArthur JB, Chen X Carbohydrate research 30529493 Carbohydr Res 2019 Jan 15
Chemoenzymatic synthesis of para-nitrophenol (pNP)-tagged α2-8-sialosides and high-throughput substrate specificity studies of α2-8-sialidases. Tasnima N, Yu H, Li Y, Santra A, Chen X Organic & biomolecular chemistry 27924345 Org Biomol Chem 2016 Dec 20
Synthesis of N-Glycolylneuraminic Acid (Neu5Gc) and Its Glycosides. Kooner AS, Yu H, Chen X Frontiers in immunology 31555264 Front Immunol 2019
A Bacterial β1-3-Galactosyltransferase Enables Multigram-Scale Synthesis of Human Milk Lacto-N-tetraose (LNT) and Its Fucosides. McArthur JB, Yu H, Chen X ACS catalysis 33408950 ACS Catal 2019 Dec 6
Catalytic Cycle of Neisseria meningitidis CMP-Sialic Acid Synthetase Illustrated by High-Resolution Protein Crystallography. Matthews MM, McArthur JB, Li Y, Yu H, Chen X, Fisher AJ Biochemistry 31583886 Biochemistry 2020 Sep 1
H. pylori α1-3/4-fucosyltransferase (Hp3/4FT)-catalyzed one-pot multienzyme (OPME) synthesis of Lewis antigens and human milk fucosides. Yu H, Li Y, Wu Z, Li L, Zeng J, Zhao C, Wu Y, Tasnima N, Wang J, Liu H, Gadi MR, Guan W, Wang PG, Chen X Chemical communications (Cambridge, England) 28936496 Chem Commun (Camb) 2017 Oct 5
Substrate and Process Engineering for Biocatalytic Synthesis and Facile Purification of Human Milk Oligosaccharides. Bai Y, Yang X, Yu H, Chen X ChemSusChem 35100486 ChemSusChem 2022 May 6
Recent progress in chemical synthesis of bacterial surface glycans. Li R, Yu H, Chen X Current opinion in chemical biology 32920523 Curr Opin Chem Biol 2020 Oct
Chemoenzymatic Synthesis and Facile Purification of Gangliosides. Bai Y, Yu H, Chen X Current protocols 33760402 Curr Protoc 2021 Mar
Converting Pasteurella multocidaα2-3-sialyltransferase 1 (PmST1) to a regioselective α2-6-sialyltransferase by saturation mutagenesis and regioselective screening. McArthur JB, Yu H, Zeng J, Chen X Organic & biomolecular chemistry 28134951 Org Biomol Chem 2017 Feb 21
Highly efficient chemoenzymatic synthesis and facile purification of α-Gal pentasaccharyl ceramide Galα3nLc(4)βCer. Santra A, Li Y, Yu H, Slack TJ, Wang PG, Chen X Chemical communications (Cambridge, England) 28695219 Chem Commun (Camb) 2017 Jul 20
Chemoenzymatic synthesis of Neu5Ac9NAc-containing α2-3- and α2-6-linked sialosides and their use for sialidase substrate specificity studies. Li W, Xiao A, Li Y, Yu H, Chen X Carbohydrate research 28961426 Carbohydr Res 2017 Nov 8
Facile chemoenzymatic synthesis of Lewis a (Le(a)) antigen in gram-scale and sialyl Lewis a (sLe(a)) antigens containing diverse sialic acid forms. Tasnima N, Yu H, Yan X, Li W, Xiao A, Chen X Carbohydrate research 30562693 Carbohydr Res 2019 Jan 15
Streamlined chemoenzymatic total synthesis of prioritized ganglioside cancer antigens. Yu H, Santra A, Li Y, McArthur JB, Ghosh T, Yang X, Wang PG, Chen X Organic & biomolecular chemistry 29789847 Org Biomol Chem 2018 Jun 6
Process Engineering and Glycosyltransferase Improvement for Short Route Chemoenzymatic Total Synthesis of GM1 Gangliosides. Yu H, Zhang L, Yang X, Bai Y, Chen X Chemistry (Weinheim an der Bergstrasse, Germany) 36596720 Chemistry 2023 May 2
Chemoenzymatic Synthesis of N-Acetyl Analogues of 9-O-Acetylated b-Series Gangliosides. Yu H, Zheng Z, Zhang L, Yang X, Varki A, Chen X Tetrahedron 37981995 Tetrahedron 2023 Aug 3
Sialidase-catalyzed one-pot multienzyme (OPME) synthesis of sialidase transition-state analogue inhibitors. Xiao A, Li Y, Li X, Santra A, Yu H, Li W, Chen X ACS catalysis 29713561 ACS Catal 2018 Jan 5
Chemoenzymatic Total Synthesis of GM3 Gangliosides Containing Different Sialic Acid Forms and Various Fatty Acyl Chains. Yu H, Gadi MR, Bai Y, Zhang L, Li L, Yin J, Wang PG, Chen X The Journal of organic chemistry 34152144 J Org Chem 2021 Jul 2
Directed Evolution of Therapeutic Antibodies Targeting Glycosylation in Cancer. Amon R, Rosenfeld R, Perlmutter S, Grant OC, Yehuda S, Borenstein-Katz A, Alcalay R, Marshanski T, Yu H, Diskin R, Woods RJ, Chen X, Padler-Karavani V Cancers 33007970 Cancers (Basel) 2020 Sep 30
Methods for 2-Deoxyglycoside Synthesis. Bennett CS, Galan MC Chemical reviews 29953219 Chem Rev 2018 Sep 12
Versatile Glycosyl Sulfonates in β-Selective C-Glycosylation. Ling J, Bennett CS Angewandte Chemie (International ed. in English) 31880395 Angew Chem Int Ed Engl 2020 Mar 9
Recent Developments in Stereoselective Chemical Glycosylation. Ling J, Bennett CS Asian journal of organic chemistry 31534883 Asian J Org Chem 2019 Jun
An Improved Approach to the Direct Construction of 2-Deoxy-β-Linked Sugars: Applications to Oligosaccharide Synthesis. Lloyd D, Bennett CS Chemistry (Weinheim an der Bergstrasse, Germany) 29572995 Chemistry 2018 May 28
Modular continuous flow synthesis of orthogonally protected 6-deoxy glucose glycals. Yalamanchili S, Nguyen TV, Pohl NLB, Bennett CS Organic & biomolecular chemistry 32293636 Org Biomol Chem 2020 May 6
Automated, Multistep Continuous-Flow Synthesis of 2,6-Dideoxy and 3-Amino-2,3,6-trideoxy Monosaccharide Building Blocks. Yalamanchili S, Nguyen TA, Zsikla A, Stamper G, DeYong AE, Florek J, Vasquez O, Pohl NLB, Bennett CS Angewandte Chemie (International ed. in English) 34463017 Angew Chem Int Ed Engl 2021 Oct 18
Reagent-Controlled α-Selective Dehydrative Glycosylation of 2,6-Dideoxy Sugars: Construction of the Arugomycin Tetrasaccharide. Romeo JR, McDermott L, Bennett CS Organic letters 32281384 Org Lett 2020 May 1
Reagent Controlled Direct Dehydrative Glycosylation with 2-Deoxy Sugars: Construction of the Saquayamycin Z Pentasaccharide. Mizia JC, Bennett CS Organic letters 31305082 Org Lett 2019 Aug 2
Challenges in the Conversion of Manual Processes to Machine-Assisted Syntheses: Activation of Thioglycoside Donors with Aryl(trifluoroethyl)iodonium Triflimide. Saliba RC, Wooke ZJ, Nieves GA, Chu AA, Bennett CS, Pohl NLB Organic letters 29336575 Org Lett 2018 Feb 2
Rapid de Novo Preparation of 2,6-Dideoxy Sugar Libraries through Gold-Catalyzed Homopropargyl Orthoester Cyclization. Yalamanchili S, Miller W, Chen X, Bennett CS Organic letters 31755271 Org Lett 2019 Dec 6
Glycosyl Sulfonates Beyond Triflates. Bennett CS Chemical record (New York, N.Y.) 34142755 Chem Rec 2021 Nov
Matching Glycosyl Donor Reactivity to Sulfonate Leaving Group Ability Permits S(N)2 Glycosylations. Zhuo MH, Wilbur DJ, Kwan EE, Bennett CS Journal of the American Chemical Society 31550879 J Am Chem Soc 2019 Oct 23
Synthesis of the Hexasaccharide Fragment of Landomycin A Using a Mild, Reagent-Controlled Approach. Yalamanchili S, Lloyd D, Bennett CS Organic letters 31021647 Org Lett 2019 May 17
Expanding Glycomic Investigations through Thiol-Derivatized Glycans. Hurst RD, Nieves A, Brichacek M Molecules (Basel, Switzerland) 36838944 Molecules 2023 Feb 18
Transformation of aldehydes into nitriles in an aqueous medium using O-phenylhydroxylamine as the nitrogen source. Cheewawisuttichai T, Hurst RD, Brichacek M Carbohydrate research 33761407 Carbohydr Res 2021 Apr
Development of a multifunctional neoglycoside auxiliary for applications in glycomics research. Cheewawisuttichai T, Brichacek M Organic & biomolecular chemistry 34264248 Org Biomol Chem 2021 Aug 5
Streamlining the chemoenzymatic synthesis of complex N-glycans by a stop and go strategy. Liu L, Prudden AR, Capicciotti CJ, Bosman GP, Yang JY, Chapla DG, Moremen KW, Boons GJ Nature chemistry 30532014 Nat Chem 2019 Feb
Emerging structural insights into glycosyltransferase-mediated synthesis of glycans. Moremen KW, Haltiwanger RS Nature chemical biology 31427814 Nat Chem Biol 2019 Sep
Chemoenzymatic Synthesis of Asymmetrical Multi-Antennary N-Glycans to Dissect Glycan-Mediated Interactions between Human Sperm and Oocytes. Chinoy ZS, Friscourt F, Capicciotti CJ, Chiu P, Boons GJ Chemistry (Weinheim an der Bergstrasse, Germany) 29603480 Chemistry 2018 Jun 4
Glycan remodeled erythrocytes facilitate antigenic characterization of recent A/H3N2 influenza viruses. Broszeit F, van Beek RJ, Unione L, Bestebroer TM, Chapla D, Yang JY, Moremen KW, Herfst S, Fouchier RAM, de Vries RP, Boons GJ Nature communications 34521834 Nat Commun 2021 Sep 14
Improved isolation and characterization procedure of sialylglycopeptide from egg yolk powder. Liu L, Prudden AR, Bosman GP, Boons GJ Carbohydrate research 29096185 Carbohydr Res 2017 Nov 27
An automated platform for the enzyme-mediated assembly of complex oligosaccharides. Li T, Liu L, Wei N, Yang JY, Chapla DG, Moremen KW, Boons GJ Nature chemistry 30792508 Nat Chem 2019 Mar
Chemoenzymatic Synthesis of Campylobacter jejuni Lipo-oligosaccharide Core Domains to Examine Guillain-Barré Syndrome Serum Antibody Specificities. Li T, Wolfert MA, Wei N, Huizinga R, Jacobs BC, Boons GJ Journal of the American Chemical Society 33164488 J Am Chem Soc 2020 Nov 18
Guillain-Barré syndrome: expanding the concept of molecular mimicry. Laman JD, Huizinga R, Boons GJ, Jacobs BC Trends in immunology 35256276 Trends Immunol 2022 Apr
Appropriate aglycone modification significantly expands the glycan substrate acceptability of α1,6-fucosyltransferase (FUT8). Zhang R, Yang Q, Boruah BM, Zong G, Li C, Chapla D, Yang JY, Moremen KW, Wang LX The Biochemical journal 33734311 Biochem J 2021 Apr 30
Chemoenzymatic Tagging of Tn/TF/STF Antigens in Living Systems. Yang Y, Chen M, Wu M, Hong S, Gao B, Liu Y, Yu C, Young TS, Chapla DG, Yang JY, Cappiello JR, Li JP, Sharpless KB, Moremen KW, Wu P Israel journal of chemistry 38737670 Isr J Chem 2023 Oct
Phenanthroline-Catalyzed Stereoselective Formation of α-1,2-cis 2-Deoxy-2-Fluoro Glycosides. DeMent PM, Liu C, Wakpal J, Schaugaard RN, Schlegel HB, Nguyen HM ACS catalysis 34336371 ACS Catal 2021 Feb 19
Enantio- and Diastereoselective Synthesis of Hydroxy Bis(boronates) via Cu-Catalyzed Tandem Borylation/1,2-Addition. Green JC, Joannou MV, Murray SA, Zanghi JM, Meek SJ ACS catalysis 29520326 ACS Catal 2017
Diastereoselective sp(3) C-O Bond Formation via Visible Light-Induced, Copper-Catalyzed Cross-Couplings of Glycosyl Bromides with Aliphatic Alcohols. Yu F, Dickson JL, Loka RS, Xu H, Schaugaard RN, Schlegel HB, Luo L, Nguyen HM ACS catalysis 34168901 ACS Catal 2020 Jun 5
Phenanthroline-Catalyzed Stereoretentive Glycosylations. Yu F, Li J, DeMent PM, Tu YJ, Schlegel HB, Nguyen HM Angewandte Chemie (International ed. in English) 30920099 Angew Chem Int Ed Engl 2019 May 20
Identification of the binding roles of terminal and internal glycan epitopes using enzymatically synthesized N-glycans containing tandem epitopes. Wu Z, Liu Y, Ma C, Li L, Bai J, Byrd-Leotis L, Lasanajak Y, Guo Y, Wen L, Zhu H, Song J, Li Y, Steinhauer DA, Smith DF, Zhao B, Chen X, Guan W, Wang PG Organic & biomolecular chemistry 27752690 Org Biomol Chem 2016 Nov 29
Site-Directed Glycosylation of Peptide/Protein with Homogeneous O-Linked Eukaryotic N-Glycans. Wu Z, Jiang K, Zhu H, Ma C, Yu Z, Li L, Guan W, Liu Y, Zhu H, Chen Y, Li S, Li J, Cheng J, Zhang L, Wang PG Bioconjugate chemistry 27529638 Bioconjug Chem 2016 Sep 21
Chemoenzymatic Synthesis of a Library of Human Milk Oligosaccharides. Xiao Z, Guo Y, Liu Y, Li L, Zhang Q, Wen L, Wang X, Kondengaden SM, Wu Z, Zhou J, Cao X, Li X, Ma C, Wang PG The Journal of organic chemistry 27305319 J Org Chem 2016 Jul 15
A One-Step Chemoenzymatic Labeling Strategy for Probing Sialylated Thomsen-Friedenreich Antigen. Wen L, Liu D, Zheng Y, Huang K, Cao X, Song J, Wang PG ACS central science 29721527 ACS Cent Sci 2018 Apr 25
Facile Chemoenzymatic Synthesis of O-Mannosyl Glycans. Wang S, Zhang Q, Chen C, Guo Y, Gadi MR, Yu J, Westerlind U, Liu Y, Cao X, Wang PG, Li L Angewandte Chemie (International ed. in English) 29732660 Angew Chem Int Ed Engl 2018 Jul 20
Sialic acid linkage-specific permethylation for improved profiling of protein glycosylation by MALDI-TOF MS. Jiang K, Zhu H, Li L, Guo Y, Gashash E, Ma C, Sun X, Li J, Zhang L, Wang PG Analytica chimica acta 28693729 Anal Chim Acta 2017 Aug 15
Chemoenzymatic modular assembly of O-GalNAc glycans for functional glycomics. Wang S, Chen C, Gadi MR, Saikam V, Liu D, Zhu H, Bollag R, Liu K, Chen X, Wang F, Wang PG, Ling P, Guan W, Li L Nature communications 34117223 Nat Commun 2021 Jun 11
Identifying Sialylation Linkages at the Glycopeptide Level by Glycosyltransferase Labeling Assisted Mass Spectrometry (GLAMS). Zhu H, Wang S, Liu D, Ding L, Chen C, Liu Y, Wu Z, Bollag R, Liu K, Alexander WM, Yin J, Ma C, Li L, Wang PG Analytical chemistry 32271005 Anal Chem 2020 May 5
Machine-Driven Chemoenzymatic Synthesis of Glycopeptide. Zhang J, Liu D, Saikam V, Gadi MR, Gibbons C, Fu X, Song H, Yu J, Kondengaden SM, Wang PG, Wen L Angewandte Chemie (International ed. in English) 32677091 Angew Chem Int Ed Engl 2020 Nov 2
Biochemical characterization of an α1,2-colitosyltransferase from Escherichia coli O55:H7. Wu Z, Zhao G, Li T, Qu J, Guan W, Wang J, Ma C, Li X, Zhao W, Wang PG, Li L Glycobiology 26703456 Glycobiology 2016 May
An OGA-Resistant Probe Allows Specific Visualization and Accurate Identification of O-GlcNAc-Modified Proteins in Cells. Li J, Wang J, Wen L, Zhu H, Li S, Huang K, Jiang K, Li X, Ma C, Qu J, Parameswaran A, Song J, Zhao W, Wang PG ACS chemical biology 27622469 ACS Chem Biol 2016 Nov 18
Microarray analyses of closely related glycoforms reveal different accessibilities of glycan determinants on N-glycan branches. Li L, Guan W, Zhang G, Wu Z, Yu H, Chen X, Wang PG Glycobiology 32026940 Glycobiology 2020 Apr 20
Decoding glycan protein interactions by a new class of asymmetric N-glycans. Wu Z, Liu Y, Li L, Wan XF, Zhu H, Guo Y, Wei M, Guan W, Wang PG Organic & biomolecular chemistry 29043371 Org Biomol Chem 2017 Oct 31
Chemoenzymatic synthesis of the bacterial polysaccharide repeating unit undecaprenyl pyrophosphate and its analogs. Li L, Woodward RL, Han W, Qu J, Song J, Ma C, Wang PG Nature protocols 27336706 Nat Protoc 2016 Jul
Machine-Driven Enzymatic Oligosaccharide Synthesis by Using a Peptide Synthesizer. Zhang J, Chen C, Gadi MR, Gibbons C, Guo Y, Cao X, Edmunds G, Wang S, Liu D, Yu J, Wen L, Wang PG Angewandte Chemie (International ed. in English) 30375138 Angew Chem Int Ed Engl 2018 Dec 17
Toward Automated Enzymatic Synthesis of Oligosaccharides. Wen L, Edmunds G, Gibbons C, Zhang J, Gadi MR, Zhu H, Fang J, Liu X, Kong Y, Wang PG Chemical reviews 30011195 Chem Rev 2018 Sep 12
Substrate specificity of FUT8 and chemoenzymatic synthesis of core-fucosylated asymmetric N-glycans. Calderon AD, Liu Y, Li X, Wang X, Chen X, Li L, Wang PG Organic & biomolecular chemistry 27080952 Org Biomol Chem 2016 Apr 26
Natural Product Micheliolide (MCL) Irreversibly Activates Pyruvate Kinase M2 and Suppresses Leukemia. Li J, Li S, Guo J, Li Q, Long J, Ma C, Ding Y, Yan C, Li L, Wu Z, Zhu H, Li KK, Wen L, Zhang Q, Xue Q, Zhao C, Liu N, Ivanov I, Luo M, Xi R, Long H, Wang PG, Chen Y Journal of medicinal chemistry 29641204 J Med Chem 2018 May 10
An enzymatic strategy to asymmetrically branched N-glycans. Calderon AD, Zhou J, Guan W, Wu Z, Guo Y, Bai J, Li Q, Wang PG, Fang J, Li L Organic & biomolecular chemistry 28832049 Org Biomol Chem 2017 Sep 13
N-Linked Glycosylation Prevents Deamidation of Glycopeptide and Glycoprotein. Zhu HJ, Liu D, Tran VP, Wu Z, Jiang K, Zhu H, Zhang J, Gibbons C, Xue B, Shi H, Wang PG ACS chemical biology 33270417 ACS Chem Biol 2020 Dec 18
Synthesis of Chondroitin Sulfate A Bearing Syndecan-1 Glycopeptide. Ramadan S, Yang W, Zhang Z, Huang X Organic letters 28849661 Org Lett 2017 Sep 15
Preactivation-based chemoselective glycosylations: A powerful strategy for oligosaccharide assembly. Yang W, Yang B, Ramadan S, Huang X Beilstein journal of organic chemistry 29062430 Beilstein J Org Chem 2017
Synthetic oligosaccharides can replace animal-sourced low-molecular weight heparins. Xu Y, Chandarajoti K, Zhang X, Pagadala V, Dou W, Hoppensteadt DM, Sparkenbaugh EM, Cooley B, Daily S, Key NS, Severynse-Stevens D, Fareed J, Linhardt RJ, Pawlinski R, Liu J Science translational medicine 28878012 Sci Transl Med 2017 Sep 6
Obstacles and solutions for chemical synthesis of syndecan-3 (53-62) glycopeptides with two heparan sulfate chains. Yang W, Yoshida K, Yang B, Huang X Carbohydrate research 27810711 Carbohydr Res 2016 Nov 29
Homoserine as an Aspartic Acid Precursor for Synthesis of Proteoglycan Glycopeptide Containing Aspartic Acid and a Sulfated Glycan Chain. Yang W, Ramadan S, Yang B, Yoshida K, Huang X The Journal of organic chemistry 27809505 J Org Chem 2016 Dec 2
Binding and neurotoxicity mitigation of toxic tau oligomers by synthetic heparin like oligosaccharides. Wang P , Lo Cascio F , Gao J , Kayed R , Huang X Chemical communications (Cambridge, England) 30128457 Chem Commun (Camb) 2018 Sep 6
Expedient Synthesis of Core Disaccharide Building Blocks from Natural Polysaccharides for Heparan Sulfate Oligosaccharide Assembly. Pawar NJ, Wang L, Higo T, Bhattacharya C, Kancharla PK, Zhang F, Baryal K, Huo CX, Liu J, Linhardt RJ, Huang X, Hsieh-Wilson LC Angewandte Chemie (International ed. in English) 31553820 Angew Chem Int Ed Engl 2019 Dec 16
Tools for mammalian glycoscience research. Griffin ME, Hsieh-Wilson LC Cell 35809571 Cell 2022 Jul 21
Synthesis of a Systematic 64-Membered Heparan Sulfate Tetrasaccharide Library. Baryal KN, Ramadan S, Su G, Huo C, Zhao Y, Liu J, Hsieh-Wilson LC, Huang X Angewandte Chemie (International ed. in English) 36173931 Angew Chem Int Ed Engl 2023 Jan 2
Automated Solid Phase Assisted Synthesis of a Heparan Sulfate Disaccharide Library. Ramadan S, Su G, Baryal K, Hsieh-Wilson LC, Liu J, Huang X Organic chemistry frontiers : an international journal of organic chemistry 36212917 Org Chem Front 2022 Jun 7
Recent advances in the synthesis of extensive libraries of heparan sulfate oligosaccharides for structure-activity relationship studies. Ramadan S, Mayieka M, Pohl NLB, Liu J, Hsieh-Wilson LC, Huang X Current opinion in chemical biology 38636446 Curr Opin Chem Biol 2024 Jun
Divergent Synthesis of Heparan Sulfate Oligosaccharides. Dulaney SB, Xu Y, Wang P, Tiruchinapally G, Wang Z, Kathawa J, El-Dakdouki MH, Yang B, Liu J, Huang X The Journal of organic chemistry 26574650 J Org Chem 2015 Dec 18
Synthesis of 3-O-Sulfated Oligosaccharides to Understand the Relationship between Structures and Functions of Heparan Sulfate. Wang Z, Hsieh PH, Xu Y, Thieker D, Chai EJE, Xie S, Cooley B, Woods RJ, Chi L, Liu J Journal of the American Chemical Society 28340300 J Am Chem Soc 2017 Apr 12
Expedient Synthesis of a Library of Heparan Sulfate-Like "Head-to-Tail" Linked Multimers for Structure and Activity Relationship Studies. Zhang J, Liang L, Yang W, Ramadan S, Baryal K, Huo CX, Bernard JJ, Liu J, Hsieh-Wilson L, Zhang F, Linhardt RJ, Huang X Angewandte Chemie (International ed. in English) 36199167 Angew Chem Int Ed Engl 2022 Nov 25
Efficient platform for synthesizing comprehensive heparan sulfate oligosaccharide libraries for decoding glycosaminoglycan-protein interactions. Wang L, Sorum AW, Huang BS, Kern MK, Su G, Pawar N, Huang X, Liu J, Pohl NLB, Hsieh-Wilson LC Nature chemistry 37349377 Nat Chem 2023 Aug
Sensitive and robust MALDI-TOF-MS glycomics analysis enabled by Girard's reagent T on-target derivatization (GTOD) of reducing glycans. Zhang Y, Wang B, Jin W, Wen Y, Nan L, Yang M, Liu R, Zhu Y, Wang C, Huang L, Song X, Wang Z Analytica chimica acta 30598139 Anal Chim Acta 2019 Feb 7
Large scale preparation of high mannose and paucimannose N-glycans from soybean proteins by oxidative release of natural glycans (ORNG). Zhu Y, Yan M, Lasanajak Y, Smith DF, Song X Carbohydrate research 29803109 Carbohydr Res 2018 Jul 15
Oxidative release of natural glycans for functional glycomics. Song X, Ju H, Lasanajak Y, Kudelka MR, Smith DF, Cummings RD Nature methods 27135973 Nat Methods 2016 Jun
Preparation of Complex Glycans From Natural Sources for Functional Study. Zhang Q, Li Z, Song X Frontiers in chemistry 32719769 Front Chem 2020
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GlycoFibroTyper: A Novel Method for the Glycan Analysis of IgG and the Development of a Biomarker Signature of Liver Fibrosis. Scott DA, Wang M, Grauzam S, Pippin S, Black A, Angel PM, Drake RR, Castellino S, Kono Y, Rockey DC, Mehta AS Frontiers in immunology 35197973 Front Immunol 2022
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Development of an Antibody-Based Platform for the Analysis of Immune Cell-Specific N-linked Glycosylation. Dressman JW, McDowell CT, Lu X, Angel PM, Drake RR, Mehta AS Analytical chemistry 37293957 Anal Chem 2023 Jul 11
Utilizing multimodal mass spectrometry imaging for profiling immune cell composition and N-glycosylation across colorectal carcinoma disease progression. Young LEA, Nietert PJ, Stubler R, Kittrell CG, Grimsley G, Lewin DN, Mehta AS, Hajar C, Wang K, O'Quinn EC, Angel PM, Wallace K, Drake RR Frontiers in pharmacology 38273829 Front Pharmacol 2023
On the Cutting Edge of Translational Research. Angel PM Clinical chemistry 33230521 Clin Chem 2021 Mar 31
Multiplexed imaging mass spectrometry of the extracellular matrix using serial enzyme digests from formalin-fixed paraffin-embedded tissue sections. Clift CL, Drake RR, Mehta A, Angel PM Analytical and bioanalytical chemistry 33206215 Anal Bioanal Chem 2021 Apr
Antibody Panel Based N-Glycan Imaging for N-Glycoprotein Biomarker Discovery. Black AP, Angel PM, Drake RR, Mehta AS Current protocols in protein science 31721442 Curr Protoc Protein Sci 2019 Dec
Spatial N-glycomics of the human aortic valve in development and pediatric endstage congenital aortic valve stenosis. Angel PM, Drake RR, Park Y, Clift CL, West C, Berkhiser S, Hardiman G, Mehta AS, Bichell DP, Su YR Journal of molecular and cellular cardiology 33516683 J Mol Cell Cardiol 2021 May
Imaging Mass Spectrometry and Lectin Analysis of N-Linked Glycans in Carbohydrate Antigen-Defined Pancreatic Cancer Tissues. McDowell CT, Klamer Z, Hall J, West CA, Wisniewski L, Powers TW, Angel PM, Mehta AS, Lewin DN, Haab BB, Drake RR Molecular & cellular proteomics : MCP 33581409 Mol Cell Proteomics 2021
Applications and continued evolution of glycan imaging mass spectrometry. McDowell CT, Lu X, Mehta AS, Angel PM, Drake RR Mass spectrometry reviews 34392557 Mass Spectrom Rev 2023 Mar
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Set Up for Failure: Pre-Existing Autoantibodies in Lung Transplant. McQuiston A, Emtiazjoo A, Angel P, Machuca T, Christie J, Atkinson C Frontiers in immunology 34456920 Front Immunol 2021
Rapid N-Glycan Profiling of Serum and Plasma by a Novel Slide-Based Imaging Mass Spectrometry Workflow. Blaschke CRK, Black AP, Mehta AS, Angel PM, Drake RR Journal of the American Society for Mass Spectrometry 32809822 J Am Soc Mass Spectrom 2020 Dec 2
Array-Based N-Glycan Profiling of Cells in Culture. Angel PM, Mehta AS, Drake RR Methods in molecular biology (Clifton, N.J.) 33908018 Methods Mol Biol 2021
Collagen fiber regulation in human pediatric aortic valve development and disease. Clift CL, Su YR, Bichell D, Jensen Smith HC, Bethard JR, Norris-Caneda K, Comte-Walters S, Ball LE, Hollingsworth MA, Mehta AS, Drake RR, Angel PM Scientific reports 33963260 Sci Rep 2021 May 7
The role of neuraminidase in TLR4-MAPK signalling and the release of cytokines by lupus serum-stimulated mesangial cells. Sundararaj K, Rodgers J, Angel P, Wolf B, Nowling TK Immunology 33314123 Immunology 2021 Apr
Optimization of Multiple Glycosidase and Chemical Stabilization Strategies for N-Glycan Isomer Detection by Mass Spectrometry Imaging in Formalin-Fixed, Paraffin-Embedded Tissues. West CA, Lu X, Grimsley G, Norris-Caneda K, Mehta AS, Angel PM, Drake RR Methods in molecular biology (Clifton, N.J.) 33908016 Methods Mol Biol 2021
Bioorthogonal Chemical Labeling Probes Targeting Sialic Acid Isomers for N-Glycan MALDI Imaging Mass Spectrometry of Tissues, Cells, and Biofluids. Lu X, McDowell CT, Blaschke CRK, Liu L, Grimsley G, Wisniewski L, Gao C, Mehta AS, Haab BB, Angel PM, Drake RR Analytical chemistry 37126482 Anal Chem 2023 May 16
An N-glycome tissue atlas of 15 human normal and cancer tissue types determined by MALDI-imaging mass spectrometry. Wallace EN, West CA, McDowell CT, Lu X, Bruner E, Mehta AS, Aoki-Kinoshita KF, Angel PM, Drake RR Scientific reports 38177192 Sci Rep 2024 Jan 4
Pro-inflammatory IgG1 N-glycan signature correlates with primary graft dysfunction onset in COPD patients. McQuiston A, Scott D, Nord D, Langerude L, Pelaez A, Machuca T, Mehta A, Drake RR, Christie JD, Angel P, Atkinson C Transplant immunology 34767945 Transpl Immunol 2022 Apr
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Integrating age, BMI, and serum N-glycans detected by MALDI mass spectrometry to classify suspicious mammogram findings as benign lesions or breast cancer. Blaschke CRK, Hill EG, Mehta AS, Angel PM, Laronga C, Drake RR Scientific reports 36460712 Sci Rep 2022 Dec 2
Evaluation of Therapeutic Collagen-Based Biomaterials in the Infarcted Mouse Heart by Extracellular Matrix Targeted MALDI Imaging Mass Spectrometry. Clift CL, McLaughlin S, Muñoz M, Suuronen EJ, Rotstein BH, Mehta AS, Drake RR, Alarcon EI, Angel PM Journal of the American Society for Mass Spectrometry 34713699 J Am Soc Mass Spectrom 2021 Dec 1
Glycan Imaging Mass Spectrometry: Progress in Developing Clinical Diagnostic Assays for Tissues, Biofluids, and Cells. Blaschke CRK, McDowell CT, Black AP, Mehta AS, Angel PM, Drake RR Clinics in laboratory medicine 34020762 Clin Lab Med 2021 Jun
Metabolic Markers and Association of Biological Sex in Lupus Nephritis. Wolf B, Blaschke CRK, Mungaray S, Weselman BT, Stefanenko M, Fedoriuk M, Bai H, Rodgers J, Palygin O, Drake RR, Nowling TK International journal of molecular sciences 38003679 Int J Mol Sci 2023 Nov 18
Determining the N-Glycan and Collagen/Extracellular Matrix Protein Compositions in a Novel Outcome Cohort of Prostate Cancer Tissue Microarrays Using MALDI-MSI. Hartig JP, Bejar K, Young LEA, Grimsley G, Bethard JR, Troyer DA, Hernandez J, Wu JD, Ippolito JE, Ball LE, Gelfond JAL, Johnson-Pais TL, Mehta AS, Leach RJ, Angel PM, Drake RR Cancer research communications 39347566 Cancer Res Commun 2024 Nov 1
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A glycan-based approach to cell characterization and isolation: Hematopoiesis as a paradigm. Piszczatowski RT, Schwenger E, Sundaravel S, Stein CM, Liu Y, Stanley P, Verma A, Zheng D, Seidel RD, Almo SC, Townley RA, Bülow HE, Steidl U The Journal of experimental medicine 36066492 J Exp Med 2022 Nov 7
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Combinatorial Virtual Library Screening Study of Transforming Growth Factor-β2-Chondroitin Sulfate System. Sankaranarayanan NV, Nagarajan B, Desai UR International journal of molecular sciences 34299163 Int J Mol Sci 2021 Jul 14
Molecular dynamics simulations to understand glycosaminoglycan interactions in the free- and protein-bound states. Nagarajan B, Holmes SG, Sankaranarayanan NV, Desai UR Current opinion in structural biology 35306321 Curr Opin Struct Biol 2022 Jun
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Merging cultures and disciplines to create a drug discovery ecosystem at Virginia commonwealth university: Medicinal chemistry, structural biology, molecular and behavioral pharmacology and computational chemistry. Kellogg GE, Cen Y, Dukat M, Ellis KC, Guo Y, Li J, May AE, Safo MK, Zhang S, Zhang Y, Desai UR SLAS discovery : advancing life sciences R & D 36863508 SLAS Discov 2023 Sep
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In-Depth Molecular Dynamics Study of All Possible Chondroitin Sulfate Disaccharides Reveals Key Insight into Structural Heterogeneity and Dynamism. Nagarajan B, Sankaranarayanan NV, Desai UR Biomolecules 35053225 Biomolecules 2022 Jan 5
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Discovery of Sulfated Small Molecule Inhibitors of Matrix Metalloproteinase-8. Morla S, Desai UR Biomolecules 32784891 Biomolecules 2020 Aug 9
Design and Synthesis of Small Molecule Probes of MDA-9/Syntenin. Sankaranarayanan NV, Villuri BK, Nagarajan B, Lewicki S, Das SK, Fisher PB, Desai UR Biomolecules 39456220 Biomolecules 2024 Oct 12
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Nanosecond photochemically promoted click chemistry for enhanced neuropeptide visualization and rapid protein labeling. Li G, Ma F, Cao Q, Zheng Z, DeLaney K, Liu R, Li L Nature communications 31619683 Nat Commun 2019 Oct 16
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In-Depth Site-Specific O-Glycosylation Analysis of Glycoproteins and Endogenous Peptides in Cerebrospinal Fluid (CSF) from Healthy Individuals, Mild Cognitive Impairment (MCI), and Alzheimer's Disease (AD) Patients. Chen Z, Wang D, Yu Q, Johnson J, Shipman R, Zhong X, Huang J, Yu Q, Zetterberg H, Asthana S, Carlsson C, Okonkwo O, Li L ACS chemical biology 34964596 ACS Chem Biol 2022 Nov 18
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Developing mass spectrometry for the quantitative analysis of neuropeptides. Sauer CS, Phetsanthad A, Riusech OL, Li L Expert review of proteomics 34375152 Expert Rev Proteomics 2021 Jul
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Identification of Double Bond Position Isomers in Unsaturated Lipids by m-CPBA Epoxidation and Mass Spectrometry Fragmentation. Feng Y, Chen B, Yu Q, Li L Analytical chemistry 30608661 Anal Chem 2019 Feb 5
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Comparison of the Interactions of Different Growth Factors and Glycosaminoglycans. Zhang F, Zheng L, Cheng S, Peng Y, Fu L, Zhang X, Linhardt RJ Molecules (Basel, Switzerland) 31527407 Molecules 2019 Sep 16
Bottom-up and top-down profiling of pentosan polysulfate. Lin L , Yu Y , Zhang F , Xia K , Zhang X , Linhardt RJ The Analyst 31287456 Analyst 2019 Aug 5
Structural characterization of a clinically described heparin-like substance in plasma causing bleeding. Yu Y, Bruzdoski K, Kostousov V, Hensch L, Hui SK, Siddiqui F, Farooqui A, Kouta A, Zhang F, Fareed J, Teruya J, Linhardt RJ Carbohydrate polymers 32536393 Carbohydr Polym 2020 Sep 15
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Fluorescent Trimeric Hemagglutinins Reveal Multivalent Receptor Binding Properties. Nemanichvili N, Tomris I, Turner HL, McBride R, Grant OC, van der Woude R, Aldosari MH, Pieters RJ, Woods RJ, Paulson JC, Boons GJ, Ward AB, Verheije MH, de Vries RP Journal of molecular biology 30597163 J Mol Biol 2019 Feb 15
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