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The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.
Title | Author | Journal Name | PubMedID | Journal Abbreviation | Publication Date |
---|---|---|---|---|---|
Metabolic plasticity drives development during mammalian embryogenesis. | Sharpley MS, Chi F, Hoeve JT, Banerjee U | Developmental cell | 34428399 | Dev Cell | 2021 Aug 23 |
Glycolysis-Independent Glucose Metabolism Distinguishes TE from ICM Fate during Mammalian Embryogenesis. | Chi F, Sharpley MS, Nagaraj R, Roy SS, Banerjee U | Developmental cell | 32197068 | Dev Cell | 2020 Apr 6 |
Regulated noise in the epigenetic landscape of development and disease. | Pujadas E, Feinberg AP | Cell | 22424224 | Cell | 2012 Mar 16 |
Reversible switching between epigenetic states in honeybee behavioral subcastes. | Herb BR, Wolschin F, Hansen KD, Aryee MJ, Langmead B, Irizarry R, Amdam GV, Feinberg AP | Nature neuroscience | 22983211 | Nat Neurosci | 2012 Oct |
The evolution of bacterial mechanosensitive channels. | Booth IR, Miller S, Müller A, Lehtovirta-Morley L | Cell calcium | 25591932 | Cell Calcium | 2015 Mar |
The glove-like structure of the conserved membrane protein TatC provides insight into signal sequence recognition in twin-arginine translocation. | Ramasamy S, Abrol R, Suloway CJ, Clemons WM Jr | Structure (London, England : 1993) | 23583035 | Structure | 2013 May 7 |
Minimal requirements for inhibition of MraY by lysis protein E from bacteriophage ΦX174. | Tanaka S, Clemons WM Jr | Molecular microbiology | 22742425 | Mol Microbiol | 2012 Sep |
Pupil fluctuations track rapid changes in adrenergic and cholinergic activity in cortex. | Reimer J, McGinley MJ, Liu Y, Rodenkirch C, Wang Q, McCormick DA, Tolias AS | Nature communications | 27824036 | Nat Commun | 2016 Nov 8 |
Benchmarking Spike Rate Inference in Population Calcium Imaging. | Theis L, Berens P, Froudarakis E, Reimer J, Román Rosón M, Baden T, Euler T, Tolias AS, Bethge M | Neuron | 27151639 | Neuron | 2016 May 4 |
Pupil fluctuations track fast switching of cortical states during quiet wakefulness. | Reimer J, Froudarakis E, Cadwell CR, Yatsenko D, Denfield GH, Tolias AS | Neuron | 25374359 | Neuron | 2014 Oct 22 |
Deep convolutional models improve predictions of macaque V1 responses to natural images. | Cadena SA, Denfield GH, Walker EY, Gatys LA, Tolias AS, Bethge M, Ecker AS | PLoS computational biology | 31013278 | PLoS Comput Biol | 2019 Apr |
Principles of connectivity among morphologically defined cell types in adult neocortex. | Jiang X, Shen S, Cadwell CR, Berens P, Sinz F, Ecker AS, Patel S, Tolias AS | Science (New York, N.Y.) | 26612957 | Science | 2015 Nov 27 |
Electrophysiological, transcriptomic and morphologic profiling of single neurons using Patch-seq. | Cadwell CR, Palasantza A, Jiang X, Berens P, Deng Q, Yilmaz M, Reimer J, Shen S, Bethge M, Tolias KF, Sandberg R, Tolias AS | Nature biotechnology | 26689543 | Nat Biotechnol | 2016 Feb |
Waking State: Rapid Variations Modulate Neural and Behavioral Responses. | McGinley MJ, Vinck M, Reimer J, Batista-Brito R, Zagha E, Cadwell CR, Tolias AS, Cardin JA, McCormick DA | Neuron | 26402600 | Neuron | 2015 Sep 23 |
Improved estimation and interpretation of correlations in neural circuits. | Yatsenko D, Josić K, Ecker AS, Froudarakis E, Cotton RJ, Tolias AS | PLoS computational biology | 25826696 | PLoS Comput Biol | 2015 Mar |
Attentional fluctuations induce shared variability in macaque primary visual cortex. | Denfield GH, Ecker AS, Shinn TJ, Bethge M, Tolias AS | Nature communications | 29985411 | Nat Commun | 2018 Jul 9 |
Learning divisive normalization in primary visual cortex. | Burg MF, Cadena SA, Denfield GH, Walker EY, Tolias AS, Bethge M, Ecker AS | PLoS computational biology | 34097695 | PLoS Comput Biol | 2021 Jun |
Population code in mouse V1 facilitates readout of natural scenes through increased sparseness. | Froudarakis E, Berens P, Ecker AS, Cotton RJ, Sinz FH, Yatsenko D, Saggau P, Bethge M, Tolias AS | Nature neuroscience | 24747577 | Nat Neurosci | 2014 Jun |
On the Structure of Neuronal Population Activity under Fluctuations in Attentional State. | Ecker AS, Denfield GH, Bethge M, Tolias AS | The Journal of neuroscience : the official journal of the Society for Neuroscience | 26843656 | J Neurosci | 2016 Feb 3 |
Multimodal profiling of single-cell morphology, electrophysiology, and gene expression using Patch-seq. | Cadwell CR, Scala F, Li S, Livrizzi G, Shen S, Sandberg R, Jiang X, Tolias AS | Nature protocols | 29189773 | Nat Protoc | 2017 Dec |
Cell type composition and circuit organization of clonally related excitatory neurons in the juvenile mouse neocortex. | Cadwell CR, Scala F, Fahey PG, Kobak D, Mulherkar S, Sinz FH, Papadopoulos S, Tan ZH, Johnsson P, Hartmanis L, Li S, Cotton RJ, Tolias KF, Sandberg R, Berens P, Jiang X, Tolias AS | eLife | 32134385 | Elife | 2020 Mar 5 |
Gene delivery to the retina: from mouse to man. | Bennett J, Chung DC, Maguire A | Methods in enzymology | 22365778 | Methods Enzymol | 2012 |
A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear. | Landegger LD, Pan B, Askew C, Wassmer SJ, Gluck SD, Galvin A, Taylor R, Forge A, Stankovic KM, Holt JR, Vandenberghe LH | Nature biotechnology | 28165475 | Nat Biotechnol | 2017 Mar |
Basal exon skipping and genetic pleiotropy: A predictive model of disease pathogenesis. | Drivas TG, Wojno AP, Tucker BA, Stone EM, Bennett J | Science translational medicine | 26062849 | Sci Transl Med | 2015 Jun 10 |
Promising and delivering gene therapies for vision loss. | Carvalho LS, Vandenberghe LH | Vision research | 25094052 | Vision Res | 2015 Jun |
What Is Next for Retinal Gene Therapy? | Vandenberghe LH | Cold Spring Harbor perspectives in medicine | 25877395 | Cold Spring Harb Perspect Med | 2015 Apr 15 |
Efficient transduction and optogenetic stimulation of retinal bipolar cells by a synthetic adeno-associated virus capsid and promoter. | Cronin T, Vandenberghe LH, Hantz P, Juttner J, Reimann A, Kacsó AE, Huckfeldt RM, Busskamp V, Kohler H, Lagali PS, Roska B, Bennett J | EMBO molecular medicine | 25092770 | EMBO Mol Med | 2014 Sep |
Perspectives on best practices for gene therapy programs. | Cheever TR, Berkley D, Braun S, Brown RH, Byrne BJ, Chamberlain JS, Cwik V, Duan D, Federoff HJ, High KA, Kaspar BK, Klinger KW, Larkindale J, Lincecum J, Mavilio F, McDonald CL, McLaughlin J, Weiss McLeod B, Mendell JR, Nuckolls G, Stedman HH, Tagle DA, Vandenberghe LH, Wang H, Wernett PJ, Wilson JM, Porter JD, Gubitz AK | Human gene therapy | 25654329 | Hum Gene Ther | 2015 Mar |
In vitro and in vivo rescue of aberrant splicing in CEP290-associated LCA by antisense oligonucleotide delivery. | Garanto A, Chung DC, Duijkers L, Corral-Serrano JC, Messchaert M, Xiao R, Bennett J, Vandenberghe LH, Collin RW | Human molecular genetics | 27106101 | Hum Mol Genet | 2016 Jun 15 |
The Assembly-Activating Protein Promotes Stability and Interactions between AAV's Viral Proteins to Nucleate Capsid Assembly. | Maurer AC, Pacouret S, Cepeda Diaz AK, Blake J, Andres-Mateos E, Vandenberghe LH | Cell reports | 29742436 | Cell Rep | 2018 May 8 |
Adeno-associated virus: fit to serve. | Zinn E, Vandenberghe LH | Current opinion in virology | 25128609 | Curr Opin Virol | 2014 Oct |
AAV9 targets cone photoreceptors in the nonhuman primate retina. | Vandenberghe LH, Bell P, Maguire AM, Xiao R, Hopkins TB, Grant R, Bennett J, Wilson JM | PloS one | 23382846 | PLoS One | 2013 |
Retinal gene therapy coming of age. | Cepko CL, Vandenberghe LH | Human gene therapy | 23458444 | Hum Gene Ther | 2013 Mar |
Controlling AAV Tropism in the Nervous System with Natural and Engineered Capsids. | Castle MJ, Turunen HT, Vandenberghe LH, Wolfe JH | Methods in molecular biology (Clifton, N.J.) | 26611584 | Methods Mol Biol | 2016 |
In Silico Reconstruction of the Viral Evolutionary Lineage Yields a Potent Gene Therapy Vector. | Zinn E, Pacouret S, Khaychuk V, Turunen HT, Carvalho LS, Andres-Mateos E, Shah S, Shelke R, Maurer AC, Plovie E, Xiao R, Vandenberghe LH | Cell reports | 26235624 | Cell Rep | 2015 Aug 11 |
Restoration of Vision and Retinal Responses After Adeno-Associated Virus-Mediated Optogenetic Therapy in Blind Dogs. | Nikonov S, Aravand P, Lyubarsky A, Nikonov R, Luo AJ, Wei Z, Maguire AM, Phelps NT, Shpylchak I, Willett K, Aleman TS, Huckfeldt RM, Ramachandran PS, Bennett J | Translational vision science & technology | 35604672 | Transl Vis Sci Technol | 2022 May 2 |
Membrane Potential Dynamics of CA1 Pyramidal Neurons during Hippocampal Ripples in Awake Mice. | Hulse BK, Moreaux LC, Lubenov EV, Siapas AG | Neuron | 26889811 | Neuron | 2016 Feb 17 |
Structured Variability in Purkinje Cell Activity during Locomotion. | Sauerbrei BA, Lubenov EV, Siapas AG | Neuron | 26291165 | Neuron | 2015 Aug 19 |
Model-based spike sorting with a mixture of drifting t-distributions. | Shan KQ, Lubenov EV, Siapas AG | Journal of neuroscience methods | 28652008 | J Neurosci Methods | 2017 Aug 15 |
Brain State Dependence of Hippocampal Subthreshold Activity in Awake Mice. | Hulse BK, Lubenov EV, Siapas AG | Cell reports | 28052244 | Cell Rep | 2017 Jan 3 |
Spatial tuning and brain state account for dorsal hippocampal CA1 activity in a non-spatial learning task. | Shan KQ, Lubenov EV, Papadopoulou M, Siapas AG | eLife | 27487561 | Elife | 2016 Aug 3 |
Nanofabricated Neural Probes for Dense 3-D Recordings of Brain Activity. | Rios G, Lubenov EV, Chi D, Roukes ML, Siapas AG | Nano letters | 27766885 | Nano Lett | 2016 Nov 9 |
Endogenous Retroviral Envelope Syncytin Induces HIV-1 Spreading and Establishes HIV Reservoirs in Placenta. | Tang Y, Woodward BO, Pastor L, George AM, Petrechko O, Nouvet FJ, Haas DW, Jiang G, Hildreth JEK | Cell reports | 32234485 | Cell Rep | 2020 Mar 31 |
Bipolar cell-photoreceptor connectivity in the zebrafish (Danio rerio) retina. | Li YN, Tsujimura T, Kawamura S, Dowling JE | The Journal of comparative neurology | 22907678 | J Comp Neurol | 2012 Nov 1 |
Spinal projection neurons control turning behaviors in zebrafish. | Huang KH, Ahrens MB, Dunn TW, Engert F | Current biology : CB | 23910662 | Curr Biol | 2013 Aug 19 |
Large-scale imaging in small brains. | Ahrens MB, Engert F | Current opinion in neurobiology | 25636154 | Curr Opin Neurobiol | 2015 Jun |
Navigational strategies underlying phototaxis in larval zebrafish. | Chen X, Engert F | Frontiers in systems neuroscience | 24723859 | Front Syst Neurosci | 2014 |
Neural Circuits Underlying Visually Evoked Escapes in Larval Zebrafish. | Dunn TW, Gebhardt C, Naumann EA, Riegler C, Ahrens MB, Engert F, Del Bene F | Neuron | 26804997 | Neuron | 2016 Feb 3 |
Pluripotency factors in embryonic stem cells regulate differentiation into germ layers. | Thomson M, Liu SJ, Zou LN, Smith Z, Meissner A, Ramanathan S | Cell | 21663792 | Cell | 2011 Jun 10 |
A compressed sensing framework for efficient dissection of neural circuits. | Lee JB, Yonar A, Hallacy T, Shen CH, Milloz J, Srinivasan J, Kocabas A, Ramanathan S | Nature methods | 30573831 | Nat Methods | 2019 Jan |
Potential role for snoRNAs in PKR activation during metabolic stress. | Youssef OA, Safran SA, Nakamura T, Nix DA, Hotamisligil GS, Bass BL | Proceedings of the National Academy of Sciences of the United States of America | 25848059 | Proc Natl Acad Sci U S A | 2015 Apr 21 |
Drosophila dicer-2 cleavage is mediated by helicase- and dsRNA termini-dependent states that are modulated by Loquacious-PD. | Sinha NK, Trettin KD, Aruscavage PJ, Bass BL | Molecular cell | 25891075 | Mol Cell | 2015 May 7 |
Identification of the long, edited dsRNAome of LPS-stimulated immune cells. | Blango MG, Bass BL | Genome research | 27197207 | Genome Res | 2016 Jun |
Genome-wide profiling of the C. elegans dsRNAome. | Whipple JM, Youssef OA, Aruscavage PJ, Nix DA, Hong C, Johnson WE, Bass BL | RNA (New York, N.Y.) | 25805852 | RNA | 2015 May |
Genome-wide identification and quantitative analysis of cleaved tRNA fragments induced by cellular stress. | Saikia M, Krokowski D, Guan BJ, Ivanov P, Parisien M, Hu GF, Anderson P, Pan T, Hatzoglou M | The Journal of biological chemistry | 23086926 | J Biol Chem | 2012 Dec 14 |
How the fly balances its ability to combat different pathogens. | Chambers MC, Lightfield KL, Schneider DS | PLoS pathogens | 23271964 | PLoS Pathog | 2012 |
Disease tolerance as a defense strategy. | Medzhitov R, Schneider DS, Soares MP | Science (New York, N.Y.) | 22363001 | Science | 2012 Feb 24 |
Tracing personalized health curves during infections. | Schneider DS | PLoS biology | 21957398 | PLoS Biol | 2011 Sep |
Tolerance of infections. | Ayres JS, Schneider DS | Annual review of immunology | 22224770 | Annu Rev Immunol | 2012 |
Guided Homing of Cells in Multi-Photon Microfabricated Bioscaffolds. | Skylar-Scott MA, Liu MC, Wu Y, Dixit A, Yanik MF | Advanced healthcare materials | 27059425 | Adv Healthc Mater | 2016 May |
Cholinergic Signaling Controls Conditioned Fear Behaviors and Enhances Plasticity of Cortical-Amygdala Circuits. | Jiang L, Kundu S, Lederman JD, López-Hernández GY, Ballinger EC, Wang S, Talmage DA, Role LW | Neuron | 27161525 | Neuron | 2016 Jun 1 |
Electrophysiological properties of basal forebrain cholinergic neurons identified by genetic and optogenetic tagging. | López-Hernández GY, Ananth M, Jiang L, Ballinger EC, Talmage DA, Role LW | Journal of neurochemistry | 28791701 | J Neurochem | 2017 Aug |
Targeted gene knockout by direct delivery of zinc-finger nuclease proteins. | Gaj T, Guo J, Kato Y, Sirk SJ, Barbas CF 3rd | Nature methods | 22751204 | Nat Methods | 2012 Jul 1 |
Structural characterization of anti-inflammatory immunoglobulin G Fc proteins. | Ahmed AA, Giddens J, Pincetic A, Lomino JV, Ravetch JV, Wang LX, Bjorkman PJ | Journal of molecular biology | 25036289 | J Mol Biol | 2014 Sep 9 |
Intra-spike crosslinking overcomes antibody evasion by HIV-1. | Galimidi RP, Klein JS, Politzer MS, Bai S, Seaman MS, Nussenzweig MC, West AP Jr, Bjorkman PJ | Cell | 25635457 | Cell | 2015 Jan 29 |
Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues. | West AP Jr, Scharf L, Horwitz J, Klein F, Nussenzweig MC, Bjorkman PJ | Proceedings of the National Academy of Sciences of the United States of America | 23754383 | Proc Natl Acad Sci U S A | 2013 Jun 25 |
Antibody engineering for increased potency, breadth and half-life. | Sievers SA, Scharf L, West AP Jr, Bjorkman PJ | Current opinion in HIV and AIDS | 25760931 | Curr Opin HIV AIDS | 2015 May |
Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120. | West AP Jr, Diskin R, Nussenzweig MC, Bjorkman PJ | Proceedings of the National Academy of Sciences of the United States of America | 22745174 | Proc Natl Acad Sci U S A | 2012 Jul 24 |
Design and characterization of structured protein linkers with differing flexibilities. | Klein JS, Jiang S, Galimidi RP, Keeffe JR, Bjorkman PJ | Protein engineering, design & selection : PEDS | 25301959 | Protein Eng Des Sel | 2014 Oct |
Structural insights on the role of antibodies in HIV-1 vaccine and therapy. | West AP Jr, Scharf L, Scheid JF, Klein F, Bjorkman PJ, Nussenzweig MC | Cell | 24529371 | Cell | 2014 Feb 13 |
Discovery of small molecules that bind to K-Ras and inhibit Sos-mediated activation. | Sun Q, Burke JP, Phan J, Burns MC, Olejniczak ET, Waterson AG, Lee T, Rossanese OW, Fesik SW | Angewandte Chemie (International ed. in English) | 22566140 | Angew Chem Int Ed Engl | 2012 Jun 18 |
A high-throughput fluorescence polarization anisotropy assay for the 70N domain of replication protein A. | Souza-Fagundes EM, Frank AO, Feldkamp MD, Dorset DC, Chazin WJ, Rossanese OW, Olejniczak ET, Fesik SW | Analytical biochemistry | 22197419 | Anal Biochem | 2012 Feb 15 |
Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS. | Abbott JR, Patel PA, Howes JE, Akan DT, Kennedy JP, Burns MC, Browning CF, Sun Q, Rossanese OW, Phan J, Waterson AG, Fesik SW | ACS medicinal chemistry letters | 30258545 | ACS Med Chem Lett | 2018 Sep 13 |
Discovery of tricyclic indoles that potently inhibit Mcl-1 using fragment-based methods and structure-based design. | Burke JP, Bian Z, Shaw S, Zhao B, Goodwin CM, Belmar J, Browning CF, Vigil D, Friberg A, Camper DV, Rossanese OW, Lee T, Olejniczak ET, Fesik SW | Journal of medicinal chemistry | 25844895 | J Med Chem | 2015 May 14 |
Fragment-based screening of the bromodomain of ATAD2. | Harner MJ, Chauder BA, Phan J, Fesik SW | Journal of medicinal chemistry | 25314628 | J Med Chem | 2014 Nov 26 |
Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC. | Thomas LR, Wang Q, Grieb BC, Phan J, Foshage AM, Sun Q, Olejniczak ET, Clark T, Dey S, Lorey S, Alicie B, Howard GC, Cawthon B, Ess KC, Eischen CM, Zhao Z, Fesik SW, Tansey WP | Molecular cell | 25818646 | Mol Cell | 2015 May 7 |
Discovery of a potent inhibitor of replication protein a protein-protein interactions using a fragment-linking approach. | Frank AO, Feldkamp MD, Kennedy JP, Waterson AG, Pelz NF, Patrone JD, Vangamudi B, Camper DV, Rossanese OW, Chazin WJ, Fesik SW | Journal of medicinal chemistry | 24147804 | J Med Chem | 2013 Nov 27 |
Surface reengineering of RPA70N enables cocrystallization with an inhibitor of the replication protein A interaction motif of ATR interacting protein. | Feldkamp MD, Frank AO, Kennedy JP, Patrone JD, Vangamudi B, Waterson AG, Fesik SW, Chazin WJ | Biochemistry | 23962067 | Biochemistry | 2013 Sep 17 |
Discovery of potent myeloid cell leukemia 1 (Mcl-1) inhibitors using fragment-based methods and structure-based design. | Friberg A, Vigil D, Zhao B, Daniels RN, Burke JP, Garcia-Barrantes PM, Camper D, Chauder BA, Lee T, Olejniczak ET, Fesik SW | Journal of medicinal chemistry | 23244564 | J Med Chem | 2013 Jan 10 |
A method for the second-site screening of K-Ras in the presence of a covalently attached first-site ligand. | Sun Q, Phan J, Friberg AR, Camper DV, Olejniczak ET, Fesik SW | Journal of biomolecular NMR | 25087006 | J Biomol NMR | 2014 Sep |
Fragment-based drug discovery using NMR spectroscopy. | Harner MJ, Frank AO, Fesik SW | Journal of biomolecular NMR | 23686385 | J Biomol NMR | 2013 Jun |
MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation. | Lee KM, Giltnane JM, Balko JM, Schwarz LJ, Guerrero-Zotano AL, Hutchinson KE, Nixon MJ, Estrada MV, Sánchez V, Sanders ME, Lee T, Gómez H, Lluch A, Pérez-Fidalgo JA, Wolf MM, Andrejeva G, Rathmell JC, Fesik SW, Arteaga CL | Cell metabolism | 28978427 | Cell Metab | 2017 Oct 3 |
Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods. | Pelz NF, Bian Z, Zhao B, Shaw S, Tarr JC, Belmar J, Gregg C, Camper DV, Goodwin CM, Arnold AL, Sensintaffar JL, Friberg A, Rossanese OW, Lee T, Olejniczak ET, Fesik SW | Journal of medicinal chemistry | 26878343 | J Med Chem | 2016 Mar 10 |
Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS. | Hodges TR, Abbott JR, Little AJ, Sarkar D, Salovich JM, Howes JE, Akan DT, Sai J, Arnold AL, Browning C, Burns MC, Sobolik T, Sun Q, Beesetty Y, Coker JA, Scharn D, Stadtmueller H, Rossanese OW, Phan J, Waterson AG, McConnell DB, Fesik SW | Journal of medicinal chemistry | 30205005 | J Med Chem | 2018 Oct 11 |
Drugging the undruggable RAS: Mission possible? | Cox AD, Fesik SW, Kimmelman AC, Luo J, Der CJ | Nature reviews. Drug discovery | 25323927 | Nat Rev Drug Discov | 2014 Nov |
Discovery and biological characterization of potent myeloid cell leukemia-1 inhibitors. | Lee T, Bian Z, Zhao B, Hogdal LJ, Sensintaffar JL, Goodwin CM, Belmar J, Shaw S, Tarr JC, Veerasamy N, Matulis SM, Koss B, Fischer MA, Arnold AL, Camper DV, Browning CF, Rossanese OW, Budhraja A, Opferman J, Boise LH, Savona MR, Letai A, Olejniczak ET, Fesik SW | FEBS letters | 27878989 | FEBS Lett | 2017 Jan |
Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange. | Burns MC, Sun Q, Daniels RN, Camper D, Kennedy JP, Phan J, Olejniczak ET, Lee T, Waterson AG, Rossanese OW, Fesik SW | Proceedings of the National Academy of Sciences of the United States of America | 24550516 | Proc Natl Acad Sci U S A | 2014 Mar 4 |
Discovery of Protein-Protein Interaction Inhibitors of Replication Protein A. | Patrone JD, Kennedy JP, Frank AO, Feldkamp MD, Vangamudi B, Pelz NF, Rossanese OW, Waterson AG, Chazin WJ, Fesik SW | ACS medicinal chemistry letters | 23914285 | ACS Med Chem Lett | 2013 Jul 11 |
Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A. | Patrone JD, Pelz NF, Bates BS, Souza-Fagundes EM, Vangamudi B, Camper DV, Kuznetsov AG, Browning CF, Feldkamp MD, Frank AO, Gilston BA, Olejniczak ET, Rossanese OW, Waterson AG, Chazin WJ, Fesik SW | ChemMedChem | 26748787 | ChemMedChem | 2016 Apr 19 |
Discovery of Sulfonamide-Derived Agonists of SOS1-Mediated Nucleotide Exchange on RAS Using Fragment-Based Methods. | Sarkar D, Olejniczak ET, Phan J, Coker JA, Sai J, Arnold A, Beesetty Y, Waterson AG, Fesik SW | Journal of medicinal chemistry | 32673492 | J Med Chem | 2020 Aug 13 |
Dynamic states of population activity in prefrontal cortical networks of freely-moving macaque. | Milton R, Shahidi N, Dragoi V | Nature communications | 32327660 | Nat Commun | 2020 Apr 23 |
Surpassing fundamental limits of oscillators using nonlinear resonators. | Villanueva LG, Kenig E, Karabalin RB, Matheny MH, Lifshitz R, Cross MC, Roukes ML | Physical review letters | 23679770 | Phys Rev Lett | 2013 Apr 26 |
Surface adsorbate fluctuations and noise in nanoelectromechanical systems. | Yang YT, Callegari C, Feng XL, Roukes ML | Nano letters | 21388120 | Nano Lett | 2011 Apr 13 |
Passive phase noise cancellation scheme. | Kenig E, Cross MC, Lifshitz R, Karabalin RB, Villanueva LG, Matheny MH, Roukes ML | Physical review letters | 23004985 | Phys Rev Lett | 2012 Jun 29 |
Large-scale integration of nanoelectromechanical systems for gas sensing applications. | Bargatin I, Myers EB, Aldridge JS, Marcoux C, Brianceau P, Duraffourg L, Colinet E, Hentz S, Andreucci P, Roukes ML | Nano letters | 22280452 | Nano Lett | 2012 Mar 14 |
Stress-induced variations in the stiffness of micro- and nanocantilever beams. | Karabalin RB, Villanueva LG, Matheny MH, Sader JE, Roukes ML | Physical review letters | 23003973 | Phys Rev Lett | 2012 Jun 8 |
Optimal operating points of oscillators using nonlinear resonators. | Kenig E, Cross MC, Villanueva LG, Karabalin RB, Matheny MH, Lifshitz R, Roukes ML | Physical review. E, Statistical, nonlinear, and soft matter physics | 23214857 | Phys Rev E Stat Nonlin Soft Matter Phys | 2012 Nov |
Nonlinear mode-coupling in nanomechanical systems. | Matheny MH, Villanueva LG, Karabalin RB, Sader JE, Roukes ML | Nano letters | 23496001 | Nano Lett | 2013 Apr 10 |
Nanoelectromechanical resonator arrays for ultrafast, gas-phase chromatographic chemical analysis. | Li M, Myers EB, Tang HX, Aldridge SJ, McCaig HC, Whiting JJ, Simonson RJ, Lewis NS, Roukes ML | Nano letters | 20795729 | Nano Lett | 2010 Oct 13 |
Comparative advantages of mechanical biosensors. | Arlett JL, Myers EB, Roukes ML | Nature nanotechnology | 21441911 | Nat Nanotechnol | 2011 Apr |
Maternal nutrition induces pervasive gene expression changes but no detectable DNA methylation differences in the liver of adult offspring. | Cannon MV, Buchner DA, Hester J, Miller H, Sehayek E, Nadeau JH, Serre D | PloS one | 24594983 | PLoS One | 2014 |
CMV infection, TLR-2 and -4 expression, and cytokine profiles in early-onset preeclampsia with HELLP syndrome. | Xie F, von Dadelszen P, Nadeau J | American journal of reproductive immunology (New York, N.Y. : 1989) | 24612145 | Am J Reprod Immunol | 2014 Apr |
Report of the National Heart, Lung, and Blood Institute Working Group on epigenetics and hypertension. | Cowley AW Jr, Nadeau JH, Baccarelli A, Berecek K, Fornage M, Gibbons GH, Harrison DG, Liang M, Nathanielsz PW, O'Connor DT, Ordovas J, Peng W, Soares MB, Szyf M, Tolunay HE, Wood KC, Zhao K, Galis ZS | Hypertension (Dallas, Tex. : 1979) | 22431584 | Hypertension | 2012 May |
Transgenerational epigenetic effects of the Apobec1 cytidine deaminase deficiency on testicular germ cell tumor susceptibility and embryonic viability. | Nelson VR, Heaney JD, Tesar PJ, Davidson NO, Nadeau JH | Proceedings of the National Academy of Sciences of the United States of America | 22923694 | Proc Natl Acad Sci U S A | 2012 Oct 9 |
Transgenerational genetic effects of the paternal Y chromosome on daughters' phenotypes. | Nelson VR, Spiezio SH, Nadeau JH | Epigenomics | 22121971 | Epigenomics | 2010 Aug |
Transgenerational genetic effects. | Nelson VR, Nadeau JH | Epigenomics | 22122083 | Epigenomics | 2010 Dec |
Genome-wide identification and functional analysis of Apobec-1-mediated C-to-U RNA editing in mouse small intestine and liver. | Blanc V, Park E, Schaefer S, Miller M, Lin Y, Kennedy S, Billing AM, Ben Hamidane H, Graumann J, Mortazavi A, Nadeau JH, Davidson NO | Genome biology | 24946870 | Genome Biol | 2014 Jun 19 |
Identifying and modifying protein-DNA and protein-protein interactions using a bacterial two-hybrid selection system. | Joung JK | Journal of cellular biochemistry. Supplement | 11842428 | J Cell Biochem Suppl | 2001 |
Counter-selectable marker for bacterial-based interaction trap systems. | Meng X, Smith RM, Giesecke AV, Joung JK, Wolfe SA | BioTechniques | 16526407 | Biotechniques | 2006 Feb |
Engineering designer transcription activator-like effector nucleases (TALENs) by REAL or REAL-Fast assembly. | Reyon D, Khayter C, Regan MR, Joung JK, Sander JD | Current protocols in molecular biology | 23026907 | Curr Protoc Mol Biol | 2012 Oct |
Robust, synergistic regulation of human gene expression using TALE activators. | Maeder ML, Linder SJ, Reyon D, Angstman JF, Fu Y, Sander JD, Joung JK | Nature methods | 23396285 | Nat Methods | 2013 Mar |
The bacterial two-hybrid system as a reporter system for analyzing protein-protein interactions. | Giesecke AV, Joung JK | CSH protocols | 21357036 | CSH Protoc | 2007 Mar 1 |
Engineering Cys2His2 zinc finger domains using a bacterial cell-based two-hybrid selection system. | Thibodeau-Beganny S, Joung JK | Methods in molecular biology (Clifton, N.J.) | 18314590 | Methods Mol Biol | 2007 |
In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases. | Sebastiano V, Maeder ML, Angstman JF, Haddad B, Khayter C, Yeo DT, Goodwin MJ, Hawkins JS, Ramirez CL, Batista LF, Artandi SE, Wernig M, Joung JK | Stem cells (Dayton, Ohio) | 21898685 | Stem Cells | 2011 Nov |
A combined yeast/bacteria two-hybrid system: development and evaluation. | Serebriiskii IG, Fang R, Latypova E, Hopkins R, Vinson C, Joung JK, Golemis EA | Molecular & cellular proteomics : MCP | 15781424 | Mol Cell Proteomics | 2005 Jun |
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ReaChR: a red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation. | Lin JY, Knutsen PM, Muller A, Kleinfeld D, Tsien RY | Nature neuroscience | 23995068 | Nat Neurosci | 2013 Oct |
The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit. | Shih AY, Blinder P, Tsai PS, Friedman B, Stanley G, Lyden PD, Kleinfeld D | Nature neuroscience | 23242312 | Nat Neurosci | 2013 Jan |
Two-photon microscopy as a tool to study blood flow and neurovascular coupling in the rodent brain. | Shih AY, Driscoll JD, Drew PJ, Nishimura N, Schaffer CB, Kleinfeld D | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism | 22293983 | J Cereb Blood Flow Metab | 2012 Jul |
A polished and reinforced thinned-skull window for long-term imaging of the mouse brain. | Shih AY, Mateo C, Drew PJ, Tsai PS, Kleinfeld D | Journal of visualized experiments : JoVE | 22433225 | J Vis Exp | 2012 Mar 7 |
A high-resolution whole-genome map of key chromatin modifications in the adult Drosophila melanogaster. | Yin H, Sweeney S, Raha D, Snyder M, Lin H | PLoS genetics | 22194694 | PLoS Genet | 2011 Dec |
Reassessment of Piwi binding to the genome and Piwi impact on RNA polymerase II distribution. | Lin H, Chen M, Kundaje A, Valouev A, Yin H, Liu N, Neuenkirchen N, Zhong M, Snyder M | Developmental cell | 25805139 | Dev Cell | 2015 Mar 23 |
Uniting germline and stem cells: the function of Piwi proteins and the piRNA pathway in diverse organisms. | Juliano C, Wang J, Lin H | Annual review of genetics | 21942366 | Annu Rev Genet | 2011 |
The microRNA regulation of stem cells. | Huang XA, Lin H | Wiley interdisciplinary reviews. Developmental biology | 23801669 | Wiley Interdiscip Rev Dev Biol | 2012 Jan-Feb |
PAPI, a novel TUDOR-domain protein, complexes with AGO3, ME31B and TRAL in the nuage to silence transposition. | Liu L, Qi H, Wang J, Lin H | Development (Cambridge, England) | 21447556 | Development | 2011 May |
A major epigenetic programming mechanism guided by piRNAs. | Huang XA, Yin H, Sweeney S, Raha D, Snyder M, Lin H | Developmental cell | 23434410 | Dev Cell | 2013 Mar 11 |
Piwi Is a Key Regulator of Both Somatic and Germline Stem Cells in the Drosophila Testis. | Gonzalez J, Qi H, Liu N, Lin H | Cell reports | 26119740 | Cell Rep | 2015 Jul 7 |
The Yb body, a major site for Piwi-associated RNA biogenesis and a gateway for Piwi expression and transport to the nucleus in somatic cells. | Qi H, Watanabe T, Ku HY, Liu N, Zhong M, Lin H | The Journal of biological chemistry | 21106531 | J Biol Chem | 2011 Feb 4 |
The miRNA Regulation of Stem Cells. | Huang XA, Lin H | Wiley interdisciplinary reviews. Membrane transport and signaling | 23024929 | Wiley Interdiscip Rev Membr Transp Signal | 2012 Jan 1 |
Virtual active touch using randomly patterned intracortical microstimulation. | O'Doherty JE, Lebedev MA, Li Z, Nicolelis MA | IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society | 22207642 | IEEE Trans Neural Syst Rehabil Eng | 2012 Jan |
Adaptive decoding for brain-machine interfaces through Bayesian parameter updates. | Li Z, O'Doherty JE, Lebedev MA, Nicolelis MA | Neural computation | 21919788 | Neural Comput | 2011 Dec |
Active tactile exploration using a brain-machine-brain interface. | O'Doherty JE, Lebedev MA, Ifft PJ, Zhuang KZ, Shokur S, Bleuler H, Nicolelis MA | Nature | 21976021 | Nature | 2011 Oct 5 |
High-side digitally current controlled biphasic bipolar microstimulator. | Hanson TL, Ómarsson B, O'Doherty JE, Peikon ID, Lebedev MA, Nicolelis MA | IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society | 22328184 | IEEE Trans Neural Syst Rehabil Eng | 2012 May |
Chronic spinal cord electrical stimulation protects against 6-hydroxydopamine lesions. | Yadav AP, Fuentes R, Zhang H, Vinholo T, Wang CH, Freire MA, Nicolelis MA | Scientific reports | 24452435 | Sci Rep | 2014 Jan 23 |
Creating a neuroprosthesis for active tactile exploration of textures. | O'Doherty JE, Shokur S, Medina LE, Lebedev MA, Nicolelis MAL | Proceedings of the National Academy of Sciences of the United States of America | 31591224 | Proc Natl Acad Sci U S A | 2019 Oct 22 |
A Brain to Spine Interface for Transferring Artificial Sensory Information. | Yadav AP, Li D, Nicolelis MAL | Scientific reports | 31964948 | Sci Rep | 2020 Jan 21 |
Subcortical neuronal ensembles: an analysis of motor task association, tremor, oscillations, and synchrony in human patients. | Hanson TL, Fuller AM, Lebedev MA, Turner DA, Nicolelis MA | The Journal of neuroscience : the official journal of the Society for Neuroscience | 22723703 | J Neurosci | 2012 Jun 20 |
Reprogramming movements: extraction of motor intentions from cortical ensemble activity when movement goals change. | Ifft PJ, Lebedev MA, Nicolelis MA | Frontiers in neuroengineering | 22826698 | Front Neuroeng | 2012 |
Chronic, wireless recordings of large-scale brain activity in freely moving rhesus monkeys. | Schwarz DA, Lebedev MA, Hanson TL, Dimitrov DF, Lehew G, Meloy J, Rajangam S, Subramanian V, Ifft PJ, Li Z, Ramakrishnan A, Tate A, Zhuang KZ, Nicolelis MA | Nature methods | 24776634 | Nat Methods | 2014 Jun |
Stochastic facilitation of artificial tactile sensation in primates. | Medina LE, Lebedev MA, O'Doherty JE, Nicolelis MA | The Journal of neuroscience : the official journal of the Society for Neuroscience | 23055496 | J Neurosci | 2012 Oct 10 |
Cortical correlates of fitts' law. | Ifft PJ, Lebedev MA, Nicolelis MA | Frontiers in integrative neuroscience | 22275888 | Front Integr Neurosci | 2011 |
Analysis of neuronal ensemble activity reveals the pitfalls and shortcomings of rotation dynamics. | Lebedev MA, Ossadtchi A, Mill NA, Urpí NA, Cervera MR, Nicolelis MAL | Scientific reports | 31831758 | Sci Rep | 2019 Dec 12 |
A simple and efficient route to the FKBP-binding domain from rapamycin. | Li W, Bhat S, Liu JO | Tetrahedron letters | 21894238 | Tetrahedron Lett | 2011 Sep 28 |
Rapamycin-inspired macrocycles with new target specificity. | Guo Z, Hong SY, Wang J, Rehan S, Liu W, Peng H, Das M, Li W, Bhat S, Peiffer B, Ullman BR, Tse CM, Tarmakova Z, Schiene-Fischer C, Fischer G, Coe I, Paavilainen VO, Sun Z, Liu JO | Nature chemistry | 30532015 | Nat Chem | 2019 Mar |
Verapamil, and its metabolite norverapamil, inhibit macrophage-induced, bacterial efflux pump-mediated tolerance to multiple anti-tubercular drugs. | Adams KN, Szumowski JD, Ramakrishnan L | The Journal of infectious diseases | 24532601 | J Infect Dis | 2014 Aug 1 |
Combinatorial programming of human neuronal progenitors using magnetically-guided stoichiometric mRNA delivery. | Azimi SM, Sheridan SD, Ghannad-Rezaie M, Eimon PM, Yanik MF | eLife | 29714688 | Elife | 2018 May 1 |
TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species. | Roca FJ, Ramakrishnan L | Cell | 23582643 | Cell | 2013 Apr 25 |
Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids. | Cambier CJ, Takaki KK, Larson RP, Hernandez RE, Tobin DM, Urdahl KB, Cosma CL, Ramakrishnan L | Nature | 24336213 | Nature | 2014 Jan 9 |
Evaluation of the pathogenesis and treatment of Mycobacterium marinum infection in zebrafish. | Takaki K, Davis JM, Winglee K, Ramakrishnan L | Nature protocols | 23680983 | Nat Protoc | 2013 Jun |
Computer-Assisted Transgenesis of Caenorhabditis elegans for Deep Phenotyping. | Gilleland CL, Falls AT, Noraky J, Heiman MG, Yanik MF | Genetics | 26163188 | Genetics | 2015 Sep |
Strategic protein target analysis for developing drugs to stop dental caries. | Horst JA, Pieper U, Sali A, Zhan L, Chopra G, Samudrala R, Featherstone JD | Advances in dental research | 22899687 | Adv Dent Res | 2012 Sep |
LoCo: a novel main chain scoring function for protein structure prediction based on local coordinates. | Moughon SE, Samudrala R | BMC bioinformatics | 21920038 | BMC Bioinformatics | 2011 Sep 15 |
Structure prediction of partial-length protein sequences. | Laurenzi A, Hung LH, Samudrala R | International journal of molecular sciences | 23867606 | Int J Mol Sci | 2013 Jul 17 |
CANDOCK: Chemical Atomic Network-Based Hierarchical Flexible Docking Algorithm Using Generalized Statistical Potentials. | Fine J, Konc J, Samudrala R, Chopra G | Journal of chemical information and modeling | 32069042 | J Chem Inf Model | 2020 Mar 23 |
Shotgun drug repurposing biotechnology to tackle epidemics and pandemics. | Mangione W, Falls Z, Melendy T, Chopra G, Samudrala R | Drug discovery today | 32405249 | Drug Discov Today | 2020 Jul |
Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function. | Palanikumar L, Karpauskaite L, Al-Sayegh M, Chehade I, Alam M, Hassan S, Maity D, Ali L, Kalmouni M, Hunashal Y, Ahmed J, Houhou T, Karapetyan S, Falls Z, Samudrala R, Pasricha R, Esposito G, Afzal AJ, Hamilton AD, Kumar S, Magzoub M | Nature communications | 34172723 | Nat Commun | 2021 Jun 25 |
A Systematic Review of Computational Drug Discovery, Development, and Repurposing for Ebola Virus Disease Treatment. | Schuler J, Hudson ML, Schwartz D, Samudrala R | Molecules (Basel, Switzerland) | 29053626 | Molecules | 2017 Oct 20 |
Computational Grafting of Epitopes. | Manish M, Mishra S, Pahuja M, Anand A, Subbarao N, Samudrala R | Methods in molecular biology (Clifton, N.J.) | 37258909 | Methods Mol Biol | 2023 |
A fluorescence-based, gain-of-signal, live cell system to evaluate SARS-CoV-2 main protease inhibition. | Dey-Rao R, Smith GR, Timilsina U, Falls Z, Samudrala R, Stavrou S, Melendy T | Antiviral research | 34626674 | Antiviral Res | 2021 Nov |
Antiviral Approaches against Influenza Virus. | Kumari R, Sharma SD, Kumar A, Ende Z, Mishina M, Wang Y, Falls Z, Samudrala R, Pohl J, Knight PR, Sambhara S | Clinical microbiology reviews | 36645300 | Clin Microbiol Rev | 2023 Mar 23 |
Exploration of interaction scoring criteria in the CANDO platform. | Falls Z, Mangione W, Schuler J, Samudrala R | BMC research notes | 31174591 | BMC Res Notes | 2019 Jun 7 |
A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex. | Chatrikhi R, Feeney CF, Pulvino MJ, Alachouzos G, MacRae AJ, Falls Z, Rai S, Brennessel WW, Jenkins JL, Walter MJ, Graubert TA, Samudrala R, Jurica MS, Frontier AJ, Kielkopf CL | Cell chemical biology | 33689684 | Cell Chem Biol | 2021 Aug 19 |
Accelerated protein structure comparison using TM-score-GPU. | Hung LH, Samudrala R | Bioinformatics (Oxford, England) | 22718788 | Bioinformatics | 2012 Aug 15 |
Multiscale modelling of relationships between protein classes and drug behavior across all diseases using the CANDO platform. | Sethi G, Chopra G, Samudrala R | Mini reviews in medicinal chemistry | 25694071 | Mini Rev Med Chem | 2015 |
Homo-dimerization and ligand binding by the leucine-rich repeat domain at RHG1/RFS2 underlying resistance to two soybean pathogens. | Afzal AJ, Srour A, Goil A, Vasudaven S, Liu T, Samudrala R, Dogra N, Kohli P, Malakar A, Lightfoot DA | BMC plant biology | 23497186 | BMC Plant Biol | 2013 Mar 15 |
Fingerprinting CANDO: Increased Accuracy with Structure- and Ligand-Based Shotgun Drug Repurposing. | Schuler J, Samudrala R | ACS omega | 31656912 | ACS Omega | 2019 Oct 22 |
Identifying Protein Features Responsible for Improved Drug Repurposing Accuracies Using the CANDO Platform: Implications for Drug Design. | Mangione W, Samudrala R | Molecules (Basel, Switzerland) | 30621144 | Molecules | 2019 Jan 4 |
CANDO and the infinite drug discovery frontier. | Minie M, Chopra G, Sethi G, Horst J, White G, Roy A, Hatti K, Samudrala R | Drug discovery today | 24980786 | Drug Discov Today | 2014 Sep |
Evaluating the performance of drug-repurposing technologies. | Schuler J, Falls Z, Mangione W, Hudson ML, Bruggemann L, Samudrala R | Drug discovery today | 34400352 | Drug Discov Today | 2022 Jan |
Optimal COVID-19 therapeutic candidate discovery using the CANDO platform. | Mangione W, Falls Z, Samudrala R | Frontiers in pharmacology | 36091793 | Front Pharmacol | 2022 |
Identifying Protein Features and Pathways Responsible for Toxicity Using Machine Learning and Tox21: Implications for Predictive Toxicology. | Moukheiber L, Mangione W, Moukheiber M, Maleki S, Falls Z, Gao M, Samudrala R | Molecules (Basel, Switzerland) | 35566372 | Molecules | 2022 May 8 |
Strategies for robust, accurate, and generalizable benchmarking of drug discovery platforms. | Van Norden M, Mangione W, Falls Z, Samudrala R | bioRxiv : the preprint server for biology | 39764006 | bioRxiv | 2024 Dec 16 |
Exploring Polypharmacology in Drug Discovery and Repurposing Using the CANDO Platform. | Chopra G, Samudrala R | Current pharmaceutical design | 27013226 | Curr Pharm Des | 2016 |
Shotgun drug repurposing biotechnology to tackle epidemics and pandemics. | Mangione W, Falls Z, Melendy T, Chopra G, Samudrala R | ChemRxiv : the preprint server for chemistry | 32511286 | ChemRxiv | 2020 May 4 |
Linking Genome and Exposome: Computational Analysis of Human Variation in Chemical-Target Interactions. | Bruggemann L, Hawthorne C, Samudrala R, Lopez-Campos GH | Studies in health technology and informatics | 32570644 | Stud Health Technol Inform | 2020 Jun 16 |
Multiscale Virtual Screening Optimization for Shotgun Drug Repurposing Using the CANDO Platform. | Hudson ML, Samudrala R | Molecules (Basel, Switzerland) | 33925237 | Molecules | 2021 Apr 28 |
Multiscale Analysis and Validation of Effective Drug Combinations Targeting Driver KRAS Mutations in Non-Small Cell Lung Cancer. | Bruggemann L, Falls Z, Mangione W, Schwartz SA, Battaglia S, Aalinkeel R, Mahajan SD, Samudrala R | International journal of molecular sciences | 36674513 | Int J Mol Sci | 2023 Jan 5 |
The impact of nucleosome structure on CRISPR/Cas9 fidelity. | Handelmann CR, Tsompana M, Samudrala R, Buck MJ | Nucleic acids research | 36727449 | Nucleic Acids Res | 2023 Mar 21 |
The Promise and Challenge of Digital Biology. | Minie ME, Samudrala R | Journal of bioengineering & biomedical science | 30338132 | J Bioeng Biomed Sci | 2013 |
Computational chemoproteomics to understand the role of selected psychoactives in treating mental health indications. | Fine J, Lackner R, Samudrala R, Chopra G | Scientific reports | 31511563 | Sci Rep | 2019 Sep 11 |
Rv0100, a proposed acyl carrier protein in Mycobacterium tuberculosis: expression, purification and crystallization. Corrigendum. | Bondoc JMG, Gutka HJ, Almutairi MM, Patwell R, Rutter MW, Wolf NM, Samudrala R, Mehboob S, Dementiev A, Abad-Zapatero C, Movahedzadeh F | Acta crystallographica. Section F, Structural biology communications | 32254053 | Acta Crystallogr F Struct Biol Commun | 2020 Apr 1 |
Proteomic Network Analysis of Bronchoalveolar Lavage Fluid in Ex-Smokers to Discover Implicated Protein Targets and Novel Drug Treatments for Chronic Obstructive Pulmonary Disease. | Mammen MJ, Tu C, Morris MC, Richman S, Mangione W, Falls Z, Qu J, Broderick G, Sethi S, Samudrala R | Pharmaceuticals (Basel, Switzerland) | 35631392 | Pharmaceuticals (Basel) | 2022 May 1 |
A Deep-Learning Proteomic-Scale Approach for Drug Design. | Overhoff B, Falls Z, Mangione W, Samudrala R | Pharmaceuticals (Basel, Switzerland) | 34959678 | Pharmaceuticals (Basel) | 2021 Dec 7 |
The enzymatic and metabolic capabilities of early life. | Goldman AD, Baross JA, Samudrala R | PloS one | 22970111 | PLoS One | 2012 |
Rv0100, a proposed acyl carrier protein in Mycobacterium tuberculosis: expression, purification and crystallization. | Bondoc JMG, Gutka HJ, Almutairi MM, Patwell R, Rutter MW, Wolf NM, Samudrala R, Mehboob S, Movahedzadeh F | Acta crystallographica. Section F, Structural biology communications | 31584013 | Acta Crystallogr F Struct Biol Commun | 2019 Oct 1 |
Combating Ebola with Repurposed Therapeutics Using the CANDO Platform. | Chopra G, Kaushik S, Elkin PL, Samudrala R | Molecules (Basel, Switzerland) | 27898018 | Molecules | 2016 Nov 25 |
Self-assembly of filamentous amelogenin requires calcium and phosphate: from dimers via nanoribbons to fibrils. | Martinez-Avila O, Wu S, Kim SJ, Cheng Y, Khan F, Samudrala R, Sali A, Horst JA, Habelitz S | Biomacromolecules | 22974364 | Biomacromolecules | 2012 Nov 12 |
cando.py: Open Source Software for Predictive Bioanalytics of Large Scale Drug-Protein-Disease Data. | Mangione W, Falls Z, Chopra G, Samudrala R | Journal of chemical information and modeling | 32515949 | J Chem Inf Model | 2020 Sep 28 |
Association of C>U RNA Editing with Human Disease Variants. | Mandloi S, Falls Z, Deng R, Samudrala R, Elkin PL | Studies in health technology and informatics | 32570581 | Stud Health Technol Inform | 2020 Jun 16 |
Accurate Prediction of Inhibitor Binding to HIV-1 Protease Using CANDOCK. | Falls Z, Fine J, Chopra G, Samudrala R | Frontiers in chemistry | 35111726 | Front Chem | 2021 |
Effects of natural selection and gene conversion on the evolution of human glycophorins coding for MNS blood polymorphisms in malaria-endemic African populations. | Ko WY, Kaercher KA, Giombini E, Marcatili P, Froment A, Ibrahim M, Lema G, Nyambo TB, Omar SA, Wambebe C, Ranciaro A, Hirbo JB, Tishkoff SA | American journal of human genetics | 21664997 | Am J Hum Genet | 2011 Jun 10 |
Genetic structure in African populations: implications for human demographic history. | Lambert CA, Tishkoff SA | Cold Spring Harbor symposia on quantitative biology | 20453204 | Cold Spring Harb Symp Quant Biol | 2009 |
Living the high life: high-altitude adaptation. | Scheinfeldt LB, Tishkoff SA | Genome biology | 20979669 | Genome Biol | 2010 |
The evolution of human genetic and phenotypic variation in Africa. | Campbell MC, Tishkoff SA | Current biology : CB | 20178763 | Curr Biol | 2010 Feb 23 |
A founder mutation in LEPRE1 carried by 1.5% of West Africans and 0.4% of African Americans causes lethal recessive osteogenesis imperfecta. | Cabral WA, Barnes AM, Adeyemo A, Cushing K, Chitayat D, Porter FD, Panny SR, Gulamali-Majid F, Tishkoff SA, Rebbeck TR, Gueye SM, Bailey-Wilson JE, Brody LC, Rotimi CN, Marini JC | Genetics in medicine : official journal of the American College of Medical Genetics | 22281939 | Genet Med | 2012 May |
Evidence from Cameroon reveals differences in the genetic structure and histories of chimpanzee populations. | Gonder MK, Locatelli S, Ghobrial L, Mitchell MW, Kujawski JT, Lankester FJ, Stewart CB, Tishkoff SA | Proceedings of the National Academy of Sciences of the United States of America | 21368170 | Proc Natl Acad Sci U S A | 2011 Mar 22 |
Haplotype variation and genotype imputation in African populations. | Huang L, Jakobsson M, Pemberton TJ, Ibrahim M, Nyambo T, Omar S, Pritchard JK, Tishkoff SA, Rosenberg NA | Genetic epidemiology | 22125220 | Genet Epidemiol | 2011 Dec |
Evolution of functionally diverse alleles associated with PTC bitter taste sensitivity in Africa. | Campbell MC, Ranciaro A, Froment A, Hirbo J, Omar S, Bodo JM, Nyambo T, Lema G, Zinshteyn D, Drayna D, Breslin PA, Tishkoff SA | Molecular biology and evolution | 22130969 | Mol Biol Evol | 2012 Apr |
Recent human adaptation: genomic approaches, interpretation and insights. | Scheinfeldt LB, Tishkoff SA | Nature reviews. Genetics | 24052086 | Nat Rev Genet | 2013 Oct |
Obesity-susceptibility loci and the tails of the pediatric BMI distribution. | Mitchell JA, Hakonarson H, Rebbeck TR, Grant SF | Obesity (Silver Spring, Md.) | 23408508 | Obesity (Silver Spring) | 2013 Jun |
Patterns of nucleotide and haplotype diversity at ICAM-1 across global human populations with varying levels of malaria exposure. | Gomez F, Tomas G, Ko WY, Ranciaro A, Froment A, Ibrahim M, Lema G, Nyambo TB, Omar SA, Wambebe C, Hirbo JB, Rocha J, Tishkoff SA | Human genetics | 23609612 | Hum Genet | 2013 Sep |
Colloquium paper: working toward a synthesis of archaeological, linguistic, and genetic data for inferring African population history. | Scheinfeldt LB, Soi S, Tishkoff SA | Proceedings of the National Academy of Sciences of the United States of America | 20445100 | Proc Natl Acad Sci U S A | 2010 May 11 |
Characterization of genetic variation and natural selection at the arylamine N-acetyltransferase genes in global human populations. | Mortensen HM, Froment A, Lema G, Bodo JM, Ibrahim M, Nyambo TB, Omar SA, Tishkoff SA | Pharmacogenomics | 21995608 | Pharmacogenomics | 2011 Nov |
Patterns of ancestry, signatures of natural selection, and genetic association with stature in Western African pygmies. | Jarvis JP, Scheinfeldt LB, Soi S, Lambert C, Omberg L, Ferwerda B, Froment A, Bodo JM, Beggs W, Hoffman G, Mezey J, Tishkoff SA | PLoS genetics | 22570615 | PLoS Genet | 2012 |
Small heat shock proteins in redox metabolism: implications for cardiovascular diseases. | Christians ES, Ishiwata T, Benjamin IJ | The international journal of biochemistry & cell biology | 22710345 | Int J Biochem Cell Biol | 2012 Oct |
Sustained activation of nuclear erythroid 2-related factor 2/antioxidant response element signaling promotes reductive stress in the human mutant protein aggregation cardiomyopathy in mice. | Rajasekaran NS, Varadharaj S, Khanderao GD, Davidson CJ, Kannan S, Firpo MA, Zweier JL, Benjamin IJ | Antioxidants & redox signaling | 21126175 | Antioxid Redox Signal | 2011 Mar 15 |
Proteostasis and REDOX state in the heart. | Christians ES, Benjamin IJ | American journal of physiology. Heart and circulatory physiology | 22003057 | Am J Physiol Heart Circ Physiol | 2012 Jan 1 |
Effects of redox state on the efficient uptake of cell permeable Peptide in Mammalian cells. | Squires S, Christians E, Riedel M, Timothy D, Rodesch CK, Marvin J, Benjamin I | The open biochemistry journal | 23919090 | Open Biochem J | 2013 |
Aggregate-prone R120GCRYAB triggers multifaceted modifications of the thioredoxin system. | Banerjee Mustafi S, Grose JH, Zhang H, Pratt GW, Sadoshima J, Christians ES, Benjamin IJ | Antioxidants & redox signaling | 24180415 | Antioxid Redox Signal | 2014 Jun 20 |
Reductive stress linked to small HSPs, G6PD, and Nrf2 pathways in heart disease. | Brewer AC, Mustafi SB, Murray TV, Rajasekaran NS, Benjamin IJ | Antioxidants & redox signaling | 22938199 | Antioxid Redox Signal | 2013 Mar 20 |
Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice. | Rajasekaran NS, Connell P, Christians ES, Yan LJ, Taylor RP, Orosz A, Zhang XQ, Stevenson TJ, Peshock RM, Leopold JA, Barry WH, Loscalzo J, Odelberg SJ, Benjamin IJ | Cell | 17693254 | Cell | 2007 Aug 10 |
HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth. | Su KH, Cao J, Tang Z, Dai S, He Y, Sampson SB, Benjamin IJ, Dai C | Nature cell biology | 27043084 | Nat Cell Biol | 2016 May |
Patient-derived xenografts of low-grade B-cell lymphomas demonstrate roles of the tumor microenvironment. | Burack WR, Spence JM, Spence JP, Spence SA, Rock PJ, Shenoy GN, Shultz LD, Bankert RB, Bernstein SH | Blood advances | 29296768 | Blood Adv | 2017 Jul 11 |
Chaperones and cardiac misfolding protein diseases. | Christians ES, Mustafi SB, Benjamin IJ | Current protein & peptide science | 24694370 | Curr Protein Pept Sci | 2014 May |
Glutathione-dependent reductive stress triggers mitochondrial oxidation and cytotoxicity. | Zhang H, Limphong P, Pieper J, Liu Q, Rodesch CK, Christians E, Benjamin IJ | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 22202674 | FASEB J | 2012 Apr |
Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome. | Grose JH, Langston K, Wang X, Squires S, Mustafi SB, Hayes W, Neubert J, Fischer SK, Fasano M, Saunders GM, Dai Q, Christians E, Lewandowski ED, Ping P, Benjamin IJ | PloS one | 26465331 | PLoS One | 2015 |
Profibrotic COVID-19 subphenotype exhibits enhanced localized ER-dependent HSP47(+) expression in cardiac myofibroblasts in situ. | Jacobs ER, Ross GR, Padilla N, Pan AY, Liegl M, Puzyrenko A, Lai S, Dai Q, Uche N, Rubenstein JC, North PE, Ibrahim EH, Sun Y, Felix JC, Rui H, Benjamin IJ | Journal of molecular and cellular cardiology | 37839656 | J Mol Cell Cardiol | 2023 Dec |
Selective degradation of aggregate-prone CryAB mutants by HSPB1 is mediated by ubiquitin-proteasome pathways. | Zhang H, Rajasekaran NS, Orosz A, Xiao X, Rechsteiner M, Benjamin IJ | Journal of molecular and cellular cardiology | 20863832 | J Mol Cell Cardiol | 2010 Dec |
HSPB2 is dispensable for the cardiac hypertrophic response but reduces mitochondrial energetics following pressure overload in mice. | Ishiwata T, Orosz A, Wang X, Mustafi SB, Pratt GW, Christians ES, Boudina S, Abel ED, Benjamin IJ | PloS one | 22870288 | PLoS One | 2012 |
The NADPH metabolic network regulates human αB-crystallin cardiomyopathy and reductive stress in Drosophila melanogaster. | Xie HB, Cammarato A, Rajasekaran NS, Zhang H, Suggs JA, Lin HC, Bernstein SI, Benjamin IJ, Golic KG | PLoS genetics | 23818860 | PLoS Genet | 2013 Jun |
Rescue of αB Crystallin (HSPB5) Mutants Associated Protein Aggregation by Co-Expression of HSPB5 Partners. | Hussein RM, Benjamin IJ, Kampinga HH | PloS one | 25961584 | PLoS One | 2015 |
Targeting endoglin, an auxiliary transforming growth factor β coreceptor, to prevent fibrosis and heart failure. | Benjamin IJ | Circulation | 22592899 | Circulation | 2012 Jun 5 |
Vasoactive intestinal polypeptide mediates circadian rhythms in mammalian olfactory bulb and olfaction. | Miller JE, Granados-Fuentes D, Wang T, Marpegan L, Holy TE, Herzog ED | The Journal of neuroscience : the official journal of the Society for Neuroscience | 24760863 | J Neurosci | 2014 Apr 23 |
A Mutation Associated with Stuttering Alters Mouse Pup Ultrasonic Vocalizations. | Barnes TD, Wozniak DF, Gutierrez J, Han TU, Drayna D, Holy TE | Current biology : CB | 27151663 | Curr Biol | 2016 Apr 13 |
Organization of vomeronasal sensory coding revealed by fast volumetric calcium imaging. | Turaga D, Holy TE | The Journal of neuroscience : the official journal of the Society for Neuroscience | 22302803 | J Neurosci | 2012 Feb 1 |
Knockout of Lysosomal Enzyme-Targeting Gene Causes Abnormalities in Mouse Pup Isolation Calls. | Barnes TD, Holy TE | Frontiers in behavioral neuroscience | 28101008 | Front Behav Neurosci | 2016 |
Experience-Dependent Plasticity Drives Individual Differences in Pheromone-Sensing Neurons. | Xu PS, Lee D, Holy TE | Neuron | 27537487 | Neuron | 2016 Aug 17 |
An unsolved mystery: the target-recognizing RNA species of microRNA genes. | Chen CZ | Biochimie | 23685275 | Biochimie | 2013 Sep |
Modulating the strength and threshold of NOTCH oncogenic signals by mir-181a-1/b-1. | Fragoso R, Mao T, Wang S, Schaffert S, Gong X, Yue S, Luong R, Min H, Yashiro-Ohtani Y, Davis M, Pear W, Chen CZ | PLoS genetics | 22916024 | PLoS Genet | 2012 |
Loop nucleotides control primary and mature miRNA function in target recognition and repression. | Yue SB, Trujillo RD, Tang Y, O'Gorman WE, Chen CZ | RNA biology | 22142974 | RNA Biol | 2011 Nov-Dec |
The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression. | Wong P, Iwasaki M, Somervaille TC, Ficara F, Carico C, Arnold C, Chen CZ, Cleary ML | Cancer research | 20406979 | Cancer Res | 2010 May 1 |
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Early Seizures Prematurely Unsilence Auditory Synapses to Disrupt Thalamocortical Critical Period Plasticity. | Sun H, Takesian AE, Wang TT, Lippman-Bell JJ, Hensch TK, Jensen FE | Cell reports | 29847785 | Cell Rep | 2018 May 29 |
Prolonged Period of Cortical Plasticity upon Redox Dysregulation in Fast-Spiking Interneurons. | Morishita H, Cabungcal JH, Chen Y, Do KQ, Hensch TK | Biological psychiatry | 25758057 | Biol Psychiatry | 2015 Sep 15 |
Lynx1, a cholinergic brake, limits plasticity in adult visual cortex. | Morishita H, Miwa JM, Heintz N, Hensch TK | Science (New York, N.Y.) | 21071629 | Science | 2010 Nov 26 |
Analytical approaches to RNA profiling data for the identification of genes enriched in specific cells. | Dougherty JD, Schmidt EF, Nakajima M, Heintz N | Nucleic acids research | 20308160 | Nucleic Acids Res | 2010 Jul |
NMDA receptor regulation prevents regression of visual cortical function in the absence of Mecp2. | Durand S, Patrizi A, Quast KB, Hachigian L, Pavlyuk R, Saxena A, Carninci P, Hensch TK, Fagiolini M | Neuron | 23259945 | Neuron | 2012 Dec 20 |
Quantifying Pituitary-Adrenal Dynamics and Deconvolution of Concurrent Cortisol and Adrenocorticotropic Hormone Data by Compressed Sensing. | Faghih RT, Dahleh MA, Adler GK, Klerman EB, Brown EN | IEEE transactions on bio-medical engineering | 25935025 | IEEE Trans Biomed Eng | 2015 Oct |
Beamforming approach to phase-amplitude modulation analysis of multi-channel EEG. | Sampson AL, Babadi B, Prerau MJ, Mukamel EA, Brown EN, Purdon PL | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 23367474 | Annu Int Conf IEEE Eng Med Biol Soc | 2012 |
Assessing the effects of pharmacological agents on respiratory dynamics using time-series modeling. | Wong KF, Gong JJ, Cotten JF, Solt K, Brown EN | IEEE transactions on bio-medical engineering | 23193230 | IEEE Trans Biomed Eng | 2013 Apr |
Inferring evoked brain connectivity through adaptive perturbation. | Lepage KQ, Ching S, Kramer MA | Journal of computational neuroscience | 22990598 | J Comput Neurosci | 2013 Apr |
Psychophysiological signals associated with affective states. | Mauri M, Magagnin V, Cipresso P, Mainardi L, Brown EN, Cerutti S, Villamira M, Barbieri R | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 21096828 | Annu Int Conf IEEE Eng Med Biol Soc | 2010 |
A Granger causality measure for point process models of ensemble neural spiking activity. | Kim S, Putrino D, Ghosh S, Brown EN | PLoS computational biology | 21455283 | PLoS Comput Biol | 2011 Mar |
Tracking brain states under general anesthesia by using global coherence analysis. | Cimenser A, Purdon PL, Pierce ET, Walsh JL, Salazar-Gomez AF, Harrell PG, Tavares-Stoeckel C, Habeeb K, Brown EN | Proceedings of the National Academy of Sciences of the United States of America | 21555565 | Proc Natl Acad Sci U S A | 2011 May 24 |
Instantaneous frequency and amplitude modulation of EEG in the hippocampus reveals state dependent temporal structure. | Nguyen DP, Barbieri R, Wilson MA, Brown EN | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 19163009 | Annu Int Conf IEEE Eng Med Biol Soc | 2008 |
Assessment of hippocampal and autonomic neural activity by point process models. | Barbieri R, Chen Z, Brown EN | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 19163509 | Annu Int Conf IEEE Eng Med Biol Soc | 2008 |
A statistical model for multiphoton calcium imaging of the brain. | Malik WQ, Schummers J, Sur M, Brown EN | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 19964727 | Annu Int Conf IEEE Eng Med Biol Soc | 2009 |
Modeling two-photon calcium fluorescence of episodic V1 recordings using multifrequency analysis. | Zheng HW, Malik WQ, Runyan CA, Sur M, Brown EN | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 22254975 | Annu Int Conf IEEE Eng Med Biol Soc | 2011 |
Functional biases in visual cortex neurons with identified projections to higher cortical targets. | Jarosiewicz B, Schummers J, Malik WQ, Brown EN, Sur M | Current biology : CB | 22305753 | Curr Biol | 2012 Feb 21 |
A spatiotemporal dynamic distributed solution to the MEG inverse problem. | Lamus C, Hämäläinen MS, Temereanca S, Brown EN, Purdon PL | NeuroImage | 22155043 | Neuroimage | 2012 Nov 1 |
Heart Rate Variability and Respiratory Sinus Arrhythmia Assessment of Affective States by Bivariate Autoregressive Spectral Analysis. | Magagnin V, Mauri M, Cipresso P, Mainardi L, Brown E, Cerutti S, Villamira M, Barbieri R | Computing in cardiology | 22158520 | Comput Cardiol (2010) | 2010 |
Phase-based measures of cross-frequency coupling in brain electrical dynamics under general anesthesia. | Mukamel EA, Wong KF, Prerau MJ, Brown EN, Purdon PL | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 22254722 | Annu Int Conf IEEE Eng Med Biol Soc | 2011 |
Real-time closed-loop control in a rodent model of medically induced coma using burst suppression. | Ching S, Liberman MY, Chemali JJ, Westover MB, Kenny JD, Solt K, Purdon PL, Brown EN | Anesthesiology | 23770601 | Anesthesiology | 2013 Oct |
Reference-free harmonic regression technique to remove EEG-fMRI ballistocardiogram artifacts. | Krishnaswamy P, Bonmassar G, Purdon PL, Brown EN | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 24110963 | Annu Int Conf IEEE Eng Med Biol Soc | 2013 |
A real-time brain-machine interface combining motor target and trajectory intent using an optimal feedback control design. | Shanechi MM, Williams ZM, Wornell GW, Hu RC, Powers M, Brown EN | PloS one | 23593130 | PLoS One | 2013 |
Delayed orexin signaling consolidates wakefulness and sleep: physiology and modeling. | Diniz Behn CG, Kopell N, Brown EN, Mochizuki T, Scammell TE | Journal of neurophysiology | 18417630 | J Neurophysiol | 2008 Jun |
Electrical stimulation of the ventral tegmental area induces reanimation from general anesthesia. | Solt K, Van Dort CJ, Chemali JJ, Taylor NE, Kenny JD, Brown EN | Anesthesiology | 24398816 | Anesthesiology | 2014 Aug |
Optogenetics and Chemogenetics. | Vlasov K, Van Dort CJ, Solt K | Methods in enzymology | 29673525 | Methods Enzymol | 2018 |
A Neurologic Examination for Anesthesiologists: Assessing Arousal Level during Induction, Maintenance, and Emergence. | Reshef ER, Schiff ND, Brown EN | Anesthesiology | 30664547 | Anesthesiology | 2019 Mar |
Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology and Improves Cognition. | Martorell AJ, Paulson AL, Suk HJ, Abdurrob F, Drummond GT, Guan W, Young JZ, Kim DN, Kritskiy O, Barker SJ, Mangena V, Prince SM, Brown EN, Chung K, Boyden ES, Singer AC, Tsai LH | Cell | 30879788 | Cell | 2019 Apr 4 |
A Prospective Study of Age-dependent Changes in Propofol-induced Electroencephalogram Oscillations in Children. | Lee JM, Akeju O, Terzakis K, Pavone KJ, Deng H, Houle TT, Firth PG, Shank ES, Brown EN, Purdon PL | Anesthesiology | 28657957 | Anesthesiology | 2017 Aug |
Robust control of burst suppression for medical coma. | Westover MB, Kim SE, Ching S, Purdon PL, Brown EN | Journal of neural engineering | 26020243 | J Neural Eng | 2015 Aug |
Probabilistic Common Spatial Patterns for Multichannel EEG Analysis. | Wu W, Chen Z, Gao X, Li Y, Brown EN, Gao S | IEEE transactions on pattern analysis and machine intelligence | 26005228 | IEEE Trans Pattern Anal Mach Intell | 2015 Mar |
Clinical Electroencephalography for Anesthesiologists: Part I: Background and Basic Signatures. | Purdon PL, Sampson A, Pavone KJ, Brown EN | Anesthesiology | 26275092 | Anesthesiology | 2015 Oct |
Efficient decoding with steady-state Kalman filter in neural interface systems. | Malik WQ, Truccolo W, Brown EN, Hochberg LR | IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society | 21078582 | IEEE Trans Neural Syst Rehabil Eng | 2011 Feb |
Point process time-frequency analysis of respiratory sinus arrhythmia under altered respiration dynamics. | Kodituwakku S, Lazar SW, Indic P, Brown EN, Barbieri R | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 21096135 | Annu Int Conf IEEE Eng Med Biol Soc | 2010 |
Dynamic Cardiovagal Response to Motion Sickness: A Point-Process Heart Rate Variability Study. | Lacount L, Napadow V, Kuo B, Park K, Kim J, Brown E, Barbieri R | Computers in cardiology | 20445767 | Comput Cardiol | 2009 Jan 1 |
Assessment of Baroreflex Control of Heart Rate During General Anesthesia Using a Point Process Method. | Chen Z, Purdon P, Pierce E, Harrell G, Brown E, Barbieri R | Proceedings of the ... IEEE International Conference on Acoustics, Speech, and Signal Processing. ICASSP (Conference) | 20473342 | Proc IEEE Int Conf Acoust Speech Signal Process | 2009 May 26 |
Denoising two-photon calcium imaging data. | Malik WQ, Schummers J, Sur M, Brown EN | PloS one | 21687727 | PLoS One | 2011 |
Discrete time rescaling theorem: determining goodness of fit for discrete time statistical models of neural spiking. | Haslinger R, Pipa G, Brown E | Neural computation | 20608868 | Neural Comput | 2010 Oct |
Activity in the barrel cortex during active behavior and sleep. | Vijayan S, Hale GJ, Moore CI, Brown EN, Wilson M | Journal of neurophysiology | 20164403 | J Neurophysiol | 2010 Apr |
Characterizing nonlinear heartbeat dynamics within a point process framework. | Chen Z, Brown EN, Barbieri R | IEEE transactions on bio-medical engineering | 20172783 | IEEE Trans Biomed Eng | 2010 Jun |
Context matters: the illusive simplicity of macaque V1 receptive fields. | Haslinger R, Pipa G, Lima B, Singer W, Brown EN, Neuenschwander S | PloS one | 22802940 | PLoS One | 2012 |
A unified point process probabilistic framework to assess heartbeat dynamics and autonomic cardiovascular control. | Chen Z, Purdon PL, Brown EN, Barbieri R | Frontiers in physiology | 22375120 | Front Physiol | 2012 |
State-space analysis of time-varying higher-order spike correlation for multiple neural spike train data. | Shimazaki H, Amari S, Brown EN, Grün S | PLoS computational biology | 22412358 | PLoS Comput Biol | 2012 |
Active emergence from propofol general anesthesia is induced by methylphenidate. | Chemali JJ, Van Dort CJ, Brown EN, Solt K | Anesthesiology | 22446983 | Anesthesiology | 2012 May |
Distributed control in a mean-field cortical network model: implications for seizure suppression. | Ching S, Brown EN, Kramer MA | Physical review. E, Statistical, nonlinear, and soft matter physics | 23005798 | Phys Rev E Stat Nonlin Soft Matter Phys | 2012 Aug |
A neurophysiological-metabolic model for burst suppression. | Ching S, Purdon PL, Vijayan S, Kopell NJ, Brown EN | Proceedings of the National Academy of Sciences of the United States of America | 22323592 | Proc Natl Acad Sci U S A | 2012 Feb 21 |
Quantification of the benefit from integrating MEG and EEG data in minimum l2-norm estimation. | Molins A, Stufflebeam SM, Brown EN, Hämäläinen MS | NeuroImage | 18602485 | Neuroimage | 2008 Sep 1 |
Assessment of autonomic control and respiratory sinus arrhythmia using point process models of human heart beat dynamics. | Chen Z, Brown EN, Barbieri R | IEEE transactions on bio-medical engineering | 19272971 | IEEE Trans Biomed Eng | 2009 Jul |
A Bayesian statistical analysis of behavioral facilitation associated with deep brain stimulation. | Smith AC, Shah SA, Hudson AE, Purpura KP, Victor JD, Brown EN, Schiff ND | Journal of neuroscience methods | 19576932 | J Neurosci Methods | 2009 Oct 15 |
A regularized point process generalized linear model for assessing the functional connectivity in the cat motor cortex. | Chen Z, Putrino DF, Ba DE, Ghosh S, Barbieri R, Brown EN | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 19965032 | Annu Int Conf IEEE Eng Med Biol Soc | 2009 |
Brain correlates of autonomic modulation: combining heart rate variability with fMRI. | Napadow V, Dhond R, Conti G, Makris N, Brown EN, Barbieri R | NeuroImage | 18524629 | Neuroimage | 2008 Aug 1 |
Analysis of between-trial and within-trial neural spiking dynamics. | Czanner G, Eden UT, Wirth S, Yanike M, Suzuki WA, Brown EN | Journal of neurophysiology | 18216233 | J Neurophysiol | 2008 May |
Assessing neuronal interactions of cell assemblies during general anesthesia. | Chen Z, Vijayan S, Ching S, Hale G, Flores FJ, Wilson MA, Brown EN | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 22255259 | Annu Int Conf IEEE Eng Med Biol Soc | 2011 |
Instantaneous assessment of autonomic cardiovascular control during general anesthesia. | Chen Z, Citi L, Purdon PL, Brown EN, Barbieri R | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 22256307 | Annu Int Conf IEEE Eng Med Biol Soc | 2011 |
A point process model for auditory neurons considering both their intrinsic dynamics and the spectrotemporal properties of an extrinsic signal. | Plourde E, Delgutte B, Brown EN | IEEE transactions on bio-medical engineering | 21317068 | IEEE Trans Biomed Eng | 2011 Jun |
Assessment of cardio-respiratory interactions in preterm infants by bivariate autoregressive modeling and surrogate data analysis. | Indic P, Bloch-Salisbury E, Bednarek F, Brown EN, Paydarfar D, Barbieri R | Early human development | 21511413 | Early Hum Dev | 2011 Jul |
Statistical inference for assessing functional connectivity of neuronal ensembles with sparse spiking data. | Chen Z, Putrino DF, Ghosh S, Barbieri R, Brown EN | IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society | 20937583 | IEEE Trans Neural Syst Rehabil Eng | 2011 Apr |
Convergence and Stability of a Class of Iteratively Re-weighted Least Squares Algorithms for Sparse Signal Recovery in the Presence of Noise. | Babadi B, Ba D, Purdon PL, Brown EN | IEEE transactions on signal processing : a publication of the IEEE Signal Processing Society | 26549965 | IEEE Trans Signal Process | 2013 Oct 30 |
GABAA circuit mechanisms are associated with ether anesthesia-induced unconsciousness. | Akeju O, Hamilos AE, Song AH, Pavone KJ, Purdon PL, Brown EN | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology | 27178867 | Clin Neurophysiol | 2016 Jun |
Corticoamygdala Transfer of Socially Derived Information Gates Observational Learning. | Allsop SA, Wichmann R, Mills F, Burgos-Robles A, Chang CJ, Felix-Ortiz AC, Vienne A, Beyeler A, Izadmehr EM, Glober G, Cum MI, Stergiadou J, Anandalingam KK, Farris K, Namburi P, Leppla CA, Weddington JC, Nieh EH, Smith AC, Ba D, Brown EN, Tye KM | Cell | 29731170 | Cell | 2018 May 31 |
Disruption of thalamic functional connectivity is a neural correlate of dexmedetomidine-induced unconsciousness. | Akeju O, Loggia ML, Catana C, Pavone KJ, Vazquez R, Rhee J, Contreras Ramirez V, Chonde DB, Izquierdo-Garcia D, Arabasz G, Hsu S, Habeeb K, Hooker JM, Napadow V, Brown EN, Purdon PL | eLife | 25432022 | Elife | 2014 Nov 28 |
The human burst suppression electroencephalogram of deep hypothermia. | Westover MB, Ching S, Kumaraswamy VM, Akeju SO, Pierce E, Cash SS, Kilbride R, Brown EN, Purdon PL | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology | 25649968 | Clin Neurophysiol | 2015 Oct |
Biophysical Modeling of Alpha Rhythms During Halothane-Induced Unconsciousness. | Vijayan S, Ching S, Purdon PL, Brown EN, Kopell NJ | International IEEE/EMBS Conference on Neural Engineering : [proceedings]. International IEEE EMBS Conference on Neural Engineering | 25284633 | Int IEEE EMBS Conf Neural Eng | 2013 |
Effects of sevoflurane and propofol on frontal electroencephalogram power and coherence. | Akeju O, Westover MB, Pavone KJ, Sampson AL, Hartnack KE, Brown EN, Purdon PL | Anesthesiology | 25233374 | Anesthesiology | 2014 Nov |
A comparison of propofol- and dexmedetomidine-induced electroencephalogram dynamics using spectral and coherence analysis. | Akeju O, Pavone KJ, Westover MB, Vazquez R, Prerau MJ, Harrell PG, Hartnack KE, Rhee J, Sampson AL, Habeeb K, Gao L, Pierce ET, Walsh JL, Brown EN, Purdon PL | Anesthesiology | 25187999 | Anesthesiology | 2014 Nov |
Adaptation to elastic loads and BMI robot controls during rat locomotion examined with point-process GLMs. | Song W, Cajigas I, Brown EN, Giszter SF | Frontiers in systems neuroscience | 25972789 | Front Syst Neurosci | 2015 |
In reply. | Purdon PL, Zhou DW, Akeju O, Brown EN | Anesthesiology | 26284863 | Anesthesiology | 2015 Sep |
Age-dependency of sevoflurane-induced electroencephalogram dynamics in children. | Akeju O, Pavone KJ, Thum JA, Firth PG, Westover MB, Puglia M, Shank ES, Brown EN, Purdon PL | British journal of anaesthesia | 26174303 | Br J Anaesth | 2015 Jul |
Statistical modeling of behavioral dynamics during propofol-induced loss of consciousness. | Wong KF, Smith AC, Pierce ET, Harrell PG, Walsh JL, Salazar-Gómez AF, Tavares CL, Purdon PL, Brown EN | Journal of neuroscience methods | 24530701 | J Neurosci Methods | 2014 Apr 30 |
Local cortical dynamics of burst suppression in the anaesthetized brain. | Lewis LD, Ching S, Weiner VS, Peterfreund RA, Eskandar EN, Cash SS, Brown EN, Purdon PL | Brain : a journal of neurology | 23887187 | Brain | 2013 Sep |
Physostigmine and Methylphenidate Induce Distinct Arousal States During Isoflurane General Anesthesia in Rats. | Kenny JD, Chemali JJ, Cotten JF, Van Dort CJ, Kim SE, Ba D, Taylor NE, Brown EN, Solt K | Anesthesia and analgesia | 26991753 | Anesth Analg | 2016 Nov |
Single-neuron dynamics in human focal epilepsy. | Truccolo W, Donoghue JA, Hochberg LR, Eskandar EN, Madsen JR, Anderson WS, Brown EN, Halgren E, Cash SS | Nature neuroscience | 21441925 | Nat Neurosci | 2011 May |
Thalamocortical model for a propofol-induced alpha-rhythm associated with loss of consciousness. | Ching S, Cimenser A, Purdon PL, Brown EN, Kopell NJ | Proceedings of the National Academy of Sciences of the United States of America | 21149695 | Proc Natl Acad Sci U S A | 2010 Dec 28 |
Thalamocortical mechanisms for the anteriorization of α rhythms during propofol-induced unconsciousness. | Vijayan S, Ching S, Purdon PL, Brown EN, Kopell NJ | The Journal of neuroscience : the official journal of the Society for Neuroscience | 23825412 | J Neurosci | 2013 Jul 3 |
A closed-loop anesthetic delivery system for real-time control of burst suppression. | Liberman MY, Ching S, Chemali J, Brown EN | Journal of neural engineering | 23744607 | J Neural Eng | 2013 Aug |
A spatially-regularized dynamic source localization algorithm for EEG. | Pirondini E, Babadi B, Lamus C, Brown EN, Purdon PL | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 23367479 | Annu Int Conf IEEE Eng Med Biol Soc | 2012 |
Electroencephalogram signatures of loss and recovery of consciousness from propofol. | Purdon PL, Pierce ET, Mukamel EA, Prerau MJ, Walsh JL, Wong KF, Salazar-Gomez AF, Harrell PG, Sampson AL, Cimenser A, Ching S, Kopell NJ, Tavares-Stoeckel C, Habeeb K, Merhar R, Brown EN | Proceedings of the National Academy of Sciences of the United States of America | 23487781 | Proc Natl Acad Sci U S A | 2013 Mar 19 |
Differential involvement of excitatory and inhibitory neurons of cat motor cortex in coincident spike activity related to behavioral context. | Putrino D, Brown EN, Mastaglia FL, Ghosh S | The Journal of neuroscience : the official journal of the Society for Neuroscience | 20534853 | J Neurosci | 2010 Jun 9 |
A state-space model of the burst suppression ratio. | Chemali JJ, Wong KF, Solt K, Brown EN | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 22254587 | Annu Int Conf IEEE Eng Med Biol Soc | 2011 |
STATE-SPACE SOLUTIONS TO THE DYNAMIC MAGNETOENCEPHALOGRAPHY INVERSE PROBLEM USING HIGH PERFORMANCE COMPUTING. | Long CJ, Purdon PL, Temereanca S, Desai NU, Hämäläinen MS, Brown EN | The annals of applied statistics | 22081780 | Ann Appl Stat | 2011 Jun 1 |
General anesthesia and altered states of arousal: a systems neuroscience analysis. | Brown EN, Purdon PL, Van Dort CJ | Annual review of neuroscience | 21513454 | Annu Rev Neurosci | 2011 |
Likelihood methods for point processes with refractoriness. | Citi L, Ba D, Brown EN, Barbieri R | Neural computation | 24206384 | Neural Comput | 2014 Feb |
Interaction between Heart Rate Variability and Respiration in Preterm Infants. | Indic P, Salisbury E, Paydarfar D, Brown E, Barbieri R | Computers in cardiology | 20333264 | Comput Cardiol | 2008 Sep |
Discrete- and continuous-time probabilistic models and algorithms for inferring neuronal UP and DOWN states. | Chen Z, Vijayan S, Barbieri R, Wilson MA, Brown EN | Neural computation | 19323637 | Neural Comput | 2009 Jul |
Trial outcome and associative learning signals in the monkey hippocampus. | Wirth S, Avsar E, Chiu CC, Sharma V, Smith AC, Brown E, Suzuki WA | Neuron | 19324001 | Neuron | 2009 Mar 26 |
Potential network mechanisms mediating electroencephalographic beta rhythm changes during propofol-induced paradoxical excitation. | McCarthy MM, Brown EN, Kopell N | The Journal of neuroscience : the official journal of the Society for Neuroscience | 19074022 | J Neurosci | 2008 Dec 10 |
A probabilistic framework for learning robust common spatial patterns. | Wu W, Chen Z, Gao S, Brown EN | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 19963618 | Annu Int Conf IEEE Eng Med Biol Soc | 2009 |
State-space algorithms for estimating spike rate functions. | Smith AC, Scalon JD, Wirth S, Yanike M, Suzuki WA, Brown EN | Computational intelligence and neuroscience | 19911062 | Comput Intell Neurosci | 2010 |
Human leg model predicts ankle muscle-tendon morphology, state, roles and energetics in walking. | Krishnaswamy P, Brown EN, Herr HM | PLoS computational biology | 21445231 | PLoS Comput Biol | 2011 Mar |
Deconvolution of serum cortisol levels by using compressed sensing. | Faghih RT, Dahleh MA, Adler GK, Klerman EB, Brown EN | PloS one | 24489656 | PLoS One | 2014 |
A real-time automated point-process method for the detection and correction of erroneous and ectopic heartbeats. | Citi L, Brown EN, Barbieri R | IEEE transactions on bio-medical engineering | 22875239 | IEEE Trans Biomed Eng | 2012 Oct |
Motor cortical networks for skilled movements have dynamic properties that are related to accurate reaching. | Putrino DF, Chen Z, Ghosh S, Brown EN | Neural plasticity | 22007332 | Neural Plast | 2011 |
Robust time-varying multivariate coherence estimation: application to electroencephalogram recordings during general anesthesia. | Wong KF, Mukamel EA, Salazar AF, Pierce ET, Harrell PG, Walsh JL, Sampson A, Brown EN, Purdon PL | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 22255393 | Annu Int Conf IEEE Eng Med Biol Soc | 2011 |
Neural population partitioning and a concurrent brain-machine interface for sequential motor function. | Shanechi MM, Hu RC, Powers M, Wornell GW, Brown EN, Williams ZM | Nature neuroscience | 23143511 | Nat Neurosci | 2012 Dec |
Point Process Heart Rate Variability Assessment during Sleep Deprivation. | Citi L, Klerman E, Brown E, Barbieri R | Computing in cardiology | 22517071 | Comput Cardiol (2010) | 2010 Dec 31 |
Encoding through patterns: regression tree-based neuronal population models. | Haslinger R, Pipa G, Lewis LD, Nikolić D, Williams Z, Brown E | Neural computation | 23607564 | Neural Comput | 2013 Aug |
Modulation depth estimation and variable selection in state-space models for neural interfaces. | Malik WQ, Hochberg LR, Donoghue JP, Brown EN | IEEE transactions on bio-medical engineering | 25265627 | IEEE Trans Biomed Eng | 2015 Feb |
A PK-PD model of ketamine-induced high-frequency oscillations. | Flores FJ, Ching S, Hartnack K, Fath AB, Purdon PL, Wilson MA, Brown EN | Journal of neural engineering | 26268223 | J Neural Eng | 2015 Oct |
Optogenetic activation of cholinergic neurons in the PPT or LDT induces REM sleep. | Van Dort CJ, Zachs DP, Kenny JD, Zheng S, Goldblum RR, Gelwan NA, Ramos DM, Nolan MA, Wang K, Weng FJ, Lin Y, Wilson MA, Brown EN | Proceedings of the National Academy of Sciences of the United States of America | 25548191 | Proc Natl Acad Sci U S A | 2015 Jan 13 |
Nitrous oxide-induced slow and delta oscillations. | Pavone KJ, Akeju O, Sampson AL, Ling K, Purdon PL, Brown EN | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology | 26118489 | Clin Neurophysiol | 2016 Jan |
Ageing delays emergence from general anaesthesia in rats by increasing anaesthetic sensitivity in the brain. | Chemali JJ, Kenny JD, Olutola O, Taylor NE, Kimchi EY, Purdon PL, Brown EN, Solt K | British journal of anaesthesia | 26174302 | Br J Anaesth | 2015 Jul |
The Role of Glutamatergic and Dopaminergic Neurons in the Periaqueductal Gray/Dorsal Raphe: Separating Analgesia and Anxiety. | Taylor NE, Pei J, Zhang J, Vlasov KY, Davis T, Taylor E, Weng FJ, Van Dort CJ, Solt K, Brown EN | eNeuro | 31058210 | eNeuro | 2019 Jan-Feb |
Cognitive Impairment Is Associated with Absolute Intraoperative Frontal α-Band Power but Not with Baseline α-Band Power: A Pilot Study. | Koch S, Feinkohl I, Chakravarty S, Windmann V, Lichtner G, Pischon T, Brown EN, Spies C, BioCog Study Group | Dementia and geriatric cognitive disorders | 31578031 | Dement Geriatr Cogn Disord | 2019 |
Application of dynamic point process models to cardiovascular control. | Barbieri R, Brown EN | Bio Systems | 18515000 | Biosystems | 2008 Jul-Aug |
The Fitzhugh-Nagumo model: Firing modes with time-varying parameters & parameter estimation. | Faghih RT, Savla K, Dahleh MA, Brown EN | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 21096631 | Annu Int Conf IEEE Eng Med Biol Soc | 2010 |
A differential autoregressive modeling approach within a point process framework for non-stationary heartbeat intervals analysis. | Chen Z, Purdon PL, Brown EN, Barbieri R | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 21096829 | Annu Int Conf IEEE Eng Med Biol Soc | 2010 |
Methylphenidate actively induces emergence from general anesthesia. | Solt K, Cotten JF, Cimenser A, Wong KF, Chemali JJ, Brown EN | Anesthesiology | 21934407 | Anesthesiology | 2011 Oct |
General anesthesia, sleep, and coma. | Brown EN, Lydic R, Schiff ND | The New England journal of medicine | 21190458 | N Engl J Med | 2010 Dec 30 |
Dynamic assessment of baroreflex control of heart rate during induction of propofol anesthesia using a point process method. | Chen Z, Purdon PL, Harrell G, Pierce ET, Walsh J, Brown EN, Barbieri R | Annals of biomedical engineering | 20945159 | Ann Biomed Eng | 2011 Jan |
A hierarchical Bayesian approach for learning sparse spatio-temporal decompositions of multichannel EEG. | Wu W, Chen Z, Gao S, Brown EN | NeuroImage | 21420499 | Neuroimage | 2011 Jun 15 |
Real-time segmentation and tracking of brain metabolic state in ICU EEG recordings of burst suppression. | Westover MB, Ching S, Shafi MM, Cash SS, Brown EN | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 24111383 | Annu Int Conf IEEE Eng Med Biol Soc | 2013 |
Transductive neural decoding for unsorted neuronal spikes of rat hippocampus. | Chen Z, Kloosterman F, Layton S, Wilson MA | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 23366139 | Annu Int Conf IEEE Eng Med Biol Soc | 2012 |
A fast iterative greedy algorithm for MEG source localization. | Obregon-Henao G, Babadi B, Lamus C, Brown EN, Purdon PL | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 23367478 | Annu Int Conf IEEE Eng Med Biol Soc | 2012 |
Point-process analysis of neural spiking activity of muscle spindles recorded from thin-film longitudinal intrafascicular electrodes. | Citi L, Djilas M, Azevedo-Coste C, Yoshida K, Brown EN, Barbieri R | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 22254803 | Annu Int Conf IEEE Eng Med Biol Soc | 2011 |
Static and dynamic autonomic response with increasing nausea perception. | LaCount LT, Barbieri R, Park K, Kim J, Brown EN, Kuo B, Napadow V | Aviation, space, and environmental medicine | 21485400 | Aviat Space Environ Med | 2011 Apr |
Rapid fragmentation of neuronal networks at the onset of propofol-induced unconsciousness. | Lewis LD, Weiner VS, Mukamel EA, Donoghue JA, Eskandar EN, Madsen JR, Anderson WS, Hochberg LR, Cash SS, Brown EN, Purdon PL | Proceedings of the National Academy of Sciences of the United States of America | 23129622 | Proc Natl Acad Sci U S A | 2012 Dec 4 |
Modeling the dynamical effects of anesthesia on brain circuits. | Ching S, Brown EN | Current opinion in neurobiology | 24457211 | Curr Opin Neurobiol | 2014 Apr |
Burst suppression probability algorithms: state-space methods for tracking EEG burst suppression. | Chemali J, Ching S, Purdon PL, Solt K, Brown EN | Journal of neural engineering | 24018288 | J Neural Eng | 2013 Oct |
A brain-machine interface for control of medically-induced coma. | Shanechi MM, Chemali JJ, Liberman M, Solt K, Brown EN | PLoS computational biology | 24204231 | PLoS Comput Biol | 2013 Oct |
Real-time segmentation of burst suppression patterns in critical care EEG monitoring. | Brandon Westover M, Shafi MM, Ching S, Chemali JJ, Purdon PL, Cash SS, Brown EN | Journal of neuroscience methods | 23891828 | J Neurosci Methods | 2013 Sep 30 |
The aging brain and anesthesia. | Brown EN, Purdon PL | Current opinion in anaesthesiology | 23820102 | Curr Opin Anaesthesiol | 2013 Aug |
Understanding the TXA seizure connection. | Schwinn DA, Mackensen GB, Brown EN | The Journal of clinical investigation | 23187134 | J Clin Invest | 2012 Dec |
Activation of D1 dopamine receptors induces emergence from isoflurane general anesthesia. | Taylor NE, Chemali JJ, Brown EN, Solt K | Anesthesiology | 23221866 | Anesthesiology | 2013 Jan |
A transition in brain state during propofol-induced unconsciousness. | Mukamel EA, Pirondini E, Babadi B, Wong KF, Pierce ET, Harrell PG, Walsh JL, Salazar-Gomez AF, Cash SS, Eskandar EN, Weiner VS, Brown EN, Purdon PL | The Journal of neuroscience : the official journal of the Society for Neuroscience | 24431442 | J Neurosci | 2014 Jan 15 |
Electroencephalogram signatures of ketamine anesthesia-induced unconsciousness. | Akeju O, Song AH, Hamilos AE, Pavone KJ, Flores FJ, Brown EN, Purdon PL | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology | 27178861 | Clin Neurophysiol | 2016 Jun |
Measuring the signal-to-noise ratio of a neuron. | Czanner G, Sarma SV, Ba D, Eden UT, Wu W, Eskandar E, Lim HH, Temereanca S, Suzuki WA, Brown EN | Proceedings of the National Academy of Sciences of the United States of America | 25995363 | Proc Natl Acad Sci U S A | 2015 Jun 9 |
Reference-free removal of EEG-fMRI ballistocardiogram artifacts with harmonic regression. | Krishnaswamy P, Bonmassar G, Poulsen C, Pierce ET, Purdon PL, Brown EN | NeuroImage | 26151100 | Neuroimage | 2016 Mar |
Electroencephalographic markers of brain development during sevoflurane anaesthesia in children up to 3 years old. | Cornelissen L, Kim SE, Lee JM, Brown EN, Purdon PL, Berde CB | British journal of anaesthesia | 29793594 | Br J Anaesth | 2018 Jun |
Left-Lateralized Contributions of Saccades to Cortical Activity During a One-Back Word Recognition Task. | Chang YC, Khan S, Taulu S, Kuperberg G, Brown EN, Hämäläinen MS, Temereanca S | Frontiers in neural circuits | 29867372 | Front Neural Circuits | 2018 |
Simultaneous electroencephalography and functional magnetic resonance imaging of general anesthesia. | Purdon PL, Pierce ET, Bonmassar G, Walsh J, Harrell PG, Kwo J, Deschler D, Barlow M, Merhar RC, Lamus C, Mullaly CM, Sullivan M, Maginnis S, Skoniecki D, Higgins HA, Brown EN | Annals of the New York Academy of Sciences | 19351356 | Ann N Y Acad Sci | 2009 Mar |
Characterizing nonlinear heartbeat dynamics within a point process framework. | Chen Z, Brown EN, Barbieri R | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 19163282 | Annu Int Conf IEEE Eng Med Biol Soc | 2008 |
Linear and nonlinear quantification of respiratory sinus arrhythmia during propofol general anesthesia. | Chen Z, Purdon PL, Pierce ET, Harrell G, Walsh J, Salazar AF, Tavares CL, Brown EN, Barbieri R | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 19963899 | Annu Int Conf IEEE Eng Med Biol Soc | 2009 |
Mapping of visual receptive fields by tomographic reconstruction. | Pipa G, Chen Z, Neuenschwander S, Lima B, Brown EN | Neural computation | 22734491 | Neural Comput | 2012 Oct |
Broad range of neural dynamics from a time-varying FitzHugh-Nagumo model and its spiking threshold estimation. | Faghih RT, Savla K, Dahleh MA, Brown EN | IEEE transactions on bio-medical engineering | 22186931 | IEEE Trans Biomed Eng | 2012 Mar |
Correcting for serial dependence in studies of respiratory dynamics. | Gong JJ, Wong KF, Cotten JF, Solt K, Brown EN | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 22254658 | Annu Int Conf IEEE Eng Med Biol Soc | 2011 |
Bayesian analysis of trinomial data in behavioral experiments and its application to human studies of general anesthesia. | Wong KF, Smith AC, Pierce ET, Harrell PG, Walsh JL, Salazar AF, Tavares CL, Cimenser A, Prerau MJ, Mukamel EA, Sampson A, Purdon PL, Brown EN | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 22255388 | Annu Int Conf IEEE Eng Med Biol Soc | 2011 |
Uncovering spatial topology represented by rat hippocampal population neuronal codes. | Chen Z, Kloosterman F, Brown EN, Wilson MA | Journal of computational neuroscience | 22307459 | J Comput Neurosci | 2012 Oct |
Point process time-frequency analysis of dynamic respiratory patterns during meditation practice. | Kodituwakku S, Lazar SW, Indic P, Chen Z, Brown EN, Barbieri R | Medical & biological engineering & computing | 22350435 | Med Biol Eng Comput | 2012 Mar |
Using point process models to compare neural spiking activity in the subthalamic nucleus of Parkinson's patients and a healthy primate. | Sarma SV, Eden UT, Cheng ML, Williams ZM, Hu R, Eskandar E, Brown EN | IEEE transactions on bio-medical engineering | 20172804 | IEEE Trans Biomed Eng | 2010 Jun |
Eye movements modulate the spatiotemporal dynamics of word processing. | Temereanca S, Hämäläinen MS, Kuperberg GR, Stufflebeam SM, Halgren E, Brown EN | The Journal of neuroscience : the official journal of the Society for Neuroscience | 22457496 | J Neurosci | 2012 Mar 28 |
Fungicidal drugs induce a common oxidative-damage cellular death pathway. | Belenky P, Camacho D, Collins JJ | Cell reports | 23416050 | Cell Rep | 2013 Feb 21 |
Metabolite-enabled eradication of bacterial persisters by aminoglycosides. | Allison KR, Brynildsen MP, Collins JJ | Nature | 21562562 | Nature | 2011 May 12 |
Tracking, tuning, and terminating microbial physiology using synthetic riboregulators. | Callura JM, Dwyer DJ, Isaacs FJ, Cantor CR, Collins JJ | Proceedings of the National Academy of Sciences of the United States of America | 20713708 | Proc Natl Acad Sci U S A | 2010 Sep 7 |
Role of reactive oxygen species in antibiotic action and resistance. | Dwyer DJ, Kohanski MA, Collins JJ | Current opinion in microbiology | 19647477 | Curr Opin Microbiol | 2009 Oct |
Networking opportunities for bacteria. | Dwyer DJ, Kohanski MA, Collins JJ | Cell | 19109881 | Cell | 2008 Dec 26 |
Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics. | Foti JJ, Devadoss B, Winkler JA, Collins JJ, Walker GC | Science (New York, N.Y.) | 22517853 | Science | 2012 Apr 20 |
Bacteria as control engineers. | Allison KR, Collins JJ | Molecular cell | 21211717 | Mol Cell | 2011 Jan 7 |
Synthetic biology: applications come of age. | Khalil AS, Collins JJ | Nature reviews. Genetics | 20395970 | Nat Rev Genet | 2010 May |
A role for the bacterial GATC methylome in antibiotic stress survival. | Cohen NR, Ross CA, Jain S, Shapiro RS, Gutierrez A, Belenky P, Li H, Collins JJ | Nature genetics | 26998690 | Nat Genet | 2016 May |
Antibiotic efficacy is linked to bacterial cellular respiration. | Lobritz MA, Belenky P, Porter CB, Gutierrez A, Yang JH, Schwarz EG, Dwyer DJ, Khalil AS, Collins JJ | Proceedings of the National Academy of Sciences of the United States of America | 26100898 | Proc Natl Acad Sci U S A | 2015 Jul 7 |
Next-generation synthetic gene networks. | Lu TK, Khalil AS, Collins JJ | Nature biotechnology | 20010597 | Nat Biotechnol | 2009 Dec |
Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis. | Kohanski MA, DePristo MA, Collins JJ | Molecular cell | 20159551 | Mol Cell | 2010 Feb 12 |
Heterogeneous bacterial persisters and engineering approaches to eliminate them. | Allison KR, Brynildsen MP, Collins JJ | Current opinion in microbiology | 21937262 | Curr Opin Microbiol | 2011 Oct |
Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death. | Kohanski MA, Dwyer DJ, Wierzbowski J, Cottarel G, Collins JJ | Cell | 19013277 | Cell | 2008 Nov 14 |
Functional characterization of bacterial sRNAs using a network biology approach. | Modi SR, Camacho DM, Kohanski MA, Walker GC, Collins JJ | Proceedings of the National Academy of Sciences of the United States of America | 21876160 | Proc Natl Acad Sci U S A | 2011 Sep 13 |
Bacterial charity work leads to population-wide resistance. | Lee HH, Molla MN, Cantor CR, Collins JJ | Nature | 20811456 | Nature | 2010 Sep 2 |
Microbial environments confound antibiotic efficacy. | Lee HH, Collins JJ | Nature chemical biology | 22173343 | Nat Chem Biol | 2011 Dec 15 |
Microbial persistence and the road to drug resistance. | Cohen NR, Lobritz MA, Collins JJ | Cell host & microbe | 23768488 | Cell Host Microbe | 2013 Jun 12 |
Wisdom of crowds for robust gene network inference. | Marbach D, Costello JC, Küffner R, Vega NM, Prill RJ, Camacho DM, Allison KR, DREAM5 Consortium, Kellis M, Collins JJ, Stolovitzky G | Nature methods | 22796662 | Nat Methods | 2012 Jul 15 |
A network biology approach to aging in yeast. | Lorenz DR, Cantor CR, Collins JJ | Proceedings of the National Academy of Sciences of the United States of America | 19164565 | Proc Natl Acad Sci U S A | 2009 Jan 27 |
Tunable signal processing in synthetic MAP kinase cascades. | O'Shaughnessy EC, Palani S, Collins JJ, Sarkar CA | Cell | 21215374 | Cell | 2011 Jan 7 |
Central role for RNase YbeY in Hfq-dependent and Hfq-independent small-RNA regulation in bacteria. | Pandey SP, Winkler JA, Li H, Camacho DM, Collins JJ, Walker GC | BMC genomics | 24511998 | BMC Genomics | 2014 Feb 11 |
Antibiotic-induced bacterial cell death exhibits physiological and biochemical hallmarks of apoptosis. | Dwyer DJ, Camacho DM, Kohanski MA, Callura JM, Collins JJ | Molecular cell | 22633370 | Mol Cell | 2012 Jun 8 |
Bactericidal Antibiotics Induce Toxic Metabolic Perturbations that Lead to Cellular Damage. | Belenky P, Ye JD, Porter CB, Cohen NR, Lobritz MA, Ferrante T, Jain S, Korry BJ, Schwarz EG, Walker GC, Collins JJ | Cell reports | 26565910 | Cell Rep | 2015 Nov 3 |
How antibiotics kill bacteria: from targets to networks. | Kohanski MA, Dwyer DJ, Collins JJ | Nature reviews. Microbiology | 20440275 | Nat Rev Microbiol | 2010 Jun |
Antibiotic treatment expands the resistance reservoir and ecological network of the phage metagenome. | Modi SR, Lee HH, Spina CS, Collins JJ | Nature | 23748443 | Nature | 2013 Jul 11 |
Tunable protein degradation in bacteria. | Cameron DE, Collins JJ | Nature biotechnology | 25402616 | Nat Biotechnol | 2014 Dec |
Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production. | Brynildsen MP, Winkler JA, Spina CS, MacDonald IC, Collins JJ | Nature biotechnology | 23292609 | Nat Biotechnol | 2013 Feb |
Iterative plug-and-play methodology for constructing and modifying synthetic gene networks. | Litcofsky KD, Afeyan RB, Krom RJ, Khalil AS, Collins JJ | Nature methods | 23042452 | Nat Methods | 2012 Nov |
Diversity-based, model-guided construction of synthetic gene networks with predicted functions. | Ellis T, Wang X, Collins JJ | Nature biotechnology | 19377462 | Nat Biotechnol | 2009 May |
Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli. | Davies BW, Kohanski MA, Simmons LA, Winkler JA, Collins JJ, Walker GC | Molecular cell | 20005847 | Mol Cell | 2009 Dec 11 |
Synthetic gene networks that count. | Friedland AE, Lu TK, Wang X, Shi D, Church G, Collins JJ | Science (New York, N.Y.) | 19478183 | Science | 2009 May 29 |
Signaling-mediated bacterial persister formation. | Vega NM, Allison KR, Khalil AS, Collins JJ | Nature chemical biology | 22426114 | Nat Chem Biol | 2012 Mar 18 |
Genetic switchboard for synthetic biology applications. | Callura JM, Cantor CR, Collins JJ | Proceedings of the National Academy of Sciences of the United States of America | 22454498 | Proc Natl Acad Sci U S A | 2012 Apr 10 |
Gifts and influence: Conflict of interest policies and prescribing of psychotropic medications in the United States. | King M, Bearman PS | Social science & medicine (1982) | 27856120 | Soc Sci Med | 2017 Jan |
Medical school gift restriction policies and physician prescribing of newly marketed psychotropic medications: difference-in-differences analysis. | King M, Essick C, Bearman P, Ross JS | BMJ (Clinical research ed.) | 23372175 | BMJ | 2013 Jan 30 |
Estimated autism risk and older reproductive age. | King MD, Fountain C, Dakhlallah D, Bearman PS | American journal of public health | 19608957 | Am J Public Health | 2009 Sep |
Authors' response to: cohort effects explain the increase in autism diagnosis: an identifiability problem of the age-period-cohort model. | Keyes KM, Susser E, Cheslack-Postava K, Fountain C, Liu K, Bearman PS | International journal of epidemiology | 25361588 | Int J Epidemiol | 2014 Dec |
Socioeconomic Status and the Increased Prevalence of Autism in California. | King MD, Bearman PS | American sociological review | 21547238 | Am Sociol Rev | 2011 Apr 1 |
Focal Points, Endogenous Processes, and Exogenous Shocks in the Autism Epidemic. | Liu K, Bearman PS | Sociological methods & research | 26166907 | Sociol Methods Res | 2015 May 1 |
Age of diagnosis for autism: individual and community factors across 10 birth cohorts. | Fountain C, King MD, Bearman PS | Journal of epidemiology and community health | 20974836 | J Epidemiol Community Health | 2011 Jun |
The spatial structure of autism in California, 1993-2001. | Mazumdar S, King M, Liu KY, Zerubavel N, Bearman P | Health & place | 20097113 | Health Place | 2010 May |
The disappearing seasonality of autism conceptions in California. | Mazumdar S, Liu KY, Susser E, Bearman P | PloS one | 22859972 | PLoS One | 2012 |
Six developmental trajectories characterize children with autism. | Fountain C, Winter AS, Bearman PS | Pediatrics | 22473372 | Pediatrics | 2012 May |
Diagnostic change and the increased prevalence of autism. | King M, Bearman P | International journal of epidemiology | 19737791 | Int J Epidemiol | 2009 Oct |
The Temporal Structure of Scientific Consensus Formation. | Shwed U, Bearman PS | American sociological review | 21886269 | Am Sociol Rev | 2010 Dec 1 |
Closely spaced pregnancies are associated with increased odds of autism in California sibling births. | Cheslack-Postava K, Liu K, Bearman PS | Pediatrics | 21220394 | Pediatrics | 2011 Feb |
Social influence and the autism epidemic. | Liu KY, King M, Bearman PS | AJS; American journal of sociology | 20503647 | AJS | 2010 Mar |
Estimated autism risk, older reproductive age, and parameterization. | Durkin MS, Maenner MJ, Newschaffer CJ | American journal of public health | 20075308 | Am J Public Health | 2010 Mar |
Just-so Stories: Vaccines, Autism, and the Single-bullet Disorder. | Bearman P | Social psychology quarterly | 20721312 | Soc Psychol Q | 2009 Jun |
Cohort effects explain the increase in autism diagnosis among children born from 1992 to 2003 in California. | Keyes KM, Susser E, Cheslack-Postava K, Fountain C, Liu K, Bearman PS | International journal of epidemiology | 22253308 | Int J Epidemiol | 2012 Apr |
Association of assisted reproductive technology (ART) treatment and parental infertility diagnosis with autism in ART-conceived children. | Kissin DM, Zhang Y, Boulet SL, Fountain C, Bearman P, Schieve L, Yeargin-Allsopp M, Jamieson DJ | Human reproduction (Oxford, England) | 25518976 | Hum Reprod | 2015 Feb |
Can Sibling Sex Ratios Be Used as a Valid Test for the Prenatal Androgen Hypothesis of Autism Spectrum Disorders? | Cheslack-Postava K, Susser E, Liu K, Bearman PS | PloS one | 26495967 | PLoS One | 2015 |
Reply: CDC analysis of ICSI/autism: association is not causation. | Kissin DM, Zhang Y, Boulet SL, Fountain C, Bearman P, Schieve L, Yeargin-Allsopp M, Jamieson DJ | Human reproduction (Oxford, England) | 25976658 | Hum Reprod | 2015 Jul |
Does Autism Diagnosis Age or Symptom Severity Differ Among Children According to Whether Assisted Reproductive Technology was Used to Achieve Pregnancy? | Schieve LA, Fountain C, Boulet SL, Yeargin-Allsopp M, Kissin DM, Jamieson DJ, Rice C, Bearman P | Journal of autism and developmental disorders | 25997596 | J Autism Dev Disord | 2015 Sep |
Social demographic change and autism. | Liu K, Zerubavel N, Bearman P | Demography | 20608100 | Demography | 2010 May |
Spatial clusters of autism births and diagnoses point to contextual drivers of increased prevalence. | Mazumdar S, Winter A, Liu KY, Bearman P | Social science & medicine (1982) | 23267775 | Soc Sci Med | 2013 Oct |
Risk as Social Context: Immigration Policy and Autism in California. | Fountain C, Bearman P | Sociological forum (Randolph, N.J.) | 21643443 | Sociol Forum (Randolph N J) | 2011 Jun 1 |
Association between assisted reproductive technology conception and autism in California, 1997-2007. | Fountain C, Zhang Y, Kissin DM, Schieve LA, Jamieson DJ, Rice C, Bearman P | American journal of public health | 25790396 | Am J Public Health | 2015 May |
Using TIRF microscopy to quantify and confirm efficient mass transfer at the substrate surface of the chemistrode. | Chen D, Du W, Ismagilov RF | New journal of physics | 19809528 | New J Phys | 2009 |
SlipChip. | Du W, Li L, Nichols KP, Ismagilov RF | Lab on a chip | 19636458 | Lab Chip | 2009 Aug 21 |
Plug-based microfluidics with defined surface chemistry to miniaturize and control aggregation of amyloidogenic peptides. | Meier M, Kennedy-Darling J, Choi SH, Norstrom EM, Sisodia SS, Ismagilov RF | Angewandte Chemie (International ed. in English) | 19152390 | Angew Chem Int Ed Engl | 2009 |
Multiparameter screening on SlipChip used for nanoliter protein crystallization combining free interface diffusion and microbatch methods. | Li L, Du W, Ismagilov RF | Journal of the American Chemical Society | 20000709 | J Am Chem Soc | 2010 Jan 13 |
Measuring fate and rate of single-molecule competition of amplification and restriction digestion, and its use for rapid genotyping tested with hepatitis C viral RNA. | Sun B, Rodriguez-Manzano J, Selck DA, Khorosheva E, Karymov MA, Ismagilov RF | Angewandte Chemie (International ed. in English) | 24889060 | Angew Chem Int Ed Engl | 2014 Jul 28 |
Multiplexed quantification of nucleic acids with large dynamic range using multivolume digital RT-PCR on a rotational SlipChip tested with HIV and hepatitis C viral load. | Shen F, Sun B, Kreutz JE, Davydova EK, Du W, Reddy PL, Joseph LJ, Ismagilov RF | Journal of the American Chemical Society | 21995644 | J Am Chem Soc | 2011 Nov 9 |
Chemical analog-to-digital signal conversion based on robust threshold chemistry and its evaluation in the context of microfluidics-based quantitative assays. | Huynh T, Sun B, Li L, Nichols KP, Koyner JL, Ismagilov RF | Journal of the American Chemical Society | 24060606 | J Am Chem Soc | 2013 Oct 2 |
Increased robustness of single-molecule counting with microfluidics, digital isothermal amplification, and a mobile phone versus real-time kinetic measurements. | Selck DA, Karymov MA, Sun B, Ismagilov RF | Analytical chemistry | 24199852 | Anal Chem | 2013 Nov 19 |
Nanoliter multiplex PCR arrays on a SlipChip. | Shen F, Du W, Davydova EK, Karymov MA, Pandey J, Ismagilov RF | Analytical chemistry | 20446698 | Anal Chem | 2010 Jun 1 |
Digital isothermal quantification of nucleic acids via simultaneous chemical initiation of recombinase polymerase amplification reactions on SlipChip. | Shen F, Davydova EK, Du W, Kreutz JE, Piepenburg O, Ismagilov RF | Analytical chemistry | 21476587 | Anal Chem | 2011 May 1 |
Complex function by design using spatially pre-structured synthetic microbial communities: degradation of pentachlorophenol in the presence of Hg(ii). | Kim HJ, Du W, Ismagilov RF | Integrative biology : quantitative biosciences from nano to macro | 20717565 | Integr Biol (Camb) | 2011 Feb |
Chemical stimulation of the Arabidopsis thaliana root using multi-laminar flow on a microfluidic chip. | Meier M, Lucchetta EM, Ismagilov RF | Lab on a chip | 20544086 | Lab Chip | 2010 Aug 21 |
Detecting bacteria and determining their susceptibility to antibiotics by stochastic confinement in nanoliter droplets using plug-based microfluidics. | Boedicker JQ, Li L, Kline TR, Ismagilov RF | Lab on a chip | 18651067 | Lab Chip | 2008 Aug |
Isolation, incubation, and parallel functional testing and identification by FISH of rare microbial single-copy cells from multi-species mixtures using the combination of chemistrode and stochastic confinement. | Liu W, Kim HJ, Lucchetta EM, Du W, Ismagilov RF | Lab on a chip | 19606291 | Lab Chip | 2009 Aug 7 |
Theoretical design and analysis of multivolume digital assays with wide dynamic range validated experimentally with microfluidic digital PCR. | Kreutz JE, Munson T, Huynh T, Shen F, Du W, Ismagilov RF | Analytical chemistry | 21981344 | Anal Chem | 2011 Nov 1 |
Mechanistic evaluation of the pros and cons of digital RT-LAMP for HIV-1 viral load quantification on a microfluidic device and improved efficiency via a two-step digital protocol. | Sun B, Shen F, McCalla SE, Kreutz JE, Karymov MA, Ismagilov RF | Analytical chemistry | 23324061 | Anal Chem | 2013 Feb 5 |
Microfluidic confinement of single cells of bacteria in small volumes initiates high-density behavior of quorum sensing and growth and reveals its variability. | Boedicker JQ, Vincent ME, Ismagilov RF | Angewandte Chemie (International ed. in English) | 19565587 | Angew Chem Int Ed Engl | 2009 |
Spatial localization of bacteria controls coagulation of human blood by 'quorum acting'. | Kastrup CJ, Boedicker JQ, Pomerantsev AP, Moayeri M, Bian Y, Pompano RR, Kline TR, Sylvestre P, Shen F, Leppla SH, Tang WJ, Ismagilov RF | Nature chemical biology | 19031531 | Nat Chem Biol | 2008 Dec |
Microfluidic stochastic confinement enhances analysis of rare cells by isolating cells and creating high density environments for control of diffusible signals. | Vincent ME, Liu W, Haney EB, Ismagilov RF | Chemical Society reviews | 20179819 | Chem Soc Rev | 2010 Mar |
Dead-end filling of SlipChip evaluated theoretically and experimentally as a function of the surface chemistry and the gap size between the plates for lubricated and dry SlipChips. | Li L, Karymov MA, Nichols KP, Ismagilov RF | Langmuir : the ACS journal of surfaces and colloids | 20575548 | Langmuir | 2010 Jul 20 |
Lack of correlation between reaction speed and analytical sensitivity in isothermal amplification reveals the value of digital methods for optimization: validation using digital real-time RT-LAMP. | Khorosheva EM, Karymov MA, Selck DA, Ismagilov RF | Nucleic acids research | 26358811 | Nucleic Acids Res | 2016 Jan 29 |
Conceptual and Experimental Tools to Understand Spatial Effects and Transport Phenomena in Nonlinear Biochemical Networks Illustrated with Patchy Switching. | Pompano RR, Chiang AH, Kastrup CJ, Ismagilov RF | Annual review of biochemistry | 28654324 | Annu Rev Biochem | 2017 Jun 20 |
SlipChip for immunoassays in nanoliter volumes. | Liu W, Chen D, Du W, Nichols KP, Ismagilov RF | Analytical chemistry | 20334360 | Anal Chem | 2010 Apr 15 |
Defined spatial structure stabilizes a synthetic multispecies bacterial community. | Kim HJ, Boedicker JQ, Choi JW, Ismagilov RF | Proceedings of the National Academy of Sciences of the United States of America | 19011107 | Proc Natl Acad Sci U S A | 2008 Nov 25 |
The chemistrode: a droplet-based microfluidic device for stimulation and recording with high temporal, spatial, and chemical resolution. | Chen D, Du W, Liu Y, Liu W, Kuznetsov A, Mendez FE, Philipson LH, Ismagilov RF | Proceedings of the National Academy of Sciences of the United States of America | 18974218 | Proc Natl Acad Sci U S A | 2008 Nov 4 |
Microfluidics using spatially defined arrays of droplets in one, two, and three dimensions. | Pompano RR, Liu W, Du W, Ismagilov RF | Annual review of analytical chemistry (Palo Alto, Calif.) | 21370983 | Annu Rev Anal Chem (Palo Alto Calif) | 2011 |
Long-term dynamics of CA1 hippocampal place codes. | Ziv Y, Burns LD, Cocker ED, Hamel EO, Ghosh KK, Kitch LJ, El Gamal A, Schnitzer MJ | Nature neuroscience | 23396101 | Nat Neurosci | 2013 Mar |
Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation. | Savall J, Ho ETW, Huang C, Maxey JR, Schnitzer MJ | Nature methods | 26005812 | Nat Methods | 2015 Jul |
Estimation theoretic measure of resolution for stochastic localization microscopy. | Fitzgerald JE, Lu J, Schnitzer MJ | Physical review letters | 23006110 | Phys Rev Lett | 2012 Jul 27 |
Symmetries in stimulus statistics shape the form of visual motion estimators. | Fitzgerald JE, Katsov AY, Clandinin TR, Schnitzer MJ | Proceedings of the National Academy of Sciences of the United States of America | 21768376 | Proc Natl Acad Sci U S A | 2011 Aug 2 |
Engineering approaches to illuminating brain structure and dynamics. | Deisseroth K, Schnitzer MJ | Neuron | 24183010 | Neuron | 2013 Oct 30 |
Imaging neuronal populations in behaving rodents: paradigms for studying neural circuits underlying behavior in the mammalian cortex. | Chen JL, Andermann ML, Keck T, Xu NL, Ziv Y | The Journal of neuroscience : the official journal of the Society for Neuroscience | 24198355 | J Neurosci | 2013 Nov 6 |
Imaging neural spiking in brain tissue using FRET-opsin protein voltage sensors. | Gong Y, Wagner MJ, Zhong Li J, Schnitzer MJ | Nature communications | 24755708 | Nat Commun | 2014 Apr 22 |
High-speed recording of neural spikes in awake mice and flies with a fluorescent voltage sensor. | Gong Y, Huang C, Li JZ, Grewe BF, Zhang Y, Eismann S, Schnitzer MJ | Science (New York, N.Y.) | 26586188 | Science | 2015 Dec 11 |
Advances in light microscopy for neuroscience. | Wilt BA, Burns LD, Wei Ho ET, Ghosh KK, Mukamel EA, Schnitzer MJ | Annual review of neuroscience | 19555292 | Annu Rev Neurosci | 2009 |
The evolving capabilities of rhodopsin-based genetically encoded voltage indicators. | Gong Y | Current opinion in chemical biology | 26143170 | Curr Opin Chem Biol | 2015 Aug |
Differences in neural circuitry guiding behavioral responses to polarized light presented to either the dorsal or ventral retina in Drosophila. | Velez MM, Gohl D, Clandinin TR, Wernet MF | Journal of neurogenetics | 24912584 | J Neurogenet | 2014 Sep-Dec |
Modular use of peripheral input channels tunes motion-detecting circuitry. | Silies M, Gohl DM, Fisher YE, Freifeld L, Clark DA, Clandinin TR | Neuron | 23849199 | Neuron | 2013 Jul 10 |
Mapping and cracking sensorimotor circuits in genetic model organisms. | Clark DA, Freifeld L, Clandinin TR | Neuron | 23719159 | Neuron | 2013 May 22 |
GABAergic lateral interactions tune the early stages of visual processing in Drosophila. | Freifeld L, Clark DA, Schnitzer MJ, Horowitz MA, Clandinin TR | Neuron | 23791198 | Neuron | 2013 Jun 19 |
A versatile in vivo system for directed dissection of gene expression patterns. | Gohl DM, Silies MA, Gao XJ, Bhalerao S, Luongo FJ, Lin CC, Potter CJ, Clandinin TR | Nature methods | 21473015 | Nat Methods | 2011 Mar |
Genetic dissection reveals two separate retinal substrates for polarization vision in Drosophila. | Wernet MF, Velez MM, Clark DA, Baumann-Klausener F, Brown JR, Klovstad M, Labhart T, Clandinin TR | Current biology : CB | 22177904 | Curr Biol | 2012 Jan 10 |
Defining the computational structure of the motion detector in Drosophila. | Clark DA, Bursztyn L, Horowitz MA, Schnitzer MJ, Clandinin TR | Neuron | 21689602 | Neuron | 2011 Jun 23 |
Processing properties of ON and OFF pathways for Drosophila motion detection. | Behnia R, Clark DA, Carter AG, Clandinin TR, Desplan C | Nature | 25043016 | Nature | 2014 Aug 28 |
Loom-sensitive neurons link computation to action in the Drosophila visual system. | de Vries SE, Clandinin TR | Current biology : CB | 22305754 | Curr Biol | 2012 Mar 6 |
A Drosophila toolkit for the visualization and quantification of viral replication launched from transgenic genomes. | Wernet MF, Klovstad M, Clandinin TR | PloS one | 25386852 | PLoS One | 2014 |
Dynamic structure of locomotor behavior in walking fruit flies. | Katsov AY, Freifeld L, Horowitz M, Kuehn S, Clandinin TR | eLife | 28742018 | Elife | 2017 Jul 25 |
Walking Drosophila align with the e-vector of linearly polarized light through directed modulation of angular acceleration. | Velez MM, Wernet MF, Clark DA, Clandinin TR | Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology | 24810784 | J Comp Physiol A Neuroethol Sens Neural Behav Physiol | 2014 Jun |
Motion processing streams in Drosophila are behaviorally specialized. | Katsov AY, Clandinin TR | Neuron | 18667159 | Neuron | 2008 Jul 31 |
Specific kinematics and motor-related neurons for aversive chemotaxis in Drosophila. | Gao XJ, Potter CJ, Gohl DM, Silies M, Katsov AY, Clandinin TR, Luo L | Current biology : CB | 23770185 | Curr Biol | 2013 Jul 8 |
Large-scale mapping of transposable element insertion sites using digital encoding of sample identity. | Gohl DM, Freifeld L, Silies M, Hwa JJ, Horowitz M, Clandinin TR | Genetics | 24374352 | Genetics | 2014 Mar |
High-numerical-aperture cryogenic light microscopy for increased precision of superresolution reconstructions. | Nahmani M, Lanahan C, DeRosier D, Turrigiano GG | Proceedings of the National Academy of Sciences of the United States of America | 28348224 | Proc Natl Acad Sci U S A | 2017 Apr 11 |
Shear thickening of F-actin networks crosslinked with non-muscle myosin IIB. | Norstrom M, Gardel ML | Soft matter | 21552431 | Soft Matter | 2011 Jan 1 |
Local cortical tension by myosin II guides 3D endothelial cell branching. | Fischer RS, Gardel M, Ma X, Adelstein RS, Waterman CM | Current biology : CB | 19185493 | Curr Biol | 2009 Feb 10 |
Chapter 19: Mechanical response of cytoskeletal networks. | Gardel ML, Kasza KE, Brangwynne CP, Liu J, Weitz DA | Methods in cell biology | 19118688 | Methods Cell Biol | 2008 |
Contractile units in disordered actomyosin bundles arise from F-actin buckling. | Lenz M, Thoresen T, Gardel ML, Dinner AR | Physical review letters | 23003998 | Phys Rev Lett | 2012 Jun 8 |
Conserved F-actin dynamics and force transmission at cell adhesions. | Maruthamuthu V, Aratyn-Schaus Y, Gardel ML | Current opinion in cell biology | 20728328 | Curr Opin Cell Biol | 2010 Oct |
Stressing the limits of focal adhesion mechanosensitivity. | Oakes PW, Gardel ML | Current opinion in cell biology | 24998185 | Curr Opin Cell Biol | 2014 Oct |
Regulation of cell motile behavior by crosstalk between cadherin- and integrin-mediated adhesions. | Borghi N, Lowndes M, Maruthamuthu V, Gardel ML, Nelson WJ | Proceedings of the National Academy of Sciences of the United States of America | 20566866 | Proc Natl Acad Sci U S A | 2010 Jul 27 |
Reconstitution of contractile actomyosin bundles. | Thoresen T, Lenz M, Gardel ML | Biophysical journal | 21641315 | Biophys J | 2011 Jun 8 |
A zyxin-mediated mechanism for actin stress fiber maintenance and repair. | Smith MA, Blankman E, Gardel ML, Luettjohann L, Waterman CM, Beckerle MC | Developmental cell | 20833360 | Dev Cell | 2010 Sep 14 |
High resolution traction force microscopy based on experimental and computational advances. | Sabass B, Gardel ML, Waterman CM, Schwarz US | Biophysical journal | 17827246 | Biophys J | 2008 Jan 1 |
Observation and characterization of the vestige of the jamming transition in a thermal three-dimensional system. | Caswell TA, Zhang Z, Gardel ML, Nagel SR | Physical review. E, Statistical, nonlinear, and soft matter physics | 23410327 | Phys Rev E Stat Nonlin Soft Matter Phys | 2013 Jan |
Endothelial barrier disruption and recovery is controlled by substrate stiffness. | Birukova AA, Tian X, Cokic I, Beckham Y, Gardel ML, Birukov KG | Microvascular research | 23296034 | Microvasc Res | 2013 May |
Mechanical integration of actin and adhesion dynamics in cell migration. | Gardel ML, Schneider IC, Aratyn-Schaus Y, Waterman CM | Annual review of cell and developmental biology | 19575647 | Annu Rev Cell Dev Biol | 2010 |
Dynamic and structural signatures of lamellar actomyosin force generation. | Aratyn-Schaus Y, Oakes PW, Gardel ML | Molecular biology of the cell | 21307339 | Mol Biol Cell | 2011 Apr 15 |
Identification and characterization of a small molecule inhibitor of formin-mediated actin assembly. | Rizvi SA, Neidt EM, Cui J, Feiger Z, Skau CT, Gardel ML, Kozmin SA, Kovar DR | Chemistry & biology | 19942139 | Chem Biol | 2009 Nov 25 |
Mechanics of the F-actin cytoskeleton. | Stricker J, Falzone T, Gardel ML | Journal of biomechanics | 19913792 | J Biomech | 2010 Jan 5 |
Preparation of complaint matrices for quantifying cellular contraction. | Aratyn-Schaus Y, Oakes PW, Stricker J, Winter SP, Gardel ML | Journal of visualized experiments : JoVE | 21178972 | J Vis Exp | 2010 Dec 14 |
Biophysics. Clutch dynamics. | Aratyn-Schaus Y, Gardel ML | Science (New York, N.Y.) | 19074337 | Science | 2008 Dec 12 |
Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed. | Gardel ML, Sabass B, Ji L, Danuser G, Schwarz US, Waterman CM | The Journal of cell biology | 19075110 | J Cell Biol | 2008 Dec 15 |
Reconstitution of contractile actomyosin arrays. | Murrell M, Thoresen T, Gardel M | Methods in enzymology | 24630112 | Methods Enzymol | 2014 |
Optimization of traction force microscopy for micron-sized focal adhesions. | Stricker J, Sabass B, Schwarz US, Gardel ML | Journal of physics. Condensed matter : an Institute of Physics journal | 20523913 | J Phys Condens Matter | 2010 May 19 |
Transient frictional slip between integrin and the ECM in focal adhesions under myosin II tension. | Aratyn-Schaus Y, Gardel ML | Current biology : CB | 20541412 | Curr Biol | 2010 Jul 13 |
Cell-ECM traction force modulates endogenous tension at cell-cell contacts. | Maruthamuthu V, Sabass B, Schwarz US, Gardel ML | Proceedings of the National Academy of Sciences of the United States of America | 21383129 | Proc Natl Acad Sci U S A | 2011 Mar 22 |
Cell-substrate interactions. | Gardel M, Schwarz U | Journal of physics. Condensed matter : an Institute of Physics journal | 21386358 | J Phys Condens Matter | 2010 May 19 |
Requirements for contractility in disordered cytoskeletal bundles. | Lenz M, Gardel ML, Dinner AR | New journal of physics | 23155355 | New J Phys | 2012 Mar 1 |
Materials science: Synthetic polymers with biological rigidity. | Gardel ML | Nature | 23354043 | Nature | 2013 Jan 31 |
The clinically available NMDA receptor antagonist, memantine, exhibits relative safety in the developing rat brain. | Manning SM, Boll G, Fitzgerald E, Selip DB, Volpe JJ, Jensen FE | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience | 21624454 | Int J Dev Neurosci | 2011 Nov |
Does acquired epileptogenesis in the immature brain require neuronal death. | Baram TZ, Jensen FE, Brooks-Kayal A | Epilepsy currents | 21461261 | Epilepsy Curr | 2011 Jan |
Altered development of glutamatergic synapses in layer V pyramidal neurons in NR3A knockout mice. | Zhou C, Jensen FE, Sucher NJ | Molecular and cellular neurosciences | 19782137 | Mol Cell Neurosci | 2009 Dec |
Neonatal seizures: an update on mechanisms and management. | Jensen FE | Clinics in perinatology | 19944840 | Clin Perinatol | 2009 Dec |
A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival. | Meikle L, Talos DM, Onda H, Pollizzi K, Rotenberg A, Sahin M, Jensen FE, Kwiatkowski DJ | The Journal of neuroscience : the official journal of the Society for Neuroscience | 17522300 | J Neurosci | 2007 May 23 |
Early-life seizures alter synaptic calcium-permeable AMPA receptor function and plasticity. | Lippman-Bell JJ, Zhou C, Sun H, Feske JS, Jensen FE | Molecular and cellular neurosciences | 27521497 | Mol Cell Neurosci | 2016 Oct |
Strain-specific differences in perinatal rodent oligodendrocyte lineage progression and its correlation with human. | Dean JM, Moravec MD, Grafe M, Abend N, Ren J, Gong X, Volpe JJ, Jensen FE, Hohimer AR, Back SA | Developmental neuroscience | 21865655 | Dev Neurosci | 2011 |
Developmental expression of N-methyl-D-aspartate (NMDA) receptor subunits in human white and gray matter: potential mechanism of increased vulnerability in the immature brain. | Jantzie LL, Talos DM, Jackson MC, Park HK, Graham DA, Lechpammer M, Folkerth RD, Volpe JJ, Jensen FE | Cerebral cortex (New York, N.Y. : 1991) | 24046081 | Cereb Cortex | 2015 Feb |
Bumetanide enhances phenobarbital efficacy in a rat model of hypoxic neonatal seizures. | Cleary RT, Sun H, Huynh T, Manning SM, Li Y, Rotenberg A, Talos DM, Kahle KT, Jackson M, Rakhade SN, Berry G, Jensen FE | PloS one | 23536761 | PLoS One | 2013 |
AMPA receptor antagonist NBQX attenuates later-life epileptic seizures and autistic-like social deficits following neonatal seizures. | Lippman-Bell JJ, Rakhade SN, Klein PM, Obeid M, Jackson MC, Joseph A, Jensen FE | Epilepsia | 24117347 | Epilepsia | 2013 Nov |
Lestaurtinib (CEP-701) attenuates "second hit" kainic acid-induced seizures following early life hypoxic seizures. | Obeid M, Rosenberg EC, Klein PM, Jensen FE | Epilepsy research | 24582454 | Epilepsy Res | 2014 May |
Blinders, phenotype, and fashionable genetic analysis: a critical examination of the current state of epilepsy genetic studies. | Greenberg DA, Subaran R | Epilepsia | 21219301 | Epilepsia | 2011 Jan |
Association of the small GTPase Rheb with the NMDA receptor subunit NR3A. | Sucher NJ, Yu E, Chan SF, Miri M, Lee BJ, Xiao B, Worley PF, Jensen FE | Neuro-Signals | 21135540 | Neurosignals | 2010 |
Contribution of axonal orientation to pathway-dependent modulation of excitatory transmission by direct current stimulation in isolated rat hippocampus. | Kabakov AY, Muller PA, Pascual-Leone A, Jensen FE, Rotenberg A | Journal of neurophysiology | 22219028 | J Neurophysiol | 2012 Apr |
Mammalian target of rapamycin complex 1 activation negatively regulates Polo-like kinase 2-mediated homeostatic compensation following neonatal seizures. | Sun H, Kosaras B, Klein PM, Jensen FE | Proceedings of the National Academy of Sciences of the United States of America | 23479645 | Proc Natl Acad Sci U S A | 2013 Mar 26 |
The interaction between early life epilepsy and autistic-like behavioral consequences: a role for the mammalian target of rapamycin (mTOR) pathway. | Talos DM, Sun H, Zhou X, Fitzgerald EC, Jackson MC, Klein PM, Lan VJ, Joseph A, Jensen FE | PloS one | 22567115 | PLoS One | 2012 |
Chloride cotransporter NKCC1 inhibitor bumetanide protects against white matter injury in a rodent model of periventricular leukomalacia. | Jantzie LL, Hu MY, Park HK, Jackson MC, Yu J, Maxwell JR, Jensen FE | Pediatric research | 25585037 | Pediatr Res | 2015 Apr |
The tower of Babel: survey on concepts and terminology in electrical status epilepticus in sleep and continuous spikes and waves during sleep in North America. | Fernández IS, Chapman KE, Peters JM, Kothare SV, Nordli DR Jr, Jensen FE, Berg AT, Loddenkemper T | Epilepsia | 23163318 | Epilepsia | 2013 Apr |
Neonatal seizures alter NMDA glutamate receptor GluN2A and 3A subunit expression and function in hippocampal CA1 neurons. | Zhou C, Sun H, Klein PM, Jensen FE | Frontiers in cellular neuroscience | 26441533 | Front Cell Neurosci | 2015 |
Altered hippocampal dendritic spine maturation after hypoxia-induced seizures in neonatal rats. | Lippman-Bell JJ, Handy M, Nieder CG, Getzfread M, Jensen FE | Molecular and cellular neurosciences | 34015497 | Mol Cell Neurosci | 2021 Jun |
Finding a better drug for epilepsy: antiepileptogenesis targets. | Kobow K, Auvin S, Jensen F, Löscher W, Mody I, Potschka H, Prince D, Sierra A, Simonato M, Pitkänen A, Nehlig A, Rho JM | Epilepsia | 23061663 | Epilepsia | 2012 Nov |
Glutamate receptor 1 phosphorylation at serine 831 and 845 modulates seizure susceptibility and hippocampal hyperexcitability after early life seizures. | Rakhade SN, Fitzgerald EF, Klein PM, Zhou C, Sun H, Huganir RL, Jensen FE | The Journal of neuroscience : the official journal of the Society for Neuroscience | 23223299 | J Neurosci | 2012 Dec 5 |
Developmental factors in the pathogenesis of neonatal seizures. | Jensen FE | Journal of pediatric neurology : JPN | 20191097 | J Pediatr Neurol | 2009 Jan 1 |
The developing oligodendrocyte: key cellular target in brain injury in the premature infant. | Volpe JJ, Kinney HC, Jensen FE, Rosenberg PA | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience | 21382469 | Int J Dev Neurosci | 2011 Jun |
Benign rolandic epileptiform discharges are associated with mood and behavior problems. | Sarco DP, Boyer K, Lundy-Krigbaum SM, Takeoka M, Jensen F, Gregas M, Waber DP | Epilepsy & behavior : E&B | 21862414 | Epilepsy Behav | 2011 Oct |
Perfusion Imaging of Focal Cortical Dysplasia Using Arterial Spin Labeling: Correlation With Histopathological Vascular Density. | Wintermark P, Lechpammer M, Warfield SK, Kosaras B, Takeoka M, Poduri A, Madsen JR, Bergin AM, Whalen S, Jensen FE | Journal of child neurology | 23696629 | J Child Neurol | 2013 Nov |
Issues related to development of antiepileptogenic therapies. | Pitkänen A, Nehlig A, Brooks-Kayal AR, Dudek FE, Friedman D, Galanopoulou AS, Jensen FE, Kaminski RM, Kapur J, Klitgaard H, Löscher W, Mody I, Schmidt D | Epilepsia | 23909852 | Epilepsia | 2013 Aug |
Hypoxia-induced neonatal seizures diminish silent synapses and long-term potentiation in hippocampal CA1 neurons. | Zhou C, Lippman JJ, Sun H, Jensen FE | The Journal of neuroscience : the official journal of the Society for Neuroscience | 22171027 | J Neurosci | 2011 Dec 14 |
Epileptogenesis in the immature brain: emerging mechanisms. | Rakhade SN, Jensen FE | Nature reviews. Neurology | 19578345 | Nat Rev Neurol | 2009 Jul |
An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. | Brownstein CA, Beggs AH, Homer N, Merriman B, Yu TW, Flannery KC, DeChene ET, Towne MC, Savage SK, Price EN, Holm IA, Luquette LJ, Lyon E, Majzoub J, Neupert P, McCallie D Jr, Szolovits P, Willard HF, Mendelsohn NJ, Temme R, Finkel RS, Yum SW, Medne L, Sunyaev SR, Adzhubey I, Cassa CA, de Bakker PI, Duzkale H, Dworzyński P, Fairbrother W, Francioli L, Funke BH, Giovanni MA, Handsaker RE, Lage K, Lebo MS, Lek M, Leshchiner I, MacArthur DG, McLaughlin HM, Murray MF, Pers TH, Polak PP, Raychaudhuri S, Rehm HL, Soemedi R, Stitziel NO, Vestecka S, Supper J, Gugenmus C, Klocke B, Hahn A, Schubach M, Menzel M, Biskup S, Freisinger P, Deng M, Braun M, Perner S, Smith RJ, Andorf JL, Huang J, Ryckman K, Sheffield VC, Stone EM, Bair T, Black-Ziegelbein EA, Braun TA, Darbro B, DeLuca AP, Kolbe DL, Scheetz TE, Shearer AE, Sompallae R, Wang K, Bassuk AG, Edens E, Mathews K, Moore SA, Shchelochkov OA, Trapane P, Bossler A, Campbell CA, Heusel JW, Kwitek A, Maga T, Panzer K, Wassink T, Van Daele D, Azaiez H, Booth K, Meyer N, Segal MM, Williams MS, Tromp G, White P, Corsmeier D, Fitzgerald-Butt S, Herman G, Lamb-Thrush D, McBride KL, Newsom D, Pierson CR, Rakowsky AT, Maver A, Lovrečić L, Palandačić A, Peterlin B, Torkamani A, Wedell A, Huss M, Alexeyenko A, Lindvall JM, Magnusson M, Nilsson D, Stranneheim H, Taylan F, Gilissen C, Hoischen A, van Bon B, Yntema H, Nelen M, Zhang W, Sager J, Zhang L, Blair K, Kural D, Cariaso M, Lennon GG, Javed A, Agrawal S, Ng PC, Sandhu KS, Krishna S, Veeramachaneni V, Isakov O, Halperin E, Friedman E, Shomron N, Glusman G, Roach JC, Caballero J, Cox HC, Mauldin D, Ament SA, Rowen L, Richards DR, San Lucas FA, Gonzalez-Garay ML, Caskey CT, Bai Y, Huang Y, Fang F, Zhang Y, Wang Z, Barrera J, Garcia-Lobo JM, González-Lamuño D, Llorca J, Rodriguez MC, Varela I, Reese MG, De La Vega FM, Kiruluta E, Cargill M, Hart RK, Sorenson JM, Lyon GJ, Stevenson DA, Bray BE, Moore BM, Eilbeck K, Yandell M, Zhao H, Hou L, Chen X, Yan X, Chen M, Li C, Yang C, Gunel M, Li P, Kong Y, Alexander AC, Albertyn ZI, Boycott KM, Bulman DE, Gordon PM, Innes AM, Knoppers BM, Majewski J, Marshall CR, Parboosingh JS, Sawyer SL, Samuels ME, Schwartzentruber J, Kohane IS, Margulies DM | Genome biology | 24667040 | Genome Biol | 2014 Mar 25 |
Subunit composition of glutamate and gamma-aminobutyric acid receptors in status epilepticus. | Loddenkemper T, Talos DM, Cleary RT, Joseph A, Sánchez Fernández I, Alexopoulos A, Kotagal P, Najm I, Jensen FE | Epilepsy research | 24613745 | Epilepsy Res | 2014 May |
Cannabidiol attenuates seizure susceptibility and behavioural deficits in adult CDKL5(R59X) knock-in mice. | Li X, Yennawar M, Wiest A, O'Brien WT, Babrowicz B, White RS, Talos DM, Jensen FE | The European journal of neuroscience | 38654472 | Eur J Neurosci | 2024 Jun |
Regional differences in susceptibility to hypoxic-ischemic injury in the preterm brain: exploring the spectrum from white matter loss to selective grey matter injury in a rat model. | Selip DB, Jantzie LL, Chang M, Jackson MC, Fitzgerald EC, Boll G, Murphy A, Jensen FE | Neurology research international | 22530125 | Neurol Res Int | 2012 |
Epilepsy as a spectrum disorder: Implications from novel clinical and basic neuroscience. | Jensen FE | Epilepsia | 21214533 | Epilepsia | 2011 Jan |
Development of later life spontaneous seizures in a rodent model of hypoxia-induced neonatal seizures. | Rakhade SN, Klein PM, Huynh T, Hilario-Gomez C, Kosaras B, Rotenberg A, Jensen FE | Epilepsia | 21366558 | Epilepsia | 2011 Apr |
Altered inhibition in tuberous sclerosis and type IIb cortical dysplasia. | Talos DM, Sun H, Kosaras B, Joseph A, Folkerth RD, Poduri A, Madsen JR, Black PM, Jensen FE | Annals of neurology | 22447678 | Ann Neurol | 2012 Apr |
Antiepileptic effects of levetiracetam in a rodent neonatal seizure model. | Talos DM, Chang M, Kosaras B, Fitzgerald E, Murphy A, Folkerth RD, Jensen FE | Pediatric research | 23138400 | Pediatr Res | 2013 Jan |
Issues related to symptomatic and disease-modifying treatments affecting cognitive and neuropsychiatric comorbidities of epilepsy. | Brooks-Kayal AR, Bath KG, Berg AT, Galanopoulou AS, Holmes GL, Jensen FE, Kanner AM, O'Brien TJ, Whittemore VH, Winawer MR, Patel M, Scharfman HE | Epilepsia | 23909853 | Epilepsia | 2013 Aug |
Epilepsy biomarkers. | Engel J Jr, Pitkänen A, Loeb JA, Dudek FE, Bertram EH 3rd, Cole AJ, Moshé SL, Wiebe S, Jensen FE, Mody I, Nehlig A, Vezzani A | Epilepsia | 23909854 | Epilepsia | 2013 Aug |
Developmental regulation of group I metabotropic glutamate receptors in the premature brain and their protective role in a rodent model of periventricular leukomalacia. | Jantzie LL, Talos DM, Selip DB, An L, Jackson MC, Folkerth RD, Deng W, Jensen FE | Neuron glia biology | 22169210 | Neuron Glia Biol | 2010 Nov |
Early alterations of AMPA receptors mediate synaptic potentiation induced by neonatal seizures. | Rakhade SN, Zhou C, Aujla PK, Fishman R, Sucher NJ, Jensen FE | The Journal of neuroscience : the official journal of the Society for Neuroscience | 18685023 | J Neurosci | 2008 Aug 6 |
Gene expression profiling of a hypoxic seizure model of epilepsy suggests a role for mTOR and Wnt signaling in epileptogenesis. | Theilhaber J, Rakhade SN, Sudhalter J, Kothari N, Klein P, Pollard J, Jensen FE | PloS one | 24086344 | PLoS One | 2013 |
AMPA Receptor Dysregulation and Therapeutic Interventions in a Mouse Model of CDKL5 Deficiency Disorder. | Yennawar M, White RS, Jensen FE | The Journal of neuroscience : the official journal of the Society for Neuroscience | 30952813 | J Neurosci | 2019 Jun 12 |
Regulation of seizure-induced MeCP2 Ser421 phosphorylation in the developing brain. | Rosenberg EC, Lippman-Bell JJ, Handy M, Soldan SS, Rakhade S, Hilario-Gomez C, Folweiler K, Jacobs L, Jensen FE | Neurobiology of disease | 29738885 | Neurobiol Dis | 2018 Aug |
Models of hypoxia and ischemia-induced seizures. | Sun H, Juul HM, Jensen FE | Journal of neuroscience methods | 26434705 | J Neurosci Methods | 2016 Feb 15 |
Dysregulation of FMRP/mTOR Signaling Cascade in Hypoxic-Ischemic Injury of Premature Human Brain. | Lechpammer M, Wintermark P, Merry KM, Jackson MC, Jantzie LL, Jensen FE | Journal of child neurology | 26239490 | J Child Neurol | 2016 Mar |
Reading chimpanzee faces: evidence for the role of verbal labels in categorical perception of emotion. | Fugate JM, Gouzoules H, Barrett LF | Emotion (Washington, D.C.) | 20677871 | Emotion | 2010 Aug |
A reliable protocol for the manual segmentation of the human amygdala and its subregions using ultra-high resolution MRI. | Entis JJ, Doerga P, Barrett LF, Dickerson BC | NeuroImage | 22245260 | Neuroimage | 2012 Apr 2 |
Emotion Generation and Emotion Regulation: One or Two Depends on Your Point of View. | Gross JJ, Barrett LF | Emotion review : journal of the International Society for Research on Emotion | 21479078 | Emot Rev | 2011 Jan |
Reconstructing the Past: A Century of Ideas About Emotion in Psychology. | Gendron M, Barrett LF | Emotion review : journal of the International Society for Research on Emotion | 20221412 | Emot Rev | 2009 Oct 1 |
The Future of Psychology: Connecting Mind to Brain. | Barrett LF | Perspectives on psychological science : a journal of the Association for Psychological Science | 19844601 | Perspect Psychol Sci | 2009 Jul |
Novelty as a dimension in the affective brain. | Weierich MR, Wright CI, Negreira A, Dickerson BC, Barrett LF | NeuroImage | 19796697 | Neuroimage | 2010 Feb 1 |
Emotions are real. | Barrett LF | Emotion (Washington, D.C.) | 22642358 | Emotion | 2012 Jun |
Intrinsic amygdala-cortical functional connectivity predicts social network size in humans. | Bickart KC, Hollenbeck MC, Barrett LF, Dickerson BC | The Journal of neuroscience : the official journal of the Society for Neuroscience | 23077058 | J Neurosci | 2012 Oct 17 |
A functional architecture of the human brain: emerging insights from the science of emotion. | Lindquist KA, Barrett LF | Trends in cognitive sciences | 23036719 | Trends Cogn Sci | 2012 Nov |
Authors’ response: what are emotions and how are they created in the brain? | Lindquist KA, Wager TD, Bliss-Moreau E, Kober H, Barret LF | The Behavioral and brain sciences | 22783560 | Behav Brain Sci | 2012 Jun |
Affective value and associative processing share a cortical substrate. | Shenhav A, Barrett LF, Bar M | Cognitive, affective & behavioral neuroscience | 23090717 | Cogn Affect Behav Neurosci | 2013 Mar |
Emotional granularity and borderline personality disorder. | Suvak MK, Litz BT, Sloan DM, Zanarini MC, Barrett LF, Hofmann SG | Journal of abnormal psychology | 21171723 | J Abnorm Psychol | 2011 May |
Bridging Token Identity Theory and Supervenience Theory Through Psychological Construction. | Barrett LF | Psychological inquiry | 21785534 | Psychol Inq | 2011 Jan 1 |
Emotion perception, but not affect perception, is impaired with semantic memory loss. | Lindquist KA, Gendron M, Barrett LF, Dickerson BC | Emotion (Washington, D.C.) | 24512242 | Emotion | 2014 Apr |
The Brain Basis of Positive and Negative Affect: Evidence from a Meta-Analysis of the Human Neuroimaging Literature. | Lindquist KA, Satpute AB, Wager TD, Weber J, Barrett LF | Cerebral cortex (New York, N.Y. : 1991) | 25631056 | Cereb Cortex | 2016 May |
Involvement of Sensory Regions in Affective Experience: A Meta-Analysis. | Satpute AB, Kang J, Bickart KC, Yardley H, Wager TD, Barrett LF | Frontiers in psychology | 26696928 | Front Psychol | 2015 |
A Bayesian model of category-specific emotional brain responses. | Wager TD, Kang J, Johnson TD, Nichols TE, Satpute AB, Barrett LF | PLoS computational biology | 25853490 | PLoS Comput Biol | 2015 Apr |
The power of predictions: An emerging paradigm for psychological research. | Hutchinson JB, Barrett LF | Current directions in psychological science | 31749520 | Curr Dir Psychol Sci | 2019 Jun |
Valence focus and self-esteem lability: reacting to hedonic cues in the social environment. | Pietromonaco PR, Barrett LF | Emotion (Washington, D.C.) | 19485618 | Emotion | 2009 Jun |
Affective learning enhances activity and functional connectivity in early visual cortex. | Damaraju E, Huang YM, Barrett LF, Pessoa L | Neuropsychologia | 19410587 | Neuropsychologia | 2009 Oct |
Neural correlates of novelty and face-age effects in young and elderly adults. | Wright CI, Negreira A, Gold AL, Britton JC, Williams D, Barrett LF | NeuroImage | 18586522 | Neuroimage | 2008 Aug 15 |
Conceptualizing and experiencing compassion. | Condon P, Feldman Barrett L | Emotion (Washington, D.C.) | 23914766 | Emotion | 2013 Oct |
Sex differences in the neural correlates of affective experience. | Moriguchi Y, Touroutoglou A, Dickerson BC, Barrett LF | Social cognitive and affective neuroscience | 23596188 | Soc Cogn Affect Neurosci | 2014 May |
Decision making from economic and signal detection perspectives: development of an integrated framework. | Lynn SK, Wormwood JB, Barrett LF, Quigley KS | Frontiers in psychology | 26217275 | Front Psychol | 2015 |
Situating emotional experience. | Wilson-Mendenhall CD, Barrett LF, Barsalou LW | Frontiers in human neuroscience | 24324420 | Front Hum Neurosci | 2013 |
Heightened sensitivity to emotional expressions in generalised anxiety disorder, compared to social anxiety disorder, and controls. | Bui E, Anderson E, Goetter EM, Campbell AA, Fischer LE, Barrett LF, Simon NM | Cognition & emotion | 26395075 | Cogn Emot | 2017 Jan |
The neural representation of typical and atypical experiences of negative images: comparing fear, disgust and morbid fascination. | Oosterwijk S, Lindquist KA, Adebayo M, Barrett LF | Social cognitive and affective neuroscience | 26180088 | Soc Cogn Affect Neurosci | 2016 Jan |
Brain network connectivity-behavioral relationships exhibit trait-like properties: Evidence from hippocampal connectivity and memory. | Touroutoglou A, Andreano JM, Barrett LF, Dickerson BC | Hippocampus | 26105075 | Hippocampus | 2015 Dec |
Older and wiser? An affective science perspective on age-related challenges in financial decision making. | Weierich MR, Kensinger EA, Munnell AH, Sass SA, Dickerson BC, Wright CI, Barrett LF | Social cognitive and affective neuroscience | 20587596 | Soc Cogn Affect Neurosci | 2011 Apr |
Out of sight but not out of mind: unseen affective faces influence evaluations and social impressions. | Anderson E, Siegel E, White D, Barrett LF | Emotion (Washington, D.C.) | 22506501 | Emotion | 2012 Dec |
Trends in ambulatory self-report: the role of momentary experience in psychosomatic medicine. | Conner TS, Barrett LF | Psychosomatic medicine | 22582330 | Psychosom Med | 2012 May |
The visual impact of gossip. | Anderson E, Siegel EH, Bliss-Moreau E, Barrett LF | Science (New York, N.Y.) | 21596956 | Science | 2011 Jun 17 |
How does this make you feel? A comparison of four affect induction procedures. | Zhang X, Yu HW, Barrett LF | Frontiers in psychology | 25071659 | Front Psychol | 2014 |
Is there consistency and specificity of autonomic changes during emotional episodes? Guidance from the Conceptual Act Theory and psychophysiology. | Quigley KS, Barrett LF | Biological psychology | 24388802 | Biol Psychol | 2014 Apr |
Variety in emotional life: within-category typicality of emotional experiences is associated with neural activity in large-scale brain networks. | Wilson-Mendenhall CD, Barrett LF, Barsalou LW | Social cognitive and affective neuroscience | 24563528 | Soc Cogn Affect Neurosci | 2015 Jan |
Unseen Affective Faces Influence Person Perception Judgments in Schizophrenia. | Kring AM, Siegel EH, Barrett LF | Clinical psychological science : a journal of the Association for Psychological Science | 25664225 | Clin Psychol Sci | 2014 Jul |
Gender differences in oxytocin-associated disruption of decision bias during emotion perception. | Lynn SK, Hoge EA, Fischer LE, Barrett LF, Simon NM | Psychiatry research | 24814142 | Psychiatry Res | 2014 Sep 30 |
Functional connectivity dynamics during film viewing reveal common networks for different emotional experiences. | Raz G, Touroutoglou A, Wilson-Mendenhall C, Gilam G, Lin T, Gonen T, Jacob Y, Atzil S, Admon R, Bleich-Cohen M, Maron-Katz A, Hendler T, Barrett LF | Cognitive, affective & behavioral neuroscience | 27142636 | Cogn Affect Behav Neurosci | 2016 Aug |
Emotion words: Adding face value. | Fugate JMB, Gendron M, Nakashima SF, Barrett LF | Emotion (Washington, D.C.) | 28604040 | Emotion | 2018 Aug |
Risk Factors, Neuroanatomical Correlates, and Outcome of Neuropsychiatric Symptoms in Alzheimer's Disease. | Poulin SP, Bergeron D, Dickerson BC, Alzheimer’s Disease Neuroimaging Initiative | Journal of Alzheimer's disease : JAD | 28869463 | J Alzheimers Dis | 2017 |
Internal valence modulates the speed of object recognition. | Panichello MF, Kveraga K, Chaumon M, Bar M, Barrett LF | Scientific reports | 28336933 | Sci Rep | 2017 Mar 23 |
Emotion fingerprints or emotion populations? A meta-analytic investigation of autonomic features of emotion categories. | Siegel EH, Sands MK, Van den Noortgate W, Condon P, Chang Y, Dy J, Quigley KS, Barrett LF | Psychological bulletin | 29389177 | Psychol Bull | 2018 Apr |
Large-scale brain networks in affective and social neuroscience: towards an integrative functional architecture of the brain. | Barrett LF, Satpute AB | Current opinion in neurobiology | 23352202 | Curr Opin Neurobiol | 2013 Jun |
The hundred-year emotion war: are emotions natural kinds or psychological constructions? Comment on Lench, Flores, and Bench (2011). | Lindquist KA, Siegel EH, Quigley KS, Barrett LF | Psychological bulletin | 23294094 | Psychol Bull | 2013 Jan |
The relation between valence and arousal in subjective experience. | Kuppens P, Tuerlinckx F, Russell JA, Barrett LF | Psychological bulletin | 23231533 | Psychol Bull | 2013 Jul |
She's emotional. He's having a bad day: attributional explanations for emotion stereotypes. | Barrett LF, Bliss-Moreau E | Emotion (Washington, D.C.) | 19803587 | Emotion | 2009 Oct |
Constructing emotion: the experience of fear as a conceptual act. | Lindquist KA, Barrett LF | Psychological science | 18947355 | Psychol Sci | 2008 Sep |
Affect as a Psychological Primitive. | Barrett LF, Bliss-Moreau E | Advances in experimental social psychology | 20552040 | Adv Exp Soc Psychol | 2009 |
I Like the Sound of Your Voice: Affective Learning about Vocal Signals. | Bliss-Moreau E, Barrett LF, Owren MJ | Journal of experimental social psychology | 20495619 | J Exp Soc Psychol | 2010 May 1 |
Amygdala volume and social network size in humans. | Bickart KC, Wright CI, Dautoff RJ, Dickerson BC, Barrett LF | Nature neuroscience | 21186358 | Nat Neurosci | 2011 Feb |
Differential hemodynamic response in affective circuitry with aging: an FMRI study of novelty, valence, and arousal. | Moriguchi Y, Negreira A, Weierich M, Dautoff R, Dickerson BC, Wright CI, Barrett LF | Journal of cognitive neuroscience | 20521849 | J Cogn Neurosci | 2011 May |
The brain basis of emotion: a meta-analytic review. | Lindquist KA, Wager TD, Kober H, Bliss-Moreau E, Barrett LF | The Behavioral and brain sciences | 22617651 | Behav Brain Sci | 2012 Jun |
Identification of discrete functional subregions of the human periaqueductal gray. | Satpute AB, Wager TD, Cohen-Adad J, Bianciardi M, Choi JK, Buhle JT, Wald LL, Barrett LF | Proceedings of the National Academy of Sciences of the United States of America | 24082116 | Proc Natl Acad Sci U S A | 2013 Oct 15 |
Atrophy in distinct corticolimbic networks in frontotemporal dementia relates to social impairments measured using the Social Impairment Rating Scale. | Bickart KC, Brickhouse M, Negreira A, Sapolsky D, Barrett LF, Dickerson BC | Journal of neurology, neurosurgery, and psychiatry | 24133285 | J Neurol Neurosurg Psychiatry | 2014 Apr |
Visual predictions in the orbitofrontal cortex rely on associative content. | Chaumon M, Kveraga K, Barrett LF, Bar M | Cerebral cortex (New York, N.Y. : 1991) | 23771980 | Cereb Cortex | 2014 Nov |
Individual differences in learning the affective value of others under minimal conditions. | Bliss-Moreau E, Barrett LF, Wright CI | Emotion (Washington, D.C.) | 18729580 | Emotion | 2008 Aug |
Amygdala and fusiform gyrus temporal dynamics: responses to negative facial expressions. | Britton JC, Shin LM, Barrett LF, Rauch SL, Wright CI | BMC neuroscience | 18474111 | BMC Neurosci | 2008 May 12 |
What You Feel Influences What You See: The Role of Affective Feelings in Resolving Binocular Rivalry. | Anderson E, Siegel EH, Barrett LF | Journal of experimental social psychology | 21789027 | J Exp Soc Psychol | 2011 Jul |
Amygdala atrophy is prominent in early Alzheimer's disease and relates to symptom severity. | Poulin SP, Dautoff R, Morris JC, Barrett LF, Dickerson BC, Alzheimer's Disease Neuroimaging Initiative | Psychiatry research | 21920712 | Psychiatry Res | 2011 Oct 31 |
Variety is the spice of life: A psychological construction approach to understanding variability in emotion. | Barrett LF | Cognition & emotion | 20221411 | Cogn Emot | 2009 Nov 1 |
Establishing the situated features associated with perceived stress. | Lebois LA, Hertzog C, Slavich GM, Barrett LF, Barsalou LW | Acta psychologica | 27288834 | Acta Psychol (Amst) | 2016 Sep |
Threat perception after the Boston Marathon bombings: The effects of personal relevance and conceptual framing. | Wormwood JB, Lynn SK, Feldman Barrett L, Quigley KS | Cognition & emotion | 25707419 | Cogn Emot | 2016 |
Amygdala task-evoked activity and task-free connectivity independently contribute to feelings of arousal. | Touroutoglou A, Bickart KC, Barrett LF, Dickerson BC | Human brain mapping | 24862171 | Hum Brain Mapp | 2014 Oct |
Emotion words, emotion concepts, and emotional development in children: A constructionist hypothesis. | Hoemann K, Xu F, Barrett LF | Developmental psychology | 31464489 | Dev Psychol | 2019 Sep |
Learning situated emotions. | Lebois LAM, Wilson-Mendenhall CD, Simmons WK, Barrett LF, Barsalou LW | Neuropsychologia | 29330097 | Neuropsychologia | 2020 Aug |
Primary Interoceptive Cortex Activity during Simulated Experiences of the Body. | Wilson-Mendenhall CD, Henriques A, Barsalou LW, Barrett LF | Journal of cognitive neuroscience | 30277431 | J Cogn Neurosci | 2019 Feb |
A shift in perspective: Decentering through mindful attention to imagined stressful events. | Lebois LA, Papies EK, Gopinath K, Cabanban R, Quigley KS, Krishnamurthy V, Barrett LF, Barsalou LW | Neuropsychologia | 26111487 | Neuropsychologia | 2015 Aug |
Methodological recommendations for a heartbeat detection-based measure of interoceptive sensitivity. | Kleckner IR, Wormwood JB, Simmons WK, Barrett LF, Quigley KS | Psychophysiology | 26265009 | Psychophysiology | 2015 Nov |
Does language do more than communicate emotion? | Lindquist KA, Satpute AB, Gendron M | Current directions in psychological science | 25983400 | Curr Dir Psychol Sci | 2015 Apr 1 |
Semantic Clustering during Verbal Episodic Memory Encoding and Retrieval in Older Adults: One Cognitive Mechanism of Superaging. | Shaffer C, Andreano JM, Touroutoglou A, Barrett LF, Dickerson BC, Wong B | Brain sciences | 38391745 | Brain Sci | 2024 Feb 8 |
See it with feeling: affective predictions during object perception. | Barrett LF, Bar M | Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 19528014 | Philos Trans R Soc Lond B Biol Sci | 2009 May 12 |
Considering PTSD from the perspective of brain processes: a psychological construction approach. | Suvak MK, Barrett LF | Journal of traumatic stress | 21298725 | J Trauma Stress | 2011 Feb |
Emotion words shape emotion percepts. | Gendron M, Lindquist KA, Barsalou L, Barrett LF | Emotion (Washington, D.C.) | 22309717 | Emotion | 2012 Apr |
States of mind: emotions, body feelings, and thoughts share distributed neural networks. | Oosterwijk S, Lindquist KA, Anderson E, Dautoff R, Moriguchi Y, Barrett LF | NeuroImage | 22677148 | Neuroimage | 2012 Sep |
Neural evidence that human emotions share core affective properties. | Wilson-Mendenhall CD, Barrett LF, Barsalou LW | Psychological science | 23603916 | Psychol Sci | 2013 Jun |
Dissociable large-scale networks anchored in the right anterior insula subserve affective experience and attention. | Touroutoglou A, Hollenbeck M, Dickerson BC, Feldman Barrett L | NeuroImage | 22361166 | Neuroimage | 2012 May 1 |
Grounding emotion in situated conceptualization. | Wilson-Mendenhall CD, Barrett LF, Simmons WK, Barsalou LW | Neuropsychologia | 21192959 | Neuropsychologia | 2011 Apr |
Affective state influences perception by affecting decision parameters underlying bias and sensitivity. | Lynn SK, Zhang X, Barrett LF | Emotion (Washington, D.C.) | 22251054 | Emotion | 2012 Aug |
The role of affective experience in work motivation: Test of a conceptual model. | Seo MG, Bartunek JM, Barrett LF | Journal of organizational behavior | 21785527 | J Organ Behav | 2010 Oct |
Experience Sampling Methods: A Modern Idiographic Approach to Personality Research. | Conner TS, Tennen H, Fleeson W, Barrett LF | Social and personality psychology compass | 19898679 | Soc Personal Psychol Compass | 2009 May 1 |
Functional grouping and cortical-subcortical interactions in emotion: a meta-analysis of neuroimaging studies. | Kober H, Barrett LF, Joseph J, Bliss-Moreau E, Lindquist K, Wager TD | NeuroImage | 18579414 | Neuroimage | 2008 Aug 15 |
Understanding the Mind by Measuring the Brain: Lessons From Measuring Behavior (Commentary on Vul et al., 2009). | Barrett LF | Perspectives on psychological science : a journal of the Association for Psychological Science | 19672318 | Perspect Psychol Sci | 2009 May |
Context is routinely encoded during emotion perception. | Barrett LF, Kensinger EA | Psychological science | 20424107 | Psychol Sci | 2010 Apr |
Perceptions of emotion from facial expressions are not culturally universal: evidence from a remote culture. | Gendron M, Roberson D, van der Vyver JM, Barrett LF | Emotion (Washington, D.C.) | 24708506 | Emotion | 2014 Apr |
Cultural variation in emotion perception is real: a response to Sauter, Eisner, Ekman, and Scott (2015). | Gendron M, Roberson D, Barrett LF | Psychological science | 25608863 | Psychol Sci | 2015 Mar |
Stronger Functional Connectivity in the Default Mode and Salience Networks Is Associated With Youthful Memory in Superaging. | Zhang J, Andreano JM, Dickerson BC, Touroutoglou A, Barrett LF | Cerebral cortex (New York, N.Y. : 1991) | 31058917 | Cereb Cortex | 2020 Jan 10 |
Conscious awareness is necessary for affective faces to influence social judgments. | Kleckner IR, Anderson EC, Betz NJ, Wormwood JB, Eskew RT Jr, Barrett LF | Journal of experimental social psychology | 31097841 | J Exp Soc Psychol | 2018 Nov |
Emotion Words' Effect on Visual Awareness and Attention of Emotional Faces. | Fugate JMB, MacDonald C, O'Hare AJ | Frontiers in psychology | 32010012 | Front Psychol | 2019 |
Words are a context for mental inference. | Betz N, Hoemann K, Barrett LF | Emotion (Washington, D.C.) | 30628815 | Emotion | 2019 Dec |
Introducing a Face Sort Paradigm to Evaluate Age Differences in Emotion Perception. | Hoemann K, Vicaria IM, Gendron M, Stanley JT | The journals of gerontology. Series B, Psychological sciences and social sciences | 32211791 | J Gerontol B Psychol Sci Soc Sci | 2021 Aug 13 |
Cultural relativity in perceiving emotion from vocalizations. | Gendron M, Roberson D, van der Vyver JM, Barrett LF | Psychological science | 24501109 | Psychol Sci | 2014 Apr |
"Utilizing" signal detection theory. | Lynn SK, Barrett LF | Psychological science | 25097061 | Psychol Sci | 2014 Sep |
Intrinsic connectivity in the human brain does not reveal networks for 'basic' emotions. | Touroutoglou A, Lindquist KA, Dickerson BC, Barrett LF | Social cognitive and affective neuroscience | 25680990 | Soc Cogn Affect Neurosci | 2015 Sep |
AFFECT AND THE FRAMING EFFECT WITHIN INDIVIDUALS OVER TIME: RISK TAKING IN A DYNAMIC INVESTMENT SIMULATION. | Seo MG, Goldfarb B, Barrett LF | Academy of Management journal. Academy of Management | 26412860 | Acad Manage J | 2010 Apr |
Working memory capacity is associated with optimal adaptation of response bias to perceptual sensitivity in emotion perception. | Lynn SK, Ibagon C, Bui E, Palitz SA, Simon NM, Barrett LF | Emotion (Washington, D.C.) | 26461251 | Emotion | 2016 Mar |
Gender moderates the effect of oxytocin on social judgments. | Hoge EA, Anderson E, Lawson EA, Bui E, Fischer LE, Khadge SD, Barrett LF, Simon NM | Human psychopharmacology | 24911580 | Hum Psychopharmacol | 2014 May |
Novel response patterns during repeated presentation of affective and neutral stimuli. | Satpute AB, Hanington L, Barrett LF | Social cognitive and affective neuroscience | 27928070 | Soc Cogn Affect Neurosci | 2016 Dec |
Emotional Granularity is Associated with Daily Experiential Diversity. | Hoemann K, Lee Y, Kuppens P, Gendron M, Boyd RL | Affective science | 37304562 | Affect Sci | 2023 Jun |
Passenger mutations as a marker of clonal cell lineages in emerging neoplasia. | Salk JJ, Horwitz MS | Seminars in cancer biology | 20951806 | Semin Cancer Biol | 2010 Oct |
Clonal expansions in ulcerative colitis identify patients with neoplasia. | Salk JJ, Salipante SJ, Risques RA, Crispin DA, Li L, Bronner MP, Brentnall TA, Rabinovitch PS, Horwitz MS, Loeb LA | Proceedings of the National Academy of Sciences of the United States of America | 19926851 | Proc Natl Acad Sci U S A | 2009 Dec 8 |
Decoding cell lineage from acquired mutations using arbitrary deep sequencing. | Carlson CA, Kas A, Kirkwood R, Hays LE, Preston BD, Salipante SJ, Horwitz MS | Nature methods | 22120468 | Nat Methods | 2011 Nov 27 |
Use of somatic mutations to quantify random contributions to mouse development. | Zhou W, Tan Y, Anderson DJ, Crist EM, Ruohola-Baker H, Salipante SJ, Horwitz MS | BMC genomics | 23327737 | BMC Genomics | 2013 Jan 18 |
Phylogenetic analysis of developmental and postnatal mouse cell lineages. | Salipante SJ, Kas A, McMonagle E, Horwitz MS | Evolution & development | 20156285 | Evol Dev | 2010 Jan-Feb |
Phylogenetic fate mapping: theoretical and experimental studies applied to the development of mouse fibroblasts. | Salipante SJ, Thompson JM, Horwitz MS | Genetics | 18245843 | Genetics | 2008 Feb |
Interaction of streptavidin-based peptide-MHC oligomers (tetramers) with cell-surface TCRs. | Stone JD, Artyomov MN, Chervin AS, Chakraborty AK, Eisen HN, Kranz DM | Journal of immunology (Baltimore, Md. : 1950) | 22102724 | J Immunol | 2011 Dec 15 |
The membrane environment can promote or suppress bistability in cell signaling networks. | Abel SM, Roose JP, Groves JT, Weiss A, Chakraborty AK | The journal of physical chemistry. B | 22332778 | J Phys Chem B | 2012 Mar 22 |
Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection. | Kosmrlj A, Read EL, Qi Y, Allen TM, Altfeld M, Deeks SG, Pereyra F, Carrington M, Walker BD, Chakraborty AK | Nature | 20445539 | Nature | 2010 May 20 |
The effect of mutations on the alloreactive T cell receptor/peptide-MHC interface structure: a molecular dynamics study. | Wolfson MY, Nam K, Chakraborty AK | The journal of physical chemistry. B | 21651302 | J Phys Chem B | 2011 Jun 30 |
Spin models inferred from patient-derived viral sequence data faithfully describe HIV fitness landscapes. | Shekhar K, Ruberman CF, Ferguson AL, Barton JP, Kardar M, Chakraborty AK | Physical review. E, Statistical, nonlinear, and soft matter physics | 24483484 | Phys Rev E Stat Nonlin Soft Matter Phys | 2013 Dec |
Empty class II major histocompatibility complex created by peptide photolysis establishes the role of DM in peptide association. | Grotenbreg GM, Nicholson MJ, Fowler KD, Wilbuer K, Octavio L, Yang M, Chakraborty AK, Ploegh HL, Wucherpfennig KW | The Journal of biological chemistry | 17525157 | J Biol Chem | 2007 Jul 20 |
A superposable silicon synapse with programmable reversal potential. | Benjamin BV, Arthur JV, Gao P, Merolla P, Boahen K | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 23366006 | Annu Int Conf IEEE Eng Med Biol Soc | 2012 |
Space coding by gamma oscillations in the barn owl optic tectum. | Sridharan D, Boahen K, Knudsen EI | Journal of neurophysiology | 21325681 | J Neurophysiol | 2011 May |
Neurotech for neuroscience: unifying concepts, organizing principles, and emerging tools. | Silver R, Boahen K, Grillner S, Kopell N, Olsen KL | The Journal of neuroscience : the official journal of the Society for Neuroscience | 17978017 | J Neurosci | 2007 Oct 31 |
Silicon-Neuron Design: A Dynamical Systems Approach. | Arthur JV, Boahen K | IEEE transactions on circuits and systems. I, Regular papers : a publication of the IEEE Circuits and Systems Society | 21617741 | IEEE Trans Circuits Syst I Regul Pap | 2011 |
Microbial invasion of the amniotic cavity in preeclampsia as assessed by cultivation and sequence-based methods. | DiGiulio DB, Gervasi M, Romero R, Mazaki-Tovi S, Vaisbuch E, Kusanovic JP, Seok KS, Gómez R, Mittal P, Gotsch F, Chaiworapongsa T, Oyarzún E, Kim CJ, Relman DA | Journal of perinatal medicine | 20482470 | J Perinat Med | 2010 Sep |
Comparisons of clustered regularly interspaced short palindromic repeats and viromes in human saliva reveal bacterial adaptations to salivary viruses. | Pride DT, Salzman J, Relman DA | Environmental microbiology | 22583485 | Environ Microbiol | 2012 Sep |
Development of the human infant intestinal microbiota. | Palmer C, Bik EM, DiGiulio DB, Relman DA, Brown PO | PLoS biology | 17594176 | PLoS Biol | 2007 Jul |
Analysis of streptococcal CRISPRs from human saliva reveals substantial sequence diversity within and between subjects over time. | Pride DT, Sun CL, Salzman J, Rao N, Loomer P, Armitage GC, Banfield JF, Relman DA | Genome research | 21149389 | Genome Res | 2011 Jan |
Genetic technologies. Synthetic "life," ethics, national security, and public discourse. | Cho MK, Relman DA | Science (New York, N.Y.) | 20595601 | Science | 2010 Jul 2 |
Characterizing the oral and distal gut microbiota of the threatened southern sea otter (Enhydra lutris nereis) to enhance conservation practice. | Dudek NK, Switzer AD, Costello EK, Murray MJ, Tomoleoni JA, Staedler MM, Tinker MT, Relman DA | Conservation science and practice | 35382031 | Conserv Sci Pract | 2022 Apr |
Microbiome assembly across multiple body sites in low-birthweight infants. | Costello EK, Carlisle EM, Bik EM, Morowitz MJ, Relman DA | mBio | 24169577 | mBio | 2013 Oct 29 |
Restoration of the gut microbial habitat as a disease therapy. | Relman DA | Nature biotechnology | 23302933 | Nat Biotechnol | 2013 Jan |
"Inconvenient truths" in the pursuit of scientific knowledge and public health. | Relman DA | The Journal of infectious diseases | 24106297 | J Infect Dis | 2014 Jan 15 |
Thinking about the microbiome as a causal factor in human health and disease: philosophical and experimental considerations. | Relman DA | Current opinion in microbiology | 32114367 | Curr Opin Microbiol | 2020 Apr |
Microbial prevalence, diversity and abundance in amniotic fluid during preterm labor: a molecular and culture-based investigation. | DiGiulio DB, Romero R, Amogan HP, Kusanovic JP, Bik EM, Gotsch F, Kim CJ, Erez O, Edwin S, Relman DA | PloS one | 18725970 | PLoS One | 2008 Aug 26 |
The Landscape Ecology and Microbiota of the Human Nose, Mouth, and Throat. | Proctor DM, Relman DA | Cell host & microbe | 28407480 | Cell Host Microbe | 2017 Apr 12 |
Genetically dictated change in host mucus carbohydrate landscape exerts a diet-dependent effect on the gut microbiota. | Kashyap PC, Marcobal A, Ursell LK, Smits SA, Sonnenburg ED, Costello EK, Higginbottom SK, Domino SE, Holmes SP, Relman DA, Knight R, Gordon JI, Sonnenburg JL | Proceedings of the National Academy of Sciences of the United States of America | 24062455 | Proc Natl Acad Sci U S A | 2013 Oct 15 |
Distinct distal gut microbiome diversity and composition in healthy children from Bangladesh and the United States. | Lin A, Bik EM, Costello EK, Dethlefsen L, Haque R, Relman DA, Singh U | PloS one | 23349750 | PLoS One | 2013 |
Physics. Measuring mass in seconds. | Debs JE, Robins NP, Close JD | Science (New York, N.Y.) | 23372004 | Science | 2013 Feb 1 |
The human microbiome: ecosystem resilience and health. | Relman DA | Nutrition reviews | 22861804 | Nutr Rev | 2012 Aug |
SmashCell: a software framework for the analysis of single-cell amplified genome sequences. | Harrington ED, Arumugam M, Raes J, Bork P, Relman DA | Bioinformatics (Oxford, England) | 20966005 | Bioinformatics | 2010 Dec 1 |
Variation in Taxonomic Composition of the Fecal Microbiota in an Inbred Mouse Strain across Individuals and Time. | Hoy YE, Bik EM, Lawley TD, Holmes SP, Monack DM, Theriot JA, Relman DA | PloS one | 26565698 | PLoS One | 2015 |
A spatial gradient of bacterial diversity in the human oral cavity shaped by salivary flow. | Proctor DM, Fukuyama JA, Loomer PM, Armitage GC, Lee SA, Davis NM, Ryder MI, Holmes SP, Relman DA | Nature communications | 29445174 | Nat Commun | 2018 Feb 14 |
Microbiology. Undernutrition--looking within for answers. | Relman DA | Science (New York, N.Y.) | 23363770 | Science | 2013 Feb 1 |
Metagenomic detection of phage-encoded platelet-binding factors in the human oral cavity. | Willner D, Furlan M, Schmieder R, Grasis JA, Pride DT, Relman DA, Angly FE, McDole T, Mariella RP Jr, Rohwer F, Haynes M | Proceedings of the National Academy of Sciences of the United States of America | 20547834 | Proc Natl Acad Sci U S A | 2011 Mar 15 |
Bacterial diversity in the oral cavity of 10 healthy individuals. | Bik EM, Long CD, Armitage GC, Loomer P, Emerson J, Mongodin EF, Nelson KE, Gill SR, Fraser-Liggett CM, Relman DA | The ISME journal | 20336157 | ISME J | 2010 Aug |
Strain-resolved community genomic analysis of gut microbial colonization in a premature infant. | Morowitz MJ, Denef VJ, Costello EK, Thomas BC, Poroyko V, Relman DA, Banfield JF | Proceedings of the National Academy of Sciences of the United States of America | 21191099 | Proc Natl Acad Sci U S A | 2011 Jan 18 |
Evidence of a robust resident bacteriophage population revealed through analysis of the human salivary virome. | Pride DT, Salzman J, Haynes M, Rohwer F, Davis-Long C, White RA 3rd, Loomer P, Armitage GC, Relman DA | The ISME journal | 22158393 | ISME J | 2012 May |
Microbiota-targeted therapies: an ecological perspective. | Lemon KP, Armitage GC, Relman DA, Fischbach MA | Science translational medicine | 22674555 | Sci Transl Med | 2012 Jun 6 |
The application of ecological theory toward an understanding of the human microbiome. | Costello EK, Stagaman K, Dethlefsen L, Bohannan BJ, Relman DA | Science (New York, N.Y.) | 22674335 | Science | 2012 Jun 8 |
Gut immune maturation depends on colonization with a host-specific microbiota. | Chung H, Pamp SJ, Hill JA, Surana NK, Edelman SM, Troy EB, Reading NC, Villablanca EJ, Wang S, Mora JR, Umesaki Y, Mathis D, Benoist C, Relman DA, Kasper DL | Cell | 22726443 | Cell | 2012 Jun 22 |
Microbiota's 'little helpers': bacteriophages and antibiotic-associated responses in the gut microbiome. | Sun CL, Relman DA | Genome biology | 23906048 | Genome Biol | 2013 Jul 30 |
'Til death do us part': coming to terms with symbiotic relationships. Forward. | Relman DA | Nature reviews. Microbiology | 19086265 | Nat Rev Microbiol | 2008 Oct |
Nasal microenvironments and interspecific interactions influence nasal microbiota complexity and S. aureus carriage. | Yan M, Pamp SJ, Fukuyama J, Hwang PH, Cho DY, Holmes S, Relman DA | Cell host & microbe | 24331461 | Cell Host Microbe | 2013 Dec 11 |
Microbial invasion of the amniotic cavity in pregnancies with small-for-gestational-age fetuses. | DiGiulio DB, Gervasi MT, Romero R, Vaisbuch E, Mazaki-Tovi S, Kusanovic JP, Seok KS, Gómez R, Mittal P, Gotsch F, Chaiworapongsa T, Oyarzún E, Kim CJ, Relman DA | Journal of perinatal medicine | 20482466 | J Perinat Med | 2010 Sep |
Prevalence and diversity of microbes in the amniotic fluid, the fetal inflammatory response, and pregnancy outcome in women with preterm pre-labor rupture of membranes. | DiGiulio DB, Romero R, Kusanovic JP, Gómez R, Kim CJ, Seok KS, Gotsch F, Mazaki-Tovi S, Vaisbuch E, Sanders K, Bik EM, Chaiworapongsa T, Oyarzún E, Relman DA | American journal of reproductive immunology (New York, N.Y. : 1989) | 20331587 | Am J Reprod Immunol | 2010 Jul 1 |
Single-cell sequencing provides clues about the host interactions of segmented filamentous bacteria (SFB). | Pamp SJ, Harrington ED, Quake SR, Relman DA, Blainey PC | Genome research | 22434425 | Genome Res | 2012 Jun |
Linking microbial phylogeny to metabolic activity at the single-cell level by using enhanced element labeling-catalyzed reporter deposition fluorescence in situ hybridization (EL-FISH) and NanoSIMS. | Behrens S, Lösekann T, Pett-Ridge J, Weber PK, Ng WO, Stevenson BS, Hutcheon ID, Relman DA, Spormann AM | Applied and environmental microbiology | 18359832 | Appl Environ Microbiol | 2008 May |
Comparisons of distance methods for combining covariates and abundances in microbiome studies. | Fukuyama J, McMurdie PJ, Dethlefsen L, Relman DA, Holmes S | Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing | 22174277 | Pac Symp Biocomput | 2012 |
The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing. | Dethlefsen L, Huse S, Sogin ML, Relman DA | PLoS biology | 19018661 | PLoS Biol | 2008 Nov 18 |
Exploring microbial diversity and taxonomy using SSU rRNA hypervariable tag sequencing. | Huse SM, Dethlefsen L, Huber JA, Mark Welch D, Relman DA, Sogin ML | PLoS genetics | 19023400 | PLoS Genet | 2008 Nov |
Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation. | Dethlefsen L, Relman DA | Proceedings of the National Academy of Sciences of the United States of America | 20847294 | Proc Natl Acad Sci U S A | 2011 Mar 15 |
Microbial genomics and infectious diseases. | Relman DA | The New England journal of medicine | 21793746 | N Engl J Med | 2011 Jul 28 |
Time series community genomics analysis reveals rapid shifts in bacterial species, strains, and phage during infant gut colonization. | Sharon I, Morowitz MJ, Thomas BC, Costello EK, Relman DA, Banfield JF | Genome research | 22936250 | Genome Res | 2013 Jan |
A career pathway in protein folding: from model peptides to postreductionist protein science. | Gierasch LM | Protein science : a publication of the Protein Society | 21404361 | Protein Sci | 2011 May |
A method for direct measurement of protein stability in vivo. | Ignatova Z, Gierasch LM | Methods in molecular biology (Clifton, N.J.) | 19157083 | Methods Mol Biol | 2009 |
Unique physical properties and interactions of the domains of methylated DNA binding protein 2. | Ghosh RP, Nikitina T, Horowitz-Scherer RA, Gierasch LM, Uversky VN, Hite K, Hansen JC, Woodcock CL | Biochemistry | 20405910 | Biochemistry | 2010 May 25 |
Using a low denaturant model to explore the conformational features of translocation-active SecA. | Maki JL, Krishnan B, Gierasch LM | Biochemistry | 22304380 | Biochemistry | 2012 Feb 21 |
Site-specific fluorescent labeling of poly-histidine sequences using a metal-chelating cysteine. | Krishnan B, Szymanska A, Gierasch LM | Chemical biology & drug design | 17313455 | Chem Biol Drug Des | 2007 Jan |
Protein folding in the cell: challenges and progress. | Gershenson A, Gierasch LM | Current opinion in structural biology | 21112769 | Curr Opin Struct Biol | 2011 Feb |
Macromolecular crowding remodels the energy landscape of a protein by favoring a more compact unfolded state. | Hong J, Gierasch LM | Journal of the American Chemical Society | 20662522 | J Am Chem Soc | 2010 Aug 4 |
How bacteria survive an acid trip. | Hingorani KS, Gierasch LM | Proceedings of the National Academy of Sciences of the United States of America | 23530238 | Proc Natl Acad Sci U S A | 2013 Apr 2 |
Early folding events protect aggregation-prone regions of a β-rich protein. | Budyak IL, Krishnan B, Marcelino-Cruz AM, Ferrolino MC, Zhuravleva A, Gierasch LM | Structure (London, England : 1993) | 23454187 | Structure | 2013 Mar 5 |
Sending signals dynamically. | Smock RG, Gierasch LM | Science (New York, N.Y.) | 19359576 | Science | 2009 Apr 10 |
Celebrating the scientific legacy of Elkan R. Blout. | Gierasch LM, Deber CM, Brodsky B | Biopolymers | 18307218 | Biopolymers | 2008 May |
Chapter 3: A fluorescent window into protein folding and aggregation in cells. | Ignatova Z, Gierasch LM | Methods in cell biology | 19118672 | Methods Cell Biol | 2008 |
Delicate balance between functionally required flexibility and aggregation risk in a β-rich protein. | Ferrolino MC, Zhuravleva A, Budyak IL, Krishnan B, Gierasch LM | Biochemistry | 24236614 | Biochemistry | 2013 Dec 10 |
Dynamic local unfolding in the serpin α-1 antitrypsin provides a mechanism for loop insertion and polymerization. | Krishnan B, Gierasch LM | Nature structural & molecular biology | 21258324 | Nat Struct Mol Biol | 2011 Feb |
Post-reductionist protein science, or putting Humpty Dumpty back together again. | Gierasch LM, Gershenson A | Nature chemical biology | 19841622 | Nat Chem Biol | 2009 Nov |
The molecular dating game: an antibody heavy chain hangs loose with a chaperone while waiting for its life partner. | Hebert DN, Gierasch LM | Molecular cell | 19560414 | Mol Cell | 2009 Jun 26 |
Comparing protein folding in vitro and in vivo: foldability meets the fitness challenge. | Hingorani KS, Gierasch LM | Current opinion in structural biology | 24434632 | Curr Opin Struct Biol | 2014 Feb |
Effects of osmolytes on protein folding and aggregation in cells. | Ignatova Z, Gierasch LM | Methods in enzymology | 17875429 | Methods Enzymol | 2007 |
Expression and Purification of Active Recombinant Human Alpha-1 Antitrypsin (AAT) from Escherichia coli. | Krishnan B, Hedstrom L, Hebert DN, Gierasch LM, Gershenson A | Methods in molecular biology (Clifton, N.J.) | 28752459 | Methods Mol Biol | 2017 |
Rett syndrome-causing mutations in human MeCP2 result in diverse structural changes that impact folding and DNA interactions. | Ghosh RP, Horowitz-Scherer RA, Nikitina T, Gierasch LM, Woodcock CL | The Journal of biological chemistry | 18499664 | J Biol Chem | 2008 Jul 18 |
Orthogonal cross-seeding: an approach to explore protein aggregates in living cells. | Hinz J, Gierasch LM, Ignatova Z | Biochemistry | 18330996 | Biochemistry | 2008 Apr 8 |
FoldEco: a model for proteostasis in E. coli. | Powers ET, Powers DL, Gierasch LM | Cell reports | 22509487 | Cell Rep | 2012 Mar 29 |
Cross-strand split tetra-Cys motifs as structure sensors in a beta-sheet protein. | Krishnan B, Gierasch LM | Chemistry & biology | 18940670 | Chem Biol | 2008 Oct 20 |
Roles of beta-turns in protein folding: from peptide models to protein engineering. | Marcelino AM, Gierasch LM | Biopolymers | 18275088 | Biopolymers | 2008 May |
Nature's molecular sponges: small heat shock proteins grow into their chaperone roles. | Eyles SJ, Gierasch LM | Proceedings of the National Academy of Sciences of the United States of America | 20133678 | Proc Natl Acad Sci U S A | 2010 Feb 16 |
Its preferential interactions with biopolymers account for diverse observed effects of trehalose. | Hong J, Gierasch LM, Liu Z | Biophysical journal | 26153711 | Biophys J | 2015 Jul 7 |
The Role of Aromatic-Aromatic Interactions in Strand-Strand Stabilization of β-Sheets. | Budyak IL, Zhuravleva A, Gierasch LM | Journal of molecular biology | 23810905 | J Mol Biol | 2013 Sep 23 |
How one bad protein spoils the barrel: structural details of β2-microglobulin amyloidogenicity. | Gierasch LM | Molecular cell | 21255721 | Mol Cell | 2011 Jan 21 |
In-cell aggregation of a polyglutamine-containing chimera is a multistep process initiated by the flanking sequence. | Ignatova Z, Thakur AK, Wetzel R, Gierasch LM | The Journal of biological chemistry | 17942400 | J Biol Chem | 2007 Dec 14 |
From the test tube to the cell: exploring the folding and aggregation of a beta-clam protein. | Ignatova Z, Krishnan B, Bombardier JP, Marcelino AM, Hong J, Gierasch LM | Biopolymers | 17206628 | Biopolymers | 2007 |
Exploring weak, transient protein--protein interactions in crowded in vivo environments by in-cell nuclear magnetic resonance spectroscopy. | Wang Q, Zhuravleva A, Gierasch LM | Biochemistry | 21942871 | Biochemistry | 2011 Nov 1 |
p53 regulates Period2 expression and the circadian clock. | Miki T, Matsumoto T, Zhao Z, Lee CC | Nature communications | 24051492 | Nat Commun | 2013 |
AMP deaminase 3 deficiency enhanced 5'-AMP induction of hypometabolism. | Daniels IS, O Brien WG 3rd, Nath V, Zhao Z, Lee CC | PloS one | 24066180 | PLoS One | 2013 |
Hepatic gene expression profiling of 5'-AMP-induced hypometabolism in mice. | Zhao Z, Miki T, Van Oort-Jansen A, Matsumoto T, Loose DS, Lee CC | Physiological genomics | 21224422 | Physiol Genomics | 2011 Apr 12 |
New insights on the regulation of the adenine nucleotide pool of erythrocytes in mouse models. | O'Brien WG 3rd, Ling HS, Zhao Z, Lee CC | PloS one | 28746349 | PLoS One | 2017 |
Metabolite Profiling of 5'-AMP-Induced Hypometabolism. | Zhao Z, Van Oort A, Tao Z, O'Brien WG 3rd, Lee CC | Metabolomics : Official journal of the Metabolomic Society | 24511307 | Metabolomics | 2014 Feb 1 |
The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome. | He B, Nohara K, Park N, Park YS, Guillory B, Zhao Z, Garcia JM, Koike N, Lee CC, Takahashi JS, Yoo SH, Chen Z | Cell metabolism | 27076076 | Cell Metab | 2016 Apr 12 |
A role of erythrocytes in adenosine monophosphate initiation of hypometabolism in mammals. | Daniels IS, Zhang J, O'Brien WG 3rd, Tao Z, Miki T, Zhao Z, Blackburn MR, Lee CC | The Journal of biological chemistry | 20430891 | J Biol Chem | 2010 Jul 2 |
Numb links extracellular cues to intracellular polarity machinery to promote chemotaxis. | Zhou P, Alfaro J, Chang EH, Zhao X, Porcionatto M, Segal RA | Developmental cell | 21571219 | Dev Cell | 2011 May 17 |
Heparan sulfate proteoglycans containing a glypican 5 core and 2-O-sulfo-iduronic acid function as Sonic Hedgehog co-receptors to promote proliferation. | Witt RM, Hecht ML, Pazyra-Murphy MF, Cohen SM, Noti C, van Kuppevelt TH, Fuller M, Chan JA, Hopwood JJ, Seeberger PH, Segal RA | The Journal of biological chemistry | 23867465 | J Biol Chem | 2013 Sep 6 |
Olfactory behavioral testing in the adult mouse. | Witt RM, Galligan MM, Despinoy JR, Segal R | Journal of visualized experiments : JoVE | 19229182 | J Vis Exp | 2009 Jan 28 |
Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses. | Chan JA, Balasubramanian S, Witt RM, Nazemi KJ, Choi Y, Pazyra-Murphy MF, Walsh CO, Thompson M, Segal RA | Nature neuroscience | 19287388 | Nat Neurosci | 2009 Apr |
Shh-proteoglycan interactions regulate maturation of olfactory glomerular circuitry. | Persson L, Witt RM, Galligan M, Greer PL, Eisner A, Pazyra-Murphy MF, Datta SR, Segal RA | Developmental neurobiology | 24913191 | Dev Neurobiol | 2014 Dec |
Nonlytic viral spread enhanced by autophagy components. | Bird SW, Maynard ND, Covert MW, Kirkegaard K | Proceedings of the National Academy of Sciences of the United States of America | 25157142 | Proc Natl Acad Sci U S A | 2014 Sep 9 |
Dominant drug targets suppress the emergence of antiviral resistance. | Tanner EJ, Liu HM, Oberste MS, Pallansch M, Collett MS, Kirkegaard K | eLife | 25365453 | Elife | 2014 Nov 3 |
Interstitial contacts in an RNA-dependent RNA polymerase lattice. | Tellez AB, Wang J, Tanner EJ, Spagnolo JF, Kirkegaard K, Bullitt E | Journal of molecular biology | 21839092 | J Mol Biol | 2011 Sep 30 |
The ins and outs of viral infection: keystone meeting review. | Bird SW, Kirkegaard K, Agbandje-McKenna M, Freed EO | Viruses | 25256395 | Viruses | 2014 Sep 25 |
Detection and Differentiation of Multiple Viral RNAs Using Branched DNA FISH Coupled to Confocal Microscopy and Flow Cytometry. | van Buuren N, Kirkegaard K | Bio-protocol | 30505886 | Bio Protoc | 2018 Oct 20 |
Neuron-to-neuron transmission of α-synuclein fibrils through axonal transport. | Freundt EC, Maynard N, Clancy EK, Roy S, Bousset L, Sourigues Y, Covert M, Melki R, Kirkegaard K, Brahic M | Annals of neurology | 23109146 | Ann Neurol | 2012 Oct |
The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus. | Gomez JA, Wapinski OL, Yang YW, Bureau JF, Gopinath S, Monack DM, Chang HY, Brahic M, Kirkegaard K | Cell | 23415224 | Cell | 2013 Feb 14 |
Exploiting Genetic Interference for Antiviral Therapy. | Tanner EJ, Kirkegaard KA, Weinberger LS | PLoS genetics | 27149616 | PLoS Genet | 2016 May |
Nonlytic spread of naked viruses. | Bird SW, Kirkegaard K | Autophagy | 25680079 | Autophagy | 2015 |
A computational model predicts Xenopus meiotic spindle organization. | Loughlin R, Heald R, Nédélec F | The Journal of cell biology | 21173114 | J Cell Biol | 2010 Dec 27 |
Katanin contributes to interspecies spindle length scaling in Xenopus. | Loughlin R, Wilbur JD, McNally FJ, Nédélec FJ, Heald R | Cell | 22153081 | Cell | 2011 Dec 9 |
Mitotic chromosome size scaling in Xenopus. | Kieserman EK, Heald R | Cell cycle (Georgetown, Tex.) | 22071695 | Cell Cycle | 2011 Nov 15 |
Nuclear size is regulated by importin α and Ntf2 in Xenopus. | Levy DL, Heald R | Cell | 20946986 | Cell | 2010 Oct 15 |
Mechanisms of intracellular scaling. | Levy DL, Heald R | Annual review of cell and developmental biology | 22804576 | Annu Rev Cell Dev Biol | 2012 |
Mechanisms of mitotic spindle assembly and function. | Walczak CE, Heald R | International review of cytology | 18275887 | Int Rev Cytol | 2008 |
Molecular cloaking of H2A.Z on mortal DNA chromosomes during nonrandom segregation. | Huh YH, Sherley JL | Stem cells (Dayton, Ohio) | 21905168 | Stem Cells | 2011 Oct |
Ex vivo Expansion of Human Adult Pancreatic Cells with Properties of Distributed Stem Cells by Suppression of Asymmetric Cell Kinetics. | Paré J, Sherley J | Journal of stem cell research & therapy | 25197614 | J Stem Cell Res Ther | 2013 Sep |
CXCR6, a newly defined biomarker of tissue-specific stem cell asymmetric self-renewal, identifies more aggressive human melanoma cancer stem cells. | Taghizadeh R, Noh M, Huh YH, Ciusani E, Sigalotti L, Maio M, Arosio B, Nicotra MR, Natali P, Sherley JL, La Porta CA | PloS one | 21203549 | PLoS One | 2010 Dec 22 |
Decreased H3K27 and H3K4 trimethylation on mortal chromosomes in distributed stem cells. | Huh YH, Sherley JL | Cell death & disease | 25476902 | Cell Death Dis | 2014 Dec 4 |
A new mechanism for aging: chemical "age spots" in immortal DNA strands in distributed stem cells. | Sherley JL | Breast disease | 19029623 | Breast Dis | 2008 |
Culture environment-induced pluripotency of SACK-expanded tissue stem cells. | Paré JF, Sherley JL | Journal of biomedicine & biotechnology | 22523467 | J Biomed Biotechnol | 2011 |
Higher 5-hydroxymethylcytosine identifies immortal DNA strand chromosomes in asymmetrically self-renewing distributed stem cells. | Huh YH, Cohen J, Sherley JL | Proceedings of the National Academy of Sciences of the United States of America | 24082118 | Proc Natl Acad Sci U S A | 2013 Oct 15 |
Sparse feature selection identifies H2A.Z as a novel, pattern-specific biomarker for asymmetrically self-renewing distributed stem cells. | Huh YH, Noh M, Burden FR, Chen JC, Winkler DA, Sherley JL | Stem cell research | 25636161 | Stem Cell Res | 2015 Mar |
A resource for discovering specific and universal biomarkers for distributed stem cells. | Noh M, Smith JL, Huh YH, Sherley JL | PloS one | 21818293 | PLoS One | 2011 |
Bacterial nitric-oxide synthases operate without a dedicated redox partner. | Gusarov I, Starodubtseva M, Wang ZQ, McQuade L, Lippard SJ, Stuehr DJ, Nudler E | The Journal of biological chemistry | 18316370 | J Biol Chem | 2008 May 9 |
Endogenous nitric oxide protects bacteria against a wide spectrum of antibiotics. | Gusarov I, Shatalin K, Starodubtseva M, Nudler E | Science (New York, N.Y.) | 19745150 | Science | 2009 Sep 11 |
Bacillus anthracis-derived nitric oxide is essential for pathogen virulence and survival in macrophages. | Shatalin K, Gusarov I, Avetissova E, Shatalina Y, McQuade LE, Lippard SJ, Nudler E | Proceedings of the National Academy of Sciences of the United States of America | 18215992 | Proc Natl Acad Sci U S A | 2008 Jan 22 |
Inorganic nanoparticle-based contrast agents for molecular imaging. | Cho EC, Glaus C, Chen J, Welch MJ, Xia Y | Trends in molecular medicine | 21074494 | Trends Mol Med | 2010 Dec |
Quantitative analysis of the role played by poly(vinylpyrrolidone) in seed-mediated growth of Ag nanocrystals. | Xia X, Zeng J, Oetjen LK, Li Q, Xia Y | Journal of the American Chemical Society | 22206387 | J Am Chem Soc | 2012 Jan 25 |
Surface-enhanced Raman scattering: comparison of three different molecules on single-crystal nanocubes and nanospheres of silver. | Rycenga M, Kim MH, Camargo PH, Cobley C, Li ZY, Xia Y | The journal of physical chemistry. A | 19175302 | J Phys Chem A | 2009 Apr 23 |
Shape-controlled synthesis of metal nanocrystals: simple chemistry meets complex physics? | Xia Y, Xiong Y, Lim B, Skrabalak SE | Angewandte Chemie (International ed. in English) | 19053095 | Angew Chem Int Ed Engl | 2009 |
Dimers of silver nanospheres: facile synthesis and their use as hot spots for surface-enhanced Raman scattering. | Li W, Camargo PH, Lu X, Xia Y | Nano letters | 19143509 | Nano Lett | 2009 Jan |
A simple spectroscopic method for differentiating cellular uptakes of gold nanospheres and nanorods from their mixtures. | Cho EC, Liu Y, Xia Y | Angewandte Chemie (International ed. in English) | 20146292 | Angew Chem Int Ed Engl | 2010 Mar 8 |
In vitro mineralization by preosteoblasts in poly(DL-lactide-co-glycolide) inverse opal scaffolds reinforced with hydroxyapatite nanoparticles. | Choi SW, Zhang Y, Thomopoulos S, Xia Y | Langmuir : the ACS journal of surfaces and colloids | 20450216 | Langmuir | 2010 Jul 20 |
Facile synthesis of gold icosahedra in an aqueous solution by reacting HAuCl(4) with N-vinyl pyrrolidone. | Yavuz MS, Li W, Xia Y | Chemistry (Weinheim an der Bergstrasse, Germany) | 19876970 | Chemistry | 2009 Dec 7 |
Gold nanocages covered by smart polymers for controlled release with near-infrared light. | Yavuz MS, Cheng Y, Chen J, Cobley CM, Zhang Q, Rycenga M, Xie J, Kim C, Song KH, Schwartz AG, Wang LV, Xia Y | Nature materials | 19881498 | Nat Mater | 2009 Dec |
Probing the photothermal effect of gold-based nanocages with surface-enhanced Raman scattering (SERS). | Rycenga M, Wang Z, Gordon E, Cobley CM, Schwartz AG, Lo CS, Xia Y | Angewandte Chemie (International ed. in English) | 20014343 | Angew Chem Int Ed Engl | 2009 |
Measuring the surface-enhanced Raman scattering enhancement factors of hot spots formed between an individual Ag nanowire and a single Ag nanocube. | Camargo PH, Cobley CM, Rycenga M, Xia Y | Nanotechnology | 19801754 | Nanotechnology | 2009 Oct 28 |
Fabrication of Microbeads with a Controllable Hollow Interior and Porous Wall Using a Capillary Fluidic Device. | Choi SW, Zhang Y, Xia Y | Advanced functional materials | 20191106 | Adv Funct Mater | 2009 Sep 23 |
A bioreducible polymer for efficient delivery of Fas-silencing siRNA into stem cell spheroids and enhanced therapeutic angiogenesis. | Shim MS, Bhang SH, Yoon K, Choi K, Xia Y | Angewandte Chemie (International ed. in English) | 23074025 | Angew Chem Int Ed Engl | 2012 Nov 19 |
Investigation of neovascularization in three-dimensional porous scaffolds in vivo by a combination of multiscale photoacoustic microscopy and optical coherence tomography. | Cai X, Zhang Y, Li L, Choi SW, MacEwan MR, Yao J, Kim C, Xia Y, Wang LV | Tissue engineering. Part C, Methods | 22838500 | Tissue Eng Part C Methods | 2013 Mar |
Immuno gold nanocages with tailored optical properties for targeted photothermal destruction of cancer cells. | Chen J, Wang D, Xi J, Au L, Siekkinen A, Warsen A, Li ZY, Zhang H, Xia Y, Li X | Nano letters | 17430005 | Nano Lett | 2007 May |
Gold nanocages for cancer detection and treatment. | Skrabalak SE, Au L, Lu X, Li X, Xia Y | Nanomedicine (London, England) | 17976028 | Nanomedicine (Lond) | 2007 Oct |
Chronic label-free volumetric photoacoustic microscopy of melanoma cells in three-dimensional porous scaffolds. | Zhang Y, Cai X, Choi SW, Kim C, Wang LV, Xia Y | Biomaterials | 20727581 | Biomaterials | 2010 Nov |
Phase-Change Materials for Controlled Release and Related Applications. | Qiu J, Huo D, Xia Y | Advanced materials (Deerfield Beach, Fla.) | 32383215 | Adv Mater | 2020 Jun |
Electrospun Nanofibers: New Concepts, Materials, and Applications. | Xue J, Xie J, Liu W, Xia Y | Accounts of chemical research | 28777535 | Acc Chem Res | 2017 Aug 15 |
Inverse Opal Scaffolds and Their Biomedical Applications. | Zhang YS, Zhu C, Xia Y | Advanced materials (Deerfield Beach, Fla.) | 28649794 | Adv Mater | 2017 Sep |
Using well-defined Ag nanocubes as substrates to quantify the spatial resolution and penetration depth of surface-enhanced Raman scattering imaging. | Moran CH, Rycenga M, Xia X, Cobley CM, Xia Y | Nanotechnology | 24334508 | Nanotechnology | 2014 Jan 10 |
Multiple facets for extracellular matrix mimicking in regenerative medicine. | Zhang YS, Xia Y | Nanomedicine (London, England) | 25816873 | Nanomedicine (Lond) | 2015 |
Gold Nanocages: A Novel Class of Multifunctional Nanomaterials for Theranostic Applications. | Chen J, Yang M, Zhang Q, Cho EC, Cobley CM, Kim C, Glaus C, Wang LV, Welch MJ, Xia Y | Advanced functional materials | 33907543 | Adv Funct Mater | 2010 Nov 9 |
Correlated Rayleigh Scattering Spectroscopy and Scanning Electron Microscopy Studies of Au-Ag Bimetallic Nanoboxes and Nanocages. | Hu M, Chen J, Marquez M, Xia Y, Hartland GV | The journal of physical chemistry. C, Nanomaterials and interfaces | 18629346 | J Phys Chem C Nanomater Interfaces | 2007 |
Dark-field microscopy studies of single metal nanoparticles: understanding the factors that influence the linewidth of the localized surface plasmon resonance. | Hu M, Novo C, Funston A, Wang H, Staleva H, Zou S, Mulvaney P, Xia Y, Hartland GV | Journal of materials chemistry | 18846243 | J Mater Chem | 2008 |
Etching and growth: an intertwined pathway to silver nanocrystals with exotic shapes. | Cobley CM, Rycenga M, Zhou F, Li ZY, Xia Y | Angewandte Chemie (International ed. in English) | 19479923 | Angew Chem Int Ed Engl | 2009 |
Nanomaterial-Enabled Photothermal Heating and Its Use for Cancer Therapy via Localized Hyperthermia. | Shen S, Qiu J, Huo D, Xia Y | Small (Weinheim an der Bergstrasse, Germany) | 37803412 | Small | 2024 Feb |
A facile synthesis of asymmetric hybrid colloidal particles. | Ohnuma A, Cho EC, Camargo PH, Au L, Ohtani B, Xia Y | Journal of the American Chemical Society | 19140763 | J Am Chem Soc | 2009 Feb 4 |
Non-invasive and in situ characterization of the degradation of biomaterial scaffolds by volumetric photoacoustic microscopy. | Zhang YS, Cai X, Yao J, Xing W, Wang LV, Xia Y | Angewandte Chemie (International ed. in English) | 24130155 | Angew Chem Int Ed Engl | 2014 Jan 3 |
The mechanics of PLGA nanofiber scaffolds with biomimetic gradients in mineral for tendon-to-bone repair. | Lipner J, Liu W, Liu Y, Boyle J, Genin GM, Xia Y, Thomopoulos S | Journal of the mechanical behavior of biomedical materials | 25194525 | J Mech Behav Biomed Mater | 2014 Dec |
Gold Nanomaterials at Work in Biomedicine. | Yang X, Yang M, Pang B, Vara M, Xia Y | Chemical reviews | 26293344 | Chem Rev | 2015 Oct 14 |
In Vivo Evaluation of Adipose-Derived Stromal Cells Delivered with a Nanofiber Scaffold for Tendon-to-Bone Repair. | Lipner J, Shen H, Cavinatto L, Liu W, Havlioglu N, Xia Y, Galatz LM, Thomopoulos S | Tissue engineering. Part A | 26414599 | Tissue Eng Part A | 2015 Nov |
Dissolving Ag from Au-Ag Alloy Nanoboxes with H(2)O(2): A Method for Both Tailoring the Optical Properties and Measuring the H(2)O(2) Concentration. | Zhang Q, Cobley CM, Zeng J, Wen LP, Chen J, Xia Y | The journal of physical chemistry. C, Nanomaterials and interfaces | 20495675 | J Phys Chem C Nanomater Interfaces | 2010 Mar 5 |
Facile synthesis of Ag nanocubes of 30 to 70 nm in edge length with CF(3)COOAg as a precursor. | Zhang Q, Li W, Wen LP, Chen J, Xia Y | Chemistry (Weinheim an der Bergstrasse, Germany) | 20593441 | Chemistry | 2010 Sep 3 |
Electrospun nanofibers for neural tissue engineering. | Xie J, MacEwan MR, Schwartz AG, Xia Y | Nanoscale | 20648362 | Nanoscale | 2010 Jan |
Nanofiber membranes with controllable microwells and structural cues and their use in forming cell microarrays and neuronal networks. | Xie J, Liu W, MacEwan MR, Yeh YC, Thomopoulos S, Xia Y | Small (Weinheim an der Bergstrasse, Germany) | 21294253 | Small | 2011 Feb 7 |
Quantifying the cellular uptake of antibody-conjugated Au nanocages by two-photon microscopy and inductively coupled plasma mass spectrometry. | Au L, Zhang Q, Cobley CM, Gidding M, Schwartz AG, Chen J, Xia Y | ACS nano | 19954236 | ACS Nano | 2010 Jan 26 |
The effect of sedimentation and diffusion on cellular uptake of gold nanoparticles. | Cho EC, Zhang Q, Xia Y | Nature nanotechnology | 21516092 | Nat Nanotechnol | 2011 Apr 24 |
Gold nanocages: from synthesis to theranostic applications. | Xia Y, Li W, Cobley CM, Chen J, Xia X, Zhang Q, Yang M, Cho EC, Brown PK | Accounts of chemical research | 21528889 | Acc Chem Res | 2011 Oct 18 |
Improving biomedical imaging with gold nanocages. | Xia Y, Skrabalak SE | SPIE newsroom | 19704778 | SPIE Newsroom | 2008 May 12 |
Production of Ag nanocubes on a scale of 0.1 g per batch by protecting the NaHS-mediated polyol synthesis with argon. | Zhang Q, Cobley C, Au L, McKiernan M, Schwartz A, Wen LP, Chen J, Xia Y | ACS applied materials & interfaces | 20305725 | ACS Appl Mater Interfaces | 2009 Sep |
Understanding the SERS Effects of Single Silver Nanoparticles and Their Dimers, One at a Time. | Rycenga M, Camargo PH, Li W, Moran CH, Xia Y | The journal of physical chemistry letters | 20368749 | J Phys Chem Lett | 2010 Feb 18 |
Colloidal hollow spheres of conducting polymers with smooth surface and uniform, controllable sizes. | Bai MY, Cheng YJ, Wickline SA, Xia Y | Small (Weinheim an der Bergstrasse, Germany) | 19384880 | Small | 2009 Aug 3 |
Three-dimensional scaffolds for tissue engineering: the importance of uniformity in pore size and structure. | Choi SW, Zhang Y, Xia Y | Langmuir : the ACS journal of surfaces and colloids | 21090781 | Langmuir | 2010 Dec 21 |
Morphological Evolution of Single-Crystal Ag Nanospheres during the Galvanic Replacement Reaction with HAuCl(4). | Kim MH, Lu X, Wiley B, Lee EP, Xia Y | The journal of physical chemistry. C, Nanomaterials and interfaces | 18787649 | J Phys Chem C Nanomater Interfaces | 2008 |
Photoacoustic tomography of a rat cerebral cortex in vivo with au nanocages as an optical contrast agent. | Yang X, Skrabalak SE, Li ZY, Xia Y, Wang LV | Nano letters | 18020475 | Nano Lett | 2007 Dec |
Facile synthesis of tadpole-like nanostructures consisting of Au heads and Pd tails. | Camargo PH, Xiong Y, Ji L, Zuo JM, Xia Y | Journal of the American Chemical Society | 18027954 | J Am Chem Soc | 2007 Dec 19 |
In vivo quantitative evaluation of the transport kinetics of gold nanocages in a lymphatic system by noninvasive photoacoustic tomography. | Cai X, Li W, Kim CH, Yuan Y, Wang LV, Xia Y | ACS nano | 22054348 | ACS Nano | 2011 Dec 27 |
Quantifying the coverage density of poly(ethylene glycol) chains on the surface of gold nanostructures. | Xia X, Yang M, Wang Y, Zheng Y, Li Q, Chen J, Xia Y | ACS nano | 22148912 | ACS Nano | 2012 Jan 24 |
Radioluminescent gold nanocages with controlled radioactivity for real-time in vivo imaging. | Wang Y, Liu Y, Luehmann H, Xia X, Wan D, Cutler C, Xia Y | Nano letters | 23360442 | Nano Lett | 2013 Feb 13 |
Comparison study of gold nanohexapods, nanorods, and nanocages for photothermal cancer treatment. | Wang Y, Black KC, Luehmann H, Li W, Zhang Y, Cai X, Wan D, Liu SY, Li M, Kim P, Li ZY, Wang LV, Liu Y, Xia Y | ACS nano | 23383982 | ACS Nano | 2013 Mar 26 |
Neovascularization in biodegradable inverse opal scaffolds with uniform and precisely controlled pore sizes. | Choi SW, Zhang Y, Macewan MR, Xia Y | Advanced healthcare materials | 23184495 | Adv Healthc Mater | 2013 Jan |
A plasmon-assisted optofluidic (PAOF) system for measuring the photothermal conversion efficiencies of gold nanostructures and controlling an electrical switch. | Zeng J, Goldfeld D, Xia Y | Angewandte Chemie (International ed. in English) | 23494970 | Angew Chem Int Ed Engl | 2013 Apr 8 |
Synthesis of Ag nanocubes 18-32 nm in edge length: the effects of polyol on reduction kinetics, size control, and reproducibility. | Wang Y, Zheng Y, Huang CZ, Xia Y | Journal of the American Chemical Society | 23317148 | J Am Chem Soc | 2013 Feb 6 |
Protein capsules with cross-linked, semipermeable, and enzyme-degradable surface barriers for controlled release. | Zhou J, Hyun DC, Liu H, Wu H, Xia Y | Macromolecular rapid communications | 24957975 | Macromol Rapid Commun | 2014 Aug |
Optical-resolution photoacoustic microscopy for volumetric and spectral analysis of histological and immunochemical samples. | Zhang YS, Yao J, Zhang C, Li L, Wang LV, Xia Y | Angewandte Chemie (International ed. in English) | 24961608 | Angew Chem Int Ed Engl | 2014 Jul 28 |
Emerging applications of phase-change materials (PCMs): teaching an old dog new tricks. | Hyun DC, Levinson NS, Jeong U, Xia Y | Angewandte Chemie (International ed. in English) | 24470287 | Angew Chem Int Ed Engl | 2014 Apr 7 |
Fabrication of Cell Patches Using Biodegradable Scaffolds with a Hexagonal Array of Interconnected Pores (SHAIPs). | Zhang YS, Yao J, Wang LV, Xia Y | Polymer | 24443593 | Polymer (Guildf) | 2014 Jan 14 |
Neurite outgrowth on electrospun nanofibers with uniaxial alignment: the effects of fiber density, surface coating, and supporting substrate. | Xie J, Liu W, MacEwan MR, Bridgman PC, Xia Y | ACS nano | 24444076 | ACS Nano | 2014 Feb 25 |
Near-infrared gold nanocages as a new class of tracers for photoacoustic sentinel lymph node mapping on a rat model. | Song KH, Kim C, Cobley CM, Xia Y, Wang LV | Nano letters | 19072058 | Nano Lett | 2009 Jan |
A SERS study of the molecular structure of alkanethiol monolayers on Ag nanocubes in the presence of aqueous glucose. | Rycenga M, McLellan JM, Xia Y | Chemical physics letters | 20160847 | Chem Phys Lett | 2009 Sep 22 |
Fine tuning the optical properties of Au-Ag nanocages by selectively etching Ag with oxygen and a water-soluble thiol. | Cho EC, Cobley CM, Rycenga M, Xia Y | Journal of materials chemistry | 19829745 | J Mater Chem | 2009 Jan 1 |
Conductive Core-Sheath Nanofibers and Their Potential Application in Neural Tissue Engineering. | Xie J, Macewan MR, Willerth SM, Li X, Moran DW, Sakiyama-Elbert SE, Xia Y | Advanced functional materials | 19830261 | Adv Funct Mater | 2009 Jul 24 |
Nerve guidance conduits based on double-layered scaffolds of electrospun nanofibers for repairing the peripheral nervous system. | Xie J, MacEwan MR, Liu W, Jesuraj N, Li X, Hunter D, Xia Y | ACS applied materials & interfaces | 24806389 | ACS Appl Mater Interfaces | 2014 Jun 25 |
Enhancing the Tactile and Near-Infrared Sensing Capabilities of Electrospun PVDF Nanofibers with the Use of Gold Nanocages. | Li H, Wu T, Xie M, Shi Y, Shen S, Zhao M, Yang X, Figueroa-Cosme LM, Ke Q, Xia Y | Journal of materials chemistry. C | 30911394 | J Mater Chem C Mater | 2018 Oct 14 |
Design and Fabrication of a Hierarchically Structured Scaffold for Tendon-to-Bone Repair. | Zhu C, Pongkitwitoon S, Qiu J, Thomopoulos S, Xia Y | Advanced materials (Deerfield Beach, Fla.) | 29534316 | Adv Mater | 2018 Apr |
Nanobottles for Controlled Release and Drug Delivery. | Qiu J, Xu J, Xia Y | Advanced healthcare materials | 32543127 | Adv Healthc Mater | 2021 Feb |
Electrospun nanofibers for regenerative medicine. | Liu W, Thomopoulos S, Xia Y | Advanced healthcare materials | 23184683 | Adv Healthc Mater | 2012 Jan 11 |
Quantitative analysis of the fate of gold nanocages in vitro and in vivo after uptake by U87-MG tumor cells. | Cho EC, Zhang Y, Cai X, Moran CM, Wang LV, Xia Y | Angewandte Chemie (International ed. in English) | 23225223 | Angew Chem Int Ed Engl | 2013 Jan 21 |
Protein-protected Au clusters as a new class of nanoscale biosensor for label-free fluorescence detection of proteases. | Wang Y, Wang Y, Zhou F, Kim P, Xia Y | Small (Weinheim an der Bergstrasse, Germany) | 22969016 | Small | 2012 Dec 21 |
Gold nanocages: synthesis, properties, and applications. | Skrabalak SE, Chen J, Sun Y, Lu X, Au L, Cobley CM, Xia Y | Accounts of chemical research | 18570442 | Acc Chem Res | 2008 Dec |
Measuring the Optical Absorption Cross-sections of Au-Ag Nanocages and Au Nanorods by Photoacoustic Imaging. | Cho EC, Kim C, Zhou F, Cobley CM, Song KH, Chen J, Li ZY, Wang LV, Xia Y | The journal of physical chemistry. C, Nanomaterials and interfaces | 19680423 | J Phys Chem C Nanomater Interfaces | 2009 May 28 |
Gold Nanocages for Biomedical Applications. | Skrabalak SE, Chen J, Au L, Lu X, Li X, Xia Y | Advanced materials (Deerfield Beach, Fla.) | 18648528 | Adv Mater | 2007 Oct 17 |
Preparation of uniform microspheres using a simple fluidic device and their crystallization into close-packed lattices. | Choi SW, Cheong IW, Kim JH, Xia Y | Small (Weinheim an der Bergstrasse, Germany) | 19189332 | Small | 2009 Apr |
A temperature-sensitive drug release system based on phase-change materials. | Choi SW, Zhang Y, Xia Y | Angewandte Chemie (International ed. in English) | 20839209 | Angew Chem Int Ed Engl | 2010 Oct 18 |
Au@Ag core-shell nanocubes with finely tuned and well-controlled sizes, shell thicknesses, and optical properties. | Ma Y, Li W, Cho EC, Li Z, Yu T, Zeng J, Xie Z, Xia Y | ACS nano | 20964400 | ACS Nano | 2010 Nov 23 |
Radially aligned, electrospun nanofibers as dural substitutes for wound closure and tissue regeneration applications. | Xie J, Macewan MR, Ray WZ, Liu W, Siewe DY, Xia Y | ACS nano | 20695478 | ACS Nano | 2010 Sep 28 |
Uniform beads with controllable pore sizes for biomedical applications. | Choi SW, Yeh YC, Zhang Y, Sung HW, Xia Y | Small (Weinheim an der Bergstrasse, Germany) | 20578116 | Small | 2010 Jul 19 |
Total synthesis of the polycyclic fungal metabolite (+/-)-communesin F. | Liu P, Seo JH, Weinreb SM | Angewandte Chemie (International ed. in English) | 20175174 | Angew Chem Int Ed Engl | 2010 Mar 8 |
Engineering the Properties of Metal Nanostructures via Galvanic Replacement Reactions. | Cobley CM, Xia Y | Materials science & engineering. R, Reports : a review journal | 21180400 | Mater Sci Eng R Rep | 2010 Nov 22 |
An enzyme-sensitive probe for photoacoustic imaging and fluorescence detection of protease activity. | Xia X, Yang M, Oetjen LK, Zhang Y, Li Q, Chen J, Xia Y | Nanoscale | 21225037 | Nanoscale | 2011 Mar |
Etching and dimerization: a simple and versatile route to dimers of silver nanospheres with a range of sizes. | Li W, Camargo PH, Au L, Zhang Q, Rycenga M, Xia Y | Angewandte Chemie (International ed. in English) | 19943304 | Angew Chem Int Ed Engl | 2010 |
Bright three-photon luminescence from gold/silver alloyed nanostructures for bioimaging with negligible photothermal toxicity. | Tong L, Cobley CM, Chen J, Xia Y, Cheng JX | Angewandte Chemie (International ed. in English) | 20544899 | Angew Chem Int Ed Engl | 2010 May 3 |
In vivo molecular photoacoustic tomography of melanomas targeted by bioconjugated gold nanocages. | Kim C, Cho EC, Chen J, Song KH, Au L, Favazza C, Zhang Q, Cobley CM, Gao F, Xia Y, Wang LV | ACS nano | 20731439 | ACS Nano | 2010 Aug 24 |
Fabrication of cubic nanocages and nanoframes by dealloying Au/Ag alloy nanoboxes with an aqueous etchant based on Fe(NO3)3 or NH4OH. | Lu X, Au L, McLellan J, Li ZY, Marquez M, Xia Y | Nano letters | 17489641 | Nano Lett | 2007 Jun |
Microscale polymer bottles corked with a phase-change material for temperature-controlled release. | Hyun DC, Lu P, Choi SI, Jeong U, Xia Y | Angewandte Chemie (International ed. in English) | 23959631 | Angew Chem Int Ed Engl | 2013 Sep 27 |
A Comparative Study of Galvanic Replacement Reactions Involving Ag Nanocubes and AuCl(2) or AuCl(4). | Au L, Lu X, Xia Y | Advanced materials (Deerfield Beach, Fla.) | 18725963 | Adv Mater | 2008 |
Fabrication of Density Gradients of Biodegradable Polymer Microparticles and Their Use in Guiding Neurite Outgrowth. | Li X, Macewan MR, Xie J Dr, Siewe D, Yuan X, Xia Y | Advanced functional materials | 21687818 | Adv Funct Mater | 2010 May 25 |
Probing the surface-enhanced Raman scattering properties of Au-Ag nanocages at two different excitation wavelengths. | Rycenga M, Hou KK, Cobley CM, Schwartz AG, Camargo PH, Xia Y | Physical chemistry chemical physics : PCCP | 19588011 | Phys Chem Chem Phys | 2009 Jul 28 |
Metal-polymer hybrid colloidal particles with an eccentric structure. | Ohnuma A, Cho EC, Jiang M, Ohtani B, Xia Y | Langmuir : the ACS journal of surfaces and colloids | 19621917 | Langmuir | 2009 Dec 15 |
A new theranostic system based on gold nanocages and phase-change materials with unique features for photoacoustic imaging and controlled release. | Moon GD, Choi SW, Cai X, Li W, Cho EC, Jeong U, Wang LV, Xia Y | Journal of the American Chemical Society | 21401092 | J Am Chem Soc | 2011 Apr 6 |
Synthesis of gold microplates using bovine serum albumin as a reductant and a stabilizer. | Au L, Lim B, Colletti P, Jun YS, Xia Y | Chemistry, an Asian journal | 19967737 | Chem Asian J | 2010 Jan 4 |
Putting Electrospun Nanofibers to Work for Biomedical Research. | Xie J, Li X, Xia Y | Macromolecular rapid communications | 20011452 | Macromol Rapid Commun | 2008 Nov 19 |
Synthesis and Optical Properties of Cubic Gold Nanoframes. | Au L, Chen Y, Zhou F, Camargo PH, Lim B, Li ZY, Ginger DS, Xia Y | Nano research | 20200595 | Nano Res | 2008 Dec 1 |
Stimuli-Responsive Materials for Controlled Release of Theranostic Agents. | Wang Y, Shim MS, Levinson NS, Sung HW, Xia Y | Advanced functional materials | 25477774 | Adv Funct Mater | 2014 Jul 16 |
Seeing Through the Surface: Non-invasive Characterization of Biomaterial-Tissue Interactions Using Photoacoustic Microscopy. | Zhang YS, Wang LV, Xia Y | Annals of biomedical engineering | 26471785 | Ann Biomed Eng | 2016 Mar |
Radiolabeling of Gold Nanocages for Potential Applications in Tracking, Diagnosis, and Image-Guided Therapy. | Qiu J, Liu Y, Xia Y | Advanced healthcare materials | 33470560 | Adv Healthc Mater | 2021 Aug |
Seed-mediated synthesis of truncated gold decahedrons with a AuCl/oleylamine complex as precursor. | Ma Y, Zeng J, Li W, McKiernan M, Xie Z, Xia Y | Advanced materials (Deerfield Beach, Fla.) | 20301132 | Adv Mater | 2010 May 4 |
Targeting gold nanocages to cancer cells for photothermal destruction and drug delivery. | Cobley CM, Au L, Chen J, Xia Y | Expert opinion on drug delivery | 20345327 | Expert Opin Drug Deliv | 2010 May |
Chitosan-Based Inverse Opals: Three-Dimensional Scaffolds with Uniform Pore Structures for Cell Culture. | Choi SW, Xie J, Xia Y | Advanced materials (Deerfield Beach, Fla.) | 19710950 | Adv Mater | 2009 Apr 15 |
The effects of size, shape, and surface functional group of gold nanostructures on their adsorption and internalization by cells. | Cho EC, Au L, Zhang Q, Xia Y | Small (Weinheim an der Bergstrasse, Germany) | 20029850 | Small | 2010 Feb 22 |
Nanofiber scaffolds with gradations in mineral content for mimicking the tendon-to-bone insertion site. | Li X, Xie J, Lipner J, Yuan X, Thomopoulos S, Xia Y | Nano letters | 19537737 | Nano Lett | 2009 Jul |
Gold nanocages as photothermal transducers for cancer treatment. | Chen J, Glaus C, Laforest R, Zhang Q, Yang M, Gidding M, Welch MJ, Xia Y | Small (Weinheim an der Bergstrasse, Germany) | 20225187 | Small | 2010 Apr 9 |
Neurite outgrowth on nanofiber scaffolds with different orders, structures, and surface properties. | Xie J, MacEwan MR, Li X, Sakiyama-Elbert SE, Xia Y | ACS nano | 19397333 | ACS Nano | 2009 May 26 |
Noninvasive photoacoustic microscopy of living cells in two and three dimensions through enhancement by a metabolite dye. | Zhang Y, Cai X, Wang Y, Zhang C, Li L, Choi SW, Wang LV, Xia Y | Angewandte Chemie (International ed. in English) | 21681876 | Angew Chem Int Ed Engl | 2011 Aug 1 |
Controlling the synthesis and assembly of silver nanostructures for plasmonic applications. | Rycenga M, Cobley CM, Zeng J, Li W, Moran CH, Zhang Q, Qin D, Xia Y | Chemical reviews | 21395318 | Chem Rev | 2011 Jun 8 |
Recent Developments in Shape-Controlled Synthesis of Silver Nanocrystals. | Xia X, Zeng J, Zhang Q, Moran CH, Xia Y | The journal of physical chemistry. C, Nanomaterials and interfaces | 23105955 | J Phys Chem C Nanomater Interfaces | 2012 |
Facile synthesis of Ag nanocubes and Au nanocages. | Skrabalak SE, Au L, Li X, Xia Y | Nature protocols | 17853874 | Nat Protoc | 2007 |
Facile synthesis of gold nanoparticles with narrow size distribution by using AuCl or AuBr as the precursor. | Lu X, Tuan HY, Korgel BA, Xia Y | Chemistry (Weinheim an der Bergstrasse, Germany) | 18058964 | Chemistry | 2008 |
Tailoring the Optical and Catalytic Properties of Gold-Silver Nanoboxes and Nanocages by Introducing Palladium. | Cobley CM, Campbell DJ, Xia Y | Advanced materials (Deerfield Beach, Fla.) | 18568091 | Adv Mater | 2008 Feb |
Isolating and probing the hot spot formed between two silver nanocubes. | Camargo PH, Rycenga M, Au L, Xia Y | Angewandte Chemie (International ed. in English) | 19199309 | Angew Chem Int Ed Engl | 2009 |
A reactive oxygen species (ROS)-responsive polymer for safe, efficient, and targeted gene delivery in cancer cells. | Shim MS, Xia Y | Angewandte Chemie (International ed. in English) | 23716349 | Angew Chem Int Ed Engl | 2013 Jul 1 |
Photoacoustic Microscopy in Tissue Engineering. | Cai X, Zhang YS, Xia Y, Wang LV | Materials today (Kidlington, England) | 23766667 | Mater Today (Kidlington) | 2013 Mar 1 |
Gold nanocages covered with thermally-responsive polymers for controlled release by high-intensity focused ultrasound. | Li W, Cai X, Kim C, Sun G, Zhang Y, Deng R, Yang M, Chen J, Achilefu S, Wang LV, Xia Y | Nanoscale | 21321760 | Nanoscale | 2011 Apr |
Modifying the pores of an inverse opal scaffold with chitosan microstructures for truly three-dimensional cell culture. | Zhang Y, Choi SW, Xia Y | Macromolecular rapid communications | 22231861 | Macromol Rapid Commun | 2012 Feb 27 |
Gold nanocages as contrast agents for photoacoustic imaging. | Li W, Brown PK, Wang LV, Xia Y | Contrast media & molecular imaging | 22025337 | Contrast Media Mol Imaging | 2011 Sep-Oct |
SV119-gold nanocage conjugates: a new platform for targeting cancer cells via sigma-2 receptors. | Wang Y, Xu J, Xia X, Yang M, Vangveravong S, Chen J, Mach RH, Xia Y | Nanoscale | 22113350 | Nanoscale | 2012 Jan 21 |
Generation of hot spots with silver nanocubes for single-molecule detection by surface-enhanced Raman scattering. | Rycenga M, Xia X, Moran CH, Zhou F, Qin D, Li ZY, Xia Y | Angewandte Chemie (International ed. in English) | 21542081 | Angew Chem Int Ed Engl | 2011 Jun 6 |
Vibrational response of Au-Ag nanoboxes and nanocages to ultrafast laser-induced heating. | Petrova H, Lin CH, Hu M, Chen J, Siekkinen AR, Xia Y, Sader JE, Hartland GV | Nano letters | 17358093 | Nano Lett | 2007 Apr |
Facile synthesis of branched au nanostructures by templating against a self-destructive lattice of magnetic fe nanoparticles. | Li Z, Li W, Camargo PH, Xia Y | Angewandte Chemie (International ed. in English) | 18988222 | Angew Chem Int Ed Engl | 2008 |
The differentiation of embryonic stem cells seeded on electrospun nanofibers into neural lineages. | Xie J, Willerth SM, Li X, Macewan MR, Rader A, Sakiyama-Elbert SE, Xia Y | Biomaterials | 18930315 | Biomaterials | 2009 Jan |
Measuring the SERS Enhancement Factors of Dimers with Different Structures Constructed from Silver Nanocubes. | Camargo PH, Au L, Rycenga M, Li W, Xia Y | Chemical physics letters | 20209069 | Chem Phys Lett | 2010 Jan |
Using SV119-gold nanocage conjugates to eradicate cancer stem cells through a combination of photothermal and chemo therapies. | Sun T, Wang Y, Wang Y, Xu J, Zhao X, Vangveravong S, Mach RH, Xia Y | Advanced healthcare materials | 24677807 | Adv Healthc Mater | 2014 Aug |
Silver nanocube on gold microplate as a well-defined and highly active substrate for SERS detection. | Xia X, Rycenga M, Qin D, Xia Y | Journal of materials chemistry. C | 24187611 | J Mater Chem C Mater | 2013 Oct 14 |
25th anniversary article: galvanic replacement: a simple and versatile route to hollow nanostructures with tunable and well-controlled properties. | Xia X, Wang Y, Ruditskiy A, Xia Y | Advanced materials (Deerfield Beach, Fla.) | 24027074 | Adv Mater | 2013 Nov 26 |
A Facile and General Method for the Encapsulation of Different Types of Imaging Contrast Agents Within Micrometer-Sized Polymer Beads. | Bai MY, Moran CH, Zhang L, Liu C, Zhang Y, Wang LV, Xia Y | Advanced functional materials | 31866803 | Adv Funct Mater | 2012 Feb 22 |
Silica-coated dimers of silver nanospheres as surface-enhanced Raman scattering tags for imaging cancer cells. | Xia X, Li W, Zhang Y, Xia Y | Interface focus | 24427538 | Interface Focus | 2013 Jun 6 |
Putting gold nanocages to work for optical imaging, controlled release and cancer theranostics. | Pang B, Yang X, Xia Y | Nanomedicine (London, England) | 27348546 | Nanomedicine (Lond) | 2016 Jul |
Volume exclusion and soft interaction effects on protein stability under crowded conditions. | Miklos AC, Li C, Sharaf NG, Pielak GJ | Biochemistry | 20672856 | Biochemistry | 2010 Aug 24 |
Protein nuclear magnetic resonance under physiological conditions. | Pielak GJ, Li C, Miklos AC, Schlesinger AP, Slade KM, Wang GF, Zigoneanu IG | Biochemistry | 19113834 | Biochemistry | 2009 Jan 20 |
Protein (19)F NMR in Escherichia coli. | Li C, Wang GF, Wang Y, Creager-Allen R, Lutz EA, Scronce H, Slade KM, Ruf RA, Mehl RA, Pielak GJ | Journal of the American Chemical Society | 20050707 | J Am Chem Soc | 2010 Jan 13 |
Disordered Protein Diffusion under Crowded Conditions. | Wang Y, Benton LA, Singh V, Pielak GJ | The journal of physical chemistry letters | 23185649 | J Phys Chem Lett | 2012 Sep 20 |
Residue-level interrogation of macromolecular crowding effects on protein stability. | Charlton LM, Barnes CO, Li C, Orans J, Young GB, Pielak GJ | Journal of the American Chemical Society | 18459780 | J Am Chem Soc | 2008 May 28 |
19F NMR studies of alpha-synuclein conformation and fibrillation. | Li C, Lutz EA, Slade KM, Ruf RA, Wang GF, Pielak GJ | Biochemistry | 19655784 | Biochemistry | 2009 Sep 15 |
Quantifying green fluorescent protein diffusion in Escherichia coli by using continuous photobleaching with evanescent illumination. | Slade KM, Steele BL, Pielak GJ, Thompson NL | The journal of physical chemistry. B | 19296673 | J Phys Chem B | 2009 Apr 9 |
Macromolecular crowding fails to fold a globular protein in cells. | Schlesinger AP, Wang Y, Tadeo X, Millet O, Pielak GJ | Journal of the American Chemical Society | 21534566 | J Am Chem Soc | 2011 Jun 1 |
Interaction of α-synuclein and a cell penetrating fusion peptide with higher eukaryotic cell membranes assessed by ¹⁹F NMR. | Zigoneanu IG, Pielak GJ | Molecular pharmaceutics | 22376087 | Mol Pharm | 2012 Apr 2 |
In situ structural characterization of a recombinant protein in native Escherichia coli membranes with solid-state magic-angle-spinning NMR. | Fu R, Wang X, Li C, Santiago-Miranda AN, Pielak GJ, Tian F | Journal of the American Chemical Society | 21774553 | J Am Chem Soc | 2011 Aug 17 |
Alpha-Synuclein conformation affects its tyrosine-dependent oxidative aggregation. | Ruf RA, Lutz EA, Zigoneanu IG, Pielak GJ | Biochemistry | 19049426 | Biochemistry | 2008 Dec 23 |
Using NMR to distinguish viscosity effects from nonspecific protein binding under crowded conditions. | Li C, Pielak GJ | Journal of the American Chemical Society | 19140727 | J Am Chem Soc | 2009 Feb 4 |
Effects of proteins on protein diffusion. | Wang Y, Li C, Pielak GJ | Journal of the American Chemical Society | 20560582 | J Am Chem Soc | 2010 Jul 14 |
Probing the micelle-bound aggregation-prone state of α-synuclein with (19)F NMR spectroscopy. | Wang GF, Li C, Pielak GJ | Chembiochem : a European journal of chemical biology | 20730847 | Chembiochem | 2010 Sep 24 |
A bioreactor for in-cell protein NMR. | Sharaf NG, Barnes CO, Charlton LM, Young GB, Pielak GJ | Journal of magnetic resonance (San Diego, Calif. : 1997) | 19910228 | J Magn Reson | 2010 Feb |
Differential dynamical effects of macromolecular crowding on an intrinsically disordered protein and a globular protein: implications for in-cell NMR spectroscopy. | Li C, Charlton LM, Lakkavaram A, Seagle C, Wang G, Young GB, Macdonald JM, Pielak GJ | Journal of the American Chemical Society | 18419123 | J Am Chem Soc | 2008 May 21 |
Interaction of α-synuclein with vesicles that mimic mitochondrial membranes. | Zigoneanu IG, Yang YJ, Krois AS, Haque E, Pielak GJ | Biochimica et biophysica acta | 22155643 | Biochim Biophys Acta | 2012 Mar |
Translational and rotational diffusion of a small globular protein under crowded conditions. | Li C, Wang Y, Pielak GJ | The journal of physical chemistry. B | 19791823 | J Phys Chem B | 2009 Oct 8 |
Effects of recombinant protein expression on green fluorescent protein diffusion in Escherichia coli. | Slade KM, Baker R, Chua M, Thompson NL, Pielak GJ | Biochemistry | 19413350 | Biochemistry | 2009 Jun 16 |
In-cell protein NMR and protein leakage. | Barnes CO, Pielak GJ | Proteins | 21120863 | Proteins | 2011 Feb |
Development of antibody surrogates for the treatment of cancers and autoimmune disease. | Kodadek T | Current opinion in chemical biology | 20674470 | Curr Opin Chem Biol | 2010 Dec |
Seamless bead to microarray screening: rapid identification of the highest affinity protein ligands from large combinatorial libraries. | Astle JM, Simpson LS, Huang Y, Reddy MM, Wilson R, Connell S, Wilson J, Kodadek T | Chemistry & biology | 20142039 | Chem Biol | 2010 Jan 29 |
Potent and selective photo-inactivation of proteins with peptoid-ruthenium conjugates. | Lee J, Udugamasooriya DG, Lim HS, Kodadek T | Nature chemical biology | 20228793 | Nat Chem Biol | 2010 Apr |
Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation. | Cai D, Shames DS, Raso MG, Xie Y, Kim YH, Pollack JR, Girard L, Sullivan JP, Gao B, Peyton M, Nanjundan M, Byers L, Heymach J, Mills G, Gazdar AF, Wistuba I, Kodadek T, Minna JD | Cancer research | 20663904 | Cancer Res | 2010 Aug 15 |
The pharmacophore of a peptoid VEGF receptor 2 antagonist includes both side chain and main chain residues. | Udugamasooriya DG, Dunham G, Ritchie C, Brekken RA, Kodadek T | Bioorganic & medicinal chemistry letters | 18653335 | Bioorg Med Chem Lett | 2008 Nov 15 |
Selective toxin sequestrants for the treatment of bacterial infections. | Simpson LS, Burdine L, Dutta AK, Feranchak AP, Kodadek T | Journal of the American Chemical Society | 19351156 | J Am Chem Soc | 2009 Apr 29 |
Identification of candidate IgG biomarkers for Alzheimer's disease via combinatorial library screening. | Reddy MM, Wilson R, Wilson J, Connell S, Gocke A, Hynan L, German D, Kodadek T | Cell | 21215375 | Cell | 2011 Jan 7 |
High-throughput evaluation of relative cell permeability between peptoids and peptides. | Tan NC, Yu P, Kwon YU, Kodadek T | Bioorganic & medicinal chemistry | 18490170 | Bioorg Med Chem | 2008 Jun 1 |
Isolation of antagonists of antigen-specific autoimmune T cell proliferation. | Gocke AR, Udugamasooriya DG, Archer CT, Lee J, Kodadek T | Chemistry & biology | 19942136 | Chem Biol | 2009 Nov 25 |
Periodate-triggered cross-linking reveals Sug2/Rpt4 as the molecular target of a peptoid inhibitor of the 19S proteasome regulatory particle. | Lim HS, Cai D, Archer CT, Kodadek T | Journal of the American Chemical Society | 17929816 | J Am Chem Soc | 2007 Oct 31 |
Identification of a peptoid inhibitor of the proteasome 19S regulatory particle. | Lim HS, Archer CT, Kodadek T | Journal of the American Chemical Society | 17536803 | J Am Chem Soc | 2007 Jun 27 |
Synthetic receptors with antibody-like binding affinities. | Kodadek T | Current opinion in chemical biology | 20674471 | Curr Opin Chem Biol | 2010 Dec |
Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells. | Hartigan-O'Connor DJ, Poon C, Sinclair E, McCune JM | Journal of immunological methods | 17173927 | J Immunol Methods | 2007 Jan 30 |
Preclinical evaluation of HIV eradication strategies in the simian immunodeficiency virus-infected rhesus macaque: a pilot study testing inhibition of indoleamine 2,3-dioxygenase. | Dunham RM, Gordon SN, Vaccari M, Piatak M, Huang Y, Deeks SG, Lifson J, Franchini G, McCune JM | AIDS research and human retroviruses | 22924680 | AIDS Res Hum Retroviruses | 2013 Feb |
SIV replication in the infected rhesus macaque is limited by the size of the preexisting TH17 cell compartment. | Hartigan-O'Connor DJ, Abel K, Van Rompay KK, Kanwar B, McCune JM | Science translational medicine | 22649090 | Sci Transl Med | 2012 May 30 |
Upregulation of retinal dehydrogenase 2 in alternatively activated macrophages during retinoid-dependent type-2 immunity to helminth infection in mice. | Broadhurst MJ, Leung JM, Lim KC, Girgis NM, Gundra UM, Fallon PG, Premenko-Lanier M, McKerrow JH, McCune JM, Loke P | PLoS pathogens | 22927819 | PLoS Pathog | 2012 |
IL-22+ CD4+ T cells are associated with therapeutic trichuris trichiura infection in an ulcerative colitis patient. | Broadhurst MJ, Leung JM, Kashyap V, McCune JM, Mahadevan U, McKerrow JH, Loke P | Science translational medicine | 21123809 | Sci Transl Med | 2010 Dec 1 |
The role of transplacental microtransfusions of maternal lymphocytes in in utero HIV transmission. | Lee TH, Chafets DM, Biggar RJ, McCune JM, Busch MP | Journal of acquired immune deficiency syndromes (1999) | 20683195 | J Acquir Immune Defic Syndr | 2010 Oct |
Breaking free of sample size dogma to perform innovative translational research. | Bacchetti P, Deeks SG, McCune JM | Science translational medicine | 21677197 | Sci Transl Med | 2011 Jun 15 |
Fetal and adult hematopoietic stem cells give rise to distinct T cell lineages in humans. | Mold JE, Venkatasubrahmanyam S, Burt TD, Michaëlsson J, Rivera JM, Galkina SA, Weinberg K, Stoddart CA, McCune JM | Science (New York, N.Y.) | 21164017 | Science | 2010 Dec 17 |
HIV-specific CD4+ T cells may contribute to viral persistence in HIV controllers. | Hunt PW, Hatano H, Sinclair E, Lee TH, Busch MP, Martin JN, McCune JM, Deeks SG | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | 21245154 | Clin Infect Dis | 2011 Mar 1 |
IFN-alpha-induced upregulation of CCR5 leads to expanded HIV tropism in vivo. | Stoddart CA, Keir ME, McCune JM | PLoS pathogens | 20174557 | PLoS Pathog | 2010 Feb 19 |
Cytomegalovirus-specific T cells persist at very high levels during long-term antiretroviral treatment of HIV disease. | Naeger DM, Martin JN, Sinclair E, Hunt PW, Bangsberg DR, Hecht F, Hsue P, McCune JM, Deeks SG | PloS one | 20126452 | PLoS One | 2010 Jan 29 |
IL-2 production correlates with effector cell differentiation in HIV-specific CD8+ T cells. | Nomura LE, Emu B, Hoh R, Haaland P, Deeks SG, Martin JN, McCune JM, Nixon DF, Maecker HT | AIDS research and therapy | 16859558 | AIDS Res Ther | 2006 Jul 21 |
Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero. | Mold JE, Michaëlsson J, Burt TD, Muench MO, Beckerman KP, Busch MP, Lee TH, Nixon DF, McCune JM | Science (New York, N.Y.) | 19056990 | Science | 2008 Dec 5 |
Levels of circulating myeloid subpopulations and of heme oxygenase-1 do not predict CD4(+) T cell recovery after the initiation of antiretroviral therapy for HIV disease. | Seu L, Ortiz GM, Burt TD, Deeks SG, Martin JN, McCune JM | AIDS research and therapy | 25180041 | AIDS Res Ther | 2014 |
Suppression of SIV-specific CD4+ T cells by infant but not adult macaque regulatory T cells: implications for SIV disease progression. | Hartigan-O'Connor DJ, Abel K, McCune JM | The Journal of experimental medicine | 17954571 | J Exp Med | 2007 Oct 29 |
In vivo imaging of mucosal CD4+ T cells using single photon emission computed tomography in a murine model of colitis. | Kanwar B, Gao DW, Hwang AB, Grenert JP, Williams SP, Franc B, McCune JM | Journal of immunological methods | 17964595 | J Immunol Methods | 2008 Jan 1 |
Evidence for persistent low-level viremia in individuals who control human immunodeficiency virus in the absence of antiretroviral therapy. | Hatano H, Delwart EL, Norris PJ, Lee TH, Dunn-Williams J, Hunt PW, Hoh R, Stramer SL, Linnen JM, McCune JM, Martin JN, Busch MP, Deeks SG | Journal of virology | 18945778 | J Virol | 2009 Jan |
Antiviral antibodies are necessary for control of simian immunodeficiency virus replication. | Miller CJ, Genescà M, Abel K, Montefiori D, Forthal D, Bost K, Li J, Favre D, McCune JM | Journal of virology | 17329327 | J Virol | 2007 May |
HIV-induced changes in T cell signaling pathways. | Schweneker M, Favre D, Martin JN, Deeks SG, McCune JM | Journal of immunology (Baltimore, Md. : 1950) | 18453567 | J Immunol | 2008 May 15 |
Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy. | Hunt PW, Brenchley J, Sinclair E, McCune JM, Roland M, Page-Shafer K, Hsue P, Emu B, Krone M, Lampiris H, Douek D, Martin JN, Deeks SG | The Journal of infectious diseases | 18171295 | J Infect Dis | 2008 Jan 1 |
Single-Cell Mapping of Progressive Fetal-to-Adult Transition in Human Naive T Cells. | Bunis DG, Bronevetsky Y, Krow-Lucal E, Bhakta NR, Kim CC, Nerella S, Jones N, Mendoza VF, Bryson YJ, Gern JE, Rutishauser RL, Ye CJ, Sirota M, McCune JM, Burt TD | Cell reports | 33406429 | Cell Rep | 2021 Jan 5 |
Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease. | Favre D, Mold J, Hunt PW, Kanwar B, Loke P, Seu L, Barbour JD, Lowe MM, Jayawardene A, Aweeka F, Huang Y, Douek DC, Brenchley JM, Martin JN, Hecht FM, Deeks SG, McCune JM | Science translational medicine | 20484731 | Sci Transl Med | 2010 May 19 |
Expression of the autoimmune susceptibility gene FcRL3 on human regulatory T cells is associated with dysfunction and high levels of programmed cell death-1. | Swainson LA, Mold JE, Bajpai UD, McCune JM | Journal of immunology (Baltimore, Md. : 1950) | 20190142 | J Immunol | 2010 Apr 1 |
Cell-based measures of viral persistence are associated with immune activation and programmed cell death protein 1 (PD-1)-expressing CD4+ T cells. | Hatano H, Jain V, Hunt PW, Lee TH, Sinclair E, Do TD, Hoh R, Martin JN, McCune JM, Hecht F, Busch MP, Deeks SG | The Journal of infectious diseases | 23089590 | J Infect Dis | 2013 Jul |
A role for cytomegalovirus-specific CD4+CX3CR1+ T cells and cytomegalovirus-induced T-cell immunopathology in HIV-associated atherosclerosis. | Sacre K, Hunt PW, Hsue PY, Maidji E, Martin JN, Deeks SG, Autran B, McCune JM | AIDS (London, England) | 22313962 | AIDS | 2012 Apr 24 |
Hematopoietic-stem-cell-based gene therapy for HIV disease. | Kiem HP, Jerome KR, Deeks SG, McCune JM | Cell stem cell | 22305563 | Cell Stem Cell | 2012 Feb 3 |
Suberoylanilide hydroxamic acid reactivates HIV from latently infected cells. | Contreras X, Schweneker M, Chen CS, McCune JM, Deeks SG, Martin J, Peterlin BM | The Journal of biological chemistry | 19136668 | J Biol Chem | 2009 Mar 13 |
Gag p27-specific B- and T-cell responses in Simian immunodeficiency virus SIVagm-infected African green monkeys. | Lozano Reina JM, Favre D, Kasakow Z, Mayau V, Nugeyre MT, Ka T, Faye A, Miller CJ, Scott-Algara D, McCune JM, Barré-Sinoussi F, Diop OM, Müller-Trutwin MC | Journal of virology | 19109377 | J Virol | 2009 Mar |
Variations in the heme oxygenase-1 microsatellite polymorphism are associated with plasma CD14 and viral load in HIV-infected African-Americans. | Seu L, Burt TD, Witte JS, Martin JN, Deeks SG, McCune JM | Genes and immunity | 22048453 | Genes Immun | 2012 Apr |
IL-7 production in murine lymphatic endothelial cells and induction in the setting of peripheral lymphopenia. | Miller CN, Hartigan-O'Connor DJ, Lee MS, Laidlaw G, Cornelissen IP, Matloubian M, Coughlin SR, McDonald DM, McCune JM | International immunology | 23657000 | Int Immunol | 2013 Aug |
Analysis of maternal microchimerism in rhesus monkeys (Macaca mulatta) using real-time quantitative PCR amplification of MHC polymorphisms. | Bakkour S, Baker CA, Tarantal AF, Wen L, Busch MP, Lee TH, McCune JM | Chimerism | 24451553 | Chimerism | 2014 Jan-Mar |
Dysbiosis of the gut microbiota is associated with HIV disease progression and tryptophan catabolism. | Vujkovic-Cvijin I, Dunham RM, Iwai S, Maher MC, Albright RG, Broadhurst MJ, Hernandez RD, Lederman MM, Huang Y, Somsouk M, Deeks SG, Hunt PW, Lynch SV, McCune JM | Science translational medicine | 23843452 | Sci Transl Med | 2013 Jul 10 |
Continuous Antigenic Stimulation of DO11.10 TCR Transgenic Mice in the Presence or Absence of IL-1β: Possible Implications for Mechanisms of T Cell Depletion in HIV Disease. | Ladell K, Hazenberg MD, Fitch M, Emson C, McEvoy-Hein Asgarian BK, Mold JE, Miller C, Busch R, Price DA, Hellerstein MK, McCune JM | Journal of immunology (Baltimore, Md. : 1950) | 26416271 | J Immunol | 2015 Nov 1 |
Composition and function of T cell subpopulations are slow to change despite effective antiretroviral treatment of HIV disease. | Emu B, Moretto WJ, Hoh R, Krone M, Martin JN, Nixon DF, Deeks SG, McCune JM | PloS one | 24465619 | PLoS One | 2014 |
Identification of cinnabarinic acid as a novel endogenous aryl hydrocarbon receptor ligand that drives IL-22 production. | Lowe MM, Mold JE, Kanwar B, Huang Y, Louie A, Pollastri MP, Wang C, Patel G, Franks DG, Schlezinger J, Sherr DH, Silverstone AE, Hahn ME, McCune JM | PloS one | 24498387 | PLoS One | 2014 |
Therapeutic helminth infection of macaques with idiopathic chronic diarrhea alters the inflammatory signature and mucosal microbiota of the colon. | Broadhurst MJ, Ardeshir A, Kanwar B, Mirpuri J, Gundra UM, Leung JM, Wiens KE, Vujkovic-Cvijin I, Kim CC, Yarovinsky F, Lerche NW, McCune JM, Loke P | PLoS pathogens | 23166490 | PLoS Pathog | 2012 |
Prevalence of CXCR4 tropism among antiretroviral-treated HIV-1-infected patients with detectable viremia. | Hunt PW, Harrigan PR, Huang W, Bates M, Williamson DW, McCune JM, Price RW, Spudich SS, Lampiris H, Hoh R, Leigler T, Martin JN, Deeks SG | The Journal of infectious diseases | 16960780 | J Infect Dis | 2006 Oct 1 |
Increased circulating interleukin-7 levels in HIV-1-infected women. | Napolitano LA, Burt TD, Bacchetti P, Barrón Y, French AL, Kovacs A, Anastos K, Young M, McCune JM, Greenblatt RM | Journal of acquired immune deficiency syndromes (1999) | 16284535 | J Acquir Immune Defic Syndr | 2005 Dec 15 |
Naive human T cells are activated and proliferate in response to the heme oxygenase-1 inhibitor tin mesoporphyrin. | Burt TD, Seu L, Mold JE, Kappas A, McCune JM | Journal of immunology (Baltimore, Md. : 1950) | 20921523 | J Immunol | 2010 Nov 1 |
Persistent systemic inflammation and atypical enterocolitis in patients with NEMO syndrome. | Cheng LE, Kanwar B, Tcheurekdjian H, Grenert JP, Muskat M, Heyman MB, McCune JM, Wara DW | Clinical immunology (Orlando, Fla.) | 19375390 | Clin Immunol | 2009 Jul |
Central memory CD8+ T cells appear to have a shorter lifespan and reduced abundance as a function of HIV disease progression. | Ladell K, Hellerstein MK, Cesar D, Busch R, Boban D, McCune JM | Journal of immunology (Baltimore, Md. : 1950) | 18523254 | J Immunol | 2008 Jun 15 |
Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection. | Jones RB, Ndhlovu LC, Barbour JD, Sheth PM, Jha AR, Long BR, Wong JC, Satkunarajah M, Schweneker M, Chapman JM, Gyenes G, Vali B, Hyrcza MD, Yue FY, Kovacs C, Sassi A, Loutfy M, Halpenny R, Persad D, Spotts G, Hecht FM, Chun TW, McCune JM, Kaul R, Rini JM, Nixon DF, Ostrowski MA | The Journal of experimental medicine | 19001139 | J Exp Med | 2008 Nov 24 |
Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection. | Favre D, Lederer S, Kanwar B, Ma ZM, Proll S, Kasakow Z, Mold J, Swainson L, Barbour JD, Baskin CR, Palermo R, Pandrea I, Miller CJ, Katze MG, McCune JM | PLoS pathogens | 19214220 | PLoS Pathog | 2009 Feb |
A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers. | Hunt PW, Landay AL, Sinclair E, Martinson JA, Hatano H, Emu B, Norris PJ, Busch MP, Martin JN, Brooks C, McCune JM, Deeks SG | PloS one | 21305005 | PLoS One | 2011 Jan 31 |
HIV disease progression correlates with the generation of dysfunctional naive CD8(low) T cells. | Favre D, Stoddart CA, Emu B, Hoh R, Martin JN, Hecht FM, Deeks SG, McCune JM | Blood | 21200021 | Blood | 2011 Feb 17 |
A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell response. | Hatano H, Hayes TL, Dahl V, Sinclair E, Lee TH, Hoh R, Lampiris H, Hunt PW, Palmer S, McCune JM, Martin JN, Busch MP, Shacklett BL, Deeks SG | The Journal of infectious diseases | 21402547 | J Infect Dis | 2011 Apr 1 |
Higher CD27+CD8+ T cells percentages during suppressive antiretroviral therapy predict greater subsequent CD4+ T cell recovery in treated HIV infection. | Seu L, Ortiz GM, Epling L, Sinclair E, Swainson LA, Bajpai UD, Huang Y, Deeks SG, Hunt PW, Martin JN, McCune JM | PloS one | 24391889 | PLoS One | 2013 |
Hydroxychloroquine is associated with impaired interferon-alpha and tumor necrosis factor-alpha production by plasmacytoid dendritic cells in systemic lupus erythematosus. | Sacre K, Criswell LA, McCune JM | Arthritis research & therapy | 22734582 | Arthritis Res Ther | 2012 Jun 27 |
Growth hormone enhances thymic function in HIV-1-infected adults. | Napolitano LA, Schmidt D, Gotway MB, Ameli N, Filbert EL, Ng MM, Clor JL, Epling L, Sinclair E, Baum PD, Li K, Killian ML, Bacchetti P, McCune JM | The Journal of clinical investigation | 18292808 | J Clin Invest | 2008 Mar |
Rooted in risk: genetic predisposition for low-density lipoprotein cholesterol level associates with diminished low-density lipoprotein cholesterol response to statin treatment. | Smit RA, Postmus I, Trompet S, Barnes MR, Warren H, Arsenault BJ, Chasman DI, Cupples LA, Hitman GA, Krauss RM, Li X, Psaty BM, Stein CM, Rotter JI, Jukema JW | Pharmacogenomics | 27648687 | Pharmacogenomics | 2016 Oct |
CD57(+) Memory T Cells Proliferate In Vivo. | Ahmed R, Miners KL, Lahoz-Beneytez J, Jones RE, Roger L, Baboonian C, Zhang Y, Wang ECY, Hellerstein MK, McCune JM, Baird DM, Price DA, Macallan DC, Asquith B, Ladell K | Cell reports | 33326780 | Cell Rep | 2020 Dec 15 |
Regulation of T cell responses in the developing human fetus. | Michaëlsson J, Mold JE, McCune JM, Nixon DF | Journal of immunology (Baltimore, Md. : 1950) | 16670279 | J Immunol | 2006 May 15 |
Direct measurement of T-cell receptor repertoire diversity with AmpliCot. | Baum PD, McCune JM | Nature methods | 17060913 | Nat Methods | 2006 Nov |
Loss of T cell responses following long-term cryopreservation. | Owen RE, Sinclair E, Emu B, Heitman JW, Hirschkorn DF, Epling CL, Tan QX, Custer B, Harris JM, Jacobson MA, McCune JM, Martin JN, Hecht FM, Deeks SG, Norris PJ | Journal of immunological methods | 17707394 | J Immunol Methods | 2007 Sep 30 |
Design, construction, and validation of a modular library of sequence diversity standards for polymerase chain reaction. | Baum PD, Young JJ, Zhang Q, Kasakow Z, McCune JM | Analytical biochemistry | 21111699 | Anal Biochem | 2011 Apr 1 |
Measurement of absolute T cell receptor rearrangement diversity. | Baum PD, Young JJ, McCune JM | Journal of immunological methods | 21385585 | J Immunol Methods | 2011 May 31 |
Abacavir increases platelet reactivity via competitive inhibition of soluble guanylyl cyclase. | Baum PD, Sullam PM, Stoddart CA, McCune JM | AIDS (London, England) | 21941165 | AIDS | 2011 Nov 28 |
Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation. | Red-Horse K, Rivera J, Schanz A, Zhou Y, Winn V, Kapidzic M, Maltepe E, Okazaki K, Kochman R, Vo KC, Giudice L, Erlebacher A, McCune JM, Stoddart CA, Fisher SJ | The Journal of clinical investigation | 16998586 | J Clin Invest | 2006 Oct |
Increased carotid intima-media thickness in HIV patients is associated with increased cytomegalovirus-specific T-cell responses. | Hsue PY, Hunt PW, Sinclair E, Bredt B, Franklin A, Killian M, Hoh R, Martin JN, McCune JM, Waters DD, Deeks SG | AIDS (London, England) | 17117013 | AIDS | 2006 Nov 28 |
Immune activation, CD4+ T cell counts, and viremia exhibit oscillatory patterns over time in patients with highly resistant HIV infection. | Kitchen CM, Yeghiazarian L, Hoh R, McCune JM, Sinclair E, Martin JN, Deeks SG | PloS one | 21701594 | PLoS One | 2011 |
Exposure to SIV in utero results in reduced viral loads and altered responsiveness to postnatal challenge. | Baker CA, Swainson L, Lin DL, Wong S, Hartigan-O'Connor DJ, Lifson JD, Tarantal AF, McCune JM | Science translational medicine | 26268312 | Sci Transl Med | 2015 Aug 12 |
Transcriptional profiling in pathogenic and non-pathogenic SIV infections reveals significant distinctions in kinetics and tissue compartmentalization. | Lederer S, Favre D, Walters KA, Proll S, Kanwar B, Kasakow Z, Baskin CR, Palermo R, McCune JM, Katze MG | PLoS pathogens | 19214219 | PLoS Pathog | 2009 Feb |
Blood T-cell receptor diversity decreases during the course of HIV infection, but the potential for a diverse repertoire persists. | Baum PD, Young JJ, Schmidt D, Zhang Q, Hoh R, Busch M, Martin J, Deeks S, McCune JM | Blood | 22371879 | Blood | 2012 Apr 12 |
A functional variant in FCRL3 is associated with higher Fc receptor-like 3 expression on T cell subsets and rheumatoid arthritis disease activity. | Bajpai UD, Swainson LA, Mold JE, Graf JD, Imboden JB, McCune JM | Arthritis and rheumatism | 22392608 | Arthritis Rheum | 2012 Aug |
Correlating cellular and molecular signatures of mucosal immunity that distinguish HIV controllers from noncontrollers. | Loke P, Favre D, Hunt PW, Leung JM, Kanwar B, Martin JN, Deeks SG, McCune JM | Blood | 20160163 | Blood | 2010 Apr 15 |
Cellular response of polyvalent oligonucleotide-gold nanoparticle conjugates. | Massich MD, Giljohann DA, Schmucker AL, Patel PC, Mirkin CA | ACS nano | 20860397 | ACS Nano | 2010 Oct 26 |
Core-shell triangular bifrustums. | Yoo H, Millstone JE, Li S, Jang JW, Wei W, Wu J, Schatz GC, Mirkin CA | Nano letters | 19603815 | Nano Lett | 2009 Aug |
Nano-flares for mRNA regulation and detection. | Prigodich AE, Seferos DS, Massich MD, Giljohann DA, Lane BC, Mirkin CA | ACS nano | 19702321 | ACS Nano | 2009 Aug 25 |
Gene regulation with polyvalent siRNA-nanoparticle conjugates. | Giljohann DA, Seferos DS, Prigodich AE, Patel PC, Mirkin CA | Journal of the American Chemical Society | 19170493 | J Am Chem Soc | 2009 Feb 18 |
Tröger's-base-derived infinite co-ordination polymer microparticles. | Jeon YM, Armatas GS, Kim D, Kanatzidis MG, Mirkin CA | Small (Weinheim an der Bergstrasse, Germany) | 19058289 | Small | 2009 Jan |
Redox-activating dip-pen nanolithography (RA-DPN). | Braunschweig AB, Senesi AJ, Mirkin CA | Journal of the American Chemical Society | 19128060 | J Am Chem Soc | 2009 Jan 28 |
Topographically flat, chemically patterned PDMS stamps made by dip-pen nanolithography. | Zheng Z, Jang JW, Zheng G, Mirkin CA | Angewandte Chemie (International ed. in English) | 19012308 | Angew Chem Int Ed Engl | 2008 |
Nonenzymatic detection of bacterial genomic DNA using the bio bar code assay. | Hill HD, Vega RA, Mirkin CA | Analytical chemistry | 17927207 | Anal Chem | 2007 Dec 1 |
An Electrochemical Approach to and the Physical Consequences of Preparing Nanostructures from Gold Nanorods with Smooth Ends. | Banholzer MJ, Li S, Ketter JB, Rozkiewicz DI, Schatz GC, Mirkin CA | The journal of physical chemistry. C, Nanomaterials and interfaces | 22180788 | J Phys Chem C Nanomater Interfaces | 2008 Oct 9 |
Polyethylene glycol as a novel resist and sacrificial material for generating positive and negative nanostructures. | Sanedrin RG, Huang L, Jang JW, Kakkassery J, Mirkin CA | Small (Weinheim an der Bergstrasse, Germany) | 18563746 | Small | 2008 Jul |
Controlling the lattice parameters of gold nanoparticle FCC crystals with duplex DNA linkers. | Hill HD, Macfarlane RJ, Senesi AJ, Lee B, Park SY, Mirkin CA | Nano letters | 18572967 | Nano Lett | 2008 Aug |
Nanodisk codes. | Qin L, Banholzer MJ, Millstone JE, Mirkin CA | Nano letters | 18041858 | Nano Lett | 2007 Dec |
Iodide ions control seed-mediated growth of anisotropic gold nanoparticles. | Millstone JE, Wei W, Jones MR, Yoo H, Mirkin CA | Nano letters | 18642955 | Nano Lett | 2008 Aug |
Surface plasmon-mediated energy transfer in heterogap Au-Ag nanowires. | Wei W, Li S, Qin L, Xue C, Millstone JE, Xu X, Schatz GC, Mirkin CA | Nano letters | 18767888 | Nano Lett | 2008 Oct |
Microarray detection of duplex and triplex DNA binders with DNA-modified gold nanoparticles. | Lytton-Jean AK, Han MS, Mirkin CA | Analytical chemistry | 17614366 | Anal Chem | 2007 Aug 1 |
On-wire lithography-generated molecule-based transport junctions: a new testbed for molecular electronics. | Chen X, Jeon YM, Jang JW, Qin L, Huo F, Wei W, Mirkin CA | Journal of the American Chemical Society | 18528994 | J Am Chem Soc | 2008 Jul 2 |
Inversion of product selectivity in an enzyme-inspired metallosupramolecular tweezer catalyzed epoxidation reaction. | Ulmann PA, Braunschweig AB, Lee OS, Wiester MJ, Schatz GC, Mirkin CA | Chemical communications (Cambridge, England) | 20448966 | Chem Commun (Camb) | 2009 Sep 14 |
Surprisingly long-range surface-enhanced Raman scattering (SERS) on Au-Ni multisegmented nanowires. | Wei W, Li S, Millstone JE, Banholzer MJ, Chen X, Xu X, Schatz GC, Mirkin CA | Angewandte Chemie (International ed. in English) | 19431164 | Angew Chem Int Ed Engl | 2009 |
Plasmonic focusing in rod-sheath heteronanostructures. | Chen X, Li S, Xue C, Banholzer MJ, Schatz GC, Mirkin CA | ACS nano | 19206253 | ACS Nano | 2009 Jan 27 |
Reversible Ligand Pairing and Sorting Processes Leading to Heteroligated Palladium(II) Complexes with Hemilabile Ligands. | Ulmann PA, Mirkin CA, DiPasquale AG, Liable-Sands LM, Rheingold AL | Organometallics | 34446977 | Organometallics | 2009 Feb 23 |
Gold nanoparticles for biology and medicine. | Giljohann DA, Seferos DS, Daniel WL, Massich MD, Patel PC, Mirkin CA | Angewandte Chemie (International ed. in English) | 20401880 | Angew Chem Int Ed Engl | 2010 Apr 26 |
Templated spherical high density lipoprotein nanoparticles. | Thaxton CS, Daniel WL, Giljohann DA, Thomas AD, Mirkin CA | Journal of the American Chemical Society | 19133723 | J Am Chem Soc | 2009 Feb 4 |
The role radius of curvature plays in thiolated oligonucleotide loading on gold nanoparticles. | Hill HD, Millstone JE, Banholzer MJ, Mirkin CA | ACS nano | 19236080 | ACS Nano | 2009 Feb 24 |
PCR-like cascade reactions in the context of an allosteric enzyme mimic. | Yoon HJ, Mirkin CA | Journal of the American Chemical Society | 18681433 | J Am Chem Soc | 2008 Sep 3 |
A self-correcting inking strategy for cantilever arrays addressed by an inkjet printer and used for dip-pen nanolithography. | Wang Y, Giam LR, Park M, Lenhert S, Fuchs H, Mirkin CA | Small (Weinheim an der Bergstrasse, Germany) | 18654990 | Small | 2008 Oct |
Multipole plasmon resonances in gold nanorods. | Payne EK, Shuford KL, Park S, Schatz GC, Mirkin CA | The journal of physical chemistry. B | 16471797 | J Phys Chem B | 2006 Feb 9 |
Aptamer nano-flares for molecular detection in living cells. | Zheng D, Seferos DS, Giljohann DA, Patel PC, Mirkin CA | Nano letters | 19645478 | Nano Lett | 2009 Sep |
Plasmon-mediated synthesis of silver triangular bipyramids. | Zhang J, Li S, Wu J, Schatz GC, Mirkin CA | Angewandte Chemie (International ed. in English) | 19760687 | Angew Chem Int Ed Engl | 2009 |
Regulating immune response using polyvalent nucleic acid-gold nanoparticle conjugates. | Massich MD, Giljohann DA, Seferos DS, Ludlow LE, Horvath CM, Mirkin CA | Molecular pharmaceutics | 19810673 | Mol Pharm | 2009 Nov-Dec |
Multiplexed protein arrays enabled by polymer pen lithography: addressing the inking challenge. | Zheng Z, Daniel WL, Giam LR, Huo F, Senesi AJ, Zheng G, Mirkin CA | Angewandte Chemie (International ed. in English) | 19731290 | Angew Chem Int Ed Engl | 2009 |
Complementary electrical and spectroscopic detection assays with on-wire-lithography-based nanostructures. | Zheng G, Chen X, Mirkin CA | Small (Weinheim an der Bergstrasse, Germany) | 19697306 | Small | 2009 Nov |
Water-soluble macrocycles synthesized via the weak-link approach. | Wiester MJ, Mirkin CA | Inorganic chemistry | 19637852 | Inorg Chem | 2009 Sep 7 |
In-wire conversion of a metal nanorod segment into an organic semiconductor. | Chen X, Zheng G, Cutler JI, Jang JW, Mirkin CA | Small (Weinheim an der Bergstrasse, Germany) | 19387988 | Small | 2009 Jul |
Triple-Decker Complexes Formed via the Weak Link Approach. | Jeon YM, Heo J, Brown AM, Mirkin CA | Organometallics | 19060957 | Organometallics | 2006 May 22 |
A gold nanoparticle based approach for screening triplex DNA binders. | Han MS, Lytton-Jean AK, Mirkin CA | Journal of the American Chemical Society | 16608320 | J Am Chem Soc | 2006 Apr 19 |
Pyrene-Appended Fluorescent Tweezers Generated via the Weak-Link Approach and Their Halide Recognition Properties. | Jeon YM, Kim D, Mirkin CA, Golen JA, Rheingold AL | Tetrahedron | 22180669 | Tetrahedron | 2008 Sep 1 |
Separation of tricomponent protein mixtures with triblock nanorods. | Oh BK, Park S, Millstone JE, Lee SW, Lee KB, Mirkin CA | Journal of the American Chemical Society | 16953622 | J Am Chem Soc | 2006 Sep 13 |
Asymmetric functionalization of gold nanoparticles with oligonucleotides. | Xu X, Rosi NL, Wang Y, Huo F, Mirkin CA | Journal of the American Chemical Society | 16848436 | J Am Chem Soc | 2006 Jul 26 |
Maximizing DNA loading on a range of gold nanoparticle sizes. | Hurst SJ, Lytton-Jean AK, Mirkin CA | Analytical chemistry | 17165821 | Anal Chem | 2006 Dec 15 |
Dip-pen nanolithography of high-melting-temperature molecules. | Huang L, Chang YH, Kakkassery JJ, Mirkin CA | The journal of physical chemistry. B | 17048882 | J Phys Chem B | 2006 Oct 26 |
DNA-gold triangular nanoprism conjugates. | Millstone JE, Georganopoulou DG, Xu X, Wei W, Li S, Mirkin CA | Small (Weinheim an der Bergstrasse, Germany) | 19016498 | Small | 2008 Dec |
Thermodynamically controlled separation of polyvalent 2-nm gold nanoparticle-oligonucleotide conjugates. | Lee JS, Seferos DS, Giljohann DA, Mirkin CA | Journal of the American Chemical Society | 18370386 | J Am Chem Soc | 2008 Apr 23 |
Polymer pen lithography. | Huo F, Zheng Z, Zheng G, Giam LR, Zhang H, Mirkin CA | Science (New York, N.Y.) | 18703709 | Science | 2008 Sep 19 |
Silver nanoparticle-oligonucleotide conjugates based on DNA with triple cyclic disulfide moieties. | Lee JS, Lytton-Jean AK, Hurst SJ, Mirkin CA | Nano letters | 17571909 | Nano Lett | 2007 Jul |
A new approach to amplified telomerase detection with polyvalent oligonucleotide nanoparticle conjugates. | Zheng G, Daniel WL, Mirkin CA | Journal of the American Chemical Society | 18597453 | J Am Chem Soc | 2008 Jul 30 |
Oligonucleotide loading determines cellular uptake of DNA-modified gold nanoparticles. | Giljohann DA, Seferos DS, Patel PC, Millstone JE, Rosi NL, Mirkin CA | Nano letters | 17997588 | Nano Lett | 2007 Dec |
Nano-flares: probes for transfection and mRNA detection in living cells. | Seferos DS, Giljohann DA, Hill HD, Prigodich AE, Mirkin CA | Journal of the American Chemical Society | 18034495 | J Am Chem Soc | 2007 Dec 19 |
Carborane-based pincers: synthesis and structure of SeBSe and SBS Pd(II) complexes. | Spokoyny AM, Reuter MG, Stern CL, Ratner MA, Seideman T, Mirkin CA | Journal of the American Chemical Society | 19583431 | J Am Chem Soc | 2009 Jul 15 |
Curvature-induced base pair "slipping" effects in DNA-nanoparticle hybridization. | Hill HD, Hurst SJ, Mirkin CA | Nano letters | 19072317 | Nano Lett | 2009 Jan |
Plasmonically controlled nucleic acid dehybridization with gold nanoprisms. | Jones MR, Millstone JE, Giljohann DA, Seferos DS, Young KL, Mirkin CA | Chemphyschem : a European journal of chemical physics and physical chemistry | 19431161 | Chemphyschem | 2009 Jul 13 |
Amorphous Infinite Coordination Polymer Microparticles: A New Class of Selective Hydrogen Storage Materials. | Jeon YM, Armatas GS, Heo J, Kanatzidis MG, Mirkin CA | Advanced materials (Deerfield Beach, Fla.) | 34539086 | Adv Mater | 2008 Jun 4 |
Supramolecular allosteric cofacial porphyrin complexes. | Oliveri CG, Gianneschi NC, Nguyen ST, Mirkin CA, Stern CL, Wawrzak Z, Pink M | Journal of the American Chemical Society | 17165783 | J Am Chem Soc | 2006 Dec 20 |
Mechanistic study of photomediated triangular silver nanoprism growth. | Xue C, Métraux GS, Millstone JE, Mirkin CA | Journal of the American Chemical Society | 18533653 | J Am Chem Soc | 2008 Jul 2 |
Fluorescence recovery assay for the detection of protein-DNA binding. | Xu X, Zhao Z, Qin L, Wei W, Levine JE, Mirkin CA | Analytical chemistry | 18498181 | Anal Chem | 2008 Jul 15 |
Dynamic interconversion of amorphous microparticles and crystalline rods in salen-based homochiral infinite coordination polymers. | Jeon YM, Heo J, Mirkin CA | Journal of the American Chemical Society | 17523645 | J Am Chem Soc | 2007 Jun 20 |
Establishing the design rules for DNA-mediated programmable colloidal crystallization. | Macfarlane RJ, Jones MR, Senesi AJ, Young KL, Lee B, Wu J, Mirkin CA | Angewandte Chemie (International ed. in English) | 20486143 | Angew Chem Int Ed Engl | 2010 Jun 21 |
On-wire lithography: synthesis, encoding and biological applications. | Banholzer MJ, Qin L, Millstone JE, Osberg KD, Mirkin CA | Nature protocols | 19444241 | Nat Protoc | 2009 |
Heteroligated supramolecular coordination complexes formed via the halide-induced ligand rearrangement reaction. | Oliveri CG, Ulmann PA, Wiester MJ, Mirkin CA | Accounts of chemical research | 18642933 | Acc Chem Res | 2008 Dec |
"Three-dimensional hybridization" with polyvalent DNA-gold nanoparticle conjugates. | Hurst SJ, Hill HD, Mirkin CA | Journal of the American Chemical Society | 18710229 | J Am Chem Soc | 2008 Sep 10 |
Colorimetric Cu(2+) detection using DNA-modified gold-nanoparticle aggregates as probes and click chemistry. | Xu X, Daniel WL, Wei W, Mirkin CA | Small (Weinheim an der Bergstrasse, Germany) | 20108231 | Small | 2010 Mar 8 |
Polyvalent DNA nanoparticle conjugates stabilize nucleic acids. | Seferos DS, Prigodich AE, Giljohann DA, Patel PC, Mirkin CA | Nano letters | 19099465 | Nano Lett | 2009 Jan |
Probing dynein and kinesin stepping with mechanical manipulation in a living cell. | Sims PA, Xie XS | Chemphyschem : a European journal of chemical physics and physical chemistry | 19504528 | Chemphyschem | 2009 Jul 13 |
Regulation of a viral proteinase by a peptide and DNA in one-dimensional space: IV. viral proteinase slides along DNA to locate and process its substrates. | Blainey PC, Graziano V, Pérez-Berná AJ, McGrath WJ, Flint SJ, San Martín C, Xie XS, Mangel WF | The Journal of biological chemistry | 23043138 | J Biol Chem | 2013 Jan 18 |
Probing transcription factor dynamics at the single-molecule level in a living cell. | Elf J, Li GW, Xie XS | Science (New York, N.Y.) | 17525339 | Science | 2007 May 25 |
Chemically specific imaging of cryptosporidium oocysts using coherent anti-Stokes Raman scattering (CARS) microscopy. | Murugkar S, Evans CL, Xie XS, Anis H | Journal of microscopy | 19220690 | J Microsc | 2009 Feb |
A stochastic single-molecule event triggers phenotype switching of a bacterial cell. | Choi PJ, Cai L, Frieda K, Xie XS | Science (New York, N.Y.) | 18927393 | Science | 2008 Oct 17 |
Regulation of a viral proteinase by a peptide and DNA in one-dimensional space: II. adenovirus proteinase is activated in an unusual one-dimensional biochemical reaction. | Graziano V, Luo G, Blainey PC, Pérez-Berná AJ, McGrath WJ, Flint SJ, San Martín C, Xie XS, Mangel WF | The Journal of biological chemistry | 23043137 | J Biol Chem | 2013 Jan 18 |
Single-molecule study of DNA polymerization activity of HIV-1 reverse transcriptase on DNA templates. | Kim S, Schroeder CM, Xie XS | Journal of molecular biology | 19968999 | J Mol Biol | 2010 Feb 5 |
Central dogma at the single-molecule level in living cells. | Li GW, Xie XS | Nature | 21776076 | Nature | 2011 Jul 20 |
Modeling spatial correlation of DNA deformation: DNA allostery in protein binding. | Xu X, Ge H, Gu C, Gao YQ, Wang SS, Thio BJ, Hynes JT, Xie XS, Cao J | The journal of physical chemistry. B | 23795567 | J Phys Chem B | 2013 Oct 24 |
Relatively slow stochastic gene-state switching in the presence of positive feedback significantly broadens the region of bimodality through stabilizing the uninduced phenotypic state. | Ge H, Wu P, Qian H, Xie XS | PLoS computational biology | 29529037 | PLoS Comput Biol | 2018 Mar |
Quantifying E. coli proteome and transcriptome with single-molecule sensitivity in single cells. | Taniguchi Y, Choi PJ, Li GW, Chen H, Babu M, Hearn J, Emili A, Xie XS | Science (New York, N.Y.) | 20671182 | Science | 2010 Jul 30 |
Stochastic protein expression in individual cells at the single molecule level. | Cai L, Friedman N, Xie XS | Nature | 16541077 | Nature | 2006 Mar 16 |
Mechanism of transcriptional bursting in bacteria. | Chong S, Chen C, Ge H, Xie XS | Cell | 25036631 | Cell | 2014 Jul 17 |
Multicolored stain-free histopathology with coherent Raman imaging. | Freudiger CW, Pfannl R, Orringer DA, Saar BG, Ji M, Zeng Q, Ottoboni L, Wei Y, Waeber C, Sims JR, De Jager PL, Sagher O, Philbert MA, Xu X, Kesari S, Xie XS, Young GS | Laboratory investigation; a journal of technical methods and pathology | 22906986 | Lab Invest | 2012 Oct |
Regulation of a viral proteinase by a peptide and DNA in one-dimensional space: I. binding to DNA AND to hexon of the precursor to protein VI, pVI, of human adenovirus. | Graziano V, McGrath WJ, Suomalainen M, Greber UF, Freimuth P, Blainey PC, Luo G, Xie XS, Mangel WF | The Journal of biological chemistry | 23043136 | J Biol Chem | 2013 Jan 18 |
Probing allostery through DNA. | Kim S, Broströmer E, Xing D, Jin J, Chong S, Ge H, Wang S, Gu C, Yang L, Gao YQ, Su XD, Sun Y, Xie XS | Science (New York, N.Y.) | 23413354 | Science | 2013 Feb 15 |
Label-free biomedical imaging with high sensitivity by stimulated Raman scattering microscopy. | Freudiger CW, Min W, Saar BG, Lu S, Holtom GR, He C, Tsai JC, Kang JX, Xie XS | Science (New York, N.Y.) | 19095943 | Science | 2008 Dec 19 |
Discovery of a proneurogenic, neuroprotective chemical. | Pieper AA, Xie S, Capota E, Estill SJ, Zhong J, Long JM, Becker GL, Huntington P, Goldman SE, Shen CH, Capota M, Britt JK, Kotti T, Ure K, Brat DJ, Williams NS, MacMillan KS, Naidoo J, Melito L, Hsieh J, De Brabander J, Ready JM, McKnight SL | Cell | 20603013 | Cell | 2010 Jul 9 |
Development of proneurogenic, neuroprotective small molecules. | MacMillan KS, Naidoo J, Liang J, Melito L, Williams NS, Morlock L, Huntington PJ, Estill SJ, Longgood J, Becker GL, McKnight SL, Pieper AA, De Brabander JK, Ready JM | Journal of the American Chemical Society | 21210688 | J Am Chem Soc | 2011 Feb 9 |
Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment. | Naveiras O, Nardi V, Wenzel PL, Hauschka PV, Fahey F, Daley GQ | Nature | 19516257 | Nature | 2009 Jul 9 |
Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies. | Zhu H, Shah S, Shyh-Chang N, Shinoda G, Einhorn WS, Viswanathan SR, Takeuchi A, Grasemann C, Rinn JL, Lopez MF, Hirschhorn JN, Palmert MR, Daley GQ | Nature genetics | 20512147 | Nat Genet | 2010 Jul |
Generation of functional human hepatic endoderm from human induced pluripotent stem cells. | Sullivan GJ, Hay DC, Park IH, Fletcher J, Hannoun Z, Payne CM, Dalgetty D, Black JR, Ross JA, Samuel K, Wang G, Daley GQ, Lee JH, Church GM, Forbes SJ, Iredale JP, Wilmut I | Hepatology (Baltimore, Md.) | 19877180 | Hepatology | 2010 Jan |
9-(Arenethenyl)purines as dual Src/Abl kinase inhibitors targeting the inactive conformation: design, synthesis, and biological evaluation. | Huang WS, Zhu X, Wang Y, Azam M, Wen D, Sundaramoorthi R, Thomas RM, Liu S, Banda G, Lentini SP, Das S, Xu Q, Keats J, Wang F, Wardwell S, Ning Y, Snodgrass JT, Broudy MI, Russian K, Daley GQ, Iuliucci J, Dalgarno DC, Clackson T, Sawyer TK, Shakespeare WC | Journal of medicinal chemistry | 19572547 | J Med Chem | 2009 Aug 13 |
Hematopoietic development from human induced pluripotent stem cells. | Lengerke C, Grauer M, Niebuhr NI, Riedt T, Kanz L, Park IH, Daley GQ | Annals of the New York Academy of Sciences | 19796250 | Ann N Y Acad Sci | 2009 Sep |
Selective blockade of microRNA processing by Lin28. | Viswanathan SR, Daley GQ, Gregory RI | Science (New York, N.Y.) | 18292307 | Science | 2008 Apr 4 |
AP24163 inhibits the gatekeeper mutant of BCR-ABL and suppresses in vitro resistance. | Azam M, Powers JT, Einhorn W, Huang WS, Shakespeare WC, Zhu X, Dalgarno D, Clackson T, Sawyer TK, Daley GQ | Chemical biology & drug design | 20028401 | Chem Biol Drug Des | 2010 Feb |
Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage. | Tulpule A, Lensch MW, Miller JD, Austin K, D'Andrea A, Schlaeger TM, Shimamura A, Daley GQ | Blood | 20089964 | Blood | 2010 Apr 29 |
Lin28 promotes transformation and is associated with advanced human malignancies. | Viswanathan SR, Powers JT, Einhorn W, Hoshida Y, Ng TL, Toffanin S, O'Sullivan M, Lu J, Phillips LA, Lockhart VL, Shah SP, Tanwar PS, Mermel CH, Beroukhim R, Azam M, Teixeira J, Meyerson M, Hughes TP, Llovet JM, Radich J, Mullighan CG, Golub TR, Sorensen PH, Daley GQ | Nature genetics | 19483683 | Nat Genet | 2009 Jul |
Interactions between Cdx genes and retinoic acid modulate early cardiogenesis. | Lengerke C, Wingert R, Beeretz M, Grauer M, Schmidt AG, Konantz M, Daley GQ, Davidson AJ | Developmental biology | 21466798 | Dev Biol | 2011 Jun 1 |
Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients. | Agarwal S, Loh YH, McLoughlin EM, Huang J, Park IH, Miller JD, Huo H, Okuka M, Dos Reis RM, Loewer S, Ng HH, Keefe DL, Goldman FD, Klingelhutz AJ, Liu L, Daley GQ | Nature | 20164838 | Nature | 2010 Mar 11 |
A role for Lin28 in primordial germ-cell development and germ-cell malignancy. | West JA, Viswanathan SR, Yabuuchi A, Cunniff K, Takeuchi A, Park IH, Sero JE, Zhu H, Perez-Atayde A, Frazier AL, Surani MA, Daley GQ | Nature | 19578360 | Nature | 2009 Aug 13 |
Enhanced plating efficiency of trypsin-adapted human embryonic stem cells is reversible and independent of trisomy 12/17. | Chan EM, Yates F, Boyer LF, Schlaeger TM, Daley GQ | Cloning and stem cells | 18241122 | Cloning Stem Cells | 2008 Mar |
Ras-MAPK signaling promotes trophectoderm formation from embryonic stem cells and mouse embryos. | Lu CW, Yabuuchi A, Chen L, Viswanathan S, Kim K, Daley GQ | Nature genetics | 18536715 | Nat Genet | 2008 Jul |
Epigenetic memory in induced pluripotent stem cells. | Kim K, Doi A, Wen B, Ng K, Zhao R, Cahan P, Kim J, Aryee MJ, Ji H, Ehrlich LI, Yabuuchi A, Takeuchi A, Cunniff KC, Hongguang H, McKinney-Freeman S, Naveiras O, Yoon TJ, Irizarry RA, Jung N, Seita J, Hanna J, Murakami P, Jaenisch R, Weissleder R, Orkin SH, Weissman IL, Feinberg AP, Daley GQ | Nature | 20644535 | Nature | 2010 Sep 16 |
Disease-specific induced pluripotent stem cells. | Park IH, Arora N, Huo H, Maherali N, Ahfeldt T, Shimamura A, Lensch MW, Cowan C, Hochedlinger K, Daley GQ | Cell | 18691744 | Cell | 2008 Sep 5 |
Activation of tyrosine kinases by mutation of the gatekeeper threonine. | Azam M, Seeliger MA, Gray NS, Kuriyan J, Daley GQ | Nature structural & molecular biology | 18794843 | Nat Struct Mol Biol | 2008 Oct |
Autologous blood cell therapies from pluripotent stem cells. | Lengerke C, Daley GQ | Blood reviews | 19910091 | Blood Rev | 2010 Jan |
Automated microfluidic chromatin immunoprecipitation from 2,000 cells. | Wu AR, Hiatt JB, Lu R, Attema JL, Lobo NA, Weissman IL, Clarke MF, Quake SR | Lab on a chip | 19417902 | Lab Chip | 2009 May 21 |
Ostwald ripening of clusters during protein crystallization. | Streets AM, Quake SR | Physical review letters | 20482145 | Phys Rev Lett | 2010 Apr 30 |
High throughput automated chromatin immunoprecipitation as a platform for drug screening and antibody validation. | Wu AR, Kawahara TL, Rapicavoli NA, van Riggelen J, Shroff EH, Xu L, Felsher DW, Chang HY, Quake SR | Lab on a chip | 22566096 | Lab Chip | 2012 Jun 21 |
Non-invasive prenatal measurement of the fetal genome. | Fan HC, Gu W, Wang J, Blumenfeld YJ, El-Sayed YY, Quake SR | Nature | 22763444 | Nature | 2012 Jul 19 |
High-throughput sequencing of the zebrafish antibody repertoire. | Weinstein JA, Jiang N, White RA 3rd, Fisher DS, Quake SR | Science (New York, N.Y.) | 19423829 | Science | 2009 May 8 |
Dissecting genomic diversity, one cell at a time. | Blainey PC, Quake SR | Nature methods | 24524132 | Nat Methods | 2014 Jan |
Single cell profiling of circulating tumor cells: transcriptional heterogeneity and diversity from breast cancer cell lines. | Powell AA, Talasaz AH, Zhang H, Coram MA, Reddy A, Deng G, Telli ML, Advani RH, Carlson RW, Mollick JA, Sheth S, Kurian AW, Ford JM, Stockdale FE, Quake SR, Pease RF, Mindrinos MN, Bhanot G, Dairkee SH, Davis RW, Jeffrey SS | PloS one | 22586443 | PLoS One | 2012 |
An in vitro microfluidic approach to generating protein-interaction networks. | Gerber D, Maerkl SJ, Quake SR | Nature methods | 19098921 | Nat Methods | 2009 Jan |
Biocompatibility and reduced drug absorption of sol-gel-treated poly(dimethyl siloxane) for microfluidic cell culture applications. | Gomez-Sjoberg R, Leyrat AA, Houseman BT, Shokat K, Quake SR | Analytical chemistry | 20936785 | Anal Chem | 2010 Nov 1 |
Discovery of a hepatitis C target and its pharmacological inhibitors by microfluidic affinity analysis. | Einav S, Gerber D, Bryson PD, Sklan EH, Elazar M, Maerkl SJ, Glenn JS, Quake SR | Nature biotechnology | 18758449 | Nat Biotechnol | 2008 Sep |
Temporal response of the human virome to immunosuppression and antiviral therapy. | De Vlaminck I, Khush KK, Strehl C, Kohli B, Luikart H, Neff NF, Okamoto J, Snyder TM, Cornfield DN, Nicolls MR, Weill D, Bernstein D, Valantine HA, Quake SR | Cell | 24267896 | Cell | 2013 Nov 21 |
High-performance binary protein interaction screening in a microfluidic format. | Meier M, Sit R, Pan W, Quake SR | Analytical chemistry | 23051662 | Anal Chem | 2012 Nov 6 |
Quantitative analysis of the human airway microbial ecology reveals a pervasive signature for cystic fibrosis. | Blainey PC, Milla CE, Cornfield DN, Quake SR | Science translational medicine | 23019655 | Sci Transl Med | 2012 Sep 26 |
Enhanced signals and fast nucleic acid hybridization by microfluidic chaotic mixing. | Liu J, Williams BA, Gwirtz RM, Wold BJ, Quake S | Angewandte Chemie (International ed. in English) | 16639763 | Angew Chem Int Ed Engl | 2006 May 26 |
High-throughput single-molecule optofluidic analysis. | Kim S, Streets AM, Lin RR, Quake SR, Weiss S, Majumdar DS | Nature methods | 21297618 | Nat Methods | 2011 Mar |
Whole-genome molecular haplotyping of single cells. | Fan HC, Wang J, Potanina A, Quake SR | Nature biotechnology | 21170043 | Nat Biotechnol | 2011 Jan |
A "window of opportunity:" the reduction of coronary heart disease and total mortality with menopausal therapies is age- and time-dependent. | Hodis HN, Mack WJ | Brain research | 20977895 | Brain Res | 2011 Mar 16 |
Versatile, fully automated, microfluidic cell culture system. | Gómez-Sjöberg R, Leyrat AA, Pirone DM, Chen CS, Quake SR | Analytical chemistry | 17953452 | Anal Chem | 2007 Nov 15 |
Noninvasive prenatal diagnosis in a fetus at risk for methylmalonic acidemia. | Gu W, Koh W, Blumenfeld YJ, El-Sayed YY, Hudgins L, Hintz SR, Quake SR | Genetics in medicine : official journal of the American College of Medical Genetics | 24406457 | Genet Med | 2014 Jul |
Single-molecule sequencing of an individual human genome. | Pushkarev D, Neff NF, Quake SR | Nature biotechnology | 19668243 | Nat Biotechnol | 2009 Sep |
Statistical mechanics of Monod-Wyman-Changeux (MWC) models. | Marzen S, Garcia HG, Phillips R | Journal of molecular biology | 23499654 | J Mol Biol | 2013 May 13 |
Comparison of the theoretical and real-world evolutionary potential of a genetic circuit. | Razo-Mejia M, Boedicker JQ, Jones D, DeLuna A, Kinney JB, Phillips R | Physical biology | 24685590 | Phys Biol | 2014 Apr |
Concentration and length dependence of DNA looping in transcriptional regulation. | Han L, Garcia HG, Blumberg S, Towles KB, Beausang JF, Nelson PC, Phillips R | PloS one | 19479049 | PLoS One | 2009 May 25 |
Building enhancers from the ground up: a synthetic biology approach. | Amit R, Garcia HG, Phillips R, Fraser SE | Cell | 21729783 | Cell | 2011 Jul 8 |
Ion-dependent dynamics of DNA ejections for bacteriophage lambda. | Wu D, Van Valen D, Hu Q, Phillips R | Biophysical journal | 20712993 | Biophys J | 2010 Aug 9 |
Biochemistry on a leash: the roles of tether length and geometry in signal integration proteins. | Van Valen D, Haataja M, Phillips R | Biophysical journal | 19217847 | Biophys J | 2009 Feb 18 |
Membrane mechanics as a probe of ion-channel gating mechanisms. | Reeves D, Ursell T, Sens P, Kondev J, Phillips R | Physical review. E, Statistical, nonlinear, and soft matter physics | 18999449 | Phys Rev E Stat Nonlin Soft Matter Phys | 2008 Oct |
A feeling for the numbers in biology. | Phillips R, Milo R | Proceedings of the National Academy of Sciences of the United States of America | 20018695 | Proc Natl Acad Sci U S A | 2009 Dec 22 |
Trajectory approach to two-state kinetics of single particles on sculpted energy landscapes. | Wu D, Ghosh K, Inamdar M, Lee HJ, Fraser S, Dill K, Phillips R | Physical review letters | 19792475 | Phys Rev Lett | 2009 Jul 31 |
Directional interactions and cooperativity between mechanosensitive membrane proteins. | Haselwandter CA, Phillips R | Europhysics letters | 25309021 | Europhys Lett | 2013 Mar |
Single-cell census of mechanosensitive channels in living bacteria. | Bialecka-Fornal M, Lee HJ, DeBerg HA, Gandhi CS, Phillips R | PloS one | 22427953 | PLoS One | 2012 |
Entropic tension in crowded membranes. | Lindén M, Sens P, Phillips R | PLoS computational biology | 22438801 | PLoS Comput Biol | 2012 |
Comparison and calibration of different reporters for quantitative analysis of gene expression. | Garcia HG, Lee HJ, Boedicker JQ, Phillips R | Biophysical journal | 21806921 | Biophys J | 2011 Aug 3 |
Elastic energy of polyhedral bilayer vesicles. | Haselwandter CA, Phillips R | Physical review. E, Statistical, nonlinear, and soft matter physics | 21797397 | Phys Rev E Stat Nonlin Soft Matter Phys | 2011 Jun |
Effect of promoter architecture on the cell-to-cell variability in gene expression. | Sanchez A, Garcia HG, Jones D, Phillips R, Kondev J | PLoS computational biology | 21390269 | PLoS Comput Biol | 2011 Mar |
Connection between oligomeric state and gating characteristics of mechanosensitive ion channels. | Haselwandter CA, Phillips R | PLoS computational biology | 23696720 | PLoS Comput Biol | 2013 |
Poly(dA:dT)-rich DNAs are highly flexible in the context of DNA looping. | Johnson S, Chen YJ, Phillips R | PloS one | 24146776 | PLoS One | 2013 |
Teaching the principles of statistical dynamics. | Ghosh K, Dill KA, Inamdar MM, Seitaridou E, Phillips R | American journal of physics | 23585693 | Am J Phys | 2006 Feb 1 |
Monod-Wyman-Changeux Analysis of Ligand-Gated Ion Channel Mutants. | Einav T, Phillips R | The journal of physical chemistry. B | 28134524 | J Phys Chem B | 2017 Apr 20 |
Theoretical analysis of inducer and operator binding for cyclic-AMP receptor protein mutants. | Einav T, Duque J, Phillips R | PloS one | 30256816 | PLoS One | 2018 |
Musings on mechanism: quest for a quark theory of proteins? | Phillips R | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 28963318 | FASEB J | 2017 Oct |
Mapping DNA sequence to transcription factor binding energy in vivo. | Barnes SL, Belliveau NM, Ireland WT, Kinney JB, Phillips R | PLoS computational biology | 30716072 | PLoS Comput Biol | 2019 Feb |
Design Principles of Length Control of Cytoskeletal Structures. | Mohapatra L, Goode BL, Jelenkovic P, Phillips R, Kondev J | Annual review of biophysics | 27145876 | Annu Rev Biophys | 2016 Jul 5 |
Interplay of Protein Binding Interactions, DNA Mechanics, and Entropy in DNA Looping Kinetics. | Mulligan PJ, Chen YJ, Phillips R, Spakowitz AJ | Biophysical journal | 26244743 | Biophys J | 2015 Aug 4 |
Morphological phase diagram for lipid membrane domains with entropic tension. | Rim JE, Ursell TS, Phillips R, Klug WS | Physical review letters | 21405437 | Phys Rev Lett | 2011 Feb 4 |
Sequence dependence of transcription factor-mediated DNA looping. | Johnson S, Lindén M, Phillips R | Nucleic acids research | 22718983 | Nucleic Acids Res | 2012 Sep |
Real-time observations of single bacteriophage lambda DNA ejections in vitro. | Grayson P, Han L, Winther T, Phillips R | Proceedings of the National Academy of Sciences of the United States of America | 17804798 | Proc Natl Acad Sci U S A | 2007 Sep 11 |
Transcriptional regulation by the numbers: applications. | Bintu L, Buchler NE, Garcia HG, Gerland U, Hwa T, Kondev J, Kuhlman T, Phillips R | Current opinion in genetics & development | 15797195 | Curr Opin Genet Dev | 2005 Apr |
The effect of genome length on ejection forces in bacteriophage lambda. | Grayson P, Evilevitch A, Inamdar MM, Purohit PK, Gelbart WM, Knobler CM, Phillips R | Virology | 16469346 | Virology | 2006 May 10 |
Reduced amino acid alphabets exhibit an improved sensitivity and selectivity in fold assignment. | Peterson EL, Kondev J, Theriot JA, Phillips R | Bioinformatics (Oxford, England) | 19351620 | Bioinformatics | 2009 Jun 1 |
Morphology and interaction between lipid domains. | Ursell TS, Klug WS, Phillips R | Proceedings of the National Academy of Sciences of the United States of America | 19620730 | Proc Natl Acad Sci U S A | 2009 Aug 11 |
Emerging roles for lipids in shaping membrane-protein function. | Phillips R, Ursell T, Wiggins P, Sens P | Nature | 19458714 | Nature | 2009 May 21 |
Cooperative gating and spatial organization of membrane proteins through elastic interactions. | Ursell T, Huang KC, Peterson E, Phillips R | PLoS computational biology | 17480116 | PLoS Comput Biol | 2007 May |
Thermodynamics of biological processes. | Garcia HG, Kondev J, Orme N, Theriot JA, Phillips R | Methods in enzymology | 21333788 | Methods Enzymol | 2011 |
Transcription by the numbers redux: experiments and calculations that surprise. | Garcia HG, Sanchez A, Kuhlman T, Kondev J, Phillips R | Trends in cell biology | 20801657 | Trends Cell Biol | 2010 Dec |
Statistical Mechanics of Allosteric Enzymes. | Einav T, Mazutis L, Phillips R | The journal of physical chemistry. B | 27070509 | J Phys Chem B | 2016 Jul 7 |
Tuning Transcriptional Regulation through Signaling: A Predictive Theory of Allosteric Induction. | Razo-Mejia M, Barnes SL, Belliveau NM, Chure G, Einav T, Lewis M, Phillips R | Cell systems | 29574055 | Cell Syst | 2018 Apr 25 |
Promoter architecture dictates cell-to-cell variability in gene expression. | Jones DL, Brewster RC, Phillips R | Science (New York, N.Y.) | 25525251 | Science | 2014 Dec 19 |
Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation. | Ngo HB, Lovely GA, Phillips R, Chan DC | Nature communications | 24435062 | Nat Commun | 2014 |
DNA sequence-dependent mechanics and protein-assisted bending in repressor-mediated loop formation. | Boedicker JQ, Garcia HG, Johnson S, Phillips R | Physical biology | 24231252 | Phys Biol | 2013 Dec |
Tuning promoter strength through RNA polymerase binding site design in Escherichia coli. | Brewster RC, Jones DL, Phillips R | PLoS computational biology | 23271961 | PLoS Comput Biol | 2012 |
Theoretical and experimental dissection of DNA loop-mediated repression. | Boedicker JQ, Garcia HG, Phillips R | Physical review letters | 23383841 | Phys Rev Lett | 2013 Jan 4 |
Predicting the impact of promoter variability on regulatory outputs. | Kreamer NN, Phillips R, Newman DK, Boedicker JQ | Scientific reports | 26675057 | Sci Rep | 2015 Dec 17 |
Figure 1 Theory Meets Figure 2 Experiments in the Study of Gene Expression. | Phillips R, Belliveau NM, Chure G, Garcia HG, Razo-Mejia M, Scholes C | Annual review of biophysics | 31084583 | Annu Rev Biophys | 2019 May 6 |
Predictive shifts in free energy couple mutations to their phenotypic consequences. | Chure G, Razo-Mejia M, Belliveau NM, Einav T, Kaczmarek ZA, Barnes SL, Lewis M, Phillips R | Proceedings of the National Academy of Sciences of the United States of America | 31451655 | Proc Natl Acad Sci U S A | 2019 Sep 10 |
Anionic Lipids Impact RAS-Binding Site Accessibility and Membrane Binding Affinity of CRAF RBD-CRD. | Travers T, López CA, Agamasu C, Hettige JJ, Messing S, García AE, Stephen AG, Gnanakaran S | Biophysical journal | 32649863 | Biophys J | 2020 Aug 4 |
Statistical mechanical model of coupled transcription from multiple promoters due to transcription factor titration. | Rydenfelt M, Cox RS 3rd, Garcia H, Phillips R | Physical review. E, Statistical, nonlinear, and soft matter physics | 24580252 | Phys Rev E Stat Nonlin Soft Matter Phys | 2014 Jan |
The transcription factor titration effect dictates level of gene expression. | Brewster RC, Weinert FM, Garcia HG, Song D, Rydenfelt M, Phillips R | Cell | 24612990 | Cell | 2014 Mar 13 |
Biological consequences of tightly bent DNA: the other life of a macromolecular celebrity. | Garcia HG, Grayson P, Han L, Inamdar M, Kondev J, Nelson PC, Phillips R, Widom J, Wiggins PA | Biopolymers | 17103419 | Biopolymers | 2007 Feb 5 |
Transcriptional regulation by the numbers: models. | Bintu L, Buchler NE, Garcia HG, Gerland U, Hwa T, Kondev J, Phillips R | Current opinion in genetics & development | 15797194 | Curr Opin Genet Dev | 2005 Apr |
A single-molecule Hershey-Chase experiment. | Van Valen D, Wu D, Chen YJ, Tuson H, Wiggins P, Phillips R | Current biology : CB | 22727695 | Curr Biol | 2012 Jul 24 |
Measuring flux distributions for diffusion in the small-numbers limit. | Seitaridou E, Inamdar MM, Phillips R, Ghosh K, Dill K | The journal of physical chemistry. B | 17295536 | J Phys Chem B | 2007 Mar 8 |
First-principles calculation of DNA looping in tethered particle experiments. | Towles KB, Beausang JF, Garcia HG, Phillips R, Nelson PC | Physical biology | 19571369 | Phys Biol | 2009 Jul 1 |
Minimal bending energies of bilayer polyhedra. | Haselwandter CA, Phillips R | Physical review letters | 21231425 | Phys Rev Lett | 2010 Nov 26 |
Using synthetic biology to make cells tomorrow's test tubes. | Garcia HG, Brewster RC, Phillips R | Integrative biology : quantitative biosciences from nano to macro | 26952708 | Integr Biol (Camb) | 2016 Apr 18 |
Napoleon Is in Equilibrium. | Phillips R | Annual review of condensed matter physics | 27429713 | Annu Rev Condens Matter Phys | 2015 Mar |
The influence of promoter architectures and regulatory motifs on gene expression in Escherichia coli. | Rydenfelt M, Garcia HG, Cox RS 3rd, Phillips R | PloS one | 25549361 | PLoS One | 2014 |
Schrödinger's What Is Life? at 75. | Phillips R | Cell systems | 34139159 | Cell Syst | 2021 Jun 16 |
Combinatorial Control through Allostery. | Galstyan V, Funk L, Einav T, Phillips R | The journal of physical chemistry. B | 30768906 | J Phys Chem B | 2019 Apr 4 |
Exact theory of kinkable elastic polymers. | Wiggins PA, Phillips R, Nelson PC | Physical review. E, Statistical, nonlinear, and soft matter physics | 15783354 | Phys Rev E Stat Nonlin Soft Matter Phys | 2005 Feb |
Volume-exclusion effects in tethered-particle experiments: bead size matters. | Segall DE, Nelson PC, Phillips R | Physical review letters | 16606235 | Phys Rev Lett | 2006 Mar 3 |
Dynamics of DNA ejection from bacteriophage. | Inamdar MM, Gelbart WM, Phillips R | Biophysical journal | 16679360 | Biophys J | 2006 Jul 15 |
The rate of osmotic downshock determines the survival probability of bacterial mechanosensitive channel mutants. | Bialecka-Fornal M, Lee HJ, Phillips R | Journal of bacteriology | 25349158 | J Bacteriol | 2015 Jan 1 |
Scaling of gene expression with transcription-factor fugacity. | Weinert FM, Brewster RC, Rydenfelt M, Phillips R, Kegel WK | Physical review letters | 25554908 | Phys Rev Lett | 2014 Dec 19 |
Deciphering the regulatory genome of Escherichia coli, one hundred promoters at a time. | Ireland WT, Beeler SM, Flores-Bautista E, McCarty NS, Röschinger T, Belliveau NM, Sweredoski MJ, Moradian A, Kinney JB, Phillips R | eLife | 32955440 | Elife | 2020 Sep 21 |
Theory in Biology: Figure 1 or Figure 7? | Phillips R | Trends in cell biology | 26584768 | Trends Cell Biol | 2015 Dec |
Probing individual environmental bacteria for viruses by using microfluidic digital PCR. | Tadmor AD, Ottesen EA, Leadbetter JR, Phillips R | Science (New York, N.Y.) | 21719670 | Science | 2011 Jul 1 |
Quantitative dissection of the simple repression input-output function. | Garcia HG, Phillips R | Proceedings of the National Academy of Sciences of the United States of America | 21730194 | Proc Natl Acad Sci U S A | 2011 Jul 19 |
Connecting the Dots between Mechanosensitive Channel Abundance, Osmotic Shock, and Survival at Single-Cell Resolution. | Chure G, Lee HJ, Rasmussen A, Phillips R | Journal of bacteriology | 30201782 | J Bacteriol | 2018 Dec 1 |
Systematic approach for dissecting the molecular mechanisms of transcriptional regulation in bacteria. | Belliveau NM, Barnes SL, Ireland WT, Jones DL, Sweredoski MJ, Moradian A, Hess S, Kinney JB, Phillips R | Proceedings of the National Academy of Sciences of the United States of America | 29728462 | Proc Natl Acad Sci U S A | 2018 May 22 |
Operator sequence alters gene expression independently of transcription factor occupancy in bacteria. | Garcia HG, Sanchez A, Boedicker JQ, Osborne M, Gelles J, Kondev J, Phillips R | Cell reports | 22840405 | Cell Rep | 2012 Jul 26 |
Self-consistent theory of transcriptional control in complex regulatory architectures. | Landman J, Brewster RC, Weinert FM, Phillips R, Kegel WK | PloS one | 28686609 | PLoS One | 2017 |
Binding and signaling of surface-immobilized reagentless fluorescent biosensors derived from periplasmic binding proteins. | de Lorimier RM, Tian Y, Hellinga HW | Protein science : a publication of the Protein Society | 16823040 | Protein Sci | 2006 Aug |
A miniaturized technique for assessing protein thermodynamics and function using fast determination of quantitative cysteine reactivity. | Isom DG, Marguet PR, Oas TG, Hellinga HW | Proteins | 21387407 | Proteins | 2011 Apr |
The backbone structure of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein is essentially identical to its mesophilic E. coli homolog. | Cuneo MJ, Tian Y, Allert M, Hellinga HW | BMC structural biology | 18373848 | BMC Struct Biol | 2008 Mar 28 |
Structural adaptations that modulate monosaccharide, disaccharide, and trisaccharide specificities in periplasmic maltose-binding proteins. | Cuneo MJ, Changela A, Beese LS, Hellinga HW | Journal of molecular biology | 19361522 | J Mol Biol | 2009 May 29 |
Local encoding of computationally designed enzyme activity. | Allert M, Dwyer MA, Hellinga HW | Journal of molecular biology | 17196220 | J Mol Biol | 2007 Feb 23 |
Identification of cognate ligands for the Escherichia coli phnD protein product and engineering of a reagentless fluorescent biosensor for phosphonates. | Rizk SS, Cuneo MJ, Hellinga HW | Protein science : a publication of the Protein Society | 16751609 | Protein Sci | 2006 Jul |
Wharton's Jelly Mesenchymal Stromal Cells and Derived Extracellular Vesicles as Post-Myocardial Infarction Therapeutic Toolkit: An Experienced View. | Muñoz-Domínguez N, Roura S, Prat-Vidal C, Vives J | Pharmaceutics | 34575412 | Pharmaceutics | 2021 Aug 26 |
The crystal structure of a thermophilic glucose binding protein reveals adaptations that interconvert mono and di-saccharide binding sites. | Cuneo MJ, Changela A, Warren JJ, Beese LS, Hellinga HW | Journal of molecular biology | 16904687 | J Mol Biol | 2006 Sep 15 |
Protein fabrication automation. | Cox JC, Lape J, Sayed MA, Hellinga HW | Protein science : a publication of the Protein Society | 17242375 | Protein Sci | 2007 Mar |
Structure-based design of robust glucose biosensors using a Thermotoga maritima periplasmic glucose-binding protein. | Tian Y, Cuneo MJ, Changela A, Höcker B, Beese LS, Hellinga HW | Protein science : a publication of the Protein Society | 17766373 | Protein Sci | 2007 Oct |
Picomole-scale characterization of protein stability and function by quantitative cysteine reactivity. | Isom DG, Vardy E, Oas TG, Hellinga HW | Proceedings of the National Academy of Sciences of the United States of America | 20194783 | Proc Natl Acad Sci U S A | 2010 Mar 16 |
Structural analysis of semi-specific oligosaccharide recognition by a cellulose-binding protein of thermotoga maritima reveals adaptations for functional diversification of the oligopeptide periplasmic binding protein fold. | Cuneo MJ, Beese LS, Hellinga HW | The Journal of biological chemistry | 19801540 | J Biol Chem | 2009 Nov 27 |
Structural analysis of a periplasmic binding protein in the tripartite ATP-independent transporter family reveals a tetrameric assembly that may have a role in ligand transport. | Cuneo MJ, Changela A, Miklos AE, Beese LS, Krueger JK, Hellinga HW | The Journal of biological chemistry | 18723845 | J Biol Chem | 2008 Nov 21 |
Visualization of synaptic inhibition with an optogenetic sensor developed by cell-free protein engineering automation. | Grimley JS, Li L, Wang W, Wen L, Beese LS, Hellinga HW, Augustine GJ | The Journal of neuroscience : the official journal of the Society for Neuroscience | 24107961 | J Neurosci | 2013 Oct 9 |
Multifactorial determinants of protein expression in prokaryotic open reading frames. | Allert M, Cox JC, Hellinga HW | Journal of molecular biology | 20727358 | J Mol Biol | 2010 Oct 8 |
Ligand-induced conformational changes in a thermophilic ribose-binding protein. | Cuneo MJ, Beese LS, Hellinga HW | BMC structural biology | 19019243 | BMC Struct Biol | 2008 Nov 19 |
Thermodynamic analysis of ligand-induced changes in protein thermal unfolding applied to high-throughput determination of ligand affinities with extrinsic fluorescent dyes. | Layton CJ, Hellinga HW | Biochemistry | 21050007 | Biochemistry | 2010 Dec 28 |
Integration of cell-free protein coexpression with an enzyme-linked immunosorbent assay enables rapid analysis of protein-protein interactions directly from DNA. | Layton CJ, Hellinga HW | Protein science : a publication of the Protein Society | 21674663 | Protein Sci | 2011 Aug |
Generating coherent patterns of activity from chaotic neural networks. | Sussillo D, Abbott LF | Neuron | 19709635 | Neuron | 2009 Aug 27 |
HCN hyperpolarization-activated cation channels inhibit EPSPs by interactions with M-type K(+) channels. | George MS, Abbott LF, Siegelbaum SA | Nature neuroscience | 19363490 | Nat Neurosci | 2009 May |
Stimulus-dependent suppression of chaos in recurrent neural networks. | Rajan K, Abbott LF, Sompolinsky H | Physical review. E, Statistical, nonlinear, and soft matter physics | 20866644 | Phys Rev E Stat Nonlin Soft Matter Phys | 2010 Jul |
Modular realignment of entorhinal grid cell activity as a basis for hippocampal remapping. | Monaco JD, Abbott LF | The Journal of neuroscience : the official journal of the Society for Neuroscience | 21697391 | J Neurosci | 2011 Jun 22 |
Gating multiple signals through detailed balance of excitation and inhibition in spiking networks. | Vogels TP, Abbott LF | Nature neuroscience | 19305402 | Nat Neurosci | 2009 Apr |
A brainstem map of orofacial rhythms. | Kaku H, Liu LD, Gao R, West S, Liao SM, Finkelstein A, Kleinfeld D, Thomas A, Tipparaju SL, Svoboda K, Li N | bioRxiv : the preprint server for biology | 39975015 | bioRxiv | 2025 Jan 27 |
A frugal CRISPR kit for equitable and accessible education in gene editing and synthetic biology. | Collins M, Lau MB, Ma W, Shen A, Wang B, Cai S, La Russa M, Jewett MC, Qi LS | Nature communications | 39095367 | Nat Commun | 2024 Aug 3 |
The realization of CRISPR gene therapy. | Ma Y, Qi LS | Nature chemical biology | 38872012 | Nat Chem Biol | 2024 Jul |
Cortical activity emerges in region-specific patterns during early brain development. | Suárez R, Bluett T, McCullough MH, Avitan L, Black DA, Paolino A, Fenlon LR, Goodhill GJ, Richards LJ | bioRxiv : the preprint server for biology | 36824827 | bioRxiv | 2023 Apr 8 |
Diverse axonal morphologies of individual callosal projection neurons reveal new insights into brain connectivity. | Pal S, Lim JWC, Richards LJ | Current opinion in neurobiology | 38271848 | Curr Opin Neurobiol | 2024 Feb |
Cortical activity emerges in region-specific patterns during early brain development. | Suárez R, Bluett T, McCullough MH, Avitan L, Black DA, Paolino A, Fenlon LR, Goodhill GJ, Richards LJ | Proceedings of the National Academy of Sciences of the United States of America | 37216522 | Proc Natl Acad Sci U S A | 2023 May 30 |
Low-field MRI: Clinical promise and challenges. | Arnold TC, Freeman CW, Litt B, Stein JM | Journal of magnetic resonance imaging : JMRI | 36120962 | J Magn Reson Imaging | 2023 Jan |
A framework For brain atlases: Lessons from seizure dynamics. | Revell AY, Silva AB, Arnold TC, Stein JM, Das SR, Shinohara RT, Bassett DS, Litt B, Davis KA | NeuroImage | 35339683 | Neuroimage | 2022 Jul 1 |
Seizure Detection in Continuous Inpatient EEG: A Comparison of Human vs Automated Review. | Ganguly TM, Ellis CA, Tu D, Shinohara RT, Davis KA, Litt B, Pathmanathan J | Neurology | 35410905 | Neurology | 2022 May 31 |
Development of a natural language processing algorithm to extract seizure types and frequencies from the electronic health record. | Decker BM, Turco A, Xu J, Terman SW, Kosaraju N, Jamil A, Davis KA, Litt B, Ellis CA, Khankhanian P, Hill CE | Seizure | 35882104 | Seizure | 2022 Oct |
Spike patterns surrounding sleep and seizures localize the seizure-onset zone in focal epilepsy. | Conrad EC, Revell AY, Greenblatt AS, Gallagher RS, Pattnaik AR, Hartmann N, Gugger JJ, Shinohara RT, Litt B, Marsh ED, Davis KA | Epilepsia | 36484572 | Epilepsia | 2023 Mar |
A pharmacokinetic model of antiseizure medication load to guide care in the epilepsy monitoring unit. | Ghosn NJ, Xie K, Pattnaik AR, Gugger JJ, Ellis CA, Sweeney E, Fox E, Bernabei JM, Johnson J, Boccanfuso J, Litt B, Conrad EC | Epilepsia | 36815252 | Epilepsia | 2023 May |
Quantitative approaches to guide epilepsy surgery from intracranial EEG. | Bernabei JM, Li A, Revell AY, Smith RJ, Gunnarsdottir KM, Ong IZ, Davis KA, Sinha N, Sarma S, Litt B | Brain : a journal of neurology | 36623936 | Brain | 2023 Jun 1 |
iEEG-recon: A fast and scalable pipeline for accurate reconstruction of intracranial electrodes and implantable devices. | Lucas A, Scheid BH, Pattnaik AR, Gallagher R, Mojena M, Tranquille A, Prager B, Gleichgerrcht E, Gong R, Litt B, Davis KA, Das S, Stein JM, Sinha N | Epilepsia | 38148517 | Epilepsia | 2024 Mar |
Artificial intelligence in epilepsy phenotyping. | Knight A, Gschwind T, Galer P, Worrell GA, Litt B, Soltesz I, Beniczky S | Epilepsia | 37983589 | Epilepsia | 2023 Nov 20 |
MXene-infused bioelectronic interfaces for multiscale electrophysiology and stimulation. | Driscoll N, Erickson B, Murphy BB, Richardson AG, Robbins G, Apollo NV, Mentzelopoulos G, Mathis T, Hantanasirisakul K, Bagga P, Gullbrand SE, Sergison M, Reddy R, Wolf JA, Chen HI, Lucas TH, Dillingham TR, Davis KA, Gogotsi Y, Medaglia JD, Vitale F | Science translational medicine | 34550728 | Sci Transl Med | 2021 Sep 22 |
Fractional-order model predictive control as a framework for electrical neurostimulation in epilepsy. | Chatterjee S, Romero O, Ashourvan A, Pequito S | Journal of neural engineering | 33142281 | J Neural Eng | 2020 Dec 16 |
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Intracranial electroencephalographic biomarker predicts effective responsive neurostimulation for epilepsy prior to treatment. | Scheid BH, Bernabei JM, Khambhati AN, Mouchtaris S, Jeschke J, Bassett DS, Becker D, Davis KA, Lucas T, Doyle W, Chang EF, Friedman D, Rao VR, Litt B | Epilepsia | 34997577 | Epilepsia | 2022 Mar |
Generalization of finetuned transformer language models to new clinical contexts. | Xie K, Terman SW, Gallagher RS, Hill CE, Davis KA, Litt B, Roth D, Ellis CA | JAMIA open | 37600072 | JAMIA Open | 2023 Oct |
Resting-state background features demonstrate multidien cycles in long-term EEG device recordings. | Ojemann WKS, Scheid BH, Mouchtaris S, Lucas A, LaRocque JJ, Aguila C, Ashourvan A, Caciagli L, Davis KA, Conrad EC, Litt B | medRxiv : the preprint server for health sciences | 37461688 | medRxiv | 2023 Jul 7 |
Long-term epilepsy outcome dynamics revealed by natural language processing of clinic notes. | Xie K, Gallagher RS, Shinohara RT, Xie SX, Hill CE, Conrad EC, Davis KA, Roth D, Litt B, Ellis CA | Epilepsia | 37114472 | Epilepsia | 2023 Jul |
Characterizing the treatment gap in the United States among adult patients with a new diagnosis of epilepsy. | Decker BM, Ellis CA, Schriver E, Fischbein K, Smith D, Moyer JT, Kulick-Soper CV, Mowery D, Litt B, Hill CE | Epilepsia | 37150944 | Epilepsia | 2023 Jul |
iEEG-recon: A Fast and Scalable Pipeline for Accurate Reconstruction of Intracranial Electrodes and Implantable Devices. | Lucas A, Scheid BH, Pattnaik AR, Gallagher R, Mojena M, Tranquille A, Prager B, Gleichgerrcht E, Gong R, Litt B, Davis KA, Das S, Stein JM, Sinha N | medRxiv : the preprint server for health sciences | 37398160 | medRxiv | 2023 Jun 13 |
Quantitative EEG Spectral Features Differentiate Genetic Epilepsies and Predict Neurologic Outcomes. | Galer PD, McKee JL, Ruggiero SM, Kaufman MC, McSalley I, Ganesan S, Ojemann WKS, Gonzalez AK, Cao Q, Litt B, Helbig I, Conrad EC | medRxiv : the preprint server for health sciences | 39417111 | medRxiv | 2024 Oct 10 |
Quantifying interictal intracranial EEG to predict focal epilepsy. | Gallagher RS, Sinha N, Pattnaik AR, Ojemann WKS, Lucas A, LaRocque JJ, Bernabei JM, Greenblatt AS, Sweeney EM, Chen HI, Davis KA, Conrad EC, Litt B | ArXiv | 37547655 | ArXiv | 2023 Jul 27 |
Multi-contrast high-field quality image synthesis for portable low-field MRI using generative adversarial networks and paired data. | Lucas A, Campbell Arnold T, Okar SV, Vadali C, Kawatra KD, Ren Z, Cao Q, Shinohara RT, Schindler MK, Davis KA, Litt B, Reich DS, Stein JM | medRxiv : the preprint server for health sciences | 38234785 | medRxiv | 2023 Dec 29 |
The seizure severity score: a quantitative tool for comparing seizures and their response to therapy. | Pattnaik AR, Ghosn NJ, Ong IZ, Revell AY, Ojemann WKS, Scheid BH, Georgostathi G, Bernabei JM, Conrad EC, Sinha SR, Davis KA, Sinha N, Litt B | Journal of neural engineering | 37531949 | J Neural Eng | 2023 Aug 10 |
Remote effects of temporal lobe epilepsy surgery: Long-term morphological changes after surgical resection. | Arnold TC, Kini LG, Bernabei JM, Revell AY, Das SR, Stein JM, Lucas TH, Englot DJ, Morgan VL, Litt B, Davis KA | Epilepsia open | 36944585 | Epilepsia Open | 2023 Jun |
Time-evolving controllability of effective connectivity networks during seizure progression. | Scheid BH, Ashourvan A, Stiso J, Davis KA, Mikhail F, Pasqualetti F, Litt B, Bassett DS | Proceedings of the National Academy of Sciences of the United States of America | 33495341 | Proc Natl Acad Sci U S A | 2021 Feb 2 |
Implanting intracranial electrodes does not affect spikes or network connectivity in nearby or connected brain regions. | Conrad EC, Shinohara RT, Gugger JJ, Revell AY, Das S, Stein JM, Marsh ED, Davis KA, Litt B | Network neuroscience (Cambridge, Mass.) | 36607198 | Netw Neurosci | 2022 Jul |
Quantifying trial-by-trial variability during cortico-cortical evoked potential mapping of epileptogenic tissue. | Cornblath EJ, Lucas A, Armstrong C, Greenblatt AS, Stein JM, Hadar PN, Raghupathi R, Marsh E, Litt B, Davis KA, Conrad EC | Epilepsia | 36728906 | Epilepsia | 2023 Apr |
Addressing spatial bias in intracranial EEG functional connectivity analyses for epilepsy surgical planning. | Conrad EC, Bernabei JM, Sinha N, Ghosn NJ, Stein JM, Shinohara RT, Litt B | Journal of neural engineering | 36084621 | J Neural Eng | 2022 Sep 23 |
A Full-Stack Application for Detecting Seizures and Reducing Data During Continuous Electroencephalogram Monitoring. | Bernabei JM, Owoputi O, Small SD, Nyema NT, Dumenyo E, Kim J, Baldassano SN, Painter C, Conrad EC, Ganguly TM, Balu R, Davis KA, Levine JM, Pathmanathan J, Litt B | Critical care explorations | 34278312 | Crit Care Explor | 2021 Jul |
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On-Demand Seizures Facilitate Rapid Screening of Therapeutics for Epilepsy. | Chen Y, Litt B, Vitale F, Takano H | bioRxiv : the preprint server for biology | 39464023 | bioRxiv | 2024 Oct 15 |
Electrocorticography and stereo EEG provide distinct measures of brain connectivity: implications for network models. | Bernabei JM, Arnold TC, Shah P, Revell A, Ong IZ, Kini LG, Stein JM, Shinohara RT, Lucas TH, Davis KA, Bassett DS, Litt B | Brain communications | 34396112 | Brain Commun | 2021 |
Normative intracranial EEG maps epileptogenic tissues in focal epilepsy. | Bernabei JM, Sinha N, Arnold TC, Conrad E, Ong I, Pattnaik AR, Stein JM, Shinohara RT, Lucas TH, Bassett DS, Davis KA, Litt B | Brain : a journal of neurology | 35640886 | Brain | 2022 Jun 30 |
Sensitivity of portable low-field magnetic resonance imaging for multiple sclerosis lesions. | Arnold TC, Tu D, Okar SV, Nair G, By S, Kawatra KD, Robert-Fitzgerald TE, Desiderio LM, Schindler MK, Shinohara RT, Reich DS, Stein JM | NeuroImage. Clinical | 35792417 | Neuroimage Clin | 2022 |
Model-based design for seizure control by stimulation. | Ashourvan A, Pequito S, Khambhati AN, Mikhail F, Baldassano SN, Davis KA, Lucas TH, Vettel JM, Litt B, Pappas GJ, Bassett DS | Journal of neural engineering | 32103826 | J Neural Eng | 2020 Mar 26 |
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Alcohol for seizure induction in the epilepsy monitoring unit. | Emmert BE, Xie K, Conrad EC, Ghosn NJ, Bauman K, Korzun J, Kulick-Soper CV, Naveed O, Hartmann N, LaRocque JJ, Mindy Ganguly T, Gugger JJ, Raghupathi R, Gelfand MA, Davis KA, Sinha SR, Litt B, Shinohara RT, Ellis CA | Epilepsy & behavior : E&B | 38070406 | Epilepsy Behav | 2024 Jan |
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Glioblastoma remodelling of human neural circuits decreases survival. | Krishna S, Choudhury A, Keough MB, Seo K, Ni L, Kakaizada S, Lee A, Aabedi A, Popova G, Lipkin B, Cao C, Nava Gonzales C, Sudharshan R, Egladyous A, Almeida N, Zhang Y, Molinaro AM, Venkatesh HS, Daniel AGS, Shamardani K, Hyer J, Chang EF, Findlay A, Phillips JJ, Nagarajan S, Raleigh DR, Brang D, Monje M, Hervey-Jumper SL | Nature | 37138086 | Nature | 2023 May |
Loss of Adaptive Myelination Contributes to Methotrexate Chemotherapy-Related Cognitive Impairment. | Geraghty AC, Gibson EM, Ghanem RA, Greene JJ, Ocampo A, Goldstein AK, Ni L, Yang T, Marton RM, Paşca SP, Greenberg ME, Longo FM, Monje M | Neuron | 31122677 | Neuron | 2019 Jul 17 |
Diffuse Intrinsic Pontine Glioma: From Diagnosis to Next-Generation Clinical Trials. | Vitanza NA, Monje M | Current treatment options in neurology | 31290035 | Curr Treat Options Neurol | 2019 Jul 10 |
A prognostic neural epigenetic signature in high-grade glioma. | Drexler R, Khatri R, Sauvigny T, Mohme M, Maire CL, Ryba A, Zghaibeh Y, Dührsen L, Salviano-Silva A, Lamszus K, Westphal M, Gempt J, Wefers AK, Neumann JE, Bode H, Hausmann F, Huber TB, Bonn S, Jütten K, Delev D, Weber KJ, Harter PN, Onken J, Vajkoczy P, Capper D, Wiestler B, Weller M, Snijder B, Buck A, Weiss T, Göller PC, Sahm F, Menstel JA, Zimmer DN, Keough MB, Ni L, Monje M, Silverbush D, Hovestadt V, Suvà ML, Krishna S, Hervey-Jumper SL, Schüller U, Heiland DH, Hänzelmann S, Ricklefs FL | Nature medicine | 38760585 | Nat Med | 2024 Jun |
Remote neuronal activity drives glioma infiltration via Sema4f. | Huang-Hobbs E, Cheng YT, Ko Y, Luna-Figueroa E, Lozzi B, Taylor KR, McDonald M, He P, Chen HC, Yang Y, Maleki E, Lee ZF, Murali S, Williamson M, Choi D, Curry R, Bayley J, Woo J, Jalali A, Monje M, Noebels JL, Harmanci AS, Rao G, Deneen B | bioRxiv : the preprint server for biology | 36993539 | bioRxiv | 2023 Mar 16 |
Cancer hallmarks intersect with neuroscience in the tumor microenvironment. | Hanahan D, Monje M | Cancer cell | 36917953 | Cancer Cell | 2023 Mar 13 |
Glioma synapses recruit mechanisms of adaptive plasticity. | Taylor KR, Barron T, Hui A, Spitzer A, Yalçin B, Ivec AE, Geraghty AC, Hartmann GG, Arzt M, Gillespie SM, Kim YS, Maleki Jahan S, Zhang H, Shamardani K, Su M, Ni L, Du PP, Woo PJ, Silva-Torres A, Venkatesh HS, Mancusi R, Ponnuswami A, Mulinyawe S, Keough MB, Chau I, Aziz-Bose R, Tirosh I, Suvà ML, Monje M | Nature | 37914930 | Nature | 2023 Nov |
Cholinergic Neuronal Activity Promotes Diffuse Midline Glioma Growth through Muscarinic Signaling. | Drexler R, Drinnenberg A, Gavish A, Yalcin B, Shamardani K, Rogers A, Mancusi R, Taylor KR, Kim YS, Woo PJ, Ravel A, Tatlock E, Ramakrishnan C, Ayala-Sarmiento AE, Pacheco DRF, Siverts L, Daigle TL, Tasic B, Zeng H, Breunig JJ, Deisseroth K, Monje M | bioRxiv : the preprint server for biology | 39386427 | bioRxiv | 2024 Sep 24 |
Therapeutic strategies for diffuse midline glioma from high-throughput combination drug screening. | Lin GL, Wilson KM, Ceribelli M, Stanton BZ, Woo PJ, Kreimer S, Qin EY, Zhang X, Lennon J, Nagaraja S, Morris PJ, Quezada M, Gillespie SM, Duveau DY, Michalowski AM, Shinn P, Guha R, Ferrer M, Klumpp-Thomas C, Michael S, McKnight C, Minhas P, Itkin Z, Raabe EH, Chen L, Ghanem R, Geraghty AC, Ni L, Andreasson KI, Vitanza NA, Warren KE, Thomas CJ, Monje M | Science translational medicine | 31748226 | Sci Transl Med | 2019 Nov 20 |
Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State. | Nagaraja S, Quezada MA, Gillespie SM, Arzt M, Lennon JJ, Woo PJ, Hovestadt V, Kambhampati M, Filbin MG, Suva ML, Nazarian J, Monje M | Molecular cell | 31588023 | Mol Cell | 2019 Dec 19 |
The bright and the dark side of myelin plasticity: Neuron-glial interactions in health and disease. | Monje M, Káradóttir RT | Seminars in cell & developmental biology | 33293232 | Semin Cell Dev Biol | 2021 Aug |
Microglia in Cancer Therapy-Related Cognitive Impairment. | Gibson EM, Monje M | Trends in neurosciences | 33674135 | Trends Neurosci | 2021 Jun |
The neurobiology of long COVID. | Monje M, Iwasaki A | Neuron | 36288726 | Neuron | 2022 Nov 2 |
Neuronal hyperexcitability drives central and peripheral nervous system tumor progression in models of neurofibromatosis-1. | Anastasaki C, Mo J, Chen JK, Chatterjee J, Pan Y, Scheaffer SM, Cobb O, Monje M, Le LQ, Gutmann DH | Nature communications | 35589737 | Nat Commun | 2022 May 19 |
GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas. | Majzner RG, Ramakrishna S, Yeom KW, Patel S, Chinnasamy H, Schultz LM, Richards RM, Jiang L, Barsan V, Mancusi R, Geraghty AC, Good Z, Mochizuki AY, Gillespie SM, Toland AMS, Mahdi J, Reschke A, Nie EH, Chau IJ, Rotiroti MC, Mount CW, Baggott C, Mavroukakis S, Egeler E, Moon J, Erickson C, Green S, Kunicki M, Fujimoto M, Ehlinger Z, Reynolds W, Kurra S, Warren KE, Prabhu S, Vogel H, Rasmussen L, Cornell TT, Partap S, Fisher PG, Campen CJ, Filbin MG, Grant G, Sahaf B, Davis KL, Feldman SA, Mackall CL, Monje M | Nature | 35130560 | Nature | 2022 Mar |
Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain. | Fernández-Castañeda A, Lu P, Geraghty AC, Song E, Lee MH, Wood J, Yalçın B, Taylor KR, Dutton S, Acosta-Alvarez L, Ni L, Contreras-Esquivel D, Gehlhausen JR, Klein J, Lucas C, Mao T, Silva J, Peña-Hernández MA, Tabachnikova A, Takahashi T, Tabacof L, Tosto-Mancuso J, Breyman E, Kontorovich A, McCarthy D, Quezado M, Hefti M, Perl D, Folkerth R, Putrino D, Nath A, Iwasaki A, Monje M | bioRxiv : the preprint server for biology | 35043113 | bioRxiv | 2022 Jan 10 |
The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location. | Liu I, Jiang L, Samuelsson ER, Marco Salas S, Beck A, Hack OA, Jeong D, Shaw ML, Englinger B, LaBelle J, Mire HM, Madlener S, Mayr L, Quezada MA, Trissal M, Panditharatna E, Ernst KJ, Vogelzang J, Gatesman TA, Halbert ME, Palova H, Pokorna P, Sterba J, Slaby O, Geyeregger R, Diaz A, Findlay IJ, Dun MD, Resnick A, Suvà ML, Jones DTW, Agnihotri S, Svedlund J, Koschmann C, Haberler C, Czech T, Slavc I, Cotter JA, Ligon KL, Alexandrescu S, Yung WKA, Arrillaga-Romany I, Gojo J, Monje M, Nilsson M, Filbin MG | Nature genetics | 36471067 | Nat Genet | 2022 Dec |
The neuroscience of cancer. | Mancusi R, Monje M | Nature | 37316719 | Nature | 2023 Jun |
Haploinsufficiency of NFKBIA reshapes the epigenome antipodal to the IDH mutation and imparts disease fate in diffuse gliomas. | Bredel M, Espinosa L, Kim H, Scholtens DM, McElroy JP, Rajbhandari R, Meng W, Kollmeyer TM, Malta TM, Quezada MA, Harsh GR, Lobo-Jarne T, Solé L, Merati A, Nagaraja S, Nair S, White JJ, Thudi NK, Fleming JL, Webb A, Natsume A, Ogawa S, Weber RG, Bertran J, Haque SJ, Hentschel B, Miller CR, Furnari FB, Chan TA, Grosu AL, Weller M, Barnholtz-Sloan JS, Monje M, Noushmehr H, Jenkins RB, Rogers CL, MacDonald DR, Pugh SL, Chakravarti A | Cell reports. Medicine | 37343523 | Cell Rep Med | 2023 Jun 20 |
Tumor inflammation-associated neurotoxicity. | Mahdi J, Dietrich J, Straathof K, Roddie C, Scott BJ, Davidson TB, Prolo LM, Batchelor TT, Campen CJ, Davis KL, Gust J, Lim M, Majzner RG, Park JR, Partap S, Ramakrishna S, Richards R, Schultz L, Vitanza NA, Wang LD, Mackall CL, Monje M | Nature medicine | 37024595 | Nat Med | 2023 Apr |
Cancer neuroscience: State of the field, emerging directions. | Winkler F, Venkatesh HS, Amit M, Batchelor T, Demir IE, Deneen B, Gutmann DH, Hervey-Jumper S, Kuner T, Mabbott D, Platten M, Rolls A, Sloan EK, Wang TC, Wick W, Venkataramani V, Monje M | Cell | 37059069 | Cell | 2023 Apr 13 |
Neuron-oligodendroglial interactions in health and malignant disease. | Taylor KR, Monje M | Nature reviews. Neuroscience | 37857838 | Nat Rev Neurosci | 2023 Dec |
NF1 mutation drives neuronal activity-dependent initiation of optic glioma. | Pan Y, Hysinger JD, Barron T, Schindler NF, Cobb O, Guo X, Yalçın B, Anastasaki C, Mulinyawe SB, Ponnuswami A, Scheaffer S, Ma Y, Chang KC, Xia X, Toonen JA, Lennon JJ, Gibson EM, Huguenard JR, Liau LM, Goldberg JL, Monje M, Gutmann DH | Nature | 34040258 | Nature | 2021 Jun |
Monosynaptic tracing maps brain-wide afferent oligodendrocyte precursor cell connectivity. | Mount CW, Yalçın B, Cunliffe-Koehler K, Sundaresh S, Monje M | eLife | 31625910 | Elife | 2019 Oct 18 |
Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerability. | Drexler R, Khatri R, Sauvigny T, Mohme M, Maire CL, Ryba A, Zghaibeh Y, Dührsen L, Salviano-Silva A, Lamszus K, Westphal M, Gempt J, Wefers AK, Neumann J, Bode H, Hausmann F, Huber TB, Bonn S, Jütten K, Delev D, Weber KJ, Harter PN, Onken J, Vajkoczy P, Capper D, Wiestler B, Weller M, Snijder B, Buck A, Weiss T, Keough MB, Ni L, Monje M, Silverbush D, Hovestadt V, Suvà ML, Krishna S, Hervey-Jumper SL, Schüller U, Heiland DH, Hänzelmann S, Ricklefs FL | bioRxiv : the preprint server for biology | 37609137 | bioRxiv | 2023 Aug 7 |
Developmental origins and emerging therapeutic opportunities for childhood cancer. | Filbin M, Monje M | Nature medicine | 30842674 | Nat Med | 2019 Mar |
Maladaptive myelination promotes generalized epilepsy progression. | Knowles JK, Xu H, Soane C, Batra A, Saucedo T, Frost E, Tam LT, Fraga D, Ni L, Villar K, Talmi S, Huguenard JR, Monje M | Nature neuroscience | 35501379 | Nat Neurosci | 2022 May |
Immunotherapy-related cognitive impairment after CAR T cell therapy in mice. | Geraghty AC, Acosta-Alvarez L, Rotiroti M, Dutton S, O'Dea MR, Woo PJ, Xu H, Shamardani K, Mancusi R, Ni L, Mulinyawe SB, Kim WJ, Liddelow SA, Majzner RG, Monje M | bioRxiv : the preprint server for biology | 38798554 | bioRxiv | 2024 May 14 |
Nf1 mutation disrupts activity-dependent oligodendroglial plasticity and motor learning in mice. | Pan Y, Hysinger JD, Yalçın B, Lennon JJ, Byun YG, Raghavan P, Schindler NF, Anastasaki C, Chatterjee J, Ni L, Xu H, Malacon K, Jahan SM, Ivec AE, Aghoghovwia BE, Mount CW, Nagaraja S, Scheaffer S, Attardi LD, Gutmann DH, Monje M | Nature neuroscience | 38816530 | Nat Neurosci | 2024 Aug |
Emerging mechanistic underpinnings and therapeutic targets for chemotherapy-related cognitive impairment. | Gibson EM, Monje M | Current opinion in oncology | 31449084 | Curr Opin Oncol | 2019 Nov |
Transition to a mesenchymal state in neuroblastoma confers resistance to anti-GD2 antibody via reduced expression of ST8SIA1. | Mabe NW, Huang M, Dalton GN, Alexe G, Schaefer DA, Geraghty AC, Robichaud AL, Conway AS, Khalid D, Mader MM, Belk JA, Ross KN, Sheffer M, Linde MH, Ly N, Yao W, Rotiroti MC, Smith BAH, Wernig M, Bertozzi CR, Monje M, Mitsiades CS, Majeti R, Satpathy AT, Stegmaier K, Majzner RG | Nature cancer | 35817829 | Nat Cancer | 2022 Aug |
Neuron-Glial Interactions in Health and Brain Cancer. | Pan Y, Monje M | Advanced biology | 35957525 | Adv Biol (Weinh) | 2022 Sep |
Roadmap for the Emerging Field of Cancer Neuroscience. | Monje M, Borniger JC, D'Silva NJ, Deneen B, Dirks PB, Fattahi F, Frenette PS, Garzia L, Gutmann DH, Hanahan D, Hervey-Jumper SL, Hondermarck H, Hurov JB, Kepecs A, Knox SM, Lloyd AC, Magnon C, Saloman JL, Segal RA, Sloan EK, Sun X, Taylor MD, Tracey KJ, Trotman LC, Tuveson DA, Wang TC, White RA, Winkler F | Cell | 32302564 | Cell | 2020 Apr 16 |
A light-gated transcriptional recorder for detecting cell-cell contacts. | Cho KF, Gillespie SM, Kalogriopoulos NA, Quezada MA, Jacko M, Monje M, Ting AY | eLife | 35311648 | Elife | 2022 Mar 21 |
Remote neuronal activity drives glioma progression through SEMA4F. | Huang-Hobbs E, Cheng YT, Ko Y, Luna-Figueroa E, Lozzi B, Taylor KR, McDonald M, He P, Chen HC, Yang Y, Maleki E, Lee ZF, Murali S, Williamson MR, Choi D, Curry R, Bayley J, Woo J, Jalali A, Monje M, Noebels JL, Harmanci AS, Rao G, Deneen B | Nature | 37380778 | Nature | 2023 Jul |
Myelin plasticity in the ventral tegmental area is required for opioid reward. | Yalçın B, Pomrenze MB, Malacon K, Drexler R, Rogers AE, Shamardani K, Chau IJ, Taylor KR, Ni L, Contreras-Esquivel D, Malenka RC, Monje M | Nature | 38839962 | Nature | 2024 Jun |
Tle4 controls both developmental acquisition and early post-natal maturation of corticothalamic projection neuron identity. | Galazo MJ, Sweetser DA, Macklis JD | Cell reports | 37561632 | Cell Rep | 2023 Aug 29 |
Limitations of fluorescent timer protein maturation kinetics to isolate transcriptionally synchronized cortically differentiating human pluripotent stem cells. | Peter M, Shipman S, Macklis JD | bioRxiv : the preprint server for biology | 37609140 | bioRxiv | 2023 Aug 26 |
Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors. | Ozkan A, Padmanabhan HK, Shipman SL, Azim E, Kumar P, Sadegh C, Basak AN, Macklis JD | bioRxiv : the preprint server for biology | 38712174 | bioRxiv | 2024 Apr 23 |
Corticospinal neuron subpopulation-specific developmental genes prospectively indicate mature segmentally specific axon projection targeting. | Sahni V, Shnider SJ, Jabaudon D, Song JHT, Itoh Y, Greig LC, Macklis JD | Cell reports | 34686320 | Cell Rep | 2021 Oct 19 |
Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations. | Itoh Y, Sahni V, Shnider SJ, McKee H, Macklis JD | Cell reports | 36934325 | Cell Rep | 2023 Mar 28 |
Dynamic subtype- and context-specific subcellular RNA regulation in growth cones of developing neurons of the cerebral cortex. | Veeraraghavan P, Engmann AK, Hatch JJ, Itoh Y, Nguyen D, Addison T, Macklis JD | bioRxiv : the preprint server for biology | 38328182 | bioRxiv | 2024 Jan 23 |
Symmetry in levels of axon-axon homophilic adhesion establishes topography in the corpus callosum and development of connectivity between brain hemispheres. | Poulopoulos A, Davis P, Brandenburg C, Itoh Y, Galazo MJ, Greig LC, Romanowski AJ, Budnik B, Macklis JD | bioRxiv : the preprint server for biology | 38585721 | bioRxiv | 2024 Mar 31 |
BEAM: A combinatorial recombinase toolbox for binary gene expression and mosaic genetic analysis. | Greig LC, Woodworth MB, Poulopoulos A, Lim S, Macklis JD | Cell reports | 39159043 | Cell Rep | 2024 Aug 27 |
Crim1 and Kelch-like 14 exert complementary dual-directional developmental control over segmentally specific corticospinal axon projection targeting. | Sahni V, Itoh Y, Shnider SJ, Macklis JD | Cell reports | 34686337 | Cell Rep | 2021 Oct 19 |
Limitations of fluorescent timer protein maturation kinetics to isolate transcriptionally synchronized human neural progenitor cells. | Peter M, Shipman S, Heo J, Macklis JD | iScience | 38784012 | iScience | 2024 Jun 21 |
Cortical projection neurons with distinct axonal connectivity employ ribosomal complexes with distinct protein compositions. | Tran TP, Budnik B, Froberg JE, Macklis JD | bioRxiv : the preprint server for biology | 39763931 | bioRxiv | 2024 Dec 28 |
Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex. | Poulopoulos A, Murphy AJ, Ozkan A, Davis P, Hatch J, Kirchner R, Macklis JD | Nature | 30626971 | Nature | 2019 Jan |
Neuronal subtype-specific growth cone and soma purification from mammalian CNS via fractionation and fluorescent sorting for subcellular analyses and spatial mapping of local transcriptomes and proteomes. | Engmann AK, Hatch JJ, Nanda P, Veeraraghavan P, Ozkan A, Poulopoulos A, Murphy AJ, Macklis JD | Nature protocols | 35022617 | Nat Protoc | 2022 Feb |
An evolutionarily acquired microRNA shapes development of mammalian cortical projections. | Diaz JL, Siththanandan VB, Lu V, Gonzalez-Nava N, Pasquina L, MacDonald JL, Woodworth MB, Ozkan A, Nair R, He Z, Sahni V, Sarnow P, Palmer TD, Macklis JD, Tharin S | Proceedings of the National Academy of Sciences of the United States of America | 33139574 | Proc Natl Acad Sci U S A | 2020 Nov 17 |
Cbln1 Directs Axon Targeting by Corticospinal Neurons Specifically toward Thoraco-Lumbar Spinal Cord. | Song JHT, Ruven C, Patel P, Ding F, Macklis JD, Sahni V | The Journal of neuroscience : the official journal of the Society for Neuroscience | 36823038 | J Neurosci | 2023 Mar 15 |
Development of nanoRibo-seq enables study of regulated translation by cortical neuron subtypes, showing uORF translation in synaptic-axonal genes. | Froberg JE, Durak O, Macklis JD | Cell reports | 37624698 | Cell Rep | 2023 Sep 26 |
In vivo molecular imaging for immunotherapy using ultra-bright near-infrared-IIb rare-earth nanoparticles. | Zhong Y, Ma Z, Wang F, Wang X, Yang Y, Liu Y, Zhao X, Li J, Du H, Zhang M, Cui Q, Zhu S, Sun Q, Wan H, Tian Y, Liu Q, Wang W, Garcia KC, Dai H | Nature biotechnology | 31570897 | Nat Biotechnol | 2019 Nov |
Cross-Link-Functionalized Nanoparticles for Rapid Excretion in Nanotheranostic Applications. | Ma Z, Wang F, Zhong Y, Salazar F, Li J, Zhang M, Ren F, Wu AM, Dai H | Angewandte Chemie (Weinheim an der Bergstrasse, Germany) | 34334834 | Angew Chem Weinheim Bergstr Ger | 2020 Nov 9 |
3D NIR-II Molecular Imaging Distinguishes Targeted Organs with High-Performance NIR-II Bioconjugates. | Zhu S, Herraiz S, Yue J, Zhang M, Wan H, Yang Q, Ma Z, Wang Y, He J, Antaris AL, Zhong Y, Diao S, Feng Y, Zhou Y, Yu K, Hong G, Liang Y, Hsueh AJ, Dai H | Advanced materials (Deerfield Beach, Fla.) | 29446156 | Adv Mater | 2018 Mar |
Boosting the down-shifting luminescence of rare-earth nanocrystals for biological imaging beyond 1500 nm. | Zhong Y, Ma Z, Zhu S, Yue J, Zhang M, Antaris AL, Yuan J, Cui R, Wan H, Zhou Y, Wang W, Huang NF, Luo J, Hu Z, Dai H | Nature communications | 28963467 | Nat Commun | 2017 Sep 29 |
Shortwave-infrared-light-emitting probes for the in vivo tracking of cancer vaccines and the elicited immune responses. | Ren F, Wang F, Baghdasaryan A, Li Y, Liu H, Hsu R, Wang C, Li J, Zhong Y, Salazar F, Xu C, Jiang Y, Ma Z, Zhu G, Zhao X, Wong KK, Willis R, Christopher Garcia K, Wu A, Mellins E, Dai H | Nature biomedical engineering | 37620621 | Nat Biomed Eng | 2024 Jun |
Bright quantum dots emitting at ∼1,600 nm in the NIR-IIb window for deep tissue fluorescence imaging. | Zhang M, Yue J, Cui R, Ma Z, Wan H, Wang F, Zhu S, Zhou Y, Kuang Y, Zhong Y, Pang DW, Dai H | Proceedings of the National Academy of Sciences of the United States of America | 29891702 | Proc Natl Acad Sci U S A | 2018 Jun 26 |
Molecular Cancer Imaging in the Second Near-Infrared Window Using a Renal-Excreted NIR-II Fluorophore-Peptide Probe. | Wang W, Ma Z, Zhu S, Wan H, Yue J, Ma H, Ma R, Yang Q, Wang Z, Li Q, Qian Y, Yue C, Wang Y, Fan L, Zhong Y, Zhou Y, Gao H, Ruan J, Hu Z, Liang Y, Dai H | Advanced materials (Deerfield Beach, Fla.) | 29682821 | Adv Mater | 2018 May |
Developing a Bright NIR-II Fluorophore with Fast Renal Excretion and Its Application in Molecular Imaging of Immune Checkpoint PD-L1. | Wan H, Ma H, Zhu S, Wang F, Tian Y, Ma R, Yang Q, Hu Z, Zhu T, Wang W, Ma Z, Zhang M, Zhong Y, Sun H, Liang Y, Dai H | Advanced functional materials | 31832053 | Adv Funct Mater | 2018 Dec 12 |
Near-Infrared IIb Fluorescence Imaging of Vascular Regeneration with Dynamic Tissue Perfusion Measurement and High Spatial Resolution. | Ma Z, Zhang M, Yue J, Alcazar C, Zhong Y, Doyle TC, Dai H, Huang NF | Advanced functional materials | 31327961 | Adv Funct Mater | 2018 Sep 5 |
Phosphorylcholine-conjugated gold-molecular clusters improve signal for Lymph Node NIR-II fluorescence imaging in preclinical cancer models. | Baghdasaryan A, Wang F, Ren F, Ma Z, Li J, Zhou X, Grigoryan L, Xu C, Dai H | Nature communications | 36153336 | Nat Commun | 2022 Sep 24 |
A SARS-CoV-2 vaccine on an NIR-II/SWIR emitting nanoparticle platform. | Jiang Y, Sanyal M, Hussein NA, Baghdasaryan A, Zhang M, Wang F, Ren F, Li J, Zhu G, Meng Y, Adamska JZ, Mellins E, Dai H | Science advances | 39919189 | Sci Adv | 2025 Feb 7 |
Rational Design of Molecular Fluorophores for Biological Imaging in the NIR-II Window. | Yang Q, Ma Z, Wang H, Zhou B, Zhu S, Zhong Y, Wang J, Wan H, Antaris A, Ma R, Zhang X, Yang J, Zhang X, Sun H, Liu W, Liang Y, Dai H | Advanced materials (Deerfield Beach, Fla.) | 28117499 | Adv Mater | 2017 Mar |
A high quantum yield molecule-protein complex fluorophore for near-infrared II imaging. | Antaris AL, Chen H, Diao S, Ma Z, Zhang Z, Zhu S, Wang J, Lozano AX, Fan Q, Chew L, Zhu M, Cheng K, Hong X, Dai H, Cheng Z | Nature communications | 28524850 | Nat Commun | 2017 May 19 |
A mini-review on rare-earth down-conversion nanoparticles for NIR-II imaging of biological systems. | Zhong Y, Dai H | Nano research | 34336144 | Nano Res | 2020 May |
High-precision tumor resection down to few-cell level guided by NIR-IIb molecular fluorescence imaging. | Wang F, Qu L, Ren F, Baghdasaryan A, Jiang Y, Hsu R, Liang P, Li J, Zhu G, Ma Z, Dai H | Proceedings of the National Academy of Sciences of the United States of America | 35380898 | Proc Natl Acad Sci U S A | 2022 Apr 12 |
A theranostic agent for cancer therapy and imaging in the second near-infrared window. | Ma Z, Wan H, Wang W, Zhang X, Uno T, Yang Q, Yue J, Gao H, Zhong Y, Tian Y, Sun Q, Liang Y, Dai H | Nano research | 31832124 | Nano Res | 2019 Feb |
In vivo non-invasive confocal fluorescence imaging beyond 1,700 nm using superconducting nanowire single-photon detectors. | Wang F, Ren F, Ma Z, Qu L, Gourgues R, Xu C, Baghdasaryan A, Li J, Zadeh IE, Los JWN, Fognini A, Qin-Dregely J, Dai H | Nature nanotechnology | 35606441 | Nat Nanotechnol | 2022 Jun |
Deep learning for in vivo near-infrared imaging. | Ma Z, Wang F, Wang W, Zhong Y, Dai H | Proceedings of the National Academy of Sciences of the United States of America | 33372162 | Proc Natl Acad Sci U S A | 2021 Jan 5 |
Live imaging of follicle stimulating hormone receptors in gonads and bones using near infrared II fluorophore. | Feng Y, Zhu S, Antaris AL, Chen H, Xiao Y, Lu X, Jiang L, Diao S, Yu K, Wang Y, Herraiz S, Yue J, Hong X, Hong G, Cheng Z, Dai H, Hsueh AJ | Chemical science | 28626555 | Chem Sci | 2017 May 1 |
In vivo NIR-II structured-illumination light-sheet microscopy. | Wang F, Ma Z, Zhong Y, Salazar F, Xu C, Ren F, Qu L, Wu AM, Dai H | Proceedings of the National Academy of Sciences of the United States of America | 33526701 | Proc Natl Acad Sci U S A | 2021 Feb 9 |
Near-Infrared-II Molecular Dyes for Cancer Imaging and Surgery. | Zhu S, Tian R, Antaris AL, Chen X, Dai H | Advanced materials (Deerfield Beach, Fla.) | 31025403 | Adv Mater | 2019 Jun |
Light-sheet microscopy in the near-infrared II window. | Wang F, Wan H, Ma Z, Zhong Y, Sun Q, Tian Y, Qu L, Du H, Zhang M, Li L, Ma H, Luo J, Liang Y, Li WJ, Hong G, Liu L, Dai H | Nature methods | 31086342 | Nat Methods | 2019 Jun |
A bright organic NIR-II nanofluorophore for three-dimensional imaging into biological tissues. | Wan H, Yue J, Zhu S, Uno T, Zhang X, Yang Q, Yu K, Hong G, Wang J, Li L, Ma Z, Gao H, Zhong Y, Su J, Antaris AL, Xia Y, Luo J, Liang Y, Dai H | Nature communications | 29563581 | Nat Commun | 2018 Mar 21 |
Molecular imaging in the second near-infrared window. | Wan H, Du H, Wang F, Dai H | Advanced functional materials | 31885529 | Adv Funct Mater | 2019 Jun 21 |
Intratumor injected gold molecular clusters for NIR-II imaging and cancer therapy. | Baghdasaryan A, Liu H, Ren F, Hsu R, Jiang Y, Wang F, Zhang M, Grigoryan L, Dai H | Proceedings of the National Academy of Sciences of the United States of America | 38261618 | Proc Natl Acad Sci U S A | 2024 Jan 30 |
Structure-Specific Cleavage of an RNA Repeat Expansion with a Dimeric Small Molecule Is Advantageous over Sequence-Specific Recognition by an Oligonucleotide. | Benhamou RI, Angelbello AJ, Andrews RJ, Wang ET, Moss WN, Disney MD | ACS chemical biology | 31927948 | ACS Chem Biol | 2020 Feb 21 |
Target-Directed Approaches for Screening Small Molecules against RNA Targets. | Haniff HS, Knerr L, Chen JL, Disney MD, Lightfoot HL | SLAS discovery : advancing life sciences R & D | 32419578 | SLAS Discov | 2020 Sep |
Using Genome Sequence to Enable the Design of Medicines and Chemical Probes. | Angelbello AJ, Chen JL, Childs-Disney JL, Zhang P, Wang ZF, Disney MD | Chemical reviews | 29322778 | Chem Rev | 2018 Feb 28 |
Precise small-molecule cleavage of an r(CUG) repeat expansion in a myotonic dystrophy mouse model. | Angelbello AJ, Rzuczek SG, Mckee KK, Chen JL, Olafson H, Cameron MD, Moss WN, Wang ET, Disney MD | Proceedings of the National Academy of Sciences of the United States of America | 30926669 | Proc Natl Acad Sci U S A | 2019 Apr 16 |
Targeted Degradation of a Hypoxia-Associated Non-coding RNA Enhances the Selectivity of a Small Molecule Interacting with RNA. | Costales MG, Suresh B, Vishnu K, Disney MD | Cell chemical biology | 31130520 | Cell Chem Biol | 2019 Aug 15 |
A Small Molecule that Binds an RNA Repeat Expansion Stimulates Its Decay via the Exosome Complex. | Angelbello AJ, Benhamou RI, Rzuczek SG, Choudhary S, Tang Z, Chen JL, Roy M, Wang KW, Yildirim I, Jun AS, Thornton CA, Disney MD | Cell chemical biology | 33157036 | Cell Chem Biol | 2021 Jan 21 |
Structural Features of Small Molecules Targeting the RNA Repeat Expansion That Causes Genetically Defined ALS/FTD. | Ursu A, Wang KW, Bush JA, Choudhary S, Chen JL, Baisden JT, Zhang YJ, Gendron TF, Petrucelli L, Yildirim I, Disney MD | ACS chemical biology | 33196168 | ACS Chem Biol | 2020 Dec 18 |
Targeting RNA with Small Molecules To Capture Opportunities at the Intersection of Chemistry, Biology, and Medicine. | Disney MD | Journal of the American Chemical Society | 30896935 | J Am Chem Soc | 2019 May 1 |
Small molecule targeting of RNA structures in neurological disorders. | Angelbello AJ, Chen JL, Disney MD | Annals of the New York Academy of Sciences | 30964958 | Ann N Y Acad Sci | 2020 Jul |
Fragment-Based Approaches to Identify RNA Binders. | Suresh BM, Taghavi A, Childs-Disney JL, Disney MD | Journal of medicinal chemistry | 37186875 | J Med Chem | 2023 May 25 |
Development of pharmacophore models for small molecules targeting RNA: Application to the RNA repeat expansion in myotonic dystrophy type 1. | Angelbello AJ, González ÀL, Rzuczek SG, Disney MD | Bioorganic & medicinal chemistry letters | 27839685 | Bioorg Med Chem Lett | 2016 Dec 1 |
Rational Design of Small Molecules Targeting Oncogenic Noncoding RNAs from Sequence. | Disney MD, Angelbello AJ | Accounts of chemical research | 27993012 | Acc Chem Res | 2016 Dec 20 |
Studying a Drug-like, RNA-Focused Small Molecule Library Identifies Compounds That Inhibit RNA Toxicity in Myotonic Dystrophy. | Rzuczek SG, Southern MR, Disney MD | ACS chemical biology | 26414664 | ACS Chem Biol | 2015 Dec 18 |
Small Molecule Recognition and Tools to Study Modulation of r(CGG)(exp) in Fragile X-Associated Tremor Ataxia Syndrome. | Yang WY, He F, Strack RL, Oh SY, Frazer M, Jaffrey SR, Todd PK, Disney MD | ACS chemical biology | 27276216 | ACS Chem Biol | 2016 Sep 16 |
The RNA encoding the microtubule-associated protein tau has extensive structure that affects its biology. | Chen JL, Moss WN, Spencer A, Zhang P, Childs-Disney JL, Disney MD | PloS one | 31291322 | PLoS One | 2019 |
A Toxic RNA Catalyzes the Cellular Synthesis of Its Own Inhibitor, Shunting It to Endogenous Decay Pathways. | Benhamou RI, Angelbello AJ, Wang ET, Disney MD | Cell chemical biology | 31981476 | Cell Chem Biol | 2020 Feb 20 |
A blood-brain penetrant RNA-targeted small molecule triggers elimination of r(G(4)C(2))(exp) in c9ALS/FTD via the nuclear RNA exosome. | Bush JA, Meyer SM, Fuerst R, Tong Y, Li Y, Benhamou RI, Aikawa H, Zanon PRA, Gibaut QMR, Angelbello AJ, Gendron TF, Zhang YJ, Petrucelli L, Heick Jensen T, Childs-Disney JL, Disney MD | Proceedings of the National Academy of Sciences of the United States of America | 36409902 | Proc Natl Acad Sci U S A | 2022 Nov 29 |
Small molecule alteration of RNA sequence in cells and animals. | Guan L, Luo Y, Ja WW, Disney MD | Bioorganic & medicinal chemistry letters | 29079470 | Bioorg Med Chem Lett | 2018 Sep 1 |
Precise small-molecule recognition of a toxic CUG RNA repeat expansion. | Rzuczek SG, Colgan LA, Nakai Y, Cameron MD, Furling D, Yasuda R, Disney MD | Nature chemical biology | 27941760 | Nat Chem Biol | 2017 Feb |
The Hairpin Form of r(G(4)C(2))(exp) in c9ALS/FTD Is Repeat-Associated Non-ATG Translated and a Target for Bioactive Small Molecules. | Wang ZF, Ursu A, Childs-Disney JL, Guertler R, Yang WY, Bernat V, Rzuczek SG, Fuerst R, Zhang YJ, Gendron TF, Yildirim I, Dwyer BG, Rice JE, Petrucelli L, Disney MD | Cell chemical biology | 30503283 | Cell Chem Biol | 2019 Feb 21 |
Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing. | Chen JL, Zhang P, Abe M, Aikawa H, Zhang L, Frank AJ, Zembryski T, Hubbs C, Park H, Withka J, Steppan C, Rogers L, Cabral S, Pettersson M, Wager TT, Fountain MA, Rumbaugh G, Childs-Disney JL, Disney MD | Journal of the American Chemical Society | 32364710 | J Am Chem Soc | 2020 May 13 |
Macrocyclization of a Ligand Targeting a Toxic RNA Dramatically Improves Potency. | Benhamou RI, Vezina-Dawod S, Choudhary S, Won Wang K, Meyer SM, Yildirim I, Disney MD | Chembiochem : a European journal of chemical biology | 32649032 | Chembiochem | 2020 Nov 16 |
A Toxic RNA Templates the Synthesis of Its Own Fluorogenic Inhibitor by Using a Bio-orthogonal Tetrazine Ligation in Cells and Tissues. | Angelbello AJ, Disney MD | ACS chemical biology | 32551539 | ACS Chem Biol | 2020 Jul 17 |
Gini Coefficients as a Single Value Metric to Define Chemical Probe Selectivity. | Ursu A, Childs-Disney JL, Angelbello AJ, Costales MG, Meyer SM, Disney MD | ACS chemical biology | 32568503 | ACS Chem Biol | 2020 Aug 21 |
Identifying and validating small molecules interacting with RNA (SMIRNAs). | Disney MD, Velagapudi SP, Li Y, Costales MG, Childs-Disney JL | Methods in enzymology | 31239057 | Methods Enzymol | 2019 |
Optimization of the Linker Domain in a Dimeric Compound that Degrades an r(CUG) Repeat Expansion in Cells. | Benhamou RI, Abe M, Choudhary S, Meyer SM, Angelbello AJ, Disney MD | Journal of medicinal chemistry | 32657583 | J Med Chem | 2020 Jul 23 |
Methods to identify and optimize small molecules interacting with RNA (SMIRNAs). | Ursu A, Vézina-Dawod S, Disney MD | Drug discovery today | 31356880 | Drug Discov Today | 2019 Oct |
Progress toward the development of the small molecule equivalent of small interfering RNA. | Disney MD, Suresh BM, Benhamou RI, Childs-Disney JL | Current opinion in chemical biology | 32036231 | Curr Opin Chem Biol | 2020 Jun |
Translation of the intrinsically disordered protein α-synuclein is inhibited by a small molecule targeting its structured mRNA. | Zhang P, Park HJ, Zhang J, Junn E, Andrews RJ, Velagapudi SP, Abegg D, Vishnu K, Costales MG, Childs-Disney JL, Adibekian A, Moss WN, Mouradian MM, Disney MD | Proceedings of the National Academy of Sciences of the United States of America | 31900363 | Proc Natl Acad Sci U S A | 2020 Jan 21 |
Small molecule recognition of disease-relevant RNA structures. | Meyer SM, Williams CC, Akahori Y, Tanaka T, Aikawa H, Tong Y, Childs-Disney JL, Disney MD | Chemical Society reviews | 32975549 | Chem Soc Rev | 2020 Oct 5 |
Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G(4)C(2)) repeat expansion in vitro and in vivo ALS models. | Bush JA, Aikawa H, Fuerst R, Li Y, Ursu A, Meyer SM, Benhamou RI, Chen JL, Khan T, Wagner-Griffin S, Van Meter MJ, Tong Y, Olafson H, McKee KK, Childs-Disney JL, Gendron TF, Zhang Y, Coyne AN, Wang ET, Yildirim I, Wang KW, Petrucelli L, Rothstein JD, Disney MD | Science translational medicine | 34705518 | Sci Transl Med | 2021 Oct 27 |
Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis. | Gendron TF, Chew J, Stankowski JN, Hayes LR, Zhang YJ, Prudencio M, Carlomagno Y, Daughrity LM, Jansen-West K, Perkerson EA, O'Raw A, Cook C, Pregent L, Belzil V, van Blitterswijk M, Tabassian LJ, Lee CW, Yue M, Tong J, Song Y, Castanedes-Casey M, Rousseau L, Phillips V, Dickson DW, Rademakers R, Fryer JD, Rush BK, Pedraza O, Caputo AM, Desaro P, Palmucci C, Robertson A, Heckman MG, Diehl NN, Wiggs E, Tierney M, Braun L, Farren J, Lacomis D, Ladha S, Fournier CN, McCluskey LF, Elman LB, Toledo JB, McBride JD, Tiloca C, Morelli C, Poletti B, Solca F, Prelle A, Wuu J, Jockel-Balsarotti J, Rigo F, Ambrose C, Datta A, Yang W, Raitcheva D, Antognetti G, McCampbell A, Van Swieten JC, Miller BL, Boxer AL, Brown RH, Bowser R, Miller TM, Trojanowski JQ, Grossman M, Berry JD, Hu WT, Ratti A, Traynor BJ, Disney MD, Benatar M, Silani V, Glass JD, Floeter MK, Rothstein JD, Boylan KB, Petrucelli L | Science translational medicine | 28356511 | Sci Transl Med | 2017 Mar 29 |
Structure and Dynamics of RNA Repeat Expansions That Cause Huntington's Disease and Myotonic Dystrophy Type 1. | Chen JL, VanEtten DM, Fountain MA, Yildirim I, Disney MD | Biochemistry | 28617590 | Biochemistry | 2017 Jul 11 |
Design of a bioactive small molecule that targets r(AUUCU) repeats in spinocerebellar ataxia 10. | Yang WY, Gao R, Southern M, Sarkar PS, Disney MD | Nature communications | 27248057 | Nat Commun | 2016 Jun 1 |
How We Think about Targeting RNA with Small Molecules. | Costales MG, Childs-Disney JL, Haniff HS, Disney MD | Journal of medicinal chemistry | 32212706 | J Med Chem | 2020 Sep 10 |
Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer. | Costales MG, Aikawa H, Li Y, Childs-Disney JL, Abegg D, Hoch DG, Pradeep Velagapudi S, Nakai Y, Khan T, Wang KW, Yildirim I, Adibekian A, Wang ET, Disney MD | Proceedings of the National Academy of Sciences of the United States of America | 31964809 | Proc Natl Acad Sci U S A | 2020 Feb 4 |
Drugging the RNA World. | Disney MD, Dwyer BG, Childs-Disney JL | Cold Spring Harbor perspectives in biology | 30385607 | Cold Spring Harb Perspect Biol | 2018 Nov 1 |
Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera. | Tong Y, Zhang P, Yang X, Liu X, Zhang J, Grudniewska M, Jung I, Abegg D, Liu J, Childs-Disney JL, Gibaut QMR, Haniff HS, Adibekian A, Mouradian MM, Disney MD | Proceedings of the National Academy of Sciences of the United States of America | 38181056 | Proc Natl Acad Sci U S A | 2024 Jan 9 |
Simultaneous dual-color fluorescence lifetime imaging with novel red-shifted fluorescent proteins. | Laviv T, Kim BB, Chu J, Lam AJ, Lin MZ, Yasuda R | Nature methods | 27798609 | Nat Methods | 2016 Dec |
CaMKII Autophosphorylation Is Necessary for Optimal Integration of Ca(2+) Signals during LTP Induction, but Not Maintenance. | Chang JY, Parra-Bueno P, Laviv T, Szatmari EM, Lee SR, Yasuda R | Neuron | 28521133 | Neuron | 2017 May 17 |
In Vivo Imaging of the Coupling between Neuronal and CREB Activity in the Mouse Brain. | Laviv T, Scholl B, Parra-Bueno P, Foote B, Zhang C, Yan L, Hayano Y, Chu J, Yasuda R | Neuron | 31883788 | Neuron | 2020 Mar 4 |
The NMDA receptor subunit GluN3A regulates synaptic activity-induced and myocyte enhancer factor 2C (MEF2C)-dependent transcription. | Chen LF, Lyons MR, Liu F, Green MV, Hedrick NG, Williams AB, Narayanan A, Yasuda R, West AE | The Journal of biological chemistry | 32393578 | J Biol Chem | 2020 Jun 19 |
Imaging ERK and PKA Activation in Single Dendritic Spines during Structural Plasticity. | Tang S, Yasuda R | Neuron | 28285819 | Neuron | 2017 Mar 22 |
Kinetics of Endogenous CaMKII Required for Synaptic Plasticity Revealed by Optogenetic Kinase Inhibitor. | Murakoshi H, Shin ME, Parra-Bueno P, Szatmari EM, Shibata ACE, Yasuda R | Neuron | 28318784 | Neuron | 2017 Apr 5 |
High-Throughput, High-Resolution Mapping of Protein Localization in Mammalian Brain by In Vivo Genome Editing. | Mikuni T, Nishiyama J, Sun Y, Kamasawa N, Yasuda R | Cell | 27180908 | Cell | 2016 Jun 16 |
An open-source tool for analysis and automatic identification of dendritic spines using machine learning. | Smirnov MS, Garrett TR, Yasuda R | PloS one | 29975722 | PLoS One | 2018 |
PKCα integrates spatiotemporally distinct Ca(2+) and autocrine BDNF signaling to facilitate synaptic plasticity. | Colgan LA, Hu M, Misler JA, Parra-Bueno P, Moran CM, Leitges M, Yasuda R | Nature neuroscience | 30013171 | Nat Neurosci | 2018 Aug |
Autocrine BDNF-TrkB signalling within a single dendritic spine. | Harward SC, Hedrick NG, Hall CE, Parra-Bueno P, Milner TA, Pan E, Laviv T, Hempstead BL, Yasuda R, McNamara JO | Nature | 27680698 | Nature | 2016 Oct 6 |
RGS14 Restricts Plasticity in Hippocampal CA2 by Limiting Postsynaptic Calcium Signaling. | Evans PR, Parra-Bueno P, Smirnov MS, Lustberg DJ, Dudek SM, Hepler JR, Yasuda R | eNeuro | 29911178 | eNeuro | 2018 May-Jun |
Rapid Ultrastructural Changes in the PSD and Surrounding Membrane after Induction of Structural LTP in Single Dendritic Spines. | Sun Y, Smirnov M, Kamasawa N, Yasuda R | The Journal of neuroscience : the official journal of the Society for Neuroscience | 34266899 | J Neurosci | 2021 Aug 18 |
Longitudinal Two-Photon Imaging of Dorsal Hippocampal CA1 in Live Mice. | Ulivi AF, Castello-Waldow TP, Weston G, Yan L, Yasuda R, Chen A, Attardo A | Journal of visualized experiments : JoVE | 31282875 | J Vis Exp | 2019 Jun 19 |
FRET Imaging of Rho GTPase Activity with Red Fluorescent Protein-Based FRET Pairs. | Bajar BT, Guan X, Lam A, Lin MZ, Yasuda R, Laviv T, Chu J | Methods in molecular biology (Clifton, N.J.) | 35147933 | Methods Mol Biol | 2022 |
Mechanisms of Ca(2+)/calmodulin-dependent kinase II activation in single dendritic spines. | Chang JY, Nakahata Y, Hayano Y, Yasuda R | Nature communications | 31239443 | Nat Commun | 2019 Jun 25 |
Reciprocal Activation within a Kinase-Effector Complex Underlying Persistence of Structural LTP. | Saneyoshi T, Matsuno H, Suzuki A, Murakoshi H, Hedrick NG, Agnello E, O'Connell R, Stratton MM, Yasuda R, Hayashi Y | Neuron | 31078368 | Neuron | 2019 Jun 19 |
Virus-Mediated Genome Editing via Homology-Directed Repair in Mitotic and Postmitotic Cells in Mammalian Brain. | Nishiyama J, Mikuni T, Yasuda R | Neuron | 29056297 | Neuron | 2017 Nov 15 |
Automated Remote Focusing, Drift Correction, and Photostimulation to Evaluate Structural Plasticity in Dendritic Spines. | Smirnov MS, Evans PR, Garrett TR, Yan L, Yasuda R | PloS one | 28114380 | PLoS One | 2017 |
Rho GTPase complementation underlies BDNF-dependent homo- and heterosynaptic plasticity. | Hedrick NG, Harward SC, Hall CE, Murakoshi H, McNamara JO, Yasuda R | Nature | 27680697 | Nature | 2016 Oct 6 |
Structure and mechanism of blood-brain-barrier lipid transporter MFSD2A. | Wood CAP, Zhang J, Aydin D, Xu Y, Andreone BJ, Langen UH, Dror RO, Gu C, Feng L | Nature | 34349262 | Nature | 2021 Aug |
Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier. | Ayloo S, Lazo CG, Sun S, Zhang W, Cui B, Gu C | Neuron | 35294899 | Neuron | 2022 May 18 |
Development and Cell Biology of the Blood-Brain Barrier. | Langen UH, Ayloo S, Gu C | Annual review of cell and developmental biology | 31299172 | Annu Rev Cell Dev Biol | 2019 Oct 6 |
Bridging barriers: a comparative look at the blood-brain barrier across organisms. | O'Brown NM, Pfau SJ, Gu C | Genes & development | 29692355 | Genes Dev | 2018 Apr 1 |
Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis. | Andreone BJ, Chow BW, Tata A, Lacoste B, Ben-Zvi A, Bullock K, Deik AA, Ginty DD, Clish CB, Gu C | Neuron | 28416077 | Neuron | 2017 May 3 |
Transcytosis at the blood-brain barrier. | Ayloo S, Gu C | Current opinion in neurobiology | 30708291 | Curr Opin Neurobiol | 2019 Aug |
Spreading depolarizations trigger caveolin-1-dependent endothelial transcytosis. | Sadeghian H, Lacoste B, Qin T, Toussay X, Rosa R, Oka F, Chung DY, Takizawa T, Gu C, Ayata C | Annals of neurology | 30014540 | Ann Neurol | 2018 Sep |
Temporal modulation of collective cell behavior controls vascular network topology. | Kur E, Kim J, Tata A, Comin CH, Harrington KI, Costa Lda F, Bentley K, Gu C | eLife | 26910011 | Elife | 2016 Feb 24 |
Gradual Suppression of Transcytosis Governs Functional Blood-Retinal Barrier Formation. | Chow BW, Gu C | Neuron | 28334606 | Neuron | 2017 Mar 22 |
Caveolae in CNS arterioles mediate neurovascular coupling. | Chow BW, Nuñez V, Kaplan L, Granger AJ, Bistrong K, Zucker HL, Kumar P, Sabatini BL, Gu C | Nature | 32076269 | Nature | 2020 Mar |
Characteristics of blood-brain barrier heterogeneity between brain regions revealed by profiling vascular and perivascular cells. | Pfau SJ, Langen UH, Fisher TM, Prakash I, Nagpurwala F, Lozoya RA, Lee WA, Wu Z, Gu C | Nature neuroscience | 39210068 | Nat Neurosci | 2024 Oct |
The molecular constituents of the blood-brain barrier. | Chow BW, Gu C | Trends in neurosciences | 26442694 | Trends Neurosci | 2015 Oct |
Control of cerebrovascular patterning by neural activity during postnatal development. | Lacoste B, Gu C | Mechanisms of development | 26116138 | Mech Dev | 2015 Nov |
Neuronal and vascular interactions. | Andreone BJ, Lacoste B, Gu C | Annual review of neuroscience | 25782970 | Annu Rev Neurosci | 2015 Jul 8 |
Suppression of transcytosis regulates zebrafish blood-brain barrier function. | O'Brown NM, Megason SG, Gu C | eLife | 31429822 | Elife | 2019 Aug 20 |
Neuronal regulation of the blood-brain barrier and neurovascular coupling. | Kaplan L, Chow BW, Gu C | Nature reviews. Neuroscience | 32636528 | Nat Rev Neurosci | 2020 Aug |
Protein-retention expansion microscopy of cells and tissues labeled using standard fluorescent proteins and antibodies. | Tillberg PW, Chen F, Piatkevich KD, Zhao Y, Yu CC, English BP, Gao L, Martorell A, Suk HJ, Yoshida F, DeGennaro EM, Roossien DH, Gong G, Seneviratne U, Tannenbaum SR, Desimone R, Cai D, Boyden ES | Nature biotechnology | 27376584 | Nat Biotechnol | 2016 Sep |
Physical principles for scalable neural recording. | Marblestone AH, Zamft BM, Maguire YG, Shapiro MG, Cybulski TR, Glaser JI, Amodei D, Stranges PB, Kalhor R, Dalrymple DA, Seo D, Alon E, Maharbiz MM, Carmena JM, Rabaey JM, Boyden ES, Church GM, Kording KP | Frontiers in computational neuroscience | 24187539 | Front Comput Neurosci | 2013 |
Spatial information in large-scale neural recordings. | Cybulski TR, Glaser JI, Marblestone AH, Zamft BM, Boyden ES, Church GM, Kording KP | Frontiers in computational neuroscience | 25653613 | Front Comput Neurosci | 2014 |
Green fluorescent genetically encoded calcium indicator based on calmodulin/M13-peptide from fungi. | Barykina NV, Subach OM, Piatkevich KD, Jung EE, Malyshev AY, Smirnov IV, Bogorodskiy AO, Borshchevskiy VI, Varizhuk AM, Pozmogova GE, Boyden ES, Anokhin KV, Enikolopov GN, Subach FV | PloS one | 28837632 | PLoS One | 2017 |
Optical imaging. Expansion microscopy. | Chen F, Tillberg PW, Boyden ES | Science (New York, N.Y.) | 25592419 | Science | 2015 Jan 30 |
Principles of designing interpretable optogenetic behavior experiments. | Allen BD, Singer AC, Boyden ES | Learning & memory (Cold Spring Harbor, N.Y.) | 25787711 | Learn Mem | 2015 Apr |
Closed-loop, ultraprecise, automated craniotomies. | Pak N, Siegle JH, Kinney JP, Denman DJ, Blanche TJ, Boyden ES | Journal of neurophysiology | 25855700 | J Neurophysiol | 2015 Jun 1 |
Population imaging of neural activity in awake behaving mice. | Piatkevich KD, Bensussen S, Tseng HA, Shroff SN, Lopez-Huerta VG, Park D, Jung EE, Shemesh OA, Straub C, Gritton HJ, Romano MF, Costa E, Sabatini BL, Fu Z, Boyden ES, Han X | Nature | 31597963 | Nature | 2019 Oct |
Precision Calcium Imaging of Dense Neural Populations via a Cell-Body-Targeted Calcium Indicator. | Shemesh OA, Linghu C, Piatkevich KD, Goodwin D, Celiker OT, Gritton HJ, Romano MF, Gao R, Yu CJ, Tseng HA, Bensussen S, Narayan S, Yang CT, Freifeld L, Siciliano CA, Gupta I, Wang J, Pak N, Yoon YG, Ullmann JFP, Guner-Ataman B, Noamany H, Sheinkopf ZR, Park WM, Asano S, Keating AE, Trimmer JS, Reimer J, Tolias AS, Bear MF, Tye KM, Han X, Ahrens MB, Boyden ES | Neuron | 32592656 | Neuron | 2020 Aug 5 |
3D nanofabrication by volumetric deposition and controlled shrinkage of patterned scaffolds. | Oran D, Rodriques SG, Gao R, Asano S, Skylar-Scott MA, Chen F, Tillberg PW, Marblestone AH, Boyden ES | Science (New York, N.Y.) | 30545883 | Science | 2018 Dec 14 |
A novel flexible cuff-like microelectrode for dual purpose, acute and chronic electrical interfacing with the mouse cervical vagus nerve. | Caravaca AS, Tsaava T, Goldman L, Silverman H, Riggott G, Chavan SS, Bouton C, Tracey KJ, Desimone R, Boyden ES, Sohal HS, Olofsson PS | Journal of neural engineering | 28628030 | J Neural Eng | 2017 Dec |
Revealing nanostructures in brain tissue via protein decrowding by iterative expansion microscopy. | Sarkar D, Kang J, Wassie AT, Schroeder ME, Peng Z, Tarr TB, Tang AH, Niederst ED, Young JZ, Su H, Park D, Yin P, Tsai LH, Blanpied TA, Boyden ES | Nature biomedical engineering | 36038771 | Nat Biomed Eng | 2022 Sep |
Dense, Continuous Membrane Labeling and Expansion Microscopy Visualization of Ultrastructure in Tissues. | Shin TW, Wang H, Zhang C, An B, Lu Y, Zhang E, Lu X, Karagiannis ED, Kang JS, Emenari A, Symvoulidis P, Asano S, Lin L, Costa EK, IMAXT Grand Challenge Consortium, Marblestone AH, Kasthuri N, Tsai LH, Boyden ES | bioRxiv : the preprint server for biology | 38496681 | bioRxiv | 2024 Mar 8 |
Designing tools for assumption-proof brain mapping. | Marblestone AH, Boyden ES | Neuron | 25233303 | Neuron | 2014 Sep 17 |
Assembly and operation of the autopatcher for automated intracellular neural recording in vivo. | Kodandaramaiah SB, Holst GL, Wickersham IR, Singer AC, Franzesi GT, McKinnon ML, Forest CR, Boyden ES | Nature protocols | 26938115 | Nat Protoc | 2016 Apr |
Hybrid Microscopy: Enabling Inexpensive High-Performance Imaging through Combined Physical and Optical Magnifications. | Zhang YS, Chang JB, Alvarez MM, Trujillo-de Santiago G, Aleman J, Batzaya B, Krishnadoss V, Ramanujam AA, Kazemzadeh-Narbat M, Chen F, Tillberg PW, Dokmeci MR, Boyden ES, Khademhosseini A | Scientific reports | 26975883 | Sci Rep | 2016 Mar 15 |
Automated in vivo patch-clamp evaluation of extracellular multielectrode array spike recording capability. | Allen BD, Moore-Kochlacs C, Bernstein JG, Kinney JP, Scholvin J, Seoane LF, Chronopoulos C, Lamantia C, Kodandaramaiah SB, Tegmark M, Boyden ES | Journal of neurophysiology | 29995597 | J Neurophysiol | 2018 Nov 1 |
Sonofragmentation of Ultrathin 1D Nanomaterials. | Gao R, Gupta I, Boyden ES | Particle & particle systems characterization : measurement and description of particle properties and behavior in powders and other disperse systems | 28804214 | Part Part Syst Charact | 2017 Jan |
Closed-Loop Real-Time Imaging Enables Fully Automated Cell-Targeted Patch-Clamp Neural Recording In Vivo. | Suk HJ, van Welie I, Kodandaramaiah SB, Allen B, Forest CR, Boyden ES | Neuron | 28858614 | Neuron | 2017 Aug 30 |
Nanoscale imaging of clinical specimens using pathology-optimized expansion microscopy. | Zhao Y, Bucur O, Irshad H, Chen F, Weins A, Stancu AL, Oh EY, DiStasio M, Torous V, Glass B, Stillman IE, Schnitt SJ, Beck AH, Boyden ES | Nature biotechnology | 28714966 | Nat Biotechnol | 2017 Aug |
Close-Packed Silicon Microelectrodes for Scalable Spatially Oversampled Neural Recording. | Scholvin J, Kinney JP, Bernstein JG, Moore-Kochlacs C, Kopell N, Fonstad CG, Boyden ES | IEEE transactions on bio-medical engineering | 26699649 | IEEE Trans Biomed Eng | 2016 Jan |
Engineering genetic circuit interactions within and between synthetic minimal cells. | Adamala KP, Martin-Alarcon DA, Guthrie-Honea KR, Boyden ES | Nature chemistry | 28430194 | Nat Chem | 2017 May |
A robotic multidimensional directed evolution approach applied to fluorescent voltage reporters. | Piatkevich KD, Jung EE, Straub C, Linghu C, Park D, Suk HJ, Hochbaum DR, Goodwin D, Pnevmatikakis E, Pak N, Kawashima T, Yang CT, Rhoades JL, Shemesh O, Asano S, Yoon YG, Freifeld L, Saulnier JL, Riegler C, Engert F, Hughes T, Drobizhev M, Szabo B, Ahrens MB, Flavell SW, Sabatini BL, Boyden ES | Nature chemical biology | 29483642 | Nat Chem Biol | 2018 Apr |
Nanoscale imaging of RNA with expansion microscopy. | Chen F, Wassie AT, Cote AJ, Sinha A, Alon S, Asano S, Daugharthy ER, Chang JB, Marblestone A, Church GM, Raj A, Boyden ES | Nature methods | 27376770 | Nat Methods | 2016 Aug |
Simultaneous whole-animal 3D imaging of neuronal activity using light-field microscopy. | Prevedel R, Yoon YG, Hoffmann M, Pak N, Wetzstein G, Kato S, Schrödel T, Raskar R, Zimmer M, Boyden ES, Vaziri A | Nature methods | 24836920 | Nat Methods | 2014 Jul |
Gamma frequency entrainment attenuates amyloid load and modifies microglia. | Iaccarino HF, Singer AC, Martorell AJ, Rudenko A, Gao F, Gillingham TZ, Mathys H, Seo J, Kritskiy O, Abdurrob F, Adaikkan C, Canter RG, Rueda R, Brown EN, Boyden ES, Tsai LH | Nature | 27929004 | Nature | 2016 Dec 7 |
Expansion microscopy: principles and uses in biological research. | Wassie AT, Zhao Y, Boyden ES | Nature methods | 30573813 | Nat Methods | 2019 Jan |
A theoretical analysis of single molecule protein sequencing via weak binding spectra. | Rodriques SG, Marblestone AH, Boyden ES | PloS one | 30921350 | PLoS One | 2019 |
Spatial Multiplexing of Fluorescent Reporters for Imaging Signaling Network Dynamics. | Linghu C, Johnson SL, Valdes PA, Shemesh OA, Park WM, Park D, Piatkevich KD, Wassie AT, Liu Y, An B, Barnes SA, Celiker OT, Yao CC, Yu CJ, Wang R, Adamala KP, Bear MF, Keating AE, Boyden ES | Cell | 33232692 | Cell | 2020 Dec 10 |
RNA timestamps identify the age of single molecules in RNA sequencing. | Rodriques SG, Chen LM, Liu S, Zhong ED, Scherrer JR, Boyden ES, Chen F | Nature biotechnology | 33077959 | Nat Biotechnol | 2021 Mar |
Expansion Microscopy: Protocols for Imaging Proteins and RNA in Cells and Tissues. | Asano SM, Gao R, Wassie AT, Tillberg PW, Chen F, Boyden ES | Current protocols in cell biology | 30070431 | Curr Protoc Cell Biol | 2018 Sep |
Temporally precise single-cell-resolution optogenetics. | Shemesh OA, Tanese D, Zampini V, Linghu C, Piatkevich K, Ronzitti E, Papagiakoumou E, Boyden ES, Emiliani V | Nature neuroscience | 29184208 | Nat Neurosci | 2017 Dec |
In situ genome sequencing resolves DNA sequence and structure in intact biological samples. | Payne AC, Chiang ZD, Reginato PL, Mangiameli SM, Murray EM, Yao CC, Markoulaki S, Earl AS, Labade AS, Jaenisch R, Church GM, Boyden ES, Buenrostro JD, Chen F | Science (New York, N.Y.) | 33384301 | Science | 2021 Feb 26 |
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Distilling complexity to advance cardiac tissue engineering. | Ogle BM, Bursac N, Domian I, Huang NF, Menasché P, Murry CE, Pruitt B, Radisic M, Wu JC, Wu SM, Zhang J, Zimmermann WH, Vunjak-Novakovic G | Science translational medicine | 27280684 | Sci Transl Med | 2016 Jun 8 |
Tissue Engineering of 3D Organotypic Microtissues by Acoustic Assembly. | Zhu Y, Serpooshan V, Wu S, Demirci U, Chen P, Güven S | Methods in molecular biology (Clifton, N.J.) | 28921421 | Methods Mol Biol | 2019 |
Contractile force generation by 3D hiPSC-derived cardiac tissues is enhanced by rapid establishment of cellular interconnection in matrix with muscle-mimicking stiffness. | Lee S, Serpooshan V, Tong X, Venkatraman S, Lee M, Lee J, Chirikian O, Wu JC, Wu SM, Yang F | Biomaterials | 28384492 | Biomaterials | 2017 Jul |
Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis. | Hinson JT, Chopra A, Lowe A, Sheng CC, Gupta RM, Kuppusamy R, O'Sullivan J, Rowe G, Wakimoto H, Gorham J, Burke MA, Zhang K, Musunuru K, Gerszten RE, Wu SM, Chen CS, Seidman JG, Seidman CE | Cell reports | 28009297 | Cell Rep | 2016 Dec 20 |
Identification of a hybrid myocardial zone in the mammalian heart after birth. | Tian X, Li Y, He L, Zhang H, Huang X, Liu Q, Pu W, Zhang L, Li Y, Zhao H, Wang Z, Zhu J, Nie Y, Hu S, Sedmera D, Zhong TP, Yu Y, Zhang L, Yan Y, Qiao Z, Wang QD, Wu SM, Pu WT, Anderson RH, Zhou B | Nature communications | 28729659 | Nat Commun | 2017 Jul 20 |
In Vivo Rescue of the Hematopoietic Niche By Pluripotent Stem Cell Complementation of Defective Osteoblast Compartments. | Chubb R, Oh J, Riley AK, Kimura T, Wu SM, Wu JY | Stem cells (Dayton, Ohio) | 28741855 | Stem Cells | 2017 Oct |
Single cell expression analysis reveals anatomical and cell cycle-dependent transcriptional shifts during heart development. | Li G, Tian L, Goodyer W, Kort EJ, Buikema JW, Xu A, Wu JC, Jovinge S, Wu SM | Development (Cambridge, England) | 31142541 | Development | 2019 Jun 14 |
Fetal Mammalian Heart Generates a Robust Compensatory Response to Cell Loss. | Sturzu AC, Rajarajan K, Passer D, Plonowska K, Riley A, Tan TC, Sharma A, Xu AF, Engels MC, Feistritzer R, Li G, Selig MK, Geissler R, Robertson KD, Scherrer-Crosbie M, Domian IJ, Wu SM | Circulation | 25995316 | Circulation | 2015 Jul 14 |
Harnessing the Induction of Cardiomyocyte Proliferation for Cardiac Regenerative Medicine. | Sharma A, Zhang Y, Wu SM | Current treatment options in cardiovascular medicine | 26324824 | Curr Treat Options Cardiovasc Med | 2015 Oct |
The relationship between cardiac endothelium and fibroblasts: it's complicated. | Karra R, Walter AO, Wu SM | The Journal of clinical investigation | 28650344 | J Clin Invest | 2017 Aug 1 |
Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution. | Goodyer WR, Beyersdorf BM, Paik DT, Tian L, Li G, Buikema JW, Chirikian O, Choi S, Venkatraman S, Adams EL, Tessier-Lavigne M, Wu JC, Wu SM | Circulation research | 31284824 | Circ Res | 2019 Aug 2 |
Untangling the Biology of Genetic Cardiomyopathies with Pluripotent Stem Cell Disease Models. | Buikema JW, Wu SM | Current cardiology reports | 28315121 | Curr Cardiol Rep | 2017 Apr |
Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons. | Chuang W, Sharma A, Shukla P, Li G, Mall M, Rajarajan K, Abilez OJ, Hamaguchi R, Wu JC, Wernig M, Wu SM | Scientific reports | 28327614 | Sci Rep | 2017 Mar 22 |
Cardiac Regeneration: Lessons From Development. | Galdos FX, Guo Y, Paige SL, VanDusen NJ, Wu SM, Pu WT | Circulation research | 28302741 | Circ Res | 2017 Mar 17 |
Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function. | Wnorowski A, Sharma A, Chen H, Wu H, Shao NY, Sayed N, Liu C, Countryman S, Stodieck LS, Rubins KH, Wu SM, Lee PHU, Wu JC | Stem cell reports | 31708475 | Stem Cell Reports | 2019 Dec 10 |
Prometheus Unbound in Ya(p) Heart. | Buikema JW, Wu SM | Developmental cell | 30913402 | Dev Cell | 2019 Mar 25 |
Genome Editing Redefines Precision Medicine in the Cardiovascular Field. | Dzilic E, Lahm H, Dreßen M, Deutsch MA, Lange R, Wu SM, Krane M, Doppler SA | Stem cells international | 29731778 | Stem Cells Int | 2018 |
Nkx2.5+ Cardiomyoblasts Contribute to Cardiomyogenesis in the Neonatal Heart. | Serpooshan V, Liu YH, Buikema JW, Galdos FX, Chirikian O, Paige S, Venkatraman S, Kumar A, Rawnsley DR, Huang X, Pijnappels DA, Wu SM | Scientific reports | 28974782 | Sci Rep | 2017 Oct 3 |
Transcriptomic Profiling Maps Anatomically Patterned Subpopulations among Single Embryonic Cardiac Cells. | Li G, Xu A, Sim S, Priest JR, Tian X, Khan T, Quertermous T, Zhou B, Tsao PS, Quake SR, Wu SM | Developmental cell | 27840109 | Dev Cell | 2016 Nov 21 |
In vivo visualization and molecular targeting of the cardiac conduction system. | Goodyer WR, Beyersdorf BM, Duan L, van den Berg NS, Mantri S, Galdos FX, Puluca N, Buikema JW, Lee S, Salmi D, Robinson ER, Rogalla S, Cogan DP, Khosla C, Rosenthal EL, Wu SM | The Journal of clinical investigation | 35951416 | J Clin Invest | 2022 Oct 17 |
Massive expansion and cryopreservation of functional human induced pluripotent stem cell-derived cardiomyocytes. | Maas RGC, Lee S, Harakalova M, Snijders Blok CJB, Goodyer WR, Hjortnaes J, Doevendans PAFM, Van Laake LW, van der Velden J, Asselbergs FW, Wu JC, Sluijter JPG, Wu SM, Buikema JW | STAR protocols | 33615277 | STAR Protoc | 2021 Mar 19 |
Cardiovascular Risks in Patients with COVID-19: Potential Mechanisms and Areas of Uncertainty. | Cheng P, Zhu H, Witteles RM, Wu JC, Quertermous T, Wu SM, Rhee JW | Current cardiology reports | 32350632 | Curr Cardiol Rep | 2020 Apr 29 |
Intrinsic Endocardial Defects Contribute to Hypoplastic Left Heart Syndrome. | Miao Y, Tian L, Martin M, Paige SL, Galdos FX, Li J, Klein A, Zhang H, Ma N, Wei Y, Stewart M, Lee S, Moonen JR, Zhang B, Grossfeld P, Mital S, Chitayat D, Wu JC, Rabinovitch M, Nelson TJ, Nie S, Wu SM, Gu M | Cell stem cell | 32810435 | Cell Stem Cell | 2020 Oct 1 |
Integrin Based Isolation Enables Purification of Murine Lineage Committed Cardiomyocytes. | Tarnawski L, Xian X, Monnerat G, Macaulay IC, Malan D, Borgman A, Wu SM, Fleischmann BK, Jovinge S | PloS one | 26323090 | PLoS One | 2015 |
Lift NIH restrictions on chimera research. | Sharma A, Sebastiano V, Scott CT, Magnus D, Koyano-Nakagawa N, Garry DJ, Witte ON, Nakauchi H, Wu JC, Weissman IL, Wu SM | Science (New York, N.Y.) | 26542560 | Science | 2015 Nov 6 |
Derivation of highly purified cardiomyocytes from human induced pluripotent stem cells using small molecule-modulated differentiation and subsequent glucose starvation. | Sharma A, Li G, Rajarajan K, Hamaguchi R, Burridge PW, Wu SM | Journal of visualized experiments : JoVE | 25867738 | J Vis Exp | 2015 Mar 18 |
iPSC-derived cardiomyocytes reveal abnormal TGF-β signalling in left ventricular non-compaction cardiomyopathy. | Kodo K, Ong SG, Jahanbani F, Termglinchan V, Hirono K, InanlooRahatloo K, Ebert AD, Shukla P, Abilez OJ, Churko JM, Karakikes I, Jung G, Ichida F, Wu SM, Snyder MP, Bernstein D, Wu JC | Nature cell biology | 27642787 | Nat Cell Biol | 2016 Oct |
Identification of cardiovascular lineage descendants at single-cell resolution. | Li G, Plonowska K, Kuppusamy R, Sturzu A, Wu SM | Development (Cambridge, England) | 25633351 | Development | 2015 Mar 1 |
Molecular regulation of cardiomyocyte differentiation. | Paige SL, Plonowska K, Xu A, Wu SM | Circulation research | 25593278 | Circ Res | 2015 Jan 16 |
Patching up broken hearts: cardiac cell therapy gets a bioengineered boost. | Serpooshan V, Wu SM | Cell stem cell | 25479741 | Cell Stem Cell | 2014 Dec 4 |
Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes. | Buikema JW, Lee S, Goodyer WR, Maas RG, Chirikian O, Li G, Miao Y, Paige SL, Lee D, Wu H, Paik DT, Rhee S, Tian L, Galdos FX, Puluca N, Beyersdorf B, Hu J, Beck A, Venkamatran S, Swami S, Wijnker P, Schuldt M, Dorsch LM, van Mil A, Red-Horse K, Wu JY, Geisen C, Hesse M, Serpooshan V, Jovinge S, Fleischmann BK, Doevendans PA, van der Velden J, Garcia KC, Wu JC, Sluijter JPG, Wu SM | Cell stem cell | 32619518 | Cell Stem Cell | 2020 Jul 2 |
Reactivation of the Nkx2.5 cardiac enhancer after myocardial infarction does not presage myogenesis. | Deutsch MA, Doppler SA, Li X, Lahm H, Santamaria G, Cuda G, Eichhorn S, Ratschiller T, Dzilic E, Dreßen M, Eckart A, Stark K, Massberg S, Bartels A, Rischpler C, Gilsbach R, Hein L, Fleischmann BK, Wu SM, Lange R, Krane M | Cardiovascular research | 29579159 | Cardiovasc Res | 2018 Jul 1 |
High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells. | Sharma A, Burridge PW, McKeithan WL, Serrano R, Shukla P, Sayed N, Churko JM, Kitani T, Wu H, Holmström A, Matsa E, Zhang Y, Kumar A, Fan AC, Del Álamo JC, Wu SM, Moslehi JJ, Mercola M, Wu JC | Science translational medicine | 28202772 | Sci Transl Med | 2017 Feb 15 |
Mammalian Heart Regeneration: The Race to the Finish Line. | Doppler SA, Deutsch MA, Serpooshan V, Li G, Dzilic E, Lange R, Krane M, Wu SM | Circulation research | 28209796 | Circ Res | 2017 Feb 17 |
Strategies for the acquisition of transcriptional and epigenetic information in single cells. | Li G, Dzilic E, Flores N, Shieh A, Wu SM | Journal of thoracic disease | 28446964 | J Thorac Dis | 2017 Mar |
Bioprinting Approaches to Engineering Vascularized 3D Cardiac Tissues. | Puluca N, Lee S, Doppler S, Münsterer A, Dreßen M, Krane M, Wu SM | Current cardiology reports | 31352612 | Curr Cardiol Rep | 2019 Jul 27 |
CRISPR/Cas9-based targeting of fluorescent reporters to human iPSCs to isolate atrial and ventricular-specific cardiomyocytes. | Chirikian O, Goodyer WR, Dzilic E, Serpooshan V, Buikema JW, McKeithan W, Wu H, Li G, Lee S, Merk M, Galdos F, Beck A, Ribeiro AJS, Paige S, Mercola M, Wu JC, Pruitt BL, Wu SM | Scientific reports | 33542270 | Sci Rep | 2021 Feb 4 |
Fates Aligned: Origins and Mechanisms of Ventricular Conduction System and Ventricular Wall Development. | Goodyer WR, Wu SM | Pediatric cardiology | 29594502 | Pediatr Cardiol | 2018 Aug |
4HNE Impairs Myocardial Bioenergetics in Congenital Heart Disease-Induced Right Ventricular Failure. | Hwang HV, Sandeep N, Paige SL, Ranjbarvaziri S, Hu DQ, Zhao M, Lan IS, Coronado M, Kooiker KB, Wu SM, Fajardo G, Bernstein D, Reddy S | Circulation | 32806952 | Circulation | 2020 Oct 27 |
Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris. | Tabula Muris Consortium, Overall coordination, Logistical coordination, Organ collection and processing, Library preparation and sequencing, Computational data analysis, Cell type annotation, Writing group, Supplemental text writing group, Principal investigators | Nature | 30283141 | Nature | 2018 Oct |
Stage-specific Effects of Bioactive Lipids on Human iPSC Cardiac Differentiation and Cardiomyocyte Proliferation. | Sharma A, Zhang Y, Buikema JW, Serpooshan V, Chirikian O, Kosaric N, Churko JM, Dzilic E, Shieh A, Burridge PW, Wu JC, Wu SM | Scientific reports | 29700394 | Sci Rep | 2018 Apr 26 |
Big bottlenecks in cardiovascular tissue engineering. | Huang NF, Serpooshan V, Morris VB, Sayed N, Pardon G, Abilez OJ, Nakayama KH, Pruitt BL, Wu SM, Yoon YS, Zhang J, Wu JC | Communications biology | 30480100 | Commun Biol | 2018 |
YY1 Expression Is Sufficient for the Maintenance of Cardiac Progenitor Cell State. | Gregoire S, Li G, Sturzu AC, Schwartz RJ, Wu SM | Stem cells (Dayton, Ohio) | 28580685 | Stem Cells | 2017 Aug |
Bioacoustic-enabled patterning of human iPSC-derived cardiomyocytes into 3D cardiac tissue. | Serpooshan V, Chen P, Wu H, Lee S, Sharma A, Hu DA, Venkatraman S, Ganesan AV, Usta OB, Yarmush M, Yang F, Wu JC, Demirci U, Wu SM | Biomaterials | 28376365 | Biomaterials | 2017 Jul |
Reassessment of c-Kit in Cardiac Cells: A Complex Interplay Between Expression, Fate, and Function. | Zhou B, Wu SM | Circulation research | 29929968 | Circ Res | 2018 Jun 22 |
Single-Cell Delineation of Who's on First and Second Heart Fields During Development. | Galdos FX, Wu SM | Circulation research | 31518166 | Circ Res | 2019 Aug 2 |
Cardiovascular tissue bioprinting: Physical and chemical processes. | Hu JB, Tomov ML, Buikema JW, Chen C, Mahmoudi M, Wu SM, Serpooshan V | Applied physics reviews | 32550960 | Appl Phys Rev | 2018 Dec |
Small RNAs make big impact in cardiac repair. | Krane M, Deutsch MA, Doppler S, Lange R, Wu SM | Circulation research | 25634967 | Circ Res | 2015 Jan 30 |
Members Only: Hypoxia-Induced Cell-Cycle Activation in Cardiomyocytes. | Sharma A, Wu SM | Cell metabolism | 26331604 | Cell Metab | 2015 Sep 1 |
Regenerative Medicine: Potential Mechanisms of Cardiac Recovery in Takotsubo Cardiomyopathy. | Chang AY, Kittle JT, Wu SM | Current treatment options in cardiovascular medicine | 26874708 | Curr Treat Options Cardiovasc Med | 2016 Mar |
Identification of Pathogenic Immune Cell Subsets Associated With Checkpoint Inhibitor-Induced Myocarditis. | Zhu H, Galdos FX, Lee D, Waliany S, Huang YV, Ryan J, Dang K, Neal JW, Wakelee HA, Reddy SA, Srinivas S, Lin LL, Witteles RM, Maecker HT, Davis MM, Nguyen PK, Wu SM | Circulation | 35762356 | Circulation | 2022 Jul 26 |
devCellPy is a machine learning-enabled pipeline for automated annotation of complex multilayered single-cell transcriptomic data. | Galdos FX, Xu S, Goodyer WR, Duan L, Huang YV, Lee S, Zhu H, Lee C, Wei N, Lee D, Wu SM | Nature communications | 36071107 | Nat Commun | 2022 Sep 7 |
Determining host metabolic limitations on viral replication via integrated modeling and experimental perturbation. | Birch EW, Ruggero NA, Covert MW | PLoS computational biology | 23093930 | PLoS Comput Biol | 2012 |
Measuring Signaling and RNA-Seq in the Same Cell Links Gene Expression to Dynamic Patterns of NF-κB Activation. | Lane K, Van Valen D, DeFelice MM, Macklin DN, Kudo T, Jaimovich A, Carr A, Meyer T, Pe'er D, Boutet SC, Covert MW | Cell systems | 28396000 | Cell Syst | 2017 Apr 26 |
Incorporation of flexible objectives and time-linked simulation with flux balance analysis. | Birch EW, Udell M, Covert MW | Journal of theoretical biology | 24361328 | J Theor Biol | 2014 Mar 21 |
Caries induced cytokine network in the odontoblast layer of human teeth. | Horst OV, Horst JA, Samudrala R, Dale BA | BMC immunology | 21261944 | BMC Immunol | 2011 Jan 24 |
IGF1R variants associated with isolated single suture craniosynostosis. | Cunningham ML, Horst JA, Rieder MJ, Hing AV, Stanaway IB, Park SS, Samudrala R, Speltz ML | American journal of medical genetics. Part A | 21204214 | Am J Med Genet A | 2011 Jan |
Computational prediction of type III and IV secreted effectors in gram-negative bacteria. | McDermott JE, Corrigan A, Peterson E, Oehmen C, Niemann G, Cambronne ED, Sharp D, Adkins JN, Samudrala R, Heffron F | Infection and immunity | 20974833 | Infect Immun | 2011 Jan |
Probing the molecular mechanisms of quartz-binding peptides. | Oren EE, Notman R, Kim IW, Evans JS, Walsh TR, Samudrala R, Tamerler C, Sarikaya M | Langmuir : the ACS journal of surfaces and colloids | 20499870 | Langmuir | 2010 Jul 6 |
GPU-Q-J, a fast method for calculating root mean square deviation (RMSD) after optimal superposition. | Hung LH, Guerquin M, Samudrala R | BMC research notes | 21453553 | BMC Res Notes | 2011 Apr 1 |
Cementomimetics-constructing a cementum-like biomineralized microlayer via amelogenin-derived peptides. | Gungormus M, Oren EE, Horst JA, Fong H, Hnilova M, Somerman MJ, Snead ML, Samudrala R, Tamerler C, Sarikaya M | International journal of oral science | 22743342 | Int J Oral Sci | 2012 Jun |
Disease risk of missense mutations using structural inference from predicted function. | Horst JA, Wang K, Horst OV, Cunningham ML, Samudrala R | Current protein & peptide science | 20887259 | Curr Protein Pept Sci | 2010 Nov |
Composite Sequence-Structure Stability Models as Screening Tools for Identifying Vulnerable Targets for HIV Drug and Vaccine Development. | Manocheewa S, Mittler JE, Samudrala R, Mullins JI | Viruses | 26556362 | Viruses | 2015 Nov 4 |
Data access for the 1,000 Plants (1KP) project. | Matasci N, Hung LH, Yan Z, Carpenter EJ, Wickett NJ, Mirarab S, Nguyen N, Warnow T, Ayyampalayam S, Barker M, Burleigh JG, Gitzendanner MA, Wafula E, Der JP, dePamphilis CW, Roure B, Philippe H, Ruhfel BR, Miles NW, Graham SW, Mathews S, Surek B, Melkonian M, Soltis DE, Soltis PS, Rothfels C, Pokorny L, Shaw JA, DeGironimo L, Stevenson DW, Villarreal JC, Chen T, Kutchan TM, Rolf M, Baucom RS, Deyholos MK, Samudrala R, Tian Z, Wu X, Sun X, Zhang Y, Wang J, Leebens-Mack J, Wong GK | GigaScience | 25625010 | Gigascience | 2014 |
Adhesion and fusion efficiencies of human immunodeficiency virus type 1 (HIV-1) surface proteins. | Dobrowsky TM, Rabi SA, Nedellec R, Daniels BR, Mullins JI, Mosier DE, Siliciano RF, Wirtz D | Scientific reports | 24145278 | Sci Rep | 2013 Oct 22 |
Structural optimization and de novo design of dengue virus entry inhibitory peptides. | Costin JM, Jenwitheesuk E, Lok SM, Hunsperger E, Conrads KA, Fontaine KA, Rees CR, Rossmann MG, Isern S, Samudrala R, Michael SF | PLoS neglected tropical diseases | 20582308 | PLoS Negl Trop Dis | 2010 Jun 22 |
Viral linkage in HIV-1 seroconverters and their partners in an HIV-1 prevention clinical trial. | Campbell MS, Mullins JI, Hughes JP, Celum C, Wong KG, Raugi DN, Sorensen S, Stoddard JN, Zhao H, Deng W, Kahle E, Panteleeff D, Baeten JM, McCutchan FE, Albert J, Leitner T, Wald A, Corey L, Lingappa JR, Partners in Prevention HSV/HIV Transmission Study Team | PloS one | 21399681 | PLoS One | 2011 Mar 2 |
An HIV epidemic model based on viral load dynamics: value in assessing empirical trends in HIV virulence and community viral load. | Herbeck JT, Mittler JE, Gottlieb GS, Mullins JI | PLoS computational biology | 24945322 | PLoS Comput Biol | 2014 Jun |
The evolution and functional repertoire of translation proteins following the origin of life. | Goldman AD, Samudrala R, Baross JA | Biology direct | 20377891 | Biol Direct | 2010 Apr 8 |
Pseudomonas aeruginosa uses a cyclic-di-GMP-regulated adhesin to reinforce the biofilm extracellular matrix. | Borlee BR, Goldman AD, Murakami K, Samudrala R, Wozniak DJ, Parsek MR | Molecular microbiology | 20088866 | Mol Microbiol | 2010 Feb |
Viral entry inhibitors block dengue antibody-dependent enhancement in vitro. | Nicholson CO, Costin JM, Rowe DK, Lin L, Jenwitheesuk E, Samudrala R, Isern S, Michael SF | Antiviral research | 21093488 | Antiviral Res | 2011 Jan |
Distal effect of amino acid substitutions in CYP2C9 polymorphic variants causes differences in interatomic interactions against (S)-warfarin. | Lertkiatmongkol P, Assawamakin A, White G, Chopra G, Rongnoparut P, Samudrala R, Tongsima S | PloS one | 24023924 | PLoS One | 2013 |
A generalized knowledge-based discriminatory function for biomolecular interactions. | Bernard B, Samudrala R | Proteins | 19127590 | Proteins | 2009 Jul |
fast_protein_cluster: parallel and optimized clustering of large-scale protein modeling data. | Hung LH, Samudrala R | Bioinformatics (Oxford, England) | 24532722 | Bioinformatics | 2014 Jun 15 |
Mycobacterium Cytidylate Kinase Appears to Be an Undruggable Target. | Craig JK, Risler JK, Loesch KA, Dong W, Baker D, Barrett LK, Subramanian S, Samudrala R, Van Voorhis WC | Journal of biomolecular screening | 27146385 | J Biomol Screen | 2016 Aug |
Evolutionary transients in the rice transcriptome. | Wang J, Zhang J, Li R, Zheng H, Li J, Zhang Y, Li H, Ni P, Li S, Li S, Wang J, Liu D, McDermott J, Samudrala R, Liu S, Wang J, Yang H, Yu J, Wong GK | Genomics, proteomics & bioinformatics | 21382590 | Genomics Proteomics Bioinformatics | 2010 Dec |
Solution study of engineered quartz binding peptides using replica exchange molecular dynamics. | Notman R, Oren EE, Tamerler C, Sarikaya M, Samudrala R, Walsh TR | Biomacromolecules | 20964422 | Biomacromolecules | 2010 Dec 13 |
A protein sequence meta-functional signature for calcium binding residue prediction. | Horst JA, Samudrala R | Pattern recognition letters | 20824111 | Pattern Recognit Lett | 2010 Oct 15 |
Structure of human telomerase holoenzyme with bound telomeric DNA. | Ghanim GE, Fountain AJ, van Roon AM, Rangan R, Das R, Collins K, Nguyen THD | Nature | 33883742 | Nature | 2021 May |
Nanopore molecular trajectories of a eukaryotic reverse transcriptase reveal a long-range RNA structure sensing mechanism. | Shaw A, Craig JM, Amiri H, Kim J, Upton HE, Pimentel SC, Huang JR, Marqusee S, Collins K, Gundlach JH, Bustamante CJ | bioRxiv : the preprint server for biology | 37066208 | bioRxiv | 2023 Nov 1 |
eIF3 engages with 3'-UTR termini of highly translated mRNAs. | Mestre-Fos S, Ferguson L, Trinidad M, Ingolia NT, Cate JHD | bioRxiv : the preprint server for biology | 37986910 | bioRxiv | 2024 Nov 24 |
Improved precision, sensitivity, and adaptability of ordered two-template relay cDNA library preparation for RNA sequencing. | Ferguson L, Upton HE, Pimentel SC, Jeans C, Ingolia NT, Collins K | RNA (New York, N.Y.) | 39626888 | RNA | 2025 Jan 22 |
eIF3 engages with 3'-UTR termini of highly translated mRNAs. | Mestre-Fos S, Ferguson L, Trinidad MI, Ingolia NT, Cate JHD | eLife | 39879133 | Elife | 2025 Jan 29 |
Low-bias ncRNA libraries using ordered two-template relay: Serial template jumping by a modified retroelement reverse transcriptase. | Upton HE, Ferguson L, Temoche-Diaz MM, Liu XM, Pimentel SC, Ingolia NT, Schekman R, Collins K | Proceedings of the National Academy of Sciences of the United States of America | 34649994 | Proc Natl Acad Sci U S A | 2021 Oct 19 |
Conserved and divergent DNA recognition specificities and functions of R2 retrotransposon N-terminal domains. | Lee RJ, Horton CA, Van Treeck B, McIntyre JJR, Collins K | Cell reports | 38753487 | Cell Rep | 2024 May 28 |
Structure and sequence at an RNA template 5' end influence insertion of transgenes by an R2 retrotransposon protein. | Palm SM, Horton CA, Zhang X, Collins K | RNA (New York, N.Y.) | 38960642 | RNA | 2024 Aug 16 |
Distinct and overlapping RNA determinants for binding and target-primed reverse transcription by Bombyx mori R2 retrotransposon protein. | Rodríguez-Vargas A, Collins K | Nucleic acids research | 38499488 | Nucleic Acids Res | 2024 Jun 24 |
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Separable structural requirements for cDNA synthesis, nontemplated extension, and template jumping by a non-LTR retroelement reverse transcriptase. | Pimentel SC, Upton HE, Collins K | The Journal of biological chemistry | 35065960 | J Biol Chem | 2022 Mar |
Harnessing eukaryotic retroelement proteins for transgene insertion into human safe-harbor loci. | Zhang X, Van Treeck B, Horton CA, McIntyre JJR, Palm SM, Shumate JL, Collins K | Nature biotechnology | 38379101 | Nat Biotechnol | 2025 Jan |
Streamlined and sensitive mono- and di-ribosome profiling in yeast and human cells. | Ferguson L, Upton HE, Pimentel SC, Mok A, Lareau LF, Collins K, Ingolia NT | Nature methods | 37783882 | Nat Methods | 2023 Nov |
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Template and target-site recognition by human LINE-1 in retrotransposition. | Thawani A, Ariza AJF, Nogales E, Collins K | Nature | 38096901 | Nature | 2024 Feb |
RNA editing with CRISPR-Cas13. | Cox DBT, Gootenberg JS, Abudayyeh OO, Franklin B, Kellner MJ, Joung J, Zhang F | Science (New York, N.Y.) | 29070703 | Science | 2017 Nov 24 |
Diverse enzymatic activities mediate antiviral immunity in prokaryotes. | Gao L, Altae-Tran H, Böhning F, Makarova KS, Segel M, Schmid-Burgk JL, Koob J, Wolf YI, Koonin EV, Zhang F | Science (New York, N.Y.) | 32855333 | Science | 2020 Aug 28 |
Genomic determinants of pathogenicity in SARS-CoV-2 and other human coronaviruses. | Gussow AB, Auslander N, Faure G, Wolf YI, Zhang F, Koonin EV | Proceedings of the National Academy of Sciences of the United States of America | 32522874 | Proc Natl Acad Sci U S A | 2020 Jun 30 |
Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening. | Wang G, Chow RD, Ye L, Guzman CD, Dai X, Dong MB, Zhang F, Sharp PA, Platt RJ, Chen S | Science advances | 29503867 | Sci Adv | 2018 Feb |
Engineering of CRISPR-Cas12b for human genome editing. | Strecker J, Jones S, Koopal B, Schmid-Burgk J, Zetsche B, Gao L, Makarova KS, Koonin EV, Zhang F | Nature communications | 30670702 | Nat Commun | 2019 Jan 22 |
Structure and engineering of the minimal type VI CRISPR-Cas13bt3. | Nakagawa R, Kannan S, Altae-Tran H, Takeda SN, Tomita A, Hirano H, Kusakizako T, Nishizawa T, Yamashita K, Zhang F, Nishimasu H, Nureki O | Molecular cell | 36027912 | Mol Cell | 2022 Sep 1 |
A transcription factor atlas of directed differentiation. | Joung J, Ma S, Tay T, Geiger-Schuller KR, Kirchgatterer PC, Verdine VK, Guo B, Arias-Garcia MA, Allen WE, Singh A, Kuksenko O, Abudayyeh OO, Gootenberg JS, Fu Z, Macrae RK, Buenrostro JD, Regev A, Zhang F | Cell | 36608654 | Cell | 2023 Jan 5 |
RNA-activated protein cleavage with a CRISPR-associated endopeptidase. | Strecker J, Demircioglu FE, Li D, Faure G, Wilkinson ME, Gootenberg JS, Abudayyeh OO, Nishimasu H, Macrae RK, Zhang F | Science (New York, N.Y.) | 36423276 | Science | 2022 Nov 25 |
Microfluidic Enrichment and Computational Analysis of Rare Sequences from Mixed Genomic Samples for Metagenomic Mining. | Cui N, Faure G, Singh A, Macrae R, Zhang F | The CRISPR journal | 36206017 | CRISPR J | 2022 Oct |
RNA-guided DNA insertion with CRISPR-associated transposases. | Strecker J, Ladha A, Gardner Z, Schmid-Burgk JL, Makarova KS, Koonin EV, Zhang F | Science (New York, N.Y.) | 31171706 | Science | 2019 Jul 5 |
Field-deployable viral diagnostics using CRISPR-Cas13. | Myhrvold C, Freije CA, Gootenberg JS, Abudayyeh OO, Metsky HC, Durbin AF, Kellner MJ, Tan AL, Paul LM, Parham LA, Garcia KF, Barnes KG, Chak B, Mondini A, Nogueira ML, Isern S, Michael SF, Lorenzana I, Yozwiak NL, MacInnis BL, Bosch I, Gehrke L, Zhang F, Sabeti PC | Science (New York, N.Y.) | 29700266 | Science | 2018 Apr 27 |
Highly Parallel Profiling of Cas9 Variant Specificity. | Schmid-Burgk JL, Gao L, Li D, Gardner Z, Strecker J, Lash B, Zhang F | Molecular cell | 32187529 | Mol Cell | 2020 May 21 |
Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery. | Segel M, Lash B, Song J, Ladha A, Liu CC, Jin X, Mekhedov SL, Macrae RK, Koonin EV, Zhang F | Science (New York, N.Y.) | 34413232 | Science | 2021 Aug 20 |
Dual modes of CRISPR-associated transposon homing. | Saito M, Ladha A, Strecker J, Faure G, Neumann E, Altae-Tran H, Macrae RK, Zhang F | Cell | 33770501 | Cell | 2021 Apr 29 |
LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding. | Ludwig KU, Schmithausen RM, Li D, Jacobs ML, Hollstein R, Blumenstock K, Liebing J, Słabicki M, Ben-Shmuel A, Israeli O, Weiss S, Ebert TS, Paran N, Rüdiger W, Wilbring G, Feldman D, Lippke B, Ishorst N, Hochfeld LM, Beins EC, Kaltheuner IH, Schmitz M, Wöhler A, Döhla M, Sib E, Jentzsch M, Moench EC, Borrajo JD, Strecker J, Reinhardt J, Cleary B, Geyer M, Hölzel M, Macrae R, Nöthen MM, Hoffmann P, Exner M, Regev A, Zhang F, Schmid-Burgk JL | Nature biotechnology | 34188222 | Nat Biotechnol | 2021 Dec |
Compact RNA editors with small Cas13 proteins. | Kannan S, Altae-Tran H, Jin X, Madigan VJ, Oshiro R, Makarova KS, Koonin EV, Zhang F | Nature biotechnology | 34462587 | Nat Biotechnol | 2022 Feb |
The widespread IS200/IS605 transposon family encodes diverse programmable RNA-guided endonucleases. | Altae-Tran H, Kannan S, Demircioglu FE, Oshiro R, Nety SP, McKay LJ, Dlakić M, Inskeep WP, Makarova KS, Macrae RK, Koonin EV, Zhang F | Science (New York, N.Y.) | 34591643 | Science | 2021 Oct |
UG/Abi: a highly diverse family of prokaryotic reverse transcriptases associated with defense functions. | Mestre MR, Gao LA, Shah SA, López-Beltrán A, González-Delgado A, Martínez-Abarca F, Iranzo J, Redrejo-Rodríguez M, Zhang F, Toro N | Nucleic acids research | 35648479 | Nucleic Acids Res | 2022 Jun 24 |
CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity. | Joung J, Kirchgatterer PC, Singh A, Cho JH, Nety SP, Larson RC, Macrae RK, Deasy R, Tseng YY, Maus MV, Zhang F | Nature communications | 35338135 | Nat Commun | 2022 Mar 25 |
Structure of the OMEGA nickase IsrB in complex with ωRNA and target DNA. | Hirano S, Kappel K, Altae-Tran H, Faure G, Wilkinson ME, Kannan S, Demircioglu FE, Yan R, Shiozaki M, Yu Z, Makarova KS, Koonin EV, Macrae RK, Zhang F | Nature | 36224386 | Nature | 2022 Oct |
Nucleic Acid Detection of Plant Genes Using CRISPR-Cas13. | Abudayyeh OO, Gootenberg JS, Kellner MJ, Zhang F | The CRISPR journal | 31225754 | CRISPR J | 2019 Jun |
The evolution of red color vision is linked to coordinated rhodopsin tuning in lycaenid butterflies. | Liénard MA, Bernard GD, Allen A, Lassance JM, Song S, Childers RR, Yu N, Ye D, Stephenson A, Valencia-Montoya WA, Salzman S, Whitaker MRL, Calonje M, Zhang F, Pierce NE | Proceedings of the National Academy of Sciences of the United States of America | 33547236 | Proc Natl Acad Sci U S A | 2021 Feb 9 |
Ongoing global and regional adaptive evolution of SARS-CoV-2. | Rochman ND, Wolf YI, Faure G, Mutz P, Zhang F, Koonin EV | Proceedings of the National Academy of Sciences of the United States of America | 34292871 | Proc Natl Acad Sci U S A | 2021 Jul 20 |
Optical Pooled Screens in Human Cells. | Feldman D, Singh A, Schmid-Burgk JL, Carlson RJ, Mezger A, Garrity AJ, Zhang F, Blainey PC | Cell | 31626775 | Cell | 2019 Oct 17 |
Prokaryotic innate immunity through pattern recognition of conserved viral proteins. | Gao LA, Wilkinson ME, Strecker J, Makarova KS, Macrae RK, Koonin EV, Zhang F | Science (New York, N.Y.) | 35951700 | Science | 2022 Aug 12 |
Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity. | Sorek M, Oweis W, Nissim-Rafinia M, Maman M, Simon S, Hession CC, Adiconis X, Simmons SK, Sanjana NE, Shi X, Lu C, Pan JQ, Xu X, Pouladi MA, Ellerby LM, Zhang F, Levin JZ, Meshorer E | Genome biology | 33663567 | Genome Biol | 2021 Mar 4 |
DNA Microscopy: Optics-free Spatio-genetic Imaging by a Stand-Alone Chemical Reaction. | Weinstein JA, Regev A, Zhang F | Cell | 31230717 | Cell | 2019 Jun 27 |
High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage. | Slaymaker IM, Mesa P, Kellner MJ, Kannan S, Brignole E, Koob J, Feliciano PR, Stella S, Abudayyeh OO, Gootenberg JS, Strecker J, Montoya G, Zhang F | Cell reports | 30917325 | Cell Rep | 2019 Mar 26 |
Unexpected connections between type VI-B CRISPR-Cas systems, bacterial natural competence, ubiquitin signaling network and DNA modification through a distinct family of membrane proteins. | Makarova KS, Gao L, Zhang F, Koonin EV | FEMS microbiology letters | 31089700 | FEMS Microbiol Lett | 2019 Apr 1 |
In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes. | Jin X, Simmons SK, Guo A, Shetty AS, Ko M, Nguyen L, Jokhi V, Robinson E, Oyler P, Curry N, Deangeli G, Lodato S, Levin JZ, Regev A, Zhang F, Arlotta P | Science (New York, N.Y.) | 33243861 | Science | 2020 Nov 27 |
Detection of SARS-CoV-2 with SHERLOCK One-Pot Testing. | Joung J, Ladha A, Saito M, Kim NG, Woolley AE, Segel M, Barretto RPJ, Ranu A, Macrae RK, Faure G, Ioannidi EI, Krajeski RN, Bruneau R, Huang MW, Yu XG, Li JZ, Walker BD, Hung DT, Greninger AL, Jerome KR, Gootenberg JS, Abudayyeh OO, Zhang F | The New England journal of medicine | 32937062 | N Engl J Med | 2020 Oct 8 |
Effects of 3D culturing conditions on the transcriptomic profile of stem-cell-derived neurons. | Tekin H, Simmons S, Cummings B, Gao L, Adiconis X, Hession CC, Ghoshal A, Dionne D, Choudhury SR, Yesilyurt V, Sanjana NE, Shi X, Lu C, Heidenreich M, Pan JQ, Levin JZ, Zhang F | Nature biomedical engineering | 30271673 | Nat Biomed Eng | 2018 Jul |
Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6. | Gootenberg JS, Abudayyeh OO, Kellner MJ, Joung J, Collins JJ, Zhang F | Science (New York, N.Y.) | 29449508 | Science | 2018 Apr 27 |
CRISPR-Based Therapeutic Genome Editing: Strategies and In Vivo Delivery by AAV Vectors. | Wang D, Zhang F, Gao G | Cell | 32243786 | Cell | 2020 Apr 2 |
Programmable Inhibition and Detection of RNA Viruses Using Cas13. | Freije CA, Myhrvold C, Boehm CK, Lin AE, Welch NL, Carter A, Metsky HC, Luo CY, Abudayyeh OO, Gootenberg JS, Yozwiak NL, Zhang F, Sabeti PC | Molecular cell | 31607545 | Mol Cell | 2019 Dec 5 |
Computational models in cardiology. | Niederer SA, Lumens J, Trayanova NA | Nature reviews. Cardiology | 30361497 | Nat Rev Cardiol | 2019 Feb |
Virtual electrophysiological study as a tool for evaluating efficacy of MRI techniques in predicting adverse arrhythmic events in ischemic patients. | Ukwatta E, Nikolov P, Zabihollahy F, Trayanova NA, Wright GA | Physics in medicine and biology | 30412472 | Phys Med Biol | 2018 Nov 9 |
Cardiac Optogenetics: 2018. | Boyle PM, Karathanos TV, Trayanova NA | JACC. Clinical electrophysiology | 29749932 | JACC Clin Electrophysiol | 2018 Feb |
Optimal contrast-enhanced MRI image thresholding for accurate prediction of ventricular tachycardia using ex-vivo high resolution models. | Deng D, Nikolov P, Arevalo HJ, Trayanova NA | Computers in biology and medicine | 30301573 | Comput Biol Med | 2018 Nov 1 |
Association of regional myocardial conduction velocity with the distribution of hypoattenuation on contrast-enhanced perfusion computed tomography in patients with postinfarct ventricular tachycardia. | Ustunkaya T, Desjardins B, Liu B, Zahid S, Park J, Saju N, Trayanova N, Zimmerman SL, Marchlinski FE, Nazarian S | Heart rhythm | 30935494 | Heart Rhythm | 2019 Apr |
Computationally guided personalized targeted ablation of persistent atrial fibrillation. | Boyle PM, Zghaib T, Zahid S, Ali RL, Deng D, Franceschi WH, Hakim JB, Murphy MJ, Prakosa A, Zimmerman SL, Ashikaga H, Marine JE, Kolandaivelu A, Nazarian S, Spragg DD, Calkins H, Trayanova NA | Nature biomedical engineering | 31427780 | Nat Biomed Eng | 2019 Nov |
Spatial dispersion analysis of LGE-CMR for prediction of ventricular arrhythmias in patients with cardiac sarcoidosis. | Aronis KN, Okada DR, Xie E, Daimee UA, Prakosa A, Gilotra NA, Wu KC, Trayanova N, Chrispin J | Pacing and clinical electrophysiology : PACE | 34766627 | Pacing Clin Electrophysiol | 2021 Dec |
Computational modeling of aberrant electrical activity following remuscularization with intramyocardially injected pluripotent stem cell-derived cardiomyocytes. | Yu JK, Liang JA, Weinberg SH, Trayanova NA | Journal of molecular and cellular cardiology | 34487753 | J Mol Cell Cardiol | 2022 Jan |
Optogenetics-enabled dynamic modulation of action potential duration in atrial tissue: feasibility of a novel therapeutic approach. | Karathanos TV, Boyle PM, Trayanova NA | Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology | 25362173 | Europace | 2014 Nov |
Computational analysis of the effect of valvular regurgitation on ventricular mechanics using a 3D electromechanics model. | Lim KM, Hong SB, Lee BK, Shim EB, Trayanova N | The journal of physiological sciences : JPS | 25644379 | J Physiol Sci | 2015 Mar |
Optogenetics-enabled assessment of viral gene and cell therapy for restoration of cardiac excitability. | Ambrosi CM, Boyle PM, Chen K, Trayanova NA, Entcheva E | Scientific reports | 26621212 | Sci Rep | 2015 Dec 1 |
Intermittent drivers anchoring to structural heterogeneities as a major pathophysiological mechanism of human persistent atrial fibrillation. | Haissaguerre M, Shah AJ, Cochet H, Hocini M, Dubois R, Efimov I, Vigmond E, Bernus O, Trayanova N | The Journal of physiology | 26890861 | J Physiol | 2016 May 1 |
Arrhythmia risk stratification of patients after myocardial infarction using personalized heart models. | Arevalo HJ, Vadakkumpadan F, Guallar E, Jebb A, Malamas P, Wu KC, Trayanova NA | Nature communications | 27164184 | Nat Commun | 2016 May 10 |
Computational rabbit models to investigate the initiation, perpetuation, and termination of ventricular arrhythmia. | Arevalo HJ, Boyle PM, Trayanova NA | Progress in biophysics and molecular biology | 27334789 | Prog Biophys Mol Biol | 2016 Jul |
Opsin spectral sensitivity determines the effectiveness of optogenetic termination of ventricular fibrillation in the human heart: a simulation study. | Karathanos TV, Bayer JD, Wang D, Boyle PM, Trayanova NA | The Journal of physiology | 26941055 | J Physiol | 2016 Dec 1 |
A feasibility study of arrhythmia risk prediction in patients with myocardial infarction and preserved ejection fraction. | Deng D, Arevalo HJ, Prakosa A, Callans DJ, Trayanova NA | Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology | 28011832 | Europace | 2016 Dec |
Towards personalized computational modelling of the fibrotic substrate for atrial arrhythmia. | Boyle PM, Zahid S, Trayanova NA | Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology | 28011841 | Europace | 2016 Dec |
Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm. | Cerrone M, Montnach J, Lin X, Zhao YT, Zhang M, Agullo-Pascual E, Leo-Macias A, Alvarado FJ, Dolgalev I, Karathanos TV, Malkani K, Van Opbergen CJM, van Bavel JJA, Yang HQ, Vasquez C, Tester D, Fowler S, Liang F, Rothenberg E, Heguy A, Morley GE, Coetzee WA, Trayanova NA, Ackerman MJ, van Veen TAB, Valdivia HH, Delmar M | Nature communications | 28740174 | Nat Commun | 2017 Jul 24 |
Efficient preloading of the ventricles by a properly timed atrial contraction underlies stroke work improvement in the acute response to cardiac resynchronization therapy. | Hu Y, Gurev V, Constantino J, Trayanova N | Heart rhythm | 23928177 | Heart Rhythm | 2013 Dec |
A New MRI-Based Model of Heart Function with Coupled Hemodynamics and Application to Normal and Diseased Canine Left Ventricles. | Choi YJ, Constantino J, Vedula V, Trayanova N, Mittal R | Frontiers in bioengineering and biotechnology | 26442254 | Front Bioeng Biotechnol | 2015 |
Mathematical approaches to understanding and imaging atrial fibrillation: significance for mechanisms and management. | Trayanova NA | Circulation research | 24763468 | Circ Res | 2014 Apr 25 |
"Beauty is a light in the heart": the transformative potential of optogenetics for clinical applications in cardiovascular medicine. | Boyle PM, Karathanos TV, Trayanova NA | Trends in cardiovascular medicine | 25453984 | Trends Cardiovasc Med | 2015 Feb |
Myocardial infarct segmentation and reconstruction from 2D late-gadolinium enhanced magnetic resonance images. | Ukwatta E, Yuan J, Qiu W, Wu KC, Trayanova N, Vadakkumpadan F | Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention | 25485423 | Med Image Comput Comput Assist Interv | 2014 |
Myocardial Infarct Segmentation From Magnetic Resonance Images for Personalized Modeling of Cardiac Electrophysiology. | Ukwatta E, Arevalo H, Li K, Yuan J, Qiu W, Malamas P, Wu KC, Trayanova NA, Vadakkumpadan F | IEEE transactions on medical imaging | 26731693 | IEEE Trans Med Imaging | 2016 Jun |
Precisely parameterized experimental and computational models of tissue organization. | Molitoris JM, Paliwal S, Sekar RB, Blake R, Park J, Trayanova NA, Tung L, Levchenko A | Integrative biology : quantitative biosciences from nano to macro | 26822672 | Integr Biol (Camb) | 2016 Feb |
Computational models of heart disease. | Smith N, Trayanova N | Drug discovery today. Disease models | 26843884 | Drug Discov Today Dis Models | 2014 Winter |
Accurate Conduction Velocity Maps and Their Association With Scar Distribution on Magnetic Resonance Imaging in Patients With Postinfarction Ventricular Tachycardias. | Aronis KN, Ali RL, Prakosa A, Ashikaga H, Berger RD, Hakim JB, Liang J, Tandri H, Teng F, Chrispin J, Trayanova NA | Circulation. Arrhythmia and electrophysiology | 32191131 | Circ Arrhythm Electrophysiol | 2020 Apr |
Ventricular arrhythmia risk prediction in repaired Tetralogy of Fallot using personalized computational cardiac models. | Shade JK, Cartoski MJ, Nikolov P, Prakosa A, Doshi A, Binka E, Olivieri L, Boyle PM, Spevak PJ, Trayanova NA | Heart rhythm | 31589989 | Heart Rhythm | 2020 Mar |
Epicardial Conduction Speed, Electrogram Abnormality, and Computed Tomography Attenuation Associations in Arrhythmogenic Right Ventricular Cardiomyopathy. | Ustunkaya T, Desjardins B, Wedan R, Chahal CAA, Zimmerman SL, Saju N, Zahid S, Sharma A, Han Y, Trayanova N, Marchlinski FE, Calkins H, Tandri H, Nazarian S | JACC. Clinical electrophysiology | 31648740 | JACC Clin Electrophysiol | 2019 Oct |
Tropomyosin dynamics during cardiac muscle contraction as governed by a multi-well energy landscape. | Aboelkassem Y, Trayanova N | Progress in biophysics and molecular biology | 30145015 | Prog Biophys Mol Biol | 2019 Jul |
From genetics to smart watches: developments in precision cardiology. | Trayanova N | Nature reviews. Cardiology | 30568275 | Nat Rev Cardiol | 2019 Feb |
Spatially Adaptive Multi-Scale Optimization for Local Parameter Estimation in Cardiac Electrophysiology. | Dhamala J, Arevalo HJ, Sapp J, Horacek M, Wu KC, Trayanova NA, Wang L | IEEE transactions on medical imaging | 28459685 | IEEE Trans Med Imaging | 2017 Sep |
Role of 3-Dimensional Architecture of Scar and Surviving Tissue in Ventricular Tachycardia: Insights From High-Resolution Ex Vivo Porcine Models. | Pashakhanloo F, Herzka DA, Halperin H, McVeigh ER, Trayanova NA | Circulation. Arrhythmia and electrophysiology | 29880529 | Circ Arrhythm Electrophysiol | 2018 Jun |
Exploring susceptibility to atrial and ventricular arrhythmias resulting from remodeling of the passive electrical properties in the heart: a simulation approach. | Trayanova NA, Boyle PM, Arevalo HJ, Zahid S | Frontiers in physiology | 25429272 | Front Physiol | 2014 |
Virtual 3D heart models to aid pacemaker implantation in children. | Trayanova NA | Future cardiology | 24344653 | Future Cardiol | 2014 Jan |
Computational modeling of cardiac optogenetics: Methodology overview & review of findings from simulations. | Boyle PM, Karathanos TV, Entcheva E, Trayanova NA | Computers in biology and medicine | 26002074 | Comput Biol Med | 2015 Oct 1 |
New insights into defibrillation of the heart from realistic simulation studies. | Trayanova NA, Rantner LJ | Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology | 24798960 | Europace | 2014 May |
Myofiber Architecture of the Human Atria as Revealed by Submillimeter Diffusion Tensor Imaging. | Pashakhanloo F, Herzka DA, Ashikaga H, Mori S, Gai N, Bluemke DA, Trayanova NA, McVeigh ER | Circulation. Arrhythmia and electrophysiology | 27071829 | Circ Arrhythm Electrophysiol | 2016 Apr |
Mechanisms linking electrical alternans and clinical ventricular arrhythmia in human heart failure. | Bayer JD, Lalani GG, Vigmond EJ, Narayan SM, Trayanova NA | Heart rhythm | 27215536 | Heart Rhythm | 2016 Sep |
Computational Identification of Ventricular Arrhythmia Risk in Pediatric Myocarditis. | Cartoski MJ, Nikolov PP, Prakosa A, Boyle PM, Spevak PJ, Trayanova NA | Pediatric cardiology | 30840104 | Pediatr Cardiol | 2019 Apr |
Light-based Approaches to Cardiac Arrhythmia Research: From Basic Science to Translational Applications. | Karathanos TV, Boyle PM, Trayanova NA | Clinical Medicine Insights. Cardiology | 27840581 | Clin Med Insights Cardiol | 2016 |
Feasibility of using patient-specific models and the "minimum cut" algorithm to predict optimal ablation targets for left atrial flutter. | Zahid S, Whyte KN, Schwarz EL, Blake RC 3rd, Boyle PM, Chrispin J, Prakosa A, Ipek EG, Pashakhanloo F, Halperin HR, Calkins H, Berger RD, Nazarian S, Trayanova NA | Heart rhythm | 27108938 | Heart Rhythm | 2016 Aug |
Initiation of a High-Frequency Jet Ventilation Strategy for Catheter Ablation for Atrial Fibrillation: Safety and Outcomes Data. | Sivasambu B, Hakim JB, Barodka V, Chrispin J, Berger RD, Ashikaga H, Ciuffo L, Tao S, Calkins H, Marine JE, Trayanova N, Spragg DD | JACC. Clinical electrophysiology | 30573114 | JACC Clin Electrophysiol | 2018 Dec |
Arrhythmogenic propensity of the fibrotic substrate after atrial fibrillation ablation: a longitudinal study using magnetic resonance imaging-based atrial models. | Ali RL, Hakim JB, Boyle PM, Zahid S, Sivasambu B, Marine JE, Calkins H, Trayanova NA, Spragg DD | Cardiovascular research | 30977811 | Cardiovasc Res | 2019 Oct 1 |
Degradation of T-Tubular Microdomains and Altered cAMP Compartmentation Lead to Emergence of Arrhythmogenic Triggers in Heart Failure Myocytes: An in silico Study. | Loucks AD, O'Hara T, Trayanova NA | Frontiers in physiology | 30564142 | Front Physiol | 2018 |
Association of left atrial epicardial adipose tissue with electrogram bipolar voltage and fractionation: Electrophysiologic substrates for atrial fibrillation. | Zghaib T, Ipek EG, Zahid S, Balouch MA, Misra S, Ashikaga H, Berger RD, Marine JE, Spragg DD, Zimmerman SL, Zipunnikov V, Trayanova N, Calkins H, Nazarian S | Heart rhythm | 27546816 | Heart Rhythm | 2016 Dec |
Effect of KCNQ1 G229D mutation on cardiac pumping efficacy and reentrant dynamics in ventricles: Computational study. | Yuniarti AR, Setianto F, Marcellinus A, Hwang HJ, Choi SW, Trayanova N, Lim KM | International journal for numerical methods in biomedical engineering | 29488358 | Int J Numer Method Biomed Eng | 2018 Jun |
Biological substrate modification suppresses ventricular arrhythmias in a porcine model of chronic ischaemic cardiomyopathy. | Dawkins JF, Ehdaie A, Rogers R, Soetkamp D, Valle J, Holm K, Sanchez L, Tremmel I, Nawaz A, Shehata M, Wang X, Prakosa A, Yu J, Van Eyk JE, Trayanova N, Marbán E, Cingolani E | European heart journal | 35262692 | Eur Heart J | 2022 Jun 6 |
Substrate Spatial Complexity Analysis for the Prediction of Ventricular Arrhythmias in Patients With Ischemic Cardiomyopathy. | Okada DR, Miller J, Chrispin J, Prakosa A, Trayanova N, Jones S, Maggioni M, Wu KC | Circulation. Arrhythmia and electrophysiology | 32188287 | Circ Arrhythm Electrophysiol | 2020 Apr |
Characterization of the Electrophysiologic Remodeling of Patients With Ischemic Cardiomyopathy by Clinical Measurements and Computer Simulations Coupled With Machine Learning. | Aronis KN, Prakosa A, Bergamaschi T, Berger RD, Boyle PM, Chrispin J, Ju S, Marine JE, Sinha S, Tandri H, Ashikaga H, Trayanova NA | Frontiers in physiology | 34335294 | Front Physiol | 2021 |
Optimizing cardiac resynchronization therapy to minimize ATP consumption heterogeneity throughout the left ventricle: a simulation analysis using a canine heart failure model. | Hu Y, Gurev V, Constantino J, Trayanova N | Heart rhythm | 24657430 | Heart Rhythm | 2014 Jun |
Early somatic mosaicism is a rare cause of long-QT syndrome. | Priest JR, Gawad C, Kahlig KM, Yu JK, O'Hara T, Boyle PM, Rajamani S, Clark MJ, Garcia ST, Ceresnak S, Harris J, Boyle S, Dewey FE, Malloy-Walton L, Dunn K, Grove M, Perez MV, Neff NF, Chen R, Maeda K, Dubin A, Belardinelli L, West J, Antolik C, Macaya D, Quertermous T, Trayanova NA, Quake SR, Ashley EA | Proceedings of the National Academy of Sciences of the United States of America | 27681629 | Proc Natl Acad Sci U S A | 2016 Oct 11 |
Sodium current reduction unmasks a structure-dependent substrate for arrhythmogenesis in the normal ventricles. | Boyle PM, Park CJ, Arevalo HJ, Vigmond EJ, Trayanova NA | PloS one | 24489810 | PLoS One | 2014 |
Advances in modeling ventricular arrhythmias: from mechanisms to the clinic. | Trayanova NA, Boyle PM | Wiley interdisciplinary reviews. Systems biology and medicine | 24375958 | Wiley Interdiscip Rev Syst Biol Med | 2014 Mar-Apr |
Methodology for image-based reconstruction of ventricular geometry for patient-specific modeling of cardiac electrophysiology. | Prakosa A, Malamas P, Zhang S, Pashakhanloo F, Arevalo H, Herzka DA, Lardo A, Halperin H, McVeigh E, Trayanova N, Vadakkumpadan F | Progress in biophysics and molecular biology | 25148771 | Prog Biophys Mol Biol | 2014 Aug |
Image-based left ventricular shape analysis for sudden cardiac death risk stratification. | Vadakkumpadan F, Trayanova N, Wu KC | Heart rhythm | 24854217 | Heart Rhythm | 2014 Oct |
Disrupted calcium release as a mechanism for atrial alternans associated with human atrial fibrillation. | Chang KC, Bayer JD, Trayanova NA | PLoS computational biology | 25501557 | PLoS Comput Biol | 2014 Dec |
Virtual electrophysiological study of atrial fibrillation in fibrotic remodeling. | McDowell KS, Zahid S, Vadakkumpadan F, Blauer J, MacLeod RS, Trayanova NA | PloS one | 25692857 | PLoS One | 2015 |
Mechanisms of arrhythmogenesis related to calcium-driven alternans in a model of human atrial fibrillation. | Chang KC, Trayanova NA | Scientific reports | 27812021 | Sci Rep | 2016 Nov 4 |
Sensitivity of Ablation Targets Prediction to Electrophysiological Parameter Variability in Image-Based Computational Models of Ventricular Tachycardia in Post-infarction Patients. | Deng D, Prakosa A, Shade J, Nikolov P, Trayanova NA | Frontiers in physiology | 31178758 | Front Physiol | 2019 |
Personalized virtual-heart technology for guiding the ablation of infarct-related ventricular tachycardia. | Prakosa A, Arevalo HJ, Deng D, Boyle PM, Nikolov PP, Ashikaga H, Blauer JJE, Ghafoori E, Park CJ, Blake RC 3rd, Han FT, MacLeod RS, Halperin HR, Callans DJ, Ranjan R, Chrispin J, Nazarian S, Trayanova NA | Nature biomedical engineering | 30847259 | Nat Biomed Eng | 2018 Oct |
Quantifying the uncertainty in model parameters using Gaussian process-based Markov chain Monte Carlo in cardiac electrophysiology. | Dhamala J, Arevalo HJ, Sapp J, Horácek BM, Wu KC, Trayanova NA, Wang L | Medical image analysis | 29843078 | Med Image Anal | 2018 Aug |
Relationship Between Fibrosis Detected on Late Gadolinium-Enhanced Cardiac Magnetic Resonance and Re-Entrant Activity Assessed With Electrocardiographic Imaging in Human Persistent Atrial Fibrillation. | Cochet H, Dubois R, Yamashita S, Al Jefairi N, Berte B, Sellal JM, Hooks D, Frontera A, Amraoui S, Zemoura A, Denis A, Derval N, Sacher F, Corneloup O, Latrabe V, Clément-Guinaudeau S, Relan J, Zahid S, Boyle PM, Trayanova NA, Bernus O, Montaudon M, Laurent F, Hocini M, Haïssaguerre M, Jaïs P | JACC. Clinical electrophysiology | 29479568 | JACC Clin Electrophysiol | 2018 Jan |
Increased thin filament activation enhances alternans in human chronic atrial fibrillation. | Zile MA, Trayanova NA | American journal of physiology. Heart and circulatory physiology | 30141984 | Am J Physiol Heart Circ Physiol | 2018 Nov 1 |
Modeling the aging heart: from local respiratory defects to global rhythm disturbances. | Khrapko K, Trayanova N, Nattel S | Cell metabolism | 25955202 | Cell Metab | 2015 May 5 |
Personalized Imaging and Modeling Strategies for Arrhythmia Prevention and Therapy. | Trayanova NA, Boyle PM, Nikolov PP | Current opinion in biomedical engineering | 29546250 | Curr Opin Biomed Eng | 2018 Mar |
A comprehensive, multiscale framework for evaluation of arrhythmias arising from cell therapy in the whole post-myocardial infarcted heart. | Yu JK, Franceschi W, Huang Q, Pashakhanloo F, Boyle PM, Trayanova NA | Scientific reports | 31239508 | Sci Rep | 2019 Jun 25 |
New insights on the cardiac safety factor: Unraveling the relationship between conduction velocity and robustness of propagation. | Boyle PM, Franceschi WH, Constantin M, Hawks C, Desplantez T, Trayanova NA, Vigmond EJ | Journal of molecular and cellular cardiology | 30677394 | J Mol Cell Cardiol | 2019 Mar |
The role of personalized atrial modeling in understanding atrial fibrillation mechanisms and improving treatment. | Aronis KN, Ali R, Trayanova NA | International journal of cardiology | 30755334 | Int J Cardiol | 2019 Jul 15 |
β-adrenergic stimulation augments transmural dispersion of repolarization via modulation of delayed rectifier currents I(Ks) and I(Kr) in the human ventricle. | Kang C, Badiceanu A, Brennan JA, Gloschat C, Qiao Y, Trayanova NA, Efimov IR | Scientific reports | 29162896 | Sci Rep | 2017 Nov 21 |
Using personalized computer models to custom-tailor ablation procedures for atrial fibrillation patients: are we there yet? | Boyle PM, Zahid S, Trayanova NA | Expert review of cardiovascular therapy | 28395557 | Expert Rev Cardiovasc Ther | 2017 May |
Imaging-Based Simulations for Predicting Sudden Death and Guiding Ventricular Tachycardia Ablation. | Trayanova NA, Pashakhanloo F, Wu KC, Halperin HR | Circulation. Arrhythmia and electrophysiology | 28696219 | Circ Arrhythm Electrophysiol | 2017 Jul |
Modelling methodology of atrial fibrosis affects rotor dynamics and electrograms. | Roney CH, Bayer JD, Zahid S, Meo M, Boyle PM, Trayanova NA, Haïssaguerre M, Dubois R, Cochet H, Vigmond EJ | Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology | 28011842 | Europace | 2016 Dec |
Myofilament protein dynamics modulate EAD formation in human hypertrophic cardiomyopathy. | Zile MA, Trayanova NA | Progress in biophysics and molecular biology | 28648627 | Prog Biophys Mol Biol | 2017 Nov |
4D cardiac electromechanical activation imaging. | Grondin J, Wang D, Grubb CS, Trayanova N, Konofagou EE | Computers in biology and medicine | 31476587 | Comput Biol Med | 2019 Oct |
Characterizing Conduction Channels in Postinfarction Patients Using a Personalized Virtual Heart. | Deng D, Prakosa A, Shade J, Nikolov P, Trayanova NA | Biophysical journal | 31447108 | Biophys J | 2019 Dec 17 |
Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling. | Wright PT, Nikolaev VO, O'Hara T, Diakonov I, Bhargava A, Tokar S, Schobesberger S, Shevchuk AI, Sikkel MB, Wilkinson R, Trayanova NA, Lyon AR, Harding SE, Gorelik J | Journal of molecular and cellular cardiology | 24345421 | J Mol Cell Cardiol | 2014 Feb |
Corrigendum to "effects of fibrosis morphology on reentrant ventricular tachycardia inducibility and simulation fidelity in patient-derived models". | Ringenberg J, Deo M, Filgueiras-Rama D, Pizarro G, Ibañez B, Peinado R, Trayanova N, Miller M, Merino JL, Berenfeld O, Devabhaktuni V | Clinical Medicine Insights. Cardiology | 25698881 | Clin Med Insights Cardiol | 2014 |
Image-based reconstruction of three-dimensional myocardial infarct geometry for patient-specific modeling of cardiac electrophysiology. | Ukwatta E, Arevalo H, Rajchl M, White J, Pashakhanloo F, Prakosa A, Herzka DA, McVeigh E, Lardo AC, Trayanova NA, Vadakkumpadan F | Medical physics | 26233186 | Med Phys | 2015 Aug |
Rate-dependent force, intracellular calcium, and action potential voltage alternans are modulated by sarcomere length and heart failure induced-remodeling of thin filament regulation in human heart failure: A myocyte modeling study. | Zile MA, Trayanova NA | Progress in biophysics and molecular biology | 26724571 | Prog Biophys Mol Biol | 2016 Jan |
Image-based Reconstruction of 3D Myocardial Infarct Geometry for Patient Specific Applications. | Ukwatta E, Rajchl M, White J, Pashakhanloo F, Herzka DA, McVeigh E, Lardo AC, Trayanova N, Vadakkumpadan F | Proceedings of SPIE--the International Society for Optical Engineering | 26633913 | Proc SPIE Int Soc Opt Eng | 2015 Feb 21 |
How computer simulations of the human heart can improve anti-arrhythmia therapy. | Trayanova NA, Chang KC | The Journal of physiology | 26621489 | J Physiol | 2016 May 1 |
Association of Left Atrial Local Conduction Velocity With Late Gadolinium Enhancement on Cardiac Magnetic Resonance in Patients With Atrial Fibrillation. | Fukumoto K, Habibi M, Ipek EG, Zahid S, Khurram IM, Zimmerman SL, Zipunnikov V, Spragg D, Ashikaga H, Trayanova N, Tomaselli GF, Rickard J, Marine JE, Berger RD, Calkins H, Nazarian S | Circulation. Arrhythmia and electrophysiology | 26917814 | Circ Arrhythm Electrophysiol | 2016 Mar |
Submillimeter diffusion tensor imaging and late gadolinium enhancement cardiovascular magnetic resonance of chronic myocardial infarction. | Pashakhanloo F, Herzka DA, Mori S, Zviman M, Halperin H, Gai N, Bluemke DA, Trayanova NA, McVeigh ER | Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance | 28122618 | J Cardiovasc Magn Reson | 2017 Jan 11 |
Sensitivity of reentrant driver localization to electrophysiological parameter variability in image-based computational models of persistent atrial fibrillation sustained by a fibrotic substrate. | Deng D, Murphy MJ, Hakim JB, Franceschi WH, Zahid S, Pashakhanloo F, Trayanova NA, Boyle PM | Chaos (Woodbury, N.Y.) | 28964164 | Chaos | 2017 Sep |
Optogenetic defibrillation terminates ventricular arrhythmia in mouse hearts and human simulations. | Bruegmann T, Boyle PM, Vogt CC, Karathanos TV, Arevalo HJ, Fleischmann BK, Trayanova NA, Sasse P | The Journal of clinical investigation | 27617859 | J Clin Invest | 2016 Oct 3 |
Avian intervertebral disc arises from rostral sclerotome and lacks a nucleus pulposus: implications for evolution of the vertebrate disc. | Bruggeman BJ, Maier JA, Mohiuddin YS, Powers R, Lo Y, Guimarães-Camboa N, Evans SM, Harfe BD | Developmental dynamics : an official publication of the American Association of Anatomists | 22354863 | Dev Dyn | 2012 Apr |
Chronic centrosome amplification without tumorigenesis. | Vitre B, Holland AJ, Kulukian A, Shoshani O, Hirai M, Wang Y, Maldonado M, Cho T, Boubaker J, Swing DA, Tessarollo L, Evans SM, Fuchs E, Cleveland DW | Proceedings of the National Academy of Sciences of the United States of America | 26578792 | Proc Natl Acad Sci U S A | 2015 Nov 17 |
Coordination of heart and lung co-development by a multipotent cardiopulmonary progenitor. | Peng T, Tian Y, Boogerd CJ, Lu MM, Kadzik RS, Stewart KM, Evans SM, Morrisey EE | Nature | 23873040 | Nature | 2013 Aug 29 |
Mapping the dynamic expression of Wnt11 and the lineage contribution of Wnt11-expressing cells during early mouse development. | Sinha T, Lin L, Li D, Davis J, Evans S, Wynshaw-Boris A, Wang J | Developmental biology | 25448697 | Dev Biol | 2015 Feb 15 |
Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis. | Moore-Morris T, Guimarães-Camboa N, Banerjee I, Zambon AC, Kisseleva T, Velayoudon A, Stallcup WB, Gu Y, Dalton ND, Cedenilla M, Gomez-Amaro R, Zhou B, Brenner DA, Peterson KL, Chen J, Evans SM | The Journal of clinical investigation | 24937432 | J Clin Invest | 2014 Jul |
Sorting out where fibroblasts come from. | Moore-Morris T, Tallquist MD, Evans SM | Circulation research | 25214570 | Circ Res | 2014 Sep 12 |
Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. | Bolt CC, Negi S, Guimarães-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L | PloS one | 27120339 | PLoS One | 2016 |
Thymosin beta 4 is dispensable for murine cardiac development and function. | Banerjee I, Zhang J, Moore-Morris T, Lange S, Shen T, Dalton ND, Gu Y, Peterson KL, Evans SM, Chen J | Circulation research | 22158707 | Circ Res | 2012 Feb 3 |
Early postmyocardial infarction survival in Murphy Roths Large mice is mediated by attenuated apoptosis and inflammation but depends on genetic background. | Hunt DL, Campbell PH, Zambon AC, Vranizan K, Evans SM, Kuo HC, Yamaguchi KD, Omens JH, McCulloch AD | Experimental physiology | 21967898 | Exp Physiol | 2012 Jan |
Human pre-valvular endocardial cells derived from pluripotent stem cells recapitulate cardiac pathophysiological valvulogenesis. | Neri T, Hiriart E, van Vliet PP, Faure E, Norris RA, Farhat B, Jagla B, Lefrancois J, Sugi Y, Moore-Morris T, Zaffran S, Faustino RS, Zambon AC, Desvignes JP, Salgado D, Levine RA, de la Pompa JL, Terzic A, Evans SM, Markwald R, Pucéat M | Nature communications | 31028265 | Nat Commun | 2019 Apr 26 |
Transcription factor ISL1 is essential for pacemaker development and function. | Liang X, Zhang Q, Cattaneo P, Zhuang S, Gong X, Spann NJ, Jiang C, Cao X, Zhao X, Zhang X, Bu L, Wang G, Chen HS, Zhuang T, Yan J, Geng P, Luo L, Banerjee I, Chen Y, Glass CK, Zambon AC, Chen J, Sun Y, Evans SM | The Journal of clinical investigation | 26193633 | J Clin Invest | 2015 Aug 3 |
Origins of cardiac fibroblasts. | Moore-Morris T, Cattaneo P, Puceat M, Evans SM | Journal of molecular and cellular cardiology | 26748307 | J Mol Cell Cardiol | 2016 Feb |
Probing chromatin landscape reveals roles of endocardial TBX20 in septation. | Boogerd CJ, Aneas I, Sakabe N, Dirschinger RJ, Cheng QJ, Zhou B, Chen J, Nobrega MA, Evans SM | The Journal of clinical investigation | 27348591 | J Clin Invest | 2016 Aug 1 |
Single-molecule states link transcription factor binding to gene expression. | Doughty BR, Hinks MM, Schaepe JM, Marinov GK, Thurm AR, Rios-Martinez C, Parks BE, Tan Y, Marklund E, Dubocanin D, Bintu L, Greenleaf WJ | Nature | 39567683 | Nature | 2024 Dec |
Multiplex assessment of protein variant abundance by massively parallel sequencing. | Matreyek KA, Starita LM, Stephany JJ, Martin B, Chiasson MA, Gray VE, Kircher M, Khechaduri A, Dines JN, Hause RJ, Bhatia S, Evans WE, Relling MV, Yang W, Shendure J, Fowler DM | Nature genetics | 29785012 | Nat Genet | 2018 Jun |
The single-cell transcriptional landscape of mammalian organogenesis. | Cao J, Spielmann M, Qiu X, Huang X, Ibrahim DM, Hill AJ, Zhang F, Mundlos S, Christiansen L, Steemers FJ, Trapnell C, Shendure J | Nature | 30787437 | Nature | 2019 Feb |
Sci-Hi-C: A single-cell Hi-C method for mapping 3D genome organization in large number of single cells. | Ramani V, Deng X, Qiu R, Lee C, Disteche CM, Noble WS, Shendure J, Duan Z | Methods (San Diego, Calif.) | 31536770 | Methods | 2020 Jan 1 |
Saturation editing of genomic regions by multiplex homology-directed repair. | Findlay GM, Boyle EA, Hause RJ, Klein JC, Shendure J | Nature | 25141179 | Nature | 2014 Sep 4 |
Mapping 3D genome architecture through in situ DNase Hi-C. | Ramani V, Cusanovich DA, Hause RJ, Ma W, Qiu R, Deng X, Blau CA, Disteche CM, Noble WS, Shendure J, Duan Z | Nature protocols | 27685100 | Nat Protoc | 2016 Nov |
The power of multiplexed functional analysis of genetic variants. | Gasperini M, Starita L, Shendure J | Nature protocols | 27583640 | Nat Protoc | 2016 Oct |
Comprehensive single-cell transcriptional profiling of a multicellular organism. | Cao J, Packer JS, Ramani V, Cusanovich DA, Huynh C, Daza R, Qiu X, Lee C, Furlan SN, Steemers FJ, Adey A, Waterston RH, Trapnell C, Shendure J | Science (New York, N.Y.) | 28818938 | Science | 2017 Aug 18 |
Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain. | Raj B, Wagner DE, McKenna A, Pandey S, Klein AM, Shendure J, Gagnon JA, Schier AF | Nature biotechnology | 29608178 | Nat Biotechnol | 2018 Jun |
Cell-free DNA Comprises an In Vivo Nucleosome Footprint that Informs Its Tissues-Of-Origin. | Snyder MW, Kircher M, Hill AJ, Daza RM, Shendure J | Cell | 26771485 | Cell | 2016 Jan 14 |
The landscape of alternative polyadenylation in single cells of the developing mouse embryo. | Agarwal V, Lopez-Darwin S, Kelley DR, Shendure J | Nature communications | 34429411 | Nat Commun | 2021 Aug 24 |
FlashFry: a fast and flexible tool for large-scale CRISPR target design. | McKenna A, Shendure J | BMC biology | 29976198 | BMC Biol | 2018 Jul 5 |
Joint profiling of chromatin accessibility and gene expression in thousands of single cells. | Cao J, Cusanovich DA, Ramani V, Aghamirzaie D, Pliner HA, Hill AJ, Daza RM, McFaline-Figueroa JL, Packer JS, Christiansen L, Steemers FJ, Adey AC, Trapnell C, Shendure J | Science (New York, N.Y.) | 30166440 | Science | 2018 Sep 28 |
High-throughput determination of RNA structure by proximity ligation. | Ramani V, Qiu R, Shendure J | Nature biotechnology | 26237516 | Nat Biotechnol | 2015 Sep |
Multiplex single cell profiling of chromatin accessibility by combinatorial cellular indexing. | Cusanovich DA, Daza R, Adey A, Pliner HA, Christiansen L, Gunderson KL, Steemers FJ, Trapnell C, Shendure J | Science (New York, N.Y.) | 25953818 | Science | 2015 May 22 |
Massively parallel single-amino-acid mutagenesis. | Kitzman JO, Starita LM, Lo RS, Fields S, Shendure J | Nature methods | 25559584 | Nat Methods | 2015 Mar |
High Sensitivity Profiling of Chromatin Structure by MNase-SSP. | Ramani V, Qiu R, Shendure J | Cell reports | 30811994 | Cell Rep | 2019 Feb 26 |
Variant Interpretation: Functional Assays to the Rescue. | Starita LM, Ahituv N, Dunham MJ, Kitzman JO, Roth FP, Seelig G, Shendure J, Fowler DM | American journal of human genetics | 28886340 | Am J Hum Genet | 2017 Sep 7 |
CRISPR/Cas9-Mediated Scanning for Regulatory Elements Required for HPRT1 Expression via Thousands of Large, Programmed Genomic Deletions. | Gasperini M, Findlay GM, McKenna A, Milbank JH, Lee C, Zhang MD, Cusanovich DA, Shendure J | American journal of human genetics | 28712454 | Am J Hum Genet | 2017 Aug 3 |
High-Throughput Single-Cell Sequencing with Linear Amplification. | Yin Y, Jiang Y, Lam KG, Berletch JB, Disteche CM, Noble WS, Steemers FJ, Camerini-Otero RD, Adey AC, Shendure J | Molecular cell | 31495564 | Mol Cell | 2019 Nov 21 |
Cicero Predicts cis-Regulatory DNA Interactions from Single-Cell Chromatin Accessibility Data. | Pliner HA, Packer JS, McFaline-Figueroa JL, Cusanovich DA, Daza RM, Aghamirzaie D, Srivatsan S, Qiu X, Jackson D, Minkina A, Adey AC, Steemers FJ, Shendure J, Trapnell C | Molecular cell | 30078726 | Mol Cell | 2018 Sep 6 |
Supervised classification enables rapid annotation of cell atlases. | Pliner HA, Shendure J, Trapnell C | Nature methods | 31501545 | Nat Methods | 2019 Oct |
Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy. | McFaline-Figueroa JL, Srivatsan S, Hill AJ, Gasperini M, Jackson DL, Saunders L, Domcke S, Regalado SG, Lazarchuck P, Alvarez S, Monnat RJ Jr, Shendure J, Trapnell C | Cell genomics | 38278156 | Cell Genom | 2024 Feb 14 |
Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy. | McFaline-Figueroa JL, Srivatsan S, Hill AJ, Gasperini M, Jackson DL, Saunders L, Domcke S, Regalado SG, Lazarchuck P, Alvarez S, Monnat RJ Jr, Shendure J, Trapnell C | bioRxiv : the preprint server for biology | 37398090 | bioRxiv | 2023 Jun 14 |
Accurate classification of BRCA1 variants with saturation genome editing. | Findlay GM, Daza RM, Martin B, Zhang MD, Leith AP, Gasperini M, Janizek JD, Huang X, Starita LM, Shendure J | Nature | 30209399 | Nature | 2018 Oct |
Multimodal single-cell analysis reveals distinct radioresistant stem-like and progenitor cell populations in murine glioma. | Alexander J, LaPlant QC, Pattwell SS, Szulzewsky F, Cimino PJ, Caruso FP, Pugliese P, Chen Z, Chardon F, Hill AJ, Spurrell C, Ahrendsen D, Pietras A, Starita LM, Hambardzumyan D, Iavarone A, Shendure J, Holland EC | Glia | 32621641 | Glia | 2020 Dec |
Predicting mRNA Abundance Directly from Genomic Sequence Using Deep Convolutional Neural Networks. | Agarwal V, Shendure J | Cell reports | 32433972 | Cell Rep | 2020 May 19 |
The cis-regulatory dynamics of embryonic development at single-cell resolution. | Cusanovich DA, Reddington JP, Garfield DA, Daza RM, Aghamirzaie D, Marco-Ferreres R, Pliner HA, Christiansen L, Qiu X, Steemers FJ, Trapnell C, Shendure J, Furlong EEM | Nature | 29539636 | Nature | 2018 Mar 22 |
Massively Parallel Functional Analysis of BRCA1 RING Domain Variants. | Starita LM, Young DL, Islam M, Kitzman JO, Gullingsrud J, Hause RJ, Fowler DM, Parvin JD, Shendure J, Fields S | Genetics | 25823446 | Genetics | 2015 Jun |
Quantitative Missense Variant Effect Prediction Using Large-Scale Mutagenesis Data. | Gray VE, Hause RJ, Luebeck J, Shendure J, Fowler DM | Cell systems | 29226803 | Cell Syst | 2018 Jan 24 |
Sci-fate characterizes the dynamics of gene expression in single cells. | Cao J, Zhou W, Steemers F, Trapnell C, Shendure J | Nature biotechnology | 32284584 | Nat Biotechnol | 2020 Aug |
Massively multiplex single-cell Hi-C. | Ramani V, Deng X, Qiu R, Gunderson KL, Steemers FJ, Disteche CM, Noble WS, Duan Z, Shendure J | Nature methods | 28135255 | Nat Methods | 2017 Mar |
On the design of CRISPR-based single-cell molecular screens. | Hill AJ, McFaline-Figueroa JL, Starita LM, Gasperini MJ, Matreyek KA, Packer J, Jackson D, Shendure J, Trapnell C | Nature methods | 29457792 | Nat Methods | 2018 Apr |
Genomic Medicine-Progress, Pitfalls, and Promise. | Shendure J, Findlay GM, Snyder MW | Cell | 30901547 | Cell | 2019 Mar 21 |
A Genome-wide Framework for Mapping Gene Regulation via Cellular Genetic Screens. | Gasperini M, Hill AJ, McFaline-Figueroa JL, Martin B, Kim S, Zhang MD, Jackson D, Leith A, Schreiber J, Noble WS, Trapnell C, Ahituv N, Shendure J | Cell | 30849375 | Cell | 2019 Mar 7 |
A Single-Cell Atlas of In Vivo Mammalian Chromatin Accessibility. | Cusanovich DA, Hill AJ, Aghamirzaie D, Daza RM, Pliner HA, Berletch JB, Filippova GN, Huang X, Christiansen L, DeWitt WS, Lee C, Regalado SG, Read DF, Steemers FJ, Disteche CM, Trapnell C, Shendure J | Cell | 30078704 | Cell | 2018 Aug 23 |
A Genome-wide Framework for Mapping Gene Regulation via Cellular Genetic Screens. | Gasperini M, Hill AJ, McFaline-Figueroa JL, Martin B, Kim S, Zhang MD, Jackson D, Leith A, Schreiber J, Noble WS, Trapnell C, Ahituv N, Shendure J | Cell | 30612741 | Cell | 2019 Jan 10 |
A Multiplex Homology-Directed DNA Repair Assay Reveals the Impact of More Than 1,000 BRCA1 Missense Substitution Variants on Protein Function. | Starita LM, Islam MM, Banerjee T, Adamovich AI, Gullingsrud J, Fields S, Shendure J, Parvin JD | American journal of human genetics | 30219179 | Am J Hum Genet | 2018 Oct 4 |
Whole-organism lineage tracing by combinatorial and cumulative genome editing. | McKenna A, Findlay GM, Gagnon JA, Horwitz MS, Schier AF, Shendure J | Science (New York, N.Y.) | 27229144 | Science | 2016 Jul 29 |
Massively multiplex chemical transcriptomics at single-cell resolution. | Srivatsan SR, McFaline-Figueroa JL, Ramani V, Saunders L, Cao J, Packer J, Pliner HA, Jackson DL, Daza RM, Christiansen L, Zhang F, Steemers F, Shendure J, Trapnell C | Science (New York, N.Y.) | 31806696 | Science | 2020 Jan 3 |
Concurrent genome and epigenome editing by CRISPR-mediated sequence replacement. | Alexander J, Findlay GM, Kircher M, Shendure J | BMC biology | 31739790 | BMC Biol | 2019 Nov 18 |
A general framework for estimating the relative pathogenicity of human genetic variants. | Kircher M, Witten DM, Jain P, O'Roak BJ, Cooper GM, Shendure J | Nature genetics | 24487276 | Nat Genet | 2014 Mar |
Copy-number variation and false positive prenatal aneuploidy screening results. | Snyder MW, Simmons LE, Kitzman JO, Coe BP, Henson JM, Daza RM, Eichler EE, Shendure J, Gammill HS | The New England journal of medicine | 25830323 | N Engl J Med | 2015 Apr 23 |
Spatial patterning of energy metabolism during tissue morphogenesis. | Lemma B, Nelson CM | Current opinion in cell biology | 37696131 | Curr Opin Cell Biol | 2023 Dec |
Plasticity in airway smooth muscle differentiation during mouse lung development. | Goodwin K, Lemma B, Zhang P, Boukind A, Nelson CM | Developmental cell | 36868232 | Dev Cell | 2023 Mar 13 |
Mesenchymal Vangl1 and Vangl2 facilitate airway elongation and widening independently of the planar cell polarity complex. | Paramore SV, Goodwin K, Fowler EW, Devenport D, Nelson CM | Development (Cambridge, England) | 39225402 | Development | 2024 Aug 15 |
Biophysics of morphogenesis in the vertebrate lung. | Banavar SP, Fowler EW, Nelson CM | Current topics in developmental biology | 38937031 | Curr Top Dev Biol | 2024 |
Analysis of Cre lines for targeting embryonic airway smooth muscle. | Goodwin K, Nelson CM | Developmental biology | 36706974 | Dev Biol | 2023 Apr |
Mesenchymal Vangl facilitates airway elongation and widening independently of the planar cell polarity complex. | Paramore SV, Goodwin K, Devenport D, Nelson CM | bioRxiv : the preprint server for biology | 37461477 | bioRxiv | 2023 Jul 3 |
Vangl-dependent mesenchymal thinning shapes the distal lung during murine sacculation. | Paramore SV, Trenado-Yuste C, Sharan R, Nelson CM, Devenport D | Developmental cell | 38569553 | Dev Cell | 2024 May 20 |
pYtags enable spatiotemporal measurements of receptor tyrosine kinase signaling in living cells. | Farahani PE, Yang X, Mesev EV, Fomby KA, Brumbaugh-Reed EH, Bashor CJ, Nelson CM, Toettcher JE | eLife | 37212240 | Elife | 2023 May 22 |
Integrin β1 coordinates survival and morphogenesis of the embryonic lineage upon implantation and pluripotency transition. | Molè MA, Weberling A, Fässler R, Campbell A, Fishel S, Zernicka-Goetz M | Cell reports | 33691117 | Cell Rep | 2021 Mar 9 |
Self-organization of stem cells into embryos: A window on early mammalian development. | Shahbazi MN, Siggia ED, Zernicka-Goetz M | Science (New York, N.Y.) | 31171690 | Science | 2019 Jun 7 |
Assembly of complete mouse embryo models from embryonic and induced stem cell types in vitro. | Lau KYC, Amadei G, Zernicka-Goetz M | Nature protocols | 37821625 | Nat Protoc | 2023 Dec |
Temporal BMP4 effects on mouse embryonic and extraembryonic development. | Hadas R, Rubinstein H, Mittnenzweig M, Mayshar Y, Ben-Yair R, Cheng S, Aguilera-Castrejon A, Reines N, Orenbuch AH, Lifshitz A, Chen DY, Elowitz MB, Zernicka-Goetz M, Hanna JH, Tanay A, Stelzer Y | Nature | 39294373 | Nature | 2024 Oct |
Embryo model completes gastrulation to neurulation and organogenesis. | Amadei G, Handford CE, Qiu C, De Jonghe J, Greenfeld H, Tran M, Martin BK, Chen DY, Aguilera-Castrejon A, Hanna JH, Elowitz MB, Hollfelder F, Shendure J, Glover DM, Zernicka-Goetz M | Nature | 36007540 | Nature | 2022 Oct |
An in vitro stem cell model of human epiblast and yolk sac interaction. | Mackinlay KM, Weatherbee BA, Souza Rosa V, Handford CE, Hudson G, Coorens T, Pereira LV, Behjati S, Vallier L, Shahbazi MN, Zernicka-Goetz M | eLife | 34403333 | Elife | 2021 Aug 17 |
Unifying synthetic embryology. | Cornwall-Scoones J, Zernicka-Goetz M | Developmental biology | 33753081 | Dev Biol | 2021 Jun |
Trophectoderm mechanics direct epiblast shape upon embryo implantation. | Weberling A, Zernicka-Goetz M | Cell reports | 33472064 | Cell Rep | 2021 Jan 19 |
Progress and challenges in stem cell biology. | Apostolou E, Blau H, Chien K, Lancaster MA, Tata PR, Trompouki E, Watt FM, Zeng YA, Zernicka-Goetz M | Nature cell biology | 36788378 | Nat Cell Biol | 2023 Feb |
Mouse embryo model derived exclusively from embryonic stem cells undergoes neurulation and heart development. | Lau KYC, Rubinstein H, Gantner CW, Hadas R, Amadei G, Stelzer Y, Zernicka-Goetz M | Cell stem cell | 36084657 | Cell Stem Cell | 2022 Oct 6 |
AI-based approach to dissect the variability of mouse stem cell-derived embryo models. | Caldarelli P, Deininger L, Zhao S, Panda P, Yang C, Mikut R, Zernicka-Goetz M | Nature communications | 39971935 | Nat Commun | 2025 Feb 19 |
Basement membrane remodelling regulates mouse embryogenesis. | Kyprianou C, Christodoulou N, Hamilton RS, Nahaboo W, Boomgaard DS, Amadei G, Migeotte I, Zernicka-Goetz M | Nature | 32523119 | Nature | 2020 Jun |
Inducible Stem-Cell-Derived Embryos Capture Mouse Morphogenetic Events In Vitro. | Amadei G, Lau KYC, De Jonghe J, Gantner CW, Sozen B, Chan C, Zhu M, Kyprianou C, Hollfelder F, Zernicka-Goetz M | Developmental cell | 33378662 | Dev Cell | 2021 Feb 8 |
BMP signalling is required for extra-embryonic ectoderm development during pre-to-post-implantation transition of the mouse embryo. | Sozen B, Demir N, Zernicka-Goetz M | Developmental biology | 33217407 | Dev Biol | 2021 Feb |
Stem-cell-based human and mouse embryo models. | Bao M, Cornwall-Scoones J, Zernicka-Goetz M | Current opinion in genetics & development | 35988317 | Curr Opin Genet Dev | 2022 Oct |
spinDrop: a droplet microfluidic platform to maximise single-cell sequencing information content. | De Jonghe J, Kaminski TS, Morse DB, Tabaka M, Ellermann AL, Kohler TN, Amadei G, Handford CE, Findlay GM, Zernicka-Goetz M, Teichmann SA, Hollfelder F | Nature communications | 37553326 | Nat Commun | 2023 Aug 8 |
Topical section: embryonic models (2023) for Current Opinion in Genetics & Development. | Handford CE, Junyent S, Jorgensen V, Zernicka-Goetz M | Current opinion in genetics & development | 38052116 | Curr Opin Genet Dev | 2024 Feb |
Principles of Self-Organization of the Mammalian Embryo. | Zhu M, Zernicka-Goetz M | Cell | 33306953 | Cell | 2020 Dec 10 |
Embryo size regulates the timing and mechanism of pluripotent tissue morphogenesis. | Orietti LC, Rosa VS, Antonica F, Kyprianou C, Mansfield W, Marques-Souza H, Shahbazi MN, Zernicka-Goetz M | Stem cell reports | 33035465 | Stem Cell Reports | 2021 May 11 |
The dynamics of morphogenesis in stem cell-based embryology: Novel insights for symmetry breaking. | Sozen B, Cornwall-Scoones J, Zernicka-Goetz M | Developmental biology | 33333067 | Dev Biol | 2021 Jun |
Modeling human embryo development with embryonic and extra-embryonic stem cells. | Weatherbee BAT, Cui T, Zernicka-Goetz M | Developmental biology | 33333069 | Dev Biol | 2021 Jun |
Self-Organization of Mouse Stem Cells into an Extended Potential Blastoid. | Sozen B, Cox AL, De Jonghe J, Bao M, Hollfelder F, Glover DM, Zernicka-Goetz M | Developmental cell | 31846649 | Dev Cell | 2019 Dec 16 |
Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tension. | Bao M, Cornwall-Scoones J, Sanchez-Vasquez E, Cox AL, Chen DY, De Jonghe J, Shadkhoo S, Hollfelder F, Thomson M, Glover DM, Zernicka-Goetz M | Nature cell biology | 36100738 | Nat Cell Biol | 2022 Sep |
Convergent Temperature Representations in Artificial and Biological Neural Networks. | Haesemeyer M, Schier AF, Engert F | Neuron | 31376984 | Neuron | 2019 Sep 25 |
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Cell-Specific Transcriptional Profiling of Ciliated Sensory Neurons Reveals Regulators of Behavior and Extracellular Vesicle Biogenesis. | Wang J, Kaletsky R, Silva M, Williams A, Haas LA, Androwski RJ, Landis JN, Patrick C, Rashid A, Santiago-Martinez D, Gravato-Nobre M, Hodgkin J, Hall DH, Murphy CT, Barr MM | Current biology : CB | 26687621 | Curr Biol | 2015 Dec 21 |
A natural bacterial pathogen of C. elegans uses a small RNA to induce transgenerational inheritance of learned avoidance. | Sengupta T, St Ange J, Moore R, Kaletsky R, Marogi J, Myhrvold C, Gitai Z, Murphy CT | bioRxiv : the preprint server for biology | 37503135 | bioRxiv | 2023 Oct 17 |
A natural bacterial pathogen of C. elegans uses a small RNA to induce transgenerational inheritance of learned avoidance. | Sengupta T, St Ange J, Kaletsky R, Moore RS, Seto RJ, Marogi J, Myhrvold C, Gitai Z, Murphy CT | PLoS genetics | 38547071 | PLoS Genet | 2024 Mar |
Systematic Comparison of Vesicular Targeting Signals Leads to the Development of Genetically Encoded Vesicular Fluorescent Zn(2+) and pH Sensors. | Pratt EPS, Anson KJ, Tapper JK, Simpson DM, Palmer AE | ACS sensors | 33305939 | ACS Sens | 2020 Dec 24 |
Characterization of Global Gene Expression, Regulation of Metal Ions, and Infection Outcomes in Immune-Competent 129S6 Mouse Macrophages. | Janiszewski LN, Minson M, Allen MA, Dowell RD, Palmer AE | Infection and immunity | 34370511 | Infect Immun | 2021 Oct 15 |
Techniques for measuring cellular zinc. | Carpenter MC, Lo MN, Palmer AE | Archives of biochemistry and biophysics | 27580940 | Arch Biochem Biophys | 2016 Dec 1 |
The Growing and Glowing Toolbox of Fluorescent and Photoactive Proteins. | Rodriguez EA, Campbell RE, Lin JY, Lin MZ, Miyawaki A, Palmer AE, Shu X, Zhang J, Tsien RY | Trends in biochemical sciences | 27814948 | Trends Biochem Sci | 2017 Feb |
Engineering of a Brighter Variant of the FusionRed Fluorescent Protein Using Lifetime Flow Cytometry and Structure-Guided Mutations. | Mukherjee S, Hung ST, Douglas N, Manna P, Thomas C, Ekrem A, Palmer AE, Jimenez R | Biochemistry | 32914619 | Biochemistry | 2020 Oct 6 |
Human cells experience a Zn(2+) pulse in early G1. | Rakshit A, Holtzen SE, Lo MN, Conway KA, Palmer AE | Cell reports | 37330912 | Cell Rep | 2023 Jun 27 |
Single molecule microscopy to profile the effect of zinc status on transcription factor dynamics. | Damon LJ, Aaron J, Palmer AE | Scientific reports | 36273101 | Sci Rep | 2022 Oct 22 |
Droplet Microfluidic Flow Cytometer For Sorting On Transient Cellular Responses Of Genetically-Encoded Sensors. | Fiedler BL, Van Buskirk S, Carter KP, Qin Y, Carpenter MC, Palmer AE, Jimenez R | Analytical chemistry | 27959493 | Anal Chem | 2017 Jan 3 |
Native and engineered sensors for Ca(2+) and Zn(2+): lessons from calmodulin and MTF1. | Carpenter MC, Palmer AE | Essays in biochemistry | 28487400 | Essays Biochem | 2017 May 9 |
Discovery of a ZIP7 inhibitor from a Notch pathway screen. | Nolin E, Gans S, Llamas L, Bandyopadhyay S, Brittain SM, Bernasconi-Elias P, Carter KP, Loureiro JJ, Thomas JR, Schirle M, Yang Y, Guo N, Roma G, Schuierer S, Beibel M, Lindeman A, Sigoillot F, Chen A, Xie KX, Ho S, Reece-Hoyes J, Weihofen WA, Tyskiewicz K, Hoepfner D, McDonald RI, Guthrie N, Dogra A, Guo H, Shao J, Ding J, Canham SM, Boynton G, George EL, Kang ZB, Antczak C, Porter JA, Wallace O, Tallarico JA, Palmer AE, Jenkins JL, Jain RK, Bushell SM, Fryer CJ | Nature chemical biology | 30643281 | Nat Chem Biol | 2019 Feb |
Intramolecular Fluorescent Protein Association in a Class of Zinc FRET Sensors Leads to Increased Dynamic Range. | Slocum JD, Palmer AE, Jimenez R | The journal of physical chemistry. B | 30942588 | J Phys Chem B | 2019 Apr 11 |
Zinc transporters belonging to the Cation Diffusion Facilitator (CDF) family have complementary roles in transporting zinc out of the cytosol. | Choi S, Hu YM, Corkins ME, Palmer AE, Bird AJ | PLoS genetics | 29529046 | PLoS Genet | 2018 Mar |
Dissociated Hippocampal Neurons Exhibit Distinct Zn(2+) Dynamics in a Stimulation-Method-Dependent Manner. | Sanford L, Palmer AE | ACS chemical neuroscience | 32013397 | ACS Chem Neurosci | 2020 Feb 19 |
Directed Evolution of a Bright Variant of mCherry: Suppression of Nonradiative Decay by Fluorescence Lifetime Selections. | Mukherjee S, Manna P, Hung ST, Vietmeyer F, Friis P, Palmer AE, Jimenez R | The journal of physical chemistry. B | 35709514 | J Phys Chem B | 2022 Jun 30 |
Illuminating RNA Biology: Tools for Imaging RNA in Live Mammalian Cells. | Braselmann E, Rathbun C, Richards EM, Palmer AE | Cell chemical biology | 32640188 | Cell Chem Biol | 2020 Aug 20 |
A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells. | Braselmann E, Palmer AE | Methods in enzymology | 32713529 | Methods Enzymol | 2020 |
Zn(2+) influx activates ERK and Akt signaling pathways. | Anson KJ, Corbet GA, Palmer AE | Proceedings of the National Academy of Sciences of the United States of America | 33712543 | Proc Natl Acad Sci U S A | 2021 Mar 16 |
Superiority of SpiroZin2 Versus FluoZin-3 for monitoring vesicular Zn(2+) allows tracking of lysosomal Zn(2+) pools. | Han Y, Goldberg JM, Lippard SJ, Palmer AE | Scientific reports | 30302024 | Sci Rep | 2018 Oct 9 |
Remodeling of Zn(2+) homeostasis upon differentiation of mammary epithelial cells. | Han Y, Sanford L, Simpson DM, Dowell RD, Palmer AE | Metallomics : integrated biometal science | 31950952 | Metallomics | 2020 Mar 25 |
Intracellular Zn(2+) transients modulate global gene expression in dissociated rat hippocampal neurons. | Sanford L, Carpenter MC, Palmer AE | Scientific reports | 31253848 | Sci Rep | 2019 Jun 28 |
Tools and techniques for illuminating the cell biology of zinc. | Pratt EPS, Damon LJ, Anson KJ, Palmer AE | Biochimica et biophysica acta. Molecular cell research | 32980354 | Biochim Biophys Acta Mol Cell Res | 2021 Jan |
A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells. | Braselmann E, Wierzba AJ, Polaski JT, Chromiński M, Holmes ZE, Hung ST, Batan D, Wheeler JR, Parker R, Jimenez R, Gryko D, Batey RT, Palmer AE | Nature chemical biology | 30061719 | Nat Chem Biol | 2018 Oct |
Directed evolution of excited state lifetime and brightness in FusionRed using a microfluidic sorter. | Manna P, Hung ST, Mukherjee S, Friis P, Simpson DM, Lo MN, Palmer AE, Jimenez R | Integrative biology : quantitative biosciences from nano to macro | 30094420 | Integr Biol (Camb) | 2018 Sep 17 |
Critical Comparison of FRET-Sensor Functionality in the Cytosol and Endoplasmic Reticulum and Implications for Quantification of Ions. | Carter KP, Carpenter MC, Fiedler B, Jimenez R, Palmer AE | Analytical chemistry | 28758723 | Anal Chem | 2017 Sep 5 |
A Critical and Comparative Review of Fluorescent Tools for Live-Cell Imaging. | Specht EA, Braselmann E, Palmer AE | Annual review of physiology | 27860833 | Annu Rev Physiol | 2017 Feb 10 |
Single cell analysis reveals multiple requirements for zinc in the mammalian cell cycle. | Lo MN, Damon LJ, Wei Tay J, Jia S, Palmer AE | eLife | 32014109 | Elife | 2020 Feb 4 |
Erratum: Directed evolution of excited state lifetime and brightness in FusionRed using a microfluidic sorter. | Manna P, Hung ST, Mukherjee S, Friis P, Simpson DM, Lo M, Palmer AE, Jimenez R | Integrative biology : quantitative biosciences from nano to macro | 31788687 | Integr Biol (Camb) | 2019 Dec 31 |
Zidovudine ameliorates pathology in the mouse model of Duchenne muscular dystrophy via P2RX7 purinoceptor antagonism. | Al-Khalidi R, Panicucci C, Cox P, Chira N, Róg J, Young CNJ, McGeehan RE, Ambati K, Ambati J, Zabłocki K, Gazzerro E, Arkle S, Bruno C, Górecki DC | Acta neuropathologica communications | 29642926 | Acta Neuropathol Commun | 2018 Apr 11 |
Intravenous immune globulin suppresses angiogenesis in mice and humans. | Yasuma R, Cicatiello V, Mizutani T, Tudisco L, Kim Y, Tarallo V, Bogdanovich S, Hirano Y, Kerur N, Li S, Yasuma T, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ambati BK, Helmers SB, Lundberg IE, Viklicky O, Leusen JH, Verbeek JS, Gelfand BD, Bastos-Carvalho A, De Falco S, Ambati J | Signal transduction and targeted therapy | 26925256 | Signal Transduct Target Ther | 2016 |
Powerful anti-tumor and anti-angiogenic activity of a new anti-vascular endothelial growth factor receptor 1 peptide in colorectal cancer models. | Cicatiello V, Apicella I, Tudisco L, Tarallo V, Formisano L, Sandomenico A, Kim Y, Bastos-Carvalho A, Orlandi A, Ambati J, Ruvo M, Bianco R, De Falco S | Oncotarget | 25868854 | Oncotarget | 2015 Apr 30 |
L1 drives IFN in senescent cells and promotes age-associated inflammation. | De Cecco M, Ito T, Petrashen AP, Elias AE, Skvir NJ, Criscione SW, Caligiana A, Brocculi G, Adney EM, Boeke JD, Le O, Beauséjour C, Ambati J, Ambati K, Simon M, Seluanov A, Gorbunova V, Slagboom PE, Helfand SL, Neretti N, Sedivy JM | Nature | 30728521 | Nature | 2019 Feb |
Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity. | Fowler BJ, Gelfand BD, Kim Y, Kerur N, Tarallo V, Hirano Y, Amarnath S, Fowler DH, Radwan M, Young MT, Pittman K, Kubes P, Agarwal HK, Parang K, Hinton DR, Bastos-Carvalho A, Li S, Yasuma T, Mizutani T, Yasuma R, Wright C, Ambati J | Science (New York, N.Y.) | 25414314 | Science | 2014 Nov 21 |
Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome. | Gelfand BD, Wright CB, Kim Y, Yasuma T, Yasuma R, Li S, Fowler BJ, Bastos-Carvalho A, Kerur N, Uittenbogaard A, Han YS, Lou D, Kleinman ME, McDonald WH, Núñez G, Georgel P, Dunaief JL, Ambati J | Cell reports | 26074074 | Cell Rep | 2015 Jun 23 |
IL-18 is not therapeutic for neovascular age-related macular degeneration. | Hirano Y, Yasuma T, Mizutani T, Fowler BJ, Tarallo V, Yasuma R, Kim Y, Bastos-Carvalho A, Kerur N, Gelfand BD, Bogdanovich S, He S, Zhang X, Nozaki M, Ijima R, Kaneko H, Ogura Y, Terasaki H, Nagai H, Haro I, Núñez G, Ambati BK, Hinton DR, Ambati J | Nature medicine | 25473914 | Nat Med | 2014 Dec |
RF/6A Chorioretinal Cells Do Not Display Key Endothelial Phenotypes. | Makin RD, Apicella I, Nagasaka Y, Kaneko H, Turner SD, Kerur N, Ambati J, Gelfand BD | Investigative ophthalmology & visual science | 30508043 | Invest Ophthalmol Vis Sci | 2018 Dec 3 |
A Revised Hemodynamic Theory of Age-Related Macular Degeneration. | Gelfand BD, Ambati J | Trends in molecular medicine | 27423265 | Trends Mol Med | 2016 Aug |
Voluntary Exercise Suppresses Choroidal Neovascularization in Mice. | Makin RD, Argyle D, Hirahara S, Nagasaka Y, Zhang M, Yan Z, Kerur N, Ambati J, Gelfand BD | Investigative ophthalmology & visual science | 32460310 | Invest Ophthalmol Vis Sci | 2020 May 11 |
cGAS drives noncanonical-inflammasome activation in age-related macular degeneration. | Kerur N, Fukuda S, Banerjee D, Kim Y, Fu D, Apicella I, Varshney A, Yasuma R, Fowler BJ, Baghdasaryan E, Marion KM, Huang X, Yasuma T, Hirano Y, Serbulea V, Ambati M, Ambati VL, Kajiwara Y, Ambati K, Hirahara S, Bastos-Carvalho A, Ogura Y, Terasaki H, Oshika T, Kim KB, Hinton DR, Leitinger N, Cambier JC, Buxbaum JD, Kenney MC, Jazwinski SM, Nagai H, Hara I, West AP, Fitzgerald KA, Sadda SR, Gelfand BD, Ambati J | Nature medicine | 29176737 | Nat Med | 2018 Jan |
Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration. | Fukuda S, Varshney A, Fowler BJ, Wang SB, Narendran S, Ambati K, Yasuma T, Magagnoli J, Leung H, Hirahara S, Nagasaka Y, Yasuma R, Apicella I, Pereira F, Makin RD, Magner E, Liu X, Sun J, Wang M, Baker K, Marion KM, Huang X, Baghdasaryan E, Ambati M, Ambati VL, Pandey A, Pandya L, Cummings T, Banerjee D, Huang P, Yerramothu P, Tolstonog GV, Held U, Erwin JA, Paquola ACM, Herdy JR, Ogura Y, Terasaki H, Oshika T, Darwish S, Singh RK, Mozaffari S, Bhattarai D, Kim KB, Hardin JW, Bennett CL, Hinton DR, Hanson TE, Röver C, Parang K, Kerur N, Liu J, Werner BC, Sutton SS, Sadda SR, Schumann GG, Gelfand BD, Gage FH, Ambati J | Proceedings of the National Academy of Sciences of the United States of America | 33526699 | Proc Natl Acad Sci U S A | 2021 Feb 9 |
Nucleoside Reverse Transcriptase Inhibitors Suppress Laser-Induced Choroidal Neovascularization in Mice. | Mizutani T, Fowler BJ, Kim Y, Yasuma R, Krueger LA, Gelfand BD, Ambati J | Investigative ophthalmology & visual science | 26529046 | Invest Ophthalmol Vis Sci | 2015 Nov |
Human IgG1 antibodies suppress angiogenesis in a target-independent manner. | Bogdanovich S, Kim Y, Mizutani T, Yasuma R, Tudisco L, Cicatiello V, Bastos-Carvalho A, Kerur N, Hirano Y, Baffi JZ, Tarallo V, Li S, Yasuma T, Arpitha P, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ruvo M, Sandomenico A, Nozaki M, Ijima R, Kaneko H, Ogura Y, Terasaki H, Ambati BK, Leusen JH, Langdon WY, Clark MR, Armour KL, Bruhns P, Verbeek JS, Gelfand BD, De Falco S, Ambati J | Signal transduction and targeted therapy | 26918197 | Signal Transduct Target Ther | 2016 |
DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs. | Wang SB, Narendran S, Hirahara S, Varshney A, Pereira F, Apicella I, Ambati M, Ambati VL, Yerramothu P, Ambati K, Nagasaka Y, Argyle D, Huang P, Baker KL, Marion KM, Gupta K, Liu B, Hinton DR, Canna SW, Sallam T, Sadda SR, Kerur N, Gelfand BD, Ambati J | Science immunology | 34860583 | Sci Immunol | 2021 Dec 3 |
Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice. | Wright CB, Uehara H, Kim Y, Yasuma T, Yasuma R, Hirahara S, Makin RD, Apicella I, Pereira F, Nagasaka Y, Narendran S, Fukuda S, Albuquerque R, Fowler BJ, Bastos-Carvalho A, Georgel P, Hatada I, Chang B, Kerur N, Ambati BK, Ambati J, Gelfand BD | Proceedings of the National Academy of Sciences of the United States of America | 31964819 | Proc Natl Acad Sci U S A | 2020 Feb 4 |
A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling. | Banerjee D, Langberg K, Abbas S, Odermatt E, Yerramothu P, Volaric M, Reidenbach MA, Krentz KJ, Rubinstein CD, Brautigan DL, Abbas T, Gelfand BD, Ambati J, Kerur N | Nature communications | 34707113 | Nat Commun | 2021 Oct 27 |
DICER1/Alu RNA dysmetabolism induces Caspase-8-mediated cell death in age-related macular degeneration. | Kim Y, Tarallo V, Kerur N, Yasuma T, Gelfand BD, Bastos-Carvalho A, Hirano Y, Yasuma R, Mizutani T, Fowler BJ, Li S, Kaneko H, Bogdanovich S, Ambati BK, Hinton DR, Hauswirth WW, Hakem R, Wright C, Ambati J | Proceedings of the National Academy of Sciences of the United States of America | 25349431 | Proc Natl Acad Sci U S A | 2014 Nov 11 |
Dry Age-Related Macular Degeneration Pharmacology. | Wright CB, Ambati J | Handbook of experimental pharmacology | 27900609 | Handb Exp Pharmacol | 2017 |
Optical control of cell signaling by single-chain photoswitchable kinases. | Zhou XX, Fan LZ, Li P, Shen K, Lin MZ | Science (New York, N.Y.) | 28232577 | Science | 2017 Feb 24 |
An orange calcium-modulated bioluminescent indicator for non-invasive activity imaging. | Oh Y, Park Y, Cho JH, Wu H, Paulk NK, Liu LX, Kim N, Kay MA, Wu JC, Lin MZ | Nature chemical biology | 30936501 | Nat Chem Biol | 2019 May |
Optobiology: optical control of biological processes via protein engineering. | Kim B, Lin MZ | Biochemical Society transactions | 24059506 | Biochem Soc Trans | 2013 Oct |
Investigating neuronal function with optically controllable proteins. | Zhou XX, Pan M, Lin MZ | Frontiers in molecular neuroscience | 26257603 | Front Mol Neurosci | 2015 |
Fluorescent indicators for simultaneous reporting of all four cell cycle phases. | Bajar BT, Lam AJ, Badiee RK, Oh YH, Chu J, Zhou XX, Kim N, Kim BB, Chung M, Yablonovitch AL, Cruz BF, Kulalert K, Tao JJ, Meyer T, Su XD, Lin MZ | Nature methods | 27798610 | Nat Methods | 2016 Dec |
Structure-guided wavelength tuning in far-red fluorescent proteins. | Ng HL, Lin MZ | Current opinion in structural biology | 27468111 | Curr Opin Struct Biol | 2016 Aug |
Photoswitchable fluorescent proteins: ten years of colorful chemistry and exciting applications. | Zhou XX, Lin MZ | Current opinion in chemical biology | 23876529 | Curr Opin Chem Biol | 2013 Aug |
Optical control of biological processes by light-switchable proteins. | Fan LZ, Lin MZ | Wiley interdisciplinary reviews. Developmental biology | 25858669 | Wiley Interdiscip Rev Dev Biol | 2015 Sep-Oct |
Quantitative Multiscale Cell Imaging in Controlled 3D Microenvironments. | Welf ES, Driscoll MK, Dean KM, Schäfer C, Chu J, Davidson MW, Lin MZ, Danuser G, Fiolka R | Developmental cell | 26906741 | Dev Cell | 2016 Feb 22 |
Genetically encoded indicators of neuronal activity. | Lin MZ, Schnitzer MJ | Nature neuroscience | 27571193 | Nat Neurosci | 2016 Aug 26 |
A Single-Chain Photoswitchable CRISPR-Cas9 Architecture for Light-Inducible Gene Editing and Transcription. | Zhou XX, Zou X, Chung HK, Gao Y, Liu Y, Qi LS, Lin MZ | ACS chemical biology | 28938067 | ACS Chem Biol | 2018 Feb 16 |
Optical regulation of endogenous RhoA reveals selection of cellular responses by signal amplitude. | Ju J, Lee HN, Ning L, Ryu H, Zhou XX, Chun H, Lee YW, Lee-Richerson AI, Jeong C, Lin MZ, Seong J | Cell reports | 35830815 | Cell Rep | 2022 Jul 12 |
Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action. | Yan Y, Liu Q, Zang X, Yuan S, Bat-Erdene U, Nguyen C, Gan J, Zhou J, Jacobsen SE, Tang Y | Nature | 29995859 | Nature | 2018 Jul |
A carbonate-forming Baeyer-Villiger monooxygenase. | Hu Y, Dietrich D, Xu W, Patel A, Thuss JA, Wang J, Yin WB, Qiao K, Houk KN, Vederas JC, Tang Y | Nature chemical biology | 24838010 | Nat Chem Biol | 2014 Jul |
The fumagillin biosynthetic gene cluster in Aspergillus fumigatus encodes a cryptic terpene cyclase involved in the formation of β-trans-bergamotene. | Lin HC, Chooi YH, Dhingra S, Xu W, Calvo AM, Tang Y | Journal of the American Chemical Society | 23488861 | J Am Chem Soc | 2013 Mar 27 |
Complexity generation in fungal polyketide biosynthesis: a spirocycle-forming P450 in the concise pathway to the antifungal drug griseofulvin. | Cacho RA, Chooi YH, Zhou H, Tang Y | ACS chemical biology | 23978092 | ACS Chem Biol | 2013 Oct 18 |
A cytochrome P450 serves as an unexpected terpene cyclase during fungal meroterpenoid biosynthesis. | Chooi YH, Hong YJ, Cacho RA, Tantillo DJ, Tang Y | Journal of the American Chemical Society | 24161266 | J Am Chem Soc | 2013 Nov 13 |
Methylation-dependent acyl transfer between polyketide synthase and nonribosomal peptide synthetase modules in fungal natural product biosynthesis. | Zou Y, Xu W, Tsunematsu Y, Tang M, Watanabe K, Tang Y | Organic letters | 25494235 | Org Lett | 2014 Dec 19 |
Understanding Programming of Fungal Iterative Polyketide Synthases: The Biochemical Basis for Regioselectivity by the Methyltransferase Domain in the Lovastatin Megasynthase. | Cacho RA, Thuss J, Xu W, Sanichar R, Gao Z, Nguyen A, Vederas JC, Tang Y | Journal of the American Chemical Society | 26630357 | J Am Chem Soc | 2015 Dec 23 |
Oxidative trans to cis Isomerization of Olefins in Polyketide Biosynthesis. | Yamamoto T, Tsunematsu Y, Hara K, Suzuki T, Kishimoto S, Kawagishi H, Noguchi H, Hashimoto H, Tang Y, Hotta K, Watanabe K | Angewandte Chemie (International ed. in English) | 27072782 | Angew Chem Int Ed Engl | 2016 May 17 |
Biosynthesis of the α-nitro-containing cyclic tripeptide psychrophilin. | Zhao M, Lin HC, Tang Y | The Journal of antibiotics | 26956794 | J Antibiot (Tokyo) | 2016 Jul |
Identification and Heterologous Production of a Benzoyl-Primed Tricarboxylic Acid Polyketide Intermediate from the Zaragozic Acid A Biosynthetic Pathway. | Liu N, Hung YS, Gao SS, Hang L, Zou Y, Chooi YH, Tang Y | Organic letters | 28605916 | Org Lett | 2017 Jul 7 |
Investigation of fungal iterative polyketide synthase functions using partially assembled intermediates. | Gao Z, Wang J, Norquay AK, Qiao K, Tang Y, Vederas JC | Journal of the American Chemical Society | 23356934 | J Am Chem Soc | 2013 Feb 6 |
Expanding the structural diversity of polyketides by exploring the cofactor tolerance of an inline methyltransferase domain. | Winter JM, Chiou G, Bothwell IR, Xu W, Garg NK, Luo M, Tang Y | Organic letters | 23837609 | Org Lett | 2013 Jul 19 |
Mechanism of the P450-Catalyzed Oxidative Cyclization in the Biosynthesis of Griseofulvin. | Grandner JM, Cacho RA, Tang Y, Houk KN | ACS catalysis | 28503354 | ACS Catal | 2016 Jul 1 |
Coordinated and Iterative Enzyme Catalysis in Fungal Polyketide Biosynthesis. | Hang L, Liu N, Tang Y | ACS catalysis | 28529817 | ACS Catal | 2016 Sep 2 |
Involvement of Lipocalin-like CghA in Decalin-Forming Stereoselective Intramolecular [4+2] Cycloaddition. | Sato M, Yagishita F, Mino T, Uchiyama N, Patel A, Chooi YH, Goda Y, Xu W, Noguchi H, Yamamoto T, Hotta K, Houk KN, Tang Y, Watanabe K | Chembiochem : a European journal of chemical biology | 26360642 | Chembiochem | 2015 Nov 2 |
Identification and characterization of the chaetoviridin and chaetomugilin gene cluster in Chaetomium globosum reveal dual functions of an iterative highly-reducing polyketide synthase. | Winter JM, Sato M, Sugimoto S, Chiou G, Garg NK, Tang Y, Watanabe K | Journal of the American Chemical Society | 23072467 | J Am Chem Soc | 2012 Oct 31 |
Discovery of cryptic polyketide metabolites from dermatophytes using heterologous expression in Aspergillus nidulans. | Yin WB, Chooi YH, Smith AR, Cacho RA, Hu Y, White TC, Tang Y | ACS synthetic biology | 23758576 | ACS Synth Biol | 2013 Nov 15 |
Fungal polyketide synthase product chain-length control by partnering thiohydrolase. | Zabala AO, Chooi YH, Choi MS, Lin HC, Tang Y | ACS chemical biology | 24845309 | ACS Chem Biol | 2014 Jul 18 |
Enzymatic one-step ring contraction for quinolone biosynthesis. | Kishimoto S, Hara K, Hashimoto H, Hirayama Y, Champagne PA, Houk KN, Tang Y, Watanabe K | Nature communications | 30026518 | Nat Commun | 2018 Jul 19 |
Enzyme-catalyzed cationic epoxide rearrangements in quinolone alkaloid biosynthesis. | Zou Y, Garcia-Borràs M, Tang MC, Hirayama Y, Li DH, Li L, Watanabe K, Houk KN, Tang Y | Nature chemical biology | 28114276 | Nat Chem Biol | 2017 Mar |
Production of New Cladosporin Analogues by Reconstitution of the Polyketide Synthases Responsible for the Biosynthesis of this Antimalarial Agent. | Cochrane RV, Sanichar R, Lambkin GR, Reiz B, Xu W, Tang Y, Vederas JC | Angewandte Chemie (International ed. in English) | 26783060 | Angew Chem Int Ed Engl | 2016 Jan 11 |
Biochemical Characterization of a Eukaryotic Decalin-Forming Diels-Alderase. | Li L, Yu P, Tang MC, Zou Y, Gao SS, Hung YS, Zhao M, Watanabe K, Houk KN, Tang Y | Journal of the American Chemical Society | 27960349 | J Am Chem Soc | 2016 Dec 14 |
Collaborative Biosynthesis of Maleimide- and Succinimide-Containing Natural Products by Fungal Polyketide Megasynthases. | Sato M, Dander JE, Sato C, Hung YS, Gao SS, Tang MC, Hang L, Winter JM, Garg NK, Watanabe K, Tang Y | Journal of the American Chemical Society | 28365998 | J Am Chem Soc | 2017 Apr 19 |
Structural basis of nonribosomal peptide macrocyclization in fungi. | Zhang J, Liu N, Cacho RA, Gong Z, Liu Z, Qin W, Tang C, Tang Y, Zhou J | Nature chemical biology | 27748753 | Nat Chem Biol | 2016 Dec |
Identification of the Pyranonigrin A Biosynthetic Gene Cluster by Genome Mining in Penicillium thymicola IBT 5891. | Tang MC, Zou Y, Yee D, Tang Y | AIChE journal. American Institute of Chemical Engineers | 31588145 | AIChE J | 2018 Dec |
Identification and characterization of the echinocandin B biosynthetic gene cluster from Emericella rugulosa NRRL 11440. | Cacho RA, Jiang W, Chooi YH, Walsh CT, Tang Y | Journal of the American Chemical Society | 22998630 | J Am Chem Soc | 2012 Oct 10 |
The fumagillin gene cluster, an example of hundreds of genes under veA control in Aspergillus fumigatus. | Dhingra S, Lind AL, Lin HC, Tang Y, Rokas A, Calvo AM | PloS one | 24116213 | PLoS One | 2013 |
Short pathways to complexity generation: fungal peptidyl alkaloid multicyclic scaffolds from anthranilate building blocks. | Walsh CT, Haynes SW, Ames BD, Gao X, Tang Y | ACS chemical biology | 23659680 | ACS Chem Biol | 2013 Jul 19 |
Elucidation of pseurotin biosynthetic pathway points to trans-acting C-methyltransferase: generation of chemical diversity. | Tsunematsu Y, Fukutomi M, Saruwatari T, Noguchi H, Hotta K, Tang Y, Watanabe K | Angewandte Chemie (International ed. in English) | 24939566 | Angew Chem Int Ed Engl | 2014 Aug 4 |
Elucidation of the concise biosynthetic pathway of the communesin indole alkaloids. | Lin HC, Chiou G, Chooi YH, McMahon TC, Xu W, Garg NK, Tang Y | Angewandte Chemie (International ed. in English) | 25571861 | Angew Chem Int Ed Engl | 2015 Mar 2 |
Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi. | Cacho RA, Tang Y, Chooi YH | Frontiers in microbiology | 25642215 | Front Microbiol | 2014 |
Genome Mining and Assembly-Line Biosynthesis of the UCS1025A Pyrrolizidinone Family of Fungal Alkaloids. | Li L, Tang MC, Tang S, Gao S, Soliman S, Hang L, Xu W, Ye T, Watanabe K, Tang Y | Journal of the American Chemical Society | 29373009 | J Am Chem Soc | 2018 Feb 14 |
Discovery of Unclustered Fungal Indole Diterpene Biosynthetic Pathways through Combinatorial Pathway Reassembly in Engineered Yeast. | Tang MC, Lin HC, Li D, Zou Y, Li J, Xu W, Cacho RA, Hillenmeyer ME, Garg NK, Tang Y | Journal of the American Chemical Society | 26469304 | J Am Chem Soc | 2015 Nov 4 |
Generation of complexity in fungal terpene biosynthesis: discovery of a multifunctional cytochrome P450 in the fumagillin pathway. | Lin HC, Tsunematsu Y, Dhingra S, Xu W, Fukutomi M, Chooi YH, Cane DE, Calvo AM, Watanabe K, Tang Y | Journal of the American Chemical Society | 24568283 | J Am Chem Soc | 2014 Mar 19 |
SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis. | Ohashi M, Liu F, Hai Y, Chen M, Tang MC, Yang Z, Sato M, Watanabe K, Houk KN, Tang Y | Nature | 28902839 | Nature | 2017 Sep 28 |
Reversible Product Release and Recapture by a Fungal Polyketide Synthase Using a Carnitine Acyltransferase Domain. | Hang L, Tang MC, Harvey CJB, Page CG, Li J, Hung YS, Liu N, Hillenmeyer ME, Tang Y | Angewandte Chemie (International ed. in English) | 28679030 | Angew Chem Int Ed Engl | 2017 Aug 1 |
P450-Mediated Coupling of Indole Fragments To Forge Communesin and Unnatural Isomers. | Lin HC, McMahon TC, Patel A, Corsello M, Simon A, Xu W, Zhao M, Houk KN, Garg NK, Tang Y | Journal of the American Chemical Society | 26963294 | J Am Chem Soc | 2016 Mar 30 |
Cyclization of fungal nonribosomal peptides by a terminal condensation-like domain. | Gao X, Haynes SW, Ames BD, Wang P, Vien LP, Walsh CT, Tang Y | Nature chemical biology | 22902615 | Nat Chem Biol | 2012 Oct |
EcdGHK are three tailoring iron oxygenases for amino acid building blocks of the echinocandin scaffold. | Jiang W, Cacho RA, Chiou G, Garg NK, Tang Y, Walsh CT | Journal of the American Chemical Society | 23451921 | J Am Chem Soc | 2013 Mar 20 |
Genome mining of a prenylated and immunosuppressive polyketide from pathogenic fungi. | Chooi YH, Fang J, Liu H, Filler SG, Wang P, Tang Y | Organic letters | 23368997 | Org Lett | 2013 Feb 15 |
Biosynthesis of fungal indole alkaloids. | Xu W, Gavia DJ, Tang Y | Natural product reports | 25180619 | Nat Prod Rep | 2014 Oct |
Phenalenone Polyketide Cyclization Catalyzed by Fungal Polyketide Synthase and Flavin-Dependent Monooxygenase. | Gao SS, Duan A, Xu W, Yu P, Hang L, Houk KN, Tang Y | Journal of the American Chemical Society | 26978228 | J Am Chem Soc | 2016 Mar 30 |
Thioesterase-Catalyzed Aminoacylation and Thiolation of Polyketides in Fungi. | Tang MC, Fischer CR, Chari JV, Tan D, Suresh S, Chu A, Miranda M, Smith J, Zhang Z, Garg NK, St Onge RP, Tang Y | Journal of the American Chemical Society | 31051070 | J Am Chem Soc | 2019 May 22 |
Combinatorial Generation of Chemical Diversity by Redox Enzymes in Chaetoviridin Biosynthesis. | Sato M, Winter JM, Kishimoto S, Noguchi H, Tang Y, Watanabe K | Organic letters | 26959241 | Org Lett | 2016 Mar 18 |
Epigenetic genome mining of an endophytic fungus leads to the pleiotropic biosynthesis of natural products. | Mao XM, Xu W, Li D, Yin WB, Chooi YH, Li YQ, Tang Y, Hu Y | Angewandte Chemie (International ed. in English) | 26013262 | Angew Chem Int Ed Engl | 2015 Jun 22 |
Biochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide Biosynthesis. | Winter JM, Cascio D, Dietrich D, Sato M, Watanabe K, Sawaya MR, Vederas JC, Tang Y | Journal of the American Chemical Society | 26172141 | J Am Chem Soc | 2015 Aug 12 |
Efficient Biosynthesis of Fungal Polyketides Containing the Dioxabicyclo-octane Ring System. | Mao XM, Zhan ZJ, Grayson MN, Tang MC, Xu W, Li YQ, Yin WB, Lin HC, Chooi YH, Houk KN, Tang Y | Journal of the American Chemical Society | 26340065 | J Am Chem Soc | 2015 Sep 23 |
Comparison of 10,11-Dehydrocurvularin Polyketide Synthases from Alternaria cinerariae and Aspergillus terreus Highlights Key Structural Motifs. | Cochrane RV, Gao Z, Lambkin GR, Xu W, Winter JM, Marcus SL, Tang Y, Vederas JC | Chembiochem : a European journal of chemical biology | 26493380 | Chembiochem | 2015 Nov |
Saccharomyces cerevisiae as a tool for mining, studying and engineering fungal polyketide synthases. | Bond C, Tang Y, Li L | Fungal genetics and biology : FG & B | 26850128 | Fungal Genet Biol | 2016 Apr |
Enzyme-Catalyzed Intramolecular Enantioselective Hydroalkoxylation. | Gao SS, Garcia-Borràs M, Barber JS, Hai Y, Duan A, Garg NK, Houk KN, Tang Y | Journal of the American Chemical Society | 28240554 | J Am Chem Soc | 2017 Mar 15 |
Tandem prenyltransferases catalyze isoprenoid elongation and complexity generation in biosynthesis of quinolone alkaloids. | Zou Y, Zhan Z, Li D, Tang M, Cacho RA, Watanabe K, Tang Y | Journal of the American Chemical Society | 25859931 | J Am Chem Soc | 2015 Apr 22 |
Biosynthesis of Strained Piperazine Alkaloids: Uncovering the Concise Pathway of Herquline A. | Yu X, Liu F, Zou Y, Tang MC, Hang L, Houk KN, Tang Y | Journal of the American Chemical Society | 27690412 | J Am Chem Soc | 2016 Oct 19 |
Investigating the Interplay between Sister Chromatid Cohesion and Homolog Pairing in Drosophila Nuclei. | Senaratne TN, Joyce EF, Nguyen SC, Wu CT | PLoS genetics | 27541002 | PLoS Genet | 2016 Aug |
3D mapping and accelerated super-resolution imaging of the human genome using in situ sequencing. | Nguyen HQ, Chattoraj S, Castillo D, Nguyen SC, Nir G, Lioutas A, Hershberg EA, Martins NMC, Reginato PL, Hannan M, Beliveau BJ, Church GM, Daugharthy ER, Marti-Renom MA, Wu CT | Nature methods | 32719531 | Nat Methods | 2020 Aug |
In Situ Super-Resolution Imaging of Genomic DNA with OligoSTORM and OligoDNA-PAINT. | Beliveau BJ, Boettiger AN, Nir G, Bintu B, Yin P, Zhuang X, Wu CT | Methods in molecular biology (Clifton, N.J.) | 28924672 | Methods Mol Biol | 2017 |
Genes with monoallelic expression contribute disproportionately to genetic diversity in humans. | Savova V, Chun S, Sohail M, McCole RB, Witwicki R, Gai L, Lenz TL, Wu CT, Sunyaev SR, Gimelbrant AA | Nature genetics | 26808112 | Nat Genet | 2016 Mar |
Germline progenitors escape the widespread phenomenon of homolog pairing during Drosophila development. | Joyce EF, Apostolopoulos N, Beliveau BJ, Wu CT | PLoS genetics | 24385920 | PLoS Genet | 2013 |
Single-molecule super-resolution imaging of chromosomes and in situ haplotype visualization using Oligopaint FISH probes. | Beliveau BJ, Boettiger AN, Avendaño MS, Jungmann R, McCole RB, Joyce EF, Kim-Kiselak C, Bantignies F, Fonseka CY, Erceg J, Hannan MA, Hoang HG, Colognori D, Lee JT, Shih WM, Yin P, Zhuang X, Wu CT | Nature communications | 25962338 | Nat Commun | 2015 May 12 |
Ultraconserved Elements Occupy Specific Arenas of Three-Dimensional Mammalian Genome Organization. | McCole RB, Erceg J, Saylor W, Wu CT | Cell reports | 29996107 | Cell Rep | 2018 Jul 10 |
Walking along chromosomes with super-resolution imaging, contact maps, and integrative modeling. | Nir G, Farabella I, Pérez Estrada C, Ebeling CG, Beliveau BJ, Sasaki HM, Lee SD, Nguyen SC, McCole RB, Chattoraj S, Erceg J, AlHaj Abed J, Martins NMC, Nguyen HQ, Hannan MA, Russell S, Durand NC, Rao SSP, Kishi JY, Soler-Vila P, Di Pierro M, Onuchic JN, Callahan SP, Schreiner JM, Stuckey JA, Yin P, Aiden EL, Marti-Renom MA, Wu CT | PLoS genetics | 30586358 | PLoS Genet | 2018 Dec |
A multiplexed DNA FISH strategy for assessing genome architecture in Caenorhabditis elegans. | Fields BD, Nguyen SC, Nir G, Kennedy S | eLife | 31084706 | Elife | 2019 May 14 |
Super-resolution imaging reveals distinct chromatin folding for different epigenetic states. | Boettiger AN, Bintu B, Moffitt JR, Wang S, Beliveau BJ, Fudenberg G, Imakaev M, Mirny LA, Wu CT, Zhuang X | Nature | 26760202 | Nature | 2016 Jan 21 |
Versatile design and synthesis platform for visualizing genomes with Oligopaint FISH probes. | Beliveau BJ, Joyce EF, Apostolopoulos N, Yilmaz F, Fonseka CY, McCole RB, Chang Y, Li JB, Senaratne TN, Williams BR, Rouillard JM, Wu CT | Proceedings of the National Academy of Sciences of the United States of America | 23236188 | Proc Natl Acad Sci U S A | 2012 Dec 26 |
Pairing and anti-pairing: a balancing act in the diploid genome. | Joyce EF, Erceg J, Wu CT | Current opinion in genetics & development | 27065367 | Curr Opin Genet Dev | 2016 Apr |
Islands of retroelements are major components of Drosophila centromeres. | Chang CH, Chavan A, Palladino J, Wei X, Martins NMC, Santinello B, Chen CC, Erceg J, Beliveau BJ, Wu CT, Larracuente AM, Mellone BG | PLoS biology | 31086362 | PLoS Biol | 2019 May |
Combined in vitro transcription and reverse transcription to amplify and label complex synthetic oligonucleotide probe libraries. | Murgha Y, Beliveau B, Semrau K, Schwartz D, Wu CT, Gulari E, Rouillard JM | BioTechniques | 26054766 | Biotechniques | 2015 Jun |
Scalable amplification of strand subsets from chip-synthesized oligonucleotide libraries. | Schmidt TL, Beliveau BJ, Uca YO, Theilmann M, Da Cruz F, Wu CT, Shih WM | Nature communications | 26567534 | Nat Commun | 2015 Nov 16 |
Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin. | Lee YCG, Ogiyama Y, Martins NMC, Beliveau BJ, Acevedo D, Wu CT, Cavalli G, Karpen GH | PLoS genetics | 32203508 | PLoS Genet | 2020 Mar |
Highly structured homolog pairing reflects functional organization of the Drosophila genome. | AlHaj Abed J, Erceg J, Goloborodko A, Nguyen SC, McCole RB, Saylor W, Fudenberg G, Lajoie BR, Dekker J, Mirny LA, Wu CT | Nature communications | 31582763 | Nat Commun | 2019 Oct 3 |
Spatial organization of chromatin domains and compartments in single chromosomes. | Wang S, Su JH, Beliveau BJ, Bintu B, Moffitt JR, Wu CT, Zhuang X | Science (New York, N.Y.) | 27445307 | Science | 2016 Aug 5 |
OligoMiner provides a rapid, flexible environment for the design of genome-scale oligonucleotide in situ hybridization probes. | Beliveau BJ, Kishi JY, Nir G, Sasaki HM, Saka SK, Nguyen SC, Wu CT, Yin P | Proceedings of the National Academy of Sciences of the United States of America | 29463736 | Proc Natl Acad Sci U S A | 2018 Mar 6 |
An Unexpected Regulatory Cascade Governs a Core Function of the Drosophila PRC1 Chromatin Protein Su(z)2. | Nguyen SC, Yu S, Oberlick E, Wu CT | Genetics | 27881472 | Genetics | 2017 Feb |
Visualizing genomes with Oligopaint FISH probes. | Beliveau BJ, Apostolopoulos N, Wu CT | Current protocols in molecular biology | 24510436 | Curr Protoc Mol Biol | 2014 Jan 6 |
Structures of TorsinA and its disease-mutant complexed with an activator reveal the molecular basis for primary dystonia. | Demircioglu FE, Sosa BA, Ingram J, Ploegh HL, Schwartz TU | eLife | 27490483 | Elife | 2016 Aug 4 |
Noninvasive Imaging of Human Immune Responses in a Human Xenograft Model of Graft-Versus-Host Disease. | Van Elssen CHMJ, Rashidian M, Vrbanac V, Wucherpfennig KW, Habre ZE, Sticht J, Freund C, Jacobsen JT, Cragnolini J, Ingram J, Plaisier L, Spierings E, Tager AM, Ploegh HL | Journal of nuclear medicine : official publication, Society of Nuclear Medicine | 28209904 | J Nucl Med | 2017 Jun |
Rapid capture and labeling of cells on single domain antibodies-functionalized flow cell. | Chen GY, Li Z, Duarte JN, Esteban A, Cheloha RW, Theile CS, Fink GR, Ploegh HL | Biosensors & bioelectronics | 27816596 | Biosens Bioelectron | 2017 Mar 15 |
Structurally Defined αMHC-II Nanobody-Drug Conjugates: A Therapeutic and Imaging System for B-Cell Lymphoma. | Fang T, Duarte JN, Ling J, Li Z, Guzman JS, Ploegh HL | Angewandte Chemie (International ed. in English) | 26840214 | Angew Chem Int Ed Engl | 2016 Feb 12 |
Crystal structure of a substrate-engaged SecY protein-translocation channel. | Li L, Park E, Ling J, Ingram J, Ploegh H, Rapoport TA | Nature | 26950603 | Nature | 2016 Mar 17 |
Localized CD47 blockade enhances immunotherapy for murine melanoma. | Ingram JR, Blomberg OS, Sockolosky JT, Ali L, Schmidt FI, Pishesha N, Espinosa C, Dougan SK, Garcia KC, Ploegh HL, Dougan M | Proceedings of the National Academy of Sciences of the United States of America | 28874561 | Proc Natl Acad Sci U S A | 2017 Sep 19 |
Antigen-specific B-cell receptor sensitizes B cells to infection by influenza virus. | Dougan SK, Ashour J, Karssemeijer RA, Popp MW, Avalos AM, Barisa M, Altenburg AF, Ingram JR, Cragnolini JJ, Guo C, Alt FW, Jaenisch R, Ploegh HL | Nature | 24141948 | Nature | 2013 Nov 21 |
How lamina-associated polypeptide 1 (LAP1) activates Torsin. | Sosa BA, Demircioglu FE, Chen JZ, Ingram J, Ploegh HL, Schwartz TU | eLife | 25149450 | Elife | 2014 Aug 22 |
Noninvasive imaging of immune responses. | Rashidian M, Keliher EJ, Bilate AM, Duarte JN, Wojtkiewicz GR, Jacobsen JT, Cragnolini J, Swee LK, Victora GD, Weissleder R, Ploegh HL | Proceedings of the National Academy of Sciences of the United States of America | 25902531 | Proc Natl Acad Sci U S A | 2015 May 12 |
Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells. | Rashidian M, Ingram JR, Dougan M, Dongre A, Whang KA, LeGall C, Cragnolini JJ, Bierie B, Gostissa M, Gorman J, Grotenbreg GM, Bhan A, Weinberg RA, Ploegh HL | The Journal of experimental medicine | 28666979 | J Exp Med | 2017 Aug 7 |
Anti-CTLA-4 therapy requires an Fc domain for efficacy. | Ingram JR, Blomberg OS, Rashidian M, Ali L, Garforth S, Fedorov E, Fedorov AA, Bonanno JB, Le Gall C, Crowley S, Espinosa C, Biary T, Keliher EJ, Weissleder R, Almo SC, Dougan SK, Ploegh HL, Dougan M | Proceedings of the National Academy of Sciences of the United States of America | 29581255 | Proc Natl Acad Sci U S A | 2018 Apr 10 |
The Antiviral Mechanism of an Influenza A Virus Nucleoprotein-Specific Single-Domain Antibody Fragment. | Hanke L, Knockenhauer KE, Brewer RC, van Diest E, Schmidt FI, Schwartz TU, Ploegh HL | mBio | 27965447 | mBio | 2016 Dec 13 |
Tissue-specific emergence of regulatory and intraepithelial T cells from a clonal T cell precursor. | Bilate AM, Bousbaine D, Mesin L, Agudelo M, Leube J, Kratzert A, Dougan SK, Victora GD, Ploegh HL | Science immunology | 28783695 | Sci Immunol | 2016 Aug 26 |
In vitro AMPylation Assays Using Purified, Recombinant Proteins. | Truttmann MC, Ploegh HL | Bio-protocol | 29170749 | Bio Protoc | 2017 Jul 20 |
Production of unnaturally linked chimeric proteins using a combination of sortase-catalyzed transpeptidation and click chemistry. | Witte MD, Theile CS, Wu T, Guimaraes CP, Blom AE, Ploegh HL | Nature protocols | 23989675 | Nat Protoc | 2013 Sep |
Allosteric activation of apicomplexan calcium-dependent protein kinases. | Ingram JR, Knockenhauer KE, Markus BM, Mandelbaum J, Ramek A, Shan Y, Shaw DE, Schwartz TU, Ploegh HL, Lourido S | Proceedings of the National Academy of Sciences of the United States of America | 26305940 | Proc Natl Acad Sci U S A | 2015 Sep 8 |
Enzyme-Mediated Modification of Single-Domain Antibodies for Imaging Modalities with Different Characteristics. | Rashidian M, Wang L, Edens JG, Jacobsen JT, Hossain I, Wang Q, Victora GD, Vasdev N, Ploegh H, Liang SH | Angewandte Chemie (International ed. in English) | 26630549 | Angew Chem Int Ed Engl | 2016 Jan 11 |
Phenotypic lentivirus screens to identify functional single domain antibodies. | Schmidt FI, Hanke L, Morin B, Brewer R, Brusic V, Whelan SP, Ploegh HL | Nature microbiology | 27573105 | Nat Microbiol | 2016 Jun 20 |
Engineered red blood cells as carriers for systemic delivery of a wide array of functional probes. | Shi J, Kundrat L, Pishesha N, Bilate A, Theile C, Maruyama T, Dougan SK, Ploegh HL, Lodish HF | Proceedings of the National Academy of Sciences of the United States of America | 24982154 | Proc Natl Acad Sci U S A | 2014 Jul 15 |
Graphene Oxide Nanosheets Modified with Single-Domain Antibodies for Rapid and Efficient Capture of Cells. | Chen GY, Li Z, Theile CS, Bardhan NM, Kumar PV, Duarte JN, Maruyama T, Rashidfarrokh A, Belcher AM, Ploegh HL | Chemistry (Weinheim an der Bergstrasse, Germany) | 26472062 | Chemistry | 2015 Nov 23 |
Fluorophore-Conjugated Holliday Junctions for Generating Super-Bright Antibodies and Antibody Fragments. | Li Z, Theile CS, Chen GY, Bilate AM, Duarte JN, Avalos AM, Fang T, Barberena R, Sato S, Ploegh HL | Angewandte Chemie (International ed. in English) | 26252716 | Angew Chem Int Ed Engl | 2015 Sep 28 |
PD-L1 is an activation-independent marker of brown adipocytes. | Ingram JR, Dougan M, Rashidian M, Knoll M, Keliher EJ, Garrett S, Garforth S, Blomberg OS, Espinosa C, Bhan A, Almo SC, Weissleder R, Lodish H, Dougan SK, Ploegh HL | Nature communications | 28935898 | Nat Commun | 2017 Sep 21 |
Targeted antigen delivery by an anti-class II MHC VHH elicits focused αMUC1(Tn) immunity. | Fang T, Van Elssen CHMJ, Duarte JN, Guzman JS, Chahal JS, Ling J, Ploegh HL | Chemical science | 28970938 | Chem Sci | 2017 Aug 1 |
The use of (18)F-2-fluorodeoxyglucose (FDG) to label antibody fragments for immuno-PET of pancreatic cancer. | Rashidian M, Keliher E, Dougan M, Juras PK, Cavallari M, Wojtkiewicz GR, Jacobsen J, Edens JG, Tas JM, Victora G, Weissleder R, Ploegh H | ACS central science | 26955657 | ACS Cent Sci | 2015 Jun 24 |
Epithelial-to-Mesenchymal Transition Contributes to Immunosuppression in Breast Carcinomas. | Dongre A, Rashidian M, Reinhardt F, Bagnato A, Keckesova Z, Ploegh HL, Weinberg RA | Cancer research | 28428275 | Cancer Res | 2017 Aug 1 |
rAMPing Up Stress Signaling: Protein AMPylation in Metazoans. | Truttmann MC, Ploegh HL | Trends in cell biology | 28433487 | Trends Cell Biol | 2017 Aug |
Vesicular stomatitis virus N protein-specific single-domain antibody fragments inhibit replication. | Hanke L, Schmidt FI, Knockenhauer KE, Morin B, Whelan SP, Schwartz TU, Ploegh HL | EMBO reports | 28396572 | EMBO Rep | 2017 Jun |
Enhanced Cell Capture on Functionalized Graphene Oxide Nanosheets through Oxygen Clustering. | Bardhan NM, Kumar PV, Li Z, Ploegh HL, Grossman JC, Belcher AM, Chen GY | ACS nano | 28085249 | ACS Nano | 2017 Feb 28 |
One-step enzymatic modification of the cell surface redirects cellular cytotoxicity and parasite tropism. | Swee LK, Lourido S, Bell GW, Ingram JR, Ploegh HL | ACS chemical biology | 25360987 | ACS Chem Biol | 2015 Feb 20 |
Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor. | Burg JS, Ingram JR, Venkatakrishnan AJ, Jude KM, Dukkipati A, Feinberg EN, Angelini A, Waghray D, Dror RO, Ploegh HL, Garcia KC | Science (New York, N.Y.) | 25745166 | Science | 2015 Mar 6 |
Rapid and Direct VHH and Target Identification by Staphylococcal Surface Display Libraries. | Cavallari M | International journal of molecular sciences | 28704956 | Int J Mol Sci | 2017 Jul 12 |
Generation of Immunity against Pathogens via Single-Domain Antibody-Antigen Constructs. | Duarte JN, Cragnolini JJ, Swee LK, Bilate AM, Bader J, Ingram JR, Rashidfarrokhi A, Fang T, Schiepers A, Hanke L, Ploegh HL | Journal of immunology (Baltimore, Md. : 1950) | 27821668 | J Immunol | 2016 Dec 15 |
HypE-specific nanobodies as tools to modulate HypE-mediated target AMPylation. | Truttmann MC, Wu Q, Stiegeler S, Duarte JN, Ingram J, Ploegh HL | The Journal of biological chemistry | 25678711 | J Biol Chem | 2015 Apr 3 |
Intracellular expression of camelid single-domain antibodies specific for influenza virus nucleoprotein uncovers distinct features of its nuclear localization. | Ashour J, Schmidt FI, Hanke L, Cragnolini J, Cavallari M, Altenburg A, Brewer R, Ingram J, Shoemaker C, Ploegh HL | Journal of virology | 25540369 | J Virol | 2015 Mar |
Durable antitumor responses to CD47 blockade require adaptive immune stimulation. | Sockolosky JT, Dougan M, Ingram JR, Ho CC, Kauke MJ, Almo SC, Ploegh HL, Garcia KC | Proceedings of the National Academy of Sciences of the United States of America | 27091975 | Proc Natl Acad Sci U S A | 2016 May 10 |
Posttranscriptional Regulation of Glycoprotein Quality Control in the Endoplasmic Reticulum Is Controlled by the E2 Ub-Conjugating Enzyme UBC6e. | Hagiwara M, Ling J, Koenig PA, Ploegh HL | Molecular cell | 27570074 | Mol Cell | 2016 Sep 1 |
A census of human soluble protein complexes. | Havugimana PC, Hart GT, Nepusz T, Yang H, Turinsky AL, Li Z, Wang PI, Boutz DR, Fong V, Phanse S, Babu M, Craig SA, Hu P, Wan C, Vlasblom J, Dar VU, Bezginov A, Clark GW, Wu GC, Wodak SJ, Tillier ER, Paccanaro A, Marcotte EM, Emili A | Cell | 22939629 | Cell | 2012 Aug 31 |
Insights into the regulation of protein abundance from proteomic and transcriptomic analyses. | Vogel C, Marcotte EM | Nature reviews. Genetics | 22411467 | Nat Rev Genet | 2012 Mar 13 |
Intrinsic Antimicrobial Resistance Determinants in the Superbug Pseudomonas aeruginosa. | Murray JL, Kwon T, Marcotte EM, Whiteley M | mBio | 26507235 | mBio | 2015 Oct 27 |
Solution-phase and solid-phase sequential, selective modification of side chains in KDYWEC and KDYWE as models for usage in single-molecule protein sequencing. | Hernandez ET, Swaminathan J, Marcotte EM, Anslyn EV | New journal of chemistry = Nouveau journal de chimie | 28983186 | New J Chem | 2017 Jan 21 |
Identifying direct contacts between protein complex subunits from their conditional dependence in proteomics datasets. | Drew K, Müller CL, Bonneau R, Marcotte EM | PLoS computational biology | 29023445 | PLoS Comput Biol | 2017 Oct |
The Many Nuanced Evolutionary Consequences of Duplicated Genes. | Teufel AI, Johnson MM, Laurent JM, Kachroo AH, Marcotte EM, Wilke CO | Molecular biology and evolution | 30428072 | Mol Biol Evol | 2019 Feb 1 |
Photography Coupled with Self-Propagating Chemical Cascades: Differentiation and Quantitation of G- and V-Nerve Agent Mimics via Chromaticity. | Sun X, Boulgakov AA, Smith LN, Metola P, Marcotte EM, Anslyn EV | ACS central science | 30062113 | ACS Cent Sci | 2018 Jul 25 |
Systematic Discovery of Endogenous Human Ribonucleoprotein Complexes. | Mallam AL, Sae-Lee W, Schaub JM, Tu F, Battenhouse A, Jang YJ, Kim J, Wallingford JB, Finkelstein IJ, Marcotte EM, Drew K | Cell reports | 31665645 | Cell Rep | 2019 Oct 29 |
Bringing Microscopy-By-Sequencing into View. | Boulgakov AA, Ellington AD, Marcotte EM | Trends in biotechnology | 31416630 | Trends Biotechnol | 2020 Feb |
Proteomic identification of monoclonal antibodies from serum. | Boutz DR, Horton AP, Wine Y, Lavinder JJ, Georgiou G, Marcotte EM | Analytical chemistry | 24684310 | Anal Chem | 2014 May 20 |
Lanthanide nano-drums: a new class of molecular nanoparticles for potential biomedical applications. | Jones RA, Gnanam AJ, Arambula JF, Jones JN, Swaminathan J, Yang X, Schipper D, Hall JW, DePue LJ, Dieye Y, Vadivelu J, Chandler DJ, Marcotte EM, Sessler JL, Ehrlich LI, Brown KA | Faraday discussions | 25284181 | Faraday Discuss | 2014 |
Paternal chromosome loss and metabolic crisis contribute to hybrid inviability in Xenopus. | Gibeaux R, Acker R, Kitaoka M, Georgiou G, van Kruijsbergen I, Ford B, Marcotte EM, Nomura DK, Kwon T, Veenstra GJC, Heald R | Nature | 29320479 | Nature | 2018 Jan 18 |
Integration of over 9,000 mass spectrometry experiments builds a global map of human protein complexes. | Drew K, Lee C, Huizar RL, Tu F, Borgeson B, McWhite CD, Ma Y, Wallingford JB, Marcotte EM | Molecular systems biology | 28596423 | Mol Syst Biol | 2017 Jun 8 |
The DEAH-box helicase Dhr1 dissociates U3 from the pre-rRNA to promote formation of the central pseudoknot. | Sardana R, Liu X, Granneman S, Zhu J, Gill M, Papoulas O, Marcotte EM, Tollervey D, Correll CC, Johnson AW | PLoS biology | 25710520 | PLoS Biol | 2015 Feb |
Long-term neural and physiological phenotyping of a single human. | Poldrack RA, Laumann TO, Koyejo O, Gregory B, Hover A, Chen MY, Gorgolewski KJ, Luci J, Joo SJ, Boyd RL, Hunicke-Smith S, Simpson ZB, Caven T, Sochat V, Shine JM, Gordon E, Snyder AZ, Adeyemo B, Petersen SE, Glahn DC, Reese Mckay D, Curran JE, Göring HH, Carless MA, Blangero J, Dougherty R, Leemans A, Handwerker DA, Frick L, Marcotte EM, Mumford JA | Nature communications | 26648521 | Nat Commun | 2015 Dec 9 |
Panorama of ancient metazoan macromolecular complexes. | Wan C, Borgeson B, Phanse S, Tu F, Drew K, Clark G, Xiong X, Kagan O, Kwan J, Bezginov A, Chessman K, Pal S, Cromar G, Papoulas O, Ni Z, Boutz DR, Stoilova S, Havugimana PC, Guo X, Malty RH, Sarov M, Greenblatt J, Babu M, Derry WB, Tillier ER, Wallingford JB, Parkinson J, Marcotte EM, Emili A | Nature | 26344197 | Nature | 2015 Sep 17 |
Efforts to make and apply humanized yeast. | Laurent JM, Young JH, Kachroo AH, Marcotte EM | Briefings in functional genomics | 26462863 | Brief Funct Genomics | 2016 Mar |
Evolution. Systematic humanization of yeast genes reveals conserved functions and genetic modularity. | Kachroo AH, Laurent JM, Yellman CM, Meyer AG, Wilke CO, Marcotte EM | Science (New York, N.Y.) | 25999509 | Science | 2015 May 22 |
UVnovo: A de Novo Sequencing Algorithm Using Single Series of Fragment Ions via Chromophore Tagging and 351 nm Ultraviolet Photodissociation Mass Spectrometry. | Robotham SA, Horton AP, Cannon JR, Cotham VC, Marcotte EM, Brodbelt JS | Analytical chemistry | 26938041 | Anal Chem | 2016 Apr 5 |
Systematic bacterialization of yeast genes identifies a near-universally swappable pathway. | Kachroo AH, Laurent JM, Akhmetov A, Szilagyi-Jones M, McWhite CD, Zhao A, Marcotte EM | eLife | 28661399 | Elife | 2017 Jun 29 |
A liquid-like organelle at the root of motile ciliopathy. | Huizar RL, Lee C, Boulgakov AA, Horani A, Tu F, Marcotte EM, Brody SL, Wallingford JB | eLife | 30561330 | Elife | 2018 Dec 18 |
The proteomic response to mutants of the Escherichia coli RNA degradosome. | Zhou L, Zhang AB, Wang R, Marcotte EM, Vogel C | Molecular bioSystems | 23403814 | Mol Biosyst | 2013 Apr 5 |
Statistical approach to protein quantification. | Gerster S, Kwon T, Ludwig C, Matondo M, Vogel C, Marcotte EM, Aebersold R, Bühlmann P | Molecular & cellular proteomics : MCP | 24255132 | Mol Cell Proteomics | 2014 Feb |
Applications of comparative evolution to human disease genetics. | McWhite CD, Liebeskind BJ, Marcotte EM | Current opinion in genetics & development | 26338499 | Curr Opin Genet Dev | 2015 Dec |
Sperm is epigenetically programmed to regulate gene transcription in embryos. | Teperek M, Simeone A, Gaggioli V, Miyamoto K, Allen GE, Erkek S, Kwon T, Marcotte EM, Zegerman P, Bradshaw CR, Peters AH, Gurdon JB, Jullien J | Genome research | 27034506 | Genome Res | 2016 Aug |
Computational discovery of pathway-level genetic vulnerabilities in non-small-cell lung cancer. | Young JH, Peyton M, Seok Kim H, McMillan E, Minna JD, White MA, Marcotte EM | Bioinformatics (Oxford, England) | 26755624 | Bioinformatics | 2016 May 1 |
A highly parallel strategy for storage of digital information in living cells. | Akhmetov A, Ellington AD, Marcotte EM | BMC biotechnology | 30333005 | BMC Biotechnol | 2018 Oct 17 |
Highly parallel single-molecule identification of proteins in zeptomole-scale mixtures. | Swaminathan J, Boulgakov AA, Hernandez ET, Bardo AM, Bachman JL, Marotta J, Johnson AM, Anslyn EV, Marcotte EM | Nature biotechnology | 30346938 | Nat Biotechnol | 2018 Oct 22 |
Protein localization screening in vivo reveals novel regulators of multiciliated cell development and function. | Tu F, Sedzinski J, Ma Y, Marcotte EM, Wallingford JB | Journal of cell science | 29180514 | J Cell Sci | 2018 Jan 29 |
Modes of interaction between individuals dominate the topologies of real world networks. | Lee I, Kim E, Marcotte EM | PloS one | 25793969 | PLoS One | 2015 |
Controlled Measurement and Comparative Analysis of Cellular Components in E. coli Reveals Broad Regulatory Changes in Response to Glucose Starvation. | Houser JR, Barnhart C, Boutz DR, Carroll SM, Dasgupta A, Michener JK, Needham BD, Papoulas O, Sridhara V, Sydykova DK, Marx CJ, Trent MS, Barrick JE, Marcotte EM, Wilke CO | PLoS computational biology | 26275208 | PLoS Comput Biol | 2015 Aug |
Protein-to-mRNA ratios are conserved between Pseudomonas aeruginosa strains. | Kwon T, Huse HK, Vogel C, Whiteley M, Marcotte EM | Journal of proteome research | 24742327 | J Proteome Res | 2014 May 2 |
Synthesis of Carboxy ATTO 647N Using Redox Cycling for Xanthone Access. | Bachman JL, Pavlich CI, Boley AJ, Marcotte EM, Anslyn EV | Organic letters | 31825225 | Org Lett | 2020 Jan 17 |
Systematic comparison of variant calling pipelines using gold standard personal exome variants. | Hwang S, Kim E, Lee I, Marcotte EM | Scientific reports | 26639839 | Sci Rep | 2015 Dec 7 |
A self-assembling lanthanide molecular nanoparticle for optical imaging. | Brown KA, Yang X, Schipper D, Hall JW, DePue LJ, Gnanam AJ, Arambula JF, Jones JN, Swaminathan J, Dieye Y, Vadivelu J, Chandler DJ, Marcotte EM, Sessler JL, Ehrlich LI, Jones RA | Dalton transactions (Cambridge, England : 2003) | 25512085 | Dalton Trans | 2015 Feb 14 |
An efficient methodology to introduce o-(aminomethyl)phenyl-boronic acids into peptides: alkylation of secondary amines. | Hernandez ET, Kolesnichenko IV, Reuther JF, Anslyn EV | New journal of chemistry = Nouveau journal de chimie | 28649175 | New J Chem | 2017 Jan 7 |
Metabolic crosstalk regulates Porphyromonas gingivalis colonization and virulence during oral polymicrobial infection. | Kuboniwa M, Houser JR, Hendrickson EL, Wang Q, Alghamdi SA, Sakanaka A, Miller DP, Hutcherson JA, Wang T, Beck DAC, Whiteley M, Amano A, Wang H, Marcotte EM, Hackett M, Lamont RJ | Nature microbiology | 28924191 | Nat Microbiol | 2017 Nov |
Improved Xanthone Synthesis, Stepwise Chemical Redox Cycling. | Bachman JL, Escamilla PR, Boley AJ, Pavlich CI, Anslyn EV | Organic letters | 30582707 | Org Lett | 2019 Jan 4 |
HumanNet v2: human gene networks for disease research. | Hwang S, Kim CY, Yang S, Kim E, Hart T, Marcotte EM, Lee I | Nucleic acids research | 30418591 | Nucleic Acids Res | 2019 Jan 8 |
Classification of Single Particles from Human Cell Extract Reveals Distinct Structures. | Verbeke EJ, Mallam AL, Drew K, Marcotte EM, Taylor DW | Cell reports | 29972786 | Cell Rep | 2018 Jul 3 |
2,2'-Bipyridine and hydrazide containing peptides for cyclization and complex quaternary structural control. | Hernandez ET, Rogelio Escamilla P, Kwon SY, Partridge J, McVeigh M, Rivera S, Reuther JF, Anslyn EV | New journal of chemistry = Nouveau journal de chimie | 30386131 | New J Chem | 2018 Jun 7 |
Single-step Precision Genome Editing in Yeast Using CRISPR-Cas9. | Akhmetov A, Laurent JM, Gollihar J, Gardner EC, Garge RK, Ellington AD, Kachroo AH, Marcotte EM | Bio-protocol | 29770349 | Bio Protoc | 2018 Mar 20 |
The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery. | Toriyama M, Lee C, Taylor SP, Duran I, Cohn DH, Bruel AL, Tabler JM, Drew K, Kelly MR, Kim S, Park TJ, Braun DA, Pierquin G, Biver A, Wagner K, Malfroot A, Panigrahi I, Franco B, Al-Lami HA, Yeung Y, Choi YJ, University of Washington Center for Mendelian Genomics, Duffourd Y, Faivre L, Rivière JB, Chen J, Liu KJ, Marcotte EM, Hildebrandt F, Thauvin-Robinet C, Krakow D, Jackson PK, Wallingford JB | Nature genetics | 27158779 | Nat Genet | 2016 Jun |
Systems-wide Studies Uncover Commander, a Multiprotein Complex Essential to Human Development. | Mallam AL, Marcotte EM | Cell systems | 28544880 | Cell Syst | 2017 May 24 |
A proteomic survey of widespread protein aggregation in yeast. | O'Connell JD, Tsechansky M, Royal A, Boutz DR, Ellington AD, Marcotte EM | Molecular bioSystems | 24488121 | Mol Biosyst | 2014 Apr |
Bacteriophages use an expanded genetic code on evolutionary paths to higher fitness. | Hammerling MJ, Ellefson JW, Boutz DR, Marcotte EM, Ellington AD, Barrick JE | Nature chemical biology | 24487692 | Nat Chem Biol | 2014 Mar |
MouseNet v2: a database of gene networks for studying the laboratory mouse and eight other model vertebrates. | Kim E, Hwang S, Kim H, Shim H, Kang B, Yang S, Shim JH, Shin SY, Marcotte EM, Lee I | Nucleic acids research | 26527726 | Nucleic Acids Res | 2016 Jan 4 |
Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes. | Phanse S, Wan C, Borgeson B, Tu F, Drew K, Clark G, Xiong X, Kagan O, Kwan J, Bezginov A, Chessman K, Pal S, Cromar G, Papoulas O, Ni Z, Boutz DR, Stoilova S, Havugimana PC, Guo X, Malty RH, Sarov M, Greenblatt J, Babu M, Derry WB, Tillier ER, Wallingford JB, Parkinson J, Marcotte EM, Emili A | Data in brief | 26870755 | Data Brief | 2016 Mar |
A theoretical justification for single molecule peptide sequencing. | Swaminathan J, Boulgakov AA, Marcotte EM | PLoS computational biology | 25714988 | PLoS Comput Biol | 2015 Feb |
Towards Consensus Gene Ages. | Liebeskind BJ, McWhite CD, Marcotte EM | Genome biology and evolution | 27259914 | Genome Biol Evol | 2016 Jun 27 |
Global tRNA misacylation induced by anaerobiosis and antibiotic exposure broadly increases stress resistance in Escherichia coli. | Schwartz MH, Waldbauer JR, Zhang L, Pan T | Nucleic acids research | 27672035 | Nucleic Acids Res | 2016 Dec 1 |
Methionine Mistranslation Bypasses the Restraint of the Genetic Code to Generate Mutant Proteins with Distinct Activities. | Wang X, Pan T | PLoS genetics | 26709516 | PLoS Genet | 2015 Dec |
Diversity of human tRNA genes from the 1000-genomes project. | Parisien M, Wang X, Pan T | RNA biology | 24448271 | RNA Biol | 2013 Dec |
My adventure in tRNA biology, so far. | Pan T | RNA (New York, N.Y.) | 25780201 | RNA | 2015 Apr |
Efficient and quantitative high-throughput tRNA sequencing. | Zheng G, Qin Y, Clark WC, Dai Q, Yi C, He C, Lambowitz AM, Pan T | Nature methods | 26214130 | Nat Methods | 2015 Sep |
tRNA base methylation identification and quantification via high-throughput sequencing. | Clark WC, Evans ME, Dominissini D, Zheng G, Pan T | RNA (New York, N.Y.) | 27613580 | RNA | 2016 Nov |
tRNA Misacylation with Methionine in the Mouse Gut Microbiome in Situ. | Schwartz MH, Pan T | Microbial ecology | 28070678 | Microb Ecol | 2017 Jul |
Codon optimality controls differential mRNA translation during amino acid starvation. | Saikia M, Wang X, Mao Y, Wan J, Pan T, Qian SB | RNA (New York, N.Y.) | 27613579 | RNA | 2016 Nov |
Evolutionary Gain of Alanine Mischarging to Noncognate tRNAs with a G4:U69 Base Pair. | Sun L, Gomes AC, He W, Zhou H, Wang X, Pan DW, Schimmel P, Pan T, Yang XL | Journal of the American Chemical Society | 27622773 | J Am Chem Soc | 2016 Oct 5 |
Temperature dependent mistranslation in a hyperthermophile adapts proteins to lower temperatures. | Schwartz MH, Pan T | Nucleic acids research | 26657639 | Nucleic Acids Res | 2016 Jan 8 |
Adaptive translation as a mechanism of stress response and adaptation. | Pan T | Annual review of genetics | 23988117 | Annu Rev Genet | 2013 |
N(6)-Methyladenosine Modification in a Long Noncoding RNA Hairpin Predisposes Its Conformation to Protein Binding. | Zhou KI, Parisien M, Dai Q, Liu N, Diatchenko L, Sachleben JR, Pan T | Journal of molecular biology | 26343757 | J Mol Biol | 2016 Feb 27 |
Interaction of tRNA with MEK2 in pancreatic cancer cells. | Wang X, Chow CR, Ebine K, Lee J, Rosner MR, Pan T, Munshi HG | Scientific reports | 27301426 | Sci Rep | 2016 Jun 15 |
Determining the fidelity of tRNA aminoacylation via microarrays. | Schwartz MH, Pan T | Methods (San Diego, Calif.) | 27639882 | Methods | 2017 Jan 15 |
Modifications and functional genomics of human transfer RNA. | Pan T | Cell research | 29463900 | Cell Res | 2018 Apr |
Misacylation of tRNA with methionine in Saccharomyces cerevisiae. | Wiltrout E, Goodenbour JM, Fréchin M, Pan T | Nucleic acids research | 22941646 | Nucleic Acids Res | 2012 Nov 1 |
Function and origin of mistranslation in distinct cellular contexts. | Schwartz MH, Pan T | Critical reviews in biochemistry and molecular biology | 28075177 | Crit Rev Biochem Mol Biol | 2017 Apr |
A dual fluorescent reporter for the investigation of methionine mistranslation in live cells. | Gomes AC, Kordala AJ, Strack R, Wang X, Geslain R, Delaney K, Clark WC, Keenan R, Pan T | RNA (New York, N.Y.) | 26729921 | RNA | 2016 Mar |
Stress Response and Adaptation Mediated by Amino Acid Misincorporation during Protein Synthesis. | Wang X, Pan T | Advances in nutrition (Bethesda, Md.) | 27422514 | Adv Nutr | 2016 Jul |
Selective Enzymatic Demethylation of N(2) ,N(2) -Dimethylguanosine in RNA and Its Application in High-Throughput tRNA Sequencing. | Dai Q, Zheng G, Schwartz MH, Clark WC, Pan T | Angewandte Chemie (International ed. in English) | 28371071 | Angew Chem Int Ed Engl | 2017 Apr 24 |
Improving membrane protein expression by optimizing integration efficiency. | Niesen MJM, Marshall SS, Miller TF 3rd, Clemons WM Jr | The Journal of biological chemistry | 28918393 | J Biol Chem | 2017 Nov 24 |
Chemoenzymatic syntheses of water-soluble lipid I fluorescent probes. | Mitachi K, Siricilla S, Klaic L, Clemons WM Jr, Kurosu M | Tetrahedron letters | 26190869 | Tetrahedron Lett | 2015 Jun 3 |
Structurally derived universal mechanism for the catalytic cycle of the tail-anchored targeting factor Get3. | Fry MY, Najdrová V, Maggiolo AO, Saladi SM, Doležal P, Clemons WM Jr | Nature structural & molecular biology | 35851188 | Nat Struct Mol Biol | 2022 Aug |
A Link between Integral Membrane Protein Expression and Simulated Integration Efficiency. | Marshall SS, Niesen MJM, Müller A, Tiemann K, Saladi SM, Galimidi RP, Zhang B, Clemons WM Jr, Miller TF 3rd | Cell reports | 27524616 | Cell Rep | 2016 Aug 23 |
Comprehensive proteomic profiling of outer membrane vesicles from Campylobacter jejuni. | Jang KS, Sweredoski MJ, Graham RL, Hess S, Clemons WM Jr | Journal of proteomics | 24382552 | J Proteomics | 2014 Feb 26 |
A statistical model for improved membrane protein expression using sequence-derived features. | Saladi SM, Javed N, Müller A, Clemons WM Jr | The Journal of biological chemistry | 29378850 | J Biol Chem | 2018 Mar 30 |
A cationic cysteine-hydrazide as an enrichment tool for the mass spectrometric characterization of bacterial free oligosaccharides. | Jang KS, Nani RR, Kalli A, Levin S, Müller A, Hess S, Reisman SE, Clemons WM Jr | Analytical and bioanalytical chemistry | 26100547 | Anal Bioanal Chem | 2015 Aug |
Sequence-based features that are determinant for tail-anchored membrane protein sorting in eukaryotes. | Fry MY, Saladi SM, Cunha A, Clemons WM Jr | Traffic (Copenhagen, Denmark) | 34288289 | Traffic | 2021 Sep |
Molecular basis of tail-anchored integral membrane protein recognition by the cochaperone Sgt2. | Lin KF, Fry MY, Saladi SM, Clemons WM Jr | The Journal of biological chemistry | 33610544 | J Biol Chem | 2021 Jan-Jun |
The STI1-domain is a flexible alpha-helical fold with a hydrophobic groove. | Fry MY, Saladi SM, Clemons WM Jr | Protein science : a publication of the Protein Society | 33620121 | Protein Sci | 2021 Apr |
Structures of Get3d reveal a distinct architecture associated with the emergence of photosynthesis. | Barlow AN, Manu MS, Saladi SM, Tarr PT, Yadav Y, Thinn AMM, Zhu Y, Laganowsky AD, Clemons WM Jr, Ramasamy S | The Journal of biological chemistry | 37100288 | J Biol Chem | 2023 Jun |
The checkpoint for agonist selection precedes conventional selection in human thymus. | Verstichel G, Vermijlen D, Martens L, Goetgeluk G, Brouwer M, Thiault N, Van Caeneghem Y, De Munter S, Weening K, Bonte S, Leclercq G, Taghon T, Kerre T, Saeys Y, Van Dorpe J, Cheroutre H, Vandekerckhove B | Science immunology | 28783686 | Sci Immunol | 2017 Feb 24 |
Following the fate of one insulin-reactive CD4 T cell: conversion into Teffs and Tregs in the periphery controls diabetes in NOD mice. | Fousteri G, Jasinski J, Dave A, Nakayama M, Pagni P, Lambolez F, Juntti T, Sarikonda G, Cheng Y, Croft M, Cheroutre H, Eisenbarth G, von Herrath M | Diabetes | 22403296 | Diabetes | 2012 May |
Negative selection of self-reactive chicken B cells requires B cell receptor signaling and is independent of the bursal microenvironment. | Davani D, Pancer Z, Cheroutre H, Ratcliffe MJ | Journal of immunology (Baltimore, Md. : 1950) | 24516196 | J Immunol | 2014 Apr 1 |
Controlling airborne cues to study small animal navigation. | Gershow M, Berck M, Mathew D, Luo L, Kane EA, Carlson JR, Samuel AD | Nature methods | 22245808 | Nat Methods | 2012 Jan 15 |
Imaging whole nervous systems: insights into behavior from worms to fish. | Calarco JA, Samuel ADT | Nature methods | 30573822 | Nat Methods | 2019 Jan |
Functional diversity among sensory receptors in a Drosophila olfactory circuit. | Mathew D, Martelli C, Kelley-Swift E, Brusalis C, Gershow M, Samuel AD, Emonet T, Carlson JR | Proceedings of the National Academy of Sciences of the United States of America | 23690583 | Proc Natl Acad Sci U S A | 2013 Jun 4 |
Pan-neuronal imaging in roaming Caenorhabditis elegans. | Venkatachalam V, Ji N, Wang X, Clark C, Mitchell JK, Klein M, Tabone CJ, Florman J, Ji H, Greenwood J, Chisholm AD, Srinivasan J, Alkema M, Zhen M, Samuel AD | Proceedings of the National Academy of Sciences of the United States of America | 26711989 | Proc Natl Acad Sci U S A | 2016 Feb 23 |
The Ionotropic Receptors IR21a and IR25a mediate cool sensing in Drosophila. | Ni L, Klein M, Svec KV, Budelli G, Chang EC, Ferrer AJ, Benton R, Samuel AD, Garrity PA | eLife | 27126188 | Elife | 2016 Apr 29 |
An extrasynaptic GABAergic signal modulates a pattern of forward movement in Caenorhabditis elegans. | Shen Y, Wen Q, Liu H, Zhong C, Qin Y, Harris G, Kawano T, Wu M, Xu T, Samuel AD, Zhang Y | eLife | 27138642 | Elife | 2016 May 3 |
Integration of Plasticity Mechanisms within a Single Sensory Neuron of C. elegans Actuates a Memory. | Hawk JD, Calvo AC, Liu P, Almoril-Porras A, Aljobeh A, Torruella-Suárez ML, Ren I, Cook N, Greenwood J, Luo L, Wang ZW, Samuel ADT, Colón-Ramos DA | Neuron | 29307713 | Neuron | 2018 Jan 17 |
Reverse-correlation analysis of navigation dynamics in Drosophila larva using optogenetics. | Hernandez-Nunez L, Belina J, Klein M, Si G, Claus L, Carlson JR, Samuel AD | eLife | 25942453 | Elife | 2015 May 5 |
Contrasting responses within a single neuron class enable sex-specific attraction in Caenorhabditis elegans. | Narayan A, Venkatachalam V, Durak O, Reilly DK, Bose N, Schroeder FC, Samuel AD, Srinivasan J, Sternberg PW | Proceedings of the National Academy of Sciences of the United States of America | 26903633 | Proc Natl Acad Sci U S A | 2016 Mar 8 |
Structured Odorant Response Patterns across a Complete Olfactory Receptor Neuron Population. | Si G, Kanwal JK, Hu Y, Tabone CJ, Baron J, Berck M, Vignoud G, Samuel ADT | Neuron | 30683545 | Neuron | 2019 Mar 6 |
The wiring diagram of a glomerular olfactory system. | Berck ME, Khandelwal A, Claus L, Hernandez-Nunez L, Si G, Tabone CJ, Li F, Truman JW, Fetter RD, Louis M, Samuel AD, Cardona A | eLife | 27177418 | Elife | 2016 May 13 |
Two alternating motor programs drive navigation in Drosophila larva. | Lahiri S, Shen K, Klein M, Tang A, Kane E, Gershow M, Garrity P, Samuel AD | PloS one | 21858019 | PLoS One | 2011 |
Sensorimotor structure of Drosophila larva phototaxis. | Kane EA, Gershow M, Afonso B, Larderet I, Klein M, Carter AR, de Bivort BL, Sprecher SG, Samuel AD | Proceedings of the National Academy of Sciences of the United States of America | 24043822 | Proc Natl Acad Sci U S A | 2013 Oct 1 |
Distinct combinations of variant ionotropic glutamate receptors mediate thermosensation and hygrosensation in Drosophila. | Knecht ZA, Silbering AF, Ni L, Klein M, Budelli G, Bell R, Abuin L, Ferrer AJ, Samuel AD, Benton R, Garrity PA | eLife | 27656904 | Elife | 2016 Sep 22 |
The power and promise of applying genomics to honey bee health. | Grozinger CM, Robinson GE | Current opinion in insect science | 26273565 | Curr Opin Insect Sci | 2015 Aug 1 |
Three-dimensional mapping and regulation of action potential propagation in nanoelectronics-innervated tissues. | Dai X, Zhou W, Gao T, Liu J, Lieber CM | Nature nanotechnology | 27347837 | Nat Nanotechnol | 2016 Sep |
Flexible electrical recording from cells using nanowire transistor arrays. | Cohen-Karni T, Timko BP, Weiss LE, Lieber CM | Proceedings of the National Academy of Sciences of the United States of America | 19365078 | Proc Natl Acad Sci U S A | 2009 May 5 |
Nano-Bioelectronics. | Zhang A, Lieber CM | Chemical reviews | 26691648 | Chem Rev | 2016 Jan 13 |
General strategy for biodetection in high ionic strength solutions using transistor-based nanoelectronic sensors. | Gao N, Zhou W, Jiang X, Hong G, Fu TM, Lieber CM | Nano letters | 25664395 | Nano Lett | 2015 Mar 11 |
Syringe-injectable electronics. | Liu J, Fu TM, Cheng Z, Hong G, Zhou T, Jin L, Duvvuri M, Jiang Z, Kruskal P, Xie C, Suo Z, Fang Y, Lieber CM | Nature nanotechnology | 26053995 | Nat Nanotechnol | 2015 Jul |
Multifunctional three-dimensional macroporous nanoelectronic networks for smart materials. | Liu J, Xie C, Dai X, Jin L, Zhou W, Lieber CM | Proceedings of the National Academy of Sciences of the United States of America | 23569270 | Proc Natl Acad Sci U S A | 2013 Apr 23 |
Long term stability of nanowire nanoelectronics in physiological environments. | Zhou W, Dai X, Fu TM, Xie C, Liu J, Lieber CM | Nano letters | 24479700 | Nano Lett | 2014 Mar 12 |
Zinc-finger nucleases for somatic gene therapy: the next frontier. | Rahman SH, Maeder ML, Joung JK, Cathomen T | Human gene therapy | 21631241 | Hum Gene Ther | 2011 Aug |
Interactome maps of mouse gene regulatory domains reveal basic principles of transcriptional regulation. | Kieffer-Kwon KR, Tang Z, Mathe E, Qian J, Sung MH, Li G, Resch W, Baek S, Pruett N, Grøntved L, Vian L, Nelson S, Zare H, Hakim O, Reyon D, Yamane A, Nakahashi H, Kovalchuk AL, Zou J, Joung JK, Sartorelli V, Wei CL, Ruan X, Hager GL, Ruan Y, Casellas R | Cell | 24360274 | Cell | 2013 Dec 19 |
Isocitrate Dehydrogenase Mutations Confer Dasatinib Hypersensitivity and SRC Dependence in Intrahepatic Cholangiocarcinoma. | Saha SK, Gordan JD, Kleinstiver BP, Vu P, Najem MS, Yeo JC, Shi L, Kato Y, Levin RS, Webber JT, Damon LJ, Egan RK, Greninger P, McDermott U, Garnett MJ, Jenkins RL, Rieger-Christ KM, Sullivan TB, Hezel AF, Liss AS, Mizukami Y, Goyal L, Ferrone CR, Zhu AX, Joung JK, Shokat KM, Benes CH, Bardeesy N | Cancer discovery | 27231123 | Cancer Discov | 2016 Jul |
CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR-Cas9 nuclease off-targets. | Tsai SQ, Nguyen NT, Malagon-Lopez J, Topkar VV, Aryee MJ, Joung JK | Nature methods | 28459458 | Nat Methods | 2017 Jun |
Efficient genome editing in zebrafish using a CRISPR-Cas system. | Hwang WY, Fu Y, Reyon D, Maeder ML, Tsai SQ, Sander JD, Peterson RT, Yeh JR, Joung JK | Nature biotechnology | 23360964 | Nat Biotechnol | 2013 Mar |
CRISPR-Cas systems for editing, regulating and targeting genomes. | Sander JD, Joung JK | Nature biotechnology | 24584096 | Nat Biotechnol | 2014 Apr |
Locus-specific editing of histone modifications at endogenous enhancers. | Mendenhall EM, Williamson KE, Reyon D, Zou JY, Ram O, Joung JK, Bernstein BE | Nature biotechnology | 24013198 | Nat Biotechnol | 2013 Dec |
Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells. | Liao J, Karnik R, Gu H, Ziller MJ, Clement K, Tsankov AM, Akopian V, Gifford CA, Donaghey J, Galonska C, Pop R, Reyon D, Tsai SQ, Mallard W, Joung JK, Rinn JL, Gnirke A, Meissner A | Nature genetics | 25822089 | Nat Genet | 2015 May |
Context influences on TALE-DNA binding revealed by quantitative profiling. | Rogers JM, Barrera LA, Reyon D, Sander JD, Kellis M, Joung JK, Bulyk ML | Nature communications | 26067805 | Nat Commun | 2015 Jun 11 |
Hypoxia drives transient site-specific copy gain and drug-resistant gene expression. | Black JC, Atabakhsh E, Kim J, Biette KM, Van Rechem C, Ladd B, Burrowes PD, Donado C, Mattoo H, Kleinstiver BP, Song B, Andriani G, Joung JK, Iliopoulos O, Montagna C, Pillai S, Getz G, Whetstine JR | Genes & development | 25995187 | Genes Dev | 2015 May 15 |
A zebrafish model of myelodysplastic syndrome produced through tet2 genomic editing. | Gjini E, Mansour MR, Sander JD, Moritz N, Nguyen AT, Kesarsing M, Gans E, He S, Chen S, Ko M, Kuang YY, Yang S, Zhou Y, Rodig S, Zon LI, Joung JK, Rao A, Look AT | Molecular and cellular biology | 25512612 | Mol Cell Biol | 2015 Mar |
CRISPR RNA-guided activation of endogenous human genes. | Maeder ML, Linder SJ, Cascio VM, Fu Y, Ho QH, Joung JK | Nature methods | 23892898 | Nat Methods | 2013 Oct |
Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage. | Hill SJ, Rolland T, Adelmant G, Xia X, Owen MS, Dricot A, Zack TI, Sahni N, Jacob Y, Hao T, McKinney KM, Clark AP, Reyon D, Tsai SQ, Joung JK, Beroukhim R, Marto JA, Vidal M, Gaudet S, Hill DE, Livingston DM | Genes & development | 25184681 | Genes Dev | 2014 Sep 1 |
Genome Editing in Human Cells Using CRISPR/Cas Nucleases. | Wyvekens N, Tsai SQ, Joung JK | Current protocols in molecular biology | 26423589 | Curr Protoc Mol Biol | 2015 Oct 1 |
IκB kinase β (IKBKB) mutations in lymphomas that constitutively activate canonical nuclear factor κB (NFκB) signaling. | Kai X, Chellappa V, Donado C, Reyon D, Sekigami Y, Ataca D, Louissaint A, Mattoo H, Joung JK, Pillai S | The Journal of biological chemistry | 25107905 | J Biol Chem | 2014 Sep 26 |
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells. | Fu Y, Foden JA, Khayter C, Maeder ML, Reyon D, Joung JK, Sander JD | Nature biotechnology | 23792628 | Nat Biotechnol | 2013 Sep |
TALENs: a widely applicable technology for targeted genome editing. | Joung JK, Sander JD | Nature reviews. Molecular cell biology | 23169466 | Nat Rev Mol Cell Biol | 2013 Jan |
Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition. | Kleinstiver BP, Prew MS, Tsai SQ, Nguyen NT, Topkar VV, Zheng Z, Joung JK | Nature biotechnology | 26524662 | Nat Biotechnol | 2015 Dec |
Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells. | Kleinstiver BP, Tsai SQ, Prew MS, Nguyen NT, Welch MM, Lopez JM, McCaw ZR, Aryee MJ, Joung JK | Nature biotechnology | 27347757 | Nat Biotechnol | 2016 Aug |
High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects. | Kleinstiver BP, Pattanayak V, Prew MS, Tsai SQ, Nguyen NT, Zheng Z, Joung JK | Nature | 26735016 | Nature | 2016 Jan 28 |
Defining and improving the genome-wide specificities of CRISPR-Cas9 nucleases. | Tsai SQ, Joung JK | Nature reviews. Genetics | 27087594 | Nat Rev Genet | 2016 May |
Nodal patterning without Lefty inhibitory feedback is functional but fragile. | Rogers KW, Lord ND, Gagnon JA, Pauli A, Zimmerman S, Aksel DC, Reyon D, Tsai SQ, Joung JK, Schier AF | eLife | 29215332 | Elife | 2017 Dec 7 |
Functional analysis of Collagen 17a1: A genetic modifier of junctional epidermolysis bullosa in mice. | Sproule TJ, Wilpan RY, Low BE, Silva KA, Reyon D, Joung JK, Wiles MV, Roopenian DC, Sundberg JP | PloS one | 37796769 | PLoS One | 2023 |
Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins. | Maeder ML, Angstman JF, Richardson ME, Linder SJ, Cascio VM, Tsai SQ, Ho QH, Sander JD, Reyon D, Bernstein BE, Costello JF, Wilkinson MF, Joung JK | Nature biotechnology | 24108092 | Nat Biotechnol | 2013 Dec |
Defining genome-wide CRISPR-Cas genome-editing nuclease activity with GUIDE-seq. | Malinin NL, Lee G, Lazzarotto CR, Li Y, Zheng Z, Nguyen NT, Liebers M, Topkar VV, Iafrate AJ, Le LP, Aryee MJ, Joung JK, Tsai SQ | Nature protocols | 34773119 | Nat Protoc | 2021 Dec |
Improving CRISPR-Cas nuclease specificity using truncated guide RNAs. | Fu Y, Sander JD, Reyon D, Cascio VM, Joung JK | Nature biotechnology | 24463574 | Nat Biotechnol | 2014 Mar |
Defining CRISPR-Cas9 genome-wide nuclease activities with CIRCLE-seq. | Lazzarotto CR, Nguyen NT, Tang X, Malagon-Lopez J, Guo JA, Aryee MJ, Joung JK, Tsai SQ | Nature protocols | 30341435 | Nat Protoc | 2018 Nov |
Efficient CRISPR/Cas9-mediated editing of trinucleotide repeat expansion in myotonic dystrophy patient-derived iPS and myogenic cells. | Dastidar S, Ardui S, Singh K, Majumdar D, Nair N, Fu Y, Reyon D, Samara E, Gerli MFM, Klein AF, De Schrijver W, Tipanee J, Seneca S, Tulalamba W, Wang H, Chai YC, In't Veld P, Furling D, Tedesco FS, Vermeesch JR, Joung JK, Chuah MK, VandenDriessche T | Nucleic acids research | 29947794 | Nucleic Acids Res | 2018 Sep 19 |
piggyBac transposase tools for genome engineering. | Li X, Burnight ER, Cooney AL, Malani N, Brady T, Sander JD, Staber J, Wheelan SJ, Joung JK, McCray PB Jr, Bushman FD, Sinn PL, Craig NL | Proceedings of the National Academy of Sciences of the United States of America | 23723351 | Proc Natl Acad Sci U S A | 2013 Jun 18 |
In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites. | Sander JD, Ramirez CL, Linder SJ, Pattanayak V, Shoresh N, Ku M, Foden JA, Reyon D, Bernstein BE, Liu DR, Joung JK | Nucleic acids research | 23945932 | Nucleic Acids Res | 2013 Oct |
Induction of stable drug resistance in human breast cancer cells using a combinatorial zinc finger transcription factor library. | Lee J, Hirsh AS, Wittner BS, Maeder ML, Singavarapu R, Lang M, Janarthanan S, McDermott U, Yajnik V, Ramaswamy S, Joung JK, Sgroi DC | PloS one | 21818254 | PLoS One | 2011 |
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Engineering a genetically-encoded SHG chromophore by electrostatic targeting to the membrane. | Jinno Y, Shoda K, Rial-Verde E, Yuste R, Miyawaki A, Tsutsui H | Frontiers in molecular neuroscience | 25505870 | Front Mol Neurosci | 2014 |
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Non-overlapping Neural Networks in Hydra vulgaris. | Dupre C, Yuste R | Current biology : CB | 28366745 | Curr Biol | 2017 Apr 24 |
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AAV8BP2 and AAV8 transduce the mammalian cochlear lateral wall and endolymphatic sac with high efficiency. | Isgrig K, Ishibashi Y, Lee HJ, Zhu J, Grati M, Bennett J, Griffith AJ, Roux I, Chien WW | Molecular therapy. Methods & clinical development | 36034771 | Mol Ther Methods Clin Dev | 2022 Sep 8 |
Refining surgical techniques for efficient posterior semicircular canal gene delivery in the adult mammalian inner ear with minimal hearing loss. | Zhu J, Choi JW, Ishibashi Y, Isgrig K, Grati M, Bennett J, Chien W | Scientific reports | 34552193 | Sci Rep | 2021 Sep 22 |
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AAV2.7m8 is a powerful viral vector for inner ear gene therapy. | Isgrig K, McDougald DS, Zhu J, Wang HJ, Bennett J, Chien WW | Nature communications | 30683875 | Nat Commun | 2019 Jan 25 |
Novel mobility test to assess functional vision in patients with inherited retinal dystrophies. | Chung DC, McCague S, Yu ZF, Thill S, DiStefano-Pappas J, Bennett J, Cross D, Marshall K, Wellman J, High KA | Clinical & experimental ophthalmology | 28697537 | Clin Exp Ophthalmol | 2018 Apr |
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Evaluation of Dose and Safety of AAV7m8 and AAV8BP2 in the Non-Human Primate Retina. | Ramachandran PS, Lee V, Wei Z, Song JY, Casal G, Cronin T, Willett K, Huckfeldt R, Morgan JI, Aleman TS, Maguire AM, Bennett J | Human gene therapy | 27750461 | Hum Gene Ther | 2017 Feb |
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Plasticity of the human visual system after retinal gene therapy in patients with Leber's congenital amaurosis. | Ashtari M, Zhang H, Cook PA, Cyckowski LL, Shindler KS, Marshall KA, Aravand P, Vossough A, Gee JC, Maguire AM, Baker CI, Bennett J | Science translational medicine | 26180100 | Sci Transl Med | 2015 Jul 15 |
An Autogenously Regulated Expression System for Gene Therapeutic Ocular Applications. | Sochor MA, Vasireddy V, Drivas TG, Wojno A, Doung T, Shpylchak I, Bennicelli J, Chung D, Bennett J, Lewis M | Scientific reports | 26597678 | Sci Rep | 2015 Nov 24 |
Evaluating Efficiencies of Dual AAV Approaches for Retinal Targeting. | Carvalho LS, Turunen HT, Wassmer SJ, Luna-Velez MV, Xiao R, Bennett J, Vandenberghe LH | Frontiers in neuroscience | 28943836 | Front Neurosci | 2017 |
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Evaluating Public Health Interventions: 2. Stepping Up to Routine Public Health Evaluation With the Stepped Wedge Design. | Spiegelman D | American journal of public health | 26885961 | Am J Public Health | 2016 Mar |
Service readiness of health facilities in Bangladesh, Haiti, Kenya, Malawi, Namibia, Nepal, Rwanda, Senegal, Uganda and the United Republic of Tanzania. | Leslie HH, Spiegelman D, Zhou X, Kruk ME | Bulletin of the World Health Organization | 29147054 | Bull World Health Organ | 2017 Nov 1 |
Inverse probability weighted estimation of risk under representative interventions in observational studies. | Young JG, Logan RW, Robins JM, Hernán MA | Journal of the American Statistical Association | 31564760 | J Am Stat Assoc | 2019 |
Interpretation of the Individual Effect Under Treatment Spillover. | Crawford FW, Morozova O, Buchanan AL, Spiegelman D | American journal of epidemiology | 31094425 | Am J Epidemiol | 2019 Aug 1 |
Association of the US President's Emergency Plan for AIDS Relief's Funding With Prevention of Mother-to-Child Transmission of HIV in Kenya. | Barnhart DA, Tsikhutsu I, Kirui D, Sawe F, Muli J, Sugut W, Abboud N, Birx D, Hamm T, Coakley P, Hickey PW, Wolfman V, Lee E, Spiegelman D | JAMA network open | 31517966 | JAMA Netw Open | 2019 Sep 4 |
On the Analysis of Case-Control Studies in Cluster-correlated Data Settings. | Haneuse S, Rivera-Rodriguez C | Epidemiology (Cambridge, Mass.) | 29068840 | Epidemiology | 2018 Jan |
Spiegelman Responds. | Spiegelman D | American journal of public health | 27153027 | Am J Public Health | 2016 Jun |
Assessing the quality of tuberculosis care using routine surveillance data: a process evaluation employing the Zero TB Indicator Framework in Mongolia. | Saranjav A, Parisi C, Zhou X, Dorjnamjil K, Samdan T, Erdenebaatar S, Chuluun A, Dalkh T, Ganbaatar G, Brooks MB, Spiegelman D, Ganmaa D, Davis JL | BMJ open | 35973702 | BMJ Open | 2022 Aug 16 |
Assessing Direct and Spillover Effects of Intervention Packages in Network-Randomized Studies. | Buchanan AL, Hernández-Ramírez RU, Lok JJ, Vermund SH, Friedman SR, Forastiere L, Spiegelman D | medRxiv : the preprint server for health sciences | 38352598 | medRxiv | 2024 Feb 1 |
Overall, Direct, Spillover, and Composite Effects of Components of a Peer-Driven Intervention Package on Injection Risk Behavior Among People Who Inject Drugs in the HPTN 037 Study. | Hernández-Ramírez RU, Spiegelman D, Lok JJ, Forastiere L, Friedman SR, Latkin CA, Vermund SH, Buchanan AL | AIDS and behavior | 37932493 | AIDS Behav | 2024 Jan |
A note on "Design and analysis of stepped wedge cluster randomized trials". | Liao X, Zhou X, Spiegelman D | Contemporary clinical trials | 26394003 | Contemp Clin Trials | 2015 Nov |
Evaluating Public Health Interventions: 1. Examples, Definitions, and a Personal Note. | Spiegelman D | American journal of public health | 26562122 | Am J Public Health | 2016 Jan |
Evaluating Public Health Interventions: 5. Causal Inference in Public Health Research-Do Sex, Race, and Biological Factors Cause Health Outcomes? | Glymour MM, Spiegelman D | American journal of public health | 27854526 | Am J Public Health | 2017 Jan |
Comparison of HPV-16 and HPV-18 Genotyping and Cytological Testing as Triage Testing Within Human Papillomavirus-Based Screening in Mexico. | Torres-Ibarra L, Cuzick J, Lorincz AT, Spiegelman D, Lazcano-Ponce E, Franco EL, Moscicki AB, Mahmud SM, Wheeler CM, Rivera-Paredez B, Hernández-López R, León-Maldonado L, Salmerón J, FRIDA Study Group. | JAMA network open | 31747033 | JAMA Netw Open | 2019 Nov 1 |
Facilitators and barriers to healthy eating in a worksite cafeteria: a qualitative study from Nepal. | Shrestha A, Pyakurel P, Shrestha A, Gautam R, Manandhar N, Rhodes E, Tamrakar D, Karmacharya BM, Malik V, Mattei J, Spiegelman D | Heart Asia | 29225703 | Heart Asia | 2017 |
A maximum likelihood approach to power calculations for stepped wedge designs of binary outcomes. | Zhou X, Liao X, Kunz LM, Normand ST, Wang M, Spiegelman D | Biostatistics (Oxford, England) | 30084949 | Biostatistics | 2020 Jan 1 |
Coaching Intensity, Adherence to Essential Birth Practices, and Health Outcomes in the BetterBirth Trial in Uttar Pradesh, India. | Barnhart DA, Spiegelman D, Zigler CM, Kara N, Delaney MM, Kalita T, Maji P, Hirschhorn LR, Semrau KEA | Global health, science and practice | 32127359 | Glob Health Sci Pract | 2020 Mar 30 |
swdpwr: A SAS macro and an R package for power calculations in stepped wedge cluster randomized trials. | Chen J, Zhou X, Li F, Spiegelman D | Computer methods and programs in biomedicine | 34818620 | Comput Methods Programs Biomed | 2022 Jan |
Partial Identification of the Average Treatment Effect Using Instrumental Variables: Review of Methods for Binary Instruments, Treatments, and Outcomes. | Swanson SA, Hernán MA, Miller M, Robins JM, Richardson TS | Journal of the American Statistical Association | 31537952 | J Am Stat Assoc | 2018 |
The Association of Cooking Fuel Use, Dietary Intake, and Blood Pressure among Rural Women in China. | Bellows AL, Spiegelman D, Du S, Jaacks LM | International journal of environmental research and public health | 32751678 | Int J Environ Res Public Health | 2020 Jul 30 |
Estimating the natural indirect effect and the mediation proportion via the product method. | Cheng C, Spiegelman D, Li F | BMC medical research methodology | 34800985 | BMC Med Res Methodol | 2021 Nov 20 |
Mediation analysis in the presence of continuous exposure measurement error. | Cheng C, Spiegelman D, Li F | Statistics in medicine | 36869626 | Stat Med | 2023 May 20 |
Evaluating Public Health Interventions: 3. The Two-Stage Design for Confounding Bias Reduction-Having Your Cake and Eating It Two. | Spiegelman D, Rivera-Rodriguez CL, Haneuse S | American journal of public health | 27285260 | Am J Public Health | 2016 Jul |
On the analysis of two-phase designs in cluster-correlated data settings. | Rivera-Rodriguez C, Spiegelman D, Haneuse S | Statistics in medicine | 31359448 | Stat Med | 2019 Oct 15 |
Optimizing the development and evaluation of complex interventions: lessons learned from the BetterBirth Program and associated trial. | Barnhart DA, Semrau KEA, Zigler CM, Molina RL, Delaney MM, Hirschhorn LR, Spiegelman D | Implementation science communications | 32885188 | Implement Sci Commun | 2020 |
Worksite intervention study to prevent diabetes in Nepal: a randomised trial protocol. | Pyakurel P, Shrestha A, Karmacharya BM, Budhathoki SS, Chaudhari RK, Tamrakar D, Shrestha A, Karmacharya RM, Shrestha A, Sharma S, Sharma SK, Spiegelman D | Open heart | 32847993 | Open Heart | 2020 Aug |
Survival analysis with functions of mismeasured covariate histories: the case of chronic air pollution exposure in relation to mortality in the nurses' health study. | Liao X, Zhou X, Wang M, Hart JE, Laden F, Spiegelman D | Journal of the Royal Statistical Society. Series C, Applied statistics | 29430064 | J R Stat Soc Ser C Appl Stat | 2018 Feb |
Multiple robust estimation of marginal structural mean models for unconstrained outcomes. | Babino L, Rotnitzky A, Robins J | Biometrics | 30004573 | Biometrics | 2019 Mar |
Access of choice-disabled young women in Botswana to government structural support programmes: a cross-sectional study. | Cockcroft A, Marokoane N, Kgakole L, Tswetla N, Andersson N | AIDS care | 29848044 | AIDS Care | 2018 Jun |
Evaluating Public Health Interventions: 7. Let the Subject Matter Choose the Effect Measure: Ratio, Difference, or Something Else Entirely. | Spiegelman D, Khudyakov P, Wang M, Vanderweele TJ | American journal of public health | 29161073 | Am J Public Health | 2018 Jan |
Exposure misclassification in propensity score-based time-to-event data analysis. | Yang Y, Wang M | Statistical methods in medical research | 33826453 | Stat Methods Med Res | 2021 May |
How are qualitative methods used in implementation science research? A scoping review protocol. | Hagaman A, Rhodes EC, Nyhan K, Katague M, Schwartz A, Spiegelman D | JBI evidence synthesis | 33323772 | JBI Evid Synth | 2021 Jun |
Evaluating Public Health Interventions: 6. Modeling Ratios or Differences? Let the Data Tell Us. | Spiegelman D, VanderWeele TJ | American journal of public health | 28590865 | Am J Public Health | 2017 Jul |
The fidelity of implementation of recommended care for children with malaria by community health workers in Nigeria. | Adeoti O, Spiegelman D, Afonne C, Falade CO, Jegede AS, Oshiname FO, Gomes M, Ajayi IO | Implementation science : IS | 32131852 | Implement Sci | 2020 Mar 4 |
Structural, interpersonal, psychosocial, and behavioral risk factors for HIV acquisition among female bar workers in Dar es Salaam, Tanzania. | Barnhart DA, Harling G, Muya A, Ortblad KF, Mashasi I, Dambach P, Ulenga N, Mboggo E, Oldenburg CE, Bärnighausen TW, Spiegelman D | AIDS care | 31079476 | AIDS Care | 2019 Sep |
Drivers of healthy eating in a workplace in Nepal: a qualitative study. | Tamrakar D, Shrestha A, Rai A, Karmacharya BM, Malik V, Mattei J, Spiegelman D | BMJ open | 32102804 | BMJ Open | 2020 Feb 25 |
"Cross-sectional" stepped wedge designs always reduce the required sample size when there is no time effect. | Zhou X, Liao X, Spiegelman D | Journal of clinical epidemiology | 28093263 | J Clin Epidemiol | 2017 Mar |
Nepal Pioneer Worksite Intervention Study to lower cardio-metabolic risk factors: design and protocol. | Shrestha A, Tamrakar D, Karmacharya BM, Shrestha A, Shrestha R, Bhatta RD, Pyakurel P, Khudyakov P, Malik V, Mattei J, Spiegelman D | BMC cardiovascular disorders | 30819098 | BMC Cardiovasc Disord | 2019 Feb 28 |
Spiegelman and Zhou Respond. | Spiegelman D, Zhou X | American journal of public health | 30726133 | Am J Public Health | 2019 Mar |
Estimation and Inference for the Mediation Proportion. | Nevo D, Liao X, Spiegelman D | The international journal of biostatistics | 28930628 | Int J Biostat | 2017 Sep 20 |
Dietary interventions to prevent and manage diabetes in worksite settings: a meta-analysis. | Shrestha A, Karmacharya BM, Khudyakov P, Weber MB, Spiegelman D | Journal of occupational health | 29187673 | J Occup Health | 2018 Jan 25 |
Estimation in the Cox survival regression model with covariate measurement error and a changepoint. | Agami S, Zucker DM, Spiegelman D | Biometrical journal. Biometrische Zeitschrift | 32003495 | Biom J | 2020 Sep |
Impact of the Affordable Care Act on Colorectal Cancer Outcomes: A Systematic Review. | Xu MR, Kelly AMB, Kushi LH, Reed ME, Koh HK, Spiegelman D | American journal of preventive medicine | 32008799 | Am J Prev Med | 2020 Apr |
Evaluating Public Health Interventions: 8. Causal Inference for Time-Invariant Interventions. | Spiegelman D, Zhou X | American journal of public health | 30024804 | Am J Public Health | 2018 Sep |
Assessing Individual and Disseminated Effects in Network-Randomized Studies. | Buchanan AL, Vermund SH, Friedman SR, Spiegelman D | American journal of epidemiology | 30052722 | Am J Epidemiol | 2018 Nov 1 |
Health system measurement: Harnessing machine learning to advance global health. | Leslie HH, Zhou X, Spiegelman D, Kruk ME | PloS one | 30289935 | PLoS One | 2018 |
Diet and Health - What Should We Eat ? | Shrestha A, Spiegelman D | Kathmandu University medical journal (KUMJ) | 30353891 | Kathmandu Univ Med J (KUMJ) | 2017 Jul-Sept. |
The effect of risk factor misclassification on the partial population attributable risk. | Wong BHW, Peskoe SB, Spiegelman D | Statistics in medicine | 29333614 | Stat Med | 2018 Apr 15 |
Prevalence estimation when disease status is verified only among test positives: Applications in HIV screening programs. | G Thomas E, B Peskoe S, Spiegelman D | Statistics in medicine | 29230839 | Stat Med | 2018 Mar 30 |
ANALYSIS OF "LEARN-AS-YOU-GO" (LAGO) STUDIES. | Nevo D, Lok JJ, Spiegelman D | Annals of statistics | 35510045 | Ann Stat | 2021 Apr |
Intra-Cluster Correlation Estimates for HIV-related Outcomes from Care and Treatment Clinics in Dar es Salaam, Tanzania. | Barnhart D, Hertzmark E, Liu E, Mungure E, Muya AN, Sando D, Chalamilla G, Ulenga N, Bärnighausen T, Fawzi W, Spiegelman D | Contemporary clinical trials communications | 27766318 | Contemp Clin Trials Commun | 2016 Dec 15 |
Assessing Direct and Spillover Effects of Intervention Packages in Network-randomized Studies. | Buchanan AL, Hernández-Ramírez RU, Lok JJ, Vermund SH, Friedman SR, Forastiere L, Spiegelman D | Epidemiology (Cambridge, Mass.) | 38709023 | Epidemiology | 2024 Jul 1 |
Transcriptome-wide Analysis of Roles for tRNA Modifications in Translational Regulation. | Chou HJ, Donnard E, Gustafsson HT, Garber M, Rando OJ | Molecular cell | 29198561 | Mol Cell | 2017 Dec 7 |
Deficient spermiogenesis in mice lacking Rlim. | Wang F, Gervasi MG, Bošković A, Sun F, Rinaldi VD, Yu J, Wallingford MC, Tourzani DA, Mager J, Zhu LJ, Rando OJ, Visconti PE, Strittmatter L, Bach I | eLife | 33620316 | Elife | 2021 Feb 23 |
Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals. | Sharma U, Conine CC, Shea JM, Boskovic A, Derr AG, Bing XY, Belleannee C, Kucukural A, Serra RW, Sun F, Song L, Carone BR, Ricci EP, Li XZ, Fauquier L, Moore MJ, Sullivan R, Mello CC, Garber M, Rando OJ | Science (New York, N.Y.) | 26721685 | Science | 2016 Jan 22 |
Regulation of X-linked gene expression during early mouse development by Rlim. | Wang F, Shin J, Shea JM, Yu J, Bošković A, Byron M, Zhu X, Shalek AK, Regev A, Lawrence JB, Torres EM, Zhu LJ, Rando OJ, Bach I | eLife | 27642011 | Elife | 2016 Sep 19 |
Genetic and Epigenetic Variation, but Not Diet, Shape the Sperm Methylome. | Shea JM, Serra RW, Carone BR, Shulha HP, Kucukural A, Ziller MJ, Vallaster MP, Gu H, Tapper AR, Gardner PD, Meissner A, Garber M, Rando OJ | Developmental cell | 26702833 | Dev Cell | 2015 Dec 21 |
Small RNAs Are Trafficked from the Epididymis to Developing Mammalian Sperm. | Sharma U, Sun F, Conine CC, Reichholf B, Kukreja S, Herzog VA, Ameres SL, Rando OJ | Developmental cell | 30057273 | Dev Cell | 2018 Aug 20 |
Small RNAs Gained during Epididymal Transit of Sperm Are Essential for Embryonic Development in Mice. | Conine CC, Sun F, Song L, Rivera-Pérez JA, Rando OJ | Developmental cell | 30057276 | Dev Cell | 2018 Aug 20 |
Rlim-Dependent and -Independent Pathways for X Chromosome Inactivation in Female ESCs. | Wang F, McCannell KN, Bošković A, Zhu X, Shin J, Yu J, Gallant J, Byron M, Lawrence JB, Zhu LJ, Jones SN, Rando OJ, Fazzio TG, Bach I | Cell reports | 29281819 | Cell Rep | 2017 Dec 26 |
Father-son chats: inheriting stress through sperm RNA. | Sharma U, Rando OJ | Cell metabolism | 24896534 | Cell Metab | 2014 Jun 3 |
I'm eating for two: parental dietary effects on offspring metabolism. | Rando OJ, Simmons RA | Cell | 25815988 | Cell | 2015 Mar 26 |
High-throughput screening and classification of chemicals and their effects on neuronal gene expression using RASL-seq. | Simon JM, Paranjape SR, Wolter JM, Salazar G, Zylka MJ | Scientific reports | 30872602 | Sci Rep | 2019 Mar 14 |
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A deep neural network to assess spontaneous pain from mouse facial expressions. | Tuttle AH, Molinaro MJ, Jethwa JF, Sotocinal SG, Prieto JC, Styner MA, Mogil JS, Zylka MJ | Molecular pain | 29546805 | Mol Pain | 2018 Jan-Dec |
The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome. | Yi JJ, Paranjape SR, Walker MP, Choudhury R, Wolter JM, Fragola G, Emanuele MJ, Major MB, Zylka MJ | The Journal of biological chemistry | 28559284 | J Biol Chem | 2017 Jul 28 |
Gene length matters in neurons. | Zylka MJ, Simon JM, Philpot BD | Neuron | 25905808 | Neuron | 2015 Apr 22 |
An Autism-Linked Mutation Disables Phosphorylation Control of UBE3A. | Yi JJ, Berrios J, Newbern JM, Snider WD, Philpot BD, Hahn KM, Zylka MJ | Cell | 26255772 | Cell | 2015 Aug 13 |
Choice of vehicle affects pyraclostrobin toxicity in mice. | Tuttle AH, Salazar G, Cooper EM, Stapleton HM, Zylka MJ | Chemosphere | 30497033 | Chemosphere | 2019 Mar |
Single-cell transcriptomic analysis of mouse neocortical development. | Loo L, Simon JM, Xing L, McCoy ES, Niehaus JK, Guo J, Anton ES, Zylka MJ | Nature communications | 30635555 | Nat Commun | 2019 Jan 11 |
The Troubled Touch of Autism. | Tuttle AH, Bartsch VB, Zylka MJ | Cell | 27419865 | Cell | 2016 Jul 14 |
Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration. | Pearson BL, Simon JM, McCoy ES, Salazar G, Fragola G, Zylka MJ | Nature communications | 27029645 | Nat Commun | 2016 Mar 31 |
Topoisomerase 1 inhibition reversibly impairs synaptic function. | Mabb AM, Kullmann PH, Twomey MA, Miriyala J, Philpot BD, Zylka MJ | Proceedings of the National Academy of Sciences of the United States of America | 25404338 | Proc Natl Acad Sci U S A | 2014 Dec 2 |
lncRNA-Induced Spread of Polycomb Controlled by Genome Architecture, RNA Abundance, and CpG Island DNA. | Schertzer MD, Braceros KCA, Starmer J, Cherney RE, Lee DM, Salazar G, Justice M, Bischoff SR, Cowley DO, Ariel P, Zylka MJ, Dowen JM, Magnuson T, Calabrese JM | Molecular cell | 31256989 | Mol Cell | 2019 Aug 8 |
Toward a conceptual framework for early brain and behavior development in autism. | Piven J, Elison JT, Zylka MJ | Molecular psychiatry | 28937691 | Mol Psychiatry | 2017 Oct |
Chd8 haploinsufficiency impairs early brain development and protein homeostasis later in life. | Jiménez JA, Ptacek TS, Tuttle AH, Schmid RS, Moy SS, Simon JM, Zylka MJ | Molecular autism | 33023670 | Mol Autism | 2020 Oct 5 |
Deletion of Topoisomerase 1 in excitatory neurons causes genomic instability and early onset neurodegeneration. | Fragola G, Mabb AM, Taylor-Blake B, Niehaus JK, Chronister WD, Mao H, Simon JM, Yuan H, Li Z, McConnell MJ, Zylka MJ | Nature communications | 32327659 | Nat Commun | 2020 Apr 23 |
Maternal Ube3a Loss Disrupts Sleep Homeostasis But Leaves Circadian Rhythmicity Largely Intact. | Ehlen JC, Jones KA, Pinckney L, Gray CL, Burette S, Weinberg RJ, Evans JA, Brager AJ, Zylka MJ, Paul KN, Philpot BD, DeBruyne JP | The Journal of neuroscience : the official journal of the Society for Neuroscience | 26446213 | J Neurosci | 2015 Oct 7 |
Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms. | Mabb AM, Simon JM, King IF, Lee HM, An LK, Philpot BD, Zylka MJ | PloS one | 27231886 | PLoS One | 2016 |
Enhanced Nociception in Angelman Syndrome Model Mice. | McCoy ES, Taylor-Blake B, Aita M, Simon JM, Philpot BD, Zylka MJ | The Journal of neuroscience : the official journal of the Society for Neuroscience | 28931574 | J Neurosci | 2017 Oct 18 |
Determinants of Adiposity Rebound Timing in Children. | Ip EH, Marshall SA, Saldana S, Skelton JA, Suerken CK, Arcury TA, Quandt SA | The Journal of pediatrics | 28242030 | J Pediatr | 2017 May |
Mouse-human experimental epigenetic analysis unmasks dietary targets and genetic liability for diabetic phenotypes. | Multhaup ML, Seldin MM, Jaffe AE, Lei X, Kirchner H, Mondal P, Li Y, Rodriguez V, Drong A, Hussain M, Lindgren C, McCarthy M, Näslund E, Zierath JR, Wong GW, Feinberg AP | Cell metabolism | 25565211 | Cell Metab | 2015 Jan 6 |
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DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis. | Kular L, Liu Y, Ruhrmann S, Zheleznyakova G, Marabita F, Gomez-Cabrero D, James T, Ewing E, Lindén M, Górnikiewicz B, Aeinehband S, Stridh P, Link J, Andlauer TFM, Gasperi C, Wiendl H, Zipp F, Gold R, Tackenberg B, Weber F, Hemmer B, Strauch K, Heilmann-Heimbach S, Rawal R, Schminke U, Schmidt CO, Kacprowski T, Franke A, Laudes M, Dilthey AT, Celius EG, Søndergaard HB, Tegnér J, Harbo HF, Oturai AB, Olafsson S, Eggertsson HP, Halldorsson BV, Hjaltason H, Olafsson E, Jonsdottir I, Stefansson K, Olsson T, Piehl F, Ekström TJ, Kockum I, Feinberg AP, Jagodic M | Nature communications | 29921915 | Nat Commun | 2018 Jun 19 |
Potential energy landscapes identify the information-theoretic nature of the epigenome. | Jenkinson G, Pujadas E, Goutsias J, Feinberg AP | Nature genetics | 28346445 | Nat Genet | 2017 May |
Accurate proteome-wide protein quantification from high-resolution 15N mass spectra. | Khan Z, Amini S, Bloom JS, Ruse C, Caudy AA, Kruglyak L, Singh M, Perlman DH, Tavazoie S | Genome biology | 22182234 | Genome Biol | 2011 Dec 19 |
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Bacterial adaptation through loss of function. | Hottes AK, Freddolino PL, Khare A, Donnell ZN, Liu JC, Tavazoie S | PLoS genetics | 23874220 | PLoS Genet | 2013 |
Stochastic tuning of gene expression enables cellular adaptation in the absence of pre-existing regulatory circuitry. | Freddolino L, Yang J, Momen-Roknabadi A, Tavazoie S | eLife | 29620524 | Elife | 2018 Apr 5 |
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Genetically Determined Later Puberty Impacts Lowered Bone Mineral Density in Childhood and Adulthood. | Cousminer DL, Mitchell JA, Chesi A, Roy SM, Kalkwarf HJ, Lappe JM, Gilsanz V, Oberfield SE, Shepherd JA, Kelly A, McCormack SE, Voight BF, Zemel BS, Grant SF | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research | 29068475 | J Bone Miner Res | 2018 Mar |
Higher frequency of genetic variants conferring increased risk for ADRs for commonly used drugs treating cancer, AIDS and tuberculosis in persons of African descent. | Aminkeng F, Ross CJ, Rassekh SR, Brunham LR, Sistonen J, Dube MP, Ibrahim M, Nyambo TB, Omar SA, Froment A, Bodo JM, Tishkoff S, Carleton BC, Hayden MR, Canadian Pharmacogenomics Network for Drug Safety Consortium | The pharmacogenomics journal | 23588107 | Pharmacogenomics J | 2014 Apr |
Going global by adapting local: A review of recent human adaptation. | Fan S, Hansen ME, Lo Y, Tishkoff SA | Science (New York, N.Y.) | 27846491 | Science | 2016 Oct 7 |
Shorter telomere length in Europeans than in Africans due to polygenetic adaptation. | Hansen ME, Hunt SC, Stone RC, Horvath K, Herbig U, Ranciaro A, Hirbo J, Beggs W, Reiner AP, Wilson JG, Kimura M, De Vivo I, Chen MM, Kark JD, Levy D, Nyambo T, Tishkoff SA, Aviv A | Human molecular genetics | 26936823 | Hum Mol Genet | 2016 Jun 1 |
Regulation of amyloid-β dynamics and pathology by the circadian clock. | Kress GJ, Liao F, Dimitry J, Cedeno MR, FitzGerald GA, Holtzman DM, Musiek ES | The Journal of experimental medicine | 29382695 | J Exp Med | 2018 Apr 2 |
Genetic origins of lactase persistence and the spread of pastoralism in Africa. | Ranciaro A, Campbell MC, Hirbo JB, Ko WY, Froment A, Anagnostou P, Kotze MJ, Ibrahim M, Nyambo T, Omar SA, Tishkoff SA | American journal of human genetics | 24630847 | Am J Hum Genet | 2014 Apr 3 |
Great ape genetic diversity and population history. | Prado-Martinez J, Sudmant PH, Kidd JM, Li H, Kelley JL, Lorente-Galdos B, Veeramah KR, Woerner AE, O'Connor TD, Santpere G, Cagan A, Theunert C, Casals F, Laayouni H, Munch K, Hobolth A, Halager AE, Malig M, Hernandez-Rodriguez J, Hernando-Herraez I, Prüfer K, Pybus M, Johnstone L, Lachmann M, Alkan C, Twigg D, Petit N, Baker C, Hormozdiari F, Fernandez-Callejo M, Dabad M, Wilson ML, Stevison L, Camprubí C, Carvalho T, Ruiz-Herrera A, Vives L, Mele M, Abello T, Kondova I, Bontrop RE, Pusey A, Lankester F, Kiyang JA, Bergl RA, Lonsdorf E, Myers S, Ventura M, Gagneux P, Comas D, Siegismund H, Blanc J, Agueda-Calpena L, Gut M, Fulton L, Tishkoff SA, Mullikin JC, Wilson RK, Gut IG, Gonder MK, Ryder OA, Hahn BH, Navarro A, Akey JM, Bertranpetit J, Reich D, Mailund T, Schierup MH, Hvilsom C, Andrés AM, Wall JD, Bustamante CD, Hammer MF, Eichler EE, Marques-Bonet T | Nature | 23823723 | Nature | 2013 Jul 25 |
Origin and differential selection of allelic variation at TAS2R16 associated with salicin bitter taste sensitivity in Africa. | Campbell MC, Ranciaro A, Zinshteyn D, Rawlings-Goss R, Hirbo J, Thompson S, Woldemeskel D, Froment A, Rucker JB, Omar SA, Bodo JM, Nyambo T, Belay G, Drayna D, Breslin PA, Tishkoff SA | Molecular biology and evolution | 24177185 | Mol Biol Evol | 2014 Feb |
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Genome-wide patterns of population structure and admixture in West Africans and African Americans. | Bryc K, Auton A, Nelson MR, Oksenberg JR, Hauser SL, Williams S, Froment A, Bodo JM, Wambebe C, Tishkoff SA, Bustamante CD | Proceedings of the National Academy of Sciences of the United States of America | 20080753 | Proc Natl Acad Sci U S A | 2010 Jan 12 |
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The Sustained Impact of Model Organisms-in Genetics and Epigenetics. | Bonini NM, Berger SL | Genetics | 28049700 | Genetics | 2017 Jan |
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Model-based analyses of whole-genome data reveal a complex evolutionary history involving archaic introgression in Central African Pygmies. | Hsieh P, Woerner AE, Wall JD, Lachance J, Tishkoff SA, Gutenkunst RN, Hammer MF | Genome research | 26888264 | Genome Res | 2016 Mar |
Population structure of human gut bacteria in a diverse cohort from rural Tanzania and Botswana. | Hansen MEB, Rubel MA, Bailey AG, Ranciaro A, Thompson SR, Campbell MC, Beggs W, Dave JR, Mokone GG, Mpoloka SW, Nyambo T, Abnet C, Chanock SJ, Bushman FD, Tishkoff SA | Genome biology | 30665461 | Genome Biol | 2019 Jan 22 |
The genetic prehistory of southern Africa. | Pickrell JK, Patterson N, Barbieri C, Berthold F, Gerlach L, Güldemann T, Kure B, Mpoloka SW, Nakagawa H, Naumann C, Lipson M, Loh PR, Lachance J, Mountain J, Bustamante CD, Berger B, Tishkoff SA, Henn BM, Stoneking M, Reich D, Pakendorf B | Nature communications | 23072811 | Nat Commun | 2012 |
Apparent variation in Neanderthal admixture among African populations is consistent with gene flow from Non-African populations. | Wang S, Lachance J, Tishkoff SA, Hey J, Xing J | Genome biology and evolution | 24162011 | Genome Biol Evol | 2013 |
SNP ascertainment bias in population genetic analyses: why it is important, and how to correct it. | Lachance J, Tishkoff SA | BioEssays : news and reviews in molecular, cellular and developmental biology | 23836388 | Bioessays | 2013 Sep |
Whole-genome sequence analyses of Western Central African Pygmy hunter-gatherers reveal a complex demographic history and identify candidate genes under positive natural selection. | Hsieh P, Veeramah KR, Lachance J, Tishkoff SA, Wall JD, Hammer MF, Gutenkunst RN | Genome research | 26888263 | Genome Res | 2016 Mar |
Sequence diversity of Pan troglodytes subspecies and the impact of WFDC6 selective constraints in reproductive immunity. | Ferreira Z, Hurle B, Andrés AM, Kretzschmar WW, Mullikin JC, Cherukuri PF, Cruz P, Gonder MK, Stone AC, Tishkoff S, Swanson WJ, NISC Comparative Sequencing Program, Green ED, Clark AG, Seixas S | Genome biology and evolution | 24356879 | Genome Biol Evol | 2013 |
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Global diversity, population stratification, and selection of human copy-number variation. | Sudmant PH, Mallick S, Nelson BJ, Hormozdiari F, Krumm N, Huddleston J, Coe BP, Baker C, Nordenfelt S, Bamshad M, Jorde LB, Posukh OL, Sahakyan H, Watkins WS, Yepiskoposyan L, Abdullah MS, Bravi CM, Capelli C, Hervig T, Wee JT, Tyler-Smith C, van Driem G, Romero IG, Jha AR, Karachanak-Yankova S, Toncheva D, Comas D, Henn B, Kivisild T, Ruiz-Linares A, Sajantila A, Metspalu E, Parik J, Villems R, Starikovskaya EB, Ayodo G, Beall CM, Di Rienzo A, Hammer MF, Khusainova R, Khusnutdinova E, Klitz W, Winkler C, Labuda D, Metspalu M, Tishkoff SA, Dryomov S, Sukernik R, Patterson N, Reich D, Eichler EE | Science (New York, N.Y.) | 26249230 | Science | 2015 Sep 11 |
Genetic adaptation to high altitude in the Ethiopian highlands. | Scheinfeldt LB, Soi S, Thompson S, Ranciaro A, Woldemeskel D, Beggs W, Lambert C, Jarvis JP, Abate D, Belay G, Tishkoff SA | Genome biology | 22264333 | Genome Biol | 2012 Jan 20 |
Evolutionary history and adaptation from high-coverage whole-genome sequences of diverse African hunter-gatherers. | Lachance J, Vernot B, Elbers CC, Ferwerda B, Froment A, Bodo JM, Lema G, Fu W, Nyambo TB, Rebbeck TR, Zhang K, Akey JM, Tishkoff SA | Cell | 22840920 | Cell | 2012 Aug 3 |
Structural diversity and African origin of the 17q21.31 inversion polymorphism. | Steinberg KM, Antonacci F, Sudmant PH, Kidd JM, Campbell CD, Vives L, Malig M, Scheinfeldt L, Beggs W, Ibrahim M, Lema G, Nyambo TB, Omar SA, Bodo JM, Froment A, Donnelly MP, Kidd KK, Tishkoff SA, Eichler EE | Nature genetics | 22751100 | Nat Genet | 2012 Jul 1 |
Identifying Darwinian selection acting on different human APOL1 variants among diverse African populations. | Ko WY, Rajan P, Gomez F, Scheinfeldt L, An P, Winkler CA, Froment A, Nyambo TB, Omar SA, Wambebe C, Ranciaro A, Hirbo JB, Tishkoff SA | American journal of human genetics | 23768513 | Am J Hum Genet | 2013 Jul 11 |
Biased gene conversion skews allele frequencies in human populations, increasing the disease burden of recessive alleles. | Lachance J, Tishkoff SA | American journal of human genetics | 25279983 | Am J Hum Genet | 2014 Oct 2 |
Extraction and Analysis of Pan-metabolome Polar Metabolites by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS). | Malik DM, Rhoades S, Weljie A | Bio-protocol | 29623284 | Bio Protoc | 2018 Feb 5 |
Genetic Hitchhiking and Population Bottlenecks Contribute to Prostate Cancer Disparities in Men of African Descent. | Lachance J, Berens AJ, Hansen MEB, Teng AK, Tishkoff SA, Rebbeck TR | Cancer research | 29438991 | Cancer Res | 2018 May 1 |
The peopling of the African continent and the diaspora into the new world. | Campbell MC, Hirbo JB, Townsend JP, Tishkoff SA | Current opinion in genetics & development | 25461616 | Curr Opin Genet Dev | 2014 Dec |
Limited evidence for adaptive evolution and functional effect of allelic variation at rs702424 in the promoter of the TAS2R16 bitter taste receptor gene in Africa. | Campbell MC, Ranciaro A, Zinshteyn D, Rawlings-Goss R, Hirbo J, Thompson S, Woldemeskel D, Froment A, Omar SA, Bodo JM, Nyambo T, Belay G, Drayna D, Breslin PA, Tishkoff SA | Journal of human genetics | 24785689 | J Hum Genet | 2014 Jun |
A Locus at 5q33.3 Confers Resistance to Tuberculosis in Highly Susceptible Individuals. | Sobota RS, Stein CM, Kodaman N, Scheinfeldt LB, Maro I, Wieland-Alter W, Igo RP Jr, Magohe A, Malone LL, Chervenak K, Hall NB, Modongo C, Zetola N, Matee M, Joloba M, Froment A, Nyambo TB, Moore JH, Scott WK, Lahey T, Boom WH, von Reyn CF, Tishkoff SA, Sirugo G, Williams SM | American journal of human genetics | 26942285 | Am J Hum Genet | 2016 Mar 3 |
Genomic analyses inform on migration events during the peopling of Eurasia. | Pagani L, Lawson DJ, Jagoda E, Mörseburg A, Eriksson A, Mitt M, Clemente F, Hudjashov G, DeGiorgio M, Saag L, Wall JD, Cardona A, Mägi R, Wilson Sayres MA, Kaewert S, Inchley C, Scheib CL, Järve M, Karmin M, Jacobs GS, Antao T, Iliescu FM, Kushniarevich A, Ayub Q, Tyler-Smith C, Xue Y, Yunusbayev B, Tambets K, Mallick CB, Saag L, Pocheshkhova E, Andriadze G, Muller C, Westaway MC, Lambert DM, Zoraqi G, Turdikulova S, Dalimova D, Sabitov Z, Sultana GNN, Lachance J, Tishkoff S, Momynaliev K, Isakova J, Damba LD, Gubina M, Nymadawa P, Evseeva I, Atramentova L, Utevska O, Ricaut FX, Brucato N, Sudoyo H, Letellier T, Cox MP, Barashkov NA, Skaro V, Mulahasanovic L, Primorac D, Sahakyan H, Mormina M, Eichstaedt CA, Lichman DV, Abdullah S, Chaubey G, Wee JTS, Mihailov E, Karunas A, Litvinov S, Khusainova R, Ekomasova N, Akhmetova V, Khidiyatova I, Marjanović D, Yepiskoposyan L, Behar DM, Balanovska E, Metspalu A, Derenko M, Malyarchuk B, Voevoda M, Fedorova SA, Osipova LP, Lahr MM, Gerbault P, Leavesley M, Migliano AB, Petraglia M, Balanovsky O, Khusnutdinova EK, Metspalu E, Thomas MG, Manica A, Nielsen R, Villems R, Willerslev E, Kivisild T, Metspalu M | Nature | 27654910 | Nature | 2016 Oct 13 |
Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis. | Nagel ZD, Margulies CM, Chaim IA, McRee SK, Mazzucato P, Ahmad A, Abo RP, Butty VL, Forget AL, Samson LD | Proceedings of the National Academy of Sciences of the United States of America | 24757057 | Proc Natl Acad Sci U S A | 2014 May 6 |
Fluorogenic Real-Time Reporters of DNA Repair by MGMT, a Clinical Predictor of Antitumor Drug Response. | Beharry AA, Nagel ZD, Samson LD, Kool ET | PloS one | 27035132 | PLoS One | 2016 |
Microcolony Size Distribution Assay Enables High-Throughput Cell Survival Quantitation. | Ngo LP, Chan TK, Ge J, Samson LD, Engelward BP | Cell reports | 30726746 | Cell Rep | 2019 Feb 5 |
DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma Multiforme. | Nagel ZD, Kitange GJ, Gupta SK, Joughin BA, Chaim IA, Mazzucato P, Lauffenburger DA, Sarkaria JN, Samson LD | Cancer research | 27793847 | Cancer Res | 2017 Jan 1 |
Towards precision prevention: Technologies for identifying healthy individuals with high risk of disease. | Nagel ZD, Engelward BP, Brenner DJ, Begley TJ, Sobol RW, Bielas JH, Stambrook PJ, Wei Q, Hu JJ, Terry MB, Dilworth C, McAllister KA, Reinlib L, Worth L, Shaughnessy DT | Mutation research | 28458064 | Mutat Res | 2017 Aug |
Single-cell analysis of ribonucleotide reductase transcriptional and translational response to DNA damage. | Mazumder A, Tummler K, Bathe M, Samson LD | Molecular and cellular biology | 23184665 | Mol Cell Biol | 2013 Feb |
CometChip analysis of human primary lymphocytes enables quantification of inter-individual differences in the kinetics of repair of oxidative DNA damage. | Ngo LP, Kaushal S, Chaim IA, Mazzucato P, Ricciardi C, Samson LD, Nagel ZD, Engelward BP | Free radical biology & medicine | 34324980 | Free Radic Biol Med | 2021 Oct |
Inter-individual variation in DNA repair capacity: a need for multi-pathway functional assays to promote translational DNA repair research. | Nagel ZD, Chaim IA, Samson LD | DNA repair | 24780560 | DNA Repair (Amst) | 2014 Jul |
In vivo measurements of interindividual differences in DNA glycosylases and APE1 activities. | Chaim IA, Nagel ZD, Jordan JJ, Mazzucato P, Ngo LP, Samson LD | Proceedings of the National Academy of Sciences of the United States of America | 29122935 | Proc Natl Acad Sci U S A | 2017 Nov 28 |
Minor Changes in Expression of the Mismatch Repair Protein MSH2 Exert a Major Impact on Glioblastoma Response to Temozolomide. | McFaline-Figueroa JL, Braun CJ, Stanciu M, Nagel ZD, Mazzucato P, Sangaraju D, Cerniauskas E, Barford K, Vargas A, Chen Y, Tretyakova N, Lees JA, Hemann MT, White FM, Samson LD | Cancer research | 26025730 | Cancer Res | 2015 Aug 1 |
Bioorthogonal Labeling Enables In Situ Fluorescence Imaging of Expressed Gas Vesicle Nanostructures. | Schrunk E, Dutka P, Hurt RC, Wu D, Shapiro MG | Bioconjugate chemistry | 38346316 | Bioconjug Chem | 2024 Mar 20 |
Biomolecular actuators for genetically selective acoustic manipulation of cells. | Wu D, Baresch D, Cook C, Ma Z, Duan M, Malounda D, Maresca D, Abundo MP, Lee J, Shivaei S, Mittelstein DR, Qiu T, Fischer P, Shapiro MG | Science advances | 36812320 | Sci Adv | 2023 Feb 22 |
A method for single-neuron chronic recording from the retina in awake mice. | Hong G, Fu TM, Qiao M, Viveros RD, Yang X, Zhou T, Lee JM, Park HG, Sanes JR, Lieber CM | Science (New York, N.Y.) | 29954976 | Science | 2018 Jun 29 |
Advanced One- and Two-Dimensional Mesh Designs for Injectable Electronics. | Viveros RD, Zhou T, Hong G, Fu TM, Lin HG, Lieber CM | Nano letters | 31075202 | Nano Lett | 2019 Jun 12 |
Tissue-like Neural Probes for Understanding and Modulating the Brain. | Hong G, Viveros RD, Zwang TJ, Yang X, Lieber CM | Biochemistry | 29529359 | Biochemistry | 2018 Jul 10 |
Mesh Nanoelectronics: Seamless Integration of Electronics with Tissues. | Dai X, Hong G, Gao T, Lieber CM | Accounts of chemical research | 29381054 | Acc Chem Res | 2018 Feb 20 |
Bioinspired neuron-like electronics. | Yang X, Zhou T, Zwang TJ, Hong G, Zhao Y, Viveros RD, Fu TM, Gao T, Lieber CM | Nature materials | 30804509 | Nat Mater | 2019 May |
Novel electrode technologies for neural recordings. | Hong G, Lieber CM | Nature reviews. Neuroscience | 30833706 | Nat Rev Neurosci | 2019 Jun |
Syringe-injectable Mesh Electronics for Stable Chronic Rodent Electrophysiology. | Schuhmann TG Jr, Zhou T, Hong G, Lee JM, Fu TM, Park HG, Lieber CM | Journal of visualized experiments : JoVE | 30080192 | J Vis Exp | 2018 Jul 21 |
Mesh electronics: a new paradigm for tissue-like brain probes. | Hong G, Yang X, Zhou T, Lieber CM | Current opinion in neurobiology | 29202327 | Curr Opin Neurobiol | 2018 Jun |
Precision electronic medicine in the brain. | Patel SR, Lieber CM | Nature biotechnology | 31477925 | Nat Biotechnol | 2019 Sep |
Nanoenabled Direct Contact Interfacing of Syringe-Injectable Mesh Electronics. | Lee JM, Hong G, Lin D, Schuhmann TG Jr, Sullivan AT, Viveros RD, Park HG, Lieber CM | Nano letters | 31361503 | Nano Lett | 2019 Aug 14 |
Nanowire-Enabled Bioelectronics. | Zhang A, Lee JH, Lieber CM | Nano today | 36970717 | Nano Today | 2021 Jun |
Nanowired Bioelectric Interfaces. | Tian B, Lieber CM | Chemical reviews | 30995019 | Chem Rev | 2019 Aug 14 |
Whispering-gallery-mode emission from biological luminescent protein microcavity assemblies. | Humar M, Yun SH | Optica | 29046889 | Optica | 2017 |
Conformal Coating of Freestanding Particles by Vapor-Phase Infiltration. | Liapis AC, Subramanian A, Cho S, Kisslinger K, Nam CY, Yun SH | Advanced materials interfaces | 33708471 | Adv Mater Interfaces | 2020 Dec 17 |
Light in diagnosis, therapy and surgery. | Yun SH, Kwok SJJ | Nature biomedical engineering | 28649464 | Nat Biomed Eng | 2017 |
Spectral reading of optical resonance-encoded cells in microfluidics. | Humar M, Upadhya A, Yun SH | Lab on a chip | 28686280 | Lab Chip | 2017 Aug 8 |
Submicrometer perovskite plasmonic lasers at room temperature. | Cho S, Yang Y, Soljačić M, Yun SH | Science advances | 34433555 | Sci Adv | 2021 Aug |
Non-destructive mapping of stress and strain in soft thin films through sound waves. | Li GY, Gower AL, Destrade M, Yun SH | Communications physics | 37744302 | Commun Phys | 2022 |
High-dimensional multi-pass flow cytometry via spectrally encoded cellular barcoding. | Kwok SJJ, Forward S, Fahlberg MD, Assita ER, Cosgriff S, Lee SH, Abbott GR, Zhu H, Minasian NH, Vote AS, Martino N, Yun SH | Nature biomedical engineering | 38036616 | Nat Biomed Eng | 2024 Mar |
Precise photoelectrochemical tuning of semiconductor microdisk lasers. | Sarkar D, Dannenberg PH, Martino N, Kim KH, Yun SH | Advanced photonics | 38993283 | Adv Photonics | 2023 Sep |
Laser Particle Stimulated Emission Microscopy. | Cho S, Humar M, Martino N, Yun SH | Physical review letters | 27858427 | Phys Rev Lett | 2016 Nov 4 |
Laser particles with omnidirectional emission for cell tracking. | Tang SJ, Dannenberg PH, Liapis AC, Martino N, Zhuo Y, Xiao YF, Yun SH | Light, science & applications | 33495436 | Light Sci Appl | 2021 Jan 25 |
Multiplexed laser particles for spatially resolved single-cell analysis. | Kwok SJJ, Martino N, Dannenberg PH, Yun SH | Light, science & applications | 31645920 | Light Sci Appl | 2019 |
Wavelength-encoded laser particles for massively multiplexed cell tagging. | Martino N, Kwok SJJ, Liapis AC, Forward S, Jang H, Kim HM, Wu SJ, Wu J, Dannenberg PH, Jang SJ, Lee YH, Yun SH | Nature photonics | 32231707 | Nat Photonics | 2019 Oct |
Supershear surface waves reveal prestress and anisotropy of soft materials. | Li GY, Feng X, Ramier A, Yun SH | Journal of the mechanics and physics of solids | 37828998 | J Mech Phys Solids | 2022 Dec |
Ultrasmall InGa(As)P Dielectric and Plasmonic Nanolasers. | Sarkar D, Cho S, Yan H, Martino N, Dannenberg PH, Yun SH | ACS nano | 37523588 | ACS Nano | 2023 Aug 22 |
Poly(catecholamine) coated CsPbBr(3) perovskite microlasers: lasing in water and biofunctionalization. | Cho S, Yun SH | Advanced functional materials | 34539305 | Adv Funct Mater | 2021 Jul 2 |
Biomaterial microlasers implantable in the cornea, skin, and blood. | Humar M, Dobravec A, Zhao X, Yun SH | Optica | 30333986 | Optica | 2017 Sep 20 |
Label-free histological imaging of tissues using Brillouin light scattering contrast. | Ryu S, Martino N, Kwok SJJ, Bernstein L, Yun SH | Biomedical optics express | 33796364 | Biomed Opt Express | 2021 Mar 1 |
Facile layer-by-layer fabrication of semiconductor microdisk laser particles. | Dannenberg PH, Liapis AC, Martino N, Sarkar D, Kim KH, Yun SH | APL photonics | 38031595 | APL Photonics | 2023 Feb |
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Droplet microfluidic generation of a million optical microparticle barcodes. | Dannenberg PH, Wang J, Zhuo Y, Cho S, Kim KH, Yun SH | Optics express | 34808870 | Opt Express | 2021 Nov 8 |
Laser particle activated cell sorting in microfluidics. | Dannenberg PH, Kang J, Martino N, Kashiparekh A, Forward S, Wu J, Liapis AC, Wang J, Yun SH | Lab on a chip | 35621381 | Lab Chip | 2022 Jun 14 |
Compact Quantum-Dot Microbeads with Sub-Nanometer Emission Linewidth. | Kim KH, Dannenberg PH, Yan H, Cho S, Yun SH | Advanced functional materials | 35418816 | Adv Funct Mater | 2021 Nov 25 |
Encrypted Three-dimensional Dynamic Imaging using Snapshot Time-of-flight Compressed Ultrafast Photography. | Liang J, Gao L, Hai P, Li C, Wang LV | Scientific reports | 26503834 | Sci Rep | 2015 Oct 27 |
Dual-Modality Photoacoustic and Ultrasound Imaging System for Noninvasive Sentinel Lymph Node Detection in Patients with Breast Cancer. | Garcia-Uribe A, Erpelding TN, Krumholz A, Ke H, Maslov K, Appleton C, Margenthaler JA, Wang LV | Scientific reports | 26510774 | Sci Rep | 2015 Oct 29 |
Cuffing-based photoacoustic flowmetry in humans in the optical diffusive regime. | Zhou Y, Liang J, Wang LV | Journal of biophotonics | 26515158 | J Biophotonics | 2016 Mar |
Single-shot real-time video recording of a photonic Mach cone induced by a scattered light pulse. | Liang J, Ma C, Zhu L, Chen Y, Gao L, Wang LV | Science advances | 28116357 | Sci Adv | 2017 Jan |
Focusing light through scattering media by polarization modulation based generalized digital optical phase conjugation. | Yang J, Shen Y, Liu Y, Hemphill AS, Wang LV | Applied physics letters | 29203931 | Appl Phys Lett | 2017 Nov 13 |
Transvaginal fast-scanning optical-resolution photoacoustic endoscopy. | Qu Y, Li C, Shi J, Chen R, Xu S, Rafsanjani H, Maslov K, Krigman H, Garvey L, Hu P, Zhao P, Meyers K, Diveley E, Pizzella S, Muench L, Punyamurthy N, Goldstein N, Onwumere O, Alisio M, Meyenburg K, Maynard J, Helm K, Slaughter J, Barber S, Burger T, Kramer C, Chubiz J, Anderson M, McCarthy R, England SK, Macones GA, Zhou Q, Shung KK, Zou J, Stout MJ, Tuuli M, Wang LV | Journal of biomedical optics | 30520276 | J Biomed Opt | 2018 Dec |
Angular-spectrum modeling of focusing light inside scattering media by optical phase conjugation. | Yang J, Li J, He S, Wang LV | Optica | 32025534 | Optica | 2019 Mar 20 |
Photoacoustic computed tomography of human extremities. | Wray P, Lin L, Hu P, Wang LV | Journal of biomedical optics | 30784244 | J Biomed Opt | 2019 Feb |
Single-shot ultrafast optical imaging. | Liang J, Wang LV | Optica | 30820445 | Optica | 2018 Sep 20 |
Multifocal photoacoustic microscopy using a single-element ultrasonic transducer through an ergodic relay. | Li Y, Wong TTW, Shi J, Hsu HC, Wang LV | Light, science & applications | 32793336 | Light Sci Appl | 2020 |
High-resolution, high-contrast mid-infrared imaging of fresh biological samples with ultraviolet-localized photoacoustic microscopy. | Shi J, Wong TTW, He Y, Li L, Zhang R, Yung CS, Hwang J, Maslov K, Wang LV | Nature photonics | 31440304 | Nat Photonics | 2019 Sep |
Single-shot stereo-polarimetric compressed ultrafast photography for light-speed observation of high-dimensional optical transients with picosecond resolution. | Liang J, Wang P, Zhu L, Wang LV | Nature communications | 33067438 | Nat Commun | 2020 Oct 16 |
Delivery of AAV for Expression of Fluorescent Biosensors in Juvenile Mouse Hippocampus. | Díaz-García CM, Nathwani N, Martínez-François JR, Yellen G | Bio-protocol | 35087918 | Bio Protoc | 2021 Dec 20 |
High-sensitivity ultrasound-modulated optical tomography with a photorefractive polymer. | Suzuki Y, Lai P, Xu X, Wang L | Optics letters | 23503253 | Opt Lett | 2013 Mar 15 |
Photoacoustic recovery after photothermal bleaching in living cells. | Li C, Zhang C, Gao L, Garcia-Uribe A, Wang LV | Journal of biomedical optics | 24089253 | J Biomed Opt | 2013 Oct |
Photoacoustic measurement of the Grüneisen parameter of tissue. | Yao DK, Zhang C, Maslov K, Wang LV | Journal of biomedical optics | 24474512 | J Biomed Opt | 2014 Jan |
Multicontrast photoacoustic in vivo imaging using near-infrared fluorescent proteins. | Krumholz A, Shcherbakova DM, Xia J, Wang LV, Verkhusha VV | Scientific reports | 24487319 | Sci Rep | 2014 Feb 3 |
Spatially Fourier-encoded photoacoustic microscopy using a digital micromirror device. | Liang J, Gao L, Li C, Wang LV | Optics letters | 24487832 | Opt Lett | 2014 Feb 1 |
Three-dimensional arbitrary trajectory scanning photoacoustic microscopy. | Yeh C, Soetikno B, Hu S, Maslov KI, Wang LV | Journal of biophotonics | 25077689 | J Biophotonics | 2015 Apr |
In vivo optically encoded photoacoustic flowgraphy. | Zhang R, Wang L, Yao J, Yeh CH, Wang LV | Optics letters | 24978744 | Opt Lett | 2014 Jul 1 |
Continuous scanning of a time-reversed ultrasonically encoded optical focus by reflection-mode digital phase conjugation. | Suzuki Y, Tay JW, Yang Q, Wang LV | Optics letters | 24978506 | Opt Lett | 2014 Jun 15 |
Photoacoustic tomography: principles and advances. | Xia J, Yao J, Wang LV | Electromagnetic waves (Cambridge, Mass.) | 25642127 | Electromagn Waves (Camb) | 2014 |
Optical drug monitoring: photoacoustic imaging of nanosensors to monitor therapeutic lithium in vivo. | Cash KJ, Li C, Xia J, Wang LV, Clark HA | ACS nano | 25588028 | ACS Nano | 2015 Feb 24 |
Single-shot compressed ultrafast photography at one hundred billion frames per second. | Gao L, Liang J, Li C, Wang LV | Nature | 25471883 | Nature | 2014 Dec 4 |
Photoacoustic tomography imaging and estimation of oxygen saturation of hemoglobin in ocular tissue of rabbits. | Hennen SN, Xing W, Shui YB, Zhou Y, Kalishman J, Andrews-Kaminsky LB, Kass MA, Beebe DC, Maslov KI, Wang LV | Experimental eye research | 26048477 | Exp Eye Res | 2015 Sep |
Multiview Hilbert transformation for full-view photoacoustic computed tomography using a linear array. | Li G, Li L, Zhu L, Xia J, Wang LV | Journal of biomedical optics | 26112369 | J Biomed Opt | 2015 Jun |
Handheld optical-resolution photoacoustic microscopy. | Lin L, Zhang P, Xu S, Shi J, Li L, Yao J, Wang L, Zou J, Wang LV | Journal of biomedical optics | 27775746 | J Biomed Opt | 2017 Apr 1 |
Wide-field two-dimensional multifocal optical-resolution photoacoustic-computed microscopy. | Xia J, Li G, Wang L, Nasiriavanaki M, Maslov K, Engelbach JA, Garbow JR, Wang LV | Optics letters | 24322226 | Opt Lett | 2013 Dec 15 |
Retrospective respiration-gated whole-body photoacoustic computed tomography of mice. | Xia J, Chen W, Maslov K, Anastasio MA, Wang LV | Journal of biomedical optics | 24395586 | J Biomed Opt | 2014 Jan |
Focusing light inside dynamic scattering media with millisecond digital optical phase conjugation. | Liu Y, Ma C, Shen Y, Shi J, Wang LV | Optica | 28815194 | Optica | 2017 Feb |
Sub-Nyquist sampling boosts targeted light transport through opaque scattering media. | Shen Y, Liu Y, Ma C, Wang LV | Optica | 28670607 | Optica | 2017 Jan 20 |
Optical clearing-aided photoacoustic microscopy with enhanced resolution and imaging depth. | Zhou Y, Yao J, Wang LV | Optics letters | 23939121 | Opt Lett | 2013 Jul 15 |
Deep-tissue photoacoustic tomography of Förster resonance energy transfer. | Wang Y, Xia J, Wang LV | Journal of biomedical optics | 23884608 | J Biomed Opt | 2013 Oct |
Random-access optical-resolution photoacoustic microscopy using a digital micromirror device. | Liang J, Zhou Y, Winkler AW, Wang L, Maslov KI, Li C, Wang LV | Optics letters | 23903111 | Opt Lett | 2013 Aug 1 |
Time-reversed ultrasonically encoded optical focusing using two ultrasonic transducers for improved ultrasonic axial resolution. | Yang Q, Xu X, Lai P, Xu D, Wang LV | Journal of biomedical optics | 24194060 | J Biomed Opt | 2013 Nov |
Ultrasound-heated photoacoustic flowmetry. | Wang L, Yao J, Maslov KI, Xing W, Wang LV | Journal of biomedical optics | 24194064 | J Biomed Opt | 2013 Nov |
Urogenital photoacoustic endoscope. | Li C, Yang JM, Chen R, Yeh CH, Zhu L, Maslov K, Zhou Q, Shung KK, Wang LV | Optics letters | 24690816 | Opt Lett | 2014 Mar 15 |
Calibration-free absolute quantification of particle concentration by statistical analyses of photoacoustic signals in vivo. | Zhou Y, Yao J, Maslov KI, Wang LV | Journal of biomedical optics | 24589987 | J Biomed Opt | 2014 Mar |
Photoacoustically guided wavefront shaping for enhanced optical focusing in scattering media. | Lai P, Wang L, Tay JW, Wang LV | Nature photonics | 25914725 | Nat Photonics | 2015 Feb |
In vivo photoacoustic flowmetry at depths of the diffusive regime based on saline injection. | Zhou Y, Poudel J, Li G, Wang LV | Journal of biomedical optics | 26267364 | J Biomed Opt | 2015 Aug |
Picosecond-resolution phase-sensitive imaging of transparent objects in a single shot. | Kim T, Liang J, Zhu L, Wang LV | Science advances | 32010772 | Sci Adv | 2020 Jan |
Dual-axis illumination for virtually augmenting the detection view of optical-resolution photoacoustic microscopy. | Hsu HC, Li L, Yao J, Wong TTW, Shi J, Chen R, Zhou Q, Wang L | Journal of biomedical optics | 29981225 | J Biomed Opt | 2018 Jul |
High-speed alignment optimization of digital optical phase conjugation systems based on autocovariance analysis in conjunction with orthonormal rectangular polynomials. | Hemphill AS, Shen Y, Hwang J, Wang LV | Journal of biomedical optics | 30156064 | J Biomed Opt | 2018 Aug |
Optical-resolution photoacoustic endomicroscopy in vivo. | Yang JM, Li C, Chen R, Rao B, Yao J, Yeh CH, Danielli A, Maslov K, Zhou Q, Shung KK, Wang LV | Biomedical optics express | 25798315 | Biomed Opt Express | 2015 Mar 1 |
Ultrasonic-heating-encoded photoacoustic tomography with virtually augmented detection view. | Wang L, Li G, Xia J, Wang LV | Optica | 25984555 | Optica | 2015 |
Slow-sound photoacoustic microscopy. | Zhang C, Zhou Y, Li C, Wang LV | Applied physics letters | 23696693 | Appl Phys Lett | 2013 Apr 22 |
Calibration-free in vivo transverse blood flowmetry based on cross correlation of slow time profiles from photoacoustic microscopy. | Zhou Y, Liang J, Maslov KI, Wang LV | Optics letters | 24081077 | Opt Lett | 2013 Oct 1 |
Intracellular temperature mapping with fluorescence-assisted photoacoustic-thermometry. | Gao L, Zhang C, Li C, Wang LV | Applied physics letters | 23825801 | Appl Phys Lett | 2013 May 13 |
Optical-resolution photoacoustic microscopy: auscultation of biological systems at the cellular level. | Hu S, Wang LV | Biophysical journal | 23972836 | Biophys J | 2013 Aug 20 |
Sensitivity of photoacoustic microscopy. | Yao J, Wang LV | Photoacoustics | 25302158 | Photoacoustics | 2014 Jun |
High-speed label-free functional photoacoustic microscopy of mouse brain in action. | Yao J, Wang L, Yang JM, Maslov KI, Wong TT, Li L, Huang CH, Zou J, Wang LV | Nature methods | 25822799 | Nat Methods | 2015 May |
Three-dimensional photoacoustic endoscopic imaging of the rabbit esophagus. | Yang JM, Favazza C, Yao J, Chen R, Zhou Q, Shung KK, Wang LV | PloS one | 25874640 | PLoS One | 2015 |
Optical sectioning by wide-field photobleaching imprinting microscopy. | Li C, Gao L, Liu Y, Wang LV | Applied physics letters | 24273331 | Appl Phys Lett | 2013 Oct 28 |
Improving limited-view photoacoustic tomography with an acoustic reflector. | Huang B, Xia J, Maslov K, Wang LV | Journal of biomedical optics | 24285421 | J Biomed Opt | 2013 Nov |
Photoacoustic microscopy: superdepth, superresolution, and superb contrast. | Yao J, Song L, Wang LV | IEEE pulse | 25974913 | IEEE Pulse | 2015 May-Jun |
Reflection-mode multifocal optical-resolution photoacoustic microscopy. | Li G, Maslov KI, Wang LV | Journal of biomedical optics | 23446704 | J Biomed Opt | 2013 Mar |
Label-free photoacoustic nanoscopy. | Danielli A, Maslov K, Garcia-Uribe A, Winkler AM, Li C, Wang L, Chen Y, Dorn GW 2nd, Wang LV | Journal of biomedical optics | 25104412 | J Biomed Opt | 2014 Aug |
High-resolution photoacoustic tomography of resting-state functional connectivity in the mouse brain. | Nasiriavanaki M, Xia J, Wan H, Bauer AQ, Culver JP, Wang LV | Proceedings of the National Academy of Sciences of the United States of America | 24367107 | Proc Natl Acad Sci U S A | 2014 Jan 7 |
Photoacoustic Brain Imaging: from Microscopic to Macroscopic Scales. | Yao J, Wang LV | Neurophotonics | 25401121 | Neurophotonics | 2014 May 28 |
Reversibly switchable fluorescence microscopy with enhanced resolution and image contrast. | Yao J, Shcherbakova DM, Li C, Krumholz A, Lorca RA, Reinl E, England SK, Verkhusha VV, Wang LV | Journal of biomedical optics | 25144452 | J Biomed Opt | 2014 Aug |
Photoimprint photoacoustic microscopy for three-dimensional label-free subdiffraction imaging. | Yao J, Wang L, Li C, Zhang C, Wang LV | Physical review letters | 24483902 | Phys Rev Lett | 2014 Jan 10 |
Dependence of optical scattering from Intralipid in gelatin-gel based tissue-mimicking phantoms on mixing temperature and time. | Lai P, Xu X, Wang LV | Journal of biomedical optics | 24604534 | J Biomed Opt | 2014 Mar |
Focusing light through scattering media by full-polarization digital optical phase conjugation. | Shen Y, Liu Y, Ma C, Wang LV | Optics letters | 26977651 | Opt Lett | 2016 Mar 15 |
Bit-efficient, sub-millisecond wavefront measurement using a lock-in camera for time-reversal based optical focusing inside scattering media. | Liu Y, Ma C, Shen Y, Wang LV | Optics letters | 27192226 | Opt Lett | 2016 Apr 1 |
Bessel-beam Grueneisen relaxation photoacoustic microscopy with extended depth of field. | Shi J, Wang L, Noordam C, Wang LV | Journal of biomedical optics | 26524679 | J Biomed Opt | 2015 Nov |
Multiscale photoacoustic tomography using reversibly switchable bacterial phytochrome as a near-infrared photochromic probe. | Yao J, Kaberniuk AA, Li L, Shcherbakova DM, Zhang R, Wang L, Li G, Verkhusha VV, Wang LV | Nature methods | 26550774 | Nat Methods | 2016 Jan |
Lock-in camera based heterodyne holography for ultrasound-modulated optical tomography inside dynamic scattering media. | Liu Y, Shen Y, Ma C, Shi J, Wang LV | Applied physics letters | 27493275 | Appl Phys Lett | 2016 Jun 6 |
Time-reversed ultrasonically encoded optical focusing through highly scattering ex vivo human cataractous lenses. | Liu Y, Shen Y, Ruan H, Brodie FL, Wong TTW, Yang C, Wang LV | Journal of biomedical optics | 29322749 | J Biomed Opt | 2018 Jan |
Single-impulse Panoramic Photoacoustic Computed Tomography of Small-animal Whole-body Dynamics at High Spatiotemporal Resolution. | Li L, Zhu L, Ma C, Lin L, Yao J, Wang L, Maslov K, Zhang R, Chen W, Shi J, Wang LV | Nature biomedical engineering | 29333331 | Nat Biomed Eng | 2017 |
Label-free cell nuclear imaging by Grüneisen relaxation photoacoustic microscopy. | Liu X, Wong TTW, Shi J, Ma J, Yang Q, Wang LV | Optics letters | 29444034 | Opt Lett | 2018 Feb 15 |
Dichroism-sensitive photoacoustic computed tomography. | Qu Y, Li L, Shen Y, Wei X, Wong TTW, Hu P, Yao J, Maslov K, Wang LV | Optica | 30820444 | Optica | 2018 Apr 20 |
Single-shot real-time femtosecond imaging of temporal focusing. | Liang J, Zhu L, Wang LV | Light, science & applications | 30839588 | Light Sci Appl | 2018 |
In vivo label-free photoacoustic flow cytography and on-the-spot laser killing of single circulating melanoma cells. | He Y, Wang L, Shi J, Yao J, Li L, Zhang R, Huang CH, Zou J, Wang LV | Scientific reports | 28000788 | Sci Rep | 2016 Dec 21 |
Noninvasive Determination of Melanoma Depth using a Handheld Photoacoustic Probe. | Zhou Y, Tripathi SV, Rosman I, Ma J, Hai P, Linette GP, Council ML, Fields RC, Wang LV, Cornelius LA | The Journal of investigative dermatology | 28163070 | J Invest Dermatol | 2017 Jun |
In vivo photoacoustic tomography of myoglobin oxygen saturation. | Lin L, Yao J, Li L, Wang LV | Journal of biomedical optics | 26719943 | J Biomed Opt | 2016 Jun |
Dry coupling for whole-body small-animal photoacoustic computed tomography. | Yeh C, Li L, Zhu L, Xia J, Li C, Chen W, Garcia-Uribe A, Maslov KI, Wang LV | Journal of biomedical optics | 28241305 | J Biomed Opt | 2017 Apr 1 |
Multiview Hilbert transformation in full-ring transducer array-based photoacoustic computed tomography. | Li L, Zhu L, Shen Y, Wang LV | Journal of biomedical optics | 28745385 | J Biomed Opt | 2017 Jul 1 |
Use of a single xenon flash lamp for photoacoustic computed tomography of multiple-centimeter-thick biological tissue ex vivo and a whole mouse body in vivo. | Wong TT, Zhou Y, Garcia-Uribe A, Li L, Maslov K, Lin L, Wang LV | Journal of biomedical optics | 27775747 | J Biomed Opt | 2017 Apr 1 |
In vivo superresolution photoacoustic computed tomography by localization of single dyed droplets. | Zhang P, Li L, Lin L, Shi J, Wang LV | Light, science & applications | 30962922 | Light Sci Appl | 2019 |
Focusing light through biological tissue and tissue-mimicking phantoms up to 9.6 cm in thickness with digital optical phase conjugation. | Shen Y, Liu Y, Ma C, Wang LV | Journal of biomedical optics | 27533439 | J Biomed Opt | 2016 Aug 1 |
High-speed single-shot optical focusing through dynamic scattering media with full-phase wavefront shaping. | Hemphill AS, Shen Y, Liu Y, Wang LV | Applied physics letters | 29249832 | Appl Phys Lett | 2017 Nov 27 |
Focusing light inside live tissue using reversibly switchable bacterial phytochrome as a genetically encoded photochromic guide star. | Yang J, Li L, Shemetov AA, Lee S, Zhao Y, Liu Y, Shen Y, Li J, Oka Y, Verkhusha VV, Wang LV | Science advances | 31844671 | Sci Adv | 2019 Dec |
Micromachined Silicon Parallel Acoustic Delay Lines as Time Delayed Ultrasound Detector Array for Real-Time Photoacoustic Tomography. | Cho Y, Chang CC, Wang LV, Zou J | Journal of optics (2010) | 31998470 | J Opt | 2016 |
A microrobotic system guided by photoacoustic computed tomography for targeted navigation in intestines in vivo. | Wu Z, Li L, Yang Y, Hu P, Li Y, Yang SY, Wang LV, Gao W | Science robotics | 32632399 | Sci Robot | 2019 Jul 31 |
Real-time observation and control of optical chaos. | Fan L, Yan X, Wang H, Wang LV | Science advances | 33523874 | Sci Adv | 2021 Jan |
Calibration-free quantification of absolute oxygen saturation based on the dynamics of photoacoustic signals. | Xia J, Danielli A, Liu Y, Wang L, Maslov K, Wang LV | Optics letters | 23903146 | Opt Lett | 2013 Aug 1 |
Enhancement of photoacoustic tomography by ultrasonic computed tomography based on optical excitation of elements of a full-ring transducer array. | Xia J, Huang C, Maslov K, Anastasio MA, Wang LV | Optics letters | 24104670 | Opt Lett | 2013 Aug 15 |
Small-animal whole-body photoacoustic tomography: a review. | Xia J, Wang LV | IEEE transactions on bio-medical engineering | 24108456 | IEEE Trans Biomed Eng | 2014 May |
Multiscale Functional and Molecular Photoacoustic Tomography. | Yao J, Xia J, Wang LV | Ultrasonic imaging | 25933617 | Ultrason Imaging | 2016 Jan |
A review of snapshot multidimensional optical imaging: measuring photon tags in parallel. | Gao L, Wang LV | Physics reports | 27134340 | Phys Rep | 2016 Feb 29 |
Nonlinear light-sheet fluorescence microscopy by photobleaching imprinting. | Gao L, Zhu L, Li C, Wang LV | Journal of the Royal Society, Interface | 24478278 | J R Soc Interface | 2014 Apr 6 |
Photoacoustic thermography of tissue. | Ke H, Tai S, Wang LV | Journal of biomedical optics | 24522803 | J Biomed Opt | 2014 Feb |
Photoacoustic microscopy and computed tomography: from bench to bedside. | Wang LV, Gao L | Annual review of biomedical engineering | 24905877 | Annu Rev Biomed Eng | 2014 Jul 11 |
Microcirculatory changes identified by photoacoustic microscopy in patients with complex regional pain syndrome type I after stellate ganglion blocks. | Zhou Y, Yi X, Xing W, Hu S, Maslov KI, Wang LV | Journal of biomedical optics | 25144451 | J Biomed Opt | 2014 Aug |
Grueneisen relaxation photoacoustic microscopy. | Wang L, Zhang C, Wang LV | Physical review letters | 25379919 | Phys Rev Lett | 2014 Oct 24 |
Photoacoustic lymphatic imaging with high spatial-temporal resolution. | Martel C, Yao J, Huang CH, Zou J, Randolph GJ, Wang LV | Journal of biomedical optics | 25408958 | J Biomed Opt | 2014 Nov |
Multi-view optical resolution photoacoustic microscopy. | Zhu L, Li L, Gao L, Wang LV | Optica | 25558469 | Optica | 2014 |
Absolute photoacoustic thermometry in deep tissue. | Yao J, Ke H, Tai S, Zhou Y, Wang LV | Optics letters | 24322224 | Opt Lett | 2013 Dec 15 |
Tripling the detection view of high-frequency linear-array-based photoacoustic computed tomography by using two planar acoustic reflectors. | Li G, Xia J, Wang K, Maslov K, Anastasio MA, Wang LV | Quantitative imaging in medicine and surgery | 25694954 | Quant Imaging Med Surg | 2015 Feb |
In vivo photoacoustic microscopy of human cuticle microvasculature with single-cell resolution. | Hsu HC, Wang L, Wang LV | Journal of biomedical optics | 27207113 | J Biomed Opt | 2016 May 1 |
Dual-view photoacoustic microscopy for quantitative cell nuclear imaging. | Cai D, Wong TTW, Zhu L, Shi J, Chen SL, Wang LV | Optics letters | 30320772 | Opt Lett | 2018 Oct 15 |
In vivo characterization of connective tissue remodeling using infrared photoacoustic spectra. | Qu Y, Hu P, Shi J, Maslov K, Zhao P, Li C, Ma J, Garcia-Uribe A, Meyers K, Diveley E, Pizzella S, Muench L, Punyamurthy N, Goldstein N, Onwumere O, Alisio M, Meyenburg K, Maynard J, Helm K, Altieri E, Slaughter J, Barber S, Burger T, Kramer C, Chubiz J, Anderson M, McCarthy R, England SK, Macones GA, Stout MJ, Tuuli M, Wang LV | Journal of biomedical optics | 30520275 | J Biomed Opt | 2018 Dec |
Single-breath-hold photoacoustic computed tomography of the breast. | Lin L, Hu P, Shi J, Appleton CM, Maslov K, Li L, Zhang R, Wang LV | Nature communications | 29907740 | Nat Commun | 2018 Jun 15 |
Label-free photoacoustic tomography of whole mouse brain structures ex vivo. | Li L, Xia J, Li G, Garcia-Uribe A, Sheng Q, Anastasio MA, Wang LV | Neurophotonics | 29181425 | Neurophotonics | 2016 Jul |
Nonlinear photoacoustic spectroscopy of hemoglobin. | Danielli A, Maslov K, Favazza CP, Xia J, Wang LV | Applied physics letters | 26045627 | Appl Phys Lett | 2015 May 18 |
Ultrasonically encoded photoacoustic flowgraphy in biological tissue. | Wang L, Xia J, Yao J, Maslov KI, Wang LV | Physical review letters | 24289689 | Phys Rev Lett | 2013 Nov 15 |
Graphene-based contrast agents for photoacoustic and thermoacoustic tomography. | Lalwani G, Cai X, Nie L, Wang LV, Sitharaman B | Photoacoustics | 24490141 | Photoacoustics | 2013 Dec 1 |
Label-free photoacoustic microscopy of peripheral nerves. | Matthews TP, Zhang C, Yao DK, Maslov K, Wang LV | Journal of biomedical optics | 24395587 | J Biomed Opt | 2014 Jan |
Calibration-free structured-illumination photoacoustic flowgraphy of transverse flow in scattering media. | Yao J, Gilson RC, Maslov KI, Wang L, Wang LV | Journal of biomedical optics | 24718385 | J Biomed Opt | 2014 Apr |
Microvascular quantification based on contour-scanning photoacoustic microscopy. | Yeh C, Soetikno B, Hu S, Maslov KI, Wang LV | Journal of biomedical optics | 25223708 | J Biomed Opt | 2014 Sep |
Space- and intensity-constrained reconstruction for compressed ultrafast photography. | Zhu L, Chen Y, Liang J, Xu Q, Gao L, Ma C, Wang LV | Optica | 28775997 | Optica | 2016 Jul |
Motionless volumetric photoacoustic microscopy with spatially invariant resolution. | Yang J, Gong L, Xu X, Hai P, Shen Y, Suzuki Y, Wang LV | Nature communications | 28974681 | Nat Commun | 2017 Oct 3 |
A practical guide to photoacoustic tomography in the life sciences. | Wang LV, Yao J | Nature methods | 27467726 | Nat Methods | 2016 Jul 28 |
Analog time-reversed ultrasonically encoded light focusing inside scattering media with a 33,000× optical power gain. | Ma C, Xu X, Wang LV | Scientific reports | 25753905 | Sci Rep | 2015 Mar 10 |
Noninvasive photoacoustic microscopy of methemoglobin in vivo. | Tang M, Zhou Y, Zhang R, Wang LV | Journal of biomedical optics | 25760655 | J Biomed Opt | 2015 Mar |
Single-shot photoacoustic imaging with single-element transducer through a spatiotemporal encoder. | Zhao Y, Wang LV | Journal of biomedical optics | 37065647 | J Biomed Opt | 2023 Apr |
Photoacoustic and optical coherence tomography of epilepsy with high temporal and spatial resolution and dual optical contrasts. | Tsytsarev V, Rao B, Maslov KI, Li L, Wang LV | Journal of neuroscience methods | 23603664 | J Neurosci Methods | 2013 Jun 15 |
Snapshot Photoacoustic Topography Through an Ergodic Relay for High-throughput Imaging of Optical Absorption. | Li Y, Li L, Zhu L, Maslov K, Shi J, Hu P, Bo E, Yao J, Liang J, Wang L, Wang LV | Nature photonics | 34178097 | Nat Photonics | 2020 Mar |
The distinct roles of calcium in rapid control of neuronal glycolysis and the tricarboxylic acid cycle. | Díaz-García CM, Meyer DJ, Nathwani N, Rahman M, Martínez-François JR, Yellen G | eLife | 33555254 | Elife | 2021 Feb 8 |
Integration of Multitargeted Polymer-Based Contrast Agents with Photoacoustic Computed Tomography: An Imaging Technique to Visualize Breast Cancer Intratumor Heterogeneity. | Li L, Patil D, Petruncio G, Harnden KK, Somasekharan JV, Paige M, Wang LV, Salvador-Morales C | ACS nano | 33464827 | ACS Nano | 2021 Feb 23 |
Breakthrough in Photonics 2013: Photoacoustic Tomography in Biomedicine. | Yao J, Wang LV | IEEE photonics journal | 25383143 | IEEE Photonics J | 2014 Apr |
Frequency-swept time-reversed ultrasonically encoded optical focusing. | Suzuki Y, Wang LV | Applied physics letters | 25425744 | Appl Phys Lett | 2014 Nov 10 |
Near-infrared optical-resolution photoacoustic microscopy. | Hai P, Yao J, Maslov KI, Zhou Y, Wang LV | Optics letters | 25166107 | Opt Lett | 2014 Sep 1 |
Handheld photoacoustic microscopy to detect melanoma depth in vivo. | Zhou Y, Xing W, Maslov KI, Cornelius LA, Wang LV | Optics letters | 25121860 | Opt Lett | 2014 Aug 15 |
Structured-illumination photoacoustic Doppler flowmetry of axial flow in homogeneous scattering media. | Zhang R, Yao J, Maslov KI, Wang LV | Applied physics letters | 24065864 | Appl Phys Lett | 2013 Aug 26 |
Cross-correlation-based transverse flow measurements using optical resolution photoacoustic microscopy with a digital micromirror device. | Liang J, Zhou Y, Maslov KI, Wang LV | Journal of biomedical optics | 24002191 | J Biomed Opt | 2013 Sep |
In vivo deep brain imaging of rats using oral-cavity illuminated photoacoustic computed tomography. | Lin L, Xia J, Wong TT, Li L, Wang LV | Journal of biomedical optics | 25611865 | J Biomed Opt | 2015 Jan |
High-throughput, label-free, single-cell photoacoustic microscopy of intratumoral metabolic heterogeneity. | Hai P, Imai T, Xu S, Zhang R, Aft RL, Zou J, Wang LV | Nature biomedical engineering | 30936431 | Nat Biomed Eng | 2019 May |
Real-time frequency-encoded spatiotemporal focusing through scattering media using a programmable 2D ultrafine optical frequency comb. | Wei X, Shen Y, Jing JC, Hemphill AS, Yang C, Xu S, Yang Z, Wang LV | Science advances | 32128401 | Sci Adv | 2020 Feb |
Label-free automated three-dimensional imaging of whole organs by microtomy-assisted photoacoustic microscopy. | Wong TTW, Zhang R, Zhang C, Hsu HC, Maslov KI, Wang L, Shi J, Chen R, Shung KK, Zhou Q, Wang LV | Nature communications | 29123109 | Nat Commun | 2017 Nov 9 |
Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo. | Li L, Shemetov AA, Baloban M, Hu P, Zhu L, Shcherbakova DM, Zhang R, Shi J, Yao J, Wang LV, Verkhusha VV | Nature communications | 30013153 | Nat Commun | 2018 Jul 16 |
Single-exposure optical focusing inside scattering media using binarized time-reversed adapted perturbation. | Ma C, Zhou F, Liu Y, Wang LV | Optica | 30221184 | Optica | 2015 Oct |
Recent progress in photoacoustic molecular imaging. | Yao J, Wang LV | Current opinion in chemical biology | 29631120 | Curr Opin Chem Biol | 2018 Aug |
Synthetic Bessel light needle for extended depth-of-field microscopy. | Yang J, Gong L, Shen Y, Wang LV | Applied physics letters | 30449893 | Appl Phys Lett | 2018 Oct 29 |
Label-free high-throughput photoacoustic tomography of suspected circulating melanoma tumor cells in patients in vivo. | Hai P, Qu Y, Li Y, Zhu L, Shmuylovich L, Cornelius LA, Wang LV | Journal of biomedical optics | 32170857 | J Biomed Opt | 2020 Mar |
Ultrasonically encoded wavefront shaping for focusing into random media. | Tay JW, Lai P, Suzuki Y, Wang LV | Scientific reports | 24472822 | Sci Rep | 2014 Jan 29 |
Photobleaching imprinting microscopy: seeing clearer and deeper. | Gao L, Garcia-Uribe A, Liu Y, Li C, Wang LV | Journal of cell science | 24317295 | J Cell Sci | 2014 Jan 15 |
Catheter-based photoacoustic endoscope. | Yang JM, Li C, Chen R, Zhou Q, Shung KK, Wang LV | Journal of biomedical optics | 24887743 | J Biomed Opt | 2014 Jun |
alphaVbeta3-targeted copper nanoparticles incorporating an Sn 2 lipase-labile fumagillin prodrug for photoacoustic neovascular imaging and treatment. | Zhang R, Pan D, Cai X, Yang X, Senpan A, Allen JS, Lanza GM, Wang LV | Theranostics | 25553103 | Theranostics | 2015 |
Optical focusing deep inside dynamic scattering media with near-infrared time-reversed ultrasonically encoded (TRUE) light. | Liu Y, Lai P, Ma C, Xu X, Grabar AA, Wang LV | Nature communications | 25556918 | Nat Commun | 2015 Jan 5 |
Time-reversed adapted-perturbation (TRAP) optical focusing onto dynamic objects inside scattering media. | Ma C, Xu X, Liu Y, Wang LV | Nature photonics | 25530797 | Nat Photonics | 2014 Dec |
Handheld photoacoustic probe to detect both melanoma depth and volume at high speed in vivo. | Zhou Y, Li G, Zhu L, Li C, Cornelius LA, Wang LV | Journal of biophotonics | 25676898 | J Biophotonics | 2015 Nov |
Focused fluorescence excitation with time-reversed ultrasonically encoded light and imaging in thick scattering media. | Lai P, Suzuki Y, Xu X, Wang LV | Laser physics letters | 24465244 | Laser Phys Lett | 2013 |
Fully motorized optical-resolution photoacoustic microscopy. | Li L, Yeh C, Hu S, Wang L, Soetikno BT, Chen R, Zhou Q, Shung KK, Maslov KI, Wang LV | Optics letters | 24686689 | Opt Lett | 2014 Apr 1 |
Integrated photoacoustic, confocal, and two-photon microscope. | Rao B, Soto F, Kerschensteiner D, Wang LV | Journal of biomedical optics | 24589986 | J Biomed Opt | 2014 Mar |
Plasmonics-enhanced and optically modulated delivery of gold nanostars into brain tumor. | Yuan H, Wilson CM, Xia J, Doyle SL, Li S, Fales AM, Liu Y, Ozaki E, Mulfaul K, Hanna G, Palmer GM, Wang LV, Grant GA, Vo-Dinh T | Nanoscale | 24619405 | Nanoscale | 2014 Apr 21 |
Amplitude-masked photoacoustic wavefront shaping and application in flowmetry. | Tay JW, Liang J, Wang LV | Optics letters | 25360912 | Opt Lett | 2014 Oct 1 |
Noise-equivalent sensitivity of photoacoustics. | Winkler AM, Maslov K, Wang LV | Journal of biomedical optics | 24026425 | J Biomed Opt | 2013 Sep |
Photoacoustic tomography of vascular compliance in humans. | Hai P, Zhou Y, Liang J, Li C, Wang LV | Journal of biomedical optics | 26720875 | J Biomed Opt | 2015 |
Photoacoustic elastography. | Hai P, Yao J, Li G, Li C, Wang LV | Optics letters | 26872173 | Opt Lett | 2016 Feb 15 |
Grueneisen relaxation photoacoustic microscopy in vivo. | Ma J, Shi J, Hai P, Zhou Y, Wang LV | Journal of biomedical optics | 27272096 | J Biomed Opt | 2016 Jun 1 |
Quantitative photoacoustic elastography in humans. | Hai P, Zhou Y, Gong L, Wang LV | Journal of biomedical optics | 27304419 | J Biomed Opt | 2016 Jun 1 |
Tutorial on photoacoustic tomography. | Zhou Y, Yao J, Wang LV | Journal of biomedical optics | 27086868 | J Biomed Opt | 2016 Jun |
Photoacoustic microscopy of arteriovenous shunts and blood diffusion in early-stage tumors. | Yeh C, Liang J, Zhou Y, Hu S, Sohn RE, Arbeit JM, Wang LV | Journal of biomedical optics | 26882446 | J Biomed Opt | 2016 Feb |
Hybridized wavefront shaping for high-speed, high-efficiency focusing through dynamic diffusive media. | Hemphill AS, Tay JW, Wang LV | Journal of biomedical optics | 27626770 | J Biomed Opt | 2016 Dec 1 |
Fast label-free multilayered histology-like imaging of human breast cancer by photoacoustic microscopy. | Wong TTW, Zhang R, Hai P, Zhang C, Pleitez MA, Aft RL, Novack DV, Wang LV | Science advances | 28560329 | Sci Adv | 2017 May |
High-resolution deep functional imaging of the whole mouse brain by photoacoustic computed tomography in vivo. | Zhang P, Li L, Lin L, Hu P, Shi J, He Y, Zhu L, Zhou Y, Wang LV | Journal of biophotonics | 28635056 | J Biophotonics | 2018 Jan |
A PKA activity sensor for quantitative analysis of endogenous GPCR signaling via 2-photon FRET-FLIM imaging. | Chen Y, Saulnier JL, Yellen G, Sabatini BL | Frontiers in pharmacology | 24765076 | Front Pharmacol | 2014 |
Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step. | Shestov AA, Liu X, Ser Z, Cluntun AA, Hung YP, Huang L, Kim D, Le A, Yellen G, Albeck JG, Locasale JW | eLife | 25009227 | Elife | 2014 Jul 9 |
Quantitative two-photon imaging of fluorescent biosensors. | Yellen G, Mongeon R | Current opinion in chemical biology | 26079046 | Curr Opin Chem Biol | 2015 Aug |
BAD and K(ATP) channels regulate neuron excitability and epileptiform activity. | Martínez-François JR, Fernández-Agüera MC, Nathwani N, Lahmann C, Burnham VL, Danial NN, Yellen G | eLife | 29368690 | Elife | 2018 Jan 25 |
Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells. | Hung YP, Teragawa C, Kosaisawe N, Gillies TE, Pargett M, Minguet M, Distor K, Rocha-Gregg BL, Coloff JL, Keibler MA, Stephanopoulos G, Yellen G, Brugge JS, Albeck JG | eLife | 29239720 | Elife | 2017 Dec 14 |
Live-cell imaging of cytosolic NADH-NAD+ redox state using a genetically encoded fluorescent biosensor. | Hung YP, Yellen G | Methods in molecular biology (Clifton, N.J.) | 24052382 | Methods Mol Biol | 2014 |
Imaging changes in the cytosolic ATP-to-ADP ratio. | Tantama M, Yellen G | Methods in enzymology | 25416365 | Methods Enzymol | 2014 |
Quantitative in vivo imaging of neuronal glucose concentrations with a genetically encoded fluorescence lifetime sensor. | Díaz-García CM, Lahmann C, Martínez-François JR, Li B, Koveal D, Nathwani N, Rahman M, Keller JP, Marvin JS, Looger LL, Yellen G | Journal of neuroscience research | 31106909 | J Neurosci Res | 2019 Aug |
Hepatic NADH reductive stress underlies common variation in metabolic traits. | Goodman RP, Markhard AL, Shah H, Sharma R, Skinner OS, Clish CB, Deik A, Patgiri A, Hsu YH, Masia R, Noh HL, Suk S, Goldberger O, Hirschhorn JN, Yellen G, Kim JK, Mootha VK | Nature | 32461692 | Nature | 2020 Jul |
BAD knockout provides metabolic seizure resistance in a genetic model of epilepsy with sudden unexplained death in epilepsy. | Foley J, Burnham V, Tedoldi M, Danial NN, Yellen G | Epilepsia | 29171006 | Epilepsia | 2018 Jan |
Live cell imaging of cytosolic NADH/NAD(+) ratio in hepatocytes and liver slices. | Masia R, McCarty WJ, Lahmann C, Luther J, Chung RT, Yarmush ML, Yellen G | American journal of physiology. Gastrointestinal and liver physiology | 29025729 | Am J Physiol Gastrointest Liver Physiol | 2018 Jan 1 |
Imaging energy status in live cells with a fluorescent biosensor of the intracellular ATP-to-ADP ratio. | Tantama M, Martínez-François JR, Mongeon R, Yellen G | Nature communications | 24096541 | Nat Commun | 2013 |
Fueling thought: Management of glycolysis and oxidative phosphorylation in neuronal metabolism. | Yellen G | The Journal of cell biology | 29752396 | J Cell Biol | 2018 Jul 2 |
Neuronal Stimulation Triggers Neuronal Glycolysis and Not Lactate Uptake. | Díaz-García CM, Mongeon R, Lahmann C, Koveal D, Zucker H, Yellen G | Cell metabolism | 28768175 | Cell Metab | 2017 Aug 1 |
The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons. | Lutas A, Lahmann C, Soumillon M, Yellen G | eLife | 27177420 | Elife | 2016 May 13 |
Cytosolic NADH-NAD(+) Redox Visualized in Brain Slices by Two-Photon Fluorescence Lifetime Biosensor Imaging. | Mongeon R, Venkatachalam V, Yellen G | Antioxidants & redox signaling | 26857245 | Antioxid Redox Signal | 2016 Oct 1 |
Live Births from Domestic Dog (Canis familiaris) Embryos Produced by In Vitro Fertilization. | Nagashima JB, Sylvester SR, Nelson JL, Cheong SH, Mukai C, Lambo C, Flanders JA, Meyers-Wallen VN, Songsasen N, Travis AJ | PloS one | 26650234 | PLoS One | 2015 |
The role of MATER in endoplasmic reticulum distribution and calcium homeostasis in mouse oocytes. | Kim B, Zhang X, Kan R, Cohen R, Mukai C, Travis AJ, Coonrod SA | Developmental biology | 24374158 | Dev Biol | 2014 Feb 15 |
Biomimicry enhances sequential reactions of tethered glycolytic enzymes, TPI and GAPDHS. | Mukai C, Gao L, Bergkvist M, Nelson JL, Hinchman MM, Travis AJ | PloS one | 23626684 | PLoS One | 2013 |
Pretreatment of Asian elephant (Elephas maximus) spermatozoa with cholesterol-loaded cyclodextrins and glycerol addition at 4°C improves cryosurvival. | Kiso WK, Asano A, Travis AJ, Schmitt DL, Brown JL, Pukazhenthi BS | Reproduction, fertility, and development | 22954260 | Reprod Fertil Dev | 2012 |
Ferromagnetic nanoparticles with peroxidase-like activity enhance the cleavage of biological macromolecules for biofilm elimination. | Gao L, Giglio KM, Nelson JL, Sondermann H, Travis AJ | Nanoscale | 24468900 | Nanoscale | 2014 Mar 7 |
Biomimicry Promotes the Efficiency of a 10-Step Sequential Enzymatic Reaction on Nanoparticles, Converting Glucose to Lactate. | Mukai C, Gao L, Nelson JL, Lata JP, Cohen R, Wu L, Hinchman MM, Bergkvist M, Sherwood RW, Zhang S, Travis AJ | Angewandte Chemie (International ed. in English) | 27901298 | Angew Chem Int Ed Engl | 2017 Jan 2 |
Tunable loading of oligonucleotides with secondary structure on gold nanoparticles through a pH-driven method. | Dam DH, Lee H, Lee RC, Kim KH, Kelleher NL, Odom TW | Bioconjugate chemistry | 25564799 | Bioconjug Chem | 2015 Feb 18 |
Subwavelength lattice optics by evolutionary design. | Huntington MD, Lauhon LJ, Odom TW | Nano letters | 25380062 | Nano Lett | 2014 Dec 10 |
Enhanced Human Epidermal Growth Factor Receptor 2 Degradation in Breast Cancer Cells by Lysosome-Targeting Gold Nanoconstructs. | Lee H, Dam DH, Ha JW, Yue J, Odom TW | ACS nano | 26335372 | ACS Nano | 2015 Oct 27 |
Fingerprint Stimulated Raman Scattering Imaging Reveals Retinoid Coupling Lipid Metabolism and Survival. | Chen AJ, Li J, Jannasch A, Mutlu AS, Wang MC, Cheng JX | Chemphyschem : a European journal of chemical physics and physical chemistry | 29911339 | Chemphyschem | 2018 Oct 5 |
'Inside Out'- a dialogue between mitochondria and bacteria. | Han B, Lin CJ, Hu G, Wang MC | The FEBS journal | 30390412 | FEBS J | 2019 Feb |
Targeting calcium-mediated inter-organellar crosstalk in cardiac diseases. | Hulsurkar MM, Lahiri SK, Karch J, Wang MC, Wehrens XHT | Expert opinion on therapeutic targets | 35426759 | Expert Opin Ther Targets | 2022 Apr |
Microbial metabolites regulate host lipid metabolism through NR5A-Hedgehog signalling. | Lin CJ, Wang MC | Nature cell biology | 28436966 | Nat Cell Biol | 2017 May |
Localized glucose import, glycolytic processing, and mitochondria generate a focused ATP burst to power basement-membrane invasion. | Garde A, Kenny IW, Kelley LC, Chi Q, Mutlu AS, Wang MC, Sherwood DR | Developmental cell | 35316617 | Dev Cell | 2022 Mar 28 |
Structural characterization of life-extending Caenorhabditis elegans Lipid Binding Protein 8. | Tillman MC, Khadka M, Duffy J, Wang MC, Ortlund EA | Scientific reports | 31292465 | Sci Rep | 2019 Jul 10 |
Lysosomal Signaling Promotes Longevity by Adjusting Mitochondrial Activity. | Ramachandran PV, Savini M, Folick AK, Hu K, Masand R, Graham BH, Wang MC | Developmental cell | 30713071 | Dev Cell | 2019 Mar 11 |
Aging: Antagonistic Pleiotropy Supported by Gut Eating. | Park M, Wang MC | Current biology : CB | 30130513 | Curr Biol | 2018 Aug 20 |
Reversible Reaction-Based Fluorescent Probe for Real-Time Imaging of Glutathione Dynamics in Mitochondria. | Chen J, Jiang X, Zhang C, MacKenzie KR, Stossi F, Palzkill T, Wang MC, Wang J | ACS sensors | 28809477 | ACS Sens | 2017 Sep 22 |
Quantitative Real-Time Imaging of Glutathione with Subcellular Resolution. | Jiang X, Zhang C, Chen J, Choi S, Zhou Y, Zhao M, Song X, Chen X, Maletić-Savatić M, Palzkill T, Moore D, Wang MC, Wang J | Antioxidants & redox signaling | 30358421 | Antioxid Redox Signal | 2019 Jun 1 |
Does Autophagy Promote Longevity? It Depends. | Savini M, Wang MC | Cell | 30951663 | Cell | 2019 Apr 4 |
Building multidisciplinary research. | Wang MC | Molecular biology of the cell | 29084905 | Mol Biol Cell | 2017 Nov 1 |
High-throughput screens using photo-highlighting discover BMP signaling in mitochondrial lipid oxidation. | Yu Y, Mutlu AS, Liu H, Wang MC | Nature communications | 29021566 | Nat Commun | 2017 Oct 11 |
Dissecting lipid droplet biology with coherent Raman scattering microscopy. | Chen T, Yavuz A, Wang MC | Journal of cell science | 33975358 | J Cell Sci | 2022 Mar 1 |
Host and microbiota metabolic signals in aging and longevity. | Zhou Y, Hu G, Wang MC | Nature chemical biology | 34552221 | Nat Chem Biol | 2021 Oct |
Optogenetic control of gut bacterial metabolism to promote longevity. | Hartsough LA, Park M, Kotlajich MV, Lazar JT, Han B, Lin CJ, Musteata E, Gambill L, Wang MC, Tabor JJ | eLife | 33325823 | Elife | 2020 Dec 16 |
Mitochondrial GTP metabolism controls reproductive aging in C. elegans. | Lee YT, Savini M, Chen T, Yang J, Zhao Q, Ding L, Gao SM, Senturk M, Sowa JN, Wang JD, Wang MC | Developmental cell | 37708895 | Dev Cell | 2023 Dec 4 |
Molecular Mechanisms of Lysosome and Nucleus Communication. | Zhao Q, Gao SM, Wang MC | Trends in biochemical sciences | 32624271 | Trends Biochem Sci | 2020 Nov |
Label-Free Imaging of Lipid Storage Dynamics in Caenorhabditis elegans using Stimulated Raman Scattering Microscopy. | Mutlu AS, Chen T, Deng D, Wang MC | Journal of visualized experiments : JoVE | 34125101 | J Vis Exp | 2021 May 28 |
3D genomics across the tree of life reveals condensin II as a determinant of architecture type. | Hoencamp C, Dudchenko O, Elbatsh AMO, Brahmachari S, Raaijmakers JA, van Schaik T, Sedeño Cacciatore Á, Contessoto VG, van Heesbeen RGHP, van den Broek B, Mhaskar AN, Teunissen H, St Hilaire BG, Weisz D, Omer AD, Pham M, Colaric Z, Yang Z, Rao SSP, Mitra N, Lui C, Yao W, Khan R, Moroz LL, Kohn A, St Leger J, Mena A, Holcroft K, Gambetta MC, Lim F, Farley E, Stein N, Haddad A, Chauss D, Mutlu AS, Wang MC, Young ND, Hildebrandt E, Cheng HH, Knight CJ, Burnham TLU, Hovel KA, Beel AJ, Mattei PJ, Kornberg RD, Warren WC, Cary G, Gómez-Skarmeta JL, Hinman V, Lindblad-Toh K, Di Palma F, Maeshima K, Multani AS, Pathak S, Nel-Themaat L, Behringer RR, Kaur P, Medema RH, van Steensel B, de Wit E, Onuchic JN, Di Pierro M, Lieberman Aiden E, Rowland BD | Science (New York, N.Y.) | 34045355 | Science | 2021 May 28 |
Lipid metabolism and lipid signals in aging and longevity. | Mutlu AS, Duffy J, Wang MC | Developmental cell | 33891896 | Dev Cell | 2021 May 17 |
Quantitative real-time imaging of glutathione. | Jiang X, Chen J, Bajić A, Zhang C, Song X, Carroll SL, Cai ZL, Tang M, Xue M, Cheng N, Schaaf CP, Li F, MacKenzie KR, Ferreon ACM, Xia F, Wang MC, Maletić-Savatić M, Wang J | Nature communications | 28703127 | Nat Commun | 2017 Jul 13 |
Olfactory specificity regulates lipid metabolism through neuroendocrine signaling in Caenorhabditis elegans. | Mutlu AS, Gao SM, Zhang H, Wang MC | Nature communications | 32193370 | Nat Commun | 2020 Mar 19 |
Lysosomes: Signaling Hubs for Metabolic Sensing and Longevity. | Savini M, Zhao Q, Wang MC | Trends in cell biology | 31611045 | Trends Cell Biol | 2019 Nov |
Lipid droplets and peroxisomes are co-regulated to drive lifespan extension in response to mono-unsaturated fatty acids. | Papsdorf K, Miklas JW, Hosseini A, Cabruja M, Morrow CS, Savini M, Yu Y, Silva-García CG, Haseley NR, Murphy LM, Yao P, de Launoit E, Dixon SJ, Snyder MP, Wang MC, Mair WB, Brunet A | Nature cell biology | 37127715 | Nat Cell Biol | 2023 May |
Aging atlas reveals cell-type-specific effects of pro-longevity strategies. | Gao SM, Qi Y, Zhang Q, Guan Y, Lee YT, Ding L, Wang L, Mohammed AS, Li H, Fu Y, Wang MC | Nature aging | 38816550 | Nat Aging | 2024 Jul |
Challenges and Opportunities for Small-Molecule Fluorescent Probes in Redox Biology Applications. | Jiang X, Wang L, Carroll SL, Chen J, Wang MC, Wang J | Antioxidants & redox signaling | 29320869 | Antioxid Redox Signal | 2018 Aug 20 |
The Bacterivore's Solution: Fight and Flight to Promote Survival. | Lee YT, Wang MC | Developmental cell | 30965036 | Dev Cell | 2019 Apr 8 |
Microbial Genetic Composition Tunes Host Longevity. | Han B, Sivaramakrishnan P, Lin CJ, Neve IAA, He J, Tay LWR, Sowa JN, Sizovs A, Du G, Wang J, Herman C, Wang MC | Cell | 28622510 | Cell | 2017 Jun 15 |
Microbial Genetic Composition Tunes Host Longevity. | Han B, Sivaramakrishnan P, Lin CJ, Neve IAA, He J, Tay LWR, Sowa JN, Sizovs A, Du G, Wang J, Herman C, Wang MC | Cell | 29727664 | Cell | 2018 May 3 |
Methyl-Sensing Nuclear Receptor Liver Receptor Homolog-1 Regulates Mitochondrial Function in Mouse Hepatocytes. | Choi S, Dong B, Lin CJ, Heo MJ, Kim KH, Sun Z, Wagner M, Putluri N, Suh JM, Wang MC, Moore DD | Hepatology (Baltimore, Md.) | 31355949 | Hepatology | 2020 Mar |
Escherichia coli Metabolite Profiling Leads to the Development of an RNA Interference Strain for Caenorhabditis elegans. | Neve IAA, Sowa JN, Lin CJ, Sivaramakrishnan P, Herman C, Ye Y, Han L, Wang MC | G3 (Bethesda, Md.) | 31712257 | G3 (Bethesda) | 2020 Jan 7 |
Lysosome lipid signalling from the periphery to neurons regulates longevity. | Savini M, Folick A, Lee YT, Jin F, Cuevas A, Tillman MC, Duffy JD, Zhao Q, Neve IA, Hu PW, Yu Y, Zhang Q, Ye Y, Mair WB, Wang J, Han L, Ortlund EA, Wang MC | Nature cell biology | 35681008 | Nat Cell Biol | 2022 Jun |
Mediterranean mechanisms of longevity. | Mendenhall AR | Nature cell biology | 37127713 | Nat Cell Biol | 2023 May |
Four Key Steps Control Glycolytic Flux in Mammalian Cells. | Tanner LB, Goglia AG, Wei MH, Sehgal T, Parsons LR, Park JO, White E, Toettcher JE, Rabinowitz JD | Cell systems | 29960885 | Cell Syst | 2018 Jul 25 |
Metabolomics and Isotope Tracing. | Jang C, Chen L, Rabinowitz JD | Cell | 29727671 | Cell | 2018 May 3 |
SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia. | García-Cañaveras JC, Lancho O, Ducker GS, Ghergurovich JM, Xu X, da Silva-Diz V, Minuzzo S, Indraccolo S, Kim H, Herranz D, Rabinowitz JD | Leukemia | 32382081 | Leukemia | 2021 Feb |
Glucose-6-Phosphate Dehydrogenase Is Not Essential for K-Ras-Driven Tumor Growth or Metastasis. | Ghergurovich JM, Esposito M, Chen Z, Wang JZ, Bhatt V, Lan T, White E, Kang Y, Guo JY, Rabinowitz JD | Cancer research | 32661137 | Cancer Res | 2020 Sep 15 |
GCN2 adapts protein synthesis to scavenging-dependent growth. | Nofal M, Wang T, Yang L, Jankowski CSR, Hsin-Jung Li S, Han S, Parsons L, Frese AN, Gitai Z, Anthony TG, Wühr M, Sabatini DM, Rabinowitz JD | Cell systems | 34706266 | Cell Syst | 2022 Feb 16 |
The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids. | Jang C, Hui S, Lu W, Cowan AJ, Morscher RJ, Lee G, Liu W, Tesz GJ, Birnbaum MJ, Rabinowitz JD | Cell metabolism | 29414685 | Cell Metab | 2018 Feb 6 |
The metabolites NADP(+) and NADPH are the targets of the circadian protein Nocturnin (Curled). | Estrella MA, Du J, Chen L, Rath S, Prangley E, Chitrakar A, Aoki T, Schedl P, Rabinowitz J, Korennykh A | Nature communications | 31147539 | Nat Commun | 2019 May 30 |
The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine. | Yu D, Richardson NE, Green CL, Spicer AB, Murphy ME, Flores V, Jang C, Kasza I, Nikodemova M, Wakai MH, Tomasiewicz JL, Yang SE, Miller BR, Pak HH, Brinkman JA, Rojas JM, Quinn WJ 3rd, Cheng EP, Konon EN, Haider LR, Finke M, Sonsalla M, Alexander CM, Rabinowitz JD, Baur JA, Malecki KC, Lamming DW | Cell metabolism | 33887198 | Cell Metab | 2021 May 4 |
Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids. | Neinast MD, Jang C, Hui S, Murashige DS, Chu Q, Morscher RJ, Li X, Zhan L, White E, Anthony TG, Rabinowitz JD, Arany Z | Cell metabolism | 30449684 | Cell Metab | 2019 Feb 5 |
Gut bacterial nutrient preferences quantified in vivo. | Zeng X, Xing X, Gupta M, Keber FC, Lopez JG, Lee YJ, Roichman A, Wang L, Neinast MD, Donia MS, Wühr M, Jang C, Rabinowitz JD | Cell | 36055202 | Cell | 2022 Sep 1 |
The pentose phosphate pathway in health and disease. | TeSlaa T, Ralser M, Fan J, Rabinowitz JD | Nature metabolism | 37612403 | Nat Metab | 2023 Aug |
Metabolite Exchange between Mammalian Organs Quantified in Pigs. | Jang C, Hui S, Zeng X, Cowan AJ, Wang L, Chen L, Morscher RJ, Reyes J, Frezza C, Hwang HY, Imai A, Saito Y, Okamoto K, Vaspoli C, Kasprenski L, Zsido GA 2nd, Gorman JH 3rd, Gorman RC, Rabinowitz JD | Cell metabolism | 31257152 | Cell Metab | 2019 Sep 3 |
Extraction and Quantitation of Nicotinamide Adenine Dinucleotide Redox Cofactors. | Lu W, Wang L, Chen L, Hui S, Rabinowitz JD | Antioxidants & redox signaling | 28497978 | Antioxid Redox Signal | 2018 Jan 20 |
Macrophage de novo NAD(+) synthesis specifies immune function in aging and inflammation. | Minhas PS, Liu L, Moon PK, Joshi AU, Dove C, Mhatre S, Contrepois K, Wang Q, Lee BA, Coronado M, Bernstein D, Snyder MP, Migaud M, Majeti R, Mochly-Rosen D, Rabinowitz JD, Andreasson KI | Nature immunology | 30478397 | Nat Immunol | 2019 Jan |
Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain. | McKee SE, Zhang S, Chen L, Rabinowitz JD, Reyes TM | Journal of neurochemistry | 29423909 | J Neurochem | 2018 Jun |
Myeloid-derived itaconate suppresses cytotoxic CD8(+) T cells and promotes tumour growth. | Zhao H, Teng D, Yang L, Xu X, Chen J, Jiang T, Feng AY, Zhang Y, Frederick DT, Gu L, Cai L, Asara JM, Pasca di Magliano M, Boland GM, Flaherty KT, Swanson KD, Liu D, Rabinowitz JD, Zheng B | Nature metabolism | 36376563 | Nat Metab | 2022 Dec |
Serine Metabolism Supports Macrophage IL-1β Production. | Rodriguez AE, Ducker GS, Billingham LK, Martinez CA, Mainolfi N, Suri V, Friedman A, Manfredi MG, Weinberg SE, Rabinowitz JD, Chandel NS | Cell metabolism | 30773464 | Cell Metab | 2019 Apr 2 |
Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8(+) T cell stemness and antitumor immunity. | Hermans D, Gautam S, García-Cañaveras JC, Gromer D, Mitra S, Spolski R, Li P, Christensen S, Nguyen R, Lin JX, Oh J, Du N, Veenbergen S, Fioravanti J, Ebina-Shibuya R, Bleck C, Neckers LM, Rabinowitz JD, Gattinoni L, Leonard WJ | Proceedings of the National Academy of Sciences of the United States of America | 32123114 | Proc Natl Acad Sci U S A | 2020 Mar 17 |
Serine catabolism generates liver NADPH and supports hepatic lipogenesis. | Zhang Z, TeSlaa T, Xu X, Zeng X, Yang L, Xing G, Tesz GJ, Clasquin MF, Rabinowitz JD | Nature metabolism | 34845393 | Nat Metab | 2021 Dec |
Spatially resolved isotope tracing reveals tissue metabolic activity. | Wang L, Xing X, Zeng X, Jackson SR, TeSlaa T, Al-Dalahmah O, Samarah LZ, Goodwin K, Yang L, McReynolds MR, Li X, Wolff JJ, Rabinowitz JD, Davidson SM | Nature methods | 35132243 | Nat Methods | 2022 Feb |
Local production of lactate, ribose phosphate, and amino acids within human triple-negative breast cancer. | Ghergurovich JM, Lang JD, Levin MK, Briones N, Facista SJ, Mueller C, Cowan AJ, McBride MJ, Rodriguez ESR, Killian A, Dao T, Lamont J, Barron A, Su X, Hendricks WPD, Espina V, Von Hoff DD, O'Shaughnessy J, Rabinowitz JD | Med (New York, N.Y.) | 34223403 | Med | 2021 Jun 11 |
Quantitative flux analysis in mammals. | Bartman CR, TeSlaa T, Rabinowitz JD | Nature metabolism | 34211182 | Nat Metab | 2021 Jul |
Methionine synthase supports tumour tetrahydrofolate pools. | Ghergurovich JM, Xu X, Wang JZ, Yang L, Ryseck RP, Wang L, Rabinowitz JD | Nature metabolism | 34799699 | Nat Metab | 2021 Nov |
Impact of acute stress on murine metabolomics and metabolic flux. | Lee WD, Liang L, AbuSalim J, Jankowski CSR, Samarah LZ, Neinast MD, Rabinowitz JD | Proceedings of the National Academy of Sciences of the United States of America | 37186827 | Proc Natl Acad Sci U S A | 2023 May 23 |
Circulating metabolite homeostasis achieved through mass action. | Li X, Hui S, Mirek ET, Jonsson WO, Anthony TG, Lee WD, Zeng X, Jang C, Rabinowitz JD | Nature metabolism | 35058631 | Nat Metab | 2022 Jan |
Comprehensive quantification of fuel use by the failing and nonfailing human heart. | Murashige D, Jang C, Neinast M, Edwards JJ, Cowan A, Hyman MC, Rabinowitz JD, Frankel DS, Arany Z | Science (New York, N.Y.) | 33060364 | Science | 2020 Oct 16 |
Mitochondrial translation requires folate-dependent tRNA methylation. | Morscher RJ, Ducker GS, Li SH, Mayer JA, Gitai Z, Sperl W, Rabinowitz JD | Nature | 29364879 | Nature | 2018 Feb 1 |
Monitoring mammalian mitochondrial translation with MitoRiboSeq. | Li SH, Nofal M, Parsons LR, Rabinowitz JD, Gitai Z | Nature protocols | 33953394 | Nat Protoc | 2021 Jun |
Chemical Basis for Deuterium Labeling of Fat and NADPH. | Zhang Z, Chen L, Liu L, Su X, Rabinowitz JD | Journal of the American Chemical Society | 28911221 | J Am Chem Soc | 2017 Oct 18 |
mTOR Inhibition Restores Amino Acid Balance in Cells Dependent on Catabolism of Extracellular Protein. | Nofal M, Zhang K, Han S, Rabinowitz JD | Molecular cell | 28918901 | Mol Cell | 2017 Sep 21 |
Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate. | Zhao S, Jang C, Liu J, Uehara K, Gilbert M, Izzo L, Zeng X, Trefely S, Fernandez S, Carrer A, Miller KD, Schug ZT, Snyder NW, Gade TP, Titchenell PM, Rabinowitz JD, Wellen KE | Nature | 32214246 | Nature | 2020 Mar |
Serine Catabolism Feeds NADH when Respiration Is Impaired. | Yang L, Garcia Canaveras JC, Chen Z, Wang L, Liang L, Jang C, Mayr JA, Zhang Z, Ghergurovich JM, Zhan L, Joshi S, Hu Z, McReynolds MR, Su X, White E, Morscher RJ, Rabinowitz JD | Cell metabolism | 32187526 | Cell Metab | 2020 Apr 7 |
Novel Pyrrolo[3,2-d]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy. | Dekhne AS, Shah K, Ducker GS, Katinas JM, Wong-Roushar J, Nayeen MJ, Doshi A, Ning C, Bao X, Frühauf J, Liu J, Wallace-Povirk A, O'Connor C, Dzinic SH, White K, Kushner J, Kim S, Hüttemann M, Polin L, Rabinowitz JD, Li J, Hou Z, Dann CE 3rd, Gangjee A, Matherly LH | Molecular cancer therapeutics | 31289137 | Mol Cancer Ther | 2019 Oct |
Glucose feeds the TCA cycle via circulating lactate. | Hui S, Ghergurovich JM, Morscher RJ, Jang C, Teng X, Lu W, Esparza LA, Reya T, Le Zhan, Yanxiang Guo J, White E, Rabinowitz JD | Nature | 29045397 | Nature | 2017 Nov 2 |
Metabolite Exchange between Mammalian Organs Quantified in Pigs. | Jang C, Hui S, Zeng X, Cowan AJ, Wang L, Chen L, Morscher RJ, Reyes J, Frezza C, Hwang HY, Imai A, Saito Y, Okamoto K, Vaspoli C, Kasprenski L, Zsido GA 2nd, Gorman JH 3rd, Gorman RC, Rabinowitz JD | Cell metabolism | 36070684 | Cell Metab | 2022 Sep 6 |
Slow TCA flux and ATP production in primary solid tumours but not metastases. | Bartman CR, Weilandt DR, Shen Y, Lee WD, Han Y, TeSlaa T, Jankowski CSR, Samarah L, Park NR, da Silva-Diz V, Aleksandrova M, Gultekin Y, Marishta A, Wang L, Yang L, Roichman A, Bhatt V, Lan T, Hu Z, Xing X, Lu W, Davidson S, Wühr M, Vander Heiden MG, Herranz D, Guo JY, Kang Y, Rabinowitz JD | Nature | 36725930 | Nature | 2023 Feb |
mTORC1 promotes cell growth via m(6)A-dependent mRNA degradation. | Cho S, Lee G, Pickering BF, Jang C, Park JH, He L, Mathur L, Kim SS, Jung S, Tang HW, Monette S, Rabinowitz JD, Perrimon N, Jaffrey SR, Blenis J | Molecular cell | 33756105 | Mol Cell | 2021 May 20 |
The small intestine shields the liver from fructose-induced steatosis. | Jang C, Wada S, Yang S, Gosis B, Zeng X, Zhang Z, Shen Y, Lee G, Arany Z, Rabinowitz JD | Nature metabolism | 32694791 | Nat Metab | 2020 Jul |
Lactate: the ugly duckling of energy metabolism. | Rabinowitz JD, Enerbäck S | Nature metabolism | 32694798 | Nat Metab | 2020 Jul |
Restoring metabolism of myeloid cells reverses cognitive decline in ageing. | Minhas PS, Latif-Hernandez A, McReynolds MR, Durairaj AS, Wang Q, Rubin A, Joshi AU, He JQ, Gauba E, Liu L, Wang C, Linde M, Sugiura Y, Moon PK, Majeti R, Suematsu M, Mochly-Rosen D, Weissman IL, Longo FM, Rabinowitz JD, Andreasson KI | Nature | 33473210 | Nature | 2021 Feb |
The Source of Glycolytic Intermediates in Mammalian Tissues. | TeSlaa T, Bartman CR, Jankowski CSR, Zhang Z, Xu X, Xing X, Wang L, Lu W, Hui S, Rabinowitz JD | Cell metabolism | 33472024 | Cell Metab | 2021 Feb 2 |
NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism. | Chen L, Zhang Z, Hoshino A, Zheng HD, Morley M, Arany Z, Rabinowitz JD | Nature metabolism | 31058257 | Nat Metab | 2019 Mar |
Metabolite Measurement: Pitfalls to Avoid and Practices to Follow. | Lu W, Su X, Klein MS, Lewis IA, Fiehn O, Rabinowitz JD | Annual review of biochemistry | 28654323 | Annu Rev Biochem | 2017 Jun 20 |
Quantitative Fluxomics of Circulating Metabolites. | Hui S, Cowan AJ, Zeng X, Yang L, TeSlaa T, Li X, Bartman C, Zhang Z, Jang C, Wang L, Lu W, Rojas J, Baur J, Rabinowitz JD | Cell metabolism | 32791100 | Cell Metab | 2020 Oct 6 |
5,10-methenyltetrahydrofolate synthetase deficiency causes a neurometabolic disorder associated with microcephaly, epilepsy, and cerebral hypomyelination. | Rodan LH, Qi W, Ducker GS, Demirbas D, Laine R, Yang E, Walker MA, Eichler F, Rabinowitz JD, Anselm I, Berry GT, Undiagnosed Diseases Network (UDN) | Molecular genetics and metabolism | 30031689 | Mol Genet Metab | 2018 Sep |
Peak Annotation and Verification Engine for Untargeted LC-MS Metabolomics. | Wang L, Xing X, Chen L, Yang L, Su X, Rabitz H, Lu W, Rabinowitz JD | Analytical chemistry | 30586294 | Anal Chem | 2019 Feb 5 |
Quantitative Analysis of NAD Synthesis-Breakdown Fluxes. | Liu L, Su X, Quinn WJ 3rd, Hui S, Krukenberg K, Frederick DW, Redpath P, Zhan L, Chellappa K, White E, Migaud M, Mitchison TJ, Baur JA, Rabinowitz JD | Cell metabolism | 29685734 | Cell Metab | 2018 May 1 |
A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway. | Ghergurovich JM, García-Cañaveras JC, Wang J, Schmidt E, Zhang Z, TeSlaa T, Patel H, Chen L, Britt EC, Piqueras-Nebot M, Gomez-Cabrera MC, Lahoz A, Fan J, Beier UH, Kim H, Rabinowitz JD | Nature chemical biology | 32393898 | Nat Chem Biol | 2020 Jul |
Improved Annotation of Untargeted Metabolomics Data through Buffer Modifications That Shift Adduct Mass and Intensity. | Lu W, Xing X, Wang L, Chen L, Zhang S, McReynolds MR, Rabinowitz JD | Analytical chemistry | 32614575 | Anal Chem | 2020 Sep 1 |
Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth. | Yang L, TeSlaa T, Ng S, Nofal M, Wang L, Lan T, Zeng X, Cowan A, McBride M, Lu W, Davidson S, Liang G, Oh TG, Downes M, Evans R, Von Hoff D, Guo JY, Han H, Rabinowitz JD | Med (New York, N.Y.) | 35425930 | Med | 2022 Feb 11 |
NAD(+) flux is maintained in aged mice despite lower tissue concentrations. | McReynolds MR, Chellappa K, Chiles E, Jankowski C, Shen Y, Chen L, Descamps HC, Mukherjee S, Bhat YR, Lingala SR, Chu Q, Botolin P, Hayat F, Doke T, Susztak K, Thaiss CA, Lu W, Migaud ME, Su X, Rabinowitz JD, Baur JA | Cell systems | 34559996 | Cell Syst | 2021 Dec 15 |
Sex and genetic background define the metabolic, physiologic, and molecular response to protein restriction. | Green CL, Pak HH, Richardson NE, Flores V, Yu D, Tomasiewicz JL, Dumas SN, Kredell K, Fan JW, Kirsh C, Chaiyakul K, Murphy ME, Babygirija R, Barrett-Wilt GA, Rabinowitz J, Ong IM, Jang C, Simcox J, Lamming DW | Cell metabolism | 35108511 | Cell Metab | 2022 Feb 1 |
NAD precursors cycle between host tissues and the gut microbiome. | Chellappa K, McReynolds MR, Lu W, Zeng X, Makarov M, Hayat F, Mukherjee S, Bhat YR, Lingala SR, Shima RT, Descamps HC, Cox T, Ji L, Jankowski C, Chu Q, Davidson SM, Thaiss CA, Migaud ME, Rabinowitz JD, Baur JA | Cell metabolism | 36476934 | Cell Metab | 2022 Dec 6 |
Reprogramming neuroblastoma by diet-enhanced polyamine depletion. | Cherkaoui S, Yang L, McBride M, Turn CS, Lu W, Eigenmann C, Allen GE, Panasenko OO, Zhang L, Vu A, Liu K, Li Y, Gandhi OH, Surrey L, Wierer M, White E, Rabinowitz JD, Hogarty MD, Morscher RJ | bioRxiv : the preprint server for biology | 38260457 | bioRxiv | 2024 Jan 8 |
One-carbon unit supplementation fuels tumor-infiltrating T cells and augments checkpoint blockade. | Xu X, Chen Z, Bartman CR, Xing X, Olszewski K, Rabinowitz JD | bioRxiv : the preprint server for biology | 37961420 | bioRxiv | 2023 Nov 3 |
CRISPR-Cas9 mediated one-step disabling of pancreatogenesis in pigs. | Wu J, Vilarino M, Suzuki K, Okamura D, Bogliotti YS, Park I, Rowe J, McNabb B, Ross PJ, Belmonte JCI | Scientific reports | 28874671 | Sci Rep | 2017 Sep 5 |
Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction. | Suzuki K, Yamamoto M, Hernandez-Benitez R, Li Z, Wei C, Soligalla RD, Aizawa E, Hatanaka F, Kurita M, Reddy P, Ocampo A, Hishida T, Sakurai M, Nemeth AN, Nuñez Delicado E, Campistol JM, Magistretti P, Guillen P, Rodriguez Esteban C, Gong J, Yuan Y, Gu Y, Liu GH, López-Otín C, Wu J, Zhang K, Izpisua Belmonte JC | Cell research | 31444470 | Cell Res | 2019 Oct |
Deconstructing the pluripotency gene regulatory network. | Li M, Izpisua Belmonte JC | Nature cell biology | 29593328 | Nat Cell Biol | 2018 Apr |
Functional sensory circuits built from neurons of two species. | Throesch BT, Bin Imtiaz MK, Muñoz-Castañeda R, Sakurai M, Hartzell AL, James KN, Rodriguez AR, Martin G, Lippi G, Kupriyanov S, Wu Z, Osten P, Izpisua Belmonte JC, Wu J, Baldwin KK | Cell | 38670072 | Cell | 2024 Apr 25 |
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Macrophage Biology, Classification, and Phenotype in Cardiovascular Disease: JACC Macrophage in CVD Series (Part 1). | Williams JW, Giannarelli C, Rahman A, Randolph GJ, Kovacic JC | Journal of the American College of Cardiology | 30360826 | J Am Coll Cardiol | 2018 Oct 30 |
Lymphoid Aggregates Remodel Lymphatic Collecting Vessels that Serve Mesenteric Lymph Nodes in Crohn Disease. | Randolph GJ, Bala S, Rahier JF, Johnson MW, Wang PL, Nalbantoglu I, Dubuquoy L, Chau A, Pariente B, Kartheuser A, Zinselmeyer BH, Colombel JF | The American journal of pathology | 27746181 | Am J Pathol | 2016 Dec |
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Limited Macrophage Positional Dynamics in Progressing or Regressing Murine Atherosclerotic Plaques-Brief Report. | Williams JW, Martel C, Potteaux S, Esaulova E, Ingersoll MA, Elvington A, Saunders BT, Huang LH, Habenicht AJ, Zinselmeyer BH, Randolph GJ | Arteriosclerosis, thrombosis, and vascular biology | 29903736 | Arterioscler Thromb Vasc Biol | 2018 Aug |
Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity. | Westerterp M, Gautier EL, Ganda A, Molusky MM, Wang W, Fotakis P, Wang N, Randolph GJ, D'Agati VD, Yvan-Charvet L, Tall AR | Cell metabolism | 28479366 | Cell Metab | 2017 Jun 6 |
Microbiota-Dependent Sequelae of Acute Infection Compromise Tissue-Specific Immunity. | Fonseca DM, Hand TW, Han SJ, Gerner MY, Glatman Zaretsky A, Byrd AL, Harrison OJ, Ortiz AM, Quinones M, Trinchieri G, Brenchley JM, Brodsky IE, Germain RN, Randolph GJ, Belkaid Y | Cell | 26451485 | Cell | 2015 Oct 8 |
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Lymphatic network remodeling after small bowel resection. | Onufer EJ, Czepielewski R, Seiler KM, Erlich E, Courtney CM, Bustos A, Randolph GJ, Warner BW | Journal of pediatric surgery | 30879758 | J Pediatr Surg | 2019 Jun |
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Myeloid-specific Asxl2 deletion limits diet-induced obesity by regulating energy expenditure. | Zou W, Rohatgi N, Brestoff JR, Moley JR, Li Y, Williams JW, Alippe Y, Pan H, Pietka TA, Mbalaviele G, Newberry EP, Davidson NO, Dey A, Shoghi KI, Head RD, Wickline SA, Randolph GJ, Abumrad NA, Teitelbaum SL | The Journal of clinical investigation | 32310225 | J Clin Invest | 2020 May 1 |
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Acetylcholine is released in the basolateral amygdala in response to predictors of reward and enhances the learning of cue-reward contingency. | Crouse RB, Kim K, Batchelor HM, Girardi EM, Kamaletdinova R, Chan J, Rajebhosale P, Pittenger ST, Role LW, Talmage DA, Jing M, Li Y, Gao XB, Mineur YS, Picciotto MR | eLife | 32945260 | Elife | 2020 Sep 18 |
Effects of nicotine on DARPP-32 and CaMKII signaling relevant to addiction. | Lee AM, Picciotto MR | Advances in pharmacology (San Diego, Calif.) | 33706940 | Adv Pharmacol | 2021 |
Hippocampal acetylcholine modulates stress-related behaviors independent of specific cholinergic inputs. | Mineur YS, Mose TN, Vanopdenbosch L, Etherington IM, Ogbejesi C, Islam A, Pineda CM, Crouse RB, Zhou W, Thompson DC, Bentham MP, Picciotto MR | Molecular psychiatry | 34997190 | Mol Psychiatry | 2022 Mar |
Sex differences in stress-induced alcohol intake: a review of preclinical studies focused on amygdala and inflammatory pathways. | Mineur YS, Garcia-Rivas V, Thomas MA, Soares AR, McKee SA, Picciotto MR | Psychopharmacology | 35359158 | Psychopharmacology (Berl) | 2022 Jul |
Origin and Function of Stress-Induced IL-6 in Murine Models. | Qing H, Desrouleaux R, Israni-Winger K, Mineur YS, Fogelman N, Zhang C, Rashed S, Palm NW, Sinha R, Picciotto MR, Perry RJ, Wang A | Cell | 32610084 | Cell | 2020 Jul 23 |
microRNA-33 maintains adaptive thermogenesis via enhanced sympathetic nerve activity. | Horie T, Nakao T, Miyasaka Y, Nishino T, Matsumura S, Nakazeki F, Ide Y, Kimura M, Tsuji S, Rodriguez RR, Watanabe T, Yamasaki T, Xu S, Otani C, Miyagawa S, Matsushita K, Sowa N, Omori A, Tanaka J, Nishimura C, Nishiga M, Kuwabara Y, Baba O, Watanabe S, Nishi H, Nakashima Y, Picciotto MR, Inoue H, Watanabe D, Nakamura K, Sasaki T, Kimura T, Ono K | Nature communications | 33594062 | Nat Commun | 2021 Feb 16 |
Sex Differences in the Ventral Tegmental Area and Nucleus Accumbens Proteome at Baseline and Following Nicotine Exposure. | Lee AM, Mansuri MS, Wilson RS, Lam TT, Nairn AC, Picciotto MR | Frontiers in molecular neuroscience | 34335180 | Front Mol Neurosci | 2021 |
The role of acetylcholine in negative encoding bias: Too much of a good thing? | Mineur YS, Picciotto MR | The European journal of neuroscience | 31821620 | Eur J Neurosci | 2021 Jan |
Cumulative Effects of Social Stress on Reward-Guided Actions and Prefrontal Cortical Activity. | Barthas F, Hu MY, Siniscalchi MJ, Ali F, Mineur YS, Picciotto MR, Kwan AC | Biological psychiatry | 32276717 | Biol Psychiatry | 2020 Oct 1 |
How can I measure brain acetylcholine levels in vivo? Advantages and caveats of commonly used approaches. | Mineur YS, Picciotto MR | Journal of neurochemistry | 37621094 | J Neurochem | 2023 Oct |
Impaired hypocretin/orexin system alters responses to salient stimuli in obese male mice. | Tan Y, Hang F, Liu ZW, Stoiljkovic M, Wu M, Tu Y, Han W, Lee AM, Kelley C, Hajós M, Lu L, de Lecea L, De Araujo I, Picciotto MR, Horvath TL, Gao XB | The Journal of clinical investigation | 32516139 | J Clin Invest | 2020 Sep 1 |
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Vertical silicon nanowires as a universal platform for delivering biomolecules into living cells. | Shalek AK, Robinson JT, Karp ES, Lee JS, Ahn DR, Yoon MH, Sutton A, Jorgolli M, Gertner RS, Gujral TS, MacBeath G, Yang EG, Park H | Proceedings of the National Academy of Sciences of the United States of America | 20080678 | Proc Natl Acad Sci U S A | 2010 Feb 2 |
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Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12. | Wu Y, West AP Jr, Kim HJ, Thornton ME, Ward AB, Bjorkman PJ | Cell reports | 24316082 | Cell Rep | 2013 Dec 12 |
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Development of the enteric nervous system in the moth. I. Diversity of cell types and the embryonic expression of FMRFamide-related neuropeptides. | Copenhaver PF, Taghert PH | Developmental biology | 2909410 | Dev Biol | 1989 Jan |
Metamorphosis of tangential visual system neurons in Drosophila. | Taghert PH, Roberts ME, Renn SC, Jacobs PS | Developmental biology | 10837134 | Dev Biol | 2000 Jun 15 |
Drosophila MEF2, a transcription factor that is essential for myogenesis. | Bour BA, O'Brien MA, Lockwood WL, Goldstein ES, Bodmer R, Taghert PH, Abmayr SM, Nguyen HT | Genes & development | 7729689 | Genes Dev | 1995 Mar 15 |
Segment-specific modifications of a neuropeptide phenotype in embryonic neurons of the moth, Manduca sexta. | Wall JB, Taghert PH | The Journal of comparative neurology | 1918442 | J Comp Neurol | 1991 Jul 15 |
The timing of initial neuropeptide expression by an identified insect neuron does not depend on interactions with its normal peripheral target. | Wall JB, Taghert PH | Journal of neurobiology | 1795159 | J Neurobiol | 1991 Dec |
Developmental neurobiology. Axon outgrowth in vertebrates. | Taghert PH, Lichtman JW | Nature | 3960104 | Nature | 1986 Mar 20-26 |
Lithium- and valproate-induced alterations in circadian locomotor behavior in Drosophila. | Dokucu ME, Yu L, Taghert PH | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology | 15956996 | Neuropsychopharmacology | 2005 Dec |
Organization of the Drosophila circadian control circuit. | Nitabach MN, Taghert PH | Current biology : CB | 18211849 | Curr Biol | 2008 Jan 22 |
Interaction of Drosophila melanogaster prohormone convertase 2 and 7B2. Insect cell-specific processing and secretion. | Hwang JR, Siekhaus DE, Fuller RS, Taghert PH, Lindberg I | The Journal of biological chemistry | 10749852 | J Biol Chem | 2000 Jun 9 |
Mechanisms of clock output in the Drosophila circadian pacemaker system. | Taghert PH, Shafer OT | Journal of biological rhythms | 17107935 | J Biol Rhythms | 2006 Dec |
PHM is required for normal developmental transitions and for biosynthesis of secretory peptides in Drosophila. | Jiang N, Kolhekar AS, Jacobs PS, Mains RE, Eipper BA, Taghert PH | Developmental biology | 10993678 | Dev Biol | 2000 Oct 1 |
Synchronous Drosophila circadian pacemakers display nonsynchronous Ca²⁺ rhythms in vivo. | Liang X, Holy TE, Taghert PH | Science (New York, N.Y.) | 26917772 | Science | 2016 Feb 26 |
Circadian rhythms: in the loop at last. | Van Gelder RN, Herzog ED, Schwartz WJ, Taghert PH | Science (New York, N.Y.) | 12791982 | Science | 2003 Jun 6 |
A peritracheal neuropeptide system in insects: release of myomodulin-like peptides at ecdysis. | O'Brien MA, Taghert PH | The Journal of experimental biology | 9405303 | J Exp Biol | 1998 Jan |
Formation of the transverse nerve in moth embryos. II. Stereotyped growth by the axons of identified neuroendocrine neurons. | Carr JN, Taghert PH | Developmental biology | 3197922 | Dev Biol | 1988 Dec |
Characterization and cloning of tripeptidyl peptidase II from the fruit fly, Drosophila melanogaster. | Renn SC, Tomkinson B, Taghert PH | The Journal of biological chemistry | 9668104 | J Biol Chem | 1998 Jul 24 |
Neurogenesis in the insect enteric nervous system: generation of premigratory neurons from an epithelial placode. | Copenhaver PF, Taghert PH | Development (Cambridge, England) | 2209463 | Development | 1990 May |
Molecular genetic analysis of the FMRFamide-related neuropeptides in Drosophila. | Taghert PH, O'Brien MA, Schneider LE, Roberts MS | Progress in brain research | 1302876 | Prog Brain Res | 1992 |
Organization and expression of the Drosophila Phe-Met-Arg-Phe-NH2 neuropeptide gene. | Schneider LE, Taghert PH | The Journal of biological chemistry | 2324103 | J Biol Chem | 1990 Apr 25 |
Cell type-specific transcriptional regulation of the Drosophila FMRFamide neuropeptide gene. | Schneider LE, Roberts MS, Taghert PH | Neuron | 8439413 | Neuron | 1993 Feb |
Regulators acting in combinatorial codes also act independently in single differentiating neurons. | Allan DW, Park D, St Pierre SE, Taghert PH, Thor S | Neuron | 15748845 | Neuron | 2005 Mar 3 |
A novel diuretic hormone receptor in Drosophila: evidence for conservation of CGRP signaling. | Johnson EC, Shafer OT, Trigg JS, Park J, Schooley DA, Dow JA, Taghert PH | The Journal of experimental biology | 15781884 | J Exp Biol | 2005 Apr |
Guidance of pioneer growth cones: filopodial contacts and coupling revealed with an antibody to Lucifer Yellow. | Taghert PH, Bastiani MJ, Ho RK, Goodman CS | Developmental biology | 7152111 | Dev Biol | 1982 Dec |
Cell determination and regulation during development of neuroblasts and neurones in grasshopper embryo. | Taghert PH, Doe CQ, Goodman CS | Nature | 6690996 | Nature | 1984 Jan 12-18 |
Ap-let neurons--a peptidergic circuit potentially controlling ecdysial behavior in Drosophila. | Park D, Han M, Kim YC, Han KA, Taghert PH | Developmental biology | 15081360 | Dev Biol | 2004 May 1 |
Transcriptomic landscape of mammalian ventral pallidum at single-cell resolution. | Yang L, Fang LZ, Lynch MR, Xu CS, Hahm H, Zhang Y, Heitmeier MR, Costa V, Samineni VK, Creed MC | bioRxiv : the preprint server for biology | 38826431 | bioRxiv | 2024 Sep 28 |
Widely distributed Drosophila G-protein-coupled receptor (CG7887) is activated by endogenous tachykinin-related peptides. | Birse RT, Johnson EC, Taghert PH, Nässel DR | Journal of neurobiology | 16193493 | J Neurobiol | 2006 Jan |
Drosophila neuropeptide signaling. | Taghert PH, Veenstra JA | Advances in genetics | 12779250 | Adv Genet | 2003 |
Origins of the insect enteric nervous system: differentiation of the enteric ganglia from a neurogenic epithelium. | Copenhaver PF, Taghert PH | Development (Cambridge, England) | 1811931 | Development | 1991 Dec |
Pair-rule expression of a cell surface molecule during gastrulation of the moth embryo. | Carr JN, Taghert PH | Development (Cambridge, England) | 2627891 | Development | 1989 Sep |
Cell type-specific regulation of the Drosophila FMRF-NH2 neuropeptide gene by Apterous, a LIM homeodomain transcription factor. | Benveniste RJ, Thor S, Thomas JB, Taghert PH | Development (Cambridge, England) | 9806924 | Development | 1998 Dec |
FMRFamide neuropeptides and neuropeptide-associated enzymes in Drosophila. | Taghert PH | Microscopy research and technique | 10332726 | Microsc Res Tech | 1999 Apr 15 |
A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila. | Renn SC, Park JH, Rosbash M, Hall JC, Taghert PH | Cell | 10619432 | Cell | 1999 Dec 23 |
In situ hybridization analysis of the FMRFamide neuropeptide gene in Drosophila. II. Constancy in the cellular pattern of expression during metamorphosis. | O'Brien MA, Schneider LE, Taghert PH | The Journal of comparative neurology | 1672877 | J Comp Neurol | 1991 Feb 22 |
Circadian biology: a neuropeptide is bound to activate its receptor. | Taghert PH | Current biology : CB | 19706280 | Curr Biol | 2009 Aug 25 |
Peptidergic neurosecretory cells in insects: organization and control by the bHLH protein DIMMED. | Park D, Taghert PH | General and comparative endocrinology | 19135054 | Gen Comp Endocrinol | 2009 May 15 |
Circadian rhythms: biological clocks work in phospho-time. | Duvall LB, Taghert PH | Current biology : CB | 21549947 | Curr Biol | 2011 May 10 |
Drosophila CG8422 encodes a functional diuretic hormone receptor. | Johnson EC, Bohn LM, Taghert PH | The Journal of experimental biology | 14747406 | J Exp Biol | 2004 Feb |
Polyphasic circadian neural circuits drive differential activities in multiple downstream rhythmic centers. | Liang X, Holy TE, Taghert PH | Current biology : CB | 36610393 | Curr Biol | 2023 Jan 23 |
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Drosophila uses two distinct neuropeptide amidating enzymes, dPAL1 and dPAL2. | Han M, Park D, Vanderzalm PJ, Mains RE, Eipper BA, Taghert PH | Journal of neurochemistry | 15198673 | J Neurochem | 2004 Jul |
Identification of Drosophila neuropeptide receptors by G protein-coupled receptors-beta-arrestin2 interactions. | Johnson EC, Bohn LM, Barak LS, Birse RT, Nässel DR, Caron MG, Taghert PH | The Journal of biological chemistry | 14555656 | J Biol Chem | 2003 Dec 26 |
How does the circadian clock send timing information to the brain? | Taghert PH | Seminars in cell & developmental biology | 11463217 | Semin Cell Dev Biol | 2001 Aug |
PDF receptor signaling in Drosophila contributes to both circadian and geotactic behaviors. | Mertens I, Vandingenen A, Johnson EC, Shafer OT, Li W, Trigg JS, De Loof A, Schoofs L, Taghert PH | Neuron | 16242402 | Neuron | 2005 Oct 20 |
The bHLH protein Dimmed controls neuroendocrine cell differentiation in Drosophila. | Hewes RS, Park D, Gauthier SA, Schaefer AM, Taghert PH | Development (Cambridge, England) | 12642483 | Development | 2003 May |
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In situ hybridization analysis of the FMRFamide neuropeptide gene in Drosophila. I. Restricted expression in embryonic and larval stages. | Schneider LE, O'Brien MA, Taghert PH | The Journal of comparative neurology | 1672876 | J Comp Neurol | 1991 Feb 22 |
Genetic analysis of the Drosophila ellipsoid body neuropil: organization and development of the central complex. | Renn SC, Armstrong JD, Yang M, Wang Z, An X, Kaiser K, Taghert PH | Journal of neurobiology | 10512977 | J Neurobiol | 1999 Nov 5 |
Cell type-specific regulatory sequences control expression of the Drosophila FMRF-NH2 neuropeptide gene. | Benveniste RJ, Taghert PH | Journal of neurobiology | 10084686 | J Neurobiol | 1999 Mar |
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Developmental neurobiology. Trophic factor theory matures. | Lichtman JW, Taghert PH | Nature | 3031503 | Nature | 1987 Mar 26-Apr 1 |
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Morning and Evening Circadian Pacemakers Independently Drive Premotor Centers via a Specific Dopamine Relay. | Liang X, Ho MCW, Zhang Y, Li Y, Wu MN, Holy TE, Taghert PH | Neuron | 30981533 | Neuron | 2019 May 22 |
A Series of Suppressive Signals within the Drosophila Circadian Neural Circuit Generates Sequential Daily Outputs. | Liang X, Holy TE, Taghert PH | Neuron | 28552314 | Neuron | 2017 Jun 21 |
Circadian pacemaker neurons display cophasic rhythms in basal calcium level and in fast calcium fluctuations. | Liang X, Holy TE, Taghert PH | Proceedings of the National Academy of Sciences of the United States of America | 35446620 | Proc Natl Acad Sci U S A | 2022 Apr 26 |
Kinesin-1 regulates synaptic strength by mediating the delivery, removal, and redistribution of AMPA receptors. | Hoerndli FJ, Maxfield DA, Brockie PJ, Mellem JE, Jensen E, Wang R, Madsen DM, Maricq AV | Neuron | 24360545 | Neuron | 2013 Dec 18 |
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NRAP-1 Is a Presynaptically Released NMDA Receptor Auxiliary Protein that Modifies Synaptic Strength. | Lei N, Mellem JE, Brockie PJ, Madsen DM, Maricq AV | Neuron | 29224722 | Neuron | 2017 Dec 20 |
MAPK signaling and a mobile scaffold complex regulate AMPA receptor transport to modulate synaptic strength. | Hoerndli FJ, Brockie PJ, Wang R, Mellem JE, Kallarackal A, Doser RL, Pierce DM, Madsen DM, Maricq AV | Cell reports | 35354038 | Cell Rep | 2022 Mar 29 |
Neuronal Activity and CaMKII Regulate Kinesin-Mediated Transport of Synaptic AMPARs. | Hoerndli FJ, Wang R, Mellem JE, Kallarackal A, Brockie PJ, Thacker C, Madsen DM, Maricq AV | Neuron | 25843407 | Neuron | 2015 Apr 22 |
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A CRISPR/Cas9-Engineered ARID1A-Deficient Human Gastric Cancer Organoid Model Reveals Essential and Nonessential Modes of Oncogenic Transformation. | Lo YH, Kolahi KS, Du Y, Chang CY, Krokhotin A, Nair A, Sobba WD, Karlsson K, Jones SJ, Longacre TA, Mah AT, Tercan B, Sockell A, Xu H, Seoane JA, Chen J, Shmulevich I, Weissman JS, Curtis C, Califano A, Fu H, Crabtree GR, Kuo CJ | Cancer discovery | 33451982 | Cancer Discov | 2021 Jun |
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Germline-mediated immunoediting sculpts breast cancer subtypes and metastatic proclivity. | Houlahan KE, Khan A, Greenwald NF, West RB, Angelo M, Curtis C | bioRxiv : the preprint server for biology | 36993286 | bioRxiv | 2023 Mar 16 |
The Mettl3 epitranscriptomic writer amplifies p53 stress responses. | Raj N, Wang M, Seoane JA, Zhao RL, Kaiser AM, Moonie NA, Demeter J, Boutelle AM, Kerr CH, Mulligan AS, Moffatt C, Zeng SX, Lu H, Barna M, Curtis C, Chang HY, Jackson PK, Attardi LD | Molecular cell | 35512709 | Mol Cell | 2022 Jul 7 |
Most cancers carry a substantial deleterious load due to Hill-Robertson interference. | Tilk S, Tkachenko S, Curtis C, Petrov DA, McFarland CD | eLife | 36047771 | Elife | 2022 Sep 1 |
Deterministic evolution and stringent selection during preneoplasia. | Karlsson K, Przybilla MJ, Kotler E, Khan A, Xu H, Karagyozova K, Sockell A, Wong WH, Liu K, Mah A, Lo YH, Lu B, Houlahan KE, Ma Z, Suarez CJ, Barnes CP, Kuo CJ, Curtis C | Nature | 37258665 | Nature | 2023 Jun |
Germline-mediated immunoediting sculpts breast cancer subtypes and metastatic proclivity. | Houlahan KE, Khan A, Greenwald NF, Vivas CS, West RB, Angelo M, Curtis C | Science (New York, N.Y.) | 38815010 | Science | 2024 May 31 |
Cancers adapt to their mutational load by buffering protein misfolding stress. | Tilk S, Frydman J, Curtis C, Petrov DA | eLife | 39585785 | Elife | 2024 Nov 25 |
A High-Dimensional Window into the Micro-Environment of Triple Negative Breast Cancer. | Nederlof I, Horlings HM, Curtis C, Kok M | Cancers | 33467084 | Cancers (Basel) | 2021 Jan 16 |
Characterizing the ecological and evolutionary dynamics of cancer. | Zahir N, Sun R, Gallahan D, Gatenby RA, Curtis C | Nature genetics | 32719518 | Nat Genet | 2020 Aug |
Multi-cancer analysis of clonality and the timing of systemic spread in paired primary tumors and metastases. | Hu Z, Li Z, Ma Z, Curtis C | Nature genetics | 32424352 | Nat Genet | 2020 Jul |
Looking backward in time to define the chronology of metastasis. | Hu Z, Curtis C | Nature communications | 32587245 | Nat Commun | 2020 Jun 25 |
Cell of Origin Influences Pancreatic Cancer Subtype. | Flowers BM, Xu H, Mulligan AS, Hanson KJ, Seoane JA, Vogel H, Curtis C, Wood LD, Attardi LD | Cancer discovery | 34009137 | Cancer Discov | 2021 Mar |
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Targeted chemotherapy overcomes drug resistance in melanoma. | Yue J, Vendramin R, Liu F, Lopez O, Valencia MG, Gomes Dos Santos H, Gaidosh G, Beckedorff F, Blumenthal E, Speroni L, Nimer SD, Marine JC, Shiekhattar R | Genes & development | 32241802 | Genes Dev | 2020 May 1 |
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The Human Integrator Complex Facilitates Transcriptional Elongation by Endonucleolytic Cleavage of Nascent Transcripts. | Beckedorff F, Blumenthal E, daSilva LF, Aoi Y, Cingaram PR, Yue J, Zhang A, Dokaneheifard S, Valencia MG, Gaidosh G, Shilatifard A, Shiekhattar R | Cell reports | 32697989 | Cell Rep | 2020 Jul 21 |
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NELF Regulates a Promoter-Proximal Step Distinct from RNA Pol II Pause-Release. | Aoi Y, Smith ER, Shah AP, Rendleman EJ, Marshall SA, Woodfin AR, Chen FX, Shiekhattar R, Shilatifard A | Molecular cell | 32155413 | Mol Cell | 2020 Apr 16 |
Generating Patient-Derived Gliomas within Cerebral Organoids. | Linkous A, Fine HA | STAR protocols | 33103125 | STAR Protoc | 2020 Jun 19 |
Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate. | Lu TM, Houghton S, Magdeldin T, Durán JGB, Minotti AP, Snead A, Sproul A, Nguyen DT, Xiang J, Fine HA, Rosenwaks Z, Studer L, Rafii S, Agalliu D, Redmond D, Lis R | Proceedings of the National Academy of Sciences of the United States of America | 33542154 | Proc Natl Acad Sci U S A | 2021 Feb 23 |
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Modeling Patient-Derived Glioblastoma with Cerebral Organoids. | Linkous A, Balamatsias D, Snuderl M, Edwards L, Miyaguchi K, Milner T, Reich B, Cohen-Gould L, Storaska A, Nakayama Y, Schenkein E, Singhania R, Cirigliano S, Magdeldin T, Lin Y, Nanjangud G, Chadalavada K, Pisapia D, Liston C, Fine HA | Cell reports | 30893594 | Cell Rep | 2019 Mar 19 |
Malignant Gliomas: Simplifying the Complexity. | Fine HA | Cancer discovery | 31792122 | Cancer Discov | 2019 Dec |
Reirradiation for Recurrent Glioblastoma: What We Know and What We Do Not. | Knisely JPS, Fine HA | Journal of clinical oncology : official journal of the American Society of Clinical Oncology | 36260825 | J Clin Oncol | 2023 Feb 20 |
Diffuse Glioma Heterogeneity and Its Therapeutic Implications. | Nicholson JG, Fine HA | Cancer discovery | 33558264 | Cancer Discov | 2021 Mar |
Detailed longitudinal sampling of glioma stem cells in situ reveals Chr7 gain and Chr10 loss as repeated events in primary tumor formation and recurrence. | Baysan M, Woolard K, Cam MC, Zhang W, Song H, Kotliarova S, Balamatsias D, Linkous A, Ahn S, Walling J, Belova GI, Fine HA | International journal of cancer | 28710771 | Int J Cancer | 2017 Nov 15 |
Tumor Microenvironment Is Critical for the Maintenance of Cellular States Found in Primary Glioblastomas. | Pine AR, Cirigliano SM, Nicholson JG, Hu Y, Linkous A, Miyaguchi K, Edwards L, Singhania R, Schwartz TH, Ramakrishna R, Pisapia DJ, Snuderl M, Elemento O, Fine HA | Cancer discovery | 32253265 | Cancer Discov | 2020 Jul |
Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution. | Pine AR, Cirigliano SM, Singhania R, Nicholson J, da Silva B, Leslie CS, Fine HA | Cancer research | 36877162 | Cancer Res | 2023 May 15 |
Nuclear condensates in YAP1-driven ependymoma. | Dadras MS, Fine HA | Nature cell biology | 36732630 | Nat Cell Biol | 2023 Feb |
Chronic hypoxia remodels the tumor microenvironment to support glioma stem cell growth. | Nicholson JG, Cirigliano S, Singhania R, Haywood C, Shahidi Dadras M, Yoshimura M, Vanderbilt D, Liechty B, Fine HA | Acta neuropathologica communications | 38528608 | Acta Neuropathol Commun | 2024 Mar 25 |
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A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas. | Ryan RJH, Petrovic J, Rausch DM, Zhou Y, Lareau CA, Kluk MJ, Christie AL, Lee WY, Tarjan DR, Guo B, Donohue LKH, Gillespie SM, Nardi V, Hochberg EP, Blacklow SC, Weinstock DM, Faryabi RB, Bernstein BE, Aster JC, Pear WS | Cell reports | 29045844 | Cell Rep | 2017 Oct 17 |
Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance. | Liau BB, Sievers C, Donohue LK, Gillespie SM, Flavahan WA, Miller TE, Venteicher AS, Hebert CH, Carey CD, Rodig SJ, Shareef SJ, Najm FJ, van Galen P, Wakimoto H, Cahill DP, Rich JN, Aster JC, Suvà ML, Patel AP, Bernstein BE | Cell stem cell | 27989769 | Cell Stem Cell | 2017 Feb 2 |
Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing. | Nuñez JK, Chen J, Pommier GC, Cogan JZ, Replogle JM, Adriaens C, Ramadoss GN, Shi Q, Hung KL, Samelson AJ, Pogson AN, Kim JYS, Chung A, Leonetti MD, Chang HY, Kampmann M, Bernstein BE, Hovestadt V, Gilbert LA, Weissman JS | Cell | 33838111 | Cell | 2021 Apr 29 |
Integrative dissection of gene regulatory elements at base resolution. | Chen Z, Javed N, Moore M, Wu J, Sun G, Vinyard M, Collins A, Pinello L, Najm FJ, Bernstein BE | Cell genomics | 37388913 | Cell Genom | 2023 Jun 14 |
Chromatin complex dependencies reveal targeting opportunities in leukemia. | Najm FJ, DeWeirdt P, Moore MM, Bevill SM, El Farran CA, Macias KA, Hegde M, Waterbury AL, Liau BB, van Galen P, Doench JG, Bernstein BE | Nature communications | 36707513 | Nat Commun | 2023 Jan 27 |
Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity. | van Galen P, Hovestadt V, Wadsworth Ii MH, Hughes TK, Griffin GK, Battaglia S, Verga JA, Stephansky J, Pastika TJ, Lombardi Story J, Pinkus GS, Pozdnyakova O, Galinsky I, Stone RM, Graubert TA, Shalek AK, Aster JC, Lane AA, Bernstein BE | Cell | 30827681 | Cell | 2019 Mar 7 |
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq. | Filbin MG, Tirosh I, Hovestadt V, Shaw ML, Escalante LE, Mathewson ND, Neftel C, Frank N, Pelton K, Hebert CM, Haberler C, Yizhak K, Gojo J, Egervari K, Mount C, van Galen P, Bonal DM, Nguyen QD, Beck A, Sinai C, Czech T, Dorfer C, Goumnerova L, Lavarino C, Carcaboso AM, Mora J, Mylvaganam R, Luo CC, Peyrl A, Popović M, Azizi A, Batchelor TT, Frosch MP, Martinez-Lage M, Kieran MW, Bandopadhayay P, Beroukhim R, Fritsch G, Getz G, Rozenblatt-Rosen O, Wucherpfennig KW, Louis DN, Monje M, Slavc I, Ligon KL, Golub TR, Regev A, Bernstein BE, Suvà ML | Science (New York, N.Y.) | 29674595 | Science | 2018 Apr 20 |
Epigenetic plasticity and the hallmarks of cancer. | Flavahan WA, Gaskell E, Bernstein BE | Science (New York, N.Y.) | 28729483 | Science | 2017 Jul 21 |
Resolving medulloblastoma cellular architecture by single-cell genomics. | Hovestadt V, Smith KS, Bihannic L, Filbin MG, Shaw ML, Baumgartner A, DeWitt JC, Groves A, Mayr L, Weisman HR, Richman AR, Shore ME, Goumnerova L, Rosencrance C, Carter RA, Phoenix TN, Hadley JL, Tong Y, Houston J, Ashmun RA, DeCuypere M, Sharma T, Flasch D, Silkov A, Ligon KL, Pomeroy SL, Rivera MN, Rozenblatt-Rosen O, Rusert JM, Wechsler-Reya RJ, Li XN, Peyrl A, Gojo J, Kirchhofer D, Lötsch D, Czech T, Dorfer C, Haberler C, Geyeregger R, Halfmann A, Gawad C, Easton J, Pfister SM, Regev A, Gajjar A, Orr BA, Slavc I, Robinson GW, Bernstein BE, Suvà ML, Northcott PA | Nature | 31341285 | Nature | 2019 Aug |
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer. | Puram SV, Tirosh I, Parikh AS, Patel AP, Yizhak K, Gillespie S, Rodman C, Luo CL, Mroz EA, Emerick KS, Deschler DG, Varvares MA, Mylvaganam R, Rozenblatt-Rosen O, Rocco JW, Faquin WC, Lin DT, Regev A, Bernstein BE | Cell | 29198524 | Cell | 2017 Dec 14 |
An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma. | Neftel C, Laffy J, Filbin MG, Hara T, Shore ME, Rahme GJ, Richman AR, Silverbush D, Shaw ML, Hebert CM, Dewitt J, Gritsch S, Perez EM, Gonzalez Castro LN, Lan X, Druck N, Rodman C, Dionne D, Kaplan A, Bertalan MS, Small J, Pelton K, Becker S, Bonal D, Nguyen QD, Servis RL, Fung JM, Mylvaganam R, Mayr L, Gojo J, Haberler C, Geyeregger R, Czech T, Slavc I, Nahed BV, Curry WT, Carter BS, Wakimoto H, Brastianos PK, Batchelor TT, Stemmer-Rachamimov A, Martinez-Lage M, Frosch MP, Stamenkovic I, Riggi N, Rheinbay E, Monje M, Rozenblatt-Rosen O, Cahill DP, Patel AP, Hunter T, Verma IM, Ligon KL, Louis DN, Regev A, Bernstein BE, Tirosh I, Suvà ML | Cell | 31327527 | Cell | 2019 Aug 8 |
Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer. | Johnstone SE, Reyes A, Qi Y, Adriaens C, Hegazi E, Pelka K, Chen JH, Zou LS, Drier Y, Hecht V, Shoresh N, Selig MK, Lareau CA, Iyer S, Nguyen SC, Joyce EF, Hacohen N, Irizarry RA, Zhang B, Aryee MJ, Bernstein BE | Cell | 32841603 | Cell | 2020 Sep 17 |
Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance. | Eyler CE, Matsunaga H, Hovestadt V, Vantine SJ, van Galen P, Bernstein BE | Genome biology | 32669109 | Genome Biol | 2020 Jul 15 |
Modeling epigenetic lesions that cause gliomas. | Rahme GJ, Javed NM, Puorro KL, Xin S, Hovestadt V, Johnstone SE, Bernstein BE | Cell | 37494934 | Cell | 2023 Aug 17 |
Dissection of a CTCF topological boundary uncovers principles of enhancer-oncogene regulation. | Kim KL, Rahme GJ, Goel VY, El Farran CA, Hansen AS, Bernstein BE | Molecular cell | 38452764 | Mol Cell | 2024 Apr 4 |
Impact of supraphysiologic MDM2 expression on chromatin networks and therapeutic responses in sarcoma. | Bevill SM, Casaní-Galdón S, El Farran CA, Cytrynbaum EG, Macias KA, Oldeman SE, Oliveira KJ, Moore MM, Hegazi E, Adriaens C, Najm FJ, Demetri GD, Cohen S, Mullen JT, Riggi N, Johnstone SE, Bernstein BE | Cell genomics | 37492096 | Cell Genom | 2023 Jul 12 |
Programs, Origins, and Niches of Immunomodulatory Myeloid Cells in Gliomas. | Miller TE, El Farran CA, Couturier CP, Chen Z, D'Antonio JP, Verga J, Villanueva MA, Castro LNG, Tong YE, Saadi TA, Chiocca AN, Fischer DS, Heiland DH, Guerriero JL, Petrecca K, Suva ML, Shalek AK, Bernstein BE | bioRxiv : the preprint server for biology | 37961527 | bioRxiv | 2023 Oct 27 |
Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity. | Griffin GK, Wu J, Iracheta-Vellve A, Patti JC, Hsu J, Davis T, Dele-Oni D, Du PP, Halawi AG, Ishizuka JJ, Kim SY, Klaeger S, Knudsen NH, Miller BC, Nguyen TH, Olander KE, Papanastasiou M, Rachimi S, Robitschek EJ, Schneider EM, Yeary MD, Zimmer MD, Jaffe JD, Carr SA, Doench JG, Haining WN, Yates KB, Manguso RT, Bernstein BE | Nature | 33953401 | Nature | 2021 Jul |
Extended-representation bisulfite sequencing of gene regulatory elements in multiplexed samples and single cells. | Shareef SJ, Bevill SM, Raman AT, Aryee MJ, van Galen P, Hovestadt V, Bernstein BE | Nature biotechnology | 33958785 | Nat Biotechnol | 2021 Sep |
Orthologous CRISPR-Cas9 enzymes for combinatorial genetic screens. | Najm FJ, Strand C, Donovan KF, Hegde M, Sanson KR, Vaimberg EW, Sullender ME, Hartenian E, Kalani Z, Fusi N, Listgarten J, Younger ST, Bernstein BE, Root DE, Doench JG | Nature biotechnology | 29251726 | Nat Biotechnol | 2018 Feb |
Epigenome editing strategies for the functional annotation of CTCF insulators. | Tarjan DR, Flavahan WA, Bernstein BE | Nature communications | 31534142 | Nat Commun | 2019 Sep 18 |
Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs. | Flavahan WA, Drier Y, Johnstone SE, Hemming ML, Tarjan DR, Hegazi E, Shareef SJ, Javed NM, Raut CP, Eschle BK, Gokhale PC, Hornick JL, Sicinska ET, Demetri GD, Bernstein BE | Nature | 31666694 | Nature | 2019 Nov |
Insulator dysfunction and oncogene activation in IDH mutant gliomas. | Flavahan WA, Drier Y, Liau BB, Gillespie SM, Venteicher AS, Stemmer-Rachamimov AO, Suvà ML, Bernstein BE | Nature | 26700815 | Nature | 2016 Jan 7 |
Long-range phasing of dynamic, tissue-specific and allele-specific regulatory elements. | Battaglia S, Dong K, Wu J, Chen Z, Najm FJ, Zhang Y, Moore MM, Hecht V, Shoresh N, Bernstein BE | Nature genetics | 36195755 | Nat Genet | 2022 Oct |
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Unconventional Ways to Live and Die: Cell Death and Survival in Development, Homeostasis, and Disease. | Gudipaty SA, Conner CM, Rosenblatt J, Montell DJ | Annual review of cell and developmental biology | 30089222 | Annu Rev Cell Dev Biol | 2018 Oct 6 |
Akt1 and dCIZ1 promote cell survival from apoptotic caspase activation during regeneration and oncogenic overgrowth. | Sun G, Ding XA, Argaw Y, Guo X, Montell DJ | Nature communications | 33184261 | Nat Commun | 2020 Nov 12 |
A molecular signature for anastasis, recovery from the brink of apoptotic cell death. | Sun G, Guzman E, Balasanyan V, Conner CM, Wong K, Zhou HR, Kosik KS, Montell DJ | The Journal of cell biology | 28768686 | J Cell Biol | 2017 Oct 2 |
Coordination of two enhancers drives expression of olfactory trace amine-associated receptors. | Fei A, Wu W, Tan L, Tang C, Xu Z, Huo X, Bao H, Kong Y, Johnson M, Hartmann G, Talay M, Yang C, Riegler C, Herrera KJ, Engert F, Xie XS, Barnea G, Liberles SD, Yang H, Li Q | Nature communications | 34145235 | Nat Commun | 2021 Jun 18 |
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A Near-Complete Spatial Map of Olfactory Receptors in the Mouse Main Olfactory Epithelium. | Tan L, Xie XS | Chemical senses | 29796642 | Chem Senses | 2018 Jul 5 |
Single cell genomics to study DNA and chromosome changes in human gametes and embryos. | Blanshard RC, Chen C, Xie XS, Hoffmann ER | Methods in cell biology | 29804682 | Methods Cell Biol | 2018 |
Three-dimensional genome structures of single diploid human cells. | Tan L, Xing D, Chang CH, Li H, Xie XS | Science (New York, N.Y.) | 30166492 | Science | 2018 Aug 31 |
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Direct protein delivery to mammalian cells using cell-permeable Cys2-His2 zinc-finger domains. | Gaj T, Liu J | Journal of visualized experiments : JoVE | 25866937 | J Vis Exp | 2015 Mar 25 |
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A chemically programmed antibody is a long-lasting and potent inhibitor of influenza neuraminidase. | Hayakawa M, Toda N, Carrillo N, Thornburg NJ, Crowe JE Jr, Barbas CF 3rd | Chembiochem : a European journal of chemical biology | 22965667 | Chembiochem | 2012 Oct 15 |
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Protein delivery using Cys2-His2 zinc-finger domains. | Gaj T, Liu J, Anderson KE, Sirk SJ, Barbas CF 3rd | ACS chemical biology | 24936957 | ACS Chem Biol | 2014 Aug 15 |
Facile and stabile linkages through tyrosine: bioconjugation strategies with the tyrosine-click reaction. | Ban H, Nagano M, Gavrilyuk J, Hakamata W, Inokuma T, Barbas CF 3rd | Bioconjugate chemistry | 23534985 | Bioconjug Chem | 2013 Apr 17 |
Improving the serum stability of site-specific antibody conjugates with sulfone linkers. | Patterson JT, Asano S, Li X, Rader C, Barbas CF 3rd | Bioconjugate chemistry | 25099687 | Bioconjug Chem | 2014 Aug 20 |
N-Sulfonyl-β-lactam hapten as an effective labeling reagent for aldolase mAb. | Inokuma T, Fuller RP, Barbas CF 3rd | Bioorganic & medicinal chemistry letters | 25791455 | Bioorg Med Chem Lett | 2015 Apr 15 |
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Chimeric TALE recombinases with programmable DNA sequence specificity. | Mercer AC, Gaj T, Fuller RP, Barbas CF 3rd | Nucleic acids research | 23019222 | Nucleic Acids Res | 2012 Nov |
Directed evolution of the TALE N-terminal domain for recognition of all 5' bases. | Lamb BM, Mercer AC, Barbas CF 3rd | Nucleic acids research | 23980031 | Nucleic Acids Res | 2013 Nov |
Expanding the scope of site-specific recombinases for genetic and metabolic engineering. | Gaj T, Sirk SJ, Barbas CF 3rd | Biotechnology and bioengineering | 23982993 | Biotechnol Bioeng | 2014 Jan |
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Protein Delivery of Cell-Penetrating Zinc-Finger Activators Stimulates Latent HIV-1-Infected Cells. | Perdigão PRL, Cunha-Santos C, Barbas CF 3rd, Santa-Marta M, Goncalves J | Molecular therapy. Methods & clinical development | 32637446 | Mol Ther Methods Clin Dev | 2020 Sep 11 |
Redesigning Recombinase Specificity for Safe Harbor Sites in the Human Genome. | Wallen MC, Gaj T, Barbas CF 3rd | PloS one | 26414179 | PLoS One | 2015 |
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Magnetoelectric nanodiscs enable wireless transgene-free neuromodulation. | Kim YJ, Kent N, Vargas Paniagua E, Driscoll N, Tabet A, Koehler F, Malkin E, Frey E, Manthey M, Sahasrabudhe A, Cannon TM, Nagao K, Mankus D, Bisher M, de Nola G, Lytton-Jean A, Signorelli L, Gregurec D, Anikeeva P | Nature nanotechnology | 39394431 | Nat Nanotechnol | 2025 Jan |
Trigeminal afferents sense locomotion-related meningeal deformations. | Blaeser AS, Sugden AU, Zhao J, Carneiro-Nascimento S, Shipley FB, Carrié H, Andermann ML, Levy D | Cell reports | 36384109 | Cell Rep | 2022 Nov 15 |
Hypothalamic dopamine neurons motivate mating through persistent cAMP signalling. | Zhang SX, Lutas A, Yang S, Diaz A, Fluhr H, Nagel G, Gao S, Andermann ML | Nature | 34433964 | Nature | 2021 Sep |
Sensory cortical ensembles exhibit differential coupling to ripples in distinct hippocampal subregions. | Jeong H, Namboodiri VMK, Jung MW, Andermann ML | bioRxiv : the preprint server for biology | 36993665 | bioRxiv | 2023 Mar 18 |
Brainstem serotonin neurons selectively gate retinal information flow to thalamus. | Reggiani JDS, Jiang Q, Barbini M, Lutas A, Liang L, Fernando J, Deng F, Wan J, Li Y, Chen C, Andermann ML | Neuron | 36584680 | Neuron | 2023 Mar 1 |
Estimation of Current and Future Physiological States in Insular Cortex. | Livneh Y, Sugden AU, Madara JC, Essner RA, Flores VI, Sugden LA, Resch JM, Lowell BB, Andermann ML | Neuron | 31955944 | Neuron | 2020 Mar 18 |
A spatially-resolved transcriptional atlas of the murine dorsal pons at single-cell resolution. | Nardone S, De Luca R, Zito A, Klymko N, Nicoloutsopoulos D, Amsalem O, Brannigan C, Resch JM, Jacobs CL, Pant D, Veregge M, Srinivasan H, Grippo RM, Yang Z, Zeidel ML, Andermann ML, Harris KD, Tsai LT, Arrigoni E, Verstegen AMJ, Saper CB, Lowell BB | bioRxiv : the preprint server for biology | 38014113 | bioRxiv | 2023 Nov 17 |
A spatially-resolved transcriptional atlas of the murine dorsal pons at single-cell resolution. | Nardone S, De Luca R, Zito A, Klymko N, Nicoloutsopoulos D, Amsalem O, Brannigan C, Resch JM, Jacobs CL, Pant D, Veregge M, Srinivasan H, Grippo RM, Yang Z, Zeidel ML, Andermann ML, Harris KD, Tsai LT, Arrigoni E, Verstegen AMJ, Saper CB, Lowell BB | Nature communications | 38438345 | Nat Commun | 2024 Mar 4 |
Sensory cortical ensembles exhibit differential coupling to ripples in distinct hippocampal subregions. | Jeong H, Namboodiri VMK, Jung MW, Andermann ML | Current biology : CB | 37995696 | Curr Biol | 2023 Dec 4 |
Transient cAMP production drives rapid and sustained spiking in brainstem parabrachial neurons to suppress feeding. | Singh Alvarado J, Lutas A, Madara JC, Isaac J, Lommer C, Massengill C, Andermann ML | Neuron | 38417435 | Neuron | 2024 May 1 |
Tracking Calcium Dynamics and Immune Surveillance at the Choroid Plexus Blood-Cerebrospinal Fluid Interface. | Shipley FB, Dani N, Xu H, Deister C, Cui J, Head JP, Sadegh C, Fame RM, Shannon ML, Flores VI, Kishkovich T, Jang E, Klein EM, Goldey GJ, He K, Zhang Y, Holtzman MJ, Kirchhausen T, Wyart C, Moore CI, Andermann ML, Lehtinen MK | Neuron | 32961128 | Neuron | 2020 Nov 25 |
Choroid plexus-targeted NKCC1 overexpression to treat post-hemorrhagic hydrocephalus. | Sadegh C, Xu H, Sutin J, Fatou B, Gupta S, Pragana A, Taylor M, Kalugin PN, Zawadzki ME, Alturkistani O, Shipley FB, Dani N, Fame RM, Wurie Z, Talati P, Schleicher RL, Klein EM, Zhang Y, Holtzman MJ, Moore CI, Lin PY, Patel AB, Warf BC, Kimberly WT, Steen H, Andermann ML, Lehtinen MK | Neuron | 36893755 | Neuron | 2023 May 17 |
Repeated stress triggers seeking of a starvation-like state in anxiety-prone female mice. | Kucukdereli H, Amsalem O, Pottala T, Lim M, Potgieter L, Hasbrouck A, Lutas A, Andermann ML | Neuron | 38642553 | Neuron | 2024 Jul 3 |
Competition between stochastic neuropeptide signals calibrates the rate of satiation. | Zhang SX, Kim A, Madara JC, Zhu PK, Christenson LF, Lutas A, Kalugin PN, Jin Y, Pal A, Tian L, Lowell BB, Andermann ML | Research square | 37546985 | Res Sq | 2023 Jul 26 |
Sensitization of meningeal afferents to locomotion-related meningeal deformations in a migraine model. | Blaeser AS, Zhao J, Sugden AU, Carneiro-Nascimento S, Andermann ML, Levy D | bioRxiv : the preprint server for biology | 37577675 | bioRxiv | 2023 Nov 28 |
Sensitization of meningeal afferents to locomotion-related meningeal deformations in a migraine model. | Blaeser AS, Zhao J, Sugden AU, Carneiro-Nascimento S, Andermann ML, Levy D | eLife | 38329894 | Elife | 2024 Feb 8 |
History-dependent dopamine release increases cAMP levels in most basal amygdala glutamatergic neurons to control learning. | Lutas A, Fernando K, Zhang SX, Sambangi A, Andermann ML | Cell reports | 35081349 | Cell Rep | 2022 Jan 25 |
Visual association cortex links cues with conjunctions of reward and locomotor contexts. | McGuire KL, Amsalem O, Sugden AU, Ramesh RN, Fernando J, Burgess CR, Andermann ML | Current biology : CB | 35245458 | Curr Biol | 2022 Apr 11 |
The choroid plexus synergizes with immune cells during neuroinflammation. | Xu H, Lotfy P, Gelb S, Pragana A, Hehnly C, Byer LIJ, Shipley FB, Zawadzki ME, Cui J, Deng L, Taylor M, Webb M, Lidov HGW, Andermann ML, Chiu IM, Ordovas-Montanes J, Lehtinen MK | Cell | 39089253 | Cell | 2024 Sep 5 |
Cellular activity in insular cortex across seconds to hours: Sensations and predictions of bodily states. | Livneh Y, Andermann ML | Neuron | 34582784 | Neuron | 2021 Nov 17 |
Retinal Inputs to the Thalamus Are Selectively Gated by Arousal. | Liang L, Fratzl A, Reggiani JDS, El Mansour O, Chen C, Andermann ML | Current biology : CB | 32795442 | Curr Biol | 2020 Oct 19 |
Cortical reactivations predict future sensory responses. | Nguyen ND, Lutas A, Amsalem O, Fernando J, Ahn AY, Hakim R, Vergara J, McMahon J, Dimidschstein J, Sabatini BL, Andermann ML | Nature | 38093002 | Nature | 2024 Jan |
Applications and Comparison of Dimensionality Reduction Methods for Microbiome Data. | Armstrong G, Rahman G, Martino C, McDonald D, Gonzalez A, Mishne G, Knight R | Frontiers in bioinformatics | 36304280 | Front Bioinform | 2022 |
Development of a Rapid and Sensitive CasRx-Based Diagnostic Assay for SARS-CoV-2. | Brogan DJ, Chaverra-Rodriguez D, Lin CP, Smidler AL, Yang T, Alcantara LM, Antoshechkin I, Liu J, Raban RR, Belda-Ferre P, Knight R, Komives EA, Akbari OS | ACS sensors | 34714054 | ACS Sens | 2021 Nov 26 |
Standardized multi-omics of Earth's microbiomes reveals microbial and metabolite diversity. | Shaffer JP, Nothias LF, Thompson LR, Sanders JG, Salido RA, Couvillion SP, Brejnrod AD, Lejzerowicz F, Haiminen N, Huang S, Lutz HL, Zhu Q, Martino C, Morton JT, Karthikeyan S, Nothias-Esposito M, Dührkop K, Böcker S, Kim HW, Aksenov AA, Bittremieux W, Minich JJ, Marotz C, Bryant MM, Sanders K, Schwartz T, Humphrey G, Vásquez-Baeza Y, Tripathi A, Parida L, Carrieri AP, Beck KL, Das P, González A, McDonald D, Ladau J, Karst SM, Albertsen M, Ackermann G, DeReus J, Thomas T, Petras D, Shade A, Stegen J, Song SJ, Metz TO, Swafford AD, Dorrestein PC, Jansson JK, Gilbert JA, Knight R, Earth Microbiome Project 500 (EMP500) Consortium | Nature microbiology | 36443458 | Nat Microbiol | 2022 Dec |
Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions. | Narunsky-Haziza L, Sepich-Poore GD, Livyatan I, Asraf O, Martino C, Nejman D, Gavert N, Stajich JE, Amit G, González A, Wandro S, Perry G, Ariel R, Meltser A, Shaffer JP, Zhu Q, Balint-Lahat N, Barshack I, Dadiani M, Gal-Yam EN, Patel SP, Bashan A, Swafford AD, Pilpel Y, Knight R, Straussman R | Cell | 36179670 | Cell | 2022 Sep 29 |
SARS-CoV-2 detection status associates with bacterial community composition in patients and the hospital environment. | Marotz C, Belda-Ferre P, Ali F, Das P, Huang S, Cantrell K, Jiang L, Martino C, Diner RE, Rahman G, McDonald D, Armstrong G, Kodera S, Donato S, Ecklu-Mensah G, Gottel N, Salas Garcia MC, Chiang LY, Salido RA, Shaffer JP, Bryant MK, Sanders K, Humphrey G, Ackermann G, Haiminen N, Beck KL, Kim HC, Carrieri AP, Parida L, Vázquez-Baeza Y, Torriani FJ, Knight R, Gilbert J, Sweeney DA, Allard SM | Microbiome | 34103074 | Microbiome | 2021 Jun 8 |
Evaluating Organism-Wide Changes in the Metabolome and Microbiome following a Single Dose of Antibiotic. | Vrbanac A, Patras KA, Jarmusch AK, Mills RH, Shing SR, Quinn RA, Vargas F, Gonzalez DJ, Dorrestein PC, Knight R, Nizet V | mSystems | 33024048 | mSystems | 2020 Oct 6 |
Implementation of Practical Surface SARS-CoV-2 Surveillance in School Settings. | Cantú VJ, Belda-Ferre P, Salido RA, Tsai R, Austin B, Jordan W, Asudani M, Walster A, Magallanes CG, Valentine H, Manjoonian A, Wijaya C, Omaleki V, Sanders K, Aigner S, Baer NA, Betty M, Castro-Martínez A, Cheung W, Crescini ES, De Hoff P, Eisner E, Hakim A, Kapadia B, Lastrella AL, Lawrence ES, Ngo TT, Ostrander T, Sathe S, Seaver P, Smoot EW, Carlin AF, Yeo GW, Laurent LC, Manlutac AL, Fielding-Miller R, Knight R | mSystems | 35703437 | mSystems | 2022 Aug 30 |
Challenges in Determining the Role of Microbiome Evolution in Barrett's Esophagus and Progression to Esophageal Adenocarcinoma. | Guccione C, Yadlapati R, Shah S, Knight R, Curtius K | Microorganisms | 34683324 | Microorganisms | 2021 Sep 22 |
Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission. | Karthikeyan S, Levy JI, De Hoff P, Humphrey G, Birmingham A, Jepsen K, Farmer S, Tubb HM, Valles T, Tribelhorn CE, Tsai R, Aigner S, Sathe S, Moshiri N, Henson B, Mark AM, Hakim A, Baer NA, Barber T, Belda-Ferre P, Chacón M, Cheung W, Cresini ES, Eisner ER, Lastrella AL, Lawrence ES, Marotz CA, Ngo TT, Ostrander T, Plascencia A, Salido RA, Seaver P, Smoot EW, McDonald D, Neuhard RM, Scioscia AL, Satterlund AM, Simmons EH, Abelman DB, Brenner D, Bruner JC, Buckley A, Ellison M, Gattas J, Gonias SL, Hale M, Hawkins F, Ikeda L, Jhaveri H, Johnson T, Kellen V, Kremer B, Matthews G, McLawhon RW, Ouillet P, Park D, Pradenas A, Reed S, Riggs L, Sanders A, Sollenberger B, Song A, White B, Winbush T, Aceves CM, Anderson C, Gangavarapu K, Hufbauer E, Kurzban E, Lee J, Matteson NL, Parker E, Perkins SA, Ramesh KS, Robles-Sikisaka R, Schwab MA, Spencer E, Wohl S, Nicholson L, McHardy IH, Dimmock DP, Hobbs CA, Bakhtar O, Harding A, Mendoza A, Bolze A, Becker D, Cirulli ET, Isaksson M, Schiabor Barrett KM, Washington NL, Malone JD, Schafer AM, Gurfield N, Stous S, Fielding-Miller R, Garfein RS, Gaines T, Anderson C, Martin NK, Schooley R, Austin B, MacCannell DR, Kingsmore SF, Lee W, Shah S, McDonald E, Yu AT, Zeller M, Fisch KM, Longhurst C, Maysent P, Pride D, Khosla PK, Laurent LC, Yeo GW, Andersen KG, Knight R | Nature | 35798029 | Nature | 2022 Sep |
Enhancing untargeted metabolomics using metadata-based source annotation. | Gauglitz JM, West KA, Bittremieux W, Williams CL, Weldon KC, Panitchpakdi M, Di Ottavio F, Aceves CM, Brown E, Sikora NC, Jarmusch AK, Martino C, Tripathi A, Meehan MJ, Dorrestein K, Shaffer JP, Coras R, Vargas F, Goldasich LD, Schwartz T, Bryant M, Humphrey G, Johnson AJ, Spengler K, Belda-Ferre P, Diaz E, McDonald D, Zhu Q, Elijah EO, Wang M, Marotz C, Sprecher KE, Vargas-Robles D, Withrow D, Ackermann G, Herrera L, Bradford BJ, Marques LMM, Amaral JG, Silva RM, Veras FP, Cunha TM, Oliveira RDR, Louzada-Junior P, Mills RH, Piotrowski PK, Servetas SL, Da Silva SM, Jones CM, Lin NJ, Lippa KA, Jackson SA, Daouk RK, Galasko D, Dulai PS, Kalashnikova TI, Wittenberg C, Terkeltaub R, Doty MM, Kim JH, Rhee KE, Beauchamp-Walters J, Wright KP Jr, Dominguez-Bello MG, Manary M, Oliveira MF, Boland BS, Lopes NP, Guma M, Swafford AD, Dutton RJ, Knight R, Dorrestein PC | Nature biotechnology | 35798960 | Nat Biotechnol | 2022 Dec |
Compositionally Aware Phylogenetic Beta-Diversity Measures Better Resolve Microbiomes Associated with Phenotype. | Martino C, McDonald D, Cantrell K, Dilmore AH, Vázquez-Baeza Y, Shenhav L, Shaffer JP, Rahman G, Armstrong G, Allaband C, Song SJ, Knight R | mSystems | 35477286 | mSystems | 2022 Jun 28 |
Naturalization of the microbiota developmental trajectory of Cesarean-born neonates after vaginal seeding. | Song SJ, Wang J, Martino C, Jiang L, Thompson WK, Shenhav L, McDonald D, Marotz C, Harris PR, Hernandez CD, Henderson N, Ackley E, Nardella D, Gillihan C, Montacuti V, Schweizer W, Jay M, Combellick J, Sun H, Garcia-Mantrana I, Gil Raga F, Collado MC, Rivera-Viñas JI, Campos-Rivera M, Ruiz-Calderon JF, Knight R, Dominguez-Bello MG | Med (New York, N.Y.) | 35590169 | Med | 2021 Aug 13 |
Incomplete human reference genomes can drive false sex biases and expose patient-identifying information in metagenomic data. | Guccione C, Patel L, Tomofuji Y, McDonald D, Gonzalez A, Sepich-Poore GD, Sonehara K, Zakeri M, Chen Y, Dilmore AH, Damle N, Baranzini SE, Nakatsuji T, Gallo RL, Langmead B, Okada Y, Curtius K, Knight R | Research square | 39502785 | Res Sq | 2024 Oct 23 |
Determination of Effect Sizes for Power Analysis for Microbiome Studies Using Large Microbiome Databases. | Rahman G, McDonald D, Gonzalez A, Vázquez-Baeza Y, Jiang L, Casals-Pascual C, Hakim D, Dilmore AH, Nowinski B, Peddada S, Knight R | Genes | 37372419 | Genes (Basel) | 2023 Jun 9 |
Greengenes2 unifies microbial data in a single reference tree. | McDonald D, Jiang Y, Balaban M, Cantrell K, Zhu Q, Gonzalez A, Morton JT, Nicolaou G, Parks DH, Karst SM, Albertsen M, Hugenholtz P, DeSantis T, Song SJ, Bartko A, Havulinna AS, Jousilahti P, Cheng S, Inouye M, Niiranen T, Jain M, Salomaa V, Lahti L, Mirarab S, Knight R | Nature biotechnology | 37500913 | Nat Biotechnol | 2024 May |
microbeMASST: a taxonomically informed mass spectrometry search tool for microbial metabolomics data. | Zuffa S, Schmid R, Bauermeister A, P Gomes PW, Caraballo-Rodriguez AM, El Abiead Y, Aron AT, Gentry EC, Zemlin J, Meehan MJ, Avalon NE, Cichewicz RH, Buzun E, Terrazas MC, Hsu CY, Oles R, Ayala AV, Zhao J, Chu H, Kuijpers MCM, Jackrel SL, Tugizimana F, Nephali LP, Dubery IA, Madala NE, Moreira EA, Costa-Lotufo LV, Lopes NP, Rezende-Teixeira P, Jimenez PC, Rimal B, Patterson AD, Traxler MF, Pessotti RC, Alvarado-Villalobos D, Tamayo-Castillo G, Chaverri P, Escudero-Leyva E, Quiros-Guerrero LM, Bory AJ, Joubert J, Rutz A, Wolfender JL, Allard PM, Sichert A, Pontrelli S, Pullman BS, Bandeira N, Gerwick WH, Gindro K, Massana-Codina J, Wagner BC, Forchhammer K, Petras D, Aiosa N, Garg N, Liebeke M, Bourceau P, Kang KB, Gadhavi H, de Carvalho LPS, Silva Dos Santos M, Pérez-Lorente AI, Molina-Santiago C, Romero D, Franke R, Brönstrup M, Vera Ponce de León A, Pope PB, La Rosa SL, La Barbera G, Roager HM, Laursen MF, Hammerle F, Siewert B, Peintner U, Licona-Cassani C, Rodriguez-Orduña L, Rampler E, Hildebrand F, Koellensperger G, Schoeny H, Hohenwallner K, Panzenboeck L, Gregor R, O'Neill EC, Roxborough ET, Odoi J, Bale NJ, Ding S, Sinninghe Damsté JS, Guan XL, Cui JJ, Ju KS, Silva DB, Silva FMR, da Silva GF, Koolen HHF, Grundmann C, Clement JA, Mohimani H, Broders K, McPhail KL, Ober-Singleton SE, Rath CM, McDonald D, Knight R, Wang M, Dorrestein PC | Nature microbiology | 38316926 | Nat Microbiol | 2024 Feb |
A comparison of DNA/RNA extraction protocols for high-throughput sequencing of microbial communities. | Shaffer JP, Marotz C, Belda-Ferre P, Martino C, Wandro S, Estaki M, Salido RA, Carpenter CS, Zaramela LS, Minich JJ, Bryant M, Sanders K, Fraraccio S, Ackermann G, Humphrey G, Swafford AD, Miller-Montgomery S, Knight R | BioTechniques | 33512248 | Biotechniques | 2021 Mar |
Host variables confound gut microbiota studies of human disease. | Vujkovic-Cvijin I, Sklar J, Jiang L, Natarajan L, Knight R, Belkaid Y | Nature | 33149306 | Nature | 2020 Nov |
Candidate probiotic Lactiplantibacillus plantarum HNU082 rapidly and convergently evolves within human, mice, and zebrafish gut but differentially influences the resident microbiome. | Huang S, Jiang S, Huo D, Allaband C, Estaki M, Cantu V, Belda-Ferre P, Vázquez-Baeza Y, Zhu Q, Ma C, Li C, Zarrinpar A, Liu YY, Knight R, Zhang J | Microbiome | 34193290 | Microbiome | 2021 Jun 30 |
Microbial context predicts SARS-CoV-2 prevalence in patients and the hospital built environment. | Marotz C, Belda-Ferre P, Ali F, Das P, Huang S, Cantrell K, Jiang L, Martino C, Diner RE, Rahman G, McDonald D, Armstrong G, Kodera S, Donato S, Ecklu-Mensah G, Gottel N, Garcia MCS, Chiang LY, Salido RA, Shaffer JP, Bryant M, Sanders K, Humphrey G, Ackermann G, Haiminen N, Beck KL, Kim HC, Carrieri AP, Parida L, Vázquez-Baeza Y, Torriani FJ, Knight R, Gilbert JA, Sweeney DA, Allard SM | medRxiv : the preprint server for health sciences | 33236030 | medRxiv | 2020 Nov 22 |
Paired microbiome and metabolome analyses associate bile acid changes with colorectal cancer progression. | Fu T, Huan T, Rahman G, Zhi H, Xu Z, Oh TG, Guo J, Coulter S, Tripathi A, Martino C, McCarville JL, Zhu Q, Cayabyab F, Low B, He M, Xing S, Vargas F, Yu RT, Atkins A, Liddle C, Ayres J, Raffatellu M, Dorrestein PC, Downes M, Knight R, Evans RM | Cell reports | 37611587 | Cell Rep | 2023 Aug 29 |
Global chemical effects of the microbiome include new bile-acid conjugations. | Quinn RA, Melnik AV, Vrbanac A, Fu T, Patras KA, Christy MP, Bodai Z, Belda-Ferre P, Tripathi A, Chung LK, Downes M, Welch RD, Quinn M, Humphrey G, Panitchpakdi M, Weldon KC, Aksenov A, da Silva R, Avila-Pacheco J, Clish C, Bae S, Mallick H, Franzosa EA, Lloyd-Price J, Bussell R, Thron T, Nelson AT, Wang M, Leszczynski E, Vargas F, Gauglitz JM, Meehan MJ, Gentry E, Arthur TD, Komor AC, Poulsen O, Boland BS, Chang JT, Sandborn WJ, Lim M, Garg N, Lumeng JC, Xavier RJ, Kazmierczak BI, Jain R, Egan M, Rhee KE, Ferguson D, Raffatellu M, Vlamakis H, Haddad GG, Siegel D, Huttenhower C, Mazmanian SK, Evans RM, Nizet V, Knight R, Dorrestein PC | Nature | 32103176 | Nature | 2020 Mar |
A comparison of six DNA extraction protocols for 16S, ITS and shotgun metagenomic sequencing of microbial communities. | Shaffer JP, Carpenter CS, Martino C, Salido RA, Minich JJ, Bryant M, Sanders K, Schwartz T, Humphrey G, Swafford AD, Knight R | BioTechniques | 35713407 | Biotechniques | 2022 Jun |
A Sensitive, Rapid, and Portable CasRx-based Diagnostic Assay for SARS-CoV-2. | Brogan DJ, Chaverra-Rodriguez D, Lin CP, Smidler AL, Yang T, Alcantara LM, Antoshechkin I, Liu J, Raban RR, Belda-Ferre P, Knight R, Komives EA, Akbari OS | medRxiv : the preprint server for health sciences | 33106816 | medRxiv | 2020 Oct 20 |
Context-aware dimensionality reduction deconvolutes gut microbial community dynamics. | Martino C, Shenhav L, Marotz CA, Armstrong G, McDonald D, Vázquez-Baeza Y, Morton JT, Jiang L, Dominguez-Bello MG, Swafford AD, Halperin E, Knight R | Nature biotechnology | 32868914 | Nat Biotechnol | 2021 Feb |
SARS-CoV-2 Distribution in Residential Housing Suggests Contact Deposition and Correlates with Rothia sp. | Cantú VJ, Salido RA, Huang S, Rahman G, Tsai R, Valentine H, Magallanes CG, Aigner S, Baer NA, Barber T, Belda-Ferre P, Betty M, Bryant M, Casas Maya M, Castro-Martínez A, Chacón M, Cheung W, Crescini ES, De Hoff P, Eisner E, Farmer S, Hakim A, Kohn L, Lastrella AL, Lawrence ES, Morgan SC, Ngo TT, Nouri A, Plascencia A, Ruiz CA, Sathe S, Seaver P, Shwartz T, Smoot EW, Ostrander RT, Valles T, Yeo GW, Laurent LC, Fielding-Miller R, Knight R | mSystems | 35575492 | mSystems | 2022 Jun 28 |
Robustness of cancer microbiome signals over a broad range of methodological variation. | Sepich-Poore GD, McDonald D, Kopylova E, Guccione C, Zhu Q, Austin G, Carpenter C, Fraraccio S, Wandro S, Kosciolek T, Janssen S, Metcalf JL, Song SJ, Kanbar J, Miller-Montgomery S, Heaton R, Mckay R, Patel SP, Swafford AD, Korem T, Knight R | Oncogene | 38396294 | Oncogene | 2024 Apr |
TEMPTED: time-informed dimensionality reduction for longitudinal microbiome studies. | Shi P, Martino C, Han R, Janssen S, Buck G, Serrano M, Owzar K, Knight R, Shenhav L, Zhang AR | Genome biology | 39696594 | Genome Biol | 2024 Dec 19 |
Bacterial modification of the host glycosaminoglycan heparan sulfate modulates SARS-CoV-2 infectivity. | Martino C, Kellman BP, Sandoval DR, Clausen TM, Marotz CA, Song SJ, Wandro S, Zaramela LS, Salido Benítez RA, Zhu Q, Armingol E, Vázquez-Baeza Y, McDonald D, Sorrentino JT, Taylor B, Belda-Ferre P, Liang C, Zhang Y, Schifanella L, Klatt NR, Havulinna AS, Jousilahti P, Huang S, Haiminen N, Parida L, Kim HC, Swafford AD, Zengler K, Cheng S, Inouye M, Niiranen T, Jain M, Salomaa V, Esko JD, Lewis NE, Knight R | bioRxiv : the preprint server for biology | 32839779 | bioRxiv | 2020 Aug 18 |
Optimizing UniFrac with OpenACC Yields Greater Than One Thousand Times Speed Increase. | Sfiligoi I, Armstrong G, Gonzalez A, McDonald D, Knight R | mSystems | 35638356 | mSystems | 2022 Jun 28 |
Cancer's second genome: Microbial cancer diagnostics and redefining clonal evolution as a multispecies process: Humans and their tumors are not aseptic, and the multispecies nature of cancer modulates clinical care and clonal evolution: Humans and their tumors are not aseptic, and the multispecies nature of cancer modulates clinical care and clonal evolution. | Sepich-Poore GD, Guccione C, Laplane L, Pradeu T, Curtius K, Knight R | BioEssays : news and reviews in molecular, cellular and developmental biology | 35253252 | Bioessays | 2022 May |
Chemically informed analyses of metabolomics mass spectrometry data with Qemistree. | Tripathi A, Vázquez-Baeza Y, Gauglitz JM, Wang M, Dührkop K, Nothias-Esposito M, Acharya DD, Ernst M, van der Hooft JJJ, Zhu Q, McDonald D, Brejnrod AD, Gonzalez A, Handelsman J, Fleischauer M, Ludwig M, Böcker S, Nothias LF, Knight R, Dorrestein PC | Nature chemical biology | 33199911 | Nat Chem Biol | 2021 Feb |
The Gut Microbial Bile Acid Modulation and Its Relevance to Digestive Health and Diseases. | Fogelson KA, Dorrestein PC, Zarrinpar A, Knight R | Gastroenterology | 36841488 | Gastroenterology | 2023 Jun |
Phylogeny-Aware Analysis of Metagenome Community Ecology Based on Matched Reference Genomes while Bypassing Taxonomy. | Zhu Q, Huang S, Gonzalez A, McGrath I, McDonald D, Haiminen N, Armstrong G, Vázquez-Baeza Y, Yu J, Kuczynski J, Sepich-Poore GD, Swafford AD, Das P, Shaffer JP, Lejzerowicz F, Belda-Ferre P, Havulinna AS, Méric G, Niiranen T, Lahti L, Salomaa V, Kim HC, Jain M, Inouye M, Gilbert JA, Knight R | mSystems | 35369727 | mSystems | 2022 Apr 26 |
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Age-dependent immune and lymphatic responses after spinal cord injury. | Salvador AFM, Dykstra T, Rustenhoven J, Gao W, Blackburn SM, Bhasiin K, Dong MQ, Guimarães RM, Gonuguntla S, Smirnov I, Kipnis J, Herz J | Neuron | 37148871 | Neuron | 2023 Jul 19 |
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Bacteroides thetaiotaomicron-Infecting Bacteriophage Isolates Inform Sequence-Based Host Range Predictions. | Hryckowian AJ, Merrill BD, Porter NT, Van Treuren W, Nelson EJ, Garlena RA, Russell DA, Martens EC, Sonnenburg JL | Cell host & microbe | 32652063 | Cell Host Microbe | 2020 Sep 9 |
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An airway-to-brain sensory pathway mediates influenza-induced sickness. | Bin NR, Prescott SL, Horio N, Wang Y, Chiu IM, Liberles SD | Nature | 36890237 | Nature | 2023 Mar |
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De novo production of the key branch point benzylisoquinoline alkaloid reticuline in yeast. | Trenchard IJ, Siddiqui MS, Thodey K, Smolke CD | Metabolic engineering | 26166409 | Metab Eng | 2015 Sep |
Kinetic and equilibrium binding characterization of aptamers to small molecules using a label-free, sensitive, and scalable platform. | Chang AL, McKeague M, Liang JC, Smolke CD | Analytical chemistry | 24548121 | Anal Chem | 2014 Apr 1 |
Molecular tools for chemical biotechnology. | Galanie S, Siddiqui MS, Smolke CD | Current opinion in biotechnology | 23528237 | Curr Opin Biotechnol | 2013 Dec |
In Vitro Screening and in Silico Modeling of RNA-Based Gene Expression Control. | McKeague M, Wang YH, Smolke CD | ACS chemical biology | 26359915 | ACS Chem Biol | 2015 Nov 20 |
Optimization of yeast-based production of medicinal protoberberine alkaloids. | Galanie S, Smolke CD | Microbial cell factories | 26376732 | Microb Cell Fact | 2015 Sep 16 |
Protein-responsive ribozyme switches in eukaryotic cells. | Kennedy AB, Vowles JV, d'Espaux L, Smolke CD | Nucleic acids research | 25274734 | Nucleic Acids Res | 2014 Oct 29 |
Complete biosynthesis of opioids in yeast. | Galanie S, Thodey K, Trenchard IJ, Filsinger Interrante M, Smolke CD | Science (New York, N.Y.) | 26272907 | Science | 2015 Sep 4 |
Synthetic biology: advancing the design of diverse genetic systems. | Wang YH, Wei KY, Smolke CD | Annual review of chemical and biomolecular engineering | 23413816 | Annu Rev Chem Biomol Eng | 2013 |
Synthetic biology strategies for microbial biosynthesis of plant natural products. | Cravens A, Payne J, Smolke CD | Nature communications | 31086174 | Nat Commun | 2019 May 13 |
Realizing the potential of synthetic biology. | Church GM, Elowitz MB, Smolke CD, Voigt CA, Weiss R | Nature reviews. Molecular cell biology | 24622617 | Nat Rev Mol Cell Biol | 2014 Apr |
Synthetic RNA switches for yeast metabolic engineering: screening recombinant enzyme libraries. | Michener JK, Smolke CD | Methods in molecular biology (Clifton, N.J.) | 24744030 | Methods Mol Biol | 2014 |
High-throughput cellular RNA device engineering. | Townshend B, Kennedy AB, Xiang JS, Smolke CD | Nature methods | 26258292 | Nat Methods | 2015 Oct |
Engineering biosynthesis of the anticancer alkaloid noscapine in yeast. | Li Y, Smolke CD | Nature communications | 27378283 | Nat Commun | 2016 Jul 5 |
A computational workflow for the expansion of heterologous biosynthetic pathways to natural product derivatives. | Hafner J, Payne J, MohammadiPeyhani H, Hatzimanikatis V, Smolke C | Nature communications | 33741955 | Nat Commun | 2021 Mar 19 |
Engineering cellular metabolite transport for biosynthesis of computationally predicted tropane alkaloid derivatives in yeast. | Srinivasan P, Smolke CD | Proceedings of the National Academy of Sciences of the United States of America | 34140414 | Proc Natl Acad Sci U S A | 2021 Jun 22 |
Biosynthesis of medicinal tropane alkaloids in yeast. | Srinivasan P, Smolke CD | Nature | 32879484 | Nature | 2020 Sep |
A microbial biomanufacturing platform for natural and semisynthetic opioids. | Thodey K, Galanie S, Smolke CD | Nature chemical biology | 25151135 | Nat Chem Biol | 2014 Oct |
Design and Construction of Generalizable RNA-Protein Hybrid Controllers by Level-Matched Genetic Signal Amplification. | Wang YH, McKeague M, Hsu TM, Smolke CD | Cell systems | 27840078 | Cell Syst | 2016 Dec 21 |
Polymerase-guided base editing enables in vivo mutagenesis and rapid protein engineering. | Cravens A, Jamil OK, Kong D, Sockolosky JT, Smolke CD | Nature communications | 33707425 | Nat Commun | 2021 Mar 11 |
Elucidation of tropane alkaloid biosynthesis in Erythroxylum coca using a microbial pathway discovery platform. | Chavez BG, Srinivasan P, Glockzin K, Kim N, Montero Estrada O, Jirschitzka J, Rowden G, Shao J, Meinhardt L, Smolke CD, D'Auria JC | Proceedings of the National Academy of Sciences of the United States of America | 36442128 | Proc Natl Acad Sci U S A | 2022 Dec 6 |
Defining Resistance and Tolerance to Cancer. | Dillman AR, Schneider DS | Cell reports | 26565901 | Cell Rep | 2015 Nov 3 |
Predicting position along a looping immune response trajectory. | Rath P, Allen JA, Schneider DS | PloS one | 30296270 | PLoS One | 2018 |
How Many Parameters Does It Take to Describe Disease Tolerance? | Louie A, Song KH, Hotson A, Thomas Tate A, Schneider DS | PLoS biology | 27088212 | PLoS Biol | 2016 Apr |
Tracking Resilience to Infections by Mapping Disease Space. | Torres BY, Oliveira JH, Thomas Tate A, Rath P, Cumnock K, Schneider DS | PLoS biology | 27088359 | PLoS Biol | 2016 Apr |
Metabolic profiling during malaria reveals the role of the aryl hydrocarbon receptor in regulating kidney injury. | Lissner MM, Cumnock K, Davis NM, Vilches-Moure JG, Basak P, Navarrete DJ, Allen JA, Schneider D | eLife | 33021470 | Elife | 2020 Oct 6 |
Listeria monocytogenes infection causes metabolic shifts in Drosophila melanogaster. | Chambers MC, Song KH, Schneider DS | PloS one | 23272066 | PLoS One | 2012 |
Drosophila melanogaster Natural Variation Affects Growth Dynamics of Infecting Listeria monocytogenes. | Hotson AG, Schneider DS | G3 (Bethesda, Md.) | 26438294 | G3 (Bethesda) | 2015 Oct 4 |
Host Energy Source Is Important for Disease Tolerance to Malaria. | Cumnock K, Gupta AS, Lissner M, Chevee V, Davis NM, Schneider DS | Current biology : CB | 29754902 | Curr Biol | 2018 May 21 |
Interleukin 17 and senescent cells regulate the foreign body response to synthetic material implants in mice and humans. | Chung L, Maestas DR Jr, Lebid A, Mageau A, Rosson GD, Wu X, Wolf MT, Tam AJ, Vanderzee I, Wang X, Andorko JI, Zhang H, Narain R, Sadtler K, Fan H, Čiháková D, Le Saux CJ, Housseau F, Pardoll DM, Elisseeff JH | Science translational medicine | 32295900 | Sci Transl Med | 2020 Apr 15 |
The Immune System and Its Contribution to Variability in Regenerative Medicine. | Moore EM, Maestas DR Jr, Comeau HY, Elisseeff JH | Tissue engineering. Part B, Reviews | 32635878 | Tissue Eng Part B Rev | 2021 Feb |
Computational reconstruction of the signalling networks surrounding implanted biomaterials from single-cell transcriptomics. | Cherry C, Maestas DR, Han J, Andorko JI, Cahan P, Fertig EJ, Garmire LX, Elisseeff JH | Nature biomedical engineering | 34341534 | Nat Biomed Eng | 2021 Oct |
Transfer learning in a biomaterial fibrosis model identifies in vivo senescence heterogeneity and contributions to vascularization and matrix production across species and diverse pathologies. | Cherry C, Andorko JI, Krishnan K, Mejías JC, Nguyen HH, Stivers KB, Gray-Gaillard EF, Ruta A, Han J, Hamada N, Hamada M, Sturmlechner I, Trewartha S, Michel JH, Davenport Huyer L, Wolf MT, Tam AJ, Peña AN, Keerthivasan S, Le Saux CJ, Fertig EJ, Baker DJ, Housseau F, van Deursen JM, Pardoll DM, Elisseeff JH | GeroScience | 37079217 | Geroscience | 2023 Aug |
Immune and Genome Engineering as the Future of Transplantable Tissue. | Elisseeff J, Badylak SF, Boeke JD | The New England journal of medicine | 34936741 | N Engl J Med | 2021 Dec 23 |
Design of cell-type-specific hyperstable IL-4 mimetics via modular de novo scaffolds. | Yang H, Ulge UY, Quijano-Rubio A, Bernstein ZJ, Maestas DR, Chun JH, Wang W, Lin JX, Jude KM, Singh S, Orcutt-Jahns BT, Li P, Mou J, Chung L, Kuo YH, Ali YH, Meyer AS, Grayson WL, Heller NM, Garcia KC, Leonard WJ, Silva DA, Elisseeff JH, Baker D, Spangler JB | Nature chemical biology | 37024727 | Nat Chem Biol | 2023 Sep |
Transcriptomic analysis of skeletal muscle regeneration across mouse lifespan identifies altered stem cell states. | Walter LD, Orton JL, Ntekas I, Fong EHH, Maymi VI, Rudd BD, De Vlaminck I, Elisseeff JH, Cosgrove BD | Nature aging | 39578558 | Nat Aging | 2024 Dec |
Immunoengineering Biomaterials for Musculoskeletal Tissue Repair across Lifespan. | Han J, Rindone AN, Elisseeff JH | Advanced materials (Deerfield Beach, Fla.) | 38416061 | Adv Mater | 2024 Jul |
Single-cell transcriptomic analysis of skeletal muscle regeneration across mouse lifespan identifies altered stem cell states associated with senescence. | Walter LD, Orton JL, Hannah Fong EH, Maymi VI, Rudd BD, Elisseeff JH, Cosgrove BD | bioRxiv : the preprint server for biology | 37292698 | bioRxiv | 2023 May 26 |
Sirolimus-eluting airway stent reduces profibrotic Th17 cells and inhibits laryngotracheal stenosis. | Motz KM, Lina IA, Samad I, Murphy MK, Duvvuri M, Davis RJ, Gelbard A, Chung L, Chan-Li Y, Collins S, Powell JD, Elisseeff JH, Horton MR, Hillel AT | JCI insight | 37159282 | JCI Insight | 2023 Jun 8 |
Helminth egg derivatives as proregenerative immunotherapies. | Maestas DR Jr, Chung L, Han J, Wang X, Sommerfeld SD, Kelly SH, Moore E, Nguyen HH, Mejías JC, Peña AN, Zhang H, Hooks JST, Chin AF, Andorko JI, Berlinicke CA, Krishnan K, Choi Y, Anderson AE, Mahatme R, Mejia C, Eric M, Woo J, Ganguly S, Zack DJ, Zhao L, Pearce EJ, Housseau F, Pardoll DM, Elisseeff JH | Proceedings of the National Academy of Sciences of the United States of America | 36780522 | Proc Natl Acad Sci U S A | 2023 Feb 21 |
Interleukin-36γ-producing macrophages drive IL-17-mediated fibrosis. | Sommerfeld SD, Cherry C, Schwab RM, Chung L, Maestas DR Jr, Laffont P, Stein JE, Tam A, Ganguly S, Housseau F, Taube JM, Pardoll DM, Cahan P, Elisseeff JH | Science immunology | 31604843 | Sci Immunol | 2019 Oct 11 |
Senescent cells in tissue engineering. | Chin AF, Elisseeff JH | Current opinion in biotechnology | 35660479 | Curr Opin Biotechnol | 2022 Aug |
IL-17 and immunologically induced senescence regulate response to injury in osteoarthritis. | Faust HJ, Zhang H, Han J, Wolf MT, Jeon OH, Sadtler K, Peña AN, Chung L, Maestas DR Jr, Tam AJ, Pardoll DM, Campisi J, Housseau F, Zhou D, Bingham CO 3rd, Elisseeff JH | The Journal of clinical investigation | 32955487 | J Clin Invest | 2020 Oct 1 |
Biomaterials-based immunomodulation enhances survival of murine vascularized composite allografts. | Sommerfeld SD, Zhou X, Mejías JC, Oh BC, Maestas DR Jr, Furtmüller GJ, Laffont PA, Elisseeff JH, Brandacher G | Biomaterials science | 37129566 | Biomater Sci | 2023 May 30 |
Biomaterials direct functional B cell response in a material-specific manner. | Moore EM, Maestas DR Jr, Cherry CC, Garcia JA, Comeau HY, Davenport Huyer L, Kelly SH, Peña AN, Blosser RL, Rosson GD, Elisseeff JH | Science advances | 34851674 | Sci Adv | 2021 Dec 3 |
Autologous Protein Solution processing alters lymphoid and myeloid cell populations and modulates gene expression dependent on cell type. | Peña AN, Sommerfeld SD, Anderson AE, Han J, Maestas DR Jr, Mejias JC, Woodell-May J, King W, Ganguly S, Elisseeff JH | Arthritis research & therapy | 36096945 | Arthritis Res Ther | 2022 Sep 12 |
The past, present and future of ligament regenerative engineering. | Mengsteab PY, Nair LS, Laurencin CT | Regenerative medicine | 27879170 | Regen Med | 2016 Dec |
Identification of Heparan-Sulfate Rich Cells in the Loose Connective Tissues of the Axolotl (Ambystoma mexicanum) with the Potential to Mediate Growth Factor Signaling during Regeneration. | Otsuka T, Phan AQ, Laurencin CT, Esko JD, Bryant SV, Gardiner DM | Regenerative engineering and translational medicine | 33748405 | Regen Eng Transl Med | 2020 Mar |
Biomedical applications of polyphosphazenes. | Ogueri KS, Ogueri KS, Ude CC, Allcock HR, Laurencin CT | Medical devices & sensors | 33889811 | Med Devices Sens | 2020 Dec |
The Treatment of Muscle Atrophy after Rotator Cuff Tears Using Electroconductive Nanofibrous Matrices. | Tang X, Shemshaki NS, Vernekar VN, Prabhath A, Kuyinu E, Kan HM, Barajaa M, Khan Y, Laurencin CT | Regenerative engineering and translational medicine | 33816776 | Regen Eng Transl Med | 2021 Mar |
Regulation of regeneration by Heparan Sulfate Proteoglycans in the Extracellular Matrix. | Gardiner DM | Regenerative engineering and translational medicine | 29242821 | Regen Eng Transl Med | 2017 Sep |
Engineered stem cell niche matrices for rotator cuff tendon regenerative engineering. | Peach MS, Ramos DM, James R, Morozowich NL, Mazzocca AD, Doty SB, Allcock HR, Kumbar SG, Laurencin CT | PloS one | 28369135 | PLoS One | 2017 |
Regenerative engineering of long bones using the small molecule forskolin. | Awale GM, Barajaa MA, Kan HM, Seyedsalehi A, Nam GH, Hosseini FS, Ude CC, Schmidt TA, Lo KW, Laurencin CT | Proceedings of the National Academy of Sciences of the United States of America | 37216527 | Proc Natl Acad Sci U S A | 2023 May 30 |
Stromal Vascular Fraction for Osteoarthritis of the Knee Regenerative Engineering. | Ude CC, Shah S, Ogueri KS, Nair LS, Laurencin CT | Regenerative engineering and translational medicine | 35958164 | Regen Eng Transl Med | 2022 Jun |
Polyphosphazene polymers: The next generation of biomaterials for regenerative engineering and therapeutic drug delivery. | Ogueri KS, Ogueri KS, Allcock HR, Laurencin CT | Journal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B | 32309041 | J Vac Sci Technol B Nanotechnol Microelectron | 2020 May |
Poly (lactic acid)-based biomaterials for orthopaedic regenerative engineering. | Narayanan G, Vernekar VN, Kuyinu EL, Laurencin CT | Advanced drug delivery reviews | 27125191 | Adv Drug Deliv Rev | 2016 Dec 15 |
Efficacy of a Novel Electroconductive Matrix To Treat Muscle Atrophy and Fat Accumulation in Chronic Massive Rotator Cuff Tears of the Shoulder. | Shemshaki NS, Kan HM, Barajaa MA, Lebaschi A, Otsuka T, Mishra N, Nair LS, Laurencin CT | ACS biomaterials science & engineering | 37769114 | ACS Biomater Sci Eng | 2023 Oct 9 |
Fibroblast growth factor 8b (FGF-8b) enhances myogenesis and inhibits adipogenesis in rotator cuff muscle cell populations in vitro. | Otsuka T, Kan HM, Mengsteab PY, Tyson B, Laurencin CT | Proceedings of the National Academy of Sciences of the United States of America | 38147545 | Proc Natl Acad Sci U S A | 2024 Jan 2 |
Biomimetic electroconductive nanofibrous matrices for skeletal muscle regenerative engineering. | Tang X, Saveh-Shemshaki N, Kan HM, Khan Y, Laurencin CT | Regenerative engineering and translational medicine | 33426269 | Regen Eng Transl Med | 2020 Jun |
Spatial alignment of 3D printed scaffolds modulates genotypic expression in pre-osteoblasts. | Nagiah N, Bhattacharjee M, Murdock CJ, Kan HM, Barajaa M, Laurencin CT | Materials letters | 32773913 | Mater Lett | 2020 Oct 1 |
Regenerative Cell-Based Therapies: Cutting Edge, Bleeding Edge, and Off the Edge. | Laurencin CT, McClinton A | Regenerative engineering and translational medicine | 33344756 | Regen Eng Transl Med | 2020 Mar |
Animal models of osteoarthritis: classification, update, and measurement of outcomes. | Kuyinu EL, Narayanan G, Nair LS, Laurencin CT | Journal of orthopaedic surgery and research | 26837951 | J Orthop Surg Res | 2016 Feb 2 |
Biodegradable Polyphosphazene-Based Blends for Regenerative Engineering. | Ogueri KS, Escobar Ivirico JL, Nair LS, Allcock HR, Laurencin CT | Regenerative engineering and translational medicine | 28596987 | Regen Eng Transl Med | 2017 Mar |
The Axolotl Limb Regeneration Model as a Discovery Tool for Engineering the Stem Cell Niche. | Seyedhassantehrani N, Otsuka T, Singh S, Gardiner DM | Current stem cell reports | 29230380 | Curr Stem Cell Rep | 2017 Sep |
Regenerative Engineering of Cartilage Using Adipose-Derived Stem Cells. | Kasir R, Vernekar VN, Laurencin CT | Regenerative engineering and translational medicine | 26998511 | Regen Eng Transl Med | 2015 Dec 1 |
Nanofiber technology: its transformative role in nanomedicine. | James R, Laurencin CT | Nanomedicine (London, England) | 27246812 | Nanomedicine (Lond) | 2016 Jun |
Development of Tripolymeric Triaxial Electrospun Fibrous Matrices for Dual Drug Delivery Applications. | Nagiah N, Murdock CJ, Bhattacharjee M, Nair L, Laurencin CT | Scientific reports | 31953439 | Sci Rep | 2020 Jan 17 |
Nail matrix regenerative engineering: in vitro evaluation of poly(lactide-co-glycolide)/gelatin fibrous substrates. | Montgomery AB, McClinton A, Nair L, Laurencin CT | Journal of biomedical materials research. Part A | 31981298 | J Biomed Mater Res A | 2020 May |
Regenerative engineered vascularized bone mediated by calcium peroxide. | Daneshmandi L, Laurencin CT | Journal of biomedical materials research. Part A | 31925886 | J Biomed Mater Res A | 2020 May |
Generational Biodegradable and Regenerative Polyphosphazene Polymers and their Blends with Poly (lactic-co-glycolic acid). | Ogueri KS, Allcock HR, Laurencin CT | Progress in polymer science | 31551636 | Prog Polym Sci | 2019 Nov |
Emergence of the Stem Cell Secretome in Regenerative Engineering. | Daneshmandi L, Shah S, Jafari T, Bhattacharjee M, Momah D, Saveh-Shemshaki N, Lo KW, Laurencin CT | Trends in biotechnology | 32622558 | Trends Biotechnol | 2020 Dec |
Synthesis, Physicochemical Analysis, and Side Group Optimization of Degradable Dipeptide-Based Polyphosphazenes as Potential Regenerative Biomaterials. | Ogueri KS, Escobar Ivirico JL, Li Z, Blumenfield RH, Allcock HR, Laurencin CT | ACS applied polymer materials | 32699835 | ACS Appl Polym Mater | 2019 Jun 14 |
Skeletal Muscle Regenerative Engineering. | Tang X, Daneshmandi L, Awale G, Nair LS, Laurencin CT | Regenerative engineering and translational medicine | 33778155 | Regen Eng Transl Med | 2019 Sep |
Control of mesenchymal cell fate via application of FGF-8b in vitro. | Otsuka T, Mengsteab PY, Laurencin CT | Stem cell research | 33445073 | Stem Cell Res | 2021 Mar |
Muscle degeneration in chronic massive rotator cuff tears of the shoulder: Addressing the real problem using a graphene matrix. | Saveh Shemshaki N, Kan HM, Barajaa M, Otsuka T, Lebaschi A, Mishra N, Nair LS, Laurencin CT | Proceedings of the National Academy of Sciences of the United States of America | 35939692 | Proc Natl Acad Sci U S A | 2022 Aug 16 |
Regenerative engineering: a review of recent advances and future directions. | Esdaille CJ, Washington KS, Laurencin CT | Regenerative medicine | 34030463 | Regen Med | 2021 May |
Bioinspired Scaffold Designs for Regenerating Musculoskeletal Tissue Interfaces. | Barajaa MA, Nair LS, Laurencin CT | Regenerative engineering and translational medicine | 33344758 | Regen Eng Transl Med | 2020 Dec |
Mechanically superior matrices promote osteointegration and regeneration of anterior cruciate ligament tissue in rabbits. | Mengsteab PY, Otsuka T, McClinton A, Shemshaki NS, Shah S, Kan HM, Obopilwe E, Vella AT, Nair LS, Laurencin CT | Proceedings of the National Academy of Sciences of the United States of America | 33144508 | Proc Natl Acad Sci U S A | 2020 Nov 17 |
The Mechanism of Metallosis After Total Hip Arthroplasty. | Ude CC, Esdaille CJ, Ogueri KS, Ho-Man K, Laurencin SJ, Nair LS, Laurencin CT | Regenerative engineering and translational medicine | 35530571 | Regen Eng Transl Med | 2021 Sep |
Injectable amnion hydrogel-mediated delivery of adipose-derived stem cells for osteoarthritis treatment. | Bhattacharjee M, Escobar Ivirico JL, Kan HM, Shah S, Otsuka T, Bordett R, Barajaa M, Nagiah N, Pandey R, Nair LS, Laurencin CT | Proceedings of the National Academy of Sciences of the United States of America | 35046053 | Proc Natl Acad Sci U S A | 2022 Jan 25 |
Addressing Justified Vaccine Hesitancy in the Black Community. | Laurencin CT | Journal of racial and ethnic health disparities | 33783755 | J Racial Ethn Health Disparities | 2021 Jun |
Inductive Materials for Regenerative Engineering. | Hosseini FS, Nair LS, Laurencin CT | Journal of dental research | 33906507 | J Dent Res | 2021 Sep |
Hyaluronic acid-British anti-Lewisite as a safer chelation therapy for the treatment of arthroplasty-related metallosis. | Ude CC, Schmidt SJ, Laurencin S, Shah S, Esdaille J, Kan HM, Holt BD, Arnold AM, Wolf ME, Nair LS, Sydlik SA, Laurencin CT | Proceedings of the National Academy of Sciences of the United States of America | 37903261 | Proc Natl Acad Sci U S A | 2023 Nov 7 |
The Quest toward limb regeneration: a regenerative engineering approach. | Laurencin CT, Nair LS | Regenerative biomaterials | 27047679 | Regen Biomater | 2016 Jun |
Harnessing cAMP signaling in musculoskeletal regenerative engineering. | Ifegwu OC, Awale G, Rajpura K, Lo KW, Laurencin CT | Drug discovery today | 28359841 | Drug Discov Today | 2017 Jul |
An American Crisis: the Lack of Black Men in Medicine. | Laurencin CT, Murray M | Journal of racial and ethnic health disparities | 28534304 | J Racial Ethn Health Disparities | 2017 Jun |
REGENERATIVE ENGINEERING: APPROACHES TO LIMB REGENERATION AND OTHER GRAND CHALLENGES. | Laurencin CT, Nair LS | Regenerative engineering and translational medicine | 26985451 | Regen Eng Transl Med | 2015 Apr 1 |
Corrosion of Metals During Use in Arthroplasty. | Ude CC, Dzidotor GK, Iloeje K, Nair LS, Laurencin CT | ACS applied bio materials | 37261398 | ACS Appl Bio Mater | 2023 Jun 19 |
Growth factor delivery strategies for rotator cuff repair and regeneration. | Prabhath A, Vernekar VN, Sanchez E, Laurencin CT | International journal of pharmaceutics | 29317260 | Int J Pharm | 2018 Jun 15 |
Regenerative Engineering of the Rotator Cuff of the Shoulder. | Narayanan G, Nair LS, Laurencin CT | ACS biomaterials science & engineering | 33418763 | ACS Biomater Sci Eng | 2018 Mar 12 |
Kinetic degradation and biocompatibility evaluation of polycaprolactone-based biologics delivery matrices for regenerative engineering of the rotator cuff. | Prabhath A, Vernekar VN, Vasu V, Badon M, Avochinou JE, Asandei AD, Kumbar SG, Weber E, Laurencin CT | Journal of biomedical materials research. Part A | 33974735 | J Biomed Mater Res A | 2021 Nov |
Preparation and characterization of amnion hydrogel and its synergistic effect with adipose derived stem cells towards IL1β activated chondrocytes. | Bhattacharjee M, Ivirico JLE, Kan HM, Bordett R, Pandey R, Otsuka T, Nair LS, Laurencin CT | Scientific reports | 33127964 | Sci Rep | 2020 Oct 30 |
A Regenerative Polymer Blend Composed of Glycylglycine ethyl ester-substituted Polyphosphazene and Poly (lactic-co-glycolic acid). | Ogueri KS, Ogueri KS, Allcock HR, Laurencin CT | ACS applied polymer materials | 32699836 | ACS Appl Polym Mater | 2020 Mar 13 |
A Pandemic on a Pandemic: Racism and COVID-19 in Blacks. | Laurencin CT, Walker JM | Cell systems | 32702320 | Cell Syst | 2020 Jul 22 |
POLYMERIC BIOMATERIALS FOR SCAFFOLD-BASED BONE REGENERATIVE ENGINEERING. | Ogueri KS, Jafari T, Escobar Ivirico JL, Laurencin CT | Regenerative engineering and translational medicine | 31423461 | Regen Eng Transl Med | 2019 Jun |
Phosphate graphene as an intrinsically osteoinductive scaffold for stem cell-driven bone regeneration. | Arnold AM, Holt BD, Daneshmandi L, Laurencin CT, Sydlik SA | Proceedings of the National Academy of Sciences of the United States of America | 30796184 | Proc Natl Acad Sci U S A | 2019 Mar 12 |
The Role of Nanomaterials and Biological Agents on Rotator Cuff Regeneration. | Washington KS, Shemshaki NS, Laurencin CT | Regenerative engineering and translational medicine | 35005215 | Regen Eng Transl Med | 2021 Dec |
Ligament Regenerative Engineering: Braiding Scalable and Tunable Bioengineered Ligaments Using a Bench-Top Braiding Machine. | Mengsteab PY, Freeman J, Barajaa MA, Nair LS, Laurencin CT | Regenerative engineering and translational medicine | 35005216 | Regen Eng Transl Med | 2021 Dec |
Fabrication and characterization of mechanically competent 3D printed polycaprolactone-reduced graphene oxide scaffolds. | Seyedsalehi A, Daneshmandi L, Barajaa M, Riordan J, Laurencin CT | Scientific reports | 33335152 | Sci Rep | 2020 Dec 17 |
Graphene-Based Biomaterials for Bone Regenerative Engineering: A Comprehensive Review of the Field and Considerations Regarding Biocompatibility and Biodegradation. | Daneshmandi L, Barajaa M, Tahmasbi Rad A, Sydlik SA, Laurencin CT | Advanced healthcare materials | 33103370 | Adv Healthc Mater | 2021 Jan |
Overexpression of NDST1 Attenuates Fibrotic Response in Murine Adipose-Derived Stem Cells. | Otsuka T, Kan HM, Mason TD, Nair LS, Laurencin CT | Stem cells and development | 35920108 | Stem Cells Dev | 2022 Dec |
Regenerative Engineering Animal Models for Knee Osteoarthritis. | Esdaille CJ, Ude CC, Laurencin CT | Regenerative engineering and translational medicine | 35958163 | Regen Eng Transl Med | 2022 Jun |
Regenerative Engineering for Knee Osteoarthritis Treatment: Biomaterials and Cell-Based Technologies. | Escobar Ivirico JL, Bhattacharjee M, Kuyinu E, Nair LS, Laurencin CT | Engineering (Beijing, China) | 35392109 | Engineering (Beijing) | 2017 Feb |
Regenerative Engineering and Bionic Limbs. | James R, Laurencin CT | Rare metals | 25983525 | Rare Metals | 2015 Mar 1 |
In Vivo Evaluation of the Regenerative Capability of Glycylglycine Ethyl Ester-Substituted Polyphosphazene and Poly(lactic-co-glycolic acid) Blends: A Rabbit Critical-Sized Bone Defect Model. | Ogueri KS, Ogueri KS, McClinton A, Kan HM, Ude CC, Barajaa MA, Allcock HR, Laurencin CT | ACS biomaterials science & engineering | 33792283 | ACS Biomater Sci Eng | 2021 Apr 12 |
Nanofiber/Microsphere Hybrid Matrices In Vivo for Bone Regenerative Engineering: A Preliminary Report. | Nelson C, Khan Y, Laurencin CT | Regenerative engineering and translational medicine | 30687776 | Regen Eng Transl Med | 2018 Sep |
Microsphere-Based Scaffolds in Regenerative Engineering. | Gupta V, Khan Y, Berkland CJ, Laurencin CT, Detamore MS | Annual review of biomedical engineering | 28633566 | Annu Rev Biomed Eng | 2017 Jun 21 |
Ultra-low binder content 3D printed calcium phosphate graphene scaffolds as resorbable, osteoinductive matrices that support bone formation in vivo. | Daneshmandi L, Holt BD, Arnold AM, Laurencin CT, Sydlik SA | Scientific reports | 35484292 | Sci Rep | 2022 Apr 28 |
Enhancing the Surface Properties of a Bioengineered Anterior Cruciate Ligament Matrix for Use with Point-of-Care Stem Cell Therapy. | Yu X, Mengsteab PY, Narayanan G, Nair LS, Laurencin CT | Engineering (Beijing, China) | 34136308 | Engineering (Beijing) | 2021 Feb |
Racial Profiling Is a Public Health and Health Disparities Issue. | Laurencin CT, Walker JM | Journal of racial and ethnic health disparities | 32253746 | J Racial Ethn Health Disparities | 2020 Jun |
Evaluation of a bioengineered ACL matrix's osteointegration with BMP-2 supplementation. | Mengsteab PY, Conroy P, Badon M, Otsuka T, Kan HM, Vella AT, Nair LS, Laurencin CT | PloS one | 31910231 | PLoS One | 2020 |
Robust phenotypic maintenance of limb cells during heterogeneous culture in a physiologically relevant polymeric-based constructed graft system. | Barajaa MA, Nair LS, Laurencin CT | Scientific reports | 32678185 | Sci Rep | 2020 Jul 16 |
Nanofiber Technology for Regenerative Engineering. | Ogueri KS, Laurencin CT | ACS nano | 32678581 | ACS Nano | 2020 Aug 25 |
The synthetic artificial stem cell (SASC): Shifting the paradigm of cell therapy in regenerative engineering. | Shah S, Esdaille CJ, Bhattacharjee M, Kan HM, Laurencin CT | Proceedings of the National Academy of Sciences of the United States of America | 34987101 | Proc Natl Acad Sci U S A | 2022 Jan 11 |
Tissue Immunometabolism: Development, Physiology, and Pathobiology. | Man K, Kutyavin VI, Chawla A | Cell metabolism | 27693378 | Cell Metab | 2017 Jan 10 |
Type 2 innate lymphoid cells control eosinophil homeostasis. | Nussbaum JC, Van Dyken SJ, von Moltke J, Cheng LE, Mohapatra A, Molofsky AB, Thornton EE, Krummel MF, Chawla A, Liang HE, Locksley RM | Nature | 24037376 | Nature | 2013 Oct 10 |
Type 2 responses at the interface between immunity and fat metabolism. | Odegaard JI, Chawla A | Current opinion in immunology | 26204571 | Curr Opin Immunol | 2015 Oct |
Immunity around the clock. | Man K, Loudon A, Chawla A | Science (New York, N.Y.) | 27885005 | Science | 2016 Nov 25 |
Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin. | Mauer J, Chaurasia B, Goldau J, Vogt MC, Ruud J, Nguyen KD, Theurich S, Hausen AC, Schmitz J, Brönneke HS, Estevez E, Allen TL, Mesaros A, Partridge L, Febbraio MA, Chawla A, Wunderlich FT, Brüning JC | Nature immunology | 24681566 | Nat Immunol | 2014 May |
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Omicron spike function and neutralizing activity elicited by a comprehensive panel of vaccines. | Bowen JE, Addetia A, Dang HV, Stewart C, Brown JT, Sharkey WK, Sprouse KR, Walls AC, Mazzitelli IG, Logue JK, Franko NM, Czudnochowski N, Powell AE, Dellota E Jr, Ahmed K, Ansari AS, Cameroni E, Gori A, Bandera A, Posavad CM, Dan JM, Zhang Z, Weiskopf D, Sette A, Crotty S, Iqbal NT, Corti D, Geffner J, Snell G, Grifantini R, Chu HY, Veesler D | Science (New York, N.Y.) | 35857529 | Science | 2022 Aug 19 |
Deep mutational scans for ACE2 binding, RBD expression, and antibody escape in the SARS-CoV-2 Omicron BA.1 and BA.2 receptor-binding domains. | Starr TN, Greaney AJ, Stewart CM, Walls AC, Hannon WW, Veesler D, Bloom JD | PLoS pathogens | 36399443 | PLoS Pathog | 2022 Nov |
Functional Analysis of the Fusion and Attachment Glycoproteins of Mojiang Henipavirus. | Cheliout Da Silva S, Yan L, Dang HV, Xu K, Epstein JH, Veesler D, Broder CC | Viruses | 33809833 | Viruses | 2021 Mar 22 |
A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy. | Greaney AJ, Starr TN, Eguia RT, Loes AN, Khan K, Karim F, Cele S, Bowen JE, Logue JK, Corti D, Veesler D, Chu HY, Sigal A, Bloom JD | PLoS pathogens | 35134084 | PLoS Pathog | 2022 Feb |
Thermodynamically coupled biosensors for detecting neutralizing antibodies against SARS-CoV-2 variants. | Zhang JZ, Yeh HW, Walls AC, Wicky BIM, Sprouse KR, VanBlargan LA, Treger R, Quijano-Rubio A, Pham MN, Kraft JC, Haydon IC, Yang W, DeWitt M, Bowen JE, Chow CM, Carter L, Ravichandran R, Wener MH, Stewart L, Veesler D, Diamond MS, Greninger AL, Koelle DM, Baker D | Nature biotechnology | 35484405 | Nat Biotechnol | 2022 Sep |
Architecture and antigenicity of the Nipah virus attachment glycoprotein. | Wang Z, Amaya M, Addetia A, Dang HV, Reggiano G, Yan L, Hickey AC, DiMaio F, Broder CC, Veesler D | Science (New York, N.Y.) | 35239409 | Science | 2022 Mar 25 |
SARS-CoV-2 Omicron spike mediated immune escape and tropism shift. | Gupta R | Research square | 35075452 | Res Sq | 2022 Jan 17 |
Imprinted antibody responses against SARS-CoV-2 Omicron sublineages. | Park YJ, Pinto D, Walls AC, Liu Z, De Marco A, Benigni F, Zatta F, Silacci-Fregni C, Bassi J, Sprouse KR, Addetia A, Bowen JE, Stewart C, Giurdanella M, Saliba C, Guarino B, Schmid MA, Franko NM, Logue JK, Dang HV, Hauser K, di Iulio J, Rivera W, Schnell G, Rajesh A, Zhou J, Farhat N, Kaiser H, Montiel-Ruiz M, Noack J, Lempp FA, Janer J, Abdelnabi R, Maes P, Ferrari P, Ceschi A, Giannini O, de Melo GD, Kergoat L, Bourhy H, Neyts J, Soriaga L, Purcell LA, Snell G, Whelan SPJ, Lanzavecchia A, Virgin HW, Piccoli L, Chu HY, Pizzuto MS, Corti D, Veesler D | Science (New York, N.Y.) | 36264829 | Science | 2022 Nov 11 |
Generation of ordered protein assemblies using rigid three-body fusion. | Vulovic I, Yao Q, Park YJ, Courbet A, Norris A, Busch F, Sahasrabuddhe A, Merten H, Sahtoe DD, Ueda G, Fallas JA, Weaver SJ, Hsia Y, Langan RA, Plückthun A, Wysocki VH, Veesler D, Jensen GJ, Baker D | Proceedings of the National Academy of Sciences of the United States of America | 34074752 | Proc Natl Acad Sci U S A | 2021 Jun 8 |
Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus. | Lee J, Zepeda SK, Park YJ, Taylor AL, Quispe J, Stewart C, Leaf EM, Treichel C, Corti D, King NP, Starr TN, Veesler D | bioRxiv : the preprint server for biology | 37745523 | bioRxiv | 2023 Sep 13 |
Regulatory T cell-like response to SARS-CoV-2 in Jamaican fruit bats (Artibeus jamaicensis) transduced with human ACE2. | Burke B, Rocha SM, Zhan S, Eckley M, Reasoner C, Addetia A, Lewis J, Fagre A, Charley PA, Richt JA, Weiss SR, Tjalkens RB, Veesler D, Aboellail T, Schountz T | PLoS pathogens | 37856551 | PLoS Pathog | 2023 Oct |
Hierarchical design of pseudosymmetric protein nanoparticles. | Dowling QM, Park YJ, Gerstenmaier N, Yang EC, Wargacki A, Hsia Y, Fries CN, Ravichandran R, Walkey C, Burrell A, Veesler D, Baker D, King NP | bioRxiv : the preprint server for biology | 37398374 | bioRxiv | 2023 Jun 17 |
Molecular basis of convergent evolution of ACE2 receptor utilization among HKU5 coronaviruses. | Park YJ, Liu C, Lee J, Brown JT, Ma CB, Liu P, Xiong Q, Stewart C, Addetia A, Craig CJ, Tortorici MA, Alshukari A, Starr T, Yan H, Veesler D | bioRxiv : the preprint server for biology | 39253417 | bioRxiv | 2024 Aug 28 |
Human coronavirus HKU1 recognition of the TMPRSS2 host receptor. | McCallum M, Park YJ, Stewart C, Sprouse KR, Brown J, Tortorici MA, Gibson C, Wong E, Ieven M, Telenti A, Veesler D | bioRxiv : the preprint server for biology | 38260518 | bioRxiv | 2024 Jan 9 |
Mapping immunodominant sites on the MERS-CoV spike glycoprotein targeted by infection-elicited antibodies in humans. | Addetia A, Stewart C, Seo AJ, Sprouse KR, Asiri AY, Al-Mozaini M, Memish ZA, Alshukairi A, Veesler D | bioRxiv : the preprint server for biology | 38617298 | bioRxiv | 2024 Apr 2 |
Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines. | Walls AC, Miranda MC, Pham MN, Schäfer A, Greaney A, Arunachalam PS, Navarro MJ, Tortorici MA, Rogers K, O'Connor MA, Shireff L, Ferrell DE, Brunette N, Kepl E, Bowen J, Zepeda SK, Starr T, Hsieh CL, Fiala B, Wrenn S, Pettie D, Sydeman C, Johnson M, Blackstone A, Ravichandran R, Ogohara C, Carter L, Tilles SW, Rappuoli R, O'Hagan DT, Van Der Most R, Van Voorhis WC, McLellan JS, Kleanthous H, Sheahan TP, Fuller DH, Villinger F, Bloom J, Pulendran B, Baric R, King N, Veesler D | bioRxiv : the preprint server for biology | 33758839 | bioRxiv | 2021 Mar 16 |
Designed proteins assemble antibodies into modular nanocages. | Divine R, Dang HV, Ueda G, Fallas JA, Vulovic I, Sheffler W, Saini S, Zhao YT, Raj IX, Morawski PA, Jennewein MF, Homad LJ, Wan YH, Tooley MR, Seeger F, Etemadi A, Fahning ML, Lazarovits J, Roederer A, Walls AC, Stewart L, Mazloomi M, King NP, Campbell DJ, McGuire AT, Stamatatos L, Ruohola-Baker H, Mathieu J, Veesler D, Baker D | Science (New York, N.Y.) | 33795432 | Science | 2021 Apr 2 |
Adjuvanting a subunit COVID-19 vaccine to induce protective immunity. | Arunachalam PS, Walls AC, Golden N, Atyeo C, Fischinger S, Li C, Aye P, Navarro MJ, Lai L, Edara VV, Röltgen K, Rogers K, Shirreff L, Ferrell DE, Wrenn S, Pettie D, Kraft JC, Miranda MC, Kepl E, Sydeman C, Brunette N, Murphy M, Fiala B, Carter L, White AG, Trisal M, Hsieh CL, Russell-Lodrigue K, Monjure C, Dufour J, Spencer S, Doyle-Meyers L, Bohm RP, Maness NJ, Roy C, Plante JA, Plante KS, Zhu A, Gorman MJ, Shin S, Shen X, Fontenot J, Gupta S, O'Hagan DT, Van Der Most R, Rappuoli R, Coffman RL, Novack D, McLellan JS, Subramaniam S, Montefiori D, Boyd SD, Flynn JL, Alter G, Villinger F, Kleanthous H, Rappaport J, Suthar MS, King NP, Veesler D, Pulendran B | Nature | 33873199 | Nature | 2021 Jun |
Close relatives of MERS-CoV in bats use ACE2 as their functional receptors. | Xiong Q, Cao L, Ma C, Tortorici MA, Liu C, Si J, Liu P, Gu M, Walls AC, Wang C, Shi L, Tong F, Huang M, Li J, Zhao C, Shen C, Chen Y, Zhao H, Lan K, Corti D, Veesler D, Wang X, Yan H | Nature | 36477529 | Nature | 2022 Dec |
Structure-based design of stabilized recombinant influenza neuraminidase tetramers. | Ellis D, Lederhofer J, Acton OJ, Tsybovsky Y, Kephart S, Yap C, Gillespie RA, Creanga A, Olshefsky A, Stephens T, Pettie D, Murphy M, Sydeman C, Ahlrichs M, Chan S, Borst AJ, Park YJ, Lee KK, Graham BS, Veesler D, King NP, Kanekiyo M | Nature communications | 35383176 | Nat Commun | 2022 Apr 5 |
Antigen- and scaffold-specific antibody responses to protein nanoparticle immunogens. | Kraft JC, Pham MN, Shehata L, Brinkkemper M, Boyoglu-Barnum S, Sprouse KR, Walls AC, Cheng S, Murphy M, Pettie D, Ahlrichs M, Sydeman C, Johnson M, Blackstone A, Ellis D, Ravichandran R, Fiala B, Wrenn S, Miranda M, Sliepen K, Brouwer PJM, Antanasijevic A, Veesler D, Ward AB, Kanekiyo M, Pepper M, Sanders RW, King NP | Cell reports. Medicine | 36206752 | Cell Rep Med | 2022 Oct 18 |
Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein. | Tortorici MA, Walls AC, Joshi A, Park YJ, Eguia RT, Miranda MC, Kepl E, Dosey A, Stevens-Ayers T, Boeckh MJ, Telenti A, Lanzavecchia A, King NP, Corti D, Bloom JD, Veesler D | Cell | 35700730 | Cell | 2022 Jun 23 |
Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry. | Park YJ, De Marco A, Starr TN, Liu Z, Pinto D, Walls AC, Zatta F, Zepeda SK, Bowen JE, Sprouse KR, Joshi A, Giurdanella M, Guarino B, Noack J, Abdelnabi R, Foo SC, Rosen LE, Lempp FA, Benigni F, Snell G, Neyts J, Whelan SPJ, Virgin HW, Bloom JD, Corti D, Pizzuto MS, Veesler D | Science (New York, N.Y.) | 34990214 | Science | 2022 Jan 28 |
A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy. | Greaney AJ, Starr TN, Eguia RT, Loes AN, Khan K, Karim F, Cele S, Bowen JE, Logue JK, Corti D, Veesler D, Chu HY, Sigal A, Bloom JD | bioRxiv : the preprint server for biology | 34671768 | bioRxiv | 2021 Oct 13 |
Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry. | Park YJ, De Marco A, Starr TN, Liu Z, Pinto D, Walls AC, Zatta F, Zepeda SK, Bowen J, Sprouse KS, Joshi A, Giurdanella M, Guarino B, Noack J, Abdelnabi R, Foo SC, Lempp FA, Benigni F, Snell G, Neyts J, Whelan SP, Virgin HW, Bloom JD, Corti D, Pizzuto MS, Veesler D | bioRxiv : the preprint server for biology | 34671770 | bioRxiv | 2021 Oct 14 |
Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice. | Hunt AC, Case JB, Park YJ, Cao L, Wu K, Walls AC, Liu Z, Bowen JE, Yeh HW, Saini S, Helms L, Zhao YT, Hsiang TY, Starr TN, Goreshnik I, Kozodoy L, Carter L, Ravichandran R, Green LB, Matochko WL, Thomson CA, Vögeli B, Krüger A, VanBlargan LA, Chen RE, Ying B, Bailey AL, Kafai NM, Boyken SE, Ljubetič A, Edman N, Ueda G, Chow CM, Johnson M, Addetia A, Navarro MJ, Panpradist N, Gale M Jr, Freedman BS, Bloom JD, Ruohola-Baker H, Whelan SPJ, Stewart L, Diamond MS, Veesler D, Jewett MC, Baker D | Science translational medicine | 35412328 | Sci Transl Med | 2022 May 25 |
Spread of a SARS-CoV-2 variant through Europe in the summer of 2020. | Hodcroft EB, Zuber M, Nadeau S, Vaughan TG, Crawford KHD, Althaus CL, Reichmuth ML, Bowen JE, Walls AC, Corti D, Bloom JD, Veesler D, Mateo D, Hernando A, Comas I, González-Candelas F, SeqCOVID-SPAIN consortium, Stadler T, Neher RA | Nature | 34098568 | Nature | 2021 Jul |
Full-spike deep mutational scanning helps predict the evolutionary success of SARS-CoV-2 clades. | Dadonaite B, Brown J, McMahon TE, Farrell AG, Asarnow D, Stewart C, Logue J, Murrell B, Chu HY, Veesler D, Bloom JD | bioRxiv : the preprint server for biology | 38014024 | bioRxiv | 2023 Nov 14 |
Broadly neutralizing antibodies against emerging delta-coronaviruses. | Rexhepaj M, Park YJ, Perruzza L, Asarnow D, Mccallum M, Culap K, Saliba C, Leoni G, Balmelli A, Yoshiyama CN, Dickinson MS, Quispe J, Brown JT, Tortorici MA, Sprouse KR, Taylor AL, Starr TN, Corti D, Benigni F, Veesler D | bioRxiv : the preprint server for biology | 38617231 | bioRxiv | 2024 Apr 1 |
A pan-variant miniprotein inhibitor protects against SARS-CoV-2 variants. | Lee J, Case JB, Park YJ, Ravichandran R, Asarnow D, Tortorici MA, Brown JT, Sanapala S, Carter L, Baker D, Diamond MS, Veesler D | bioRxiv : the preprint server for biology | 39149384 | bioRxiv | 2024 Aug 10 |
Computationally designed mRNA-launched protein nanoparticle vaccines. | Hendricks GG, Grigoryan L, Navarro MJ, Catanzaro NJ, Hubbard ML, Powers JM, Mattocks M, Treichel C, Walls AC, Lee J, Ellis D, Wang JYJ, Cheng S, Miranda MC, Valdez A, Chao CW, Chan S, Men C, Johnson MR, Hui H, Wu SY, Lujan V, Muramatsu H, Lin PJC, Sung MMH, Tam YK, Leaf EM, Pardi N, Baric RS, Pulendran B, Veesler D, Schäfer A, King NP | bioRxiv : the preprint server for biology | 39091730 | bioRxiv | 2024 Jul 23 |
Computational design of prefusion-stabilized Herpesvirus gB trimers. | McCallum M, Veesler D | bioRxiv : the preprint server for biology | 39484573 | bioRxiv | 2024 Oct 24 |
Designed miniproteins potently inhibit and protect against MERS-CoV. | Ragotte RJ, Tortorici MA, Catanzaro NJ, Addetia A, Coventry B, Froggatt HM, Lee J, Stewart C, Brown JT, Goreshnik I, Sims JN, Milles LF, Wicky BIM, Glögl M, Gerben S, Kang A, Bera AK, Sharkey W, Schäfer A, Baric RS, Baker D, Veesler D | bioRxiv : the preprint server for biology | 39574666 | bioRxiv | 2024 Nov 4 |
SARS-CoV-2 nsp1 mediates broad inhibition of translation in mammals. | Gen R, Addetia A, Asarnow D, Park YJ, Quispe J, Chan MC, Brown JT, Lee J, Campbell MG, Lapointe CP, Veesler D | bioRxiv : the preprint server for biology | 39868184 | bioRxiv | 2025 Jan 15 |
Broadly neutralizing antibody cocktails targeting Nipah virus and Hendra virus fusion glycoproteins. | Dang HV, Cross RW, Borisevich V, Bornholdt ZA, West BR, Chan YP, Mire CE, Da Silva SC, Dimitrov AS, Yan L, Amaya M, Navaratnarajah CK, Zeitlin L, Geisbert TW, Broder CC, Veesler D | Nature structural & molecular biology | 33927387 | Nat Struct Mol Biol | 2021 May |
Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. | McCallum M, Walls AC, Sprouse KR, Bowen JE, Rosen LE, Dang HV, De Marco A, Franko N, Tilles SW, Logue J, Miranda MC, Ahlrichs M, Carter L, Snell G, Pizzuto MS, Chu HY, Van Voorhis WC, Corti D, Veesler D | Science (New York, N.Y.) | 34751595 | Science | 2021 Dec 24 |
Broad sarbecovirus neutralization by a human monoclonal antibody. | Tortorici MA, Czudnochowski N, Starr TN, Marzi R, Walls AC, Zatta F, Bowen JE, Jaconi S, Di Iulio J, Wang Z, De Marco A, Zepeda SK, Pinto D, Liu Z, Beltramello M, Bartha I, Housley MP, Lempp FA, Rosen LE, Dellota E Jr, Kaiser H, Montiel-Ruiz M, Zhou J, Addetia A, Guarino B, Culap K, Sprugasci N, Saliba C, Vetti E, Giacchetto-Sasselli I, Fregni CS, Abdelnabi R, Foo SC, Havenar-Daughton C, Schmid MA, Benigni F, Cameroni E, Neyts J, Telenti A, Virgin HW, Whelan SPJ, Snell G, Bloom JD, Corti D, Veesler D, Pizzuto MS | Nature | 34280951 | Nature | 2021 Sep |
Quadrivalent influenza nanoparticle vaccines induce broad protection. | Boyoglu-Barnum S, Ellis D, Gillespie RA, Hutchinson GB, Park YJ, Moin SM, Acton OJ, Ravichandran R, Murphy M, Pettie D, Matheson N, Carter L, Creanga A, Watson MJ, Kephart S, Ataca S, Vaile JR, Ueda G, Crank MC, Stewart L, Lee KK, Guttman M, Baker D, Mascola JR, Veesler D, Graham BS, King NP, Kanekiyo M | Nature | 33762730 | Nature | 2021 Apr |
Antibodies to the SARS-CoV-2 receptor-binding domain that maximize breadth and resistance to viral escape. | Starr TN, Czudnochowski N, Zatta F, Park YJ, Liu Z, Addetia A, Pinto D, Beltramello M, Hernandez P, Greaney AJ, Marzi R, Glass WG, Zhang I, Dingens AS, Bowen JE, Wojcechowskyj JA, De Marco A, Rosen LE, Zhou J, Montiel-Ruiz M, Kaiser H, Tucker H, Housley MP, di Iulio J, Lombardo G, Agostini M, Sprugasci N, Culap K, Jaconi S, Meury M, Dellota E, Cameroni E, Croll TI, Nix JC, Havenar-Daughton C, Telenti A, Lempp FA, Pizzuto MS, Chodera JD, Hebner CM, Whelan SPJ, Virgin HW, Veesler D, Corti D, Bloom JD, Snell G | bioRxiv : the preprint server for biology | 33851154 | bioRxiv | 2021 Apr 8 |
Structural basis for broad sarbecovirus neutralization by a human monoclonal antibody. | Tortorici MA, Czudnochowski N, Starr TN, Marzi R, Walls AC, Zatta F, Bowen JE, Jaconi S, di Iulio J, Wang Z, De Marco A, Zepeda SK, Pinto D, Liu Z, Beltramello M, Bartha I, Housley MP, Lempp FA, Rosen LE, Dellota E Jr, Kaiser H, Montiel-Ruiz M, Zhou J, Addetia A, Guarino B, Culap K, Sprugasci N, Saliba C, Vetti E, Giacchetto-Sasselli I, Silacci Fregni C, Abdelnabi R, Caroline Foo SY, Havenar-Daughton C, Schmid MA, Benigni F, Cameroni E, Neyts J, Telenti A, Snell G, Virgin HW, Whelan SPJ, Bloom JD, Corti D, Veesler D, Pizzuto MS | bioRxiv : the preprint server for biology | 33851169 | bioRxiv | 2021 Apr 8 |
Structural basis for broad coronavirus neutralization. | Sauer MM, Tortorici MA, Park YJ, Walls AC, Homad L, Acton O, Bowen J, Wang C, Xiong X, de van der Schueren W, Quispe J, Hoffstrom BG, Bosch BJ, McGuire AT, Veesler D | bioRxiv : the preprint server for biology | 33398277 | bioRxiv | 2021 Jan 4 |
SARS-CoV-2 breakthrough infections elicit potent, broad, and durable neutralizing antibody responses. | Walls AC, Sprouse KR, Bowen JE, Joshi A, Franko N, Navarro MJ, Stewart C, Cameroni E, McCallum M, Goecker EA, Degli-Angeli EJ, Logue J, Greninger A, Corti D, Chu HY, Veesler D | Cell | 35123650 | Cell | 2022 Mar 3 |
Multivalent designed proteins protect against SARS-CoV-2 variants of concern. | Hunt AC, Case JB, Park YJ, Cao L, Wu K, Walls AC, Liu Z, Bowen JE, Yeh HW, Saini S, Helms L, Zhao YT, Hsiang TY, Starr TN, Goreshnik I, Kozodoy L, Carter L, Ravichandran R, Green LB, Matochko WL, Thomson CA, Vögeli B, Krüger-Gericke A, VanBlargan LA, Chen RE, Ying B, Bailey AL, Kafai NM, Boyken S, Ljubetič A, Edman N, Ueda G, Chow C, Addetia A, Panpradist N, Gale M Jr, Freedman BS, Lutz BR, Bloom JD, Ruohola-Baker H, Whelan SPJ, Stewart L, Diamond MS, Veesler D, Jewett MC, Baker D | bioRxiv : the preprint server for biology | 34268509 | bioRxiv | 2021 Jul 7 |
Potent monoclonal antibody-mediated neutralization of a divergent Hendra virus variant. | Wang Z, Dang HV, Amaya M, Xu Y, Yin R, Yan L, Hickey AC, Annand EJ, Horsburgh BA, Reid PA, Smith I, Eden JS, Xu K, Broder CC, Veesler D | Proceedings of the National Academy of Sciences of the United States of America | 35617431 | Proc Natl Acad Sci U S A | 2022 May 31 |
Imprinted antibody responses against SARS-CoV-2 Omicron sublineages. | Park YJ, Pinto D, Walls AC, Liu Z, Marco A, Benigni F, Zatta F, Silacci-Fregni C, Bassi J, Sprouse KR, Addetia A, Bowen JE, Stewart C, Giurdanella M, Saliba C, Guarino B, Schmid MA, Franko N, Logue J, Dang HV, Hauser K, Iulio JD, Rivera W, Schnell G, Rajesh A, Zhou J, Farhat N, Kaiser H, Montiel-Ruiz M, Noack J, Lempp FA, Janer J, Abdelnabi R, Maes P, Ferrari P, Ceschi A, Giannini O, de Melo GD, Kergoat L, Bourhy H, Neyts J, Soriaga L, Purcell LA, Snell G, Whelan SPJ, Lanzavecchia A, Virgin HW, Piccoli L, Chu H, Pizzuto MS, Corti D, Veesler D | bioRxiv : the preprint server for biology | 35677069 | bioRxiv | 2022 Aug 22 |
Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution. | Starr TN, Greaney AJ, Hannon WW, Loes AN, Hauser K, Dillen JR, Ferri E, Farrell AG, Dadonaite B, McCallum M, Matreyek KA, Corti D, Veesler D, Snell G, Bloom JD | Science (New York, N.Y.) | 35762884 | Science | 2022 Jul 22 |
Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies. | Collier DA, De Marco A, Ferreira IATM, Meng B, Datir RP, Walls AC, Kemp SA, Bassi J, Pinto D, Silacci-Fregni C, Bianchi S, Tortorici MA, Bowen J, Culap K, Jaconi S, Cameroni E, Snell G, Pizzuto MS, Pellanda AF, Garzoni C, Riva A, CITIID-NIHR BioResource COVID-19 Collaboration, Elmer A, Kingston N, Graves B, McCoy LE, Smith KGC, Bradley JR, Temperton N, Ceron-Gutierrez L, Barcenas-Morales G, COVID-19 Genomics UK (COG-UK) Consortium, Harvey W, Virgin HW, Lanzavecchia A, Piccoli L, Doffinger R, Wills M, Veesler D, Corti D, Gupta RK | Nature | 33706364 | Nature | 2021 May |
Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2. | Walls AC, Fiala B, Schäfer A, Wrenn S, Pham MN, Murphy M, Tse LV, Shehata L, O'Connor MA, Chen C, Navarro MJ, Miranda MC, Pettie D, Ravichandran R, Kraft JC, Ogohara C, Palser A, Chalk S, Lee EC, Guerriero K, Kepl E, Chow CM, Sydeman C, Hodge EA, Brown B, Fuller JT, Dinnon KH 3rd, Gralinski LE, Leist SR, Gully KL, Lewis TB, Guttman M, Chu HY, Lee KK, Fuller DH, Baric RS, Kellam P, Carter L, Pepper M, Sheahan TP, Veesler D, King NP | Cell | 33160446 | Cell | 2020 Nov 25 |
SARS-CoV-2 spike conformation determines plasma neutralizing activity. | Bowen JE, Walls AC, Joshi A, Sprouse KR, Stewart C, Tortorici MA, Franko NM, Logue JK, Mazzitelli IG, Tiles SW, Ahmed K, Shariq A, Snell G, Iqbal NT, Geffner J, Bandera A, Gori A, Grifantini R, Chu HY, Van Voorhis WC, Corti D, Veesler D | bioRxiv : the preprint server for biology | 34981060 | bioRxiv | 2021 Dec 21 |
ACE2 binding is an ancestral and evolvable trait of sarbecoviruses. | Starr TN, Zepeda SK, Walls AC, Greaney AJ, Alkhovsky S, Veesler D, Bloom JD | Nature | 35114688 | Nature | 2022 Mar |
Delta breakthrough infections elicit potent, broad and durable neutralizing antibody responses. | Walls AC, Sprouse KR, Joshi A, Bowen JE, Franko N, Navarro MJ, Stewart C, McCallum M, Goecker EA, Degli-Angeli EJ, Logue J, Greninger A, Chu H, Veesler D | bioRxiv : the preprint server for biology | 34931192 | bioRxiv | 2021 Dec 13 |
Distinct sensitivities to SARS-CoV-2 variants in vaccinated humans and mice. | Walls AC, VanBlargan LA, Wu K, Choi A, Navarro MJ, Lee D, Avena L, Berrueta DM, Pham MN, Elbashir S, Kraft JC, Miranda MC, Kepl E, Johnson M, Blackstone A, Sprouse K, Fiala B, O'Connor MA, Brunette N, Arunachalam PS, Shirreff L, Rogers K, Carter L, Fuller DH, Villinger F, Pulendran B, Diamond MS, Edwards DK, King NP, Veesler D | Cell reports | 35988541 | Cell Rep | 2022 Aug 30 |
Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escape. | Marzi R, Bassi J, Silacci-Fregni C, Bartha I, Muoio F, Culap K, Sprugasci N, Lombardo G, Saliba C, Cameroni E, Cassotta A, Low JS, Walls AC, McCallum M, Tortorici MA, Bowen JE, Dellota EA Jr, Dillen JR, Czudnochowski N, Pertusini L, Terrot T, Lepori V, Tarkowski M, Riva A, Biggiogero M, Pellanda AF, Garzoni C, Ferrari P, Ceschi A, Giannini O, Havenar-Daughton C, Telenti A, Arvin A, Virgin HW, Sallusto F, Veesler D, Lanzavecchia A, Corti D, Piccoli L | bioRxiv : the preprint server for biology | 36203553 | bioRxiv | 2022 Sep 30 |
SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines. | Bowen JE, Park YJ, Stewart C, Brown JT, Sharkey WK, Walls AC, Joshi A, Sprouse KR, McCallum M, Tortorici MA, Franko NM, Logue JK, Mazzitelli IG, Nguyen AW, Silva RP, Huang Y, Low JS, Jerak J, Tiles SW, Ahmed K, Shariq A, Dan JM, Zhang Z, Weiskopf D, Sette A, Snell G, Posavad CM, Iqbal NT, Geffner J, Bandera A, Gori A, Sallusto F, Maynard JA, Crotty S, Van Voorhis WC, Simmerling C, Grifantini R, Chu HY, Corti D, Veesler D | Science immunology | 36356052 | Sci Immunol | 2022 Dec 23 |
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Structural changes in the SARS-CoV-2 spike E406W mutant escaping a clinical monoclonal antibody cocktail. | Addetia A, Park YJ, Starr T, Greaney AJ, Sprouse KR, Bowen JE, Tiles SW, Van Voorhis WC, Bloom JD, Corti D, Walls AC, Veesler D | Cell reports | 37300832 | Cell Rep | 2023 Jun 27 |
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Spike deep mutational scanning helps predict success of SARS-CoV-2 clades. | Dadonaite B, Brown J, McMahon TE, Farrell AG, Figgins MD, Asarnow D, Stewart C, Lee J, Logue J, Bedford T, Murrell B, Chu HY, Veesler D, Bloom JD | Nature | 38961298 | Nature | 2024 Jul |
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Vaccine design via antigen reorientation. | Xu D, Carter JJ, Li C, Utz A, Weidenbacher PAB, Tang S, Sanyal M, Pulendran B, Barnes CO, Kim PS | Nature chemical biology | 38225471 | Nat Chem Biol | 2024 Aug |
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Converting non-neutralizing SARS-CoV-2 antibodies into broad-spectrum inhibitors. | Weidenbacher PA, Waltari E, de Los Rios Kobara I, Bell BN, Morris MK, Cheng YC, Hanson C, Pak JE, Kim PS | Nature chemical biology | 36076082 | Nat Chem Biol | 2022 Nov |
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Engineering a SARS-CoV-2 vaccine targeting the RBD cryptic-face via immunofocusing. | Bruun TUJ, Do J, Weidenbacher PA, Kim PS | bioRxiv : the preprint server for biology | 38895327 | bioRxiv | 2024 Jun 5 |
A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates. | Weidenbacher PA, Sanyal M, Friedland N, Tang S, Arunachalam PS, Hu M, Kumru OS, Morris MK, Fontenot J, Shirreff L, Do J, Cheng YC, Vasudevan G, Feinberg MB, Villinger FJ, Hanson C, Joshi SB, Volkin DB, Pulendran B, Kim PS | Nature communications | 37069151 | Nat Commun | 2023 Apr 17 |
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Multimerization of Ebola GPΔmucin on protein nanoparticle vaccines has minimal effect on elicitation of neutralizing antibodies. | Powell AE, Xu D, Roth GA, Zhang K, Chiu W, Appel EA, Kim PS | Frontiers in immunology | 36091016 | Front Immunol | 2022 |
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Enhancing HIV-1 Neutralization by Increasing the Local Concentration of Membrane-Proximal External Region-Directed Broadly Neutralizing Antibodies. | Kim S, Filsinger Interrante MV, Kim PS | Journal of virology | 36541800 | J Virol | 2023 Jan 31 |
HIV-1 prehairpin intermediate inhibitors show efficacy independent of neutralization tier. | Bell BN, Bruun TUJ, Friedland N, Kim PS | Proceedings of the National Academy of Sciences of the United States of America | 36795752 | Proc Natl Acad Sci U S A | 2023 Feb 21 |
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Decreased efficacy of a COVID-19 vaccine due to mutations present in early SARS-CoV-2 variants of concern. | Weidenbacher PA, Friedland N, Sanyal M, Morris MK, Do J, Hanson C, Kim PS | bioRxiv : the preprint server for biology | 37425802 | bioRxiv | 2023 Jun 29 |
Structure-guided stabilization improves the ability of the HIV-1 gp41 hydrophobic pocket to elicit neutralizing antibodies. | Bruun TUJ, Tang S, Erwin G, Deis L, Fernandez D, Kim PS | The Journal of biological chemistry | 36841484 | J Biol Chem | 2023 Apr |
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Antigen discovery tools for adaptive immune receptor repertoire research. | Bousbaine D, Ploegh HL | Current opinion in systems biology | 33195881 | Curr Opin Syst Biol | 2020 Dec |
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Asparaginyl Ligase-Catalyzed One-Step Cell Surface Modification of Red Blood Cells. | Harmand TJ, Pishesha N, Rehm FBH, Ma W, Pinney WB, Xie YJ, Ploegh HL | ACS chemical biology | 34129316 | ACS Chem Biol | 2021 Jul 16 |
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Nanobodies as non-invasive imaging tools. | Rashidian M, Ploegh H | Immuno-oncology technology | 35754459 | Immunooncol Technol | 2020 Sep |
An armed anti-immunoglobulin light chain nanobody protects mice against influenza A and B infections. | Liu X, Balligand T, Carpenet C, Ploegh HL | Science immunology | 37352373 | Sci Immunol | 2023 Jun 23 |
Nanobody-based CAR NK cells for possible immunotherapy of MICA(+) tumors. | Verhaar ER, van Keizerswaard WJC, Knoflook A, Balligand T, Ploegh HL | PNAS nexus | 38756234 | PNAS Nexus | 2024 May |
A monoclonal antibody that recognizes a unique 13-residue epitope in the cytoplasmic tail of HLA-E. | Verhaar ER, Gan J, Buhl S, Li Z, Horowitz A, Ploegh HL | Molecular immunology | 38901180 | Mol Immunol | 2024 Aug |
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MICA-specific nanobodies for diagnosis and immunotherapy of MICA(+) tumors. | Verhaar ER, Knoflook A, Pishesha N, Liu X, van Keizerswaard WJC, Wucherpfennig KW, Ploegh HL | Frontiers in immunology | 38550583 | Front Immunol | 2024 |
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CD4+ T cells regulate sickness-induced anorexia and fat wasting during a chronic parasitic infection. | Redford SE, Varanasi SK, Sanchez KK, Thorup NR, Ayres JS | Cell reports | 37490905 | Cell Rep | 2023 Aug 29 |
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Fluoxetine promotes IL-10-dependent metabolic defenses to protect from sepsis-induced lethality. | Gallant RM, Sanchez KK, Joulia E, Snyder JM, Metallo CM, Ayres JS | Science advances | 39951524 | Sci Adv | 2025 Feb 14 |
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Surviving COVID-19: A disease tolerance perspective. | Ayres JS | Science advances | 32494691 | Sci Adv | 2020 May |
Adipose triglyceride lipase mediates lipolysis and lipid mobilization in response to iron-mediated negative energy balance. | Romero AR, Mu A, Ayres JS | iScience | 35265813 | iScience | 2022 Mar 18 |
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Commensal Candida albicans Positively Calibrates Systemic Th17 Immunological Responses. | Shao TY, Ang WXG, Jiang TT, Huang FS, Andersen H, Kinder JM, Pham G, Burg AR, Ruff B, Gonzalez T, Khurana Hershey GK, Haslam DB, Way SS | Cell host & microbe | 30870622 | Cell Host Microbe | 2019 Mar 13 |
Vaccination strategies to enhance immunity in neonates. | Kollmann TR, Marchant A, Way SS | Science (New York, N.Y.) | 32381718 | Science | 2020 May 8 |
Mouse models of neutropenia reveal progenitor-stage-specific defects. | Muench DE, Olsson A, Ferchen K, Pham G, Serafin RA, Chutipongtanate S, Dwivedi P, Song B, Hay S, Chetal K, Trump-Durbin LR, Mookerjee-Basu J, Zhang K, Yu JC, Lutzko C, Myers KC, Nazor KL, Greis KD, Kappes DJ, Way SS, Salomonis N, Grimes HL | Nature | 32494068 | Nature | 2020 Jun |
CD8(+) T Cell Functional Exhaustion Overrides Pregnancy-Induced Fetal Antigen Alloimmunization. | Kinder JM, Turner LH, Stelzer IA, Miller-Handley H, Burg A, Shao TY, Pham G, Way SS | Cell reports | 32579916 | Cell Rep | 2020 Jun 23 |
Persistent Zika Virus Clinical Susceptibility despite Reduced Viral Burden in Mice with Expanded Virus-Specific CD8(+) T Cells Primed by Recombinant Listeria monocytogenes. | Burg AR, Erickson JJ, Turner LH, Pham G, Kinder JM, Way SS | Journal of immunology (Baltimore, Md. : 1950) | 32522837 | J Immunol | 2020 Jul 15 |
Friendly fungi: symbiosis with commensal Candida albicans. | Shao TY, Haslam DB, Bennett RJ, Way SS | Trends in immunology | 35961916 | Trends Immunol | 2022 Sep |
Intestinal epithelial HDAC3 and MHC class II coordinate microbiota-specific immunity. | Eshleman EM, Shao TY, Woo V, Rice T, Engleman L, Didriksen BJ, Whitt J, Haslam DB, Way SS, Alenghat T | The Journal of clinical investigation | 36602872 | J Clin Invest | 2023 Feb 15 |
Maternal Vaccination to Prevent Adverse Pregnancy Outcomes: An Underutilized Molecular Immunological Intervention? | Giles ML, Way SS, Marchant A, Aghaepour N, James T, Schaltz-Buchholzer F, Zazara D, Arck P, Kollmann TR | Journal of molecular biology | 37080422 | J Mol Biol | 2023 Jul 1 |
Resilient anatomy and local plasticity of naive and stress haematopoiesis. | Wu Q, Zhang J, Kumar S, Shen S, Kincaid M, Johnson CB, Zhang YS, Turcotte R, Alt C, Ito K, Homan S, Sherman BE, Shao TY, Slaughter A, Weinhaus B, Song B, Filippi MD, Grimes HL, Lin CP, Ito K, Way SS, Kofron JM, Lucas D | Nature | 38509363 | Nature | 2024 Mar |
Preconceptual Zika virus asymptomatic infection protects against secondary prenatal infection. | Turner LH, Kinder JM, Wilburn A, D'Mello RJ, Braunlin MR, Jiang TT, Pham G, Way SS | PLoS pathogens | 29145516 | PLoS Pathog | 2017 Nov |
Fungus Among Us: The Frenemies Within. | Aggor FEY, Way SS, Gaffen SL | Trends in immunology | 31053496 | Trends Immunol | 2019 Jun |
Immunological Basis for Recurrent Fetal Loss and Pregnancy Complications. | Deshmukh H, Way SS | Annual review of pathology | 30183507 | Annu Rev Pathol | 2019 Jan 24 |
Declining responsiveness to influenza vaccination with progression of human pregnancy. | Schlaudecker EP, Ambroggio L, McNeal MM, Finkelman FD, Way SS | Vaccine | 29941326 | Vaccine | 2018 Jul 25 |
Commensal Fungi Recapitulate the Protective Benefits of Intestinal Bacteria. | Jiang TT, Shao TY, Ang WXG, Kinder JM, Turner LH, Pham G, Whitt J, Alenghat T, Way SS | Cell host & microbe | 29174402 | Cell Host Microbe | 2017 Dec 13 |
Epidemiology of Pregnancy Complications Through the Lens of Immunological Memory. | Gregory EJ, Liu J, Miller-Handley H, Kinder JM, Way SS | Frontiers in immunology | 34248991 | Front Immunol | 2021 |
Tacrolimus exposure windows responsible for Listeria monocytogenes infection susceptibility. | Miller-Handley H, Erickson JJ, Gregory EJ, Prasanphanich NS, Shao TY, Way SS | Transplant infectious disease : an official journal of the Transplantation Society | 34057792 | Transpl Infect Dis | 2021 Aug |
Systematic reconstruction of an effector-gene network reveals determinants of Salmonella cellular and tissue tropism. | Chen D, Burford WB, Pham G, Zhang L, Alto LT, Ertelt JM, Winter MG, Winter SE, Way SS, Alto NM | Cell host & microbe | 34536347 | Cell Host Microbe | 2021 Oct 13 |
Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation. | Shao TY, Jiang TT, Stevens J, Russi AE, Troutman TD, Bernieh A, Pham G, Erickson JJ, Eshleman EM, Alenghat T, Jameson SC, Hogquist KA, Weaver CT, Haslam DB, Deshmukh H, Way SS | Cell reports | 37889750 | Cell Rep | 2023 Nov 28 |
Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity. | Shao TY, Kakade P, Witchley JN, Frazer C, Murray KL, Ene IV, Haslam DB, Hagan T, Noble SM, Bennett RJ, Way SS | Cell reports | 35584674 | Cell Rep | 2022 May 17 |
The induction of preterm labor in rhesus macaques is determined by the strength of immune response to intrauterine infection. | Cappelletti M, Presicce P, Feiyang M, Senthamaraikannan P, Miller LA, Pellegrini M, Sim MS, Jobe AH, Divanovic S, Way SS, Chougnet CA, Kallapur SG | PLoS biology | 34495952 | PLoS Biol | 2021 Sep |
In situ mapping identifies distinct vascular niches for myelopoiesis. | Zhang J, Wu Q, Johnson CB, Pham G, Kinder JM, Olsson A, Slaughter A, May M, Weinhaus B, D'Alessandro A, Engel JD, Jiang JX, Kofron JM, Huang LF, Prasath VBS, Way SS, Salomonis N, Grimes HL, Lucas D | Nature | 33568812 | Nature | 2021 Feb |
Immunology of Uterine and Vaginal Mucosae: (Trends in Immunology 39, 302-314, 2018). | Zhou JZ, Way SS, Chen K | Trends in immunology | 29530651 | Trends Immunol | 2018 Apr |
IL-17-producing γδ T cells protect against Clostridium difficile infection. | Chen YS, Chen IB, Pham G, Shao TY, Bangar H, Way SS, Haslam DB | The Journal of clinical investigation | 31990686 | J Clin Invest | 2020 May 1 |
Immunological implications of pregnancy-induced microchimerism. | Kinder JM, Stelzer IA, Arck PC, Way SS | Nature reviews. Immunology | 28480895 | Nat Rev Immunol | 2017 Aug |
Maternal-fetal conflict averted by progesterone- induced FOXP3+ regulatory T cells. | Severance AL, Kinder JM, Xin L, Burg AR, Shao TY, Pham G, Tilburgs T, Goodman WA, Mesiano S, Way SS | iScience | 35637736 | iScience | 2022 Jun 17 |
Reproductive outcomes after pregnancy-induced displacement of preexisting microchimeric cells. | Shao TY, Kinder JM, Harper G, Pham G, Peng Y, Liu J, Gregory EJ, Sherman BE, Wu Y, Iten AE, Hu YC, Russi AE, Erickson JJ, Miller-Handley H, Way SS | Science (New York, N.Y.) | 37733857 | Science | 2023 Sep 22 |
Preconceptual Priming Overrides Susceptibility to Escherichia coli Systemic Infection during Pregnancy. | Prasanphanich NS, Gregory EJ, Erickson JJ, Miller-Handley H, Kinder JM, Way SS | mBio | 33622714 | mBio | 2021 Feb 23 |
Immunology of the Uterine and Vaginal Mucosae. | Zhou JZ, Way SS, Chen K | Trends in immunology | 29433961 | Trends Immunol | 2018 Apr |
Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages. | Yang JD, Mott D, Sutiwisesak R, Lu YJ, Raso F, Stowell B, Babunovic GH, Lee J, Carpenter SM, Way SS, Fortune SM, Behar SM | PLoS pathogens | 29782535 | PLoS Pathog | 2018 Feb |
A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice. | Deshpande NR, Uhrlaub JL, Way SS, Nikolich-Žugich J, Kuhns MS | PloS one | 29864157 | PLoS One | 2018 |
Pregnancy enables antibody protection against intracellular infection. | Erickson JJ, Archer-Hartmann S, Yarawsky AE, Miller JLC, Seveau S, Shao TY, Severance AL, Miller-Handley H, Wu Y, Pham G, Wasik BR, Parrish CR, Hu YC, Lau JTY, Azadi P, Herr AB, Way SS | Nature | 35676476 | Nature | 2022 Jun |
The effect of antibiotics on protein diffusion in the Escherichia coli cytoplasmic membrane. | Liu GS, Bratton BP, Gitai Z, Shaevitz JW | PloS one | 28977034 | PLoS One | 2017 |
Pseudomonas aeruginosa distinguishes surfaces by stiffness using retraction of type IV pili. | Koch MD, Black ME, Han E, Shaevitz JW, Gitai Z | Proceedings of the National Academy of Sciences of the United States of America | 35561220 | Proc Natl Acad Sci U S A | 2022 May 17 |
The curved shape of Caulobacter crescentus enhances surface colonization in flow. | Persat A, Stone HA, Gitai Z | Nature communications | 24806788 | Nat Commun | 2014 May 8 |
Pseudomonas aeruginosa detachment from surfaces via a self-made small molecule. | Scheffler RJ, Sugimoto Y, Bratton BP, Ellison CK, Koch MD, Donia MS, Gitai Z | The Journal of biological chemistry | 33450229 | J Biol Chem | 2021 Jan-Jun |
Algal p-coumaric acid induces oxidative stress and siderophore biosynthesis in the bacterial symbiont Phaeobacter inhibens. | Wang R, Gallant É, Wilson MZ, Wu Y, Li A, Gitai Z, Seyedsayamdost MR | Cell chemical biology | 34437838 | Cell Chem Biol | 2022 Apr 21 |
Subcellular localization of type IV pili regulates bacterial multicellular development. | Ellison CK, Fei C, Dalia TN, Wingreen NS, Dalia AB, Shaevitz JW, Gitai Z | Nature communications | 36284096 | Nat Commun | 2022 Oct 25 |
Global and gene-specific translational regulation in Escherichia coli across different conditions. | Zhang D, Li SH, King CG, Wingreen NS, Gitai Z, Li Z | PLoS computational biology | 36264977 | PLoS Comput Biol | 2022 Oct |
Single-cell massively-parallel multiplexed microbial sequencing (M3-seq) identifies rare bacterial populations and profiles phage infection. | Wang B, Lin AE, Yuan J, Novak KE, Koch MD, Wingreen NS, Adamson B, Gitai Z | Nature microbiology | 37653008 | Nat Microbiol | 2023 Oct |
Type IV pili mechanochemically regulate virulence factors in Pseudomonas aeruginosa. | Persat A, Inclan YF, Engel JN, Stone HA, Gitai Z | Proceedings of the National Academy of Sciences of the United States of America | 26041805 | Proc Natl Acad Sci U S A | 2015 Jun 16 |
Escherichia coli translation strategies differ across carbon, nitrogen and phosphorus limitation conditions. | Li SH, Li Z, Park JO, King CG, Rabinowitz JD, Wingreen NS, Gitai Z | Nature microbiology | 30038306 | Nat Microbiol | 2018 Aug |
Mode of action and resistance studies unveil new roles for tropodithietic acid as an anticancer agent and the γ-glutamyl cycle as a proton sink. | Wilson MZ, Wang R, Gitai Z, Seyedsayamdost MR | Proceedings of the National Academy of Sciences of the United States of America | 26802120 | Proc Natl Acad Sci U S A | 2016 Feb 9 |
Human CTP synthase filament structure reveals the active enzyme conformation. | Lynch EM, Hicks DR, Shepherd M, Endrizzi JA, Maker A, Hansen JM, Barry RM, Gitai Z, Baldwin EP, Kollman JM | Nature structural & molecular biology | 28459447 | Nat Struct Mol Biol | 2017 Jun |
Acinetobacter baylyi regulates type IV pilus synthesis by employing two extension motors and a motor protein inhibitor. | Ellison CK, Dalia TN, Klancher CA, Shaevitz JW, Gitai Z, Dalia AB | Nature communications | 34145281 | Nat Commun | 2021 Jun 18 |
A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance. | Martin JK 2nd, Sheehan JP, Bratton BP, Moore GM, Mateus A, Li SH, Kim H, Rabinowitz JD, Typas A, Savitski MM, Wilson MZ, Gitai Z | Cell | 32497502 | Cell | 2020 Jun 25 |
Bacterial viability in the built environment of the home. | Xie J, Acosta EM, Gitai Z | PloS one | 37939059 | PLoS One | 2023 |
Microfluidic-based transcriptomics reveal force-independent bacterial rheosensing. | Sanfilippo JE, Lorestani A, Koch MD, Bratton BP, Siryaporn A, Stone HA, Gitai Z | Nature microbiology | 31086313 | Nat Microbiol | 2019 Aug |
Light-based control of metabolic flux through assembly of synthetic organelles. | Zhao EM, Suek N, Wilson MZ, Dine E, Pannucci NL, Gitai Z, Avalos JL, Toettcher JE | Nature chemical biology | 31086330 | Nat Chem Biol | 2019 Jun |
Modeling microbial metabolic trade-offs in a chemostat. | Li Z, Liu B, Li SH, King CG, Gitai Z, Wingreen NS | PLoS computational biology | 32857772 | PLoS Comput Biol | 2020 Aug |
How to Build a Bacterial Cell: MreB as the Foreman of E. coli Construction. | Shi H, Bratton BP, Gitai Z, Huang KC | Cell | 29522748 | Cell | 2018 Mar 8 |
CrvA and CrvB form a curvature-inducing module sufficient to induce cell-shape complexity in Gram-negative bacteria. | Martin NR, Blackman E, Bratton BP, Chase KJ, Bartlett TM, Gitai Z | Nature microbiology | 34183815 | Nat Microbiol | 2021 Jul |
Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma. | Ducker GS, Ghergurovich JM, Mainolfi N, Suri V, Jeong SK, Hsin-Jung Li S, Friedman A, Manfredi MG, Gitai Z, Kim H, Rabinowitz JD | Proceedings of the National Academy of Sciences of the United States of America | 29073064 | Proc Natl Acad Sci U S A | 2017 Oct 24 |
Both clinical and environmental Caulobacter species are virulent in the Galleria mellonella infection model. | Moore GM, Gitai Z | PloS one | 32163465 | PLoS One | 2020 |
Pseudomonas aeruginosa clinical blood isolates display significant phenotypic variability. | Scheffler RJ, Bratton BP, Gitai Z | PloS one | 35793311 | PLoS One | 2022 |
Competitive binding of independent extension and retraction motors explains the quantitative dynamics of type IV pili. | Koch MD, Fei C, Wingreen NS, Shaevitz JW, Gitai Z | Proceedings of the National Academy of Sciences of the United States of America | 33593905 | Proc Natl Acad Sci U S A | 2021 Feb 23 |
Cytotoxic alkyl-quinolones mediate surface-induced virulence in Pseudomonas aeruginosa. | Vrla GD, Esposito M, Zhang C, Kang Y, Seyedsayamdost MR, Gitai Z | PLoS pathogens | 32925969 | PLoS Pathog | 2020 Sep |
Mechanical Genomic Studies Reveal the Role of d-Alanine Metabolism in Pseudomonas aeruginosa Cell Stiffness. | Trivedi RR, Crooks JA, Auer GK, Pendry J, Foik IP, Siryaporn A, Abbott NL, Gitai Z, Weibel DB | mBio | 30206169 | mBio | 2018 Sep 11 |
Post-transcriptional gene regulation by an Hfq-independent small RNA in Caulobacter crescentus. | Fröhlich KS, Förstner KU, Gitai Z | Nucleic acids research | 30165530 | Nucleic Acids Res | 2018 Nov 16 |
A Periplasmic Polymer Curves Vibrio cholerae and Promotes Pathogenesis. | Bartlett TM, Bratton BP, Duvshani A, Miguel A, Sheng Y, Martin NR, Nguyen JP, Persat A, Desmarais SM, VanNieuwenhze MS, Huang KC, Zhu J, Shaevitz JW, Gitai Z | Cell | 28086090 | Cell | 2017 Jan 12 |
A scaffold protein connects type IV pili with the Chp chemosensory system to mediate activation of virulence signaling in Pseudomonas aeruginosa. | Inclan YF, Persat A, Greninger A, Von Dollen J, Johnson J, Krogan N, Gitai Z, Engel JN | Molecular microbiology | 27145134 | Mol Microbiol | 2016 Aug |
Surface association sensitizes Pseudomonas aeruginosa to quorum sensing. | Chuang SK, Vrla GD, Fröhlich KS, Gitai Z | Nature communications | 31511506 | Nat Commun | 2019 Sep 11 |
The mechanical world of bacteria. | Persat A, Nadell CD, Kim MK, Ingremeau F, Siryaporn A, Drescher K, Wingreen NS, Bassler BL, Gitai Z, Stone HA | Cell | 26000479 | Cell | 2015 May 21 |
Colonization, competition, and dispersal of pathogens in fluid flow networks. | Siryaporn A, Kim MK, Shen Y, Stone HA, Gitai Z | Current biology : CB | 25843031 | Curr Biol | 2015 May 4 |
Bacterial DNA on the skin surface overrepresents the viable skin microbiome. | Acosta EM, Little KA, Bratton BP, Lopez JG, Mao X, Payne AS, Donia M, Devenport D, Gitai Z | eLife | 37389570 | Elife | 2023 Jun 30 |
Cas9(+) conditionally-immortalized macrophages as a tool for bacterial pathogenesis and beyond. | Roberts AW, Popov LM, Mitchell G, Ching KL, Licht DJ, Golovkine G, Barton GM, Cox JS | eLife | 31204998 | Elife | 2019 Jun 17 |
An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses. | Penn BH, Netter Z, Johnson JR, Von Dollen J, Jang GM, Johnson T, Ohol YM, Maher C, Bell SL, Geiger K, Golovkine G, Du X, Choi A, Parry T, Mohapatra BC, Storck MD, Band H, Chen C, Jäger S, Shales M, Portnoy DA, Hernandez R, Coscoy L, Cox JS, Krogan NJ | Molecular cell | 30118682 | Mol Cell | 2018 Aug 16 |
TRIM14 Is a Key Regulator of the Type I IFN Response during Mycobacterium tuberculosis Infection. | Hoffpauir CT, Bell SL, West KO, Jing T, Wagner AR, Torres-Odio S, Cox JS, West AP, Li P, Patrick KL, Watson RO | Journal of immunology (Baltimore, Md. : 1950) | 32404352 | J Immunol | 2020 Jul 1 |
Ribosome Rescue Inhibitors Kill Actively Growing and Nonreplicating Persister Mycobacterium tuberculosis Cells. | Alumasa JN, Manzanillo PS, Peterson ND, Lundrigan T, Baughn AD, Cox JS, Keiler KC | ACS infectious diseases | 28762275 | ACS Infect Dis | 2017 Sep 8 |
Dynamic post-translational modification profiling of Mycobacterium tuberculosis-infected primary macrophages. | Budzik JM, Swaney DL, Jimenez-Morales D, Johnson JR, Garelis NE, Repasy T, Roberts AW, Popov LM, Parry TJ, Pratt D, Ideker T, Krogan NJ, Cox JS | eLife | 31951200 | Elife | 2020 Jan 17 |
Tax1bp1 enhances bacterial virulence and promotes inflammatory responses during Mycobacterium tuberculosis infection of alveolar macrophages. | Chin J, Abeydeera N, Repasy T, Rivera-Lugo R, Mitchell G, Nguyen VQ, Zheng W, Richards A, Swaney DL, Krogan NJ, Ernst JD, Cox JS, Budzik JM | bioRxiv : the preprint server for biology | 39763950 | bioRxiv | 2024 Dec 16 |
Neuromodulation of Courtship Drive through Tyramine-Responsive Neurons in the Drosophila Brain. | Huang J, Liu W, Qi YX, Luo J, Montell C | Current biology : CB | 27498566 | Curr Biol | 2016 Sep 12 |
The Role of Y Chromosome Genes in Male Fertility in Drosophila melanogaster. | Zhang J, Luo J, Chen J, Dai J, Montell C | Genetics | 32404399 | Genetics | 2020 Jul |
Elimination of vision-guided target attraction in Aedes aegypti using CRISPR. | Zhan Y, Alonso San Alberto D, Rusch C, Riffell JA, Montell C | Current biology : CB | 34331858 | Curr Biol | 2021 Sep 27 |
A Temperature Gradient Assay to Determine Thermal Preferences of Drosophila Larvae. | Liu J, Sokabe T, Montell C | Journal of visualized experiments : JoVE | 29985331 | J Vis Exp | 2018 Jun 25 |
Suppression of female fertility in Aedes aegypti with a CRISPR-targeted male-sterile mutation. | Chen J, Luo J, Wang Y, Gurav AS, Li M, Akbari OS, Montell C | Proceedings of the National Academy of Sciences of the United States of America | 34031258 | Proc Natl Acad Sci U S A | 2021 Jun 1 |
Unconventional Roles of Opsins. | Leung NY, Montell C | Annual review of cell and developmental biology | 28598695 | Annu Rev Cell Dev Biol | 2017 Oct 6 |
Neuropeptide F regulates courtship in Drosophila through a male-specific neuronal circuit. | Liu W, Ganguly A, Huang J, Wang Y, Ni JD, Gurav AS, Aguilar MA, Montell C | eLife | 31403399 | Elife | 2019 Aug 12 |
Differential regulation of the Drosophila sleep homeostat by circadian and arousal inputs. | Ni JD, Gurav AS, Liu W, Ogunmowo TH, Hackbart H, Elsheikh A, Verdegaal AA, Montell C | eLife | 30719975 | Elife | 2019 Feb 5 |
Pseudotyping of HIV-1 with Human T-Lymphotropic Virus 1 (HTLV-1) Envelope Glycoprotein during HIV-1-HTLV-1 Coinfection Facilitates Direct HIV-1 Infection of Female Genital Epithelial Cells: Implications for Sexual Transmission of HIV-1. | Tang Y, George AM, Petrechko O, Nouvet FJ, Sweet SD, Tanaka Y, Imbiakha BS, Jiang G, Gao W, Anastos K, Hildreth JEK | mSphere | 29624497 | mSphere | 2018 Apr 25 |
Optimizing Temporal Waveform Analysis: A Novel Pipeline for Efficient Characterization of Left Coronary Artery Velocity Profiles. | Geddes JR, Randles A | ArXiv | 38410654 | ArXiv | 2024 Feb 15 |
Investigating the Influence of Heterogeneity Within Cell Types on Microvessel Network Transport. | Nan J, Roychowdhury S, Randles A | Cellular and molecular bioengineering | 38099216 | Cell Mol Bioeng | 2023 Dec |
Modeling the effect of patient size on cerebral perfusion during veno-arterial extracorporeal membrane oxygenation. | Feiger B, Jensen CW, Bryner BS, Segars WP, Randles A | Perfusion | 37395266 | Perfusion | 2024 Oct |
Cloud Computing to Enable Wearable-Driven Longitudinal Hemodynamic Maps. | Tanade C, Rakestraw E, Ladd W, Draeger E, Randles A | International Conference for High Performance Computing, Networking, Storage and Analysis : [proceedings]. SC (Conference : Supercomputing) | 38939612 | Int Conf High Perform Comput Netw Storage Anal | 2023 Nov |
CeLab, a microfluidic platform for the study of life history traits, reveals metformin and SGK-1 regulation of longevity and reproductive span. | Sohrabi S, Cota V, Murphy CT | Lab on a chip | 37221962 | Lab Chip | 2023 Jun 13 |
Neuronal activation of G(αq) EGL-30/GNAQ late in life rejuvenates cognition across species. | Stevenson ME, Bieri G, Kaletsky R, St Ange J, Remesal L, Pratt KJB, Zhou S, Weng Y, Murphy CT, Villeda SA | Cell reports | 37713310 | Cell Rep | 2023 Sep 26 |
Life, the genome and everything. | Rosenberg SM | Journal of bacteriology | 38018999 | J Bacteriol | 2023 Dec 19 |
IRE1α silences dsRNA to prevent taxane-induced pyroptosis in triple-negative breast cancer. | Xu L, Peng F, Luo Q, Ding Y, Yuan F, Zheng L, He W, Zhang SS, Fu X, Liu J, Mutlu AS, Wang S, Nehring RB, Li X, Tang Q, Li C, Lv X, Dobrolecki LE, Zhang W, Han D, Zhao N, Jaehnig E, Wang J, Wu W, Graham DA, Li Y, Chen R, Peng W, Chen Y, Catic A, Zhang Z, Zhang B, Mustoe AM, Koong AC, Miles G, Lewis MT, Wang MC, Rosenberg SM, O'Malley BW, Westbrook TF, Xu H, Zhang XH, Osborne CK, Li JB, Ellis MJ, Rimawi MF, Rosen JM, Chen X | Cell | 39419025 | Cell | 2024 Dec 12 |
Genomic mapping of DNA-repair reaction intermediates in living cells with engineered DNA structure-trap proteins. | Liu J, Mei Q, Nimer S, Fitzgerald DM, Rosenberg SM | Methods in enzymology | 34776211 | Methods Enzymol | 2021 |
Rapid profiling of DNA replication dynamics using mass spectrometry-based analysis of nascent DNA. | Ashour ME, Byrum AK, Meroni A, Xia J, Singh S, Galletto R, Rosenberg SM, Vindigni A, Mosammaparast N | The Journal of cell biology | 36795402 | J Cell Biol | 2023 Apr 3 |
Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies. | Li Y, Xiao X, Li J, Han Y, Cheng C, Fernandes GF, Slewitzke SE, Rosenberg SM, Zhu M, Byun J, Bossé Y, McKay JD, Albanes D, Lam S, Tardon A, Chen C, Bojesen SE, Landi MT, Johansson M, Risch A, Bickeböller H, Wichmann HE, Christiani DC, Rennert G, Arnold SM, Goodman GE, Field JK, Davies MPA, Shete S, Marchand LL, Liu G, Hung RJ, Andrew AS, Kiemeney LA, Sun R, Zienolddiny S, Grankvist K, Johansson M, Caporaso NE, Cox A, Hong YC, Lazarus P, Schabath MB, Aldrich MC, Schwartz AG, Gorlov I, Purrington KS, Yang P, Liu Y, Bailey-Wilson JE, Pinney SM, Mandal D, Willey JC, Gaba C, Brennan P, Xia J, Shen H, Amos CI | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology | 38180474 | Cancer Epidemiol Biomarkers Prev | 2024 Mar 1 |
Biology before the SOS Response-DNA Damage Mechanisms at Chromosome Fragile Sites. | Fitzgerald DM, Rosenberg SM | Cells | 34571923 | Cells | 2021 Sep 1 |
Drugging evolution of antibiotic resistance at a regulatory network hub. | Zhai Y, Pribis JP, Dooling SW, Garcia-Villada L, Minnick PJ, Xia J, Liu J, Mei Q, Fitzgerald DM, Herman C, Hastings PJ, Costa-Mattioli M, Rosenberg SM | Science advances | 37352342 | Sci Adv | 2023 Jun 23 |
Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer. | Byun J, Han Y, Li Y, Xia J, Long E, Choi J, Xiao X, Zhu M, Zhou W, Sun R, Bossé Y, Song Z, Schwartz A, Lusk C, Rafnar T, Stefansson K, Zhang T, Zhao W, Pettit RW, Liu Y, Li X, Zhou H, Walsh KM, Gorlov I, Gorlova O, Zhu D, Rosenberg SM, Pinney S, Bailey-Wilson JE, Mandal D, de Andrade M, Gaba C, Willey JC, You M, Anderson M, Wiencke JK, Albanes D, Lam S, Tardon A, Chen C, Goodman G, Bojeson S, Brenner H, Landi MT, Chanock SJ, Johansson M, Muley T, Risch A, Wichmann HE, Bickeböller H, Christiani DC, Rennert G, Arnold S, Field JK, Shete S, Le Marchand L, Melander O, Brunnstrom H, Liu G, Andrew AS, Kiemeney LA, Shen H, Zienolddiny S, Grankvist K, Johansson M, Caporaso N, Cox A, Hong YC, Yuan JM, Lazarus P, Schabath MB, Aldrich MC, Patel A, Lan Q, Rothman N, Taylor F, Kachuri L, Witte JS, Sakoda LC, Spitz M, Brennan P, Lin X, McKay J, Hung RJ, Amos CI | Nature genetics | 35915169 | Nat Genet | 2022 Aug |
Stress-Induced Mutagenesis, Gambler Cells, and Stealth Targeting Antibiotic-Induced Evolution. | Pribis JP, Zhai Y, Hastings PJ, Rosenberg SM | mBio | 35658528 | mBio | 2022 Jun 28 |
Hyperactivation of monocytes and macrophages in MCI patients contributes to the progression of Alzheimer's disease. | Munawara U, Catanzaro M, Xu W, Tan C, Hirokawa K, Bosco N, Dumoulin D, Khalil A, Larbi A, Lévesque S, Ramassamy C, Barron AE, Cunnane S, Beauregard PB, Bellenger JP, Rodrigues S, Desroches M, Witkowski JM, Laurent B, Frost EH, Fulop T | Immunity & ageing : I & A | 34154615 | Immun Ageing | 2021 Jun 21 |
Real-Time Monitoring of Multitarget Antimicrobial Mechanisms of Peptoids Using Label-Free Imaging with Optical Diffraction Tomography. | Kim M, Cheon Y, Shin D, Choi J, Nielsen JE, Jeong MS, Nam HY, Kim SH, Lund R, Jenssen H, Barron AE, Lee S, Seo J | Advanced science (Weinheim, Baden-Wurttemberg, Germany) | 37341246 | Adv Sci (Weinh) | 2023 Aug |
The anti-inflammatory effects of photobiomodulation are mediated by cytokines: Evidence from a mouse model of inflammation. | Shamloo S, Defensor E, Ciari P, Ogawa G, Vidano L, Lin JS, Fortkort JA, Shamloo M, Barron AE | Frontiers in neuroscience | 37090796 | Front Neurosci | 2023 |
The activity of antimicrobial peptoids against multidrug-resistant ocular pathogens. | Sara M, Yasir M, Kalaiselvan P, Hui A, Kuppusamy R, Kumar N, Chakraborty S, Yu TT, Wong EHH, Molchanova N, Jenssen H, Lin JS, Barron AE, Willcox M | Contact lens & anterior eye : the journal of the British Contact Lens Association | 38341309 | Cont Lens Anterior Eye | 2024 Apr |
Peptide-mimetic treatment of Pseudomonas aeruginosa in a mouse model of respiratory infection. | Moule MG, Benjamin AB, Burger ML, Herlan C, Lebedev M, Lin JS, Koster KJ, Wavare N, Adams LG, Bräse S, Munoz-Medina R, Cannon CL, Barron AE, Cirillo JD | Communications biology | 39174819 | Commun Biol | 2024 Aug 22 |
Author Correction: Peptide-mimetic treatment of Pseudomonas aeruginosa in a mouse model of respiratory infection. | Moule MG, Benjamin AB, Burger ML, Herlan C, Lebedev M, Lin JS, Koster KJ, Wavare N, Adams LG, Bräse S, Munoz-Medina R, Cannon CL, Barron AE, Cirillo JD | Communications biology | 39271756 | Commun Biol | 2024 Sep 13 |
Self-Assembly of Antimicrobial Peptoids Impacts Their Biological Effects on ESKAPE Bacterial Pathogens. | Nielsen JE, Alford MA, Yung DBY, Molchanova N, Fortkort JA, Lin JS, Diamond G, Hancock REW, Jenssen H, Pletzer D, Lund R, Barron AE | ACS infectious diseases | 35175731 | ACS Infect Dis | 2022 Mar 11 |
Efficacy of Cathelicidin-Mimetic Antimicrobial Peptoids against Staphylococcus aureus. | Benjamin AB, Moule MG, Didwania MK, Hardy J, Saenkham-Huntsinger P, Sule P, Nielsen JE, Lin JS, Contag CH, Barron AE, Cirillo JD | Microbiology spectrum | 35467395 | Microbiol Spectr | 2022 Jun 29 |
Potent Antiviral Activity against HSV-1 and SARS-CoV-2 by Antimicrobial Peptoids. | Diamond G, Molchanova N, Herlan C, Fortkort JA, Lin JS, Figgins E, Bopp N, Ryan LK, Chung D, Adcock RS, Sherman M, Barron AE | Pharmaceuticals (Basel, Switzerland) | 33807248 | Pharmaceuticals (Basel) | 2021 Mar 31 |
Membrane-acting biomimetic peptoids against visceral leishmaniasis. | Kumar V, Lin JS, Molchanova N, Fortkort JA, Reckmann C, Bräse S, Jenssen H, Barron AE, Chugh A | FEBS open bio | 36683396 | FEBS Open Bio | 2023 Mar |
Acid-degradable lipid nanoparticles enhance the delivery of mRNA. | Zhao S, Gao K, Han H, Stenzel M, Yin B, Song H, Lawanprasert A, Nielsen JE, Sharma R, Arogundade OH, Pimcharoen S, Chen YJ, Paul A, Tuma J, Collins MG, Wyle Y, Cranick MG, Burgstone BW, Perez BS, Barron AE, Smith AM, Lee HY, Wang A, Murthy N | Nature nanotechnology | 39179796 | Nat Nanotechnol | 2024 Nov |
Targeting Impaired Antimicrobial Immunity in the Brain for the Treatment of Alzheimer's Disease. | Fulop T, Tripathi S, Rodrigues S, Desroches M, Bunt T, Eiser A, Bernier F, Beauregard PB, Barron AE, Khalil A, Plotka A, Hirokawa K, Larbi A, Bocti C, Laurent B, Frost EH, Witkowski JM | Neuropsychiatric disease and treatment | 33976546 | Neuropsychiatr Dis Treat | 2021 |
Targeting Infectious Agents as a Therapeutic Strategy in Alzheimer's Disease. | Fülöp T, Munawara U, Larbi A, Desroches M, Rodrigues S, Catanzaro M, Guidolin A, Khalil A, Bernier F, Barron AE, Hirokawa K, Beauregard PB, Dumoulin D, Bellenger JP, Witkowski JM, Frost E | CNS drugs | 32458360 | CNS Drugs | 2020 Jul |
Anti-persister and Anti-biofilm Activity of Self-Assembled Antimicrobial Peptoid Ellipsoidal Micelles. | Lin JS, Bekale LA, Molchanova N, Nielsen JE, Wright M, Bacacao B, Diamond G, Jenssen H, Santa Maria PL, Barron AE | ACS infectious diseases | 36018039 | ACS Infect Dis | 2022 Sep 9 |
Pf bacteriophages hinder sputum antibiotic diffusion via electrostatic binding. | Chen Q, Cai P, Chang THW, Burgener E, Kratochvil MJ, Gupta A, Hargil A, Secor PR, Nielsen JE, Barron AE, Milla C, Heilshorn SC, Spakowitz A, Bollyky PL | bioRxiv : the preprint server for biology | 38496625 | bioRxiv | 2024 Mar 10 |
Antiviral Effect of Antimicrobial Peptoid TM9 and Murine Model of Respiratory Coronavirus Infection. | Lebedev M, Benjamin AB, Kumar S, Molchanova N, Lin JS, Koster KJ, Leibowitz JL, Barron AE, Cirillo JD | Pharmaceutics | 38675125 | Pharmaceutics | 2024 Mar 27 |
Antiviral effect of peptoids on hepatitis B virus infection in cell culture. | Murayama A, Igarashi H, Yamada N, Aly HH, Molchanova N, Lin JS, Nishitsuji H, Shimotohno K, Muramatsu M, Barron AE, Kato T | Antiviral research | 38272318 | Antiviral Res | 2024 Mar |
Supramolecular Peptoid Structure Strengthens Complexation with Polyacrylic Acid Microgels. | Zhao W, Lin JS, Nielsen JE, Sørensen K, Wadurkar AS, Ji J, Barron AE, Nangia S, Libera MR | Biomacromolecules | 38240722 | Biomacromolecules | 2024 Feb 12 |
Ethylene oxide graft copolymers reduce the immunogenicity of lipid nanoparticles. | Qi Y, Han H, Liu A, Zhao S, Lawanprasert A, Nielsen JE, Choudhary H, Liang D, Barron AE, Murthy N | RSC advances | 39309654 | RSC Adv | 2024 Sep 18 |
From Global to Nano: A Geographical Perspective of Aggregatibacter actinomycetemcomitans. | Ryder MI, Fine DH, Barron AE | Pathogens (Basel, Switzerland) | 39452709 | Pathogens | 2024 Sep 27 |
From start to finish-a molecular link in wound repair. | Yun S, Greco V | Science (New York, N.Y.) | 35143296 | Science | 2022 Feb 11 |
Live imaging reveals chromatin compaction transitions and dynamic transcriptional bursting during stem cell differentiation in vivo. | May D, Yun S, Gonzalez DG, Park S, Chen Y, Lathrop E, Cai B, Xin T, Zhao H, Wang S, Gonzalez LE, Cockburn K, Greco V | eLife | 36880644 | Elife | 2023 Mar 7 |
Mechanisms of skin vascular maturation and maintenance captured by longitudinal imaging of live mice. | Kam CY, Singh ID, Gonzalez DG, Matte-Martone C, Solá P, Solanas G, Bonjoch J, Marsh E, Hirschi KK, Greco V | Cell | 37167971 | Cell | 2023 May 25 |
Probing the rules of cell coordination in live tissues by interpretable machine learning based on graph neural networks. | Yamamoto T, Cockburn K, Greco V, Kawaguchi K | PLoS computational biology | 36067226 | PLoS Comput Biol | 2022 Sep |
Injury prevents Ras mutant cell expansion in mosaic skin. | Gallini S, Annusver K, Rahman NT, Gonzalez DG, Yun S, Matte-Martone C, Xin T, Lathrop E, Suozzi KC, Kasper M, Greco V | Nature | 37344586 | Nature | 2023 Jul |
Correction: Cell cycle controls long-range calcium signaling in the regenerating epidermis. | Moore JL, Bhaskar D, Gao F, Matte-Martone C, Du S, Lathrop E, Ganesan S, Shao L, Norris R, Sanz NC, Annusver K, Kasper M, Cox A, Hendry C, Rieck B, Krishnaswamy S, Greco V | The Journal of cell biology | 38477880 | J Cell Biol | 2024 Apr 1 |
Metabolic rewiring in skin epidermis drives tolerance to oncogenic mutations. | Hemalatha A, Li Z, Gonzalez DG, Matte-Martone C, Tai K, Lathrop E, Gil D, Ganesan S, Gonzalez LE, Skala M, Perry RJ, Greco V | Nature cell biology | 39762578 | Nat Cell Biol | 2025 Feb |
Functional cell death, corneoptosis, requires temporally controlled intracellular acidification. | Moore JL, Greco V | Proceedings of the National Academy of Sciences of the United States of America | 33986147 | Proc Natl Acad Sci U S A | 2021 Jun 1 |
Cell cycle controls long-range calcium signaling in the regenerating epidermis. | Moore JL, Bhaskar D, Gao F, Matte-Martone C, Du S, Lathrop E, Ganesan S, Shao L, Norris R, Campamà Sanz N, Annusver K, Kasper M, Cox A, Hendry C, Rieck B, Krishnaswamy S, Greco V | The Journal of cell biology | 37102999 | J Cell Biol | 2023 Jul 3 |
Skin-resident immune cells actively coordinate their distribution with epidermal cells during homeostasis. | Park S, Matte-Martone C, Gonzalez DG, Lathrop EA, May DP, Pineda CM, Moore JL, Boucher JD, Marsh E, Schmitter-Sánchez A, Cockburn K, Markova O, Bellaïche Y, Greco V | Nature cell biology | 33958758 | Nat Cell Biol | 2021 May |
Gradual differentiation uncoupled from cell cycle exit generates heterogeneity in the epidermal stem cell layer. | Cockburn K, Annusver K, Gonzalez DG, Ganesan S, May DP, Mesa KR, Kawaguchi K, Kasper M, Greco V | Nature cell biology | 36357619 | Nat Cell Biol | 2022 Dec |
Organ function is preserved despite reorganization of niche architecture in the hair follicle. | Wei H, Du S, Parksong J, Pasolli HA, Matte-Martone C, Regot S, Gonzalez LE, Xin T, Greco V | Cell stem cell | 37419106 | Cell Stem Cell | 2023 Jul 6 |
Oncogenic Kras induces spatiotemporally specific tissue deformation through converting pulsatile into sustained ERK activation. | Xin T, Gallini S, Wei H, Gonzalez DG, Matte-Martone C, Machida H, Fujiwara H, Pasolli HA, Suozzi KC, Gonzalez LE, Regot S, Greco V | Nature cell biology | 38689013 | Nat Cell Biol | 2024 Jun |
A Spatiotemporal Compartmentalization of Glucose Metabolism Guides Mammalian Gastrulation Progression. | Cao D, Zhong L, Hemalatha A, Bergmann J, Cox AL, Greco V, Sozen B | bioRxiv : the preprint server for biology | 37333168 | bioRxiv | 2023 Jun 8 |
Selective utilization of glucose metabolism guides mammalian gastrulation. | Cao D, Bergmann J, Zhong L, Hemalatha A, Dingare C, Jensen T, Cox AL, Greco V, Steventon B, Sozen B | Nature | 39415005 | Nature | 2024 Oct |
Dissecting dual roles of MyoD during lineage conversion to mature myocytes and myogenic stem cells. | Yagi M, Ji F, Charlton J, Cristea S, Messemer K, Horwitz N, Di Stefano B, Tsopoulidis N, Hoetker MS, Huebner AJ, Bar-Nur O, Almada AE, Yamamoto M, Patelunas A, Goldhamer DJ, Wagers AJ, Michor F, Meissner A, Sadreyev RI, Hochedlinger K | Genes & development | 34413137 | Genes Dev | 2021 Sep 1 |
Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species. | Tabebordbar M, Lagerborg KA, Stanton A, King EM, Ye S, Tellez L, Krunnfusz A, Tavakoli S, Widrick JJ, Messemer KA, Troiano EC, Moghadaszadeh B, Peacker BL, Leacock KA, Horwitz N, Beggs AH, Wagers AJ, Sabeti PC | Cell | 34506722 | Cell | 2021 Sep 16 |
In Situ Modification of Tissue Stem and Progenitor Cell Genomes. | Goldstein JM, Tabebordbar M, Zhu K, Wang LD, Messemer KA, Peacker B, Ashrafi Kakhki S, Gonzalez-Celeiro M, Shwartz Y, Cheng JKW, Xiao R, Barungi T, Albright C, Hsu YC, Vandenberghe LH, Wagers AJ | Cell reports | 31018138 | Cell Rep | 2019 Apr 23 |
High-efficiency purification of divergent AAV serotypes using AAVX affinity chromatography. | Florea M, Nicolaou F, Pacouret S, Zinn EM, Sanmiguel J, Andres-Mateos E, Unzu C, Wagers AJ, Vandenberghe LH | Molecular therapy. Methods & clinical development | 36654797 | Mol Ther Methods Clin Dev | 2023 Mar 9 |
Harvard HIV and Aging Workshop: Perspectives and Priorities from Claude D. Pepper Centers and Centers for AIDS Research. | Montano M, Bhasin S, D'Aquila RT, Erlandson KM, Evans WJ, Funderburg NT, Justice A, Ndhlovu LC, Ojikutu B, Pahor M, Pahwa S, Ryan AS, Schrack J, Schultz MB, Sebastiani P, Sinclair DA, Tripp J, Walker B, Womack JA, Yung R, Reeves RK | AIDS research and human retroviruses | 31456412 | AIDS Res Hum Retroviruses | 2019 Nov-Dec |
Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance. | Costford SR, Brouwers B, Hopf ME, Sparks LM, Dispagna M, Gomes AP, Cornnell HH, Petucci C, Phelan P, Xie H, Yi F, Walter GA, Osborne TF, Sinclair DA, Mynatt RL, Ayala JE, Gardell SJ, Smith SR | Molecular metabolism | 29146412 | Mol Metab | 2018 Jan |
Impairment of an Endothelial NAD(+)-H(2)S Signaling Network Is a Reversible Cause of Vascular Aging. | Das A, Huang GX, Bonkowski MS, Longchamp A, Li C, Schultz MB, Kim LJ, Osborne B, Joshi S, Lu Y, Treviño-Villarreal JH, Kang MJ, Hung TT, Lee B, Williams EO, Igarashi M, Mitchell JR, Wu LE, Turner N, Arany Z, Guarente L, Sinclair DA | Cell | 29570999 | Cell | 2018 Mar 22 |
Multigenerational obesity-induced perturbations in oocyte-secreted factor signalling can be ameliorated by exercise and nicotinamide mononucleotide. | Bertoldo MJ, Uddin GM, Youngson NA, Agapiou D, Walters KA, Sinclair DA, Morris MJ, Gilchrist RB | Human reproduction open | 30895251 | Hum Reprod Open | 2018 |
Voluntary exercise normalizes the proteomic landscape in muscle and brain and improves the phenotype of progeroid mice. | Ross JM, Coppotelli G, Branca RM, Kim KM, Lehtiö J, Sinclair DA, Olson L | Aging cell | 31489782 | Aging Cell | 2019 Dec |
Dynamic Acetylation of Phosphoenolpyruvate Carboxykinase Toggles Enzyme Activity between Gluconeogenic and Anaplerotic Reactions. | Latorre-Muro P, Baeza J, Armstrong EA, Hurtado-Guerrero R, Corzana F, Wu LE, Sinclair DA, López-Buesa P, Carrodeguas JA, Denu JM | Molecular cell | 30193097 | Mol Cell | 2018 Sep 6 |
Assays for NAD(+)-Dependent Reactions and NAD(+) Metabolites. | Schultz MB, Lu Y, Braidy N, Sinclair DA | Methods in molecular biology (Clifton, N.J.) | 30097862 | Methods Mol Biol | 2018 |
Resveratrol Improves Vascular Function and Mitochondrial Number but Not Glucose Metabolism in Older Adults. | Pollack RM, Barzilai N, Anghel V, Kulkarni AS, Golden A, O'Broin P, Sinclair DA, Bonkowski MS, Coleville AJ, Powell D, Kim S, Moaddel R, Stein D, Zhang K, Hawkins M, Crandall JP | The journals of gerontology. Series A, Biological sciences and medical sciences | 28329397 | J Gerontol A Biol Sci Med Sci | 2017 Nov 9 |
Sirtuins and NAD(+) in the Development and Treatment of Metabolic and Cardiovascular Diseases. | Kane AE, Sinclair DA | Circulation research | 30355082 | Circ Res | 2018 Sep 14 |
Publisher Correction: Longitudinal analysis of biomarker data from a personalized nutrition platform in healthy subjects. | Westerman K, Reaver A, Roy C, Ploch M, Sharoni E, Nogal B, Sinclair DA, Katz DL, Blumberg JB, Blander G | Scientific reports | 30405144 | Sci Rep | 2018 Nov 8 |
Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage. | Bolderson E, Burgess JT, Li J, Gandhi NS, Boucher D, Croft LV, Beard S, Plowman JJ, Suraweera A, Adams MN, Naqi A, Zhang SD, Sinclair DA, O'Byrne KJ, Richard DJ | Nature communications | 31796734 | Nat Commun | 2019 Dec 3 |
Amino Acid Restriction Triggers Angiogenesis via GCN2/ATF4 Regulation of VEGF and H(2)S Production. | Longchamp A, Mirabella T, Arduini A, MacArthur MR, Das A, Treviño-Villarreal JH, Hine C, Ben-Sahra I, Knudsen NH, Brace LE, Reynolds J, Mejia P, Tao M, Sharma G, Wang R, Corpataux JM, Haefliger JA, Ahn KH, Lee CH, Manning BD, Sinclair DA, Chen CS, Ozaki CK, Mitchell JR | Cell | 29570992 | Cell | 2018 Mar 22 |
Sirtuin activators and inhibitors: Promises, achievements, and challenges. | Dai H, Sinclair DA, Ellis JL, Steegborn C | Pharmacology & therapeutics | 29577959 | Pharmacol Ther | 2018 Aug |
Quantitative proteomic analysis of extracellular vesicle subgroups isolated by an optimized method combining polymer-based precipitation and size exclusion chromatography. | Martínez-Greene JA, Hernández-Ortega K, Quiroz-Baez R, Resendis-Antonio O, Pichardo-Casas I, Sinclair DA, Budnik B, Hidalgo-Miranda A, Uribe-Querol E, Ramos-Godínez MDP, Martínez-Martínez E | Journal of extracellular vesicles | 33936570 | J Extracell Vesicles | 2021 Apr |
NAD(+) Repletion Rescues Female Fertility during Reproductive Aging. | Bertoldo MJ, Listijono DR, Ho WJ, Riepsamen AH, Goss DM, Richani D, Jin XL, Mahbub S, Campbell JM, Habibalahi A, Loh WN, Youngson NA, Maniam J, Wong ASA, Selesniemi K, Bustamante S, Li C, Zhao Y, Marinova MB, Kim LJ, Lau L, Wu RM, Mikolaizak AS, Araki T, Le Couteur DG, Turner N, Morris MJ, Walters KA, Goldys E, O'Neill C, Gilchrist RB, Sinclair DA, Homer HA, Wu LE | Cell reports | 32049001 | Cell Rep | 2020 Feb 11 |
Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. | Tarantini S, Valcarcel-Ares MN, Toth P, Yabluchanskiy A, Tucsek Z, Kiss T, Hertelendy P, Kinter M, Ballabh P, Süle Z, Farkas E, Baur JA, Sinclair DA, Csiszar A, Ungvari Z | Redox biology | 31015147 | Redox Biol | 2019 Jun |
Impacts of obesity, maternal obesity and nicotinamide mononucleotide supplementation on sperm quality in mice. | Youngson NA, Uddin GM, Das A, Martinez C, Connaughton HS, Whiting S, Yu J, Sinclair DA, Aitken RJ, Morris MJ | Reproduction (Cambridge, England) | 31226694 | Reproduction | 2019 Aug 1 |
Molecular and Cellular Characterization of SIRT1 Allosteric Activators. | Schultz MB, Rinaldi C, Lu Y, Amorim JA, Sinclair DA | Methods in molecular biology (Clifton, N.J.) | 31087296 | Methods Mol Biol | 2019 |
Multiple basal cell carcinomas in a patient with myotonic dystrophy type 1. | Feng J, LaChance A, Sinclair DA, Asgari MM | BMJ case reports | 30852496 | BMJ Case Rep | 2019 Mar 8 |
Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice. | Mitchell SJ, Bernier M, Aon MA, Cortassa S, Kim EY, Fang EF, Palacios HH, Ali A, Navas-Enamorado I, Di Francesco A, Kaiser TA, Waltz TB, Zhang N, Ellis JL, Elliott PJ, Frederick DW, Bohr VA, Schmidt MS, Brenner C, Sinclair DA, Sauve AA, Baur JA, de Cabo R | Cell metabolism | 29514072 | Cell Metab | 2018 Mar 6 |
Mitohormesis and metabolic health: The interplay between ROS, cAMP and sirtuins. | Palmeira CM, Teodoro JS, Amorim JA, Steegborn C, Sinclair DA, Rolo AP | Free radical biology & medicine | 31349039 | Free Radic Biol Med | 2019 Sep |
NAD(+) in Brain Aging and Neurodegenerative Disorders. | Lautrup S, Sinclair DA, Mattson MP, Fang EF | Cell metabolism | 31577933 | Cell Metab | 2019 Oct 1 |
Epigenetic changes during aging and their reprogramming potential. | Kane AE, Sinclair DA | Critical reviews in biochemistry and molecular biology | 30822165 | Crit Rev Biochem Mol Biol | 2019 Feb |
Frailty biomarkers in humans and rodents: Current approaches and future advances. | Kane AE, Sinclair DA | Mechanisms of ageing and development | 31002925 | Mech Ageing Dev | 2019 Jun |
Telomere Dysfunction Induces Sirtuin Repression that Drives Telomere-Dependent Disease. | Amano H, Chaudhury A, Rodriguez-Aguayo C, Lu L, Akhanov V, Catic A, Popov YV, Verdin E, Johnson H, Stossi F, Sinclair DA, Nakamaru-Ogiso E, Lopez-Berestein G, Chang JT, Neilson JR, Meeker A, Finegold M, Baur JA, Sahin E | Cell metabolism | 30930169 | Cell Metab | 2019 Jun 4 |
Longitudinal analysis of biomarker data from a personalized nutrition platform in healthy subjects. | Westerman K, Reaver A, Roy C, Ploch M, Sharoni E, Nogal B, Sinclair DA, Katz DL, Blumberg JB, Blander G | Scientific reports | 30279436 | Sci Rep | 2018 Oct 2 |
Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice. | Wahl D, Solon-Biet SM, Wang QP, Wali JA, Pulpitel T, Clark X, Raubenheimer D, Senior AM, Sinclair DA, Cooney GJ, de Cabo R, Cogger VC, Simpson SJ, Le Couteur DG | Cell reports | 30463018 | Cell Rep | 2018 Nov 20 |
Nicotinamide mononucleotide (NMN) supplementation ameliorates the impact of maternal obesity in mice: comparison with exercise. | Uddin GM, Youngson NA, Doyle BM, Sinclair DA, Morris MJ | Scientific reports | 29118320 | Sci Rep | 2017 Nov 8 |
Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles. | Bonora M, Wieckowski MR, Sinclair DA, Kroemer G, Pinton P, Galluzzi L | Nature reviews. Cardiology | 30177752 | Nat Rev Cardiol | 2019 Jan |
Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence. | Rajman L, Chwalek K, Sinclair DA | Cell metabolism | 29514064 | Cell Metab | 2018 Mar 6 |
Influence of donor age on induced pluripotent stem cells. | Lo Sardo V, Ferguson W, Erikson GA, Topol EJ, Baldwin KK, Torkamani A | Nature biotechnology | 27941802 | Nat Biotechnol | 2017 Jan |
Genomic integrity of human induced pluripotent stem cells across nine studies in the NHLBI NextGen program. | Kanchan K, Iyer K, Yanek LR, Carcamo-Orive I, Taub MA, Malley C, Baldwin K, Becker LC, Broeckel U, Cheng L, Cowan C, D'Antonio M, Frazer KA, Quertermous T, Mostoslavsky G, Murphy G, Rabinovitch M, Rader DJ, Steinberg MH, Topol E, Yang W, Knowles JW, Jaquish CE, Ruczinski I, Mathias RA | Stem cell research | 32442913 | Stem Cell Res | 2020 Jul |
Rates of contributory de novo mutation in high and low-risk autism families. | Yoon S, Munoz A, Yamrom B, Lee YH, Andrews P, Marks S, Wang Z, Reeves C, Winterkorn L, Krieger AM, Buja A, Pradhan K, Ronemus M, Baldwin KK, Levy D, Wigler M, Iossifov I | Communications biology | 34471188 | Commun Biol | 2021 Sep 1 |
Transcriptional profiling of isogenic Friedreich ataxia neurons and effect of an HDAC inhibitor on disease signatures. | Lai JI, Nachun D, Petrosyan L, Throesch B, Campau E, Gao F, Baldwin KK, Coppola G, Gottesfeld JM, Soragni E | The Journal of biological chemistry | 30552117 | J Biol Chem | 2019 Feb 8 |
Unveiling the Role of the Most Impactful Cardiovascular Risk Locus through Haplotype Editing. | Lo Sardo V, Chubukov P, Ferguson W, Kumar A, Teng EL, Duran M, Zhang L, Cost G, Engler AJ, Urnov F, Topol EJ, Torkamani A, Baldwin KK | Cell | 30528432 | Cell | 2018 Dec 13 |
Diverse reprogramming codes for neuronal identity. | Tsunemoto R, Lee S, Szűcs A, Chubukov P, Sokolova I, Blanchard JW, Eade KT, Bruggemann J, Wu C, Torkamani A, Sanna PP, Baldwin KK | Nature | 29743677 | Nature | 2018 May |
Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics. | Yang AC, du Bois H, Olsson N, Gate D, Lehallier B, Berdnik D, Brewer KD, Bertozzi CR, Elias JE, Wyss-Coray T | Journal of the American Chemical Society | 29775058 | J Am Chem Soc | 2018 Jun 13 |
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains. | Pluvinage JV, Haney MS, Smith BAH, Sun J, Iram T, Bonanno L, Li L, Lee DP, Morgens DW, Yang AC, Shuken SR, Gate D, Scott M, Khatri P, Luo J, Bertozzi CR, Bassik MC, Wyss-Coray T | Nature | 30944478 | Nature | 2019 Apr |
A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. | Tabula Muris Consortium | Nature | 32669714 | Nature | 2020 Jul |
Papain-based Single Cell Isolation of Primary Murine Brain Endothelial Cells Using Flow Cytometry. | Yousef H, Czupalla CJ, Lee D, Butcher EC, Wyss-Coray T | Bio-protocol | 31032379 | Bio Protoc | 2018 Nov 20 |
Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1. | Yousef H, Czupalla CJ, Lee D, Chen MB, Burke AN, Zera KA, Zandstra J, Berber E, Lehallier B, Mathur V, Nair RV, Bonanno LN, Yang AC, Peterson T, Hadeiba H, Merkel T, Körbelin J, Schwaninger M, Buckwalter MS, Quake SR, Butcher EC, Wyss-Coray T | Nature medicine | 31086348 | Nat Med | 2019 Jun |
A neuronal blood marker is associated with mortality in old age. | Kaeser SA, Lehallier B, Thinggaard M, Häsler LM, Apel A, Bergmann C, Berdnik D, Jeune B, Christensen K, Grönke S, Partridge L, Wyss-Coray T, Mengel-From J, Jucker M | Nature aging | 37118632 | Nat Aging | 2021 Feb |
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain. | Marschallinger J, Iram T, Zardeneta M, Lee SE, Lehallier B, Haney MS, Pluvinage JV, Mathur V, Hahn O, Morgens DW, Kim J, Tevini J, Felder TK, Wolinski H, Bertozzi CR, Bassik MC, Aigner L, Wyss-Coray T | Nature neuroscience | 31959936 | Nat Neurosci | 2020 Feb |
Human umbilical cord plasma proteins revitalize hippocampal function in aged mice. | Castellano JM, Mosher KI, Abbey RJ, McBride AA, James ML, Berdnik D, Shen JC, Zou B, Xie XS, Tingle M, Hinkson IV, Angst MS, Wyss-Coray T | Nature | 28424512 | Nature | 2017 Apr 27 |
Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age. | Brigger D, Riether C, van Brummelen R, Mosher KI, Shiu A, Ding Z, Zbären N, Gasser P, Guntern P, Yousef H, Castellano JM, Storni F, Graff-Radford N, Britschgi M, Grandgirard D, Hinterbrandner M, Siegrist M, Moullan N, Hofstetter W, Leib SL, Villiger PM, Auwerx J, Villeda SA, Wyss-Coray T, Noti M, Eggel A | Nature metabolism | 32694825 | Nat Metab | 2020 Aug |
Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory Cues. | Chen MB, Yang AC, Yousef H, Lee D, Chen W, Schaum N, Lehallier B, Quake SR, Wyss-Coray T | Cell reports | 32234477 | Cell Rep | 2020 Mar 31 |
Undulating changes in human plasma proteome profiles across the lifespan. | Lehallier B, Gate D, Schaum N, Nanasi T, Lee SE, Yousef H, Moran Losada P, Berdnik D, Keller A, Verghese J, Sathyan S, Franceschi C, Milman S, Barzilai N, Wyss-Coray T | Nature medicine | 31806903 | Nat Med | 2019 Dec |
Physiological blood-brain transport is impaired with age by a shift in transcytosis. | Yang AC, Stevens MY, Chen MB, Lee DP, Stähli D, Gate D, Contrepois K, Chen W, Iram T, Zhang L, Vest RT, Chaney A, Lehallier B, Olsson N, du Bois H, Hsieh R, Cropper HC, Berdnik D, Li L, Wang EY, Traber GM, Bertozzi CR, Luo J, Snyder MP, Elias JE, Quake SR, James ML, Wyss-Coray T | Nature | 32612231 | Nature | 2020 Jul |
Molecular hallmarks of heterochronic parabiosis at single-cell resolution. | Pálovics R, Keller A, Schaum N, Tan W, Fehlmann T, Borja M, Kern F, Bonanno L, Calcuttawala K, Webber J, McGeever A, Tabula Muris Consortium, Luo J, Pisco AO, Karkanias J, Neff NF, Darmanis S, Quake SR, Wyss-Coray T | Nature | 35236985 | Nature | 2022 Mar |
Age-associated molecular changes are deleterious and may modulate life span through diet. | Lee SG, Kaya A, Avanesov AS, Podolskiy DI, Song EJ, Go DM, Jin GD, Hwang JY, Kim EB, Kim DY, Gladyshev VN | Science advances | 28232953 | Sci Adv | 2017 Feb |
Integrating cellular senescence with the concept of damage accumulation in aging: Relevance for clearance of senescent cells. | Ogrodnik M, Salmonowicz H, Gladyshev VN | Aging cell | 30346102 | Aging Cell | 2019 Feb |
Comparative transcriptomics across 14 Drosophila species reveals signatures of longevity. | Ma S, Avanesov AS, Porter E, Lee BC, Mariotti M, Zemskaya N, Guigo R, Moskalev AA, Gladyshev VN | Aging cell | 29671950 | Aging Cell | 2018 Aug |
Germline burden of rare damaging variants negatively affects human healthspan and lifespan. | Shindyapina AV, Zenin AA, Tarkhov AE, Santesmasses D, Fedichev PO, Gladyshev VN | eLife | 32254024 | Elife | 2020 Apr 7 |
LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation. | Simon M, Van Meter M, Ablaeva J, Ke Z, Gonzalez RS, Taguchi T, De Cecco M, Leonova KI, Kogan V, Helfand SL, Neretti N, Roichman A, Cohen HY, Meer MV, Gladyshev VN, Antoch MP, Gudkov AV, Sedivy JM, Seluanov A, Gorbunova V | Cell metabolism | 30853213 | Cell Metab | 2019 Apr 2 |
Multifaceted deregulation of gene expression and protein synthesis with age. | Anisimova AS, Meerson MB, Gerashchenko MV, Kulakovskiy IV, Dmitriev SE, Gladyshev VN | Proceedings of the National Academy of Sciences of the United States of America | 32576685 | Proc Natl Acad Sci U S A | 2020 Jul 7 |
Extrarenal expression of α-klotho, the kidney related longevity gene, in Heterocephalus glaber, the long living Naked Mole Rat. | Morevati M, Mace ML, Egstrand S, Nordholm A, Doganli C, Strand J, Rukov JL, Torsetnes SB, Gorbunova V, Olgaard K, Lewin E | Scientific reports | 34321565 | Sci Rep | 2021 Jul 28 |
The transcriptome of the bowhead whale Balaena mysticetus reveals adaptations of the longest-lived mammal. | Seim I, Ma S, Zhou X, Gerashchenko MV, Lee SG, Suydam R, George JC, Bickham JW, Gladyshev VN | Aging | 25411232 | Aging (Albany NY) | 2014 Oct |
Defining Molecular Basis for Longevity Traits in Natural Yeast Isolates. | Kaya A, Ma S, Wasko B, Lee M, Kaeberlein M, Gladyshev VN | NPJ aging and mechanisms of disease | 27030810 | NPJ Aging Mech Dis | 2015 |
Naked Mole Rat Induced Pluripotent Stem Cells and Their Contribution to Interspecific Chimera. | Lee SG, Mikhalchenko AE, Yim SH, Lobanov AV, Park JK, Choi KH, Bronson RT, Lee CK, Park TJ, Gladyshev VN | Stem cell reports | 29107591 | Stem Cell Reports | 2017 Nov 14 |
Mechanisms of cancer resistance in long-lived mammals. | Seluanov A, Gladyshev VN, Vijg J, Gorbunova V | Nature reviews. Cancer | 29622806 | Nat Rev Cancer | 2018 Jul |
Organization of the Mammalian Metabolome according to Organ Function, Lineage Specialization, and Longevity. | Ma S, Yim SH, Lee SG, Kim EB, Lee SR, Chang KT, Buffenstein R, Lewis KN, Park TJ, Miller RA, Clish CB, Gladyshev VN | Cell metabolism | 26244935 | Cell Metab | 2015 Aug 4 |
Gene expression defines natural changes in mammalian lifespan. | Fushan AA, Turanov AA, Lee SG, Kim EB, Lobanov AV, Yim SH, Buffenstein R, Lee SR, Chang KT, Rhee H, Kim JS, Yang KS, Gladyshev VN | Aging cell | 25677554 | Aging Cell | 2015 Jun |
Comparative genetics of longevity and cancer: insights from long-lived rodents. | Gorbunova V, Seluanov A, Zhang Z, Gladyshev VN, Vijg J | Nature reviews. Genetics | 24981598 | Nat Rev Genet | 2014 Aug |
Convergent evolution of marine mammals is associated with distinct substitutions in common genes. | Zhou X, Seim I, Gladyshev VN | Scientific reports | 26549748 | Sci Rep | 2015 Nov 9 |
Translation fidelity coevolves with longevity. | Ke Z, Mallik P, Johnson AB, Luna F, Nevo E, Zhang ZD, Gladyshev VN, Seluanov A, Gorbunova V | Aging cell | 28707419 | Aging Cell | 2017 Oct |
SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species. | Tian X, Firsanov D, Zhang Z, Cheng Y, Luo L, Tombline G, Tan R, Simon M, Henderson S, Steffan J, Goldfarb A, Tam J, Zheng K, Cornwell A, Johnson A, Yang JN, Mao Z, Manta B, Dang W, Zhang Z, Vijg J, Wolfe A, Moody K, Kennedy BK, Bohmann D, Gladyshev VN, Seluanov A, Gorbunova V | Cell | 31002797 | Cell | 2019 Apr 18 |
A whole lifespan mouse multi-tissue DNA methylation clock. | Meer MV, Podolskiy DI, Tyshkovskiy A, Gladyshev VN | eLife | 30427307 | Elife | 2018 Nov 14 |
Analysis of cancer genomes reveals basic features of human aging and its role in cancer development. | Podolskiy DI, Lobanov AV, Kryukov GV, Gladyshev VN | Nature communications | 27515585 | Nat Commun | 2016 Aug 12 |
Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity. | Ma S, Upneja A, Galecki A, Tsai YM, Burant CF, Raskind S, Zhang Q, Zhang ZD, Seluanov A, Gorbunova V, Clish CB, Miller RA, Gladyshev VN | eLife | 27874830 | Elife | 2016 Nov 22 |
Systematic age-, organ-, and diet-associated ionome remodeling and the development of ionomic aging clocks. | Zhang B, Podolskiy DI, Mariotti M, Seravalli J, Gladyshev VN | Aging cell | 32323920 | Aging Cell | 2020 May |
Intrinsic Versus Extrinsic Cancer Risk Factors and Aging. | Podolskiy DI, Gladyshev VN | Trends in molecular medicine | 27544777 | Trends Mol Med | 2016 Oct |
INK4 locus of the tumor-resistant rodent, the naked mole rat, expresses a functional p15/p16 hybrid isoform. | Tian X, Azpurua J, Ke Z, Augereau A, Zhang ZD, Vijg J, Gladyshev VN, Gorbunova V, Seluanov A | Proceedings of the National Academy of Sciences of the United States of America | 25550505 | Proc Natl Acad Sci U S A | 2015 Jan 27 |
Comparative analysis of genome maintenance genes in naked mole rat, mouse, and human. | MacRae SL, Zhang Q, Lemetre C, Seim I, Calder RB, Hoeijmakers J, Suh Y, Gladyshev VN, Seluanov A, Gorbunova V, Vijg J, Zhang ZD | Aging cell | 25645816 | Aging Cell | 2015 Apr |
Beaver and Naked Mole Rat Genomes Reveal Common Paths to Longevity. | Zhou X, Dou Q, Fan G, Zhang Q, Sanderford M, Kaya A, Johnson J, Karlsson EK, Tian X, Mikhalchenko A, Kumar S, Seluanov A, Zhang ZD, Gorbunova V, Liu X, Gladyshev VN | Cell reports | 32726638 | Cell Rep | 2020 Jul 28 |
Global remodeling of the mouse DNA methylome during aging and in response to calorie restriction. | Sziráki A, Tyshkovskiy A, Gladyshev VN | Aging cell | 29575528 | Aging Cell | 2018 Jun |
Molecular signatures of longevity: Insights from cross-species comparative studies. | Ma S, Gladyshev VN | Seminars in cell & developmental biology | 28800931 | Semin Cell Dev Biol | 2017 Oct |
Gene expression signatures of human cell and tissue longevity. | Seim I, Ma S, Gladyshev VN | NPJ aging and mechanisms of disease | 28721269 | NPJ Aging Mech Dis | 2016 |
Using DNA Methylation Profiling to Evaluate Biological Age and Longevity Interventions. | Petkovich DA, Podolskiy DI, Lobanov AV, Lee SG, Miller RA, Gladyshev VN | Cell metabolism | 28380383 | Cell Metab | 2017 Apr 4 |
Aging: progressive decline in fitness due to the rising deleteriome adjusted by genetic, environmental, and stochastic processes. | Gladyshev VN | Aging cell | 27060562 | Aging Cell | 2016 Aug |
Adaptations to a subterranean environment and longevity revealed by the analysis of mole rat genomes. | Fang X, Seim I, Huang Z, Gerashchenko MV, Xiong Z, Turanov AA, Zhu Y, Lobanov AV, Fan D, Yim SH, Yao X, Ma S, Yang L, Lee SG, Kim EB, Bronson RT, Šumbera R, Buffenstein R, Zhou X, Krogh A, Park TJ, Zhang G, Wang J, Gladyshev VN | Cell reports | 25176646 | Cell Rep | 2014 Sep 11 |
Naked mole rats can undergo developmental, oncogene-induced and DNA damage-induced cellular senescence. | Zhao Y, Tyshkovskiy A, Muñoz-Espín D, Tian X, Serrano M, de Magalhaes JP, Nevo E, Gladyshev VN, Seluanov A, Gorbunova V | Proceedings of the National Academy of Sciences of the United States of America | 29432174 | Proc Natl Acad Sci U S A | 2018 Feb 20 |
Identification and Application of Gene Expression Signatures Associated with Lifespan Extension. | Tyshkovskiy A, Bozaykut P, Borodinova AA, Gerashchenko MV, Ables GP, Garratt M, Khaitovich P, Clish CB, Miller RA, Gladyshev VN | Cell metabolism | 31353263 | Cell Metab | 2019 Sep 3 |
DNA methylation aging clocks: challenges and recommendations. | Bell CG, Lowe R, Adams PD, Baccarelli AA, Beck S, Bell JT, Christensen BC, Gladyshev VN, Heijmans BT, Horvath S, Ideker T, Issa JJ, Kelsey KT, Marioni RE, Reik W, Relton CL, Schalkwyk LC, Teschendorff AE, Wagner W, Zhang K, Rakyan VK | Genome biology | 31767039 | Genome Biol | 2019 Nov 25 |
Deficiency of the 15-kDa selenoprotein led to cytoskeleton remodeling and non-apoptotic membrane blebbing through a RhoA/ROCK pathway. | Bang J, Jang M, Huh JH, Na JW, Shim M, Carlson BA, Tobe R, Tsuji PA, Gladyshev VN, Hatfield DL, Lee BJ | Biochemical and biophysical research communications | 25529450 | Biochem Biophys Res Commun | 2015 Jan 24 |
Organization of the Mammalian Ionome According to Organ Origin, Lineage Specialization, and Longevity. | Ma S, Lee SG, Kim EB, Park TJ, Seluanov A, Gorbunova V, Buffenstein R, Seravalli J, Gladyshev VN | Cell reports | 26549444 | Cell Rep | 2015 Nov 17 |
Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration. | Carlson BA, Tobe R, Yefremova E, Tsuji PA, Hoffmann VJ, Schweizer U, Gladyshev VN, Hatfield DL, Conrad M | Redox biology | 27262435 | Redox Biol | 2016 Oct |
Non-enzymatic molecular damage as a prototypic driver of aging. | Golubev A, Hanson AD, Gladyshev VN | The Journal of biological chemistry | 28264930 | J Biol Chem | 2017 Apr 14 |
Selenocysteine tRNA([Ser]Sec), the Central Component of Selenoprotein Biosynthesis: Isolation, Identification, Modification, and Sequencing. | Carlson BA, Lee BJ, Tsuji PA, Copeland PR, Schweizer U, Gladyshev VN, Hatfield DL | Methods in molecular biology (Clifton, N.J.) | 28917036 | Methods Mol Biol | 2018 |
A Disease or Not a Disease? Aging As a Pathology. | Gladyshev TV, Gladyshev VN | Trends in molecular medicine | 27793599 | Trends Mol Med | 2016 Dec |
Biological age is increased by stress and restored upon recovery. | Poganik JR, Zhang B, Baht GS, Tyshkovskiy A, Deik A, Kerepesi C, Yim SH, Lu AT, Haghani A, Gong T, Hedman AM, Andolf E, Pershagen G, Almqvist C, Clish CB, Horvath S, White JP, Gladyshev VN | Cell metabolism | 37086720 | Cell Metab | 2023 May 2 |
Evolution in Neuromodulation-The Differential Roles of Acetylcholine in Higher Order Association vs. Primary Visual Cortices. | Galvin VC, Arnsten AFT, Wang M | Frontiers in neural circuits | 30210306 | Front Neural Circuits | 2018 |
Persistent Spiking Activity Underlies Working Memory. | Constantinidis C, Funahashi S, Lee D, Murray JD, Qi XL, Wang M, Arnsten AFT | The Journal of neuroscience : the official journal of the Society for Neuroscience | 30089641 | J Neurosci | 2018 Aug 8 |
cAMP-PKA phosphorylation of tau confers risk for degeneration in aging association cortex. | Carlyle BC, Nairn AC, Wang M, Yang Y, Jin LE, Simen AA, Ramos BP, Bordner KA, Craft GE, Davies P, Pletikos M, Šestan N, Arnsten AF, Paspalas CD | Proceedings of the National Academy of Sciences of the United States of America | 24707050 | Proc Natl Acad Sci U S A | 2014 Apr 1 |
Role of KCNQ potassium channels in stress-induced deficit of working memory. | Arnsten AFT, Jin LE, Gamo NJ, Ramos B, Paspalas CD, Morozov YM, Kata A, Bamford NS, Yeckel MF, Kaczmarek LK, El-Hassar L | Neurobiology of stress | 31832507 | Neurobiol Stress | 2019 Nov |
Studies of aging nonhuman primates illuminate the etiology of early-stage Alzheimer's-like neuropathology: An evolutionary perspective. | Arnsten AFT, Datta D, Preuss TM | American journal of primatology | 33960505 | Am J Primatol | 2021 Nov |
Age-related calcium dysregulation linked with tau pathology and impaired cognition in non-human primates. | Datta D, Leslie SN, Wang M, Morozov YM, Yang S, Mentone S, Zeiss C, Duque A, Rakic P, Horvath TL, van Dyck CH, Nairn AC, Arnsten AFT | Alzheimer's & dementia : the journal of the Alzheimer's Association | 33829643 | Alzheimers Dement | 2021 Jun |
Dopamine's Actions in Primate Prefrontal Cortex: Challenges for Treating Cognitive Disorders. | Arnsten AF, Wang M, Paspalas CD | Pharmacological reviews | 26106146 | Pharmacol Rev | 2015 Jul |
Ameliorating treatment-refractory depression with intranasal ketamine: potential NMDA receptor actions in the pain circuitry representing mental anguish. | Opler LA, Opler MG, Arnsten AF | CNS spectrums | 25619798 | CNS Spectr | 2016 Feb |
Novel Dopamine Therapeutics for Cognitive Deficits in Schizophrenia. | Arnsten AF, Girgis RR, Gray DL, Mailman RB | Biological psychiatry | 26946382 | Biol Psychiatry | 2017 Jan 1 |
Core Differences in Synaptic Signaling Between Primary Visual and Dorsolateral Prefrontal Cortex. | Yang ST, Wang M, Paspalas CD, Crimins JL, Altman MT, Mazer JA, Arnsten AFT | Cerebral cortex (New York, N.Y. : 1991) | 29351585 | Cereb Cortex | 2018 Apr 1 |
Unique Molecular Regulation of Higher-Order Prefrontal Cortical Circuits: Insights into the Neurobiology of Schizophrenia. | Datta D, Arnsten AFT | ACS chemical neuroscience | 29470055 | ACS Chem Neurosci | 2018 Sep 19 |
The 7q11.23 Protein DNAJC30 Interacts with ATP Synthase and Links Mitochondria to Brain Development. | Tebbenkamp ATN, Varela L, Choi J, Paredes MI, Giani AM, Song JE, Sestan-Pesa M, Franjic D, Sousa AMM, Liu ZW, Li M, Bichsel C, Koch M, Szigeti-Buck K, Liu F, Li Z, Kawasawa YI, Paspalas CD, Mineur YS, Prontera P, Merla G, Picciotto MR, Arnsten AFT, Horvath TL, Sestan N | Cell | 30318146 | Cell | 2018 Nov 1 |
Targeting Prefrontal Cortical Systems for Drug Development: Potential Therapies for Cognitive Disorders. | Arnsten AF, Wang M | Annual review of pharmacology and toxicology | 26738476 | Annu Rev Pharmacol Toxicol | 2016 |
The Effects of Stress Exposure on Prefrontal Cortex: Translating Basic Research into Successful Treatments for Post-Traumatic Stress Disorder. | Arnsten AF, Raskind MA, Taylor FB, Connor DF | Neurobiology of stress | 25436222 | Neurobiol Stress | 2015 Jan 1 |
Noradrenergic α1-Adrenoceptor Actions in the Primate Dorsolateral Prefrontal Cortex. | Datta D, Yang ST, Galvin VC, Solder J, Luo F, Morozov YM, Arellano J, Duque A, Rakic P, Arnsten AFT, Wang M | The Journal of neuroscience : the official journal of the Society for Neuroscience | 30755491 | J Neurosci | 2019 Apr 3 |
Hypothesis: Tau pathology is an initiating factor in sporadic Alzheimer's disease. | Arnsten AFT, Datta D, Del Tredici K, Braak H | Alzheimer's & dementia : the journal of the Alzheimer's Association | 33075193 | Alzheimers Dement | 2021 Jan |
Mapping Phosphodiesterase 4D (PDE4D) in Macaque Dorsolateral Prefrontal Cortex: Postsynaptic Compartmentalization in Layer III Pyramidal Cell Circuits. | Datta D, Enwright JF, Arion D, Paspalas CD, Morozov YM, Lewis DA, Arnsten AFT | Frontiers in neuroanatomy | 33328902 | Front Neuroanat | 2020 |
Alzheimer's-like pathology in aging rhesus macaques: Unique opportunity to study the etiology and treatment of Alzheimer's disease. | Arnsten AFT, Datta D, Leslie S, Yang ST, Wang M, Nairn AC | Proceedings of the National Academy of Sciences of the United States of America | 31871209 | Proc Natl Acad Sci U S A | 2019 Dec 26 |
Interrogating the Etiology of Sporadic Alzheimer's Disease Using Aging Rhesus Macaques: Cellular, Molecular, and Cortical Circuitry Perspectives. | Datta D | The journals of gerontology. Series A, Biological sciences and medical sciences | 37279946 | J Gerontol A Biol Sci Med Sci | 2023 Aug 27 |
Ultrastructural evidence for impaired mitochondrial fission in the aged rhesus monkey dorsolateral prefrontal cortex. | Morozov YM, Datta D, Paspalas CD, Arnsten AFT | Neurobiology of aging | 28027494 | Neurobiol Aging | 2017 Mar |
A novel dopamine D1 receptor agonist excites delay-dependent working memory-related neuronal firing in primate dorsolateral prefrontal cortex. | Wang M, Datta D, Enwright J, Galvin V, Yang ST, Paspalas C, Kozak R, Gray DL, Lewis DA, Arnsten AFT | Neuropharmacology | 30858103 | Neuropharmacology | 2019 May 15 |
Phosphodiesterase PDE4D Is Decreased in Frontal Cortex of Aged Rats and Positively Correlated With Working Memory Performance and Inversely Correlated With PKA Phosphorylation of Tau. | Leslie SN, Datta D, Christensen KR, van Dyck CH, Arnsten AFT, Nairn AC | Frontiers in aging neuroscience | 33192469 | Front Aging Neurosci | 2020 |
The aged rhesus macaque manifests Braak stage III/IV Alzheimer's-like pathology. | Paspalas CD, Carlyle BC, Leslie S, Preuss TM, Crimins JL, Huttner AJ, van Dyck CH, Rosene DL, Nairn AC, Arnsten AFT | Alzheimer's & dementia : the journal of the Alzheimer's Association | 29241829 | Alzheimers Dement | 2018 May |
Classical complement cascade initiating C1q protein within neurons in the aged rhesus macaque dorsolateral prefrontal cortex. | Datta D, Leslie SN, Morozov YM, Duque A, Rakic P, van Dyck CH, Nairn AC, Arnsten AFT | Journal of neuroinflammation | 31906973 | J Neuroinflammation | 2020 Jan 6 |
Stress weakens prefrontal networks: molecular insults to higher cognition. | Arnsten AF | Nature neuroscience | 26404712 | Nat Neurosci | 2015 Oct |
Ketamine's Antidepressant Actions: Potential Mechanisms in the Primate Medial Prefrontal Circuits That Represent Aversive Experience. | Arnsten AF, Murray JD, Seo H, Lee D | Biological psychiatry | 27079495 | Biol Psychiatry | 2016 May 1 |
Interaction Between HCN and Slack Channels Regulates mPFC Pyramidal Cell Excitability and Working Memory. | Wu J, El-Hassar L, Datta D, Thomas M, Zhang Y, Jenkins DP, DeLuca NJ, Chatterjee M, Gribkoff VK, Arnsten AFT, Kaczmarek LK | Research square | 37205397 | Res Sq | 2023 May 4 |
Remodeling of epigenome and transcriptome landscapes with aging in mice reveals widespread induction of inflammatory responses. | Benayoun BA, Pollina EA, Singh PP, Mahmoudi S, Harel I, Casey KM, Dulken BW, Kundaje A, Brunet A | Genome research | 30858345 | Genome Res | 2019 Apr |
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A platform for rapid exploration of aging and diseases in a naturally short-lived vertebrate. | Harel I, Benayoun BA, Machado B, Singh PP, Hu CK, Pech MF, Valenzano DR, Zhang E, Sharp SC, Artandi SE, Brunet A | Cell | 25684364 | Cell | 2015 Feb 26 |
Chromatin accessibility dynamics reveal novel functional enhancers in C. elegans. | Daugherty AC, Yeo RW, Buenrostro JD, Greenleaf WJ, Kundaje A, Brunet A | Genome research | 29141961 | Genome Res | 2017 Dec |
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Mono-unsaturated fatty acids link H3K4me3 modifiers to C. elegans lifespan. | Han S, Schroeder EA, Silva-García CG, Hebestreit K, Mair WB, Brunet A | Nature | 28379943 | Nature | 2017 Apr 13 |
Lipid Profiles and Signals for Long Life. | Schroeder EA, Brunet A | Trends in endocrinology and metabolism: TEM | 26439976 | Trends Endocrinol Metab | 2015 Nov |
Epigenetic regulation of ageing: linking environmental inputs to genomic stability. | Benayoun BA, Pollina EA, Brunet A | Nature reviews. Molecular cell biology | 26373265 | Nat Rev Mol Cell Biol | 2015 Oct |
Shockingly Early: Chromatin-Mediated Loss of the Heat Shock Response. | Booth LN, Brunet A | Molecular cell | 26295957 | Mol Cell | 2015 Aug 20 |
The Aging Epigenome. | Booth LN, Brunet A | Molecular cell | 27259204 | Mol Cell | 2016 Jun 2 |
The African turquoise killifish: A research organism to study vertebrate aging and diapause. | Hu CK, Brunet A | Aging cell | 29573324 | Aging Cell | 2018 Jun |
Changes in regeneration-responsive enhancers shape regenerative capacities in vertebrates. | Wang W, Hu CK, Zeng A, Alegre D, Hu D, Gotting K, Ortega Granillo A, Wang Y, Robb S, Schnittker R, Zhang S, Alegre D, Li H, Ross E, Zhang N, Brunet A, Sánchez Alvarado A | Science (New York, N.Y.) | 32883834 | Science | 2020 Sep 4 |
Bridging the transgenerational gap with epigenetic memory. | Lim JP, Brunet A | Trends in genetics : TIG | 23410786 | Trends Genet | 2013 Mar |
The African Turquoise Killifish Genome Provides Insights into Evolution and Genetic Architecture of Lifespan. | Valenzano DR, Benayoun BA, Singh PP, Zhang E, Etter PD, Hu CK, Clément-Ziza M, Willemsen D, Cui R, Harel I, Machado BE, Yee MC, Sharp SC, Bustamante CD, Beyer A, Johnson EA, Brunet A | Cell | 26638078 | Cell | 2015 Dec 3 |
The Genetics of Aging: A Vertebrate Perspective. | Singh PP, Demmitt BA, Nath RD, Brunet A | Cell | 30901541 | Cell | 2019 Mar 21 |
Males shorten the life span of C. elegans hermaphrodites via secreted compounds. | Maures TJ, Booth LN, Benayoun BA, Izrayelit Y, Schroeder FC, Brunet A | Science (New York, N.Y.) | 24292626 | Science | 2014 Jan 31 |
Vertebrate diapause preserves organisms long term through Polycomb complex members. | Hu CK, Wang W, Brind'Amour J, Singh PP, Reeves GA, Lorincz MC, Alvarado AS, Brunet A | Science (New York, N.Y.) | 32079766 | Science | 2020 Feb 21 |
Variability in paralimbic dopamine signaling correlates with subjective responses to d-amphetamine. | Smith CT, Dang LC, Cowan RL, Kessler RM, Zald DH | Neuropharmacology | 27174408 | Neuropharmacology | 2016 Sep |
The impact of common dopamine D2 receptor gene polymorphisms on D2/3 receptor availability: C957T as a key determinant in putamen and ventral striatum. | Smith CT, Dang LC, Buckholtz JW, Tetreault AM, Cowan RL, Kessler RM, Zald DH | Translational psychiatry | 28398340 | Transl Psychiatry | 2017 Apr 11 |
Single-Cell Transcriptomic Analysis Defines Heterogeneity and Transcriptional Dynamics in the Adult Neural Stem Cell Lineage. | Dulken BW, Leeman DS, Boutet SC, Hebestreit K, Brunet A | Cell reports | 28099854 | Cell Rep | 2017 Jan 17 |
PKR activation by noncanonical ligands: a 5'-triphosphate requirement versus antisense contamination. | Safran SA, Eckert DM, Leslie EA, Bass BL | RNA (New York, N.Y.) | 31239298 | RNA | 2019 Sep |
C. elegans ADARs antagonize silencing of cellular dsRNAs by the antiviral RNAi pathway. | Reich DP, Tyc KM, Bass BL | Genes & development | 29483152 | Genes Dev | 2018 Feb 1 |
Inverted repeat structures are associated with essential and highly expressed genes on C. elegans autosome distal arms. | Reich DP, Bass BL | RNA (New York, N.Y.) | 30190375 | RNA | 2018 Dec |
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Sorting Out Presenilins in Alzheimer's Disease. | Wolfe MS, Yankner BA | Cell | 27368096 | Cell | 2016 Jun 30 |
Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease. | Lipinski MM, Zheng B, Lu T, Yan Z, Py BF, Ng A, Xavier RJ, Li C, Yankner BA, Scherzer CR, Yuan J | Proceedings of the National Academy of Sciences of the United States of America | 20660724 | Proc Natl Acad Sci U S A | 2010 Aug 10 |
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Caspase-Activated Oligonucleotide Probe. | Yang L, Eberwine JH, Dmochowski IJ | Bioconjugate chemistry | 32786369 | Bioconjug Chem | 2020 Sep 16 |